ライフサイエンスコーパス: substantial difference

1 t 10 percentage points was prespecified as a substantial difference.

2 recent deglacial-interglacial intervals show substantial differences(1-3) despite both periods underg

3 Substantial differences across countries and over time r

4 mes as many as previously estimated and with substantial differences across countries/regions.

5 There are substantial differences across species in the organizati

6 The miRNome and proteome showed substantial differences across the sEV groups and bioinf

7 (FEBS Lett 579[1], 259-64), we did not find substantial difference among the three variants accordin

8 We identified substantial differences among CA, AA, and AS populations

9 High-density mapping shows substantial differences among channels in ventricular sc

10 as stopping CO2 emissions entirely, but with substantial differences among countries, implying differ

11 pic variability are strongest when there are substantial differences among phenotypes and when phenot

12 We detected substantial differences among these factors.

13 vitro and in vivo Genomic comparisons showed substantial differences among three of the isolated clon

14 scripts of multitranscript genes can exhibit substantial differences and demonstrating that the circa

15 ), determined using gel shifts, displayed no substantial differences, and were of the same order as k

16 n the cell-attached configuration, whereas a substantial difference ( approximately 30%) is observed

17 Substantial differences are observed for the extent of o

18 For example, substantial differences are seen when selected cancers i

19 IMP-1 (Protein Data Bank entry 1UEA), we see substantial differences at the binding interface that pr

20 Overall the MAS NMR data indicate a substantial difference between the structure of the fibr

21 roscopic current kinetics also highlighted a substantial difference between the two sets of mutations

22 Our results demonstrate substantial differences between air and surface temperat

23 different F-protein antigenic sites revealed substantial differences between antibodies elicited by A

24 We show that despite substantial differences between axons, the effects of te

25 placements of spoIIQ and spoIVFA, suggesting substantial differences between bacilli and clostridia i

26 d modification studies of the BK S6 point to substantial differences between BK and Kv channels in th

27 ror estimations indicate the possibility for substantial differences between CA- and IA-based assessm

28 cted countries within the study period, with substantial differences between countries, ranging from

29 an represent as much as 35% of fixed N, with substantial differences between cultures using the Mo- a

30 This large study found no substantial differences between dietary methods and obse

31 amino acid sequence, there are in some cases substantial differences between genetic and antigenic di

32 Substantial differences between GLUT1, GLUT4, and GLUT8

33 at were homologous between lineages revealed substantial differences between helices.

34 en irreversible worker and queen castes, but substantial differences between nurses and forager subca

35 The substantial differences between observed and model-based

36 There were substantial differences between officially reported and

37 We also found substantial differences between our identified vertebrat

38 al resistance and an increasing awareness of substantial differences between populations in genetic a

39 es may suffer from publication bias, whereby substantial differences between published and unpublishe

40 alysis of raw sequencing data and we observe substantial differences between recognition by Ago2 of R

41 Theory shows that coexistence requires substantial differences between species, but species-lev

42 Recent studies have demonstrated substantial differences between the brains of breeders a

43 In addition, we detected substantial differences between the cell-type transcript

44 include selective cargo loading resulting in substantial differences between the composition of extra

45 We found substantial differences between the dose estimated by th

46 Although there are substantial differences between the magnetospheres of Ju

47 There were significant, consistent and substantial differences between the mature and immature

48 ginosa gene essentiality datasets, revealing substantial differences between the screens.

49 This suggests that there may be substantial differences between the toxin-binding sites

50 mpus using diffusion imaging showed the most substantial differences between the two groups and was t

51 Because of substantial differences between these 2 groups, propensi

52 A trained panel did not perceive substantial differences between treatments.

53 Furthermore, substantial differences between trypanosomal TyrRS and h

54 teworthy that overall national trends masked substantial differences by place and by educational atta

55 ong conservation of Shaker family in plants, substantial differences can exist between the physiologi

56 gned to T = 3 plant RNA viruses but exhibits substantial differences compared with the insect-infecti

57 Substantial differences exist between county ischemic he

58 Whereas substantial differences exist between familial and spora

59 Substantial differences exist in the clinical characteri

60 Substantial differences exist in the clinical characteri

61 Substantial differences exist in the cognitive styles of

62 In this large observational data set, substantial differences existed according to radiotherap

63 Although substantial differences existed between the two inhibito

64 Our analyses also show substantial difference for DRA genes between young and o

65 IHME GBD estimates for South Africa revealed substantial differences for estimated deaths from all ca

66 h those of unliganded HMGCL and R41M reveals substantial differences for Mg(2+) coordination and posi

67 atively low effective sample sizes indicated substantial differences for patient populations between

68 rs of these three classes of genes displayed substantial differences, highlighting the importance of

69 Substantial differences, however, were found both betwee

70 line in serial repopulating capacity, but no substantial difference in apoptosis or levels of reactiv

71 However, images with a substantial difference in appearance violate this assump

72 There is a substantial difference in cases identified by NLP compar

73 ctural and functional assays demonstrated no substantial difference in functional or structural avidi

74 ng traction force microscopy, we also find a substantial difference in growth cone traction force gen

75 Results No substantial difference in interobserver agreement was ob

76 equency (2850 cm(-1)) SRS imaging revealed a substantial difference in lipogenesis between the flucon

77 base interval in the class I D locus confers substantial difference in MCMV control phenotypes.

78 Irrespective of the length of dormancy a substantial difference in metabolite composition at each

79 No substantial difference in PFS or OS was observed between

80 ntical behaviour in magnitude, but engenders substantial difference in phase between transmitted left

81 and suggested a possible explanation for the substantial difference in reactivity between the t-Bu- a

82 o play an important role, accounting for the substantial difference in reactivity between triaryl and

83 However, there was a substantial difference in the ability of AZD0530 to inhi

84 There was no substantial difference in the accuracy of volume estimat

85 factors in other regions, combined with the substantial difference in the demand pattern for cooling

86 procedures, and second that there would be a substantial difference in the effectiveness of antibioti

87 ed by 6-fold relative to wild type without a substantial difference in the fidelity of 2'-dNMP incorp

88 is the largest reported to date and showed a substantial difference in the genetic causes of RP compa

89 We find no substantial difference in the mass loss of debris-covere

90 Despite a substantial difference in the maximum force generated by

91 ecessarily inhibitory to AAV and highlight a substantial difference in the nature of AAV-binding anti

92 There was also a substantial difference in the signal intensities especia

93 II, has also been completed, demonstrating a substantial difference in the strengths of the Fe-O link

94 As we have shown previously, the substantial difference in time scales is what generates

95 ity and capacity are not associated with any substantial difference in U(VI) coordination.

96 We demonstrate substantial differences in 'adhesive signature' between

97 Substantial differences in acyl-coenzyme A profiles betw

98 No substantial differences in adverse effects were noted be

99 d RH differences that define the UHI lead to substantial differences in aerosol liquid water (ALW) co

100 TSPO ligands showed substantial differences in affinity between subjects cla

101 igher in the influenza-infected lungs due to substantial differences in Ag abundance in the two infec

102 Substantial differences in age at onset were present in

103 Also, turbidity measurements confirm substantial differences in aggregation behavior dependin

104 AIMs exhibit substantial differences in allele frequency between ance

105 region on 8q24 harboring three SNPs showing substantial differences in allelic frequency between cas

106 e for the role of TEs in contributing to the substantial differences in annotated gene content among

107 extent in MSTN(Delta/Delta) muscles, but no substantial differences in atrophy-related genes were ob

108 Substantial differences in average utilities were seen d

109 Both systems detected substantial differences in Bet v 1 content between aller

110 The substantial differences in binding affinity between DAG-

111 Despite these substantial differences in biophysical properties, both

112 pulations that colonize islands often evolve substantial differences in body size from their mainland

113 Substantial differences in bone marrow composition were

114 ta support a growing body of evidence noting substantial differences in cardiovascular risk by ethnic

115 lycan-modifying genes and thus explained the substantial differences in CD16a processing by NK cells

116 ligand independence, ER mutations conferred substantial differences in chromatin accessibility.

117 We use a high-resolution analysis to show substantial differences in chromatin structure of pol II

118 scrimination of risks by the models, despite substantial differences in clinical variables.

119 There were substantial differences in consent rates among racial/et

120 ary and thoracic calcium was robust, despite substantial differences in CT protocol and variations in

121 Substantial differences in diagnostic practices that are

122 tly in vitro and in vivo, but they exhibited substantial differences in disease severity in mammals.

123 There are substantial differences in duration of mechanical ventil

124 pprove drugs for monotherapy) have not shown substantial differences in efficacy between drugs, FDA a

125 lence to established treatments did not find substantial differences in efficacy.

126 n profiles visually exhibited widespread and substantial differences in EGS use and morality.

127 ha1 domains from severe malaria isolates had substantial differences in EPCR binding affinity and blo

128 PE specification can lead to substantial differences in estimated rates of cognitive

129 These studies demonstrate substantial differences in exosomal miRNA profiles betwe

130 Pharmacokinetic alterations resulted in substantial differences in exposure between obese and no

131 These results quantify substantial differences in expression levels of the prot

132 erences in recognition, however, resulted in substantial differences in F105- and b13-bound conformat

133 There were substantial differences in frequency of universal/ARC MI

134 Charge depletion or accumulation resulted in substantial differences in friction force.

135 Ensemble kinetic experiments revealed substantial differences in fusion of this plasma membran

136 okaryotic genomes must take into account the substantial differences in gene content resulting from h

137 n in the absence of the bulb correlated with substantial differences in gene expression as compared t

138 Substantial differences in gene expression were observed

139 ous population, individual cells can exhibit substantial differences in gene expression, protein leve

140 Overall, despite substantial differences in genotyping technologies, mark

141 Statistical testing for substantial differences in ghrelin blood levels over tim

142 There are substantial differences in good outcome factors in CRVO

143 These perturbations reveal substantial differences in how ventral and dorsal cells,

144 There were substantial differences in indication for surgery betwee

145 ilar lability to photomineralization despite substantial differences in initial chemical composition.

146 Substantial differences in innate cytokine responses to

147 Substantial differences in intake of the other macronutr

148 Substantial differences in intakes and in sources of n-3

149 nza epidemics are highly synchronous despite substantial differences in intensity, and inclusion of n

150 the VC1:IIC2 protein complex, but there are substantial differences in interactions of base, fluorop

151 of highly conserved genes, yet we discovered substantial differences in intergenic length and species

152 nitial conditions prior to training leads to substantial differences in intermediate and higher-level

153 There are substantial differences in international guidelines for

154 hips for a single rate-determining step, and substantial differences in kinetic isotope effects for d

155 Despite substantial differences in kinetics of different antivir

156 e of ATP are much too small to explain their substantial differences in light scattering.

157 ity with various elliptical shapes, and with substantial differences in lipid ordering in the centre

158 ogeneity among influenza outbreaks including substantial differences in local outbreak timing and str

159 ay be responsible for regio-selectivity, and substantial differences in loop structures near the bind

160 Substantial differences in mean changes in drusen area,

161 a suite of edaphic characteristics, driving substantial differences in microbial community compositi

162 O were down-regulated in PC12 cells and find substantial differences in miR processing in the undiffe

163 We demonstrate substantial differences in morphological, molecular and

164 There were substantial differences in mortality rates and changes i

165 potassium were independently associated with substantial differences in mortality risk.

166 For snail kites, our method reveals substantial differences in movement strategies for diffe

167 These results reveal substantial differences in new neuron plasticity and fun

168 Such disparity helps to explain substantial differences in NK cell biology between human

169 However, there were substantial differences in observed vs. predicted mortal

170 Bioinformatics analysis reveals substantial differences in pathways involving Uba1- and

171 Due to substantial differences in patient characteristics betwe

172 differences in taxation) are associated with substantial differences in per capita healthcare expendi

173 troporation (IRE), Bulvik et al demonstrated substantial differences in physiologic, tumorigenic, and

174 We report substantial differences in predictive quality when these

175 After adjustment, there were no substantial differences in prevalence/risk of diagnosed

176 es match between the two regions but exhibit substantial differences in proportions and gene expressi

177 ternary complexes are very small, there are substantial differences in protein dynamics.

178 nriched in different amino acids can exhibit substantial differences in protein metabolism and functi

179 Substantial differences in protein profiles, abundance,

180 ilk, despite their independent evolution and substantial differences in protein structure.

181 reezing and storage of samples did not cause substantial differences in QVOA compared to use of fresh

182 To this end, we demonstrated that there are substantial differences in receptor binding and infectiv

183 sporter, ZnT3) and channel blockers revealed substantial differences in relevant Zn(2+) sources, with

184 udies of the same phenotype/phenomena create substantial differences in results.

185 Substantial differences in safety or immunogenicity betw

186 There were no substantial differences in sensitivity and specificity b

187 nes from two of the investigated clades, and substantial differences in sequence composition between

188 nd B6.SJL-CD45.1 congenic model, identifying substantial differences in SJL genetic content retained

189 We find substantial differences in specificity between lines tar

190 atistical methods of data analysis can yield substantial differences in study power.

191 However, this naive analysis ignores substantial differences in study quality and design.

192 Additionally, substantial differences in SUVmax intraindividually were

193 Bioinformatics analysis predicts substantial differences in targeting between miRNAs with

194 e methods reveal large-scale consistency but substantial differences in terms of small genomic rearra

195 over several orders of magnitude, suggesting substantial differences in the accessibility or electros

196 Monocytes, B cells, and T cells showed substantial differences in the activation of p38 and the

197 es of entire predicted proteomes demonstrate substantial differences in the amino acid-sequence prope

198 Our simulations showed substantial differences in the amount of buffelgrass on

199 There were systematic and substantial differences in the association between tempe

200 Although the enzymes share the same fold, substantial differences in the cavity of the catalytic s

201 Our data reveal substantial differences in the circulating antibody spec

202 We show that there are substantial differences in the composition of genotypes

203 Structural analysis revealed substantial differences in the contacts formed by the C-

204 The results indicate substantial differences in the covalent contributions to

205 of early-stage Parkinson's disease reported substantial differences in the development of these meta

206 Despite this structural similarity, substantial differences in the dimerization ability sugg

207 Using this system, we identified substantial differences in the downstream effects of SMA

208 to-protein spin diffusion experiments reveal substantial differences in the dynamics and hydration of

209 We discovered substantial differences in the dynamics of the inactive

210 Variation in flow resulted in substantial differences in the ecological response acros

211 Furthermore, no substantial differences in the efficacy and safety endpo

212 processes occurring within muscle, there are substantial differences in the expression of IFNalpha/be

213 Clinical observations have documented substantial differences in the extent of collateralizati

214 Despite substantial differences in the extent of the damage to t

215 There were no substantial differences in the fatty acid composition of

216 There were substantial differences in the firing behavior among int

217 We found substantial differences in the functional potential of M

218 Here, we uncover substantial differences in the GA transcriptomes between

219 There were more substantial differences in the genome-wide profile of H3

220 and analytical ultracentrifugation revealed substantial differences in the hydrodynamic behavior of

221 There were substantial differences in the influence of the two capp

222 We observed substantial differences in the inhibitory potency among

223 absence of structural information because of substantial differences in the interacting residues.

224 says with full-length Skp1 substrates reveal substantial differences in the kinetic properties of DdP

225 teriorly deformed in all three EG eyes, with substantial differences in the magnitude and extent of d

226 dose of infection or vaccination can lead to substantial differences in the magnitude and timing of A

227 rative untargeted metabolomics study to show substantial differences in the metabolic profiles of the

228 However, there were substantial differences in the micronutrient concentrati

229 Integrated molecular profiling showed substantial differences in the molecular features underl

230 Our analysis revealed substantial differences in the number and distribution o

231 the two virus discovery approaches revealed substantial differences in the number and types of virus

232 conditions are defined, but also because of substantial differences in the number of FEs composing t

233 n these statistical findings, we showed that substantial differences in the number of grandchildren,

234 The observed data indicate substantial differences in the PEP subsites and open the

235 There are substantial differences in the phase and structure behav

236 Our findings therefore reveal substantial differences in the primary sequences of prot

237 further suggest that there are likely to be substantial differences in the regulation of neuronal ex

238 ion, and glucose effectiveness, resulting in substantial differences in the regulation of postprandia

239 It also shows substantial differences in the relative abundance of vol

240 Comparison of the two structures reveals substantial differences in the relative positions of dom

241 The results reveal substantial differences in the role of prolyl and aspara

242 er this time scale are insufficient to cause substantial differences in the SID spectra of these comp

243 There were substantial differences in the socioeconomic/demographic

244 found, in the adult prefrontal cortex (PFC), substantial differences in the structure and connectivit

245 he lineage leading to mammals, together with substantial differences in the subcellular location of t

246 Despite substantial differences in the taxonomies (relative to 2

247 lants vs. 126 systemic therapies) because of substantial differences in the trajectories of VRQoL.

248 expression profiling of MCF7 cells revealed substantial differences in the transcriptome following t

249 There were no substantial differences in the utility scores between tr

250 tive sequences in potato and tomato revealed substantial differences in their abundance, 34.2% in pot

251 rm MS (FTMS) quantification, CE species show substantial differences in their analytical responses de

252 sequences and side chain chemistries lead to substantial differences in their observed interactions w

253 nd their derivatives in most cases; however, substantial differences in their odor threshold values w

254 ma1 and alpha/sigma2 hemicomplexes displayed substantial differences in their preference for particul

255 )-fold decrease in k cat/ K m) and also show substantial differences in their thermodynamic parameter

256 jor clades as the nuclear data but with some substantial differences in topology within the clades.

257 ittently cloudy day these would translate to substantial differences in total crop carbon assimilatio

258 und delays throughout ACS care, resulting in substantial differences in total times for women and old

259 tails of the additive allele score exhibited substantial differences in trait levels (e.g., >1 mmol/L

260 We find substantial differences in transcriptional frequency bet

261 This analysis identified substantial differences in tyrosine kinase signaling net

262 In nucleosome core particles (NCPs), we find substantial differences in UDG-directed cleavage at urac

263 ospital and intensive care unit stays reveal substantial differences in unit efficiency.

264 of care than white stroke survivors without substantial differences in unmet need.

265 virus A/Turkey/England/647/77 as defined by substantial differences in viral shedding trajectories.

266 se chromosomal disparities contribute to the substantial differences in virulence observed between th

267 gregate dietary changes were associated with substantial differences in weight change (3.93 lb across

268 Our analysis reveals substantial differences in wiring and gross anatomy betw

269 from 1988-1994 through 2009-2010, there were substantial differences in women.

270 r mean improvements in visual function, with substantial differences observed as early as month 1, in

271 The substantial differences observed supports the need for b

272 es more methylated than wild-type ones; this substantial difference occurred throughout the genome, w

273 anscytolemmal water-exchange can result in a substantial difference of MECVF, compared with assuming

274 tforward use of the Hertz model results in a substantial difference of the Young's modulus between th

275 However, there are substantial differences of opinion regarding the effecti

276 Substantial differences (P < 0.001) in transcript and ce

277 in China and several European countries, but substantial differences persist between countries, with

278 s of differentially regulated genes revealed substantial differences related to endoxifen concentrati

279 Because of the substantial differences shown among FNAB cases performed

280 e cell extracts with this probe, we observed substantial differences, stressing the importance for bi

281 h their host mRNAs, we observe a subset with substantial differences that suggest regulated processin

282 Notwithstanding these substantial differences, the data show that correlation

283 h pre- and post-chemotherapy samples do show substantial differences, the timing of the divergence is

284 A substantial difference up to 20% between coefficients in

285 No substantial difference was found between results obtaine

286 No substantial difference was noted in overall survival, an

287 In contrast, no substantial difference was observed in the acyl chain co

288 Substantial differences were found between clinical diag

289 No substantial differences were found between the scores of

290 No substantial differences were found in absolute lymphocyt

291 milarly complex binding characteristics, and substantial differences were noted between the PRDs from

292 domain of TLR10 with low sequence homology, substantial differences were observed at helices alphaC,

293 No substantial differences were observed between groups in

294 Substantial differences were observed in the ability of

295 No substantial differences were observed in the distributio

296 Substantial differences were seen between patient subgro

297 starvation for different nutrients and found substantial differences: When deprived of leucine or ura

298 The structures reveal substantial differences, which shed light on the complex

299 The results show substantial differences with respect to the mature fibri

300 Worldwide there are substantial differences within and between countries in