ライフサイエンスコーパス: structural similarity

1 nct active site architecture despite overall structural similarity.

2 tein surfaces are clustered into groups with structural similarity.

3 ntrons, with which they show mechanistic and structural similarity.

4 arbapenemases given the high degree of their structural similarity.

5 the above three criteria despite their high structural similarity.

6 o align glycan structures and quantify their structural similarity.

7 cal relationships masked by apparent lack of structural similarity.

8 -1 and HIV-2 proteases share a great deal of structural similarity.

9 Y transcription factors revealed significant structural similarity.

10 in each ED3, despite their high sequence and structural similarity.

11 on exposure potential, carcinogenicity, and structural similarity.

12 oy sets and decoy sets that do not show much structural similarity.

13 on neighbours between two nodes to establish structural similarity.

14 ize their alkaloid guests according to their structural similarity.

15 ating oligosaccharides because of their high structural similarity.

16 R-M(5)R) in humans, exhibit a high degree of structural similarity.

17 tein surfaces are grouped by measuring their structural similarities.

18 n of a steroid is challenging owing to their structural similarities.

19 d new language constructions with sufficient structural similarities.

20 age constructions when these have sufficient structural similarities.

21 licing are all DEAH-box helicases that share structural similarities.

22 ey are evolutionarily related and share many structural similarities.

23 and hydrophobic/water surfaces exhibit great structural similarities, a small stabilization of the OH

24 er, a phenomenon we call "trans-hierarchical structural similarity." ALDH16 forms a unique dimer in s

25 nut coallergy (64%-100%) highlights how the structural similarities among their 2S albumins may acco

26 Despite the high structural similarity among them, only homotypic interac

27 Protein Data Bank, also implies large scale structural similarity analyses to retrieve and classify

28 Structural similarities and a core set of genes support

29 ile alpha-motif (SAM) domains have predicted structural similarities and are reported to bind protein

30 also highlight what is known regarding their structural similarities and common mechanisms of regulat

31 hted network of binding sites based on their structural similarities and detecting communities of str

32 , the EID fragmentation patterns reflect the structural similarities and differences among apo-, Zn-,

33 icant challenges that range from identifying structural similarities and differences between models t

34 e Ca(2+)-bound structure of A3, which reveal structural similarities and differences with gelsolin.

35 Despite structural similarities and shared binding partners, inc

36 ee double bonds is a great challenge, due to structural similarities and similar polarities.

37 It combines structural similarity and accounts for evolutionary cons

38 such different evolutionary origins achieved structural similarity and adapted to control by the same

39 The observed structural similarity and common oligomerization pathway

40 ulfate (HS), is challenging because of their structural similarity and facile sulfo losses during ana

41 We show here that, despite the strong structural similarity and functional redundancy of these

42 This process maintains structural similarity and is further supported by this s

43 onists SB269,652 (1) and SB277011A (2) whose structural similarity and pharmacological disparity prov

44 However, because of the structural similarity and the multiple isomeric forms of

45 On the basis of the high structural similarity and tissue coexpression, we here i

46 eceptors share a high degree of sequence and structural similarities, and excessive activity of these

47 Identified compounds were classified by structural similarity, and 15 were selected for secondar

48 he hydrophobins, BslA shares no sequence nor structural similarity, and here we show that the mechani

49 rapidly than Tim9 despite high sequence and structural similarity, and loss of Tim10 is accelerated

50 chemical interaction, the information of the structural similarity, and the information of the finger

51 esistance rapidly to multiple Bt toxins when structural similarities are present among toxins, and ra

52 ne families (DGF-1 and PSA) with no apparent structural similarity are independent derivations of a c

53 forms, where the targets display significant structural similarities as a result of a gene duplicatio

54 Results were discussed by correlating structural similarities, as well as the membrane effects

55 Despite their structural similarity, as ascertained by electronic abso

56 quence similarity, expression similarity and structural similarity, as well as the consistency betwee

57 e particles are shown to exhibit significant structural similarities; being amorphous with a textured

58 The unprecedented structural similarities between an F420-dependent enzyme

59 As a result, the sequence and structural similarities between ancient orthologs have n

60 critical role in neurodegeneration; however, structural similarities between caspase-6 and other casp

61 f that goal (the reconfiguration principle), structural similarities between conscious and unconsciou

62 The structural similarities between dopamine D3 receptor (D3

63 The observed structural similarities between Hsp33's own metastable l

64 Although structural similarities between human and prokaryotic Ar

65 Importantly, despite the structural similarities between human bGP and the two ot

66 Despite the high level of tegument structural similarities between KSHV and alphaherpesviru

67 Here we investigate the structural similarities between liquid water and a compr

68 Structural similarities between RC-DNA and cellular topo

69 Structural similarities between SgK269 and SgK223 includ

70 od of the inhibited enzymes, and result from structural similarities between substrate and inhibitors

71 demonstrate that the decline of sequence and structural similarities between such orthologs significa

72 In addition, the structural similarities between the compounds within a d

73 Finally, we observed structural similarities between the PEAK1 SHED region an

74 Despite the structural similarities between the two classes of compo

75 The notable structural similarities between the two lobes of comet 6

76 However, high structural similarities between the wild-type and mutant

77 The unique structural similarities between these two enzymes make t

78 Structural similarities between TOP2 isoforms challenge

79 from human, fly and worm, and we demonstrate structural similarities between transcription start site

80 We found remarkable sequence and structural similarities between TssA1 and gp6 C-termini,

81 Informatic analyses revealed structural similarities between VPg and the human kinesi

82 licity of the synthetic methodology, and the structural similarity between [Fe(34) ], bulk iron oxide

83 t to provide comprehensive information about structural similarity between a pair of nodes.

84 nk between AD and T2D might originate from a structural similarity between aggregates of Abeta and hI

85 These data suggest a strong structural similarity between bacterial and eukaryotic v

86 Despite the structural similarity between C4a and well-described ana

87 , we develop a cluster analysis based on the structural similarity between configurations and use it

88 emble for quantifying population overlap and structural similarity between ensembles.

89 Furthermore, structural similarity between Juno and the cholesterol-b

90 Thus, while close structural similarity between PET ligands and drug leads

91 These findings reveal structural similarity between ribosomes in initial selec

92 Hence, despite the structural similarity between the compounds, differences

93 Despite overwhelming structural similarity between the periplasmic domains of

94 However, despite the structural similarity between the tert-butyl and amyl mo

95 its size, and 4) whether there is sufficient structural similarity between the two model samples in e

96 Despite the high structural similarity between the two SH2 domains, we ob

97 We observed a high degree of structural similarity between their backbone atoms (0.96

98 Despite the structural similarity between those and host nucleic aci

99 In line with this structural similarity, biochemical characterization of t

100 Despite the little structural similarity, both receptor types activate simi

101 r two cationic alpha-helical AMPs that share structural similarities but have a ten-fold difference i

102 nosine A2AR and A2BR share many sequence and structural similarities but highly differ in their respo

103 We demonstrate that compound structural similarity can serve as a proxy for toxicity,

104 present Comparison of Hi-C Experiments using Structural Similarity (CHESS), an algorithm for the comp

105 l cycle fingerprint analysis and 3D chemical structural similarity clustering identified unexpected F

106 Although sharing many sequence and structural similarities, CUL4B plays distinct roles in s

107 Despite their very close structural similarity, CxxC/S-type (class I) glutaredoxi

108 ing the first three skip residues share high structural similarity despite their low sequence homolog

109 ed by different proteins/peptides share many structural similarities, despite sometimes large amino a

110 Despite the structural similarity, differences were observed in thei

111 (La, Pr for high and Ce for low) affirm the structural similarities extend beyond the unit cell para

112 ierarchical clustering protocol based on DRP structural similarity, followed by two post-processing s

113 erences and clusters them according to their structural similarities for easy analysis.

114 of the interface, we exploited the predicted structural similarities for human and Tetrahymena thermo

115 nd murine DC subsets has emerged, underlying structural similarities for the DC lineages between thes

116 is of CDR3s of known structure, clustered by structural similarity, helps calibrate the limits of seq

117 Despite high structural similarity, however, contrasting binding mode

118 Protein kinases share significant structural similarity; however, structural features alon

119 "pocket profile method", we use sequence and structural similarities in the binding pockets of human

120 occurs via the VP motif in CRY2, suggesting structural similarities in the VP-binding pockets of COP

121 ablishment, and reactivation in vivo Despite structural similarities in their DNA-binding domains (DB

122 nt than that of torsion angles or of overall structural similarities in virus host tropisms.

123 Despite high sequence conservation and structural similarity in the NES-binding cleft region, (

124 sting because DINCH metabolites and MNP have structural similarities(.)In conclusion, phthalates meta

125 andard deviation] vs 33.74 +/- 3.64), higher structural similarity index (0.92 +/- 0.05 vs 0.93 +/- 0

126 k signal-to-noise ratio (36.3 +/- 3.0), mean structural similarity index (0.98 +/- 0.01), and voxelwi

127 and CS images included reconstruction times, structural similarity index (SSIM) and normalized root-m

128 ourier-based zero padding by calculating the structural similarity index (SSIM) between high-resoluti

129 or Peak Signal to Noise Ratio (PSNR) and the Structural Similarity Index (SSIM) to WBP and SART; even

130 ays to assess transmitted image quality: the structural similarity index (SSIM), a perceptual distort

131 r plots for the first time, specifically the structural similarity index (SSIM), to identify rapid ne

132 ling improved peak signal-to-noise ratio and structural similarity index by 62% (P < .05) and 7.3% (P

133 uding the peak signal-to-noise ratio (PSNR), structural similarity index metric (SSIM), regionwise SU

134 ee aspects: peak signal-to-noise ratio, mean structural similarity index, and visual information fide

135 ror, the peak signal-to-noise ratio, and the structural similarity index, in addition to a joint hist

136 onstructed image quality, quantified using a structural similarity index.

137 s the highest peak signal-to-noise ratio and structural similarity index.

138 t biological truth using immunostaining mean structural similarity indexes (SSIM) of 0.925 and 0.920

139 Structural similarities indicate that mosquito and sand

140 However, their structural similarities is an amazing example of converg

141 gions of the polypeptide, whereas the global structural similarity is captured by the root mean-squar

142 ource, the ability to search the database by structural similarity is essential.

143 This structural similarity is supported by sequence compariso

144 tations mainly to 'Inferred from Sequence or structural Similarity (ISS)', probably reflecting an err

145 Despite the structural similarity, it is not known whether the PAS d

146 Despite sharing significant structural similarity, JJC8-088 was more cocaine-like, i

147 es enzymatic transformations with metabolite structural similarity, mass spectral similarity and empi

148 High structural similarity may suggest that a link between tw

149 binding pharmacophores (MBPs), metalloenzyme structural similarity (MeSIM) and ligand chemical simila

150 each cluster, (vi) construct and visualize a structural similarity network of compounds providing a s

151 h a reference set of compounds into a single structural similarity network providing the opportunity

152 We calculated structural similarity networks in each participant and h

153 Nodal degree of structural similarity networks was computed for each sub

154 NA self-assembly because of the chemical and structural similarities of DNA and RNA.

155 X-ray scattering (SAXS) studies confirm the structural similarities of TAPBPR with tapasin.

156 The brevity of the route and the structural similarity of a key intermediate to many pote

157 Herein, starting from the structural similarity of a potent G4 ligand previously d

158 Regardless of the structural similarity of both the organosulfur compounds

159 The striking structural similarity of CblD to CblC, believed to be co

160 Predicted overall structural similarity of Herp to the ubiquitin-proteasom

161 ry highlight the contrast between the global structural similarity of homologous transporters and the

162 On the basis of the structural similarity of isoprostanoid moieties that are

163 Moreover, due to the structural similarity of KuQuinones with camptothecin (C

164 On the basis of the structural similarity of our previous 5-HT2C agonists wi

165 Considering close structural similarity of sphingosine and FTY720 we inves

166 ectroscopy, the results of which support the structural similarity of the complexes.

167 exes, determined to 1.6 A, reveal remarkable structural similarity of the dimer interface with 3CL(pr

168 typical protein kinases have highlighted the structural similarity of the kinase superfamily despite

169 rol probe to NPC proteins, demonstrating the structural similarity of the probe to cholesterol.

170 electrically driven CE is determined by the structural similarity of the sulfur sublattices between

171 ecretory processes in different tissues, the structural similarity of the three isoforms makes this d

172 The structural similarity of the two parental subgenomes mig

173 but the cause has remained elusive given the structural similarity of the two tandem domains.

174 several Fagales trees based on sequence and structural similarity of their allergen proteins.

175 otential parent compounds and TPs, while the structural similarity of these pairs hypothesized by MS/

176 t be rationally designed because of the high structural similarity of these two subunits.

177 plasma membranes remain ill-defined, but the structural similarity of water and NH3 has pointed to th

178 Despite their structural similarities, only Xlf(-/-) cells, but not Pa

179 grammatical inferences overwhelmingly favor structural similarity over preservation of superficial o

180 ity 4 (Ctf4) based on phylogenetic analysis, structural similarities, physical interaction with the C

181 f cell wall binding profiles, which based on structural similarity prediction by BLASTp, can possibly

182 as a measure of a random network's internal structural similarity, ranking networks on a continuous

183 dicated that both processes were governed by structural similarity rules.

184 Therefore, despite the high degree of structural similarity, RUNX1B and RUNX1C isoforms have d

185 alignment is then determined by the maximum structural similarity score, GS-score, which is size-ind

186 Amino acid sequence and predicted structural similarity searches using the nonrepeat regio

187 identify more HPIs than sequence or complete structural similarity since it appears more common than

188 rror, peak signal-to-noise ratio (PSNR), and structural similarity (SSIM) index metrics.

189 Despite this structural similarity, substantial differences in the di

190 Structural similarities suggest this pathway follows a b

191 these loops evolved independently, but their structural similarity suggests a common ancestor.

192 This structural similarity suggests that the putative PirAB(v

193 Based on a structural similarity survey of other inhibitors with th

194 Surprisingly, despite this structural similarity, the affinity of Cul3-NTD for A55B

195 Notably, despite their structural similarities they exert diverse modulation on

196 Despite structural similarity, they respond to distinct ligands

197 erodimeric proteins on its surface that have structural similarities to a protein crucial for invasio

198 onal substrate for these maps share distinct structural similarities to a unique extent in decapods,

199 Despite ticagrelor's structural similarities to adenosine, the Fab is highly

200 s placed on designing polymers which have no structural similarities to antifreeze proteins but repro

201 that, despite low sequence identity, M11 has structural similarities to Bcl-xL, Bcl-2, and Bcl-w.

202 nce of double bonds, the [n]cumulenes, share structural similarities to both of their conjugated rela

203 biosynthesis of ergothioneine in EgtB shows structural similarities to cysteine dioxygenase which tr

204 y, multiple dynein arm assembly factors show structural similarities to either Tah1 or Pih1, the othe

205 single to double strand boundaries that have structural similarities to hairpins and fixed 5' and 3'

206 In contrast, HdeB, which has high structural similarities to HdeA, shows negligible chaper

207 Taken together, despite structural similarities to MDMA, exposure to methylone o

208 croorganisms cometabolize ammonia due to its structural similarities to methane.

209 ropose an extended DPS model that emphasizes structural similarities to pseudostratified neuroepithel

210 ression patterns of four other peptides with structural similarities to studied venom components and

211 didate 2), a Plasmodium berghei protein with structural similarities to subtilisin-like proteins.

212 -to-noise ratio of 31 +/- 9 and demonstrated structural similarities to the gray matter distribution

213 ferent regions of Izumo1 display significant structural similarities to two proteins expressed by the

214 Despite structural similarities to well-known ligand classes suc

215 The device design has a high degree of structural similarity to a human eye with the potential

216 an accessory N-terminal domain that has high structural similarity to a recently discovered motif pre

217 In spite of its structural similarity to acetylcholine, there are no oth

218 ogue from M. tuberculosis and generally high structural similarity to alpha/beta-hydrolase EHs.

219 Cr-UVR8 shares sequence and structural similarity to Arabidopsis thaliana UVR8, has

220 e deiodinase 3 (Dio3), which reveals a close structural similarity to atypical 2-Cys peroxiredoxin(s)

221 main in the BF1687 protein, show significant structural similarity to bacterial pore-forming toxins.

222 The new materials bear close structural similarity to BODIPYs but differ significantl

223 s of fundamental importance because of their structural similarity to cell wall-modifying enzymes suc

224 The C domain of ParB harbors structural similarity to CenpA, which dictates eukaryoti

225 similarity to geranic acid and cations with structural similarity to choline at a ratio of 1:2.

226 Based on Tk-AMP-X2 structural similarity to cone snail and scorpion potassi

227 rom C. trachomatis (PDB 6MAB) displays close structural similarity to DctB from Vibrio and Sinorhizob

228 rget the thyroid system, likely due to their structural similarity to endogenous thyroid hormones.

229 make a variety of related diterpenes, whose structural similarity to ent-kaurene makes them potentia

230 of a two-layered (4 + 3) beta-sandwich with structural similarity to fibronectin type 3 domains.

231 While individual MUB domains showed structural similarity to fimbrial proteins from Gram-pos

232 nd bioinformatics predictions that suggested structural similarity to folliculin, the Birt-Hogg-Dube

233 o-beta-d-arabinofuranosylcytosine) has close structural similarity to gemcitabine and thus offers the

234 iants of CAGE are prepared using anions with structural similarity to geranic acid and cations with s

235 Because of its structural similarity to glucose, genetic studies of 1,5

236 ound to the host receptor CD4, which reveals structural similarity to HIV-1 gp120 despite divergence

237 ring of the optimized conformations based on structural similarity to identify chemically unique conf

238 ata show that a microbial metabolite with no structural similarity to known serotonergic agonists pot

239 eptide (named GrCLE1-1Hyp4,7g) with striking structural similarity to mature plant CLE peptides.

240 a unique class 27 myosin, TgMyoF, which has structural similarity to myosin V, the prototypical carg

241 lethanolamide and cardanolethanolamide, with structural similarity to NAEs and characterized their ef

242 The prepared microwebs have structural similarity to NETs at the nanometer to microm

243 nd that Pseudomonas FliD exhibits unexpected structural similarity to other flagellar proteins at the

244 ause bestrophin channels have no sequence or structural similarity to other ion channels, the molecul

245 The overall fold of FhGST-S1 shows high structural similarity to other Sigma class GSTs.

246 sin, which is a nonapeptide with substantial structural similarity to oxytocin, did not alter ethanol

247 is a globular beta-sandwich protein showing structural similarity to Phl p 2 and the Phl p 1-C-termi

248 to crystallize a DNA-bound complex; however, structural similarity to previously crystallized restric

249 natural products being published today bear structural similarity to previously published compounds,

250 CTC1 has stronger structural similarity to Replication Protein A than the

251 is indicated that CT009 shares high level of structural similarity to RodZ, revealing the conserved o

252 balt(II) bis(pivalate) complexes, which bear structural similarity to state-of-the-art ruthenium(II)

253 sinosteroids (BRs), a group of steroids with structural similarity to steroid hormones of mammals.

254 d Drug Administration owing, in part, to its structural similarity to telithromycin.

255 d Drug Administration owing, in part, to its structural similarity to telithromycin.

256 structure determined, shows a high degree of structural similarity to that of human ADS lyase.

257 Spen binds directly to ERV RNAs that show structural similarity to the A-repeat of Xist, a region

258 Although MraZ has structural similarity to the AbrB transition state regul

259 , a not unexpected outcome given their close structural similarity to the antiandrogenic drug nilutam

260 al targets for drug repurposing based on sub-structural similarity to the binding interfaces of known

261 Since Diprovocim bears no structural similarity to the canonical lipopeptide ligan

262 sion of this mitochondrial protease that has structural similarity to the cytoplasmic proteosome is i

263 Notably, the pyridine synthases show structural similarity to the elimination domain of lanth

264 lly synthesized peptidomimetics that bear no structural similarity to the established TLR4 ligand, li

265 Despite high sequence (48% identity) and structural similarity to the GRE-type glycerol dehydrata

266 dues, and a portion of the active site shows structural similarity to the GTP-binding site of MoaA, s

267 d consists of a four-alpha-helix bundle with structural similarity to the high mobility group box, a

268 This enzyme shows a strong structural similarity to the human phosphatases of regen

269 conserved region (region IX) with predicted structural similarity to the human topoisomerase I core

270 Cryo-EM of the NTD dimer revealed a structural similarity to the scaffold domain of TBK1, su

271 DPUP has close structural similarity to the severe acute respiratory sy

272 2 reveals that the protein shares intriguing structural similarity to ToxA from the wheat pathogen Py

273 Domain A, which exhibits structural similarity to tRNA, appears to be an essentia

274 The high sequence and structural similarity, together with the different toxic

275 Despite structural similarities, we demonstrate that the electro

276 Drawing parallels based on structural similarity, we postulated that AIF1L might co

277 Considering this structural similarity, we propose that eukaryal RNA inte

278 They share significant sequence and structural similarities, which results in cross-recognit

279 el, and the additional use of sequence-based structural similarity, which uses similarity to sequence

280 domains through a disulfide bond, revealing structural similarities with ADP regulation in the human

281 s further study, ORF52 shares functional and structural similarities with alphaherpesvirus VP22, unde

282 estry, many components of mitochondria share structural similarities with bacteria.

283 llergy with other disinfectants, which share structural similarities with CHX like polyhexanide (poly

284 Amphomycin and MX-2401 share structural similarities with daptomycin, but unlike dapt

285 lia, which exhibits significant sequence and structural similarities with human EZH2, catalyzes methy

286 Due to widespread human exposure, and structural similarities with known endocrine disruptors,

287 th microtubule (MT)-stabilizing activity and structural similarities with known NSAIDs, we conducted

288 In its cyclic form, it shares structural similarities with plant cyclotides that also

289 a nanoparticles by thermolysis, due to their structural similarities with silica materials.

290 Together, WarA and WarB have structural similarities with the bifunctional Escherichi

291 and comparative analyses reveal sequence and structural similarities with the distant Acidobacteria L

292 Despite some structural similarities with well-known aza-BODIPYs, the

293 The high levels of structural similarity with cyanobacterial Fds and reacti

294 PAXX is the newest NHEJ factor, which shares structural similarity with known NHEJ factors-XRCC4 and

295 rich alpha1-helix in endostatin-which shares structural similarity with noncanonical nuclear receptor

296 ions of GM-CSF and IL-2, without sharing any structural similarity with the cytokine receptors.

297 ed within 150 min by taking advantage of its structural similarity with the parent lamellar precursor

298 nces of single-atom catalysts (SACs) and the structural similarity with their molecular analogs, sugg

299 a-RalGAPbeta heterodimer shares sequence and structural similarity with Tsc1-Tsc2.

300 ajor Arctic conformers has surprisingly high structural similarity with wild-type Abeta42.