ライフサイエンスコーパス: such as

1 to track the flux of other labeled tracers (such as (15)N-tracers) in any metabolite detectable by L

2 incorporate physically incoherent attributes such as a construct of force-carrying beams that emanate

3 s must generally be packaged into a vehicle, such as a nanoparticle, that will allow them to be taken

4 dedicated structural features in the enzyme, such as a nucleotide hydrolysis site or multiple interme

5 range among various tested cancer cell lines such as A2780 (0.23 muM), PC3 (0.48 muM), and SKOV3 (0.5

6 t also by low molecular weight phosphodonors such as acetyl phosphate and carbamoyl phosphate.

7 hibited several electrophysiological changes such as action potential (AP) prolongation (~50%), reduc

8 weakening maladaptive memories in disorders such as addiction and post-traumatic stress disorder.

9 le double bond as the only functional group, such as alpha-pinene, beta-pinene and camphene, or two a

10 y of a wide range of serious human diseases, such as Alzheimer's disease and prion diseases.

11 ease in signal intensity for polar molecules such as amino acids, which has important implications fo

12 explicit complexity control during training, such as an explicit regularization term.

13 Research on eukaryotes such as animals, plants, oomycetes and fungi has shown t

14 nally coupled with other statistical methods such as ANOVA, is demonstrated on altogether twelve case

15 virus (HIV) has driven novel interventions, such as antiretrovirals, for pre-exposure prophylaxis.

16 ombination with high-risk biological factors such as APOEepsilon4 and subcortical amyloid-beta may id

17 However, some species, such as Arctic-breeding geese, have thrived during this

18 of thrombotic or pro-inflammatory conditions such as arterial thrombosis.

19 gnaling can trigger cardiovascular diseases, such as arteriovenous malformations.

20 quences of these changes on distinct targets such as astrocytes, which exhibit norepinephrine-depende

21 xamined whether social environmental factors such as attachment style may moderate the relation betwe

22 or the management of neurological disorders, such as autism and intellectual disability, that are cha

23 ogical disorders and neurogenetic syndromes, such as autism spectrum disorder (ASD) and Dravet, Fragi

24 s geared toward reducing surgical blood loss such as autologous transfusion techniques and agents to

25 tors of these responses and related pathways such as autophagy and apoptosis.

26 basic NHC ligands and noncoordinating anions such as BAr(F)(4) catalyze the cis haloalkynylation of t

27 ve a scaling law for linear elastic matrices such as basement membrane extract hydrogels (Matrigel) t

28 at can be used in other biological settings, such as being introduced into circuit designs for synthe

29 iometric quantities of undesirable oxidants, such as benzoquinone and silver(I) salts.

30 requires the presence of activator peptides, such as benzoyl-leucyl-leucine (Bz-LL), for function.

31 Moreover, chemical releasing methods, such as beta-elimination/Michael addition, are not speci

32 screte glycan motifs expressed on CD11b/CD18 such as biantennary galactose could represent novel targ

33 s improved, methods to assess Treg stability such as bisulfite Sanger sequencing to determine the met

34 ction and facilitate physiological function, such as blood pressure regulation.

35 iour is shaped by animal personality traits, such as boldness.

36 cale of design interventions and placemaking such as building orientation and access, street furnishi

37 ased visitation from key pollinator species, such as bumble bees, at warmer sites.

38 some of the negative consequences of nursing such as burnout and compassion fatigue.

39 ite the abundant presence of HDAC inhibitors such as butyrate in the intestine, we found that HDAC3 a

40 onversion of chitin into complex glycosides, such as C5-modified sialosides, through the use of highl

41 are essential for cellular functions, others such as cadmium and arsenic are inherently cytotoxic.

42 n of a small fraction of hydrated materials, such as carbonaceous chondrite meteorites, which origina

43 successful experimental infections of pets, such as cats, ferrets and dogs, raises questions about t

44 nvolved in normal hair bundle morphogenesis, such as CDC42, RAC1, EPS8 and ESPNL.

45 on of publicly available administrative data such as census data.

46 corporation of adjunctive upfront treatments such as chemotherapy and novel anti-androgen agents has

47 ly cause mild symptoms; however, individuals such as children, those with underlying conditions, and

48 e consuming and often employs toxic solvents such as chloroform.

49 modulators, including endogenous compounds, such as cholesterol and neurosteroid pregnenolone sulfat

50 be beneficial for the treatment of diseases such as chronic inflammation and ischemia-reperfusion in

51 he use of explosive reagents or toxic gases, such as CO, as the C1 synthon.

52 r switching nonlayered metallic ferromagnets such as CoFeB.

53 greater importance than biotic interactions such as competition.

54 rian and bicycle networks and infrastructure such as Complete Streets policies and Safe Routes to Sch

55 e log-likelihood of complex models in fields such as computational biology and neuroscience is often

56 dle in the analysis of complex data in areas such as computational biology, ecology and econometrics.

57 ) by darapladib is dependent on many factors such as concentrations of detergents or lipoproteins, in

58 ly been tested using simple force protocols, such as constant or ramped forces.

59 ex symptoms associated with parietal damage, such as constructional ataxia.

60 the emergence of human-specific capacities, such as constructive episodic simulation.

61 haracterized by local morphological features such as cortical thickness, myelin content, and gene exp

62 ally, we quantified cost changes by subtype, such as costs due to increased healthcare utilization an

63 revalence of HBV infection of 2% or greater, such as countries in Africa and Asia, the Pacific Island

64 strands difficult, or chemical modification, such as covalent crosslinking of DNA strands.

65 ty to detect and track outbreaks of diseases such as COVID-19, investigate transmission chains and ex

66 ure, it remains unclear how defensive traits such as crypsis, activity levels and speed influence rea

67 Solitary intestinal lymphoid tissues such as cryptopatches (CPs) and isolated lymphoid follic

68 In recent years, bioisosteres such as cubane and bicyclo[1.1.1]pentane (BCP) have been

69 This included genes such as DCC, which encodes the netrin-1 receptor and has

70 Aedes-borne diseases, such as dengue and chikungunya, are responsible for more

71 Typically, nonspecialists such as dentists screen for oral cancer risk, and then t

72 sed risk for adult onset metabolic diseases, such as diabetes and obesity.

73 at interventions to reduce AGE accumulation, such as dietary AGE restriction, may reduce cardiovascul

74 The utility of advanced MRI sequences such as diffusion-weighted imaging, dynamic contrast enh

75 The consequences of 53BP1 deficiency, such as diminished PARPi efficacy in BRCA1-deficient cel

76 ability to perform basic cellular functions such as division and motility.

77 Model organisms, such as Drosophila, can help to identify and characteriz

78 Each year, abiotic stress conditions such as drought, heat, salinity, cold and particularly t

79 ymers widely used in pharmaceutical industry such as drug coatings due to their low cost, processabil

80 of L1000 data in the downstream applications such as drug repurposing, disease modeling and gene func

81 zed for specialized physiological functions, such as during axon myelination.

82 Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans hav

83 Anatomic imaging tools such as echocardiography and cardiac CT or CT angiograph

84 It is well-established that food proteins, such as egg, soya, cow's milk and wheat, are detectable

85 nicians to explore other therapeutic options such as electroconvulsive therapy, transcranial magnetic

86 Advances in imaging methods such as electron microscopy, tomography, and other modal

87 damage usually leads to detrimental effects such as embrittlement, accelerated creep, phase instabil

88 that non-haemodynamic tubulo-toxic factors, such as endotoxins and bile acids, might mediate parench

89 ate, most studies have focused on activators such as enhancers, but regions that repress gene express

90 ty in psychiatric and neurological diseases, such as epilepsy.

91 ols by either method, whereas other viruses, such as Epstein-Barr virus (EBV) and cytomegalovirus (CM

92 nal, pharmacologic, and other interventions, such as exercise, for cancer cachexia.

93 rule out infection among high-risk persons, such as exposed inpatients and health care workers.

94 identify dynamically important cell states, such as fate decision states in differentiation.

95 onitored, and intermediate [2Fe-2S] species, such as (FDX2:GLRX5:[2Fe-2S]:GSH) and (FDX2:BOLA3:GLRX5:

96 s associated with certain behavioral states, such as fear (Monavarfeshani et al., 2017; Salay et al.,

97 g patients' individual symptom trajectories, such as feeling depressed, social, and calm and hearing

98 o-occurring redox steps in enzymatic systems such as ferritin.

99 adopted, combining non-invasive techniques, such as fiber optic reflectance spectroscopy (FORS), Ram

100 tional repressor of flowering-related genes, such as FLOWERING LOCUS T (FT), FLOWERING LOCUS C (FLC),

101 ng way of protecting highly unsaturated oils such as FO against oxidation.

102 ion and controls dynamic cellular processes, such as focal adhesion formation and turnover and cell d

103 ls provide numerous ecosystem services (ESs) such as food production and water purification.

104 adian clocks to regulate critical behaviors, such as foraging orientation and navigation, time-memory

105 In complex tasks such as foraging, the internal state is dynamic(5-8).

106 ethods to broadly available clinical samples such as formalin-fixed and paraffin-embedded (FFPE) tiss

107 toms, additional model species are emerging, such as Fragilariopsis cylindrus and Pseudo-nitzschia mu

108 Peptides such as gastrin-releasing peptide receptors targeting ra

109 s can be applied to specific research fields such as genome stability and developmental biology and t

110 rtion, can differ from each other in aspects such as geographical distribution, intensity of transmis

111 mpete with high-performance synthetic fibers such as glass fibers and carbon fibers as well as to pro

112 Although hormones such as glucocorticoids have been broadly accepted in re

113 ules with spatially variant building blocks, such as gradient metasurfaces, are drawing substantial a

114 actinobacterial species, or model conditions such as growth in vitro, in macrophages and in the mouse

115 ivity can lead to diseases of iron overload, such as haemochromatosis, or iron limitation anaemias(2)

116 to explaining other macroscopic properties, such as hardness.

117 sensors in various physiological processes, such as hearing and touch.

118 fibres in vitro in the absence of additives such as heparin.

119 Compared to other loop callers, such as HiCCUPS and SIP, MUSTACHE recovers a higher numb

120 igrants from plastics in challenging samples such as honey.

121 specificity for different effector proteins, such as HopZ1a.

122 , the cellular levels of oligomeric proteins such as Hsp20 are maintained post-translationally throug

123 can be found extracellularly in body fluids such as human blood plasma and cerebrospinal fluid (CSF)

124 rophobic layer and pyrolysed organic matter, such as hydrophobic surface binding proteins, laccases (

125 tand the microvasculature's role in diseases such as hypertrophic cardiomyopathy where misalignment o

126 R1 by a selective small molecule antagonist, such as ICT12035, can provide a new avenue for the treat

127 n of pro-inflammatory tumorigenic cytokines, such as IL-17A and IL-6, and increased STAT3 tyrosine ph

128 case of the inner membrane 23 is compromised such as in temperature-sensitive mutants of Tim17.

129 CL from other causes of seroma accumulation, such as infection or trauma.

130 ely by infinite-dimensional quantum systems (such as infinite-level systems arising from quantum harm

131 itical mediators of physiological processes, such as inflammation, fever, allergy, and pain, their ro

132 eration of additional experimental evidence (such as information on biotransformation pathways) incre

133 apo(a)'s potential pathological properties, such as inhibition of plasmin generation, have been attr

134 It is known that growth factors such as insulin, IGF-1 and HGF support beta cell growth

135 tokines that stimulate T cell proliferation, such as interleukin (IL)-15, have been explored as a mea

136 poxia is associated with pregnancy disorders such as intrauterine growth restriction and preeclampsia

137 While some metals such as iron and copper are essential for cellular funct

138 ry role to phylogenetic tree-based analysis, such as is done in the Nextstrain project.

139 nction, and fundamental changes in behaviors such as learning, memory, and social interactions.

140 may be used for other value-added processes such as liquid fuel production.

141 fective strategies rely on unusual materials such as liquid metals, nanowires, and woven textiles or

142 networks of higher complexity are assembled, such as logic AND gates and IMPLY gates.

143 Chronic pain, encompassing conditions, such as low back pain, arthritis, persistent post-surgic

144 The variation in several metabolite pools such as malate, fumarate or citrate, and flux calculatio

145 nt high-dimensional single-cell technologies such as mass cytometry are enabling time series experime

146 that maternal effects on early life survival such as maternal age may act through their influence on

147 n summarizes selected applications in areas, such as medicine, biology, oceanography, bioprocess moni

148 ng factor to impairment in cognitive domains such as memory and perceptual reasoning, and act as inte

149 ively scale-up opioid agonist therapy (OAT), such as methadone or buprenorphine maintenance therapy,

150 cobalt(0) precatalysts, and protic solvents such as methanol and isopropanol were identified as opti

151 Stimulants such as methylphenidate are increasingly used for cognit

152 y LC-MS/MS and in various biological models (such as mice).

153 the mirGFF3 format directly into their code, such as, miRge2.0, IsoMIRmap and OptimiR.

154 that cellular stress created by neurotoxins such as MPTP and 6-hydroxydopamine can upregulate VGluT2

155 clinically beneficial in autoimmune diseases such as multiple sclerosis.

156 be applied to investigate other RNA systems, such as multiway junctions or pseudoknots in mixed metal

157 We review techniques such as mutagenesis, chemical modifications, and optogen

158 increasing the expression of proto-oncogenes such as MYC and cyclins.

159 lcogenophosphates exhibit unique properties, such as negative electrostriction and multi-well ferriel

160 tributes to in utero developmental processes such as neural proliferation, migration, and differentia

161 hermal history hold promise for applications such as neuromorphic computing, atomic clocks, thermomet

162 We discuss approaches such as neurostimulation and pharmacological neuromodula

163 supplies of biologically limiting nutrients, such as nitrogen (N) and phosphorus (P), which can reduc

164 ence of complications of metabolic syndrome, such as non-alcoholic fatty liver disease.

165 Unfortunately, most public databases, such as non-redundant (NR), rely on user input and do no

166 capillary networks, we accounted for factors such as non-uniform vascular density and permeability th

167 ting both physiological intestinal functions such as nutrient absorption and motility(2,3), and brain

168 r high-value products from simple feedstocks such as olefins.

169 ce of different forms of extracellular PDL1, such as on exosomes or as a freely soluble protein, and

170 Using in vivo imaging, such as optical coherence tomography, scanning laser oph

171 f nuclear gene expression, return to levels, such as, or even higher than, those in flu Without SAFE1

172 self-organization in emerging model systems such as organoids.

173 the human femoral head affected by a disease such as osteoarthritis.

174 cytosolic shuttling, regulating HuR targets such as p53, p27, Caspase-9, and BCL2.

175 uence of particle mixing state on properties such as particle deposition in the lung, the large spati

176 mmune responses using checkpoint inhibitors, such as PD-1 or PD-L1 inhibitors.

177 ghlight combinations of NNs with other ideas such as permutationally invariant polynomials or sums of

178 the need for developing other technologies, such as phage therapy.

179 d developmental biology and to test concepts such as phase separation of chromatin.

180 crease in the total levels of complex lipids such as phosphatidylethanolamines (PE), lactosylceramide

181 f incomplete material or that another factor such as phylogeny might impact size estimates and compar

182 ical properties of complex-oxide thin films, such as piezoelectricity and magnetostriction, are sever

183 ressor posing potential hazards to organisms such as planktonic crustaceans.

184 e material properties of bioinspired systems such as pollen paper opens the door to a wide range of s

185 rene sulfonate, and +10 to +15% for polymers such as poly(2-(3,3'-bis(2-(2-(2-methoxyethoxy)ethoxy)et

186 ion state of a film of a conducting polymer, such as poly(3-octylthiophene) [POT], that is in back-si

187 ctive hydrogels using bi-functional monomers such as poly(pyrrole-co-3-pyrrolylbutyrate-conj-aminoeth

188 unusual properties of bnAb variable regions, such as poly-reactivity and long antigen-binding loops,

189 Some compounds present in chicory, such as polyphenols, inulin, oligofructose and sesquiter

190 rane protein studies often require additives such as precipitants (e.g., polyethylene glycol (PEG)),

191 ectively examined sex-specific risk factors, such as premature menopause and early menarche, with ris

192 IR) highlighting a series of critical steps, such as preprocessing, data selection, feature extractio

193 for monogenic disorders of the blood system such as primary immunodeficiencies and beta-thalassaemia

194 ectral images and the MSI data specifically, such as principal component analysis, independent compon

195 Our findings suggest that exogenous factors, such as procedural differences between red and white win

196 on, with emphasis on modifiable risk factors such as promoting physical activity.

197 for the oxidative dehydrogenation of alkanes such as propane.

198 ths of macromolecular conformational changes such as protein folding are predicted to be heterogeneou

199 protein synthesis (MPS) to anabolic stimuli such as protein ingestion (and the ensuing hyperaminoaci

200 complexity of molecular target interactions, such as protein-protein interaction (PPI), remains to be

201 es is vital to many biological applications, such as protein-protein interaction prediction and liter

202 Given that risk for fear-related disorders, such as PTSD, is biased toward females, we examined whet

203 unds that pups cannot synthesise themselves, such as pyridoxine/vitamin B6, taurine, some essential a

204 well as use of appropriate local treatments such as radiation therapy, orthopaedic surgery and speci

205 tion of the canisters, plug, and SNF itself, such as radiolysis and attack by constituents of hydroth

206 ochasticity and deterministic perturbations, such as recruitment, fecundity of experienced individual

207 mptoms of Best vitelliform macular dystrophy such as reduced electro-oculogram, lipofuscin accumulati

208 eyes of 54 patients with different RD types, such as rhegmatogenous RD (RRD) without proliferative vi

209 re usually assessed with invasive procedures such as right heart catheterization and histopathology.

210 s the replication of intravacuolar pathogens such as Salmonella Here, we show that this mechanism req

211 f neurodevelopmental psychiatric conditions, such as schizophrenia and autism, in the offspring.

212 External stimulations such as seafloor hydrocarbon seeps have been demonstrate

213 d beyond fostering person-level dispositions such as self-esteem.

214 f other analytical figures of merit (AFOMs), such as sensitivity, analytical sensitivity, and limits

215 vity of TIM-1 while host restriction factors such as SERINC5 can enhance it.

216 g BLI platforms for urgent COVID-19 studies, such as serosurveillance and the evaluation of vaccine c

217 or on optimally configured 2D/3D structures such as serpentines and helical coils of conventional ma

218 with reactive components of mineral surfaces such as silicate radicals and ferrous iron.

219 quantifying a broad range of single analytes such as small molecules, proteins, nanoparticles, exosom

220 traits conferring more tolerance to drought such as small sclerophyllous leaves and lower percent lo

221 proaches aiming to destabilize MYCN protein, such as small-molecule inhibitors of Aurora A and mTOR,

222 and deployment of novel technical solutions such as smartphone applications, telemedicine, and mobil

223 y be useful in promoting healthier behaviors such as smoking cessation or in aiding persons with a fa

224 effective measurements of emerging materials such as solar materials, electrocatalysts, and nanomater

225 polar latitudes via a wide range of routes, such as some persistent organic pollutants (POPs).

226 ed for decoding multidimensional information such as spatially diffuse patterns.

227 Risk-averse behaviours, such as standing on 'safe' blocks and testing blocks pri

228 However, as conditions such as starvation require the organism to be awake and

229 studied using different spectroscopic tools such as steady-state & time-resolved fluorescence spectr

230 luting highly specialized microenvironments, such as stem cell (SC) niches.

231 eful source of essential bioactive compounds such as steroids, flavonoids and phenylpropanoid glycosi

232 ld compared with nontarget lipase activities such as Streptomyces chromofuscus PLD or serum lipase.

233 Treatment with aminoglycosides such as streptomycin or gentamicin is effective when ini

234 es are emerging tools in a variety of fields such as structural biology, cell imaging, and drug disco

235 tegies include the use of novel electrolytes such as superconcentrated electrolytes, localized high-c

236 and is associated with electronic phenomena such as superconductivity, colossal magnetoresistances (

237 ts, activity-dependent synaptic adaptations, such as synaptic scaling, stabilize neuronal activity in

238 Other quality parameters such as texture, drip loss and colour were evaluated wit

239 ties by the sequencing of housekeeping genes such as that encoding the small subunit ribosomal RNA ha

240 a with or without allele dosage information, such as that from microarray or sequencing experiments.

241 hat associate with features of the filament, such as the 11 stripes of accessory proteins.

242 Cancer stem cells (CSCs) have features such as the ability to self-renew, differentiate into de

243 ent advancements in predictive pharmacology, such as the application of multitask and transfer learni

244 ld be applied to large-scale cancer studies, such as The Cancer Genome Atlas (TCGA), with both RNA-Se

245 is crucial for many biological applications such as the design of guide RNA for CRISPR experiments.

246 a membrane receptor tyrosine kinases (RTKs), such as the epidermal growth factor receptor (EGFR), loc

247 -based thermal desorption (F-TD) techniques, such as the filter inlet for gases and aerosols, are wid

248 eting tumour-specific driver gene mutations, such as the four-nucleotide duplication in the oncogene

249 a plethora of composite topological defects such as the fourfold junctions, the bimeron and the targ

250 on and dynamics of membrane-bound organelles such as the Golgi apparatus, remain elusive.

251 Additionally, viral factors such as the HIV-1 accessory protein Nef can antagonize t

252 ression between distantly related cell types such as the immune-related genes that were similarly exp

253 oding frequency focus on endpoint scenarios, such as the increase in flooding by 2050 or 2100.

254 Naturally occurring minerals, such as the iron sulfide mackinawite, play a key role in

255 Commonly used survival analysis techniques, such as the Kaplan-Meier method, often are not appropria

256 y important for calcified marine herbivores, such as the pinto abalone (Haliotis kamschatkana).

257 rs of memory processes, sex steroid hormones such as the potent oestrogen 17beta-oestradiol have been

258 Variation in these parameters, such as the rate of tumour cell proliferation or sensiti

259 nteractions, RNAs mediate cellular processes such as the regulation of gene transcription and the enh

260 me of the calculated structural observables, such as the relative accessible surface area and the int

261 iotherapy, and to address emerging questions such as the relative value of tissue biomarkers compared

262 ur ability to link infinite building blocks, such as the ribbons of COF-76, into higher dimensionalit

263 ces many key features of ecological systems, such as the role of generalists during assembly, realist

264 concerning understudied migration pathways, such as the Sicilian route.

265 trongly related to socio-economic conditions such as the size and proximity of the nearest market, po

266 and explore large-scale population dynamics, such as the spread of antibiotic resistance.

267 e trade-off among chemical design parameters such as the surface density of enzymes, various reaction

268 pointed to the existence of New World crops, such as the sweet potato and bottle gourd, in the Polyne

269 ircuits can incorporate subcortical regions, such as the thalamus and brainstem nuclei, which mediate

270 ay an important role in population processes such as the transmission of disease and information, yet

271 n to other protein quality control pathways, such as the ubiquitin-proteasome system, mitochondria pe

272 The notable features such as the use of air that is considered as a benign ox

273 essments can be done using existing methods, such as those established for development of national su

274 the APR, including surveillance for species such as those identified during this horizon scanning ex

275 ineer crops for entirely novel environments, such as those in space travel.

276 omatic paroxysmal AF in at-risk populations (such as those with cryptogenic stroke), the refinement o

277 us complications in susceptible individuals, such as those with underlying diseases including HIV/AID

278 related to identification of core reactions, such as thresholding of expression profiles, can signifi

279 available treatments are hampered by issues such as toxicity, variable efficacy, and unsuitable dosi

280 thereby focusing the pathway on select sites such as transcriptionally active genes.

281 cting clinically relevant tumour behaviours, such as treatment response and emergence of drug resista

282 s and in response to environmental stressors such as treatment with heat, chemicals, or virus elicito

283 Although conventional genomic markers (such as tumor mutation burden and neoantigen load) and t

284 ells, while anti-inflammatory M2 macrophages such as tumor-associated macrophages (TAMs) promote tumo

285 zed by common, clinically variable symptoms, such as typical facial dysmorphisms, short stature, deve

286 However, other properties such as ultimate toughness, tensile strength, poroviscoe

287 velocities are useful for retrieving signals such as uplift along elevated viaducts of Metro lines 4

288 We conclude by proposing strategies-such as using more diverse training datasets that includ

289 Nuclear processes, such as V(D)J recombination, are orchestrated by the thr

290 f RelA and c-Rel signaling dynamic features, such as variations in duration or time-integrated activi

291 rone to responding to environmental changes, such as varied sea surface temperatures caused by storms

292 rentiating into nonmyocyte cardiac lineages, such as vascular smooth muscle cells, pericytes, and fib

293 ity and infection rates, landscape features, such as vegetation cover and water body availability, pl

294 and it is unclear whether well-studied taxa, such as vertebrates, reflect changes in wider biodiversi

295 otein, regulates various cellular functions, such as vesicle trafficking, activity of the Rab3 and Ra

296 of affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofi

297 ulation of negative regulators of cell cycle such as Wee1-like protein kinase (WEE1).

298 ve sometimes produced contradictory results, such as whether CCL2 or IL12 define effective monocyte r

299 ithin ter, and interacts with other proteins such as ZapB.

300 Receptor-like cytoplasmic kinases (RLCKs) such as ZED1, interact with ZAR1 and provide specificity