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1 he OHIP-G49 was limited to the physical pain subdomain.
2 helicase is regulated specifically by its 2B subdomain.
3 he rotational conformational state of its 2B subdomain.
4 nd the integrin-binding properties of its F3 subdomain.
5 a summary narrative synthesis by domain and subdomain.
6 ses indicated that it can insert into the F2 subdomain.
7 structural parts, called the alpha- and beta-subdomain.
8 IDOL and multiple conformations of its F3ab subdomain.
9 the interaction network at the 3D(pol) palm subdomain.
10 serotonergic group distributed throughout DR subdomains.
11 a QDE2 revealed that the PIWI domain has two subdomains.
12 s in the context of known structural domains/subdomains.
13 accessible to regulation and organized into subdomains.
14 mbrella term, encompassing several disparate subdomains.
15 short segment around V2547 connecting the 2 subdomains.
16 etermined the main input structures to these subdomains.
17 guing that they bud continuously from stable subdomains.
18 nd gamma-catenin reside within its F1 and F3 subdomains.
19 sphatidylinositol synthase (PIS)-enriched ER subdomains.
20 annels cluster together in specific cellular subdomains.
21 omization of Re-chains and formation of ReS2 subdomains.
22 iation with different cellular membranes and subdomains.
23 wo unc-13 (Unc13) isoforms to presynaptic AZ subdomains.
24 provokes a reorganisation of plasma membrane subdomains.
25 score improved significantly, as did 3 of 4 subdomains.
26 omain align more linearly with its F2 and F3 subdomains.
27 tion of IEGs in SPN subtypes within striatal subdomains.
28 e energy profiles for unfolding of talin rod subdomains.
29 sensitive to a specific interaction between subdomains.
30 omatin droplets, mimicking nuclear chromatin subdomains.
31 inct circuit and behavioral functions of its subdomains.
32 ich is involved in physical interaction with subdomain 1 of actin and in stimulating the ATPase activ
37 In particular, conformational changes in subdomain 3 open up multiple favorable interactions with
38 We have identified an interface on IFNAR1-subdomain-3 that is differentially utilized by IFN-beta
39 ture revealed that the CCSSD consists of two subdomains: a juxta-membrane subdomain, which has a nove
40 istinct vertical segments, each with 3 major subdomains: A membrane-connected basal lobe and an apica
42 r to those of other beta-CoVs, the insertion subdomain adopts a novel fold, which is largely invisibl
43 he structures also reveal refolding of an S1 subdomain after ACE2 binding that disrupts interactions
44 hat PINK1 recruits Parkin onto mitochondrial subdomains after actinonin-induced mitochondrial proteot
45 n talin1, its F1 subdomain and additional F0 subdomain align more linearly with its F2 and F3 subdoma
46 ic structural information about the globular subdomains, along with coevolutionary information and an
47 yIIC reveals a novel fold, consisting of two subdomains alphaA-beta1-beta2 and beta3-beta4-alphaB-bet
48 gase domain of SspH1 can be divided into two subdomains: an N-terminal subdomain that harbors the act
50 binding site in the vestigial 3' exonuclease subdomain and a non-catalytic water-bridged magnesium co
51 the PROMIS Global Satisfaction With Sex Life subdomain and a single item from the PROMIS Interest in
52 resemble a cloverleaf, but in talin1, its F1 subdomain and additional F0 subdomain align more linearl
53 firm the mechanosensory role of the talin R3 subdomain and exclude the possibility that the observed
54 acting with a glutamate residue in the 'lid' subdomain and the catalytic glutamate upon ATP binding;
55 of the membrane-binding functions of the F2 subdomain and the integrin-binding properties of its F3
57 equired for proper designation of chromosome subdomains and normal chromosome remodeling in late meio
59 ive impairment at 3 years affected all ACE-R subdomains and was associated with ACE-R 1 year (beta=1.
60 ingernail, attached to the conserved fingers subdomain, and a bundle of 3 helices: 1 from the palm su
61 hagy-initiation complex, the PIS-enriched ER subdomain, and ATG9A vesicles together initiate autophag
63 he rotational conformational state of its 2B subdomain, and its helicase activity has been correlated
65 located in the interface between 2 distinct subdomains, and structural modeling revealed conservatio
66 ains of integrin alphaIIbbeta3, talin1 F2/F3 subdomains, and the kindlin2 FERM domain in an explicit
69 d that topologically associating domains and subdomains are fundamental building blocks of the three-
70 mapping, we demonstrate that the F2PH and F3 subdomains are important for kindlin self-association.
71 aturation CD spectroscopy, we show that both subdomains are required for binding the NTSD with microm
72 st that the intermediate states in talin rod subdomains are stabilized by force during unfolding, and
74 e identified a histone deacetylase 4 (HDAC4) subdomain as a molecular checkpoint of adaptive and mala
77 ollowed by a secretin/TonB, short N-terminal subdomain at the C terminus of the CCSSD, a previously u
78 the position of the AdnA iron-sulfur cluster subdomain at the Y junction and its likely role in maint
79 esults in repositioning of the tetrathiolate subdomain away from the rest of the catalytic domain, th
82 ed that the linker in H. pylori MotB forms a subdomain between the plug and the C-terminal domain, th
84 CUP expression becomes cleared from boundary subdomains between petal primordia, most likely contribu
85 GerK(3) GR, revealing two distinct globular subdomains bisected by a cleft, a fold with strong homol
86 cer cells reveals several unique features of subdomain boundary as compared to domain boundary, inclu
91 a membrane (PM) is composed of heterogeneous subdomains, characterized by differences in protein and
92 ic interactions between two semi-independent subdomains connected by an allosteric switch at Asp52(2.
93 architecture formed by an N- and C-terminal subdomain consisting of eight beta-strands and an alpha-
96 suppresses the segregation of mitochondrial subdomains containing DeltaOTC, it does not decrease the
100 so contains an essential GNRA tetraloop in a subdomain (d10c) that is homologous to poliovirus dIVc.
101 ins, D00-D2, extending into the fifth lectin subdomain (D3) that binds to the Tir-receptor on the hos
102 stepwise destabilization of the talin rod R3 subdomain decreases cellular traction force generation,
103 ases Lro1 and Dga1 are formed at discrete ER subdomains defined by seipin (Fld1), and a regulator of
104 ystal structure, revealing that its F0-F1 di-subdomain displays another unprecedented constellation,
105 Moreover, discriminant analysis using ASD subdomains distinguished between CNV cases with 76% accu
106 he structure, we observed 5 intra- and inter-subdomain disulfide bridges, of which 1 is unique in the
108 oordinated by an independent movement of two subdomains, dsRBD1 and dsRBD2, in which the diffusion di
111 elucidate a mechanism by which a peripheral subdomain enforces stable gene repression and maintains
112 prime CDTa for translocation as the adaptor subdomain enters the lumen of the preinsertion state cha
113 modules and an inward motion of the fingers subdomain-especially the O helix-to engage the primer-te
115 loped for monitoring the rates of individual subdomain folding transitions in situ, in the context of
116 nearly scan upstream chromatin in the 3' Igh subdomain for convergently oriented D-12RSSs and, thereb
121 an unusual sequence and structure containing subdomain homology to thrombospondin type 1 and interleu
122 (TGN) is a central hub divided into multiple subdomains hosting distinct trafficking pathways, includ
123 the SAP domain engages the cleft between NBD subdomains Ia and IIa, stabilizing the ADP-bound conform
126 ne substitutions for the invariant lysine in subdomain II or the aspartate in the DYG-loop of GC-A an
127 ing results revealed beta-C was bound to the subdomain IIA of BSA, the residues of aromatic cluster I
129 its pairwise arrangement with the companion subdomain in each brace of protomers of the DnaB hexamer
131 e synthesized, to which pre- or postsynaptic subdomains in a given neuron type they localize, and whe
134 sed model that the interface between the two subdomains in the NTD of GR A subunits serves as the ger
139 how genomics fits as a specific application subdomain, in terms of well-known 3 V data and 4 M proce
140 tream constant region exon-containing 3' Igh subdomain, in which scanning can be impeded by targeted
141 We find that Fld1 and Nem1 localize to ER subdomains independently of each other and of LDs, but b
142 cial impairment, as well as higher scores on subdomains, indicating deficits in social cognition, soc
148 Compartmentalized signaling in dendritic subdomains is critical for the function of many central
149 containing a Zn(2+)-binding G5 and a spacer subdomain, is responsible for Zn(2+)-dependent assembly
150 to show that nanocompartmentalization of IDR subdomains leads to a remarkably elaborate gating struct
152 ognition is mediated via a four-helix bundle subdomain located in the cytoplasm, which functions as t
155 minus of the beta2AR with the GRK5 RH bundle subdomain, membrane-binding surface, and kinase catalyti
156 al score 3.6% versus 3.7% (p = 0.62) and for subdomains (memory, 5.8% vs. 6.0%; total executive, 3.6%
158 rthermore, MD simulations support rigid body subdomain motions within the FabD structure that may pla
160 -terminal domain bears closest homology to a subdomain of 6-phosphofructokinase, an important enzyme
161 olecule FRET approaches, we show that the 2B subdomain of a UvrD monomer bound to DNA exists in equil
163 mmetry and spindle pole movement towards the subdomain of cortical ER, whereas locally increasing mic
167 ly ascidian embryos possess a large cortical subdomain of endoplasmic reticulum (ER) that causes asym
168 ision.Early ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls as
169 depolymerase Kif2 is localized to a cortical subdomain of endoplasmic reticulum that is involved in a
170 e rotational conformational states of the 2B subdomain of fluorescently labeled UvrD and their rates
179 are associated with functions localized to a subdomain of the endoplasmic reticulum (ER), known as mi
181 depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spind
182 o-TEM revealed IRX9 is present in a specific subdomain of the Golgi stack and was most abundant in th
187 ctivity of a chimeric UvrD containing the 2B subdomain of the structurally similar Rep helicase.
191 localized in the sarcoplasmic reticulum (SR) subdomain of triads where it forms large multimers.
192 NSs bound to the carboxyl-terminal SPRY subdomain of TRIM21, enhancing p62 stability and oligome
193 recovering the conformational ensemble of a subdomain of TrpS affecting the relative stabilities of
196 ound at the meeting point of three different subdomains of desmoplakin: two spectrin repeats and a Sr
199 While the structure of the core and SD-1 subdomains of HKU1 are highly similar to those of other
201 sis on the sequence conservation patterns of subdomains of KCNQ1 and the distribution of pathogenic v
202 in binding site resides within the F1 and F3 subdomains of Kindlin-2 but not the integrin binding sit
205 classes on the basis of their reactivity to subdomains of S protein as well as their cross-reactivit
206 xposed regions and the interface between the subdomains of SERINC5 as critical for HIV-1-restriction
207 e propose that structural differences in the subdomains of the Ag43 classes account for different aut
208 of glutelin and prolamine mRNAs to distinct subdomains of the cortical endoplasmic reticulum is a mo
209 etory protein trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two laye
213 synthetase and the leader- and core-peptide subdomains of the modular HalA2 precursor peptide substr
214 ularly, functionally, and spatially distinct subdomains of the plant TGN and suggest that functional
217 rbon atoms are enriched in secretory vesicle subdomains of the TGN and are critical for de novo polar
218 dCACHE family, a structure with two PAS-like subdomains, one membrane-proximal and the other membrane
219 tion, but the specific roles of different ZI subdomains or cell types have not been well examined.
220 FERM domain structure but show that the F3c subdomain orientation obscures the target-binding site.
222 ral features: an additional novel alpha+beta subdomain placed close to the putative transmembrane alp
223 ease-causing mutations indicate that the two subdomains play pivotal but distinct roles and that the
224 spots are significantly smaller than a Golgi subdomain positive for scaffolding protein AKAP450, whic
225 136 (I136N) and Thr for Ile-142 (I142T) in a subdomain previously named the helical hairpin in the NT
226 HTLV-1 CA CTD, indicating that the HTLV-1 CA subdomains provide distinct contributions to Gag-Gag oli
228 cting WGR domain (W) and the catalytic (Cat) subdomain responsible for the poly(ADP ribosyl)ating rea
229 1 with a mutation in the ligand-binding CRD2 subdomain retained the monomer-to-dimer ratio of the unl
230 S-CoV Sia-binding activity was assigned to S subdomain S1(A) When multivalently displayed on nanopart
233 s disorder (PTSD), all SF-12 physical health subdomain scores were significantly below US norms, and
235 Notably, introducing disulfide bonds between subdomains SD2 and SD3 modulated IFN binding and activit
236 plays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker.
237 ther demonstrate in vivo that the N-terminal subdomain serves as a pedestal for the C-terminal subdom
238 and of MutL-dependent changes in the UvrD 2B subdomain show that the transition from an open to an in
241 ransition from an open to an intermediate 2B subdomain state is on the pathway to helicase activation
242 rates of folding of two or more neighboring subdomain structures using a single mutant to facilitate
243 ither enrichment in or specificity to apical subdomains such as emerging flower primordia, and a larg
244 flexibility is evident throughout the first subdomain, suggesting that the HlyIIC structure may have
246 ia a series of constant region shuffling and subdomain swapping approaches to create improved ("i") c
248 We identify five residues in the insertion subdomain that are critical for binding of neutralizing
249 ra, Chm7, is recruited to a nuclear envelope subdomain that expands upon inhibition of NPC assembly a
250 fied a flexible region within the rigid beta-subdomain that gives way under load, thus opening up the
251 e divided into two subdomains: an N-terminal subdomain that harbors the active-site cysteine and a C-
253 CR extracellular domains contain a conserved subdomain that mediates self-cleavage proximal to the st
254 2) at the 3' end of Igh contains an internal subdomain that spans the 5' CBE anchor (IGCR1)(3), the D
255 teins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perfor
256 partition into the proximo-distally oriented subdomains that convey positional information to these d
257 in loading, leading to generation of dynamic subdomains that directionally align a downstream S regio
258 ochromatin domain, most localize to discrete subdomains that display dynamic localization patterns du
261 zed intramolecular interactions between ZAR1 subdomains that participate in keeping ZAR1 immune compl
262 that it can be divided into three functional subdomains that roughly correspond to the three conserve
263 ising basic residues from both the N1 and N2 subdomains, that directly contributes to 30S-binding aff
264 Moreover, apPOL has an additional N-terminal subdomain, the absence of which severely diminishes its
265 at least partially mapped onto different SC subdomains, the lateral (SCl) and medial (SCm), respecti
266 ure of a cilium can be classified into three subdomains: the intracellular basal body (BB) that templ
268 directly convert into neuroblasts, in an IPC subdomain they generate migratory progenitors by epithel
269 ertoire by establishing protective motifs in subdomain three outside the receptor-binding and dimeriz
270 er and of LDs, but both are required for the subdomains to recruit the TAG-synthases and additional L
271 f the motions of the converter and lever arm subdomains to the rest of the protein and b) a rewiring
275 able region between protein kinase catalytic subdomains VII and VIII, is a common mechanism for stimu
278 The beta1-alpha1-beta2 and alpha2-alpha3 subdomains were separated, and the helix alpha1 was unfo
281 a rigid and closed arrangement of the Galpha subdomain, whereas the apo and GDP-bound forms are consi
282 n, ELC1 appears to engage the MyoA converter subdomain, which couples the motor domain to the neck.
283 main serves as a pedestal for the C-terminal subdomain, which determines the ability of MapZ to mark
284 consists of two subdomains: a juxta-membrane subdomain, which has a novel all-beta-fold, followed by
285 sites of HA are located in the globular head subdomain, which is highly tolerant of amino acid substi
286 ch GRAS domain comprises one alpha/beta core subdomain with an alpha-helical cap that mediates hetero
287 , we provide evidence of a COL4A1 functional subdomain with disproportionate significance for tissue-
288 "mitochondrial RNA granules," mitochondrial subdomains with an emerging role in the regulation of ge
289 -chain length links lipid composition of TGN subdomains with polar secretory trafficking of PIN2 to a
290 to alter the surfaces and the orientation of subdomains with respect to each other, likely resulting
292 nique fold composed of three pseudosymmetric subdomains with shared sequence similarity, a feature no
294 ngle-cell analysis, we identified a cellular subdomain within the midhypocotyl, whose expansion drive
295 ting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (
297 d that exhibits a major rearrangement of the subdomains within the C-terminal two-thirds of PB2 (PB2-
298 e insights into the structural properties of subdomains within the full-length vimentin, in particula
299 reconstruction microscopy (STORM) to define subdomains within the light-sensing rod sensory cilium o
300 ructure and a ZP domain that consists of two subdomains, ZP-N and ZP-C, with ZP-N of ZP2 and ZP3 requ