ライフサイエンスコーパス: submandibular gland

1 anted, but none developed tumors in the left submandibular gland.

2 ression for all 10 known active genes is the submandibular gland.

3 rotid gland, paralleling our findings in the submandibular gland.

4 CB1 receptors on neurons that innervate the submandibular gland.

5 ceptors on cholinergic axons innervating the submandibular gland.

6 axons of cholinergic neurons innervating the submandibular gland.

7 at is essential for saliva production by the submandibular gland.

8 eptor regulates fluid secretion in the mouse submandibular gland.

9 nd correlated with acute inflammation in the submandibular gland.

10 ndrogens have profound effects on the murine submandibular gland.

11 tubule) cells of the neonatal rat and mouse submandibular gland.

12 AdCCs of parotid gland compared to minor and submandibular glands.

13 crease in NOS and BH4 biosynthetic enzyme in submandibular glands.

14 zed a stem cell population from adult murine submandibular glands.

15 on of the cannulated main excretory ducts of submandibular glands.

16 roxylase (TH) in developing murine and human submandibular glands.

17 OC, of acinar and ductal cells in intact rat submandibular glands.

18 mSv/MBq), the kidneys (0.1722 mSv/MBq), the submandibular glands (0.1479 mSv), and the parotid gland

19 e parotid gland, 0.14 to 0.28 Gy/GBq for the submandibular gland, 0.03 to 0.11 Gy/GBq per kidney, and

20 on in the parotids (24% +/- 14%, P = 0.001), submandibular glands (35% +/- 11%, P < 0.001), and kidne

21 ration in the parotids (24% 14%, P = 0.001), submandibular glands (35% 11%, P < 0.001), and kidneys (

22 : the parotid gland (a serous gland) and the submandibular gland (a predominantly mucous gland).

23 diffuse lymphocytic infiltration was seen in submandibular glands, a major target of pSS, by age 6 wk

24 nd the Cl- current were measured in isolated submandibular gland acinar and duct cells to characteriz

25 int of the Ca(2+)-activated Cl(-) current in submandibular gland acinar cells from Best2-deficient mi

26 In contrast, submandibular gland acinar cells from Tmem16A(-/-) mice

27 ected HEK293 cells and from the pancreas and submandibular gland also coimmunoprecipitated EBP50.

28 tive, non-vasomotor sympathetic axons in the submandibular gland and at the base of piloerector hairs

29 1 IFNR (IL14alphaTG.IFNR(-/-)) had the same submandibular gland and lacrimal gland injury as did the

30 lized in the plasma membrane region of human submandibular gland and Madin-Darby canine kidney cells.

31 sly and exogenously expressed TRPC1 in human submandibular gland and Madin-Darby canine kidney cells.

32 glands, specifically in acinar cells of the submandibular gland and palatine minor glands, as well a

33 morphometry and ramification patterns in the submandibular gland and pancreas in order to validate th

34 barium sulphate in the ducts of post-mortem submandibular gland and pancreas specimens harvested fro

35 termined by recording salivary flow from the submandibular gland and temperature changes on the tongu

36 e acinar cells in developing rat parotid and submandibular glands and are also products of the sublin

37 s re-addressed, using isolated, perfused rat submandibular glands and dispersed-cell aggregates from

38 ved in cells isolated from mouse and opossum submandibular glands and rat sublingual and parotid glan

39 ein occurred in the nasal lamina propria and submandibular glands and the frequencies of CD11c+CD8+ d

40 transcripts also are found in the pancreas, submandibular gland, and adult spleen.

41 Results: Tracer uptake by the parotid gland, submandibular gland, and spleen was moderately but signi

42 ively influences gene expression in the male submandibular gland, and that many of the sex difference

43 f androgen control of gene expression in the submandibular gland, and to explore the degree to which

44 of primary salivary tissue, both parotid and submandibular glands, and differentiating hS/PCs, we con

45 ences in ABPs secreted by mouse lacrimal and submandibular glands, and in ABPs secreted by male and f

46 ed phosphorylation of SMAD1/5/8 in the mouse submandibular glands, and led to a recovery of SG functi

47 ed ipsilateral/contralateral parotid glands, submandibular glands, and oral cavity surrogates for eac

48 SMGC is expressed in the submandibular gland at high levels through postnatal day

49 for each organ at risk (kidney, parotid and submandibular glands, bone marrow, liver, and lacrimal g

50 cover that decreasing MT-MMP activity during submandibular gland branching morphogenesis decreases pr

51 required for branching morphogenesis of the submandibular gland but not the lung.

52 This activity appeared in the submandibular glands, but not in the parotid glands.

53 g ClC-3, and ClC-3 protein, was found in rat submandibular gland by RT-PCR and Western analysis.

54 When AdhAQP1 was administered to rat submandibular glands by retrograde ductal instillation,

55 (93%) had parotid carcinoma and 64 (7%) had submandibular gland carcinoma, and 748 (86%) had low-gra

56 , htrp3, and Trp1 were detected in the human submandibular gland cell line (HSG).

57 ty fractions of Triton X-100-extracted human submandibular gland cell membranes.

58 or full-length hTrp1alpha in the HSG (human submandibular gland) cell line.

59 tro stimulation with a muscarinic agonist of submandibular gland cells isolated from mice treated wit

60 Stimulation of human submandibular gland cells with carbachol, inositol trisp

61 In human submandibular gland cells, carbachol (CCh) induced flick

62 th or adhesion of B16-F10 melanoma and human submandibular gland cells.

63 regulating Ca2+ signaling in pancreatic and submandibular gland cells.

64 ivary gland cells as well as dispersed mouse submandibular gland cells.

65 s while plasma cells were enriched in normal submandibular glands compared to other normal gland cont

66 s observed in cultured cells in vitro and in submandibular gland, cortex, and caudate nucleus for as

67 , we report that ex vivo branching of intact submandibular glands decreases when either FGFR2 express

68 Six patients had submandibular gland disease: three with primary neoplasm

69 renergic receptors) in pancreatic acinar and submandibular gland duct cells, respectively, evoke a Ca

70 and membrane current were measured in human submandibular gland ductal (HSG) cells to determine the

71 PC3 was detected in the apical region of rat submandibular gland ducts, whereas TRPC6 was present in

72 The most common manifestations were submandibular gland enlargement, macroglossia, and carpa

73 No staining is seen in submandibular gland epithelial cells (acinar and ductal)

74 AdCCs of the submandibular gland exhibit unique differences in progno

75 deficient adenoviruses, lymphocytes from the submandibular gland express T-bet, GATA3, and RAR-relate

76 embryonic parotid gland as compared with the submandibular gland, focusing on the mesenchymal cell po

77 Immunohistochemical stainings of submandibular glands from C57BL/6.NOD-Aec1Aec2 mice and

78 Submandibular glands from NOD-scid mice exhibited the gr

79 alivation was suppressed by more than 70% in submandibular glands from P2X(7)-null mice.

80 cells as well as lymphocytic infiltrates in submandibular glands from patients with pSS demonstrated

81 show that calcineurin is required for normal submandibular gland function and secretion of digestive

82 the question of a role for 5-HT in mammalian submandibular gland function was re-addressed, using iso

83 The mouse submandibular gland has been used as a model for major s

84 Silencing Cav1 in human submandibular gland (HSG) cells decreased plasma membran

85 The culture of human submandibular gland (HSG) cells on laminin-1 induces aci

86 contribute to [Ca(2+)](i) increases in human submandibular gland (HSG) cells.

87 F, and administration of beta-NGF from mouse submandibular glands induced ovulation in llamas.

88 ion of adenylyl cyclase and, at least in rat submandibular gland, involved in modifying the volume an

89 t adenoviral-mediated gene transfer to mouse submandibular glands is possible by intraductal cannulat

90 Branching morphogenesis of mouse submandibular glands is regulated by multiple growth fac

91 respectively), AdhAQP1 administration to rat submandibular glands led to a two- to threefold increase

92 egions of interest on lacrimal, parotid, and submandibular glands; left ventricle; liver; spleen; kid

93 Submandibular gland lysates were examined by Western blo

94 15 and 5-lipoxygenase) is expressed in mouse submandibular glands (mSMG), using qPCR and Western blot

95 generation in a wound-healing model of mouse submandibular glands (mSMGs).

96 ations of this stem cell population into the submandibular gland of irradiated mice successfully rest

97 tic ductal cells were injected into the left submandibular gland of the same hamsters.

98 Expression of TAg in the submandibular gland of transgenic mice from the time of

99 an hamsters were transplanted into the right submandibular glands of 50 female hamsters that were or

100 of immunoglobulin A (IgA) was studied in the submandibular glands of anaesthetized rats by stimulatin

101 on was upregulated upon radiation therapy in submandibular glands of both mice and humans.

102 y of a replication-deficient adenovirus-5 in submandibular glands of C57BL/6 mice through retrograde

103 Temporal expression of IL-17 and IL-23 in submandibular glands of C57BL/6.NOD-Aec1Aec2 mice correl

104 d enriched the number of functional acini in submandibular glands of irradiated animals and enhanced

105 The exocrine pancreas, liver, and submandibular glands of the rat were used to express and

106 ional significance of FGFR1 was confirmed by submandibular gland organ culture.

107 measurements from time-lapse images of mouse submandibular gland organ explants to construct a tempor

108 chain reaction studies in cells of mammalian submandibular gland origin using consensus sequence prim

109 d 4.35 Gy/GBq (1 study, 18 patients) for the submandibular glands (P = 0.56), 11.03 Gy/GBq (6 studies

110 noculation with tcMCMV, lymphocytes from the submandibular gland preferentially express the transcrip

111 or agonists induced salivation in an ex vivo submandibular gland preparation.

112 93), spinal cord (PRP, 64%; mean SUV, 2.12), submandibular glands (PRP, 53%; mean SUV, 2.11), parotid

113 caspase-3, lack of leukocyte infiltration of submandibular glands, reduced synthesis of disease-assoc

114 ped large ductal-type adenocarcinomas in the submandibular gland region, where islets were transplant

115 ain/neck muscles, and sialorrhea/parotid and submandibular glands (reporting odds ratios 0.79-0.27).

116 tion of Hedgehog signaling within the murine submandibular gland rescued radiation-induced salivary g

117 ncreased by LPS-induced periodontitis in the submandibular gland, returned to control values after HU

118 The submandibular glands showed significant ultrasonographic

119 H+ exchanger (NHE) isoforms expressed in the submandibular gland (SMG) acinar and duct cells and thei

120 l-]i and the Cl- current in the rat salivary submandibular gland (SMG) acinar and duct cells was used

121 ned miRNAs expressed in the mouse developing submandibular gland (SMG) and found that miR-200c accumu

122 y studies have been done to understand mouse submandibular gland (SMG) branching morphogenesis, littl

123 a critical role for heparanase during mouse submandibular gland (SMG) branching morphogenesis.

124 Parasympathetic innervation is critical for submandibular gland (SMG) development and regeneration.

125 -inducible Cre recombinase Ela-CreERT in the submandibular gland (SMG) ductal cells, was established

126 Here, our results show that in primary mouse submandibular gland (SMG) epithelial cells, P2X7R activa

127 The mouse submandibular gland (SMG) epithelium undergoes extensive

128 f the vector to the parotid gland (PTG), the submandibular gland (SMG) or to the liver via the tail v

129 However, the lineage of submandibular gland (SMG) progenitor cells remains less

130 epth analysis of male and female adult human submandibular gland (SMG) samples by bulk RNA sequencing

131 y the latter two develop inflammation in the submandibular gland (SMG), a critical target of Sjogren'

132 ery (BA), middle cerebral artery (MCA)], the submandibular gland (SMG), and pineal gland was quantifi

133 king the regenerative response of the murine submandibular gland (SMG), following innate immune-media

134 infiltration and caspase-3 activation in the submandibular gland (SMG), production of antinuclear and

135 nants of duct specification in the embryonic submandibular gland (SMG).

136 being found only in the acinar cells of the submandibular gland (SMG).

137 ctive of this study was to determine whether submandibular glands (SMG) from ALX/FPR2(-/-) mice displ

138 involved in SPM biosynthesis were altered in submandibular glands (SMG) from NOD/ShiLtJ female mice a

139 sequently, this DC subset became resident in submandibular glands (SMGs) and nasal passages (NPs) in

140 Using ex vivo cultured embryonic mouse submandibular glands (SMGs) as models to study branching

141 cumulation of PSMA-targeting radioligands in submandibular glands (SMGs) can be explained with PSMA e

142 gle-cell RNA sequencing, we found that mouse submandibular glands (SMGs) contain 2 distinct self-rene

143 ear antibodies (ANA) and inflammation in the submandibular glands (SMGs) in SjS females and in restor

144 issues such as the nasal passages (NPs), the submandibular glands (SMGs), and nasopharyngeal-associat

145 Salivary glands, such as submandibular glands (SMGs), are composed of branched ep

146 equired for branching morphogenesis of mouse submandibular glands (SMGs).

147 ated the function of laminin alpha5 in mouse submandibular glands (SMGs).

148 ce lacked comparable defects in the lung and submandibular gland, suggesting that MT1-MMP acts via me

149 rt a RCC case with metastasis to parotid and submandibular glands that has the same sonographic and s

150 DNA levels were lower in the spleen than in submandibular glands, the number of individual viral gen

151 Of the different cells isolated from the submandibular gland, this specific population, Lin-CD24+

152 ike the induced pancreatic tumors, all three submandibular gland tumors that were examined had the mu

153 pine-stimulated in vivo fluid secretion from submandibular glands was essentially normal in double-nu

154 odel of severe glandular injury in the mouse submandibular gland, we show that de novo formation of a

155 Sixty lesions, 14 kidneys, and 10 submandibular glands were delineated in the SPECT/CT dat

156 ean dose, 0.26 Gy/GBq, was seen in the right submandibular gland, whereas the lowest mean dose, 0.029

157 bulated solid mass was detected in the right submandibular gland with similar sonographic findings.

158 previously demonstrated, immunization of the submandibular gland with tissue culture-derived murine c

159 rare condition characterized by swelling of submandibular glands with complete restitutio ad integru

160 al saliva obtained from both the parotid and submandibular glands, with highest levels of activity pr