ライフサイエンスコーパス: submaximal

1 ed to 6 Hz or less and pressure amplitude is submaximal.

2 ise (KE), where ventilation is assumed to be submaximal.

3 all tolerant subjects mainly in response to submaximal 0.1 mug/ml allergen concentration.

4 The glucose clamp studies were performed at submaximal (4 mU/kg/min) and maximal (25 mU/kg/min) insu

5 s had worse maximal (peak oxygen uptake) and submaximal (6-min walk distance) exercise capacity (p <

6 cular fibrillation conversion success with a submaximal 65-J shock.

7 decreased the slack sarcomere length (SL) at submaximal activating [Ca(2+)] and increased the steepne

8 We compared contraction kinetics obtained at submaximal activation at steady-state SL with contractio

9 uscle troponin activation increases force at submaximal activation in both wildtype and NEB KO fiber

10 CK-2066260 greatly increased k(tr) at submaximal activation levels in both WT and NEB KO fiber

11 Partial agonists produce submaximal activation of ligand-gated ion channels.

12 Thus, during submaximal activation of muscarinic receptors, V(m) can

13 xcess again, the UPR transitions to chronic, submaximal activation, indicating that the UPR senses ER

14 rs between striated muscle cell types during submaximal activations.

15 e determination of mitochondrial function at submaximal activity rates, which is more physiologically

16 age on the hemodynamic response to prolonged submaximal aerobic exercise in healthy volunteers.

17 red 15 minutes seated at rest, followed by a submaximal aerobic exercise on a treadmill and then rema

18 By stimulating neurons with a submaximal agonist concentration before (R1) and after (

19 Consistent with this result, at submaximal agonist concentrations, the activation kineti

20 sthetics halothane and isoflurane potentiate submaximal agonist responses at wild-type receptors, via

21 calcium, 80 mg/d, or rosuvastatin, 40 mg/d; submaximal: all other dosages).

22 ptosis, however, coexpression of DAP4 with a submaximal amount of MST1 enhances MST1-induced apoptosi

23 ine production by these cells in response to submaximal amounts of anti-CD3 and anti-CD28.

24 licited currents with slow-rising phases and submaximal amplitudes.

25 refractoriness, these performance gains are submaximal and energetically costly.

26 ed arteriovenous shunting in all subjects at submaximal and in 4/7 subjects at maximal exercise inten

27 e recruitment and detachment slowed for both submaximal and maximal Ca(2+)-activated conditions.

28 f the muscle vasodilatation that accompanies submaximal and maximal contractions.

29 Accommodation was centrally stimulated with submaximal and maximal current amplitudes.

30 acity ( VO2max ), cardiovascular function at submaximal and maximal exercise, left ventricular mass a

31 (MCE) and wall motion analysis (WMA) during submaximal and peak dobutamine stress echocardiography (

32 icular-arterial coupling is preserved during submaximal and peak exercise in the healthy heart.

33 During submaximal and peak exercise, there were significant inc

34 in the healthy heart during rest, as well as submaximal and peak exercise.

35 esting pre- and post- training included: (a) submaximal and peak; (b) prolonged (60 min) submaximal e

36 human dosage of LAmB 3 mg/kg/d resulted in a submaximal antifungal effect.

37 APHR compared with those with normal SE with submaximal APHR (p<0.0001; 95% CI: 2.81 to 5.08).

38 78% higher in patients with abnormal SE with submaximal APHR compared with those with normal SE with

39 Patients with submaximal APHR in the setting of normal SE have a highe

40 Thus, the results of submaximal APHR in the setting of normal SE should be ta

41 This effect is submaximal as CD28 costimulation coupled to TCL1 express

42 EPO induction was submaximal, as hypoxia or pharmacologic PHD inhibition f

43 This effect was time dependent, submaximal at 1 nM, and comparable in potency to epiderm

44 At submaximal ATP concentrations, Ap(5)A stimulated current

45 nner under conditions where Anr activity was submaximal because of the presence of oxygen.

46 Contractile reserve during submaximal beta-adrenergic stimulation is attenuated in

47 Under submaximal beta-adrenoceptor stimulation of brown adipoc

48 ropose that the Apc(1322T) mutation produces submaximal beta-catenin levels that promote early tumor

49 rease in ICa,L sensitivity to stimulation by submaximal beta1-AR activation using isoproterenol (Iso)

50 ter (i) overnight rest (nonexercise) or (ii) submaximal bicycle exercise.

51 <140/90 mm Hg [nonhypertensive]) performing submaximal Bruce treadmill tests were followed for 20 ye

52 Further, failing to consider submaximal but reliable population responses can lead to

53 f partial mGlu5 NAMs, characterized by their submaximal but saturable levels of blockade, may represe

54 ng thin filament activation, particularly at submaximal Ca(2)(+) levels, even though XB-RU cooperativ

55 creased linearly with dATP/ATP ratio, but at submaximal Ca(2+) (pCa 5.5) this relationship was nonlin

56 These effects were greater for submaximal Ca(2+) activated contractions.

57 Thus, force only increases at submaximal Ca(2+) activation due to cooperative recruitm

58 M only increases myocardial contractility at submaximal Ca(2+) activation levels and not maximal Ca(2

59 nd 1.0 mumol/L) enhanced force generation at submaximal Ca(2+) activations in a dose-dependent manner

60 and a slowed rate of XB detachment (krel) at submaximal Ca(2+) activations.

61 tile mechanics were monitored at maximum and submaximal Ca(2+) concentrations.

62 ity that persisted in the presence of Tn and submaximal Ca(2+) Furthermore, decreasing the extent of

63 actile activation (kACT) at maximal, but not submaximal Ca(2+), and reduced the Ca(2+) sensitivity of

64 ivate the thin filament regulatory system at submaximal Ca(2+).

65 er the rate of force redevelopment (ktr ) at submaximal [Ca(2+) ].

66 tachment time was significantly prolonged at submaximal [Ca(2+)] (pCa >/=6.5) in HTN patients.

67 ay prolonged cross-bridge attachment time at submaximal [Ca(2+)] without a change in the tension-pCa

68 nd increased cross-bridge cycling (k(tr)) at submaximal [Ca(2+)].

69 lso induced auto-oscillatory contractions at submaximal [Ca(2+)].

70 At submaximal Ca2+ activation, PKD-mediated phosphorylation

71 e rate of isometric force development during submaximal Ca2+ activations and suggest that the rate of

72 etch of skinned myocardium during maximal or submaximal Ca2+ activations resulted in an instantaneous

73 enhanced myofilament tension in response to submaximal Ca2+ under physiological ionic conditions.

74 found to increase from 1.11 +/- 0.21 s-1 at submaximal [Ca2+] (pCa 6.0) to 9.28 +/- 0.41 s-1 during

75 At submaximal [Ca2+], the thin filament regulatory system m

76 rations, velocity was reduced at maximal and submaximal calcium in the presence of Pi.

77 thin filament activation at both maximal and submaximal calcium levels, with the relative contributio

78 n of myosin strong binding being greatest at submaximal calcium.

79 However, submaximal cAMP-dependent protein kinase activation had

80 tentiation of the Ca(2+)-mediated Isc and of submaximal cAMP-mediated responses.

81 r the entire population and was lower in the submaximal capacity subgroup compared with the maximal c

82 olume responses, or enhance those induced by submaximal [CCh], because the magnitude of the changes w

83 We believe that a "Goldilocks Window" of submaximal chemotherapy will yield improved overall outc

84 th l-dopa (7 mg/kg ip) that alone produced a submaximal circling response, ST1535 enhanced the intens

85 d alveolar fluid clearance (< 3%/h), 32% had submaximal clearance (> or = 3%/h, < 14%/h), and 13% had

86 se mortality in patients with normal SE with submaximal compared with maximal APHR (relative risk: 1.

87 ne) was 127% higher in patients who achieved submaximal compared with those with maximal APHR (annual

88 ine) was 70% higher in patients who achieved submaximal compared with those with maximal APHR (annual

89 cAMP synthesis was slightly elevated with a submaximal concentration of 7-deacetyl-7-(O-[N-methylpip

90 could amplify the aggregation response to a submaximal concentration of ADP.

91 receptors from rats show potentiation when a submaximal concentration of ATP is combined with zinc in

92 ed rather than antagonized the response to a submaximal concentration of clobenpropit.

93 nd that inhibition of glutamate release by a submaximal concentration of enkephalin was doubled by ap

94 l act as potentiators of responses evoked by submaximal concentrations of 5-HT.

95 of these gene promoters in cells exposed to submaximal concentrations of Akti-1/2; however, full rep

96 The response of P2X(2) receptors to submaximal concentrations of ATP is potentiated by low l

97 ssium channel (Kir3.X) (GIRK) conductance by submaximal concentrations of Met(5)-enkephalin (ME) and

98 Activation of PKD by submaximal concentrations of phospholipase C-coupled rec

99 rrents increase with repeated application of submaximal concentrations of RTX until a maximal respons

100 Low concentrations of FGF2 combined with submaximal concentrations of T4 produced an additive ang

101 d potentiate receptor activation elicited by submaximal concentrations of the transmitter.

102 Fatigue reduced the complexity of submaximal contractions (ApEn to 0.24 +/- 0.05; SampEn t

103 r power capacity of muscle, which means that submaximal contractions can be sustained after the onset

104 Fresh submaximal contractions were more complex than maximal c

105 Fresh submaximal contractions were more complex than maximal c

106 regulation and neurovascular coupling during submaximal cycling exercise and temperature-matched pass

107 pnia (i.e. end-tidal PCO2 was held constant) Submaximal cycling exercise and temperature-matched pass

108 uring 50% maximal oxygen uptake steady-state submaximal cycling exercise.

109 At room temperature, the SOCE induced by submaximal depletion of the SR Ca(2+) store was signific

110 In HFpEF during submaximal dobutamine stress, there is myocardial mechan

111 Studying adult ICU patients receiving VPI at submaximal dosages, we analyzed characteristics of susta

112 nhanced arthritis when coadministered with a submaximal dose of anti-CII antibodies and bound targets

113 Combination therapy with Ad PDGFRbeta and submaximal doses of Ad Flk1-Fc produced modest additive

114 Cotreatment of muscle cells with submaximal doses of INH and insulin resulted in an addit

115 cells promoted the [Ca(2+)]c rise evoked by submaximal doses of IP3, indicating that O2 directly sen

116 given alone and to potentiate the effects of submaximal doses of l-dopa.

117 0 mm l-phenylalanine and 1 microm NPS R-467, submaximal doses of the two agents, each elicited simila

118 regenerative ability in animals treated with submaximal doses of vincristine.

119 th cisplatin, ABDNAZ was better tolerated at submaximal doses, yielding significant tumor growth inhi

120 CI, 0.87-0.94) compared with those receiving submaximal doses.

121 The prognostic value of a negative-submaximal DSE study before noncardiac surgery is unknow

122 ut not glycine activates NMDA receptors with submaximal efficacy.

123 inematics, kinetics, and metabolic demand of submaximal effort movement.

124 Furthermore, pairing submaximal endogenous activation of metabotropic glutama

125 submaximal and peak; (b) prolonged (60 min) submaximal endurance and (c) high-intensity intervals.

126 t maximal ppERK responses initially occur at submaximal ERK levels and that this non-monotonic relati

127 e text]e/[Formula: see text]co2 ratio during submaximal exercise (r=0.780, P<0.001).

128 The combination of submaximal exercise and hypoxia produces a 'compensatory

129 eathing) were examined at rest, steady-state submaximal exercise and maximal exercise (maximal oxygen

130 counterregulatory failure during subsequent submaximal exercise and may increase the risk of exercis

131 titial space was measured at rest and during submaximal exercise at Pre, 1 week and 8 weeks.

132 nderwent echocardiography at rest and during submaximal exercise before completing a maximal test to

133 and left ventricular mass nor did it improve submaximal exercise capacity or quality of life.

134 e and did not have better quality of life or submaximal exercise capacity than did patients who recei

135 d points included change in quality of life, submaximal exercise capacity, and left ventricular eject

136 .min(-1); P=0.003) and significantly reduced submaximal exercise capacity, as determined by the oxyge

137 , improvement in biventricular function, and submaximal exercise capacity.

138 finity haemoglobin (HAH) affects maximal and submaximal exercise capacity.

139 reduces blood pressure and the O(2) cost of submaximal exercise in humans.

140 ng the onset of moderate and heavy intensity submaximal exercise in humans.

141 AMPK, regulates muscle glucose uptake during submaximal exercise in vivo.

142 An additional increase with submaximal exercise occurred in controls only.

143 ing mechanical ventilatory constraint during submaximal exercise on dyspnoea in older men and women.

144 Submaximal exercise parameters, such as ventilatory effi

145 nction (Short Physical Performance Battery), submaximal exercise performance (6-Minute Walk Test), st

146 le function, pulmonary function, maximal and submaximal exercise performance or quality-of-life quest

147 Maximal and submaximal exercise performance, respiratory and quadric

148 eas supplementation with nitrate can improve submaximal exercise performance.

149 hat patients with HFpEF develop B-lines upon submaximal exercise stress echocardiography; however, wh

150 5, 53% women, mean age 59 years) underwent a submaximal exercise test (first 2 stages of the Bruce pr

151 Therefore, this simple, submaximal exercise test might be useful for assessing p

152 rdiorespiratory fitness was assessed using a submaximal exercise test to estimate maximum oxygen cons

153 rform less well either on a 6-minute walk or submaximal exercise testing despite increased right-to-l

154 e lower LVapical rotation at rest and during submaximal exercise that can occur without changes in gr

155 , maximal aerobic capacity ( V O(2) max) and submaximal exercise tolerance (i.e. speed-duration relat

156 t that vascular K(ATP) channels help sustain submaximal exercise tolerance in healthy rats.

157 e yearlings were randomly assigned to either submaximal exercise training or no forced exercise (untr

158 from wk 0 to 9, and also not in response to submaximal exercise training.

159 During submaximal exercise workloads (20-60% Wmax), despite an

160 se economy (i.e. metabolic cost of sustained submaximal exercise) does not change with age in enduran

161 (exhaled nitric oxide [NO] production during submaximal exercise) were prospectively assessed in 259

162 During submaximal exercise, HFpEF subjects displayed reduced to

163 hial artery and exhaled NO production during submaximal exercise, is associated with an increased mor

164 Neither prolonged submaximal exercise, nor high-intensity intervals, nor s

165 During submaximal exercise, physiological mitochondrial fragmen

166 During submaximal exercise, the transpulmonary gradient and pul

167 diastolic untwisting rate (UTR) at rest and submaximal exercise.

168 roved ventilatory efficiency during peak and submaximal exercise.

169 kle tracking echocardiography at rest and on submaximal exercise.

170 e of T(c) from PCO2 on CBF regulation during submaximal exercise.

171 iting to fat oxidation during high intensity submaximal exercise.

172 al responses were observed during prolonged, submaximal exercise.

173 does not limit PCr kinetics at the onset of submaximal exercise.

174 ) at a given oxygen consumption (VO2) during submaximal exercise.

175 s with PH were unable to increase Ees during submaximal exercise.

176 epletion and lactic acid accumulation during submaximal exercise; this adaptation is mediated by an i

177 During submaximal exertion at comparable heart rates (114+/-6 v

178 l activity while they performed two types of submaximal fatiguing isometric contraction that required

179 c free [Ca(2+) ] required to produce a given submaximal force and hence decreasing the energy require

180 vation and relaxation kinetics nor the final submaximal force development differed significantly betw

181 Significantly, at equivalent levels of submaximal force k(tr) was faster at short SL or increas

182 brillar Ca(2+) sensitivity and amplifies the submaximal force response.

183 Fluctuations in F(z) during the submaximal force-matching tasks were 2.45x greater (p<.0

184 blation of cMyBP-C-accelerated k(tr) at each submaximal force.

185 d ability to accurately and steadily control submaximal force; and impaired eccentric strength.

186 mal voluntary contractions (MVCs) and steady submaximal forces (2.5 and 10% MVC) with the fingertip o

187 t the effects of NEM-S1 to increase k(tr) at submaximal forces and thereby markedly reduce the activa

188 nesin-2 motors were more likely to detach at submaximal forces, and the duration of force maintenance

189 rrents activated more slowly when exposed to submaximal GABA concentrations, had more fast desensitiz

190 iazepam, only potentiate currents induced by submaximal GABA concentrations.

191 esthetics potentiate the currents induced by submaximal GABA concentrations.

192 of propofol or pregnanolone to potentiate a submaximal GABA response, but the Q185A mutant exhibited

193 Agonists at the BDZ binding site potentiate submaximal GABA responses by increasing the apparent aff

194 Potentiation of submaximal GABA(A) receptor currents by the neurosteroid

195 Low concentrations potentiate submaximal GABA-induced currents.

196 secrete adenosine diphosphate in response to submaximal gamma-thrombin concentrations that cause secr

197 lutionarily preserved to achieve optimal-but submaximal-GLS activity.

198 A clear hypersensitivity to submaximal glucose concentrations was evident in INS-1 c

199 S), but only in the presence of intermediate/submaximal glucose concentrations.

200 onal cell death, however, when combined with submaximal glutamate (3.3 mM), TNF alpha significantly i

201 To estimate physical fitness, a submaximal graded exercise test was performed on a bicyc

202 from previously diagnosed CVD who underwent submaximal graded exercise treadmill testing to achieve

203 ency among the negative-maximal and negative-submaximal groups (6 of 335, 1.8% vs. 1 of 62, 1.6%, res

204 Because wild-type mice exhibited submaximal HIF accumulation in response to no-flow ische

205 ditions where thin filament sliding speed is submaximal (i.e. in the presence of troponin and tropomy

206 in METH-pretreated D(2) mutants but remained submaximal in METH-pretreated D(3) mutants.

207 All identified TrbA operators are submaximal; in the case of trbBp, a G to A transition th

208 at prevents a supply-demand imbalance during submaximal increases in cardiac workload when coronary f

209 A biopsy of the vastus lateralis muscle and submaximal incremental exercise was performed before and

210 duction response could be heterogeneous at a submaximal inducer concentration.

211 y cytoprotective at concentrations that gave submaximal inhibition of macroscopic currents in oocytes

212 f InsP(3)R2 was enhanced by ATP, but only at submaximal InsP(3) levels.

213 sP(3)-mediated Ca(2+) release in response to submaximal InsP(3) stimulation in permeabilized wild-typ

214 tal muscle, glucose transport in response to submaximal insulin (450 microU/ml) was measured in isola

215 % increase in glucose disposal (p < 0.05) at submaximal insulin but no increase at maximal insulin co

216 This submaximal insulin concentration promotes an intermediat

217 nhanced insulin-stimulated glucose uptake at submaximal insulin concentrations and reversed the inhib

218 -surface Glut4 in adipocytes stimulated with submaximal insulin concentrations.

219 At submaximal insulin doses, protection was potentiated by

220 Relative to WL5, submaximal insulin-stimulated 2-deoxyglucose uptake into

221 eceptor beta-subunit (IRbeta) protein level, submaximal insulin-stimulated IRbeta tyrosine phosphoryl

222 sine phosphorylation of the IR stimulated by submaximal insulin.

223 , or underwent 30 min of electrically evoked submaximal intensity isometric contraction using a perfu

224 control subjects without PH who performed a submaximal invasive cardiopulmonary exercise test betwee

225 lso facilitated the Ca(2+) release evoked by submaximal IP3 in permeabilized DKO1 and DKO2 but was in

226 motor units) during the plateau phase of the submaximal isometric contractions (P < 0.001).

227 ts with chronic stroke performed a series of submaximal isometric elbow flexion tasks.

228 was decreased from 2.3 microm to 2.0 microm submaximal isometric force decreased approximately 40% i

229 During submaximal LBNP, FVR increased in HT (ANOVA P < 0.05) bu

230 and forearm vascular resistance (FVR) during submaximal LBNP.

231 est, followed by running on a treadmill at a submaximal level and then remained seated for 60 min dur

232 endent translation, which is maintained at a submaximal level during hypertrophic growth and point to

233 eveloped antiphage antibodies that reached a submaximal level within the 10-day protocol window for s

234 Repeated administration of C75 at a submaximal level, however, differentially affected food

235 of Rac1 maintains the number of spines at a submaximal level.

236 ondrial function in human skeletal muscle at submaximal levels and at a predefined membrane potential

237 IRES activity is then maintained at submaximal levels during hypertrophic growth of these ce

238 force was inhibited by Vi k(TR) increased at submaximal levels of Ca(2+)-activated force.

239 Data were obtained at rest, two submaximal levels of exercise below ventilatory threshol

240 Plant populations frequently maintain submaximal levels of resistance to natural enemies, even

241 At similar submaximal levels of steady-state force there was no inc

242 nstrate that both Bmp and Wnt are present at submaximal levels, which allows the pathways to function

243 ontraction and MAS of the knee flexors using submaximal loads relative to the individual's maximum vo

244 synapse and activation of mGlu7 potentiated submaximal LTP.

245 These data suggest that during submaximal metabolic rates, the relationship between (.-

246 rogressively recruited for the full range of submaximal muscle activation in all conditions.

247 controlling human eccentric than concentric submaximal muscle contractions.

248 When cytoplasmic Na is submaximal, Na/K pump currents decay rapidly during extr

249 In cultures treated with submaximal NMO-IgG, the severity of NMO lesions was incr

250 augmentation of response frequencies at all submaximal peptide doses by CD28- and CD49d-mediated cos

251 ealthy subjects, with better preservation of submaximal performance.

252 We hypothesized that in response to submaximal pharmacologic stress (dobutamine), patients w

253 ther the background statin was of maximal or submaximal potency.

254 a suggest that integrase has evolved to have submaximal processing activity so that it can also catal

255 in accurately matching target forces during submaximal quadriceps contractions and in the same tasks

256 sometric and isokinetic force in response to submaximal rates of nerve stimulation in situ producing

257 ndlimb muscle force and power in response to submaximal rates of nerve stimulation in situ.

258 vidence that enhancer specificity depends on submaximal recognition motifs having reduced binding aff

259 on than with enteral nutrition that approach submaximal response levels and direct appearance of admi

260 TDBzl-etomidate (>10 microm) increased the submaximal response to acetylcholine (10 microm) with a

261 ), and higher Zn2+ concentrations inhibiting submaximal responses to glycine.

262 The prognostic value of a normal but submaximal SE (<85% of maximal APHR) is conflicting.

263 quency and duration of channel openings to a submaximal state.

264 Among patients who arrived on submaximal statins, 26% had their statin therapy intensi

265 rt rate measurement following a standardized submaximal step test; muscular fitness was assessed by m

266 nd concentration-dependent force increase at submaximal stimulation frequencies.

267 However, at submaximal stimulation frequency, force was reduced in K

268 enhance activation of neutrophils exposed to submaximal stimulatory doses of LPS.

269 by 45% (p<0.05) the area of the AP evoked at submaximal stimulus intensity.

270 157% (p<0.05) the area of the AP evoked at a submaximal stimulus intensity.

271 d convergence of RUNT domain residues toward submaximal strength.

272 vity than WMA, particularly in patients with submaximal stress and in identifying patients with multi

273 (CFR) by positron emission tomography, where submaximal stress precludes assessing physiological seve

274 phic examination with DTI at rest and during submaximal supine bicycle exercise.

275 ing NW width, and the selectivity to measure submaximal synaptic concentrations of DA in the presence

276 Administration of submaximal tamoxifen allowed genetic labeling of single

277 e or muscarinic acetylcholine receptors with submaximal TBF unmasked associative iLTD.

278 ited immunosuppression, or in the context of submaximal TCR or costimulatory signals, targeting of PD

279 raded, progressive protocol, and a prolonged submaximal test (70% peak intensity for 45 min) were adm

280 maximal voluntary contractions, MVCs), and a submaximal test (contractions at a target of 40% MVC per

281 Perceived dyspnea during the submaximal testing was decreased.

282 atients, intensification in those undergoing submaximal therapy, and discharge on maximal therapy (de

283 e of proteasome inhibitors, in particular at submaximal TRAIL doses.

284 microsphere infusions) were measured during submaximal treadmill running (20 m min(-1), 5% grade).

285 ial effects of ingestion of avocado prior to submaximal treadmill running.

286 Of 4,860 eligible for a submaximal treadmill test, 3,250 completed the test and

287 Subjects also completed a submaximal treadmill test, Timed-Stands Test, and 50-Foo

288 tween the HAP scores and the questionnaires, submaximal treadmill test, Timed-Stands Test, and 50-Foo

289 jects with arthritis completed the HAP and a submaximal treadmill test.

290 VO(2max) was estimated from the submaximal treadmill test.

291 diovascular performance throughout prolonged submaximal upright cycle ergometry in 40 carefully scree

292 c reserve performance occur during prolonged submaximal upright cycle ergometry, analogous to those o

293 Below CS V(O2) stabilized at a submaximal value (58.5 +/- 2.5 ml kg(-1) min(-1)) wherea

294 lex than maximal contractions (mean +/- SEM, submaximal vs. maximal: ApEn 0.65 +/- 0.09 vs. 0.15 +/-

295 plex than maximal contractions (mean +/- SEM submaximal vs. maximal: ApEn 0.65 +/- 0.09 vs. 0.15 +/-

296 iovascular response to prolonged exercise at submaximal work rates typical of daily aerobic activitie

297 At submaximal work rates, there was no significant differen

298 e heart rate response to reference levels of submaximal work.

299 outs (5 min duration; order randomised) at a submaximal workload while breathing 0.1, 0.21 or 1.0 F(I

300 d rate-pressure product (RPP) at maximal and submaximal workloads were assessed.