ライフサイエンスコーパス: suppression

1 corin as the molecular basis for tumorigenic suppression.

2 mononuclear cells (PBMC and LNMC) during ART suppression.

3 ) neurons contribute to PVH-mediated feeding suppression.

4 of drugs that release WT p53 and allow tumor suppression.

5 roduce antinociception with less respiratory suppression.

6 presenting cell activity is a target of Treg suppression.

7 the TME and can reverse ADO-mediated immune suppression.

8 iring cell viability as a tradeoff for tumor suppression.

9 reased T cell infiltration, and tumor growth suppression.

10 isms that govern appetitive behavior and its suppression.

11 95% CI, .31-.82]) was the primary barrier to suppression.

12 health by metabolic disruption and immunity suppression.

13 ibody nivolumab, has shown efficacy in tumor suppression.

14 g the interpulse interval led to oscillation suppression.

15 ent care visits, retention in care and viral suppression.

16 potential mechanism of loading-driven tumor suppression.

17 nd 2.09 (95% CI, 1.18-3.70) during long-term suppression.

18 ysis and impaired insulin-mediated lipolysis suppression.

19 by several successive steps of recombination suppression.

20 a specific context, I measured peri-saccadic suppression.

21 needs of people living with HIV beyond viral suppression.

22 Abstinence was associated with viral suppression.

23 redicted to be important for Rheb-signalling suppression.

24 f GILZ, thereby maintaining effective immune suppression.

25 echanism of sensory selection and distractor suppression.

26 facilitation, untuned-suppression, and tuned-suppression.

27 ent the importance of these domains in tumor suppression.

28 ing infection rate scenarios, including full suppression (0.001%), partial suppression (1%), mitigati

29 including full suppression (0.001%), partial suppression (1%), mitigation (10%), and do nothing (80%)

30 ingulate cortex (ACC) and a later beta power suppression (13-22 Hz, ~350 ms) in prefrontal and audito

31 an integrated strategy to achieve HIV viral suppression, 1305 MSM were screened across four geograph

32 vebirths, classified as reflecting sustained suppression (31 [30%]), rebound viraemia (55 [53%]), and

33 the primary outcome of retention with viral suppression, a difference of 13.9% (95% CI 6.4-21.2; p<0

34 agy pathway, thereby affecting the silencing suppression activity of p3.

35 to preserve VHL function and lacking glioma suppression activity.

36 l landscape in children exhibiting long-term suppression after early treatment, particularly in Sub-S

37 t for future preclinical studies of nonsense suppression agents in RTT.

38 ion while mitigating disease burden, and 2) "suppression," aiming to drastically reduce SARS-CoV-2 tr

39 time to treatment failure and time to viral suppression among 1419 drug-naive patients in the Swiss

40 aIRR of 1.22 (95% CI, .93-1.60) during early suppression and 2.09 (95% CI, 1.18-3.70) during long-ter

41 lth by providing enhanced nutrition, disease suppression and abiotic stress resistance, and have pote

42 the major mechanism of tumor-induced immune suppression and as an underestimated barrier to successf

43 HDAC5) are required for loading-induced Sost suppression and bone formation.

44 ciated with systemic inflammation and immune suppression and have been associated with a poor outcome

45 ing intermediate outcomes, such as virologic suppression and hepatitis B e-antigen (HBeAg) or hepatit

46 plasma in individuals with incomplete viral suppression and known neurocognitive status.

47 xidation, and that PA relieves AHL4-mediated suppression and promotes TAG degradation.

48 g VISTA- and PD-L1-signaling relieved immune suppression and reduced br-met burden.

49 seline in sensory status, including depth of suppression and stereopsis of those treated with binocul

50 radiation injury to bone marrow-both direct suppression and stochastic effects, leading to neoplasia

51 STs in stimulus-specific adaptation, forward suppression and tuning-curve adaptation, as well as the

52 tection, improved angiogenesis, inflammatory suppression, and cell cycle reentry as agrin's mechanism

53 animals prior to ART initiation, during ART suppression, and following viral rebound, and we compare

54 air, replication fork maintenance and tumour suppression, and its therapeutic relevance.

55 theranostic nanomedicine for efficient tumor suppression, and more importantly, inhibition of neutrop

56 s, acute inflammation, sepsis-related immune suppression, and sepsis-related organ failure.

57 chanisms are recruited during volitional tic suppression, and that they prevent expression of the tic

58 eCRF mechanisms: tuned-facilitation, untuned-suppression, and tuned-suppression.

59 5-mediated hSTAT2 degradation and interferon suppression, and viral infection under interferon-compet

60 of people living with HIV on ART with viral suppression; and proportion of HIV-negative men circumci

61 Rates of virologic suppression are lower in the total cohort among those wi

62 Lipid delocalization and ion suppression are two major effects that can lead to misin

63 ere we review the evidence for recombination suppression around mating-type loci in fungi, sometimes

64 s, and they had striae and secondary adrenal suppression as side effects of steroids.

65 combinatorial strategies to overcome immune suppression associated with the tumor microenvironment.

66 The secondary endpoints included virological suppression at 48 weeks according to the US Food and Dru

67 nancy is associated with not achieving viral suppression before giving birth and increased mother-to-

68 In on-treatment analysis, suppression below 1,000 copies/mL was 89.0% at month 12

69 infected cells, and the time to reach viral suppression below a defined detection threshold.

70 ent evidence for expansions of recombination suppression beyond mating-type genes in fungi ('evolutio

71 We assumed POC monitoring increased viral suppression by 9 percentage points, enrolment into commu

72 among men, eliminating disparities in viral suppression by gender.

73 protein synthesis was not required for gene suppression by HDACi.

74 we further analyze Abeta42 toxicity and its suppression by PI3K activation in in vitro assays with S

75 sures, including vector control and inoculum suppression, by removing host plants.

76 Upfront reflux monitoring off acid suppression can limit unnecessary PPI use and guide pers

77 esistance, neglecting the intrinsic dendrite-suppression capability of SSEs.

78 To achieve a high dendrite-suppression capability, SSEs should be thermodynamically

79 ompared women with elevated VL after initial suppression (cases, n = 80) incidence-density matched to

80 elivery of ART significantly increased viral suppression compared with clinic-based ART, particularly

81 months, community-based ART increased viral suppression compared with the clinic group (306 [74%] vs

82 s such as tolerance, dependence, respiratory suppression, constipation, and abuse liability detract f

83 similar to the North American prairie, fire suppression contributes to local plant extinctions.

84 sponse in the superficial layers (repetition suppression) coupled with a heightened response in the d

85 These findings suggest that loss of HIV suppression due to donor-derived HIV superinfection migh

86 Despite success achieving viral load suppression during pregnancy, women living with perinata

87 Data with self-terms revealed an interocular suppression effect, in which the responses to the stimul

88 For this group of analytes, however, ion suppression effects have been described to strongly favo

89 etastasis-correlated gene networks of immune-suppression, epithelial-mesenchymal transition (EMT) and

90 azoparib in murine xenografts provides tumor suppression equivalent to a month of daily dosing of tal

91 strepsirrhines whereas several recombination suppression events moved the PAB and shortened the pseud

92 n ocular complications of HIV-related immune suppression, few studies have examined the prevalence an

93 alpha-Band suppression following tactile stimulation was lateralize

94 n for 6 months, suppression for 2 months, or suppression for 1 year.

95 andemic: no action, mitigation for 6 months, suppression for 2 months, or suppression for 1 year.

96 ed as early as 4 weeks of age, and transgene suppression for the first 4 or 12 weeks of life prevente

97 developed to balance between aging and tumor suppression, for example, by differentially regulating c

98 shaped by oncogenic drivers promotes immune suppression from the earliest stages of tumor inception

99 tes (p53-5KR) diminished its remaining tumor suppression function.

100 evidence reveal dual roles for GJs, in tumor suppression, generally referred to as dormancy, and prog

101 ecreased stimulus selectivity in IC, whereas suppression had no effect.

102 PD-L1 induced immune suppression has increasingly gained attention in clinica

103 ffect of antiretroviral therapy (ART) on HIV suppression, immune activation, and quality of life (QoL

104 is critical for cellular homeostasis, tumor suppression, immunity, and gametogenesis.

105 o-tyrosine could not outcompete near-cognate suppression in an RF1-deficient expression host and ther

106 Here, we show that this arousal-related suppression in decision bias acts on both conservative a

107 anisms being proposed for p53-mediated tumor suppression in different contexts.

108 ficantly reduces sustained spectral surround suppression in excitatory cells, indicating a dominant c

109 drug uptake and simultaneously enhance viral suppression in HIV-1-infected macrophages.

110 a major threat to achieving long-term viral suppression in HIV-positive individuals.

111 (HIVDR) is a barrier to sustained virologic suppression in low- and middle-income countries (LMICs).

112 atory review for use in maintenance of viral suppression in people with HIV.

113 silencing did not exhibit the stress-induced suppression in pulsatile luteinizing hormone secretion o

114 Impaired Treg suppression in the absence of ERbeta was associated with

115 viral shedding >=400 copies/mL despite viral suppression in the blood.

116 hed roles in epigenetic regulation and tumor suppression in the endocrine pancreas; however, intrigui

117 cycling in the Pinus-dominated site, but no suppression in the Quercus-dominated site.

118 es, absence of GI neuron activity after AMPK suppression in the VMN had no impact on the counterregul

119 emonstrate a significant reduction in neural suppression in young adults with autism spectrum disorde

120 Furthermore, ssbp1 suppression in zebrafish induced signs of nephropathy an

121 nificantly larger RF sizes and less surround suppression, independent of stimulus eccentricity or con

122 Suppression is a common phenomenon and this study provid

123 This suppression is abolished if DG expression is silenced, a

124 A significant tumor suppression is achieved by Fenton reaction-mediated ferr

125 Attaining viral suppression is crucial in reducing new diagnoses and spa

126 To establish how essential maternal hepcidin suppression is for embryo iron homeostasis, we mimicked

127 This study suggests that M-current suppression is important for stable encoding of specific

128 pectations about object weight and that this suppression is mediated by the posterior superior tempor

129 , the contribution of this function to tumor suppression is poorly understood.

130 Monitoring of virological suppression is recommended at 6 months of treatment and

131 Thus, weaker neural suppression is reflected in visual task performance and

132 iquitylation during elongation and that this suppression is relieved when CMGs converge, leading to C

133 This stage-specific HIF suppression is required for normal B cell development be

134 Its suppression is thus of great interest, but the necessary

135 The primary outcome was combined viral suppression (<200 copies per mL) and retention at 12 mon

136 were presumed not to be in care, viral load suppression (<200 copies per mL) was based on the last v

137 The suppression magnitude varied depending on visual area, a

138 Antibiotic suppression markedly accelerated MHV-68 pathology causin

139 Suppression may occur directly at the level of host-path

140 ults signal the need for sustained stringent suppression measures as well as sustained efforts to tar

141 This is achieved through a subtractive-suppression mechanism, mediated largely by LP-to-A1 axon

142 Moreover, alpha-band suppression occurred at the time of, or after, the produ

143 Similar bias suppression occurred when evidence was drawn from memory

144 -releasing molecule 2 treatment caused rapid suppression of 2B6 enzyme activity, significant HMM spec

145 Posttransplant, sustained suppression of 3 of 3, 4 of 6, and 8 of 8 DSA (cases 1-3

146 This effect appears to be driven by GC suppression of 3beta-HSD1 substrate.

147 Flexible initiation or suppression of actions to avoid aversive events is cruci

148 merular hyperfiltration and albuminuria, and suppression of advanced glycation end-product signalling

149 We demonstrate QEC of an encoded qubit with suppression of all logical errors, in quantitative agree

150 Suppression of AMPKalpha1 by using nano-sized polymeric

151 ary, we demonstrate here that brain-specific suppression of AMPKalpha2 isoform impairs cognition and

152 In conclusion, smoking may cause suppression of appetite but smokers tend to have other u

153 ytotoxicity in neural cells with concomitant suppression of As-induced ER stress.

154 Substantial suppression of basophil activation was required to maint

155 as a scaffold for ATG16L1 necessary for the suppression of BAX activation and induction of the intri

156 ofeedback training can facilitate volitional suppression of beta bursts in sensorimotor cortex in hea

157 ofeedback training in facilitating voluntary suppression of beta bursts to speed up movement initiati

158 enrichment is enabled by aldafermin-mediated suppression of bile acid synthesis and, in particular, d

159 The suppression of bone formation is a hallmark of multiple

160 Suppression of both RIG-I and TLR4 signaling pathways, e

161 identifies a new role for dSarm and glia in suppression of bystander neuron function after injury an

162 We found clear evidence of EM fungal suppression of C and N cycling in the Pinus-dominated si

163 cally, interference with HDAC1/-2 elicited a suppression of c-Myc protein levels and a concomitant in

164 cluding facilitating bacterial colonization, suppression of callose deposition, and targeting the pla

165 N-induced cellular proteins that mediate the suppression of cccDNA transcription by the cytokine, we

166 activity and partially attenuated IFN-alpha suppression of cccDNA transcription.

167 from Pcsk6(-/-) versus control mice revealed suppression of contractile SMC markers, extracellular ma

168 nstrated that proinflammatory cytokines, via suppression of COUP-TFII level, induce VEGF-C overexpres

169 Our results therefore imply that suppression of de novo infection may reduce the risk of

170 Suppression of early-stage neuronal death by AAV-YAPdelt

171 caspase inhibitors result in CED-3-dependent suppression of embryonic lethality and meiotic chromosom

172 of the entire C19MC cistron and resulted in suppression of EMT associated genes.

173 etabotropic NMDARs and postsynaptic Panx1 in suppression of facilitated glutamate neurotransmission.S

174 al PV(+) interneurons induces a long-lasting suppression of GABAergic synaptic transmission, which de

175 hand-in-hand with a reshaping rather than a suppression of gender norms, with the emergence of new a

176 t loss was associated with increases in mean suppression of glucose production from baseline, by 7.04

177 rd-predictive cues is accompanied by a rapid suppression of glutamate release.

178 ing proteinopathies rather than pre-existing suppression of glymphatic influx.

179 ar, the most successful strategies to induce suppression of graft rejection relies on inhibition of T

180 rophage phagocytosis of debris, resulting in suppression of HCC tumor growth.

181 patients' hyperglycemia through significant suppression of hepatic glucose production.

182 Moreover, we found that suppression of hepcidin via KY1070 modulates ferroportin

183 treatment of hepatocytes induced a prolonged suppression of human and duck hepatitis B virus cccDNA t

184 Importantly, non-selective suppression of huntingtin was generally tolerated, howev

185 n together, these data suggest that targeted suppression of IL17RA is a promising new topical treatme

186 Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing tha

187 ty and HSC function which is reversible upon suppression of inflammation.

188 ation, including neuroprotection and broader suppression of inflammatory mediators.

189 , CCK+ inputs undergo depolarization-induced suppression of inhibition (DSI) and CB1 receptor modulat

190 litate long-term memories (LTM) but also the suppression of inhibitory processes that prevent them.

191 First, mu-opioids induce a long-lasting suppression of inhibitory synaptic transmission onto OFC

192 I3K signaling through direct transcriptional suppression of IRS2, leading to reduced RTK levels and a

193 llergen challenge, which was associated with suppression of lung-specific Th2 responses long after in

194 Among those, we show that suppression of Malat1 is a hallmark of CD4(+) T cell act

195 lammation can counteract pregnancy-dependent suppression of maternal hepcidin.

196 REC8 enrichment is associated with suppression of meiotic DSBs and crossovers at the chromo

197 ncurrent activation of mitotic enhancers and suppression of meiotic enhancers in the somatic and/or m

198 teady state that supports myogenesis through suppression of metabolic endotoxemia and that Zip14 abla

199 g cells in Vbeta5-deficient mice compromises suppression of microbiota-dependent activation of CD8(+)

200 miR-31 deletion resulted in suppression of miR-31-associated EGLN3/NF-kappaB-control

201 provement of cognitive flexibility following suppression of mPFC-AcbSh activity align with the relati

202 RNAi suppression of MSH1 results in phenotype variability for

203 ted with adaptive immunity was linked to the suppression of networks for tight junction, gap junction

204 for relapsed neuroblastoma, caused long-term suppression of neuroblastoma growth in vivo, highlightin

205 -term improvements in neurological function, suppression of neuroinflammatory and oxidative stress pa

206 ed E2 appear to be due, at least in part, to suppression of neuronal FGF2 signaling, which is a known

207 For the first time, suppression of non-radiative decay pathways of a chromop

208 duction of ER stress pharmacologically or by suppression of other ER stress response pathway componen

209 ly enhanced their activity, interleaved with suppression of others.

210 to stimulate MDMX-p53 binding, and increased suppression of p21 expression.

211 Suppression of PHGDH rendered cells sensitive to MEKis,

212 models, we show that systemic or EC specific suppression of phosphoinositide recycling results in red

213 SDE15 suppression of plant immunity is dependent on CsACD2, an

214 ot retinotopically specific, suggesting that suppression of PM altered sensory integration or the dec

215 In addition, the mechanism leading to suppression of predicted sensory information remains unc

216 Previous studies have revealed consistent suppression of predicted stimulus information in sensory

217 lly during cortical ACT, (2) abnormal phasic suppression of PV GPe neuron activity was ameliorated by

218 Our data suggest that suppression of RA directly reduces arrhythmia susceptibi

219 NO66 suppression of ribosomal biogenesis via demethylase acti

220 n and this study provides novel insight into suppression of rust resistance in wheat.

221 Our modeling confirmed that suppression of SARS-CoV-2 transmission is possible with

222 endent reactive oxygen species generation by suppression of site IQ electron leak, decreased myocardi

223 mechanisms associated with biochar-elicited suppression of soilborne plant diseases and improved pla

224 elid closure itself depending on a transient suppression of spike firing.

225 1 Hz for 1 hr resulted in an almost complete suppression of spontaneous seizures in both hippocampi.

226 The suppression of storage proteins led to the elaboration o

227 the face and was expressed as the selective suppression of sustained responses to low-identity faces

228 e antibody and sulfasalazine resulted in the suppression of Th1 cytokines and a marked increase in lu

229 Suppression of the APC/C or forced APC/C activation by t

230 tion of angiogenesis, tissue remodeling, and suppression of the cytotoxic T lymphocyte (CTL) response

231 their different interaction mechanisms, the suppression of the fibril pathway can be deduced from th

232 at combining Enz plus olaparib led to better suppression of the HCC progression.

233 lergy, anti-IL-4Ralpha provided long-lasting suppression of the IgE recall response beyond antibody t

234 etome in antimiR-21-treated myocardium and a suppression of the inflammatory response and mitogen-act

235 The suppression of the KChIP3-mediated modulation of Kv4.2 c

236 ability in UBCs was partially compensated by suppression of the magnitude and duration of delayed hyp

237 The successful suppression of the offset artifacts with a narrower data

238 anomaly at low temperatures, arising from a suppression of the quantum corrections due to weak local

239 ptors aureochrome and phototropin revealed a suppression of the response of specific secondary struct

240 Our results demonstrate a significant suppression of the structural phase transitions, enhance

241 hinders electron transfer and results in the suppression of the transferred charge amount.

242 ur study revealed a role for transcriptional suppression of the tumor-intrinsic HLA class I (HLA-I) a

243 9-75.2) to 93.1% (90.2-96.0), and viral load suppression of those on ART increased from 88.7% (83.6-9

244 This is likely due to suppression of thrombin-induced phosphorylation and ther

245 ion can be used to prevent unintended immune suppression of TLR7.

246 pathway, inducing CIP, as well as attenuated suppression of tumor growth in mice.

247 PHIP knockdown produced substantial suppression of tumor growth upon intracranial implantati

248 This also resulted, in vivo, in a suppression of tumour growth and a decrease in the numbe

249 nated HMOs, whose expression correlated with suppression of two major Th2 cytokines, IL-10 and IL-13.

250 of a Th2-like phenotype in the gills and the suppression of type 1 immune responses.

251 BV-specific T-cell frequency and resulted in suppression of virus replication but failed to fully res

252 This results in subtractive suppression of visual responses and an overall enhanceme

253 w waves and off-periods-reflecting transient suppressions of neuronal activity-in the area surroundin

254 to separate specific effects (e.g. androgen suppression) of individual chemical exposures from other

255 TATEMENT Healthy human behavior requires the suppression or inhibition of errant or maladaptive motor

256 hospital and retention in HIV care and viral suppression over a 12-month period.

257 ence-density matched to women who maintained suppression over time (controls, n = 87).

258 d breath-hold examination sequences with fat suppression, performed between 2011 and 2015 were includ

259 Despite viral suppression, PHIVs have evidence of altered gut permeabi

260 Elevated weight suppression predicted future onset of AN (OR: 1.36; 95%

261 ting IFN-gamma and perforin in a coordinated suppression program over time.

262 concentrations were associated with greater suppression rates of lipolysis and lower intrahepatic li

263 o 23 days and increased community viral load suppression rates to 86%.

264 ull advantage of the chromatography-free and suppression-reducing features of this prototype instrume

265 vide a versatile platform for a local immune suppression regimen that can be applied to allogeneic ce

266 ot CD86 expression in vitro and in vivo This suppression required the HSV-1 ICP22 gene.

267 rn regulates metabolic reprogramming, immune suppression, resistance to apoptosis, angiogenesis, meta

268 bunits, thereby offering a mechanism for the suppression results.

269 04 is sensitive to microbiota, and microbial suppression reversibly decreases aortic miR-204 and impr

270 rt (range of 1 to 19 years of continuous ART suppression) showed a median viral load of 0.54 cp/ml (i

271 These adaptive choices elicited a suppression signal in the hippocampus, revealing sensiti

272 r women were also less likely to reach viral suppression than Black cisgender women (aPR: 0.55, 95%I

273 e for TFA mobile phases, which mitigates ion suppression through a similar mechanism but in a more ef

274 -galactoside-binding lectin, promotes immune suppression through T-cell inhibition, and programming o

275 eeded to treat ranged from 2.6 for virologic suppression to 17 for HBeAg seroconversion.

276 oncurrent N and P deposition alleviates this suppression to 5.8%.

277 primary end point was sustained testosterone suppression to castrate levels (<50 ng per deciliter) th

278 ls evaluated the relation of baseline weight suppression to onset risk of each eating disorder contro

279 oes, and use of these males in a large-scale suppression trial in Fresno County, California.

280 uld assess their retention in care and viral suppression under Treat All.

281 der) and (1) retention in care and (2) viral suppression using 2016 client-level RWHAP Services Repor

282 ted 6 individuals with HIV (n = 4 with viral suppression using antiretroviral [ART] therapy; n = 2 wi

283 Targeting immune suppression using checkpoint inhibition has resulted in

284 ar endothelial growth factor-mediated immune suppression via angiogenesis inhibition may augment the

285 ia patients is a significant cause of immune suppression via HO-1 induction and may underlie the susc

286 outcomes (retention in care with viral load suppression [VLS; viral load <1000 copies per mL], reten

287 3TC was noninferior in maintaining virologic suppression vs a TAF-based regimen at week 48, with no v

288 ears at ART initiation, with sustained viral suppression (VS) (<=400 copies/mL) for >=1 year were inc

289 he Index) and suboptimal retention and viral suppression (VS) outcomes.

290 feriority of DTG + FTC versus cART for viral suppression was assessed using a stratified Mantel-Haens

291 NT) for 1 additional person to achieve viral suppression was calculated.

292 In contrast, suppression was minimal in T2DM.

293 This suppression was not associated with changes in expressio

294 006), though the efficiency of cardiomyocyte suppression was variable among TAC mice.

295 Distinct from pharmacologic immune suppression, we have developed what we believe is a nove

296 Pre-conception viraemia and immune suppression were also strong risk factors for post-partu

297 urthermore, polyploidy induces recombination suppression, which correlates with altered epigenetic la

298 long with AMPK activation and mTORC1 pathway suppression, which subsequently triggered AMPK-dependent

299 , Kv7.2(S559A), which show reduced M-current suppression while maintaining a normal basal M-current a

300 ungi and their metabolic products on disease suppression with the addition of OAs.