ライフサイエンスコーパス: subcellular location

1 ellular behavior (i.e. aggregation state and subcellular location).

2 is of protein-protein interactions and their subcellular location.

3 is regulated in large part by control of its subcellular location.

4 unction of some enzymes is governed by their subcellular location.

5 ent properties to simulate mixed patterns of subcellular location.

6 l peptidoglycan synthase activity at a given subcellular location.

7 e effects of mild oxidative injury vary with subcellular location.

8 ocesses in which they play a role, and their subcellular location.

9 question of how PTPMEG2 is targeted to this subcellular location.

10 we investigated its tissue distribution and subcellular location.

11 nteraction module to dock CikA at a specific subcellular location.

12 ryl hydrocarbon receptor (AHR) stability and subcellular location.

13 ryl hydrocarbon receptor (AHR) stability and subcellular location.

14 unique functions of Agap2 determined by its subcellular location.

15 ive abundance of these PTMs as a function of subcellular location.

16 enzymes regulate this process at a distinct subcellular location.

17 ncluding it is the major or only Grx in this subcellular location.

18 econd messenger produced at several discrete subcellular locations.

19 ave different tissue expression patterns and subcellular locations.

20 fined understanding of signaling at distinct subcellular locations.

21 ular motors transport organelles to specific subcellular locations.

22 o transport diverse cargo to the appropriate subcellular locations.

23 chinery to express and transport proteins to subcellular locations.

24 n of different GTPase effectors in different subcellular locations.

25 um/calmodulin kinase II isoforms to specific subcellular locations.

26 s dynamic clusters at both polar and lateral subcellular locations.

27 striction of signaling complexes to discreet subcellular locations.

28 d with each other, but are found in distinct subcellular locations.

29 ocalization to and delocalization from these subcellular locations.

30 different sets of intermediates at different subcellular locations.

31 lasm without being constrained to particular subcellular locations.

32 g ABA receptors for degradation in different subcellular locations.

33 nct ubiquitin E3 ligase complex at different subcellular locations.

34 nstructed two more datasets of nine and five subcellular locations.

35 can be differentially regulated at different subcellular locations.

36 egmented them into 12 classes based on their subcellular locations.

37 rt and delivery of selected MBOs to discrete subcellular locations.

38 several ATP-fueled proteases occupy distinct subcellular locations.

39 pport the interaction with RNAs in different subcellular locations.

40 t at, or move between, two or more different subcellular locations.

41 support interactions with RNAs in different subcellular locations.

42 ific protein functional domains in different subcellular locations.

43 de channel/transporter family have different subcellular locations.

44 lated trafficking of mitochondria to defined subcellular locations.

45 n be activated by growth factors at distinct subcellular locations.

46 d compositional differences across different subcellular locations.

47 teins (AKAPs) bind and target PKA to various subcellular locations.

48 restrain kinase inhibitor drugs at distinct subcellular locations.

49 ns', may simultaneously occur in two or more subcellular locations.

50 clear how this complex is regulated at other subcellular locations.

51 activity is temporally regulated at specific subcellular locations.

52 independent of each other, to their separate subcellular locations.

53 ls to nucleus and becomes dispersed in other subcellular locations.

54 atures, protein aggregates form in different subcellular locations.

55 ctional domains, or by acquiring alternative subcellular locations.

56 athways that shape APA profiles in different subcellular locations.

57 dy-state dynamics of proteins and unexpected subcellular locations.

58 the local interaction network organized into subcellular locations.

59 amics of eisosome core proteins at different subcellular locations.

60 aling pathway can be activated from multiple subcellular locations.

61 es global analysis of translation in defined subcellular locations.

62 Production of H(2) O(2) : enzymes and subcellular locations 1200 V.

63 ish receptor-mediated signaling at different subcellular locations, a phenomenon known as spatial sen

64 early endosomes or mitochondria changes the subcellular location and availability of EPS15.

65 found in homogenized plant tissues, but its subcellular location and availability to plant microbes

66 with a role in pH homeostasis, though their subcellular location and biological roles in plants are

67 While much is known about the subcellular location and biophysical properties of condu

68 Their specific subcellular location and differential expression pattern

69 were used to examine the effects of antigen subcellular location and expression level on the develop

70 ctive molecular hierarchy depending on their subcellular location and extracellular stimuli.

71 -terminal sequence elements that promote Chp subcellular location and function expand the complexity

72 The subcellular location and function of one of these member

73 However, little is known regarding the subcellular location and function of the majority of the

74 n Cdc42, suggesting potential differences in subcellular location and function.

75 xpressed the PPE proteins can alter both the subcellular location and level of accumulation of the up

76 We investigated the subcellular location and myristoylation of AtCPK5, a mem

77 n and dephosphorylation of Pah1 regulate its subcellular location and phosphatidate phosphatase activ

78 -Pick C1, was characterized to determine its subcellular location and potential function(s).

79 e interaction of PKA with AKAPs disrupts its subcellular location and prevents LTP in the hippocampus

80 This study examines the subcellular location and relationship with prognostic fa

81 resent studies were undertaken to define the subcellular location and role of RyR in the control of s

82 fusion expression can have a bold effect on subcellular location and that chromosomal, intraoperon e

83 ulation of molecules within neurons, but the subcellular location and the cellular impact are often u

84 li K-12 as well as information regarding its subcellular location and the genetic loci involved in it

85 To investigate the subcellular location and the mechanism of ecto-nucleotid

86 en observed to localize to several different subcellular locations and cellular redox conditions vary

87 ly of dozens of heterotrimers with different subcellular locations and cellular substrates dictated b

88 ns and in gene regulation, we analyzed their subcellular locations and DNA-affinities.

89 The apparatus assembled in discrete subcellular locations and exported Hcp1, a hexameric pro

90 f CAAX signal modifications in dictating the subcellular locations and functions of the Rho GTPase fa

91 2 PDI genes, but little is known about their subcellular locations and functions.

92 between many types of proteins in different subcellular locations and in different cell types and or

93 essed protein displays at least two distinct subcellular locations and related functions.

94 ding proteins that it predicts share similar subcellular locations and residue charge profiles with t

95 oach to determine Cdc42 activity at specific subcellular locations and reveals new regulatory princip

96 l proteins appear more frequently in certain subcellular locations and their evolution more conservat

97 udied for many years, but annotating protein subcellular locations and understanding variation of the

98 peptides from source proteins of almost all subcellular locations and were involved in various cellu

99 t particular Gbetagamma subunits to specific subcellular locations and/or macromolecular complexes in

100 en identified that direct PP1 to a number of subcellular locations and/or substrates, no targeting su

101 molecules and its implication for function, subcellular location, and half-life of proteins.

102 ttern of the dibenzylcyclooctynes influences subcellular location, and in particular it has been show

103 otential varies, depending on energy demand, subcellular location, and morphology and is commonly use

104 cycle stage at which proteins are expressed, subcellular location, and other proteomic features.

105 ntly more likely to be found within the same subcellular location, and significantly less likely to b

106 protomers are too weak to directly influence subcellular location, and that mechanisms that move thes

107 timate the fractions of protein in different subcellular locations, and can help to quantify the chan

108 lipoprotein that is able to occupy distinct subcellular locations, and challenges models in which th

109 r regulation, establish their biogenesis and subcellular locations, and explore their functionality.

110 ycosylation between individuals, cell types, subcellular locations, and pathophysiological conditions

111 ich engulf portions of cytoplasm at specific subcellular locations, and their subsequent maturation i

112 ctors of survival and death are in different subcellular locations, and thus depend on the spatial ch

113 to modulate betagamma signaling at specific subcellular locations, and we demonstrate novel cargo se

114 eening suffer significantly from the lack of subcellular location annotations for bioimages from canc

115 attachment to membranes and rafts, and their subcellular locations are poorly understood; live prion

116 specificity of sgk1 function; however, which subcellular locations are required for sgk1-regulated EN

117 ematic and comprehensive analysis of protein subcellular location as a critical part of proteomics ('

118 in to promote protein associations or direct subcellular location, as seen in other UBA-containing pr

119 ation of ETR2 does not require exit from its subcellular location at the endoplasmic reticulum.

120 t is highly desirable to predict a protein's subcellular locations automatically from its sequence.

121 SVM modules were trained to predict the subcellular location based on amino acid composition and

122 rial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, r

123 Cofactors can target PP1 to substrates or subcellular locations, but it remains unclear how they m

124 of the type IV apparatus, we determined its subcellular location by immunofluorescence microscopy.

125 roteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) t

126 es these excitotoxic Tat effects at the same subcellular locations by mobilizing additional [Ca(2+)]i

127 cytometric analysis of cells and proteins in subcellular locations by use of multiplexed antibody sta

128 llows the targeting of proteins to different subcellular locations by use of nanobody-fusion proteins

129 se proteins were classified into 22 distinct subcellular location categories by visual examination.

130 ng of Gbetagamma to the Golgi, but not other subcellular locations, causes phospholipase C- and prote

131 We validate our framework on protein subcellular location classification, and show that the c

132 ructural evidence that in the VTA, M5R has a subcellular location conducive to major involvement in p

133 print designs this kinase to be regulated by subcellular location-dependent interactions with inhibit

134 bryonic kidney 293 (HEK293) cells, and their subcellular locations determined by confocal fluorescenc

135 sult in improved accuracy and sensitivity of subcellular location difference detection.

136 VA polymerization only occurs at the correct subcellular location during spore morphogenesis.

137 Spatial restriction of mRNA to distinct subcellular locations enables local regulation and synth

138 ano, we achieve RTK activation at a specific subcellular location even with whole-cell illumination,

139 The sorting of RNA molecules to subcellular locations facilitates the activity of spatia

140 s the destruction complex at the appropriate subcellular location, facilitating betacat destruction.

141 ce of mRNA translational repression and mRNA subcellular location for protein expression during B lym

142 G protein biology and redefine the ERES as a subcellular location for signal integration during morph

143 cellular transport of a 7TMR to its obligate subcellular location for signaling.

144 However, the subcellular location for SOCE in muscle fibers has not b

145 nnate immune signaling receptors that sample subcellular locations for foreign molecular structures,

146 vious systems for automated determination of subcellular location from microscope images has been don

147 he cAMP-dependent protein kinase to distinct subcellular locations, function as molecular scaffolds m

148 The alteration of phytochromes' subcellular location functions as a major regulatory mec

149 ins in Escherichia coli localize to specific subcellular locations, fundamental questions remain abou

150 r preferential NMDAR inhibition depending on subcellular location has not been investigated systemati

151 infected neurons and the protein's specific subcellular location have not been determined.

152 s responsible for callose deposition in this subcellular location have not been identified.

153 same score and ranking for several different subcellular locations, implying that they may simultaneo

154 rat liver microsomes, and rate of uptake and subcellular location in A549 and MCF-7 cells.

155 GH, we modulated its level of expression and subcellular location in Arabidopsis plants and tomato fr

156 mbrane domains, consistent with their unique subcellular location in the PG.

157 tilbenoid substrates, and we confirmed their subcellular location in the plastid by fluorescence micr

158 To ascertain the importance of eNOS subcellular location in this process, we used ECV-304 ce

159 of proteins are known to reside at specific subcellular locations in bacterial cells.

160 he determination of molecular hierarchies at subcellular locations in live cells.

161 ae were difficult to detect, we tested their subcellular locations in Physcomitrella patens transform

162 predict proteins targeted to nine different subcellular locations in the eukaryotic animal species.

163 es have implicated restricted and surprising subcellular locations in which miRNA biogenesis or activ

164 ptors are targeted by ubiquitin at different subcellular locations, in which the complexity of the AB

165 acylation of protein plays a pivotal role in subcellular location including targeting to caveolae.

166 portantly, antigens were identified from all subcellular locations, including 18 integral membrane pr

167 those genes are compartmentalized in various subcellular locations, including cytosol, nucleus, vacuo

168 re coexpressed in the same cell had separate subcellular locations, indicating that Che2 proteins do

169 To address whether an antigen's subcellular location influences the nature and magnitude

170 rom the Human Protein Atlas as the source of subcellular location information, and built classificati

171 Subcellular location is an important attribute of protei

172 ng the amount of protein distributed in each subcellular location is essential for quantitative under

173 K-Ras signaling specificity by altering its subcellular location is presented by Bivona et al.

174 onent of the mSin3 corepressor complex whose subcellular location is regulated by PML.

175 Trafficking between these subcellular locations is a regulated dynamic process.

176 uggest that trafficking of LANA to different subcellular locations is a regulated phenomenon, which a

177 ther enzyme specialization occurs in defined subcellular locations is unclear.

178 cified single cell among many, or a specific subcellular location, is still a largely unmet challenge

179 Furthermore, prediction of protein subcellular location not only should be a guiding role i

180 e describe the phylogeny, ultrastructure and subcellular location of 'Candidatus Adiutrix intracellul

181 from 11 studies using MetaMass, mapping the subcellular location of 5,970 proteins.

182 Knowledge of the subcellular location of a protein is crucial for underst

183 r role in drug resistance, we determined the subcellular location of ABCB6.

184 o accurately recapitulate the efficiency and subcellular location of arenavirus GPC processing.

185 The subcellular location of B. pseudomallei within infected

186 eal that not only the amplitude but also the subcellular location of conventional PKC signaling can b

187 Future studies are required to determine the subcellular location of each ACSL and ACSVL isoform and

188 ctions of these gene families, we report the subcellular location of each protein.

189 The subcellular location of enhanced green fluorescent prote

190 on of T cell proliferation by regulating the subcellular location of FoxO1 and FoxO3a, two Class O Fo

191 ectron microscopy were used to determine the subcellular location of FRalpha and PCFT in primary Mull

192 ar basis for this difference we compared the subcellular location of GFP fusions to the 126-kDa prote

193 Excess light regulates both the subcellular location of HSFA1D and its biochemical prope

194 We also visualized the subcellular location of ICEBs1.

195 The finding that the subcellular location of initiation sites and protein mic

196 racellular fluorescence NO probes to map the subcellular location of iNOS and NO under various condit

197 ons provide a strong correlation between the subcellular location of mHTT, disruption of the nucleus,

198 experiments were performed to determine the subcellular location of MKK6, P-p38, and MAPKAPK2 (MK2).

199 Subcellular location of NA-TLRs is a key determinant in

200 alized to the cytoplasm, indicating that the subcellular location of NAD production is not crucial fo

201 reement regarding the potential function and subcellular location of Niemann-Pick C1-like 1 protein h

202 ediated gene transcription, depending on the subcellular location of NMDA receptors, as well as how s

203 play any detectable role in the activity or subcellular location of PKCdelta in cells; in vivo imagi

204 The specific subcellular location of posaconazole and the mechanism b

205 ' are necessary and sufficient to define the subcellular location of processing and to determine to w

206 veloped an automated pipeline to compare the subcellular location of proteins between two sets of imm

207 tifs function as essential regulators of the subcellular location of proteins by interacting with the

208 en used to reversibly manipulate the precise subcellular location of proteins in multicellular organi

209 of proteotoxicity is linked to change in the subcellular location of proteins that cause misfolding d

210 ived from these experiments is mostly of the subcellular location of proteins, and of the participati

211 We investigated the activation and subcellular location of Rac1 in FAK null and FAK reexpre

212 xpression of RD3 in different cell types and subcellular location of retina.

213 lification method to noninvasively image the subcellular location of RNA targets in living cells.

214 To evaluate the influence of Y RNA on the subcellular location of Ro60 during apoptosis and activa

215 Y RNAs regulate the subcellular location of Ro60, since Ro60 is reduced in t

216 ramatically expanded in the past decade, the subcellular location of small RNA-mediated RNA silencing

217 ols for mapping the spatial distribution and subcellular location of target analytes.

218 proteolytic activity, without affecting the subcellular location of the enzyme.

219 t-inducible nuclear exporter, to control the subcellular location of the H2Bub1 E3 ligase, Bre1.

220 This dichotomy is partially explained by the subcellular location of the receptor.

221 ortant activity of plant miRNAs, reveals the subcellular location of this activity, and uncovers a pr

222 together with substantial differences in the subcellular location of this protein between the frog an

223 Here, we determine the steady-state subcellular location of thousands of proteins simultaneo

224 of these three sites dramatically alters the subcellular location of Tmod-1 when introduced into mamm

225 d transporters was quantified by rt-PCR, and subcellular location of transporters was determined by i

226 rgets, we show here their involvement in the subcellular location of two plant proteins.

227 We simultaneously examined the timing and subcellular location of two signaling molecules, MAPK (E

228 itoylation using resin-assisted capture, the subcellular location of yellow fluorescent protein-NCX1

229 P bodies in BMV replication, we examined the subcellular locations of BMV RNAs in yeast cells.

230 ort the protein interactions of Gis2 and the subcellular locations of both Gis2 and CNBP.

231 Furthermore, the activities and subcellular locations of both TcPOT1.1 and TcPOT1.2 in i

232 ned on normal tissue proteins to predict the subcellular locations of cancerous ones is arbitrary bec

233 In addition to documenting the subcellular locations of coding and noncoding transcript

234 Thus, the subcellular locations of D2 and CB1 receptors with respe

235 IEDDA reaction, we precisely pinpointed the subcellular locations of endogenous PLD activity as elic

236 t study sought to determine the cellular and subcellular locations of ERbeta-ir.

237 hat provides a comprehensive analysis of the subcellular locations of Escherichia coli K-12 proteins.

238 port as well as the identity, functions, and subcellular locations of key exported proteins.

239 Despite their important roles, the subcellular locations of many novel thioredoxins has rem

240 staining pattern, which colocalizes with the subcellular locations of mitochondria and the Golgi appa

241 plasm and the nucleus, consistent with known subcellular locations of PIKKs.

242 (BiFC) analysis enables visualization of the subcellular locations of protein interactions in living

243 automatic recognition and comparison of the subcellular locations of proteins in microscope images.

244 Examining the subcellular locations of sequestered compounds in neuron

245 s poorly understood, as are the dynamics and subcellular locations of specific polyubiquitin signals.

246 Electron microscopy was used to assess the subcellular locations of TDP-O-decorated structures.

247 Although both the tissue-specific and subcellular locations of the encoded proteins require fu

248 The nonoverlapping subcellular locations of the three proteins and flavonoi

249 verexpressed in vegetative bacteria, and the subcellular locations of these GFP fusion sites were ana

250 immunogold labeling to determine whether the subcellular locations of these subunits were also altere

251 sites of viral proteolysis, thereby defining subcellular locations of virus priming with greater prec

252 ed after mitotic arrest, we investigated the subcellular location, oligomeric structure, and protein

253 rties on whole cells, ideally indicating the subcellular locations or cytoskeletal associations that

254 acteristic of particular cellular processes, subcellular locations or organs.

255 on was not due to differential phagocytosis, subcellular location, or changes in endosomal acidificat

256 es in the myriad diseases linked to specific subcellular locations, particularly the lysosome.

257 s to intelligently acquire movies of protein subcellular location patterns by learning their models a

258 ss at building automated systems to classify subcellular location patterns in mammalian cells, we sou

259 yn and unveil an intricate interplay between subcellular location, phosphorylation and toxicity, open

260 In this subcellular location, PI3K-C2alpha controlled the activa

261 The nine subcellular locations predicted by pTARGET include cytop

262 Hh:GFP moved to basal subcellular locations prior to release from posterior co

263 unction and role are strongly related to its subcellular location, protein location prediction is an

264 n synaptic transmission is dictated by their subcellular location rather than their subunit compositi

265 obe x-ray absorption measurements at various subcellular locations showed a near-edge feature that is

266 he benchmark data sets that covered up to 22 subcellular location sites and in which none of the prot

267 t at, or move between, two or more different subcellular location sites.

268 ce identity to any other protein in the same subcellular-location subset.

269 on, thermotolerance, senescence, or enriched subcellular locations such as the thylakoid lumen or chl

270 ate with cell adhesion molecules at discrete subcellular locations, such as the nodes of Ranvier.

271 biomarkers, proteins that undergo changes in subcellular location that are indicative of disease.

272 rm an active complex at the correct time and subcellular location through a series of incompletely un

273 We show that Inp1 is present in the correct subcellular location to interact with both the plasma me

274 into the nucleus or localize to a particular subcellular location to regulate Wnt signaling.

275 ization of eNOS is required to deliver NO to subcellular locations to increase endothelial monolayer

276 ust be processed stepwise and at the correct subcellular locations to produce the mature rRNAs.

277 a protein that has been observed at multiple subcellular locations, users may prioritize the visual d

278 Here, we report a study of their subcellular location using the cDNA clone resources of T

279 e labeled particles are retained at specific subcellular locations via DNA hybridization to intracell

280 tremely skewed dataset in which some subset (subcellular location) was about 128 times the size of th

281 In order to observe the impact of number of subcellular locations we constructed two more datasets o

282 facilitate systematic elucidation of protein subcellular location, we analyzed experimentally verifie

283 h tissue type, age, stage of cell cycle, and subcellular location, we determined the reduction potent

284 FRET)-based biosensors localized to discrete subcellular locations, we showed that both NGF and EGF p

285 ascorbate and oxalate/L-threonate, and their subcellular location, were unknown.

286 fractions of protein fluorescence in various subcellular locations when the basic locations in which

287 c accumulation of signaling endosomes at the subcellular location where BDNF concentration is maximal

288 However, the subcellular location where CRY2 exerts its function or u

289 -secretase-mediated processing, although the subcellular location where gamma-secretase cleaves Notch

290 However, the subcellular location where Gbetagamma acts to provoke Go

291 Moreover, the subcellular location where PI(3,5)P(2) regulates TORC1 w

292 Although the SEN complex is conserved, the subcellular location where pre-tRNA splicing occurs is n

293 ich these proteins prevent secretion and the subcellular location where the block in secretion occurs

294 In particular, the subcellular location where this process takes place is u

295 alysis and do not provide information on the subcellular locations where this lipid is synthesized.

296 1 and PDE4 isoforms are targeted to specific subcellular locations which may contribute to the compar

297 goals in cell biology is to determine their subcellular locations, which can provide useful clues ab

298 ns to probe biochemical pathways at specific subcellular locations with exquisite temporal control.

299 rabidopsis proteins have a manually assigned subcellular location, with a strong emphasis on plastid

300 data suggest that Nkd acts at more than one subcellular location within signal-receiving cells to at