ライフサイエンスコーパス: suicidality

1 em (any anxiety, depression, or self-harm or suicidality).

2 onale for its possible use in treating acute suicidality.

3 ction of psychiatric hospitalizations due to suicidality.

4 nd postmortem brain samples of patients with suicidality.

5 ors, was one of the increased biomarkers for suicidality.

6 ts that suicide terrorism is attributable to suicidality.

7 psies, is that suicide attacks are caused by suicidality.

8 ck of efficacy or worsening of depression or suicidality.

9 knowledge of risk and resilience factors for suicidality.

10 r disorder), a high-risk population prone to suicidality.

11 ndividuals, such as those with some level of suicidality.

12 specific phobia, severe role impairment, and suicidality.

13 ly expressed gene biomarkers of relevance to suicidality.

14 the prevalence ratio (PR) was calculated for suicidality.

15 sychiatric comorbidity, role impairment, and suicidality.

16 psychiatric disorders, role impairment, and suicidality.

17 lationship appears to exist between NSSI and suicidality.

18 follow-up on all measures of depression and suicidality.

19 inst placing a black box warning on AEDs for suicidality.

20 ing the exact onset and duration of NSSI and suicidality.

21 dolescent nonsuicidal self-injury (NSSI) and suicidality.

22 y influences the risk for treatment-emergent suicidality.

23 order, for association with new or worsening suicidality.

24 bolism and a primary genetic risk factor for suicidality.

25 SNPs revealed a gene-by-sex interaction with suicidality.

26 significantly associated with improvement in suicidality.

27 were significantly associated with new-onset suicidality.

28 fe events, severity of major depression, and suicidality.

29 t patterns, aberrant behavior, appetite, and suicidality.

30 isorders were not proximally associated with suicidality.

31 associated with a modestly increased risk of suicidality.

32 increased risk of adverse events, including suicidality.

33 ing their potential utility as biomarkers of suicidality.

34 icularly for enhanced clinical monitoring of suicidality.

35 red evaluations that included assessments of suicidality.

36 t of manic or depressive symptoms, or reduce suicidality.

37 ontrol, sexual risk behavior, pregnancy, and suicidality.

38 order were associated with a higher level of suicidality.

39 or 5 (mGluR5) in pathophysiology of PTSD and suicidality.

40 e withdrawal symptoms such as depression and suicidality.

41 s were significantly associated with current suicidality.

42 factors for suicide and SI and treatment of suicidality.

43 m ratings were significantly associated with suicidality.

44 l threshold depression rating that predicted suicidality.

45 e found variations for various severities of suicidality.

46 lly explain the association between pain and suicidality.

47 dividuals had a higher prevalence of overall suicidality.

48 nditions, including anxiety, depression, and suicidality.

49 osure were associated with increased risk of suicidality.

50 great promise in treatment of depression and suicidality.

51 wnstream pathways related to inflammation in suicidality.

52 ed circadian rhythms and a high incidence of suicidality.

53 % for predicting future hospitalizations for suicidality.

54 nt subgroups and subgroups with a history of suicidality.

55 otal of 2683 individuals were diagnosed with suicidality 1 year before or after giving birth for a to

56 1-d lag [OR = 1.24 (95% CI: 1.02, 1.52)] and suicidality 1-d lag [OR = 1.44 (95% CI: 1.03, 2.02)]}.

57 sive episode, 35.4% and 14.7%, respectively; suicidality, 20.2%; generalized anxiety disorder, 7.9%;

58 rders (30.6% [N=22] versus 10.7% [N=3]), and suicidality (22.2% [N=16] versus 3.6% [N=1]).

59 istical superiority to treatment as usual on suicidality (23% versus 74%), diagnostic status (13% ver

60 t by 18 studies comprising 583 patients with suicidality, 315 patients without suicidality, and 845 h

61 , in Finns, TPH genotype was associated with suicidality, a pathophysiological mechanism that may inv

62 previous depressive episodes, male sex, and suicidality additionally predicted poor 1-year outcomes.

63 ased risk of completed suicide and to assess suicidality adequately in patients with chronic fatigue

64 treatment of depression in late life and how suicidality affects treatment response.

65 ealth would be significantly associated with suicidality after adjusting for mental health variables

66 ical health is significantly associated with suicidality, after adjusting for depression, was specifi

67 olymorphism in intron 7 of the TPH gene with suicidality, alcoholism, and the Karolinska Scales of Pe

68 ce abuse and depressive symptoms (other than suicidality), all of the suicidality measures remain sig

69 Suicidality also was reduced significantly (P < .05).

70 Twenty-nine participants (12.83%) reported suicidality, although only 11 of these were significantl

71 18 identified over 90% of the patients with suicidality, although there was also a high rate of fals

72 for an association between substance use and suicidality among ASMM from the 2015 and 2017 Youth Risk

73 al point for targeted interventions reducing suicidality among ASMM.

74 REB1 were associated with treatment-emergent suicidality among men with depression, extending an obse

75 a platform for identifying genetic risk for suicidality among PLWHA.

76 This study documents the burden of nonfatal suicidality among US blacks, notably Caribbean black men

77 n subjects with MDD and were associated with suicidality and anhedonia.

78 ug Administration issued a warning regarding suicidality and antiepileptic drugs based on meta-analys

79 phic effects, are decreased in expression in suicidality and are known targets of the anti-suicidal m

80 Studies also investigated suicidality and cultural factors underlying coping.

81 ings for many depressive symptoms (including suicidality and depressed mood) and lower ratings for th

82 Outcomes included suicidality and diagnoses of depression, anxiety disorde

83 ed to test the relative associations between suicidality and dimensional and categorical depression m

84 s review will provide a brief description of suicidality and discuss the contribution of upstream and

85 showed significant and similar reductions in suicidality and functional impairment.

86 We examined associations between suicidality and genotypes that predict plasma efavirenz

87 cidality compared with both patients without suicidality and healthy control subjects (p < .05 for ea

88 cidality compared with both patients without suicidality and healthy controls (p < .01 for each).

89 , he puts sole focus on the personal side of suicidality and ignores the individual's context.

90 India, there were more than 200 people with suicidality and more than 15 suicide attempts.

91 o the TPH gene may predispose individuals to suicidality and other behaviors thought to be influenced

92 okine levels in patients with versus without suicidality and patients with suicidality versus healthy

93 ies found no evidence of increased risks for suicidality and seizures.

94 oyment, and making progress in symptoms like suicidality and self-harming.

95 between sociodemographic factors and overall suicidality and severity.

96 luded questions relating to the phenomena of suicidality and sexual abuse, to test the hypothesis tha

97 akathisia/restlessness, anxiety, depression, suicidality and somnolence/sedation.

98 ographic and other risk factors for reducing suicidality and suicide deaths in India.

99 ant feature of several psychiatric diseases, suicidality and violent behaviour.

100 ggregating the previous four traits (termed "suicidality") and second, genetically, by using genomic

101 CFI-S, Convergent Functional Information for Suicidality) and for anxiety and mood (SASS, Simplified

102 oderate, high, and overall (representing any suicidality), and examined for sociodemographic differen

103 ews, 5.1% (95% CI 4.7-5.6) had some level of suicidality, and 0.3% (0.2-0.4) had at least one suicide

104 ients with suicidality, 315 patients without suicidality, and 845 healthy control subjects.

105 of cocaine and amphetamine use on mortality, suicidality, and blood borne virus incidence.

106 suicidal predisposition, indicated by prior suicidality, and controlling for prior psychiatric disor

107 empters display more severe psychopathology, suicidality, and interpersonal difficulties and are more

108 including BPD symptomatology, mood symptoms, suicidality, and neurocognitive impairment.

109 cide ideation, use of crisis services due to suicidality, and reasons for living.

110 Forty percent of transgender persons endorse suicidality, and the rate of self-injurious behavior and

111 and IL-6 were most robustly associated with suicidality, and these cytokines may help distinguish su

112 borrowing and indebtedness, legal problems, suicidality, and treatment for mental health and gamblin

113 rtant as emerging evidence suggests NSSI and suicidality are distinct yet related clinical phenomena

114 gies diverse, but symptoms such as guilt and suicidality are impossible to reproduce in animal models

115 ion-based, nationally representative data on suicidality are not readily available to plan and implem

116 selective serotonin reuptake inhibitors and suicidality are presenting major difficulties for clinic

117 ment, a range of mental health disorders and suicidality are proposed as diagnostic features of traum

118 Four lifetime symptoms of suicidality as measured by the Diagnostic Interview Sche

119 e episode, generalized anxiety disorder, and suicidality, as well as presence and severity of postdep

120 nces of bullying and symptoms of burnout and suicidality assessed at the time of their board certific

121 stration reports regarding increased risk of suicidality associated with AED treatment, the current s

122 symptom load explained most of the risk for suicidality associated with current psychiatric disorder

123 groups of patients based on their levels of suicidality at baseline and during treatment (those with

124 were included in the risk ratio analysis of suicidality because 4 trials had no events in the drug o

125 ication or whether such medication decreases suicidality because of improvements in insomnia.

126 and after diagnosis (IRR, 2.2-10.9) and for suicidality before epilepsy diagnosis (IRR, 3.1-4.5) and

127 sue of biological context and differences in suicidality between the two genders.

128 viduals that are more homogenous in terms of suicidality biology and behavior.

129 chiatric disorder is a major risk factor for suicidality but has poor positive predictive value.

130 ficant positive association between AEDs and suicidality but voted against placing a black box warnin

131 dditionally, we examined whether subtypes of suicidality can be identified based on mental state at t

132 apps, Convergent Functional Information for Suicidality (CFI-S) and Simplified Affective State Scale

133 associated with a 2-fold increased hazard of suicidality compared with a regimen without efavirenz.

134 nd postmortem brain samples of patients with suicidality compared with both patients without suicidal

135 was significantly decreased in patients with suicidality compared with both patients without suicidal

136 0]; p<0.0001) had an increased risk for high suicidality, compared with their corresponding counterpa

137 mainly by melancholic symptoms, retardation, suicidality, depersonalization, typical diurnal variatio

138 after co-occurring psychiatric disorders and suicidality during adolescence were controlled statistic

139 nted for by co-occurring Axis I disorders or suicidality during adolescence.

140 he risk for Axis I psychiatric disorders and suicidality during early adulthood.

141 ectors from the NMHS obtained information on suicidality (during the past month) from a community sam

142 pression, substance abuse), higher levels of suicidality (e.g., ideation), and poorer interpersonal f

143 .7; for 1999, OR, 3.9; 95% CI, 1.9-7.8), and suicidality (eg, attempted suicide [for 1997, OR, 7.6; 9

144 ding pain, was significantly associated with suicidality even after adjusting for treatment and depre

145 not associated with increased depression or suicidality events compared with placebo.

146 d a Public Health Advisory about the risk of suicidality for pediatric patients taking antidepressant

147 tion between more externalizing symptoms and suicidality (for a change of 1 SD in symptoms, OR, 1.42;

148 suicide, and a rating of "much worsening of suicidality" from baseline.

149 f access to guns at home was associated with suicidality (grades 9-12: P<.001) and violence (grades 7

150 Notably, PER1, increased in expression in suicidality, had an AUC of 84% for predicting future hos

151 hensive body of work on blood biomarkers for suicidality has previously been published by our group.

152 ation of bipolar disorder (eg, one including suicidality) highlight the role of adverse environmental

153 The suicidality hypothesis could be applied to other situati

154 shed much needed light in the area of female suicidality, identify useful objective predictors and he

155 study of BDD's course, the authors examined suicidality in 185 subjects for up to 4 years.

156 ity Rating Scale (AIRS), and its relation to suicidality in a high-risk sample.

157 g the potential association between pain and suicidality in adolescents aged 10-19 years.

158 ing whether treatment of insomnia may reduce suicidality in adults with depression.

159 on as an important potential risk factor for suicidality in adults with this condition.

160 thors' knowledge, has prospectively examined suicidality in BDD.

161 (i.e., mixed state), that is associated with suicidality in bipolar patients.

162 ADHD medication use was associated with less suicidality in children with more externalizing symptoms

163 d and Drug Administration warnings regarding suicidality in children, adolescents, and young adults m

164 nosis of psychosis, depression, anxiety, and suicidality in each of the 3 years before and after the

165 association of the TPH 17 779C (L) allele to suicidality in impulsive offenders reported previously w

166 ion (SI) and for future hospitalizations for suicidality in independent cohorts, leading to the ident

167 r, LHFP appears to be a strong predictor for suicidality in males with depression.

168 r disorder were studied to determine whether suicidality in mania is associated with increasing depre

169 s risk for antidepressant treatment-emergent suicidality in men with major depressive disorder, but i

170 d clinical information (apps) predictors for suicidality in men.

171 otional withdrawal, counter the emergence of suicidality in patients with schizophrenia spectrum diso

172 ed that the 2004 black box warning regarding suicidality in pediatric patients receiving antidepressa

173 d a public health advisory about the risk of suicidality in pediatric patients taking selective serot

174 d a public health advisory about the risk of suicidality in pediatric patients taking selective serot

175 tion does not appear to increase seizures or suicidality in persons with epilepsy.

176 e measurement of both sexual orientation and suicidality in population-based samples.

177 t activity have been noted to be a marker of suicidality in psychiatric patients.

178 ew to synthesise the available literature on suicidality in PwP and highlight areas for potential int

179 The authors' goal was to examine suicidality in relation to acute symptom remission in in

180 essive symptoms, diagnosable depression, and suicidality in relation to stressful life events than in

181 ciated with susceptibility to depression and suicidality in response to stressful life events.

182 s predictions of future hospitalizations for suicidality in the bipolar cohort (receiver-operating ch

183 moved and physicians confront depression and suicidality in their peers, they are more likely to reco

184 oute induced a rapid improvement in mood and suicidality in these refractory depressed patients, supp

185 pite this, there is limited understanding of suicidality in this population.

186 We found an increased risk for overall suicidality in women versus men (odds ratio [OR] 1.54 [9

187 de), our apriori primary end point, predicts suicidality in women.

188 ased risk of suicidal ideation and behavior (suicidality) in pediatric patients.

189 ressants and suicidal behavior and ideation (suicidality) in youth, adverse events from pediatric cli

190 future as well as past hospitalizations with suicidality, in a live cohort of bipolar disorder subjec

191 rs to predict future hospitalizations due to suicidality, in male bipolar disorder participants.

192 Suicidality incidence per 1000 person-years was 8.08 (47

193 ality disorder, substance use disorders, and suicidality (including recurrent thoughts of death, suic

194 Although pain and suicidality (including suicidal ideation, behaviour, and

195 Recent genetic studies for suicidality, including four independent GWAS, have not r

196 justed analyses based on 12 genotype levels, suicidality increased per level in exposed (hazard ratio

197 re inversely proportional to the severity of suicidality independent from depression severity.

198 imply that whenever past or current NSSI or suicidality is identified, primary care clinicians condu

199 Suicidality is linked to mental pain, which is modulated

200 Suicidality is linked with mixed manic states and may be

201 ance abuse, sexual activity, depression, and suicidality is needed with appropriate anticipatory guid

202 The relationship between efavirenz use and suicidality is not well-defined.

203 its high prevalence and known risk factors, suicidality is often undetected.

204 infections to neuropsychiatric symptoms and suicidality is only beginning to be explored.

205 ssociations between pain characteristics and suicidality is sparse and inconclusive, and potentially

206 Report Questionnaire expanded to include two suicidality items from 810 displaced women living in ref

207 Unrecognized and thus untreated suicidality leads to substantial morbidity and mortality

208 sting drugs used to treat mood disorders and suicidality (lithium, clozapine and omega-3 fatty acids)

209 few studies suggesting that pain can predict suicidality longitudinally.

210 dentify blood gene expression biomarkers for suicidality, looking at differential expression of genes

211 OR, 26.7 [95% CI, 4.3-52.5]; P < .001), and suicidality (males only; OR, 18.5 [95% CI, 6.2-55.1]; P

212 Overall, suicidality may be underlined, at least in part, by biol

213 ity, difficulties in emotion regulation, and suicidality may characterize adolescent expression of bo

214 h ARRB1 and GSK3B decreases in expression in suicidality may provide a synergistic mechanistical corr

215 ymptoms (other than suicidality), all of the suicidality measures remain significantly associated wit

216 is significantly associated with each of the suicidality measures.

217 as moderate to high risk suicidality on the suicidality module of the Mini Neuropsychiatric Intervie

218 of adults aged 18 years and older using the suicidality module of the Mini-International Neuropsychi

219 ction of psychiatric hospitalizations due to suicidality (n=24).

220 asures, considered an indicator of "clinical suicidality." Neither objective severity of depression n

221 High suicidality, nonsuicidal self-injury, and poor family fu

222 ers (odds ratio=1.65, 95% CI=1.25-2.18), and suicidality (odds ratio=2.21, 95% CI=1.47-3.31) than the

223 l health disorder, subthreshold symptoms, or suicidality on all three study occasions (sustained good

224 rticipants, 124 (8.6%) subsequently reported suicidality on at least 1 visit; these individuals were

225 cidal risk (defined as moderate to high risk suicidality on the suicidality module of the Mini Neurop

226 association between socioeconomic status and suicidality or depressed mood reported at each week of t

227 d in randomized trials is explained by prior suicidality or familial predisposition to psychiatric di

228 onal capacity, quality of life, reduction of suicidality or hospitalizations, and harms.

229 ssession [OR, 5.6; 95% CI, 1.7-18.3]), prior suicidality [OR, 2.9; 95% CI, 1.7-4.9], aspects of prior

230 ing a history of any mental health disorder, suicidality, or any combination of the 2.

231 had adverse reactions related to self-harm, suicidality, or harm to others.

232 of >/= 4; hospitalization for depression or suicidality; or discontinuation for lack of efficacy or

233 authors assessed patients' past and current suicidality, other psychopathology, treatment, and remis

234 ificantly associated with treatment-emergent suicidality overall.

235 e showed significant evidence for linkage to suicidality (P=.006 in unaffected sib pairs), severe sui

236 ), mood (especially, depression, apathy, and suicidality), personality and behavior (especially poor

237 = .52, p = .005; ACC: r = .53, p = .004) and suicidality (PFC: r = .40, p = .037; ACC: r = .38, p = .

238 dly alleviate depressive symptoms and reduce suicidality, possibly by decreasing hyperactivity in the

239 markers that have all around evidence (track suicidality, predict it, are reflective of biological pr

240 The men-to-women ratio of overall suicidality prevalence for India was 0.68 (range 0.55-0.

241 d states, we calculated the age-standardised suicidality prevalence for men and women, men-to-women r

242 en and women, men-to-women ratio of weighted suicidality prevalence, ratio of suicidality to suicide

243 story of mental illness without a history of suicidality (prevalence ratio [PR], 1.13; 95% CI, 0.98-1

244 ethodical, anchored approach to categorizing suicidality provides an accurate and comprehensive ident

245 d hepatitis C infection, poor mental health (suicidality, psychosis, depression, and violence), and i

246 apture of AEs of special interest, including suicidality, psychotic disorder, manic symptoms, cardiov

247 cessation itself or reflects depression and suicidality rates in smokers, independent of treatment.

248 ontrolling for overall depression (excluding suicidality-related item), and predicted subsequent leve

249 d be designed to assess whether increases in suicidality result from CNS impairments from a given hyp

250 , prioritization and validation for tracking suicidality, resulting in a Top Dozen list of candidate

251 Suicidality risk at T2 appeared similarly elevated, but

252 eta-analysis was conducted to obtain overall suicidality risk estimates for each drug individually, f

253 A significant disproportionality signal for suicidality (ROR, 1.63; 95% CI, 1.47-1.81) and psycholog

254 96, 2.01) vs. 0.85 (95% CI: 0.62, 1.17)] and suicidality same day [OR = 1.98 (95% CI: 1.22, 3.23) vs.

255 pport of previously published biomarkers for suicidality (SAT1, MARCKS and SKA2).

256 suicidality effects of ketamine on all three suicidality scales/subscales (linear mixed model, fixed

257 disturbance, including risk-taking behavior (suicidality, self-mutilation, and sexual aggression).

258 seline of severe depression, manic symptoms, suicidality, subsyndromal mood episodes, and sexual abus

259 identified novel potential therapeutics for suicidality, such as ebselen (a lithium mimetic), pirace

260 ts or biomarkers for drugs known to mitigate suicidality, such as omega-3 fatty acids, lithium and cl

261 ut leukotriene receptor-modifying agents and suicidality/suicide, but because these were based on cas

262 composite measure of reporting at least one suicidality symptom was also assessed.

263 tients hospitalized without specification of suicidality, the lifetime risk of suicide was 4.0%.

264 Women are under-represented in research on suicidality to date.

265 of weighted suicidality prevalence, ratio of suicidality to suicide deaths, and ratio of suicide atte

266 The relationship of physical well-being to suicidality underscores the need for a multidisciplinary

267 Univariate analyses found suicidality unrelated to age or sex but positively assoc

268 chiatric symptoms, psychosis, depression, or suicidality using a gradual titration (1-mg daily dose).

269 alence and sociodemographic differentials of suicidality using data from the National Mental Health S

270 ere significantly decreased in patients with suicidality versus control subjects (p < .05).

271 versus without suicidality and patients with suicidality versus healthy controls.

272 fficult-to-treat components (e.g. cognition, suicidality, violence) of the illness.

273 y significantly higher levels of dependency, suicidality, violence, impulsivity, substance use proble

274 ce of suicide in those ever hospitalized for suicidality was 8.6%.

275 Relation to suicidality was assessed by regression of suicide attemp

276 ceptual abnormalities, poor orientation, and suicidality was associated with an increased risk for ho

277 Suicidality was categorised as low, moderate, high, and

278 rticipants to efavirenz-containing regimens; suicidality was defined as reported suicidal ideation or

279 Suicidality was defined as suicidal ideation or attempte

280 Among 1833 participants, suicidality was documented in 41 in exposed analyses, an

281 The prevalence of overall suicidality was higher in women (6.0% [5.4-6.6]) than in

282 The prevalence of overall suicidality was highest in those aged 40-49 years among

283 Suicidality was measured with the Hamilton Depression Ra

284 Suicidality was more common in mixed than manic bipolar

285 that insight may be associated with greater suicidality was partially supported.

286 atus of the TPH A779C allele as a marker for suicidality was replicated and linkage with alcoholism a

287 Suicidality was unrelated to age, age at diagnosis, sex,

288 rious samples and manifestations of pain and suicidality, we found that pain approximately doubles th

289 ers, major depressive disorder, and rates of suicidality were determined and compared for individuals

290 der, recent mental health specialty care, or suicidality were excluded.

291 PRINCIPAL FINDINGS: Patients presenting with suicidality were recruited from the Emergency Department

292 Past, current, and recurrent suicidality were significantly more common among patient

293 iated with impairment in role functioning or suicidality were strong predictors of perceived need.

294 nergy, minimal sleep disruption, and greater suicidality, while typical-onset patients had more sever

295 L2, predicted future hospitalizations due to suicidality with an AUC of 89%, and the panel of 50 vali

296 50) predicted future hospitalizations due to suicidality with an AUC of 94%.

297 0.98-1.29) and adolescents with a history of suicidality with or without a history of mental illness

298 sories regarding the potential for pediatric suicidality with selective serotonin reuptake inhibitor

299 tudies were too small or too short to assess suicidality with SSRIs or SNRIs.

300 Five studies investigated self-harm or suicidality, with conflicting results.