ライフサイエンスコーパス: substitute

1 1M) with F160M/M184V (L180M/M204V in HBV RT) substituted.

2 bility and hemodynamics comparable to tissue substitutes.

3 C3-substituted 1H-indazoles are useful and important substr

4 t-dependent manner whereas difluoromethylene-substituted 1H-isochromen-1-ones are generated under the

5 nt synthetic route to access enantioenriched substituted 2,3-dihydro-1H-pyrrolizin-1-ones.

6 acile access to a single regioisomer of N(1)-substituted 2-aminobenzimidazoles as well as fused tetra

7 rotocol enabled the C-H functionalization of substituted 2-methylquinolines with diacetyl or ethyl py

8 a a Ritter initiated cascade provides highly substituted 2-oxazolines in high yields.

9 Considering N-substituted 2-pyridone acts as a biologically-active str

10 Substituted 2-pyridone ligands were found to be key in a

11 hosphinines, starting from a 3-N(CH(3) )(2) -substituted 2-pyrone and (CH(3) )(3) Si-C=P.

12 F(4) (-) , CMOM-2S) or mandelate ligands are substituted (2-Cl, CMOM-11R; 3-Cl, CMOM-21R; 4-Cl, CMOM-

13 A collection of 42 novel alkyl 4-substituted-2-methyl-1,4-dihydrobenzo[4,5]imidazo[1,2-a]

14 rticular, some of the obtained perfluoroaryl-substituted 2H-imidazoles were found to be of particular

15 d for the regioselective synthesis of 2-aryl-substituted 2H-indazoles is reported.

16 20 degrees C in a sealed tube delivers the 2-substituted-2H-indazoles in a single synthetic step with

17 Even conservatively substituted 3'-amino nucleotides generally act as chain

18 Here, differently 8-substituted 3-arylcoumarins are complementarily studied

19 ng pyrroloisoquinolone, leads to variously 5-substituted 3H-pyrrolo[2,3-c]isoquinolines in excellent

20 s to provide the corresponding 2-aryl(alkyl) substituted 4-(trifluoromethyl)quinolin-3-ylphosphonates

21 for the synthesis of 3-[(4-nitrophenyl)thio]-substituted 4-methylene-1-pyrrolines is described.

22 eloped to afford over 80 novel ring-fused, N-substituted 4-quinolinones, an underrepresented privileg

23 , Cr, Fe, Ni...; Y = O, NR, CH(2), S), i.e., substituted 5-azabicyclo[3.3.3]undecans.

24 A wide variety of N-substituted 7-amino coumarin analogues was prepared in g

25 An efficient access to 6-substituted 7-deazapurine and the corresponding nucleosi

26 elices in the transport function of P-gp, we substituted a group of 14 conserved residues (seven in b

27 Using only proline catalysis, heteroaryl-substituted acetaldehydes are fluorinated and then direc

28 The treatment of mono-substituted activated arenes led to para-brominated prod

29 loped, enabling efficient synthesis of alkyl-substituted acylsilanes in high yield.

30 of synthetically highly versatile metalloid-substituted alkenes, which are key building blocks on ro

31 d, length as m-dash]C, SiH) and alpha-di-SiH-substituted alkynes (hetero-tri-functional: SiH, C[tripl

32 We used triisopropyl silane-substituted alkynes for the alkynylation reaction, which

33 Trityl-substituted alkynylpyridines 3-5 react with Pd(II) to fo

34 More specifically, Z-chloro-substituted allylic pinacolatoboronate is first obtained

35 ctical approach for the synthesis of N(beta)-substituted alpha,beta-diamino acids, such as 1-isohisti

36 -hydride addition to the alkene, to the more substituted alpha-carbon is 3.6 kcal/mol lower than that

37 nspire new retrosynthetic disconnections for substituted amine derivatives in organic synthesis, and

38 ctionalized isocyanobenzoates and a range of substituted amines, although the use of aromatic amines

39 For example, the OH stretch of an amino-substituted analogue is red-shifted by roughly 50 cm(-1)

40 Unlike the methyl-substituted analogue, the phenyl analogue exhibits a dua

41 with the formation of carbocation 6 and its substituted analogues correlates with the C-H arylation

42 1-Substituted and 1,1-disubstituted tetrahydro-beta-carbol

43 tion) provided access to a wide variety of 2-substituted and 2,3-disubstituted pyrroles from the avai

44 ilyl bromide (TMSBr) to a broad variety of 3-substituted and 3,3-disubstituted oxetanes.

45 nantioselective synthesis of trifluoromethyl-substituted and aryl-, heteroaryl-, alkenyl-, and alkyny

46 Tea, coffee, chocolate, spinach, infant milk substitute) and battery wastewater.

47 ication in medicinal chemistry programs as p-substituted aniline bioisosteres.

48 rature, protecting-group-free oxidation of 2-substituted anilines has been developed to generate an e

49 A method for the synthesis of 2,3,6,7-substituted anthracene derivatives, one of the most chal

50 A broad scope with all six-carbon-substituted arene motifs, control experiments, and gram-

51 quence, the selectivity of the silylation of substituted arenes is generally governed by ligand-subst

52 tution and heteroaromatic and hindered ortho-substituted arenes on the azomethine ylide.

53 C-H bond of symmetrically and asymmetrically substituted arenes to form silylated arenes and to regen

54 e cross-coupling to generate complex, highly substituted arenes.

55 nzamides with 1,5-enynes to access diversely substituted aromathecin derivatives involving C-H activa

56 We examined the substrate scope using substituted aromatic and aliphatic derivatives.

57 o-phenylenediamine/substituted diamines and substituted aromatic/heterocyclic/aliphatic aldehydes un

58 ns a phosphine ligand bearing trimethylsilyl-substituted aryl groups and a triflimide counteranion, a

59 speroxidation of sterically hindered various substituted arylidene-9H-fluorene/arylideneindolin-2-one

60 t complex ETPs equipped with a strategically substituted azide functional group are readily derivatiz

61 NH moieties were replaced, the former with a substituted aziridine moiety and the latter with an NCO-

62 are developed to selectively obtain 4- and 5-substituted azulenes based on the nature of bases and nu

63 ide access to several different classes of 1-substituted azulenes, including a conjugated ketone and

64 e precursor for selective formation of bromo-substituted B,N,B-benzo[4]helicenes 2 a/2 b via intramol

65 ibbons (GNRs) that contain site-specifically substituted backbone heteroatoms is one of the essential

66 namely ground coffee, soluble coffee, coffee substitutes, barley, cow milk, vegetable drinks, tea, pl

67 he latter and a gem-dimethyl, beta-ketoester-substituted BC dihydrodipyrrin afforded the enone (E, 70

68 his gives entry to the synthesis of multiply substituted BCP triazoles on either a modular or a one-p

69 vides ready access to a broad range of ortho-substituted benzamides.

70 hod is amenable to a range of differentially substituted benzyl alcohols, benzylamines and aniline an

71 The diastereoselective synthesis of highly substituted beta-lactams by intramolecular Tsuji-Trost a

72 neindolin-2-one derivatives to afford highly substituted bisperoxides with high selectivity over the

73 Interestingly, a CF(3)-substituted BODIPY, known for forming J-type aggregates,

74 l robotic liquid transfers of a common blood substitute by their endothelium-lined channels (as repor

75 Cyclohex-2-enones substituted by a 2'-propenyloxy, 2'-butenyloxy, 2'-pente

76 3)) surprisingly furnish an aminophosphonium substituted by a zwitterionic indazole.

77 n the Asp and Glu residues in the motif were substituted by alanine.

78 of evidence the human mucus can be reliably substituted by animal counterparts for human-relevant tr

79 om and the phosphate group were successfully substituted by means of the reaction with the organozinc

80 Some substituted C8 PFSAs [keto-perfluorooctane sulfonate (PF

81 re made possible by a self-assembled, methyl-substituted carbazole monolayer as the hole-selective la

82 ble carbocyclic scaffolds can yield uniquely substituted carbocycles that would be challenging to con

83 ew methods are available that can link fully substituted carbon atoms of two rings with stereocontrol

84 Stereogenic trifluoromethyl-substituted carbon centers are highly sought-after moiet

85 symmetric construction of C-O bonds at fully substituted carbon centers in the synthesis of chiral 2,

86 Ozonides with para-substituted carboxymethoxy and N-benzylglycine substitue

87 lesser crowding of the di-isopropylphosphino-substituted catalysts.

88 the chlorination of phenol, para- and ortho-substituted chlorophenols (2-Cl, 4-Cl, 2,4-diCl-, 2,6-di

89 and efficient synthetic routes toward 3-acyl-substituted chromones ranging from readily available chr

90 ed spongian diterpenoids harboring a concave-substituted cis-2,8-dioxabicyclo[3.3.0]octan-3-one fragm

91 helating and donating properties of an ortho-substituted closo-carborane (1,2-(Ph(2)PO)(2)-1,2-C(2)B(

92 is also found that the di-isopropylphosphino-substituted complexes catalyze dehydrogenation of severa

93 Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorinat

94 It is found that the partially substituted Cu(x) In(1-x) NNi(3) possesses a thermal neu

95 fluorophore is composed of a triphenylamine-substituted cyanostar macrocycle, and it exhibits a rema

96 tane was efficiently synthesized from a mono-substituted cyclobutane through sequential C-H arylation

97 xperimental side, the hydride reduction of 3-substituted cyclobutanones was proven to be highly selec

98 ed, and evaluated a novel series of fluorine-substituted cyclohexene analogues, thereby identifying 8

99 ss-[4+4]-cycloaddition of 1,3-dienes to form substituted cyclooctadienes under very mild conditions.

100 ows for the efficient formation of diversely substituted cyclopentanes as well as the construction of

101 Cloke-Wilson-type ring expansion of the aryl-substituted cyclopropane carbaldehydes with the hydroxyl

102 consistent with the topology obtained by the substituted cysteine accessibility method and revealed t

103 We further showed that substituting delivery vans with electric cargo bikes can

104 of the linkers and the barrier for isopropyl-substituted derivative 10 was experimentally estimated t

105 Working with a model, a pentamethyl-substituted derivative, we found that the mutual orienta

106 nce spectroscopy reveals that the anthracene-substituted derivatives fluoresce poorly (Phi < 0.01).

107 to accompany these reactions, the anthracene-substituted derivatives resist direct photoinduced oxida

108 ybenzyl-, and alpha-3,4-dihydroxybenzylidene-substituted derivatives, exhibited complex and varying s

109 t rapid nonradiative decay of the anthracene-substituted derivatives, perhaps because of inter-arene

110 ntense Cotton effects are observed for ortho-substituted derivatives, which undergo a rapid decomposi

111 Substituting DHA with another oil noticeably reduced the

112 catalyze the coupling of o-phenylenediamine/substituted diamines and substituted aromatic/heterocycl

113 A series of substituted diarylazetidines were readily prepared and i

114 d alpha,beta-unsaturated esters, beta-indole-substituted diazo esters, and dienes are obtained with g

115 ctivity relationship assays using additional substituted dichlorophenes identified key moieties neede

116 We conclude that symmetrically substituted dichlorophenes potently inhibit NAPE-PLD in

117 potent (IC(50) = ~2 mum) being symmetrically substituted dichlorophenes, i.e. hexachlorophene and bit

118 RCTs) investigating the isocaloric effect of substituting dietary sugars (fructose, glucose, sucrose)

119 ary route employs reaction of a gem-dimethyl-substituted dihydrodipyrrin-carboxaldehyde (AD half) and

120 densation of Asmic with imines to generate N-substituted dihydroimidazoles.

121 e route for the synthesis of 3-diarylmethine substituted dihydropyrroles, in one pot.

122 violet neutral complexes, which carry an EWG-substituted dinegatively charged catecholate ligand.

123 he steric demand of the electron-rich, alkyl-substituted double bond determines the reaction pathway,

124 ant transition metal borides are emerging as substitute electrochemical hydrogen evolution reaction (

125 metallacycle becomes possible when an alpha-substituted enoate is used.

126 der mild aqueous and basic conditions, alpha-substituted enone-aldehydes and 1,3-carbonyls undergo a

127 m-dash]C) in Cp'2M(eta2-Me3SiC2SiMe3) (Cp' = substituted eta5-cyclopentadienyl), of alpha-di-Ph2P- (h

128 The less reactive 2-substituted ethynylphosphonates required gold complexes

129 plasticity and alternative interactions that substitute for absent conserved motifs.

130 Use of claims to substitute for adjudicated outcomes in traditional trial

131 urthermore, we demonstrate that Netrin-1 can substitute for blockade of Gsk3alpha/beta and Mek1/2 to

132 ; furthermore, biomass ashes were a suitable substitute for CEM 1 up to 50% w/w.

133 ependence and also serve as a noncombustible substitute for cigarettes.

134 nd cell expansion but that cell division can substitute for endoreplication without affecting final o

135 aenoic acid (DHA)-rich Schizochytrium sp. as substitute for fish oil.

136 e public views telemedicine as an acceptable substitute for in-person visits, especially during the p

137 opment of two distinct FGF23 assays that can substitute for invasive bone biopsies to infer the activ

138 k has indicated that other metal cations can substitute for Mg(2+), raising questions about the role

139 ndicate that while social media do not fully substitute for on-site data, they are a powerful compone

140 e as an efficient preliminary, auxiliary, or substitute for panCK IF by delivering virtual panCK IF i

141 we study how local adrenergic activation can substitute for the Reissner fiber-signaling pathway to C

142 and rice flours, and WPC could be used as a substitute for wheat flour in producing sponge cakes of

143 d in which aspartic acid in position 163 was substituted for asparagine (the most common in prion sus

144 Rice straw was substituted for sawdust at five different ratios of 0, 2

145 tomatitis viruses with the EBOV glycoprotein substituted for the VSV glycoprotein show greater safety

146 op, which harbors a Zn(2+)-binding site that substitutes for a loop-stabilizing disulfide bond.

147 the role of hypoxia mimetics as experimental substitutes for hypoxia and provides new findings on HIF

148 ore specifically, we report the synthesis of substituted forms of model system 1 to study the effects

149 The T(1) and S(1) states of most substituted fulvenes (159 of 225) are described by singl

150 r the preparation of phosphorus and fluorine substituted gamma-lactam derivatives is presented.

151 Substituting Ge for Sn weakens the {Ge,Sn}-S bonding int

152 Soft tissue substitutes have been proposed to replace autogenous con

153 alize the different reactivities of O- and S-substituted heteroallenes.

154 roducts including sterically demanding ortho-substituted heteroarenes.

155 elds ranging from 15 to 85% for a variety of substituted heterocycles.

156 sed gamma-lactam formation across a range of substituted heterocycles.

157 nd aryl-, heteroaryl-, alkenyl-, and alkynyl-substituted homoallylic alpha-tertiary NH(2) -amines is

158 sis to show that all-syn contiguously methyl-substituted hydrocarbons, with chain lengths from C6 to

159 N), leading to the selective formation of C3-substituted imidazo[1,2-a]pyridines, an heterocyclic moi

160 tic imidazolate frameworks (ZIFs) based on 2-substituted imidazolate linkers.

161 Orteronel (TAK-700) is a substituted imidazole that was developed for the treatme

162 yme, glycogen synthase (GS), we identified a substituted imidazole, (rac)-2-methoxy-4-(1-(2-(1-methyl

163 ctive and fully selective, leading to 3-aryl-substituted imidazopyridines in moderate to high yields

164 We find that each substituted In impurity introduces a striking localized

165 d selectivity and showed that while the C(3)-substituted indoles are selective, high affinity NOP lig

166 oselective intermolecular C2-allylation of 3-substituted indoles is reported for the first time.

167 The allylations of different substituted indoles proceed with negligible diastereo- a

168 simple, allowing borylation of a variety of substituted indoles with B(2)pin(2) in excellent yields

169 The synthesis of variously substituted indolo[2,3-c]quinolin-6(7H)-ones was develop

170 and s(N) of the reference nucleophiles were substituted into the correlation log k(2)(20 degrees C)

171 A 2D array of bismuth-substituted iron-garnet nanopillars on an ultrathin iron

172 ether and to which extent virgin material is substituted, is insufficient for evaluating the transiti

173 sation of MeP(SiMe(3))(2) with a series of 5-substituted isophthaloyl chlorides (5-R'C(6)H(3)-2,6-{C(

174 minants of SAM domain function in SAMD14, we substituted its SAM domain with distinct SAM domains pre

175 1-keto macrocyclic systems, as well as two N-substituted ixabepilone analogues in which the 12,13-epo

176 r enantioselective hydroboration reaction of substituted ketones, and the corresponding secondary alc

177 eta-keto esters led to the biosynthesis of 6-substituted l-pipecolates.

178 The article concluded that the extract substitutes leaves in bread as a product of a high benef

179 carbene-metal-amide photoemitters with CF(3)-substituted ligands to show sky-blue to deep-blue photol

180 presents a series of four new diarylethynyl-substituted long acenes-three tetracenes and one anthrad

181 Unexpectedly, SETD3 was active on the substituted methionine, generating S-methylmethionine in

182 hose counted as "undocumented" at arrest and substituting misdemeanors or convictions as measures of

183 well as DFT calculations on a sulfoximinoyl-substituted model system to explain the pronounced solve

184 The iron atoms substitute molybdenum sites in MoS(2) crystals, as confi

185 acid, MAR reduced only one double bond in 3-substituted muconic acids.

186 We herein reported a series of novel substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydrox

187 d(II)-catalyzed C-H alkenylation reaction of substituted N-allylanilines via an unusual 6-endo proces

188 pot procedure for the preparation of 2-alkyl-substituted N-arylindoles is described.

189 gic acid diethylamide (LSD), psilocybin, and substituted N-benzyl phenylalkylamines are widely used r

190 The fluorescent nature of core-substituted naphthalene diimide monomers has been furthe

191 ty would be attained and the resulting alpha-substituted NH-ketimines, wherein there is strong C=N ->

192 vide alpha-aryl and alpha-alkyl alpha-methyl-substituted nitriles, respectively.

193 oducts that are unified by the presence of a substituted, nitrogen-containing heterocycle core.

194 , and Na(v)1.5 is inactive at 10 mum We also substituted noncoded amino acids at select positions in

195 st that this technology could be a promising substitute of traditional lab-based techniques for the d

196 e key building blocks on route to all-carbon substituted olefins.

197 the instantaneous current-voltage curve, and substituting one or two residues in the selectivity filt

198 We thus substituted only climate sensitivities when projecting f

199 Optimized geometries for the substituted ortho-benzyne as well as harmonic vibrationa

200 However, substituting oxygen in the phosphodiester backbone with

201 hotophysical studies reveal that the Bu(3)Sn-substituted PAHs are moderately fluorescent, and their p

202 In addition, mono-substituted patulin-glutathione adducts were identified

203 ine Greek cross (+)-assembly of 6,13-bisaryl-substituted pentacene derivatives.

204 stereoselective synthesis of unsymmetrically substituted pentafulvenes is reported via the condensati

205 morphous phase transitions of prepared 1,3,6-substituted pentafulvenes showed the expected reversible

206 Using this dually reactive alkylamine-substituted perthiocarbamate platform, the generation of

207 cid derivatives, 3-arylpiperidines, or other substituted phenethylamines.

208 the para-substituted phenol radical-cations and the corresponding

209 Hydroxylation of substituted phenols by flavin-dependent monooxygenases i

210 Probing the reactivity of substituted phenols toward the nitritocopper(II) cryptat

211 The binding constants (K(b)) of the para-substituted phenols with the surfactant were also measur

212 The presence of polar co-adsorbates, such as substituted phenols, enhances the hydrogenation rate of

213 photooxidation of a number of asymmetrically substituted phenyl azides in acetonitrile was studied.

214 stituent on the N-tert-butyl moiety and para-substituted phenyl or naphthlyl moieties were synthesize

215 flexible precursors for a variety of highly substituted phosphoarenes, and in situ downstream functi

216 trategy for the straightforward synthesis of substituted phthalimides is described, which includes ba

217 Di-isopropylphosphino-substituted pincer-ligated iridium catalysts are found t

218 dopting a sharp kink, and its N-CF(3)-phenyl substituted piperazine group reaching out to the far sid

219 A novel series of C(3)-substituted piperdinylindoles were developed as nocicept

220 alpha-amino C-H arylation reaction of highly substituted piperidine derivatives with electron-deficie

221 rational intermolecular cyclocondensation of substituted piperidines with arylaldehydes provides dive

222 y, which serve as useful building blocks for substituted piperidines.

223 imes, and recent conceptual breakthroughs in substituting precious and rare-Earth metal ions (e.g. Ru

224 (3)H]PSB-1584) by hydrogenation of a hexenyl-substituted precursor with tritium gas.

225 can be directed towards either tin- or iodo-substituted product formation, giving complementary choi

226 Additionally, substituted products are from fisheries with less effect

227 We substituted protein-rich defatted biomass of Nannochloro

228 d apparent RNA-binding affinity of the N196K-substituted protein.

229 In addition, 8-p-anisyl-5-p-cyanophenyl-substituted psoralen exhibits aggregation-induced emissi

230 were performed on a series of bicyclic C(2)-substituted pyranoside models to isolate and analyze fac

231 profile that led to the identification of a substituted pyrazole, 4-(4-(4-hydroxyphenyl)-3-(trifluor

232 products were obtained in three steps from a substituted pyridine-2-carboxaldehyde prepared from comm

233 dichloride complexes having a bis-ferrocenyl-substituted pyridinediimine ligand was systematically sy

234 r differences in reactivity between 2- and 3-substituted pyridines.

235 les to provide access to a variety of highly substituted pyridines.

236 Phenethyl derivatives in position 9, substituted pyridyl moieties in position 4 and small alk

237 es connected to oxazole, imidazole, or nitro-substituted pyrrole.

238 14, pK(aH) 12.6) and the 2-imidazoliummethyl-substituted pyrrolidine A21 (pK(aH) 11.1) are outside th

239 ination to furnish 1,2,3-dihydrotriazole and substituted pyrrolidine products, respectively.

240 fication of the potent antitubercular 2-thio-substituted quinazolinone 26.

241 sors has granted the formation of a range of substituted quinolinoquinolines.

242 inary biomarker panel, which was improved by substituting REG1A with REG1B.

243 The additional Lys residue was introduced by substituting residue locating on the surface of AvLOx, a

244 By substituting residues in the C. punctatum PHD with the c

245 The reaction is tolerant of 2-substituted resorcinols (R' = OH, Cl, Br, Me), allowing

246 as an unprecedented structure comprised of a substituted resorcylaldehyde headgroup linked to a 15-ca

247 The phenylimine-substituted rhodium complex (eta(5)-C(5)Me(5))Rh((Me)PhI

248 ed allylic substitution of challenging alkyl-substituted secondary allylic carbonates with benzylzinc

249 tilization of an electron-deficient difluoro-substituted secondary amine catalyst and the intrinsic r

250 ates of cyclobutadiene-fused troponimines by substituting several electron donors along with the chan

251 ound that this activator, the bromothiophene-substituted small molecule GAT1508, is specific for brai

252 The di-t-butylphosphino-substituted species are ineffective for such substrates;

253 f the tridimensional compounds in heteroatom-substituted species.

254 the previously reported di-t-butylphosphino-substituted species.

255 re, however, limited to diamino- and dialkyl-substituted species.

256 fect (NOE) measurements of an asymmetrically substituted squaramide and its thio analogue are consist

257 able of simultaneously monitoring all singly substituted, stable isotopic variants of N(2)O.

258 borrowing reaction enabled the formation of substituted stereo-defined cyclopentanes from Ph* methyl

259 etric Wagner-Meerwein rearrangements of beta-substituted styrenes are catalyzed by the C(2)-symmetric

260 t enantioselectivity is achieved even with o-substituted substrates, which are particularly challengi

261 lcohols to complex cyclic systems and highly substituted sugar derivatives.

262 unctionalized nitroalkenes affords diversely substituted sulfonylfurans and dihydrofurans.

263 s can all be achieved from the appropriately substituted tertiary amines.

264 The substituted tetrahydropyrroloisoindolone can be converte

265 tion has been developed for the synthesis of substituted tetrahydropyrroloisoindolone via Mannich rea

266 We substituted the N-terminal eight residues of FP (FP8, re

267 To examine the CD origin, we have substituted the retinal chromophore of gR by synthetic r

268 introduce ReQTL, an eQTL modification which substitutes the DNA allele count for the variant allele

269 eport that sulfite anion radical efficiently substitutes the three carboxyl moieties of Finland trity

270 e also chemically modified these aptamers by substituting their 2'-OH group with 2'-fluorine.

271 discontinuation PTX with doxorubicin as the substitute, there was no further progression of her LSCD

272 Nebulosins feature an unprecedented highly substituted thiolane ring leading to up to four contiguo

273 s modular building blocks to generate richly substituted, three-dimensional compounds.

274 ently fluidically coupled via a common blood substitute through their reservoirs of medium and endoth

275 otal folate content, which could be a proper substitute to the currently standardized but imprecise a

276 egenerately doped ZnO is seen as a potential substitute to the ubiquitous and expensive Sn doped In(2

277 ost likely decreases the GHG footprints when substituting traditional shopping, while FMCGs purchased

278 e, we consider a series of emitters based on substituted triarylamine (TAA) donors and a radical-carr

279 roviding access to 4-, 1,4-, 1,5-, and 1,4,5-substituted triazoles in excellent yield.

280 Substituted triphenylamine (TPA) radical cations show gr

281 A range of substituted triphenylethylene synthetic estrogens and di

282 todextrin (13.5% w/w dry matter) and totally substituting Tween(R)20 with MC.

283 determine the influence of wild-type or S34F-substituted U2AF1 on the conformational dynamics of U2AF

284 tion by the RECODe equations was improved by substituting VA-specific coefficients (C statistic incre

285 Its substituted variants, however, have been less carefully

286 cluster-adjusted model, the use of the salt substitute was associated with a 51% (95% CI (29%, 66%))

287 ng a bioabsorbable membrane and a bone graft substitute with at least 1-year follow-up were included.

288 , we generated mutant mice in which Ser21 is substituted with alanine (GRK1-S21A), preventing dark-de

289 luoromethyl-bearing quaternary stereocenters substituted with alkenes, alkynes and ketones.

290 ed the RGT, except basiliximab induction was substituted with CBMPs and mycophenolate mofetil taperin

291 Reactions performed using GTP analogs substituted with different chemical moieties at the 2' p

292 ich E and D residues in the MERS-CoV FP were substituted with neutrally charged alanines (A).

293 (LTAs) with poly-(beta1->4)-ManNAc backbones substituted with phosphoethanolamine.

294 one of the three sulfo groups can be easily substituted with S-, N-, and P-nucleophiles, opening acc

295 r, in the crystal, the triarylmethanol, para-substituted with the chiral moiety, shows a propensity f

296 o spaghetti and a commercial bread flour was substituted with WBPC at 0, 1, 5 and 10% w/w and made in

297 Semolina was substituted with WBPC at 0, 1, 5, 10 and 20% (w/w) and m

298 The lack of tissue substitutes with mechanical and biological properties si

299 of different guest atoms may potentially be substituted within Type-VII clathrate cages, presenting

300 may contain an alkyl-, a chloro-, or a bromo-substituted Z-alkene, can either be purchased or prepare