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1 n for every 40-50 molecules of free protein (substoichiometric).
2 PSII complex, whereas PsbP is significantly substoichiometric.
3 ng in the proteins as isolated varies and is substoichiometric.
7 d betaE(199)V/Y(345)W subcomplexes hydrolyze substoichiometric [(3)H]ATP, whereas it is not retained
10 ble than IAPP homodimers, which explains the substoichiometric ability of HNG to inhibit amyloid grow
11 ion of the APC requires its association with substoichiometric activating subunits termed Cdc20 and H
12 ow that GrB enzymatic activity still induces substoichiometric activation of caspases, which through
13 ts, an inexpensive ligand and Ni source, and substoichiometric AgNO(3), proceeding at room temperatur
16 concluded that although cyt cy is present in substoichiometric amount compared to the RCs, it support
17 ne via intramolecular azo annulation using a substoichiometric amount of 1,8-diaza-bicyclo[5.4.0]unde
18 a fluorinated aluminum salph complex with a substoichiometric amount of a nucleophilic cocatalyst.
21 ents in conjunction with a stoichiometric or substoichiometric amount of chiral controller to deliver
24 ET domain-containing HMTs MLL3 and MLL4, and substoichiometric amount of JmjC domain-containing putat
26 formation is catalytic in electrons; i.e., a substoichiometric amount of reduced species can isomeriz
30 coupling (CDC) reaction with aldehydes using substoichiometric amount of TBAB (tetrabutylammonium bro
31 "activated" through mono demethylation by a substoichiometric amount of the borate, [PhNMe(2)H][B(C(
32 rination alternative using Selectfluor and a substoichiometric amount of triethylborane--an establish
33 ruthenium photocatalyst in the presence of a substoichiometric amount of triphenylphosphine upon irra
34 stoichiometric amounts of Bronsted acids or substoichiometric amounts (20 mol %) of Lewis acids is a
35 ase (EcPhr), the MTHF cofactor is present in substoichiometric amounts after purification, while in V
36 type, suggesting that Cox11p is required in substoichiometric amounts for its role in oxidase assemb
37 ons in both 16S and 23S rRNA were present in substoichiometric amounts in the preribosomal particles.
38 mixing six different dipyridyl ligands with substoichiometric amounts of [Pd(CH(3)CN)(4)](BF(4))(2).
39 ow temperature (-78 degrees C), and requires substoichiometric amounts of a simple copper(I) or coppe
42 magnetic resonance, we provide evidence that substoichiometric amounts of annexin A5 inhibit h-IAPP a
44 by dithiothreitol (DTT), the enzyme contains substoichiometric amounts of calcium and zinc but little
48 ipoprotein/lipopeptide nonresponsive; and 2) substoichiometric amounts of deacylated LPS that block L
52 nt of 402.1 +/- 35.1 nM, and that binding of substoichiometric amounts of FAD triggers a transition i
53 DvFtn) and its E130A variant was loaded with substoichiometric amounts of Fe(2+), and the products we
56 urface-immobilized fibronectin, we show that substoichiometric amounts of heparin exposed cryptic VEG
58 he vast excess of insulin over IAPP in vivo, substoichiometric amounts of insulin inhibit seeded and
59 r equivalents of calcium and zinc along with substoichiometric amounts of iron and functions as a ure
60 D, purified from Escherichia coli, contained substoichiometric amounts of iron and had an absorption
63 r(CO)(2)I(3)(COMe)](-), 6, is accelerated by substoichiometric amounts of neutral promoter species (e
64 s obligate heteropolymers requiring NF-L and substoichiometric amounts of NF-M and/or NF-H, NF invest
66 l complex of variable length, perhaps due to substoichiometric amounts of other CASCADE components.
67 assembly/disassembly reactions revealed that substoichiometric amounts of PrABP80 can nucleate actin
68 amethyldisilazide), Mg(HMDS)(2), reacts with substoichiometric amounts of propiophenone in toluene so
69 n between PrP(C) and Abeta and discover that substoichiometric amounts of PrP(C), as little as 1/20,
71 of SmI(2) as a catalyst in combination with substoichiometric amounts of Sm(0); the latter likely ac
72 n of Tet-v2.0-protein reacts in cellulo with substoichiometric amounts of sTCO-label fast enough to r
73 ated A subunit association with membranes at substoichiometric amounts of the B subunit or the 16-kD
77 pentamers on a T=7 icosahedral lattice, with substoichiometric amounts of the minor capsid protein, L
78 mild conditions expedited by the presence of substoichiometric amounts of thiourea additives is prese
80 lysis as well as poisoning experiments using substoichiometric amounts of various poisoning agents.
81 strength polymerization-promoting F-buffer, substoichiometric amounts of VT accelerate the polymeriz
82 lopropylmagnesium bromide in the presence of substoichiometric amounts of zinc bromide produces cyclo
83 w that, under near-physiological conditions, substoichiometric amounts of Zn(2+) effectively retard t
85 presence of the high affinity ligand GM1 (at substoichiometric amounts relative to binding sites) in
86 Additionally, the hydrazine can be used in substoichiometric amounts relative to the aldehyde chain
87 longation/secondary nucleation when added in substoichiometric amounts with D76N-beta(2)m monomers.
88 subunits ABCDEFGH (with subunit C present at substoichiometric amounts) as determined by matrix-assis
89 ntrast SEK can activate SAPK when present in substoichiometric amounts, but this activation is slow,
92 (either free base or metalated) to E287Q is substoichiometric, as this variant retains bound porphyr
96 a simple iridium catalyst in the presence of substoichiometric base without an excess of reagents.
97 ns increase the final anisotropy of actin at substoichiometric binding densities, indicating long-ran
100 with a KI of 45 +/- 7 microM, also exhibited substoichiometric binding to 3 +/- 1 sites per hexamer,
102 elated AAV1 and AAV6, a common Fab exhibited substoichiometric binding, with one Fab bound, on averag
104 dissociation of RT dimer is responsible for substoichiometric burst amplitudes with normal substrate
105 -dihydroguanine (8-oxoGua) moieties in which substoichiometric bursts (2-35%) were observed even afte
106 verse transcriptase (HIV-1 RT) have reported substoichiometric bursts (30-50%) of product formation i
107 in normal nucleotide incorporation and that substoichiometric bursts with modified systems are well-
109 w-abundance proteins that are susceptible to substoichiometric carbonylation during oxidative stress.
110 e is a helical filamentous assembly in which substoichiometric CARMA1 nucleates Bcl10 filaments.
111 azapyrenium-based metallacycle as a reusable substoichiometric catalyst for the SNAr reaction between
112 the key functional and pathological roles of substoichiometric chaperones in prion-like propagation.
114 a binding-induced rate enhancement, enables substoichiometric chirality transfer from the receptor t
118 standard NMR-exchange measurement to detect substoichiometric complexes overcomes this time scale li
119 ith Ltv1, a protein recently identified as a substoichiometric component of a 43S preribosomal partic
121 l for rapidly identifying stoichiometric and substoichiometric components of large protein assemblies
123 o sCD14 was very slow but was accelerated by substoichiometric concentration of LBP, and the rate of
127 bly of each corresponding polypeptide at low substoichiometric concentrations (1:10 gammabody:monomer
128 y and that these chaperones are effective at substoichiometric concentrations (approximately 1:50).
129 ro, CsgC inhibited CsgA amyloid formation at substoichiometric concentrations and maintained CsgA in
130 hibits the aggregation of alpha-synuclein at substoichiometric concentrations and that binding occurs
133 inhibited at center P and preincubated with substoichiometric concentrations of antimycin showed a r
134 hat CaM binding to the MLCK enzyme begins at substoichiometric concentrations of Ca2+ (< or = 2 mol o
135 , with the same technology, we observed that substoichiometric concentrations of clusterin prevent ol
138 hen dealing with tight-binding inhibitors if substoichiometric concentrations of inhibitor are preinc
139 f lithium diisopropylamide (LDA) solvated by substoichiometric concentrations of oxetane, THF, Et(2)O
141 vitro assembly was efficiently inhibited by substoichiometric concentrations of purified Hsp70 in th
142 embly in the presence of both saturating and substoichiometric concentrations of the 44/62 protein.
145 le nature provides a platform to coeliminate substoichiometric concentrations of various salts throug
146 nds selectively inhibited oligomerization at substoichiometric concentrations relative to amyloid bet
147 ) stimulates Rad51-mediated recombination at substoichiometric concentrations relative to Rad51.
148 blue inhibited oligomerization when used at substoichiometric concentrations relative to that of the
149 n of full-length, four-repeat tau protein at substoichiometric concentrations relative to total tau a
151 n the electron donor formate was supplied at substoichiometric concentrations, the interactions betwe
153 tions and substantially delay aggregation at substoichiometric concentrations, while homodivalent lin
164 tween the QB-depleted enzyme and UQ2H2 under substoichiometric conditions, there was no observable ch
166 l ions; this component is also detected as a substoichiometric consitutent of the purified T4MOH.
169 not burn, while CuO/RF composites, even with substoichiometric CuO, sustain combustion, burning compl
172 ent to inhibitory therapeutics, facilitating substoichiometric dosing that does not require an active
176 tightly associated with the proteasome in a substoichiometric fashion, e.g., the deubiquitinating en
177 nation of single-molecule photobleaching and substoichiometric fluorescent labeling to determine the
178 ults in a 1000- to 2000-fold change, so that substoichiometric forms are estimated at less than one c
179 Oxidation also leads to the appearance of a substoichiometric free radical EPR signal with an averag
181 ear relationships between rate and [H(2)] at substoichiometric [H(2)] with rate law orders of 0.66 +/
182 C52A and C52S mutations lead to protein with substoichiometric heme (19% with respect to wild type);
184 Taken together, our results demonstrate that substoichiometric Hsp104 promotes compositional diversit
187 minimizes label concentration, allowing for substoichiometric in vivo eukaryotic protein labeling wh
189 r affinity, spanned the spectrum from strong substoichiometric inhibition (TKB) to stoichiometric inh
190 various drugs identified the need for strong substoichiometric inhibition of a carbonyl group on ring
191 nding reveals an unprecedented mechanism for substoichiometric inhibition of a gene-regulatory protei
192 nd (iii) highlight potential implications of substoichiometric inhibition of the viral protease in de
194 The mechanism of the stoichiometric and substoichiometric inhibitions of tubulin self-assembly b
196 t this single modification has a notable and substoichiometric inhibitory effect on alpha-synuclein a
197 chemical quench analysis has demonstrated a substoichiometric initial burst of ADP formation by free
200 p-BH(2)NMeH (1) and [MeNH-BH(2)](3) and with substoichiometric ItBu, [MeNH-BH(2)](3), and [MeNBH](3)
203 e procedure requires an ester, an amine, and substoichiometric KOtBu and was used to prepare a large
204 thod exists for controlled stoichiometric or substoichiometric labeling of proteins in live cells.
207 nsfer difference NMR, we demonstrate that at substoichiometric LC8 concentrations, the IDP domain pre
208 ne consumption, but only accumulated at low, substoichiometric levels ( approximately 10% yield) rela
209 tor of in vitro amyloid formation by IAPP at substoichiometric levels and protects cultured rat INS-1
212 d is increased when the reaction is run with substoichiometric levels of AdoMet or with the defective
213 0 mol of bound ATP per dimer equivalent, and substoichiometric levels of bound ADP (0.08-0.58 mol/dim
214 RK signaling both became more sustained when substoichiometric levels of erlotinib were added to redu
215 he formation of Sc237 prions is inhibited by substoichiometric levels of hamster unglycosylated PrPC
218 itination of Med3 offers a rationale for the substoichiometric levels of the tail module that are fou
219 ATP or ADP binding to FtsA* and occurred at substoichiometric levels relative to FtsZ, similar to ce
222 assays and microscopy, we show that MciZ, at substoichiometric levels to FtsZ, causes shortening of p
223 Second, streptavidin protein was added at substoichiometric levels to prepare a series of complexe
225 ence was identified in Phaseolus glabelus in substoichiometric levels, suggesting that the present-da
229 anhydrous Li2B12H12 begins to decompose to a substoichiometric Li2B12H12-x composition, which display
232 (3)H]-F2CDP have established that F2CDP is a substoichiometric mechanism based inhibitor (0.5 eq F2CD
233 t ring C contains the ability to induce both substoichiometric microtubule inhibition and GTPase acti
234 Roxbyite Cu(1.8)S nanoparticles react with a substoichiometric mixture of Zn(2+), Co(2+), In(3+), and
237 al, convergent route for the introduction of substoichiometric numbers of latent surface sites into d
246 Herein, we report the implementation of substoichiometric quantities of redox mediators to addre
247 stituted biaryl azides at 60 degrees C using substoichiometric quantities of Rh(2)(O(2)CC(3)F(7))(4)
249 subunits Rpd3 and RbAp48/p46 [8] as well as substoichiometric quantities of the deacetylase-associat
250 The purified protein was associated with substoichiometric quantities of tightly bound NADP+ and
251 iCl(2)/Xantphos catalyst in combination with substoichiometric quantities of zinc cyanide and polymet
252 n accelerate chemical reactions when used in substoichiometric quantities, a process known as organoc
253 s and the ability to use these organotins in substoichiometric quantities, the hazards and purificati
254 growth at the molecular level and in highly substoichiometric quantities, which can be exploited thr
256 e Fukuzumi acridinium photooxidant (1) and a substoichiometric quantity of a hydrogen-atom donor.
257 optimization, it has been determined that a substoichiometric quantity of piperidine (secondary amin
260 rmodynamically coupled and suggests that the substoichiometric ratio of CypA in the HIV-1 virion resu
264 ly inhibiting on-pathway fibril formation at substoichiometric ratios of Hsp104 to Abeta42 monomers.
265 the strong stabilizing effects on plus ends, substoichiometric ratios of Taxol bound to tubulin in mi
266 itivity to taxol, we measured the effects of substoichiometric ratios of taxol bound to tubulin in mi
267 illation of Alzheimer Abeta(1-40) peptide at substoichiometric ratios, albeit some more effectively t
270 uired for polymerization, but instead caused substoichiometric reductions in the amount of tubulin th
272 POT1-TPP1 increased processivity even when substoichiometric relative to the DNA, providing evidenc
273 ratio of 1:1, our data indicate that FADD is substoichiometric relative to TRAIL-Rs or DED-only prote
274 ow that Eha is nevertheless essential, and a substoichiometric requirement for H(2) suggests that its
277 and a pan-cancer set of fibrosis genes shows substoichiometric scaling with COL1A1 but predicts patie
280 lectrically biasing thin films of amorphous, substoichiometric silicon oxide drives surprisingly larg
282 e, either alone or with rubidium iodide, for substoichiometric, stoichiometric, and overstoichiometri
283 X was evaluated in abiotic experiments using substoichiometric, stoichiometric, and superstoichiometr
285 that differentiated B cells contain a novel substoichiometric TAF of 105 kDa not found associated wi
289 nd strand exchange requires amounts of Rad52 substoichiometric to Rad51 and involves a stable, equimo
290 lecular chaperone Hsp110, in a concentration substoichiometric to the mutant SOD1 protein, completely
291 factors, with a copy number per cell that is substoichiometric to the ribosome and similar to the abu
292 ) at concentrations of RecA protein that are substoichiometric to the ssDNA, arguing that LexA repres
295 stern signal strengths, Cox16p appears to be substoichiometric with Cox1p and Cox4p, which could indi
296 Interestingly, when E(C) concentrations were substoichiometric with respect to the N-terminal splicin
299 nantly expressed AztD purifies with slightly substoichiometric zinc from the periplasm of Escherichia
300 is unstable and only partially populated at substoichiometric Zn(II); a slight molar excess of zinc