ライフサイエンスコーパス: stymy

1 ding of cortico-striatal brain circuitry has stymied a molecular mechanistic understanding of this di

2 lopments addressing problems that previously stymied accurate effect estimation, the solution of whic

3 o respond to changes in selection, therefore stymying adaptation to further environmental change.

4 ion-level monitoring in tropical forests has stymied assessment of biodiversity outcomes, such as the

5 The presumed broad tropism of poxviruses has stymied attempts to identify both the cellular receptor(

6 The large size of poxvirus genomes has stymied attempts to identify determinants recognized by

7 But, a computational hurdle has stymied attempts to measure large-scale information inte

8 explain variation in urban tolerance, which stymies attempts at a generalizable predictive framework

9 ation derived from cancer patients worldwide stymies basic research and clinical decisions.

10 al of short interfering RNA (siRNA) has been stymied by a key obstacle-safe delivery to specified tar

11 uctions and modeling with SPDs, however, are stymied by a lack of accepted methods for model fitting,

12 oad/use, iCLOTS addresses a need for a field stymied by a lack of analytical tools for innovative, ph

13 ajor cause of cirrhosis and cancer, has been stymied by a lack of animal models.

14 cal functions of individual lipids have been stymied by a lack of approaches for controlled modulatio

15 s C virus (HCV; human hepacivirus) have been stymied by a lack of small animal models.

16 pes, including those linked via K6, has been stymied by a lack of specificity among the implicated re

17 But this quest has been stymied by a lack of validated biological markers for ch

18 odern electronic systems, but they have been stymied by a limited understanding of the microwave, sys

19 ess, practically, viscous streaming has been stymied by a narrow set of achievable flow topologies, l

20 health benefits of HAP mitigation have been stymied by an inability to lower emissions to target lev

21 adversarial collaborative research has been stymied by an overly restrictive concern with the falsif

22 hange in a warming Arctic(8) has so far been stymied by conflicting observations about whether permaf

23 Recognizing that progress is stymied by dielectric loss, we start with a system with

24 iscovery approaches to tackle PPIs are often stymied by difficulties in the production of stable, unl

25 erage insights from the urban past have been stymied by disciplinary silos and entrenched misconcepti

26 metabolic changes therapeutically have been stymied by drug toxicity and tumour cell plasticity.

27 but progress in this field has been slow and stymied by experimental limitations.

28 ial distribution of step-pool units has been stymied by experimental rill-bed profiles exhibiting irr

29 es targeting HIV-1's gp160 spike protein are stymied by high viral mutation rates and structural chic

30 Clinical biomarker development has been stymied by inaccurate protein quantification from mass s

31 owever, the use of NicA2 in this capacity is stymied by its dismal O(2)-dependent activity.

32 action of WIN site inhibitors, however, are stymied by its many functions in the nucleus, and a lack

33 Uptake of this new technology is stymied by its single user orientation and its prerequis

34 nfrared (NIR) region, but their use has been stymied by lack of access to stable, synthetically malle

35 However, this potential has been stymied by lack of approaches for molecular profiling of

36 However, inhibitor development has been stymied by limited mechanistic details for the enzyme, p

37 to improve cobalt oxide's activity have been stymied by limited mechanistic understanding that stems

38 olerance, but translation to humans has been stymied by low abundance of primary human beige adipocyt

39 n of CaMKII antagonists into humans has been stymied by low potency, toxicity, and an enduring concer

40 ture contributes to these functions has been stymied by our inability to produce this glycan as a hom

41 Improvement in outcomes has been stymied by poor understanding of the genetics and molecu

42 So far, these efforts have been stymied by qubit inhomogeneities, low device yield and c

43 ental studies and practical applications are stymied by sample polydispersity.

44 esponding differences in phenotype have been stymied by several basic technical challenges.

45 Efforts to understand this have been stymied by severe technical limitations due to substanti

46 ssure; so far, direct observations have been stymied by technical and thermal noise.

47 modes of signal transduction has often been stymied by technical challenges.

48 Progress is stymied by technical difficulties in manipulating the mi

49 e development of selective agonists has been stymied by the alpha7 receptor's intrinsically low proba

50 the path toward real-world adoption has been stymied by the challenge of evaluating the clinical qual

51 contacts lutropin receptors (LHR) have been stymied by the complex structure of the hormone and the

52 Studies have been stymied by the difficulty of assembling mutidecadal habi

53 ns of spatial navigation in humans have been stymied by the difficulty of recording during free explo

54 uperresolution fluorescence and EM have been stymied by the divergent and incompatible sample prepara

55 al measurements non-invasively from video is stymied by the fact that it is a hard computational prob

56 However, multisample SV analysis has been stymied by the fundamental difficulties of SV calling, e

57 artificial photosynthesis--has largely been stymied by the impractically high overpotentials necessa

58 Ironically, such efforts are stymied by the inherent biocompatibility and recalcitran

59 This progress is stymied by the interactions between samples and the many

60 tion of their genotypic differences has been stymied by the lack of a unifying genomic resource for C

61 ore targeted, HB-specific therapies has been stymied by the lack of fundamental knowledge about HB bi

62 mage and spread of chytrid disease have been stymied by the lack of knowledge about basic chytrid bio

63 nization at the nanoscale, however, has been stymied by the lack of practical means of cell analysis

64 sts to use such information is significantly stymied by the lack of publicly available algorithms and

65 Even the most innovative research is stymied by the lack of representative samples of the pop

66 ns in the thousands of years since have been stymied by the large interindividual variability in drug

67 ea in electronics development, but are often stymied by the large minimum feature size.

68 t analysis of the endogenous kinase has been stymied by the low levels of protein present in cells an

69 rts targeting the SH2 domains have long been stymied by the poor drug-like properties of phosphate an

70 tween apo-HasAp and human methemoglobin were stymied by the rapid heme capture by the hemophore.

71 technology to analyzing genomic DNA has been stymied by the sequence complexity of the entire human g

72 velopment of efficacious treatments has been stymied by the unknown aetiology, although recent advanc

73 ress in developing these inhibitors has been stymied by their CD4-agonist properties, an unfavorable

74 freedom, but measurements to date have been stymied by their sensitivity to only one of these compon

75 ith such an electronic ground state has been stymied by these molecules' tendency to distort into str

76 ever, traditional model-based approaches are stymied by uncertainty surrounding the underlying driver

77 ver, a paucity of existing AB cell lines has stymied clinical translation.

78 ogy network that link unrelated families and stymy clustering algorithms.

79 d arc magmatism above subduction zones, have stymied consensus on what parental magmas crystallized t

80 Poor access to diagnosis stymies control of visceral leishmaniasis (VL).

81 onal expansion of the druggable proteome and stymies critical advancements in the field, such as tiss

82 mall energy gaps and limited tunability have stymied definitive experimental probes of their non-Abel

83 ariability and similarity to host cells have stymied development of broad anti-cancer therapeutics.

84 erstanding of environmental risk factors has stymied development of prevention strategies.

85 lution of the long-standing issues that have stymied development of the transfer model now make it po

86 t progress toward practical systems has been stymied due to a lack of materials and devices with the

87 f traditional muscarinic activators has been stymied due to pan-receptor activation, muscarinic recep

88 However, its use in genomics is stymied due to the difficulty in storing large-scale dat

89 pproaches to study dinoflagellates are often stymied due to their large, multi-gigabase genomes.

90 been a priority, yet such attempts have been stymied due to their low abundance and the rich cellular

91 understanding of these interactions has been stymied due to various hurdles in studying the genetics

92 sagreements over what should be removed have stymied efforts to deal with misinformation in the Unite

93 This discrepancy has stymied efforts to design the complex temperature, seque

94 bstances, including solvents, heretofore has stymied efforts to develop robust methods to characteriz

95 Deficiencies in time control that have long stymied efforts to establish orbital effects on deglacia

96 or human-associated viruses has historically stymied efforts to interrogate the impact of the virome

97 A high content of disorder in HSPB5 has stymied efforts to uncover how its structure gives rise

98 epository infrastructure throughout Mongolia stymies efforts to study or respond to large-scale envir

99 but the unreliability of IL-15 detection has stymied exploration of IL-15 regulation in vivo.

100 Addressing these questions is stymied, however, by 1) a lack of multiple comparable EV

101 Progress in these areas is stymied, however, by a lack of accessible knowledge pert

102 xhibits dystonic-like twisting movements has stymied identification of the cellular and molecular und

103 netic dissection of domain function has been stymied in mouse because there are 24 related and partia

104 se transport into the cells, which, in turn, stymies mitochondrial respiration.

105 Mutation of tyrosine 213 of Fyn stymied nuclear export, suggesting that tyrosine phospho

106 nfer that sexual conflict may be effectively stymied or non-existent within these taxa.

107 e born in mind when designing a strategy for stymying or stimulating fibril nucleation.

108 tional mobility of acyl carrier protein have stymied previous attempts to visualize structurally acyl

109 ze-based limitations on experimentation have stymied progress by limiting the speed and scale of thes

110 An overemphasis on amyloid has stymied progress on the disease, alleges a neuroscientis

111 This technical hurdle has stymied progress toward understanding persistence.

112 he lack of machine-learnable representations stymies progress toward structure-property relationships

113 e zero-valent molecular vanadium precursors, stymying research on this important material.

114 selection may be sufficient to suppress and stymy sexual conflict if it acts orthogonal to sexual se

115 minating the exponential complexity that has stymied simulation of correlated quantum systems on high

116 the multicellularity of the intact islet has stymied specific experimental approaches-particularly in

117 th the etiology and symptoms of SPG4-HSP has stymied the development of effective therapies for the d

118 This has stymied the development of more effective therapeutic ap

119 This has stymied the development of pharmacological interventions

120 This study reveals how memory effects stymied the locomotion of a diversity of snakes in our p

121 lar systems, but throughput limitations have stymied the scalable identification of fragment-protein

122 olutions to long-standing problems that have stymied the search for a prebiotic synthesis of nucleic

123 t a paucity of scalable bottom-up approaches stymies the harnessing of smart tissues' biological, mec

124 The rarity of the disease has stymied therapeutic development.

125 on SSB taxes and their designs, however, has stymied understanding of current practice in SSB taxes.

126 e field, an archaic regulatory framework has stymied US clinical practice.

127 n these settings, true joint analysis can be stymied using conventional statistical methods, which re

128 urvival signals in melanoma cells and can be stymied using inhibitory mAbs.

129 e immune response, characteristics that have stymied vaccine development and cause people living in e

130 Development of an RSV vaccine was stymied when a clinical trial using a formalin-inactivat