ライフサイエンスコーパス: such

1 amus (MD) to frontal eye field (FEF) carries such a CD for saccadic eye movements.

2 e first oxaphosphetane (OPA) intermediate in such a domino reaction is examined within a topological-

3 Such a drug would raise the hope for a cure to many P2X7

4 ne to perform online sequence searches, yet, such a feature would be highly useful to investigators.

5 Discovery of such a feeding behavior in this ancient, terrestrial, an

6 However, past evidence suggesting such a gain adjustment rests on subjective measures of c

7 ms or better has recently been proposed, but such a goal would require equitable translation to count

8 Such a model could aid in the development of prebiotic,

9 The designed compounds containing such a salt bridge reached high oral bioavailability and

10 architectures, which allows for engineering such a selective multivalent metal ion binding site into

11 there is sufficient patient load to maintain such a service.

12 nization of this species provide the key for such a solution.

13 Such activity has typically been observed and interprete

14 line in the striatum plays a pivotal role in such adaptation, and its release has been causally assoc

15 versions of the mAb could be used to reduce such adverse reactions.

16 s, aldehydes and other carbonyl derivatives, such amides, ester and carboxylic acids, are presented i

17 Such an approach may be a general principle applicable t

18 In a simplistic sense, such an approach mimics the modes of activation and cont

19 However, the relevant characteristics of such an effort have been uncertain.

20 event in the LMA group and as not having had such an event in the face-mask group.

21 n advanced energy balance model to show that such an HZ would be considerably wider than originally p

22 There are limited data on how such anomalies affect deaths from injuries.

23 Cluster Of Clusters Analysis (COCA) is one such approach that has been widely applied in the contex

24 trix deposition in the diseased liver and as such are important in the progression of liver fibrosis.

25 incorporate physically incoherent attributes such as a construct of force-carrying beams that emanate

26 s must generally be packaged into a vehicle, such as a nanoparticle, that will allow them to be taken

27 dedicated structural features in the enzyme, such as a nucleotide hydrolysis site or multiple interme

28 range among various tested cancer cell lines such as A2780 (0.23 muM), PC3 (0.48 muM), and SKOV3 (0.5

29 t also by low molecular weight phosphodonors such as acetyl phosphate and carbamoyl phosphate.

30 hibited several electrophysiological changes such as action potential (AP) prolongation (~50%), reduc

31 weakening maladaptive memories in disorders such as addiction and post-traumatic stress disorder.

32 le double bond as the only functional group, such as alpha-pinene, beta-pinene and camphene, or two a

33 y of a wide range of serious human diseases, such as Alzheimer's disease and prion diseases.

34 explicit complexity control during training, such as an explicit regularization term.

35 virus (HIV) has driven novel interventions, such as antiretrovirals, for pre-exposure prophylaxis.

36 ombination with high-risk biological factors such as APOEepsilon4 and subcortical amyloid-beta may id

37 gnaling can trigger cardiovascular diseases, such as arteriovenous malformations.

38 xamined whether social environmental factors such as attachment style may moderate the relation betwe

39 s geared toward reducing surgical blood loss such as autologous transfusion techniques and agents to

40 basic NHC ligands and noncoordinating anions such as BAr(F)(4) catalyze the cis haloalkynylation of t

41 at can be used in other biological settings, such as being introduced into circuit designs for synthe

42 requires the presence of activator peptides, such as benzoyl-leucyl-leucine (Bz-LL), for function.

43 Moreover, chemical releasing methods, such as beta-elimination/Michael addition, are not speci

44 screte glycan motifs expressed on CD11b/CD18 such as biantennary galactose could represent novel targ

45 s improved, methods to assess Treg stability such as bisulfite Sanger sequencing to determine the met

46 ction and facilitate physiological function, such as blood pressure regulation.

47 iour is shaped by animal personality traits, such as boldness.

48 ased visitation from key pollinator species, such as bumble bees, at warmer sites.

49 are essential for cellular functions, others such as cadmium and arsenic are inherently cytotoxic.

50 successful experimental infections of pets, such as cats, ferrets and dogs, raises questions about t

51 nvolved in normal hair bundle morphogenesis, such as CDC42, RAC1, EPS8 and ESPNL.

52 on of publicly available administrative data such as census data.

53 corporation of adjunctive upfront treatments such as chemotherapy and novel anti-androgen agents has

54 be beneficial for the treatment of diseases such as chronic inflammation and ischemia-reperfusion in

55 he use of explosive reagents or toxic gases, such as CO, as the C1 synthon.

56 r switching nonlayered metallic ferromagnets such as CoFeB.

57 dle in the analysis of complex data in areas such as computational biology, ecology and econometrics.

58 ) by darapladib is dependent on many factors such as concentrations of detergents or lipoproteins, in

59 ex symptoms associated with parietal damage, such as constructional ataxia.

60 ally, we quantified cost changes by subtype, such as costs due to increased healthcare utilization an

61 ty to detect and track outbreaks of diseases such as COVID-19, investigate transmission chains and ex

62 Solitary intestinal lymphoid tissues such as cryptopatches (CPs) and isolated lymphoid follic

63 sed risk for adult onset metabolic diseases, such as diabetes and obesity.

64 at interventions to reduce AGE accumulation, such as dietary AGE restriction, may reduce cardiovascul

65 The utility of advanced MRI sequences such as diffusion-weighted imaging, dynamic contrast enh

66 The consequences of 53BP1 deficiency, such as diminished PARPi efficacy in BRCA1-deficient cel

67 Model organisms, such as Drosophila, can help to identify and characteriz

68 of L1000 data in the downstream applications such as drug repurposing, disease modeling and gene func

69 Anatomic imaging tools such as echocardiography and cardiac CT or CT angiograph

70 It is well-established that food proteins, such as egg, soya, cow's milk and wheat, are detectable

71 damage usually leads to detrimental effects such as embrittlement, accelerated creep, phase instabil

72 that non-haemodynamic tubulo-toxic factors, such as endotoxins and bile acids, might mediate parench

73 ate, most studies have focused on activators such as enhancers, but regions that repress gene express

74 rule out infection among high-risk persons, such as exposed inpatients and health care workers.

75 o-occurring redox steps in enzymatic systems such as ferritin.

76 adopted, combining non-invasive techniques, such as fiber optic reflectance spectroscopy (FORS), Ram

77 tional repressor of flowering-related genes, such as FLOWERING LOCUS T (FT), FLOWERING LOCUS C (FLC),

78 adian clocks to regulate critical behaviors, such as foraging orientation and navigation, time-memory

79 In complex tasks such as foraging, the internal state is dynamic(5-8).

80 ethods to broadly available clinical samples such as formalin-fixed and paraffin-embedded (FFPE) tiss

81 toms, additional model species are emerging, such as Fragilariopsis cylindrus and Pseudo-nitzschia mu

82 Peptides such as gastrin-releasing peptide receptors targeting ra

83 s can be applied to specific research fields such as genome stability and developmental biology and t

84 rtion, can differ from each other in aspects such as geographical distribution, intensity of transmis

85 mpete with high-performance synthetic fibers such as glass fibers and carbon fibers as well as to pro

86 Although hormones such as glucocorticoids have been broadly accepted in re

87 ules with spatially variant building blocks, such as gradient metasurfaces, are drawing substantial a

88 ivity can lead to diseases of iron overload, such as haemochromatosis, or iron limitation anaemias(2)

89 Compared to other loop callers, such as HiCCUPS and SIP, MUSTACHE recovers a higher numb

90 specificity for different effector proteins, such as HopZ1a.

91 , the cellular levels of oligomeric proteins such as Hsp20 are maintained post-translationally throug

92 rophobic layer and pyrolysed organic matter, such as hydrophobic surface binding proteins, laccases (

93 R1 by a selective small molecule antagonist, such as ICT12035, can provide a new avenue for the treat

94 case of the inner membrane 23 is compromised such as in temperature-sensitive mutants of Tim17.

95 ely by infinite-dimensional quantum systems (such as infinite-level systems arising from quantum harm

96 apo(a)'s potential pathological properties, such as inhibition of plasmin generation, have been attr

97 It is known that growth factors such as insulin, IGF-1 and HGF support beta cell growth

98 tokines that stimulate T cell proliferation, such as interleukin (IL)-15, have been explored as a mea

99 poxia is associated with pregnancy disorders such as intrauterine growth restriction and preeclampsia

100 While some metals such as iron and copper are essential for cellular funct

101 ry role to phylogenetic tree-based analysis, such as is done in the Nextstrain project.

102 nction, and fundamental changes in behaviors such as learning, memory, and social interactions.

103 The variation in several metabolite pools such as malate, fumarate or citrate, and flux calculatio

104 ng factor to impairment in cognitive domains such as memory and perceptual reasoning, and act as inte

105 cobalt(0) precatalysts, and protic solvents such as methanol and isopropanol were identified as opti

106 be applied to investigate other RNA systems, such as multiway junctions or pseudoknots in mixed metal

107 We review techniques such as mutagenesis, chemical modifications, and optogen

108 increasing the expression of proto-oncogenes such as MYC and cyclins.

109 lcogenophosphates exhibit unique properties, such as negative electrostriction and multi-well ferriel

110 We discuss approaches such as neurostimulation and pharmacological neuromodula

111 ence of complications of metabolic syndrome, such as non-alcoholic fatty liver disease.

112 capillary networks, we accounted for factors such as non-uniform vascular density and permeability th

113 r high-value products from simple feedstocks such as olefins.

114 ce of different forms of extracellular PDL1, such as on exosomes or as a freely soluble protein, and

115 Using in vivo imaging, such as optical coherence tomography, scanning laser oph

116 the human femoral head affected by a disease such as osteoarthritis.

117 cytosolic shuttling, regulating HuR targets such as p53, p27, Caspase-9, and BCL2.

118 uence of particle mixing state on properties such as particle deposition in the lung, the large spati

119 mmune responses using checkpoint inhibitors, such as PD-1 or PD-L1 inhibitors.

120 ghlight combinations of NNs with other ideas such as permutationally invariant polynomials or sums of

121 the need for developing other technologies, such as phage therapy.

122 d developmental biology and to test concepts such as phase separation of chromatin.

123 crease in the total levels of complex lipids such as phosphatidylethanolamines (PE), lactosylceramide

124 ical properties of complex-oxide thin films, such as piezoelectricity and magnetostriction, are sever

125 e material properties of bioinspired systems such as pollen paper opens the door to a wide range of s

126 rene sulfonate, and +10 to +15% for polymers such as poly(2-(3,3'-bis(2-(2-(2-methoxyethoxy)ethoxy)et

127 Some compounds present in chicory, such as polyphenols, inulin, oligofructose and sesquiter

128 IR) highlighting a series of critical steps, such as preprocessing, data selection, feature extractio

129 for monogenic disorders of the blood system such as primary immunodeficiencies and beta-thalassaemia

130 ectral images and the MSI data specifically, such as principal component analysis, independent compon

131 Our findings suggest that exogenous factors, such as procedural differences between red and white win

132 for the oxidative dehydrogenation of alkanes such as propane.

133 ths of macromolecular conformational changes such as protein folding are predicted to be heterogeneou

134 complexity of molecular target interactions, such as protein-protein interaction (PPI), remains to be

135 Given that risk for fear-related disorders, such as PTSD, is biased toward females, we examined whet

136 well as use of appropriate local treatments such as radiation therapy, orthopaedic surgery and speci

137 tion of the canisters, plug, and SNF itself, such as radiolysis and attack by constituents of hydroth

138 s the replication of intravacuolar pathogens such as Salmonella Here, we show that this mechanism req

139 External stimulations such as seafloor hydrocarbon seeps have been demonstrate

140 d beyond fostering person-level dispositions such as self-esteem.

141 f other analytical figures of merit (AFOMs), such as sensitivity, analytical sensitivity, and limits

142 with reactive components of mineral surfaces such as silicate radicals and ferrous iron.

143 quantifying a broad range of single analytes such as small molecules, proteins, nanoparticles, exosom

144 proaches aiming to destabilize MYCN protein, such as small-molecule inhibitors of Aurora A and mTOR,

145 and deployment of novel technical solutions such as smartphone applications, telemedicine, and mobil

146 y be useful in promoting healthier behaviors such as smoking cessation or in aiding persons with a fa

147 Risk-averse behaviours, such as standing on 'safe' blocks and testing blocks pri

148 However, as conditions such as starvation require the organism to be awake and

149 studied using different spectroscopic tools such as steady-state & time-resolved fluorescence spectr

150 luting highly specialized microenvironments, such as stem cell (SC) niches.

151 Treatment with aminoglycosides such as streptomycin or gentamicin is effective when ini

152 es are emerging tools in a variety of fields such as structural biology, cell imaging, and drug disco

153 tegies include the use of novel electrolytes such as superconcentrated electrolytes, localized high-c

154 and is associated with electronic phenomena such as superconductivity, colossal magnetoresistances (

155 ts, activity-dependent synaptic adaptations, such as synaptic scaling, stabilize neuronal activity in

156 Other quality parameters such as texture, drip loss and colour were evaluated wit

157 ties by the sequencing of housekeeping genes such as that encoding the small subunit ribosomal RNA ha

158 a with or without allele dosage information, such as that from microarray or sequencing experiments.

159 Cancer stem cells (CSCs) have features such as the ability to self-renew, differentiate into de

160 ld be applied to large-scale cancer studies, such as The Cancer Genome Atlas (TCGA), with both RNA-Se

161 is crucial for many biological applications such as the design of guide RNA for CRISPR experiments.

162 a membrane receptor tyrosine kinases (RTKs), such as the epidermal growth factor receptor (EGFR), loc

163 eting tumour-specific driver gene mutations, such as the four-nucleotide duplication in the oncogene

164 a plethora of composite topological defects such as the fourfold junctions, the bimeron and the targ

165 on and dynamics of membrane-bound organelles such as the Golgi apparatus, remain elusive.

166 ression between distantly related cell types such as the immune-related genes that were similarly exp

167 oding frequency focus on endpoint scenarios, such as the increase in flooding by 2050 or 2100.

168 Commonly used survival analysis techniques, such as the Kaplan-Meier method, often are not appropria

169 rs of memory processes, sex steroid hormones such as the potent oestrogen 17beta-oestradiol have been

170 me of the calculated structural observables, such as the relative accessible surface area and the int

171 ur ability to link infinite building blocks, such as the ribbons of COF-76, into higher dimensionalit

172 ces many key features of ecological systems, such as the role of generalists during assembly, realist

173 concerning understudied migration pathways, such as the Sicilian route.

174 and explore large-scale population dynamics, such as the spread of antibiotic resistance.

175 e trade-off among chemical design parameters such as the surface density of enzymes, various reaction

176 pointed to the existence of New World crops, such as the sweet potato and bottle gourd, in the Polyne

177 ircuits can incorporate subcortical regions, such as the thalamus and brainstem nuclei, which mediate

178 The notable features such as the use of air that is considered as a benign ox

179 essments can be done using existing methods, such as those established for development of national su

180 the APR, including surveillance for species such as those identified during this horizon scanning ex

181 ineer crops for entirely novel environments, such as those in space travel.

182 omatic paroxysmal AF in at-risk populations (such as those with cryptogenic stroke), the refinement o

183 available treatments are hampered by issues such as toxicity, variable efficacy, and unsuitable dosi

184 thereby focusing the pathway on select sites such as transcriptionally active genes.

185 cting clinically relevant tumour behaviours, such as treatment response and emergence of drug resista

186 Although conventional genomic markers (such as tumor mutation burden and neoantigen load) and t

187 zed by common, clinically variable symptoms, such as typical facial dysmorphisms, short stature, deve

188 However, other properties such as ultimate toughness, tensile strength, poroviscoe

189 velocities are useful for retrieving signals such as uplift along elevated viaducts of Metro lines 4

190 We conclude by proposing strategies-such as using more diverse training datasets that includ

191 f RelA and c-Rel signaling dynamic features, such as variations in duration or time-integrated activi

192 ity and infection rates, landscape features, such as vegetation cover and water body availability, pl

193 and it is unclear whether well-studied taxa, such as vertebrates, reflect changes in wider biodiversi

194 otein, regulates various cellular functions, such as vesicle trafficking, activity of the Rab3 and Ra

195 ve sometimes produced contradictory results, such as whether CCL2 or IL12 define effective monocyte r

196 ithin ter, and interacts with other proteins such as ZapB.

197 Receptor-like cytoplasmic kinases (RLCKs) such as ZED1, interact with ZAR1 and provide specificity

198 the mirGFF3 format directly into their code, such as, miRge2.0, IsoMIRmap and OptimiR.

199 However, no such asymmetry was observed in assays performed in the p

200 Such behavior can be isolated in the reinforcer devaluat

201 However, such behavior is possible without storing images of shap

202 Hybrid integration of such biosensors with extremely well-established silicon-

203 arious S(h) over its range of variation, but such calibrations are precluded because of lack of exper

204 ward redox reactions due to the fact that in such cases two electrons from the coordinated amide are

205 In such cases, we face a natural trade-off between breadth-

206 Such categories can facilitate the transmission of cultu

207 er, conventional synthesis routes to produce such ceramic NWs have prohibitively high cost.

208 Such changes can lead to profound changes in behavior, b

209 movements of the eye or optic nerve, and if such changes could be linked to SANS.

210 Under such circumstances, the aggregation commences after appr

211 ling the drivers of natural selection within such communities is extremely challenging, and it is thu

212 mmetric two-sided loop extrusion can achieve such compaction, but recent single-molecule studies (Gol

213 vior, and that it should be essential to any such comparison.

214 Such coupling between all equilibrium-governing paramete

215 sed as diseases that need to be addressed in such crises.

216 S phenotype.Objectives: To determine whether such Crs-based phenotypes existed among patients with AR

217 napses due to the difficulties in collecting such data.

218 wever, the kinetic pathways, following which such development occurs, have been largely unexplored du

219 As such, discovering signaling pathways that modulate album

220 l intake influences plasma lipid levels, and such effects may be moderated by genetic variants.

221 of nematode effector proteins in triggering such epigenome changes is discussed.

222 We identified three such epitopes derived from highly conserved regions with

223 e developers and users to reduce the risk of such errors.

224 downstream of PAR4 activation that leads to such events.

225 However, such experiments can be time-consuming and costly, which

226 change energy density, skyrmions may exhibit such extreme deformation that spontaneous merging with n

227 erimental methods to systematically identify such extreme interactions.

228 More generally, such findings raise concerns regarding society's mental

229 Such fitness trade-offs include reduced virulence, resen

230 Although such flow patterns can be, in principle, described by th

231 Such fragmentation has been reported to impact a small f

232 However, such frameworks perform far less favorably when evaluate

233 g this theory, many striatal neurons exhibit such graded changes without bursting near specific actio

234 imental and modeling approaches to elucidate such impacts in flow-electrode capacitive deionization (

235 oaches for using in vitro data to anticipate such in vivo effects exist.

236 , affecting probably no more than 1 in 1,000 such infected individuals.

237 high levels of readiness and acceptance for such interventions.

238 r, the role and fate of the oxide ligands in such intriguing additional capacity remain unclear.

239 Typically, such investigations have taken a 'black box' approach in

240 Such ion-by-ion diffusion and attachment may occur from

241 lls from almost the entire blood volume, but such large numbers and concentrations of cells are incom

242 alities can be coupled by stacking layers of such materials to create heterostructures and can be fur

243 irritability compared with those not taking such medications.

244 Although salts of such metals as vanadium, niobium, cerium, and manganese

245 The application of such methods to broadly available clinical samples such

246 trol and therapeutic medical applications of such micro/nanorobots are introduced.

247 To address this problem, we generalized such models by adopting a nonparametric approach in whic

248 A major problem with such mouse models is that bnAb expression often hinders

249 indicated that Grubbs-type catalysts possess such multitask activity, catalyzing the transvinylation

250 Such near-freezing temperatures have not previously been

251 It is not known whether such neuroadaptations are affected by number of days of

252 s, and a reduced length of stay was seen for such patients.

253 use of HES for volume replacement therapy in such patients.

254 ult to isolate and then single-cell sequence such populations because of compounding losses.

255 Such potentials were generally thought to be an essentia

256 idation, experimental tools for the study of such processes, as well as the recent discoveries by lea

257 ts who are HLA-A*01:01pos could benefit from such products, since no T cells recognizing any EBV-deri

258 Such progress will impact the academic sector as new for

259 Why is there such prominent variation in sexual receptivity length am

260 However, the role of such proteins in regulating cellular processes in vivo a

261 the generic spatial transport properties of such proteins, we investigate here whether their ability

262 However, such reactivity has proven difficult to reproduce in sol

263 As such, readmission after AMI has been a target of financi

264 The choice of such representations impacts the performance and outcome

265 et (PDNET), a framework that consists of one such representative dataset along with the scripts for t

266 One such rhythm is a diurnal shift in symbiont metabolism tr

267 a mapping from the linear folding motions of such sheets to force-bearing modes in conjunction with t

268 The genetic entities in such simulations should not be generic but should be rep

269 -Meier method, often are not appropriate for such situations.

270 Such soliton microcombs(10) have been applied to spectro

271 Such specialized secretion systems allow a variety of ba

272 tivity profiles and so cannot be targeted by such strategies.

273 ostyle, which evolved nearly 200 MYA, is one such structure.

274 ssembly intermediates, and indeed we observe such structures by negative stain EM of in vitro assembl

275 well-understood electronic transport within such structures will potentially lead to accessible devi

276 as biological variable and the execution of such studies, particularly in genomic studies of human c

277 As we continue to build such supportive environments, we can see that they will

278 talysts and electrocatalytic applications of such supramolecular assemblies.

279 wever, the tunable functional performance of such systems is still largely hampered by their poor ele

280 sed deep learning framework is effective for such task.

281 Based on such temperature control strategy, NGD sensitivity and t

282 bility changes from the site of stimulation, such that after active treatment, the dlPFC appeared bet

283 n applied post hoc to the resulting ensemble such that averaged peptide-deuteration levels, as predic

284 of death was inversely proportional to age, such that frailty had a stronger adverse impact on young

285 individual differences in cognitive ability, such that greater cognitive ability is increasingly asso

286 cably coupled with effective spatial scales, such that higher growth rates cause more localized compe

287 However, when the task was such that ingroup and self associations competed, only t

288 of UBA I seed crystals modified this pathway such that only UBA I was observed throughout, while tran

289 pears to be dependent on pollinator identity such that reduced reproduction may be attributable to de

290 rences in the change of TIB devoted to sleep such that students with shorter TIB at baseline before t

291 a beta-propeller protein that binds to SMCR8 such that the whole structure resembles an eye slip hook

292 osomal genes independently influence mitosis such that their phenotypic consequences can be combined

293 with improvement of these energetic changes such that there was no significant difference in compari

294 As such, the relevance of OXPHOS status and role of CI muta

295 We show that such tracking can be achieved by canonical network archi

296 tabolic health changes over time and whether such transition affects risks of subtypes of CVD in Chin

297 g resistance, is in principle susceptible to such traps.

298 Such unprecedented water-stability has been applied to p

299 Given such variation among species, broad generalizations abou

300 As such, while all treatments depleted a significant propor