ライフサイエンスコーパス: surfactant protein

1 r sac-like structures and production of lung surfactant protein.

2 skeleton, and as receptors for immunological surfactant proteins.

3 e by proteolysis and through interactions of surfactant proteins.

4 cells correlated with the expression of the surfactant proteins.

5 In the lungs, surfactant protein A (SP-A) and SP-D contribute to immun

6 binding capability of surfactant-associated surfactant protein A (SP-A) and surfactant protein D (SP

7 Mice lacking surfactant protein A (SP-A) are susceptible to bacterial

8 The identification of surfactant protein A (SP-A) as an important innate immun

9 The host antimicrobial agent surfactant protein A (SP-A) effectively reduced ciliary

10 In the lung, surfactant protein A (SP-A) enhanced interleukin-4 (IL-4

11 Surfactant protein A (SP-A) enhances phagocytosis of Pse

12 We previously reported that mice lacking surfactant protein A (SP-A) have increased airway hyperr

13 The current study investigated the role of surfactant protein A (SP-A) in opsonization and clearanc

14 hypothesize a central role for the collectin surfactant protein A (SP-A) in regulating the developmen

15 onization of F. novicida with lung collectin surfactant protein A (SP-A) increased bacterial associat

16 Previous studies reported that surfactant protein A (SP-A) inhibits lymphocyte prolifer

17 Surfactant protein A (SP-A) is a hydrophilic glycoprotei

18 Surfactant protein A (SP-A) is an immune modulator that

19 Surfactant protein A (SP-A) is important for immune defe

20 Surfactant protein A (SP-A) modulates host responses to

21 Surfactant protein A (SP-A) plays a critical role in the

22 Pulmonary surfactant protein A (SP-A) plays a key role in innate l

23 Surfactant protein A (SP-A) plays a role in lung innate

24 Lung surfactant protein A (SP-A) plays an important function

25 st to immobilized human fibronectin (FN) and surfactant protein A (SP-A) under this condition.

26 Surfactant protein A (SP-A), a C-type lectin, plays an i

27 Surfactant protein A (SP-A), a major component of lung s

28 Pulmonary surfactant protein A (SP-A), a member of the collectin f

29 The lung collectin, surfactant protein A (SP-A), has emerged as an important

30 We observed that surfactant protein A (SP-A)-deficient mice have impaired

31 al cells (AEC) in the presence or absence of surfactant protein A (SP-A).

32 stance to antibacterial effects of pulmonary surfactant protein A (SP-A).

33 Surfactant protein A (SPA), a lung-specific collectin, s

34 CARDS TX binds to human surfactant protein A and annexin A2 on airway epithelial

35 on of vascular endothelial growth factor and surfactant protein A and B, but this effect was countera

36 es even though several rare proteinopathies, surfactant protein A and C deficiencies, cause severe pu

37 e role in production of parturition signals, surfactant protein A and platelet-activating factor, by

38 eolar wall thickness, cell infiltration, and surfactant protein A concentration in bronchoalveolar la

39 2 +/- 2 n/field; p < 0.0001), and normalized surfactant protein A concentration was higher with flow-

40 Subsequently, surfactant lipids and/or surfactant protein A enhance CD36 transcript and protein

41 Although surfactant protein A, B, and C content and surfactant pr

42 B. dermatitidis without or with normal BALF, surfactant protein A-deficient (SP-A-/-) or surfactant p

43 following exposure to surfactant lipids and surfactant protein A.

44 The pulmonary collectins--surfactant proteins A (SP-A) and D (SP-D)--play importan

45 crobial actions of the pulmonary collectins, surfactant proteins A (SP-A) and D (SP-D).

46 ein (endothelial permeability) and preserved surfactant proteins A and B concentrations as compared w

47 Surfactant proteins A and D (SP-A and -D) play a role in

48 hosphatidylcholine expanded 54-fold, and the surfactant proteins A, B, and C expanded 144-, 4-, and 1

49 itative lipidomic analysis of lipids and the surfactant proteins A, B, and C in lavage fluids from pa

50 uding lamellar body formation, expression of surfactant proteins A, B, and C, alpha-1-antitrypsin, an

51 ctivators 1 and 2 (SRC-1 and SRC-2) regulate surfactant protein-A (SP-A) and platelet-activating fact

52 Previous reports demonstrate that surfactant protein-A (SP-A) binds live M. pneumoniae and

53 Surfactant protein-A (SP-A) is an important antimicrobia

54 Surfactant protein-A (SP-A) is an important mediator of

55 One component of this defense mechanism, surfactant protein-A (SP-A), exerts multifunctional role

56 eptor (VDR); soluble C-type lectins, such as surfactant protein-A (SP-A), SP-D, and mannose-binding l

57 Surfactant protein-A (SP-A), which is secreted by fetal

58 mniotic fluid (AF) macrophages, activated by surfactant protein-A (SP-A).

59 member of this protein family in particular, surfactant protein-A (SP-A).

60 Enrichment of surfactant protein-A in the lung and surfactant of the m

61 , plasminogen activator inhibitor-1 (PAI-1), surfactant protein-A, surfactant protein-D, and intracel

62 e collagen-like domain distinguish the human surfactant protein A1 (SP-A1) variants from the SP-A2 va

63 e gene, SFTPA2, within the interval encoding surfactant protein A2 (SP-A2).

64 heterozygous mutations in the gene encoding surfactant protein A2 (SP-A2, SFTPA2) are associated wit

65 analyze all common and rare variants of the surfactant protein A2, SP-A2, in both A549 cells and in

66 Human surfactant protein-A2 (hSP-A2) is a component of pulmona

67 gs exhibited induction of genes that express surfactant proteins, ABCA3, GM-CSF, podoplanin, and cave

68 Our findings support a model in which the surfactant proteins accelerate adsorption by producing a

69 To determine if hydrophobic surfactant proteins affect the stability of pulmonary su

70 vided insight into the mechanisms underlying surfactant protein and alveolar homeostasis.

71 Pulmonary surfactant proteins and lipids are required for lung fun

72 iAEC2 cells expressed native AEC2 markers (surfactant proteins and LPCAT-1) and contained lamellar

73 miR-200 antagonists inhibited TTF-1 and surfactant proteins and up-regulated TGF-beta2 and ZEB1

74 The formation of surfactant-protein and surfactant-protein-organic anion

75 Gas microbubbles stabilized with lipids, surfactants, proteins and/or polymers are widely used cl

76 FN)-mediated inflammatory responses, loss of surfactant proteins, and apoptosis.

77 ndogenous TTF-1, blocked cAMP stimulation of surfactant proteins, and inhibited miR-200 expression, w

78 Mutations in the genes encoding the lung surfactant proteins are found in patients with interstit

79 The lung surfactant proteins are recognized as critical not only

80 Missense mutations of surfactant proteins are recognized as important causes o

81 Preliminary studies have identified pro-surfactant protein B (pro-SFTPB) to be a promising blood

82 e aliquot was used to quantify levels of pro-surfactant protein B (pro-SFTPB), a previously establish

83 Surfactant protein B (SFTPB) deficiency is a fatal disea

84 Surfactant protein B (Sftpb) is a developmentally regula

85 rowth factor-beta binding protein-4 (LTBP4), surfactant protein B (SFTPB), and transforming growth fa

86 Surfactant protein B (SP-B) deficiency is an autosomal r

87 ification of structural changes of pulmonary surfactant protein B (SP-B) due to the heterogeneous rea

88 Pulmonary surfactant protein B (SP-B) is an essential protein for

89 Surfactant protein B (SP-B) is essential to the function

90 Surfactant protein B (SP-B) is one of two helical, amphi

91 Surfactant protein B (SP-B) proprotein contains three sa

92 from patients with ESRD (ESRD-HDL) included surfactant protein B (SP-B), apolipoprotein C-II, serum

93 tively charged to hydrophobic amino acids in surfactant protein B (SP-B), on the structure and collap

94 B biogenesis remains mysterious but requires surfactant protein B (SP-B), which is synthesized as a p

95 nduced transcriptional activity of the mouse surfactant protein B and A (Sftpb and Sftpa) promoters i

96 Genetic variations in the gene coding for surfactant protein B are associated with more severe lun

97 n 4 of the surfactant protein B gene and the surfactant protein B gene +1580 polymorphism.

98 andem repeat polymorphism in intron 4 of the surfactant protein B gene and the surfactant protein B g

99 is study, the variable nuclear tandem repeat surfactant protein B gene polymorphism in intron 4 is as

100 e presence of variable nuclear tandem repeat surfactant protein B gene polymorphism was associated wi

101 For the variable nuclear tandem repeat surfactant protein B gene polymorphism, patients were fo

102 m-tag single nucleotide polymorphisms in the surfactant protein B gene.

103 and nanoparticle, chain tilt angle, and the surfactant protein B peptide helix tilt angle.

104 ct with TTF-1 and regulate the expression of surfactant protein B, a protein required for lung functi

105 21-residue functional peptide mimic of lung surfactant protein B, an essential protein for lowering

106 SP-B1-25 is a shorter version of lung-surfactant protein B, an important component of lung sur

107 rfactant protein C, 95% for mucin-1, 93% for surfactant protein B, and 89% for the epithelial marker

108 recursor, pigment epithelium-derived factor, surfactant protein B, and serum amyloid A.

109 ptide employed as a functional mimic of lung surfactant protein B, which successfully lowers surface

110 were reduced, with the exception of that for surfactant protein B, which was elevated.

111 ide consisting of the first 25 residues from surfactant protein B.

112 ng at cellular sites consistent with that of surfactant protein B.

113 type II cell differentiation, as measured by surfactant protein B/C mRNA and protein levels.

114 hown promise as functional analogues of lung surfactant proteins B and C (SP-B and SP-C), two helical

115 Surfactant proteins B and C and saturated phosphatidylch

116 ara cells, Clara cell secretory protein, and surfactant proteins B and C, without affecting airway ci

117 P-2 enhanced the activity of the promoter of surfactant protein-B (Sftpb gene) but not other surfacta

118 nd use the method to measure the turnover of surfactant protein-B (SP-B).

119 ary acute lung injury, CPAP-30 yielded lower surfactant protein-B and higher type III procollagen exp

120 GF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells.

121 h surfactant protein A, B, and C content and surfactant protein-B mRNA expression in Stat3(DeltaDelta

122 3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development la

123 II alveolar epithelial cells were capable of surfactant protein-B uptake and stimulated surfactant re

124 eceptor for advanced glycation end products, surfactant protein-B, type III procollagen, and pro-casp

125 nts revealed a specific staining pattern for surfactant protein-B, which was the same pattern observe

126 ) conditional expression of a mutant form of surfactant protein C (L188Q SFTPC) found in familial int

127 We used the mouse surfactant protein C (Sftpc) promoter to over-express th

128 Expression of mutant surfactant protein C (SFTPC) results in endoplasmic reti

129 wild-type (SFTPC+/+) controls, mice lacking surfactant protein C (SFTPC-/-) had greater lung neutrop

130 Biosynthesis of surfactant protein C (SP-C) by alveolar type 2 cells req

131 Surfactant protein C (SP-C) has been suggested to be an

132 To determine the role of surfactant protein C (SP-C) in host defense, SP-C-defici

133 Surfactant protein C (SP-C) is a hydrophobic 35-amino ac

134 Surfactant protein C (SP-C) is a hydrophobic lipopeptide

135 Surfactant protein C (SP-C) is a novel amyloid protein f

136 R) retention, and degradation of the encoded surfactant protein C (SP-C) proprotein.

137 t cause misfolding of the encoded proprotein surfactant protein C (SP-C) trigger endoplasmic reticulu

138 Mice lacking the lung-specific protein surfactant protein C (Sp-C) were lethally irradiated, tr

139 Expression of surfactant protein C (SP-C), which is restricted to alve

140 conditionally target K-RasG12D expression in Surfactant Protein C (SPC)(+) alveolar type 2 cells and

141 , NKX2.1 protein, and its downstream target, surfactant protein C (SpC).

142 In LUAD cells derived from surfactant protein C expressing progenitors, we identify

143 Inhibition of SCD reduced surfactant protein C expression and suppressed rhinoviru

144 Recent reports have linked mutations in the surfactant protein C gene (SFTPC) to familial forms of p

145 h a peptide model for collagen and pulmonary surfactant protein C have been simulated very closely by

146 liferative disease, including lung fibrosis (surfactant protein C precursor; pro-SP-C) and familial d

147 that express a lung-specific TSLP transgene (surfactant protein C promoter (SPC)-TSLP) develop a spon

148 xpressing PPARgamma under the control of the surfactant protein C promoter had reduced expression of

149 human DPP4 (hDPP4) under the control of the surfactant protein C promoter or cytokeratin 18 promoter

150 Transgenic mice using the human Surfactant Protein C promoter to drive the expression of

151 leting the integrin from E10.5 onwards using surfactant protein C promoter-driven Cre.

152 The BRICHOS domain from lung surfactant protein C proprotein (proSP-C) is required fo

153 nd that up to 97% of cells were positive for surfactant protein C, 95% for mucin-1, 93% for surfactan

154 helial markers (Clara cell-specific protein, surfactant protein C, and aquaporin-5), and lack of surf

155 dicated by an increase in the AEC II marker, surfactant protein C, and decreases in the AEC I markers

156 also contained some cells that expressed pro-surfactant protein C, classically described to be expres

157 Mutations in the genes encoding surfactant protein C, SFTPC, and a member of the adenosi

158 We then used a Surfactant protein C-CreER(T2) knock-in allele to follow

159 We show that surfactant protein C-expressing (SPC-expressing) alveola

160 Lungs of both naive surfactant protein C-MCP mice and influenza-infected WT

161 etic lineage-tracing experiments showed that surfactant protein C-positive (SFTPC-positive) AEC2s sel

162 ced isolectin B4(+) alveolar capillaries and surfactant protein C-positive alveolar epithelial type-I

163 Mutations in the gene encoding SP-C (surfactant protein C; SFTPC) have been linked to interst

164 I73T) in the alveolar type 2 cell-restricted surfactant protein-C (SP-C) gene (SFTPC) has been linked

165 ected against the ATII cell-specific antigen surfactant protein-C (SP-C) then administered to C57BL/6

166 Either deletion of TLR4 or HA synthase 2 in surfactant-protein-C-positive AEC2s leads to impaired re

167 rovide the most direct evidence yet that the surfactant proteins can induce negative curvature in lip

168 Our findings show that surfactant proteins can promote negative curvature, and

169 tion analysis showed that baseline values of surfactant protein D (46.6 ng/mL vs 34.6 ng/mL, p=0.0018

170 + carbohydrate recognition domains of human surfactant protein D (NCRD) with CL-43 (RCL-43-NCRD) and

171 RATIONALE: Recombinant fragment of human surfactant protein D (rfhSP-D) has been shown to suppres

172 Mice deficient in surfactant protein D (Sftpd) develop progressive age-rel

173 Surfactant protein D (SP-D) and CD14 are important innat

174 or the lung extracellular matrix components surfactant protein D (SP-D) and mucin 5b (Muc5b).

175 Circulating levels of the biomarkers surfactant protein D (SP-D) and soluble receptor for adv

176 collectins mannose-binding lectin (MBL) and surfactant protein D (SP-D) are regulated by tissue fibr

177 ins such as mannose-binding lectin (MBL) and surfactant protein D (SP-D) become temporarily deposited

178 Lung surfactant protein D (SP-D) binds to Mycobacterium tuber

179 The innate host defense component surfactant protein D (SP-D) interacts with glycans on th

180 Surfactant protein D (SP-D) is a member of the collectin

181 Surfactant protein D (SP-D) is an important effector of

182 Surfactant protein D (SP-D) is an important regulator of

183 Surfactant protein D (SP-D) is an innate immune effector

184 Surfactant Protein D (SP-D) is an oligomerized C-type le

185 Surfactant protein D (SP-D) is critical for maintenance

186 he recognition of influenza A virus (IAV) by surfactant protein D (SP-D) is mediated by interactions

187 Our previous studies showed that surfactant protein D (SP-D) is present in human tear flu

188 Innate immune molecule surfactant protein D (SP-D) plays a critical role in hos

189 Surfactant protein D (SP-D) plays diverse and important

190 Surfactant protein D (SP-D) plays important roles in ant

191 Surfactant protein D (SP-D) plays important roles in inn

192 Surfactant protein D (SP-D) plays important roles in lun

193 Surfactant protein D (SP-D) plays important roles in the

194 previous studies documenting that pulmonary surfactant protein D (SP-D) protects C. neoformans cells

195 recognition domains (CRDs) of lung collectin surfactant protein D (SP-D) recognize sugar patterns on

196 Surfactant protein D (SP-D) shows specific interactions

197 t-associated surfactant protein A (SP-A) and surfactant protein D (SP-D) to Mtb.

198 Surfactant protein D (SP-D), a component of innate immun

199 Lung surfactant protein D (SP-D), a key factor in first-line

200 Pulmonary surfactant protein D (SP-D), a member of the collectin f

201 Polymorphisms of surfactant protein D (SP-D), an important molecule withi

202 ins, Clara cell secretory protein (CC16) and surfactant protein D (SP-D), and five systemic inflammat

203 The roles of NK cells, surfactant protein D (SP-D), and IFN-gamma, as well as t

204 emonstrated direct interactions of HNPs with surfactant protein D (SP-D), another important effector

205 Surfactant protein D (SP-D), shown to play a role in hos

206 The role of surfactant protein D (SP-D), which inhibits P. aeruginos

207 Surfactant protein D (SP-D)-deficient (SP-D-/-) mice exh

208 t on virulence in naive BALB/c, C57BL/6, and surfactant protein D (SP-D)-deficient mice.

209 a) production and the enhanced expression of surfactant protein D (SP-D).

210 es can be removed from the lung by pulmonary surfactant protein D (SP-D).

211 Surfactant protein D (SPD) plays an important role in su

212 d, a tripartite fusion protein was made from surfactant protein D (SPD), HIV-1 Gag as a test antigen,

213 olar lavage and various serum markers (e.g., surfactant protein D and KL-6) each may provide useful i

214 soluble multitrimers of BAFF and APRIL using surfactant protein D as a scaffold, and we vaccinated mi

215 in, which evolved through duplication of the surfactant protein D gene in ruminants, prefers mannose

216 nt of peritoneal Mos with the lung collectin surfactant protein D inhibited AC uptake, and fluticason

217 Surfactant protein D is a pattern recognition molecule t

218 re generally not inhibited by the collectins surfactant protein D or mannose binding lectin because o

219 Surfactant protein D preferentially binds to glucose and

220 nary and activation-regulated chemokine, and surfactant protein D significantly increased the areas u

221 nary and activation-regulated chemokine, and surfactant protein D significantly strengthens this asso

222 e 2-trimer form, and fusion with the body of surfactant protein D was used to produce the 4-trimer fo

223 matrix metalloproteinase (MMP)-7, MMP-1, and surfactant protein D were assessed by ELISA.

224 ombinant homotrimeric fragment of human lung surfactant protein D with a series of bound ligands have

225 ptor for advanced glycation end products and surfactant protein D) and endothelial injury (angiopoiet

226 multitrimerized using the lung protein SP-D (surfactant protein D), enhancing immune responses.

227 KGF treatment increases BAL surfactant protein D, a marker of type II alveolar epith

228 nterleukin-1ra, tumor necrosis factor alpha, surfactant protein D, and interleukin-10.

229 eceptor for advanced glycation end products, surfactant protein D, angiopoietin-2, interleukin-6, int

230 a levels of fibrinogen, chemokine ligand 18, surfactant protein D, C-reactive protein, Clara cell sec

231 ding of three innate immune lectins, namely, surfactant protein D, human galectin-8, and Siglec-14, t

232 e equivalent Arg-343 in the homologous human surfactant protein D, is sufficiently small to allow con

233 KGF increased BAL concentrations of surfactant protein D, matrix metalloproteinase (MMP)-9,

234 alysis, we identified four serum biomarkers (surfactant protein D, matrix metalloproteinase 7, CA19-9

235 infection, and, when combined with pulmonary surfactant protein D, their antiviral effects were addit

236 surfactant protein A-deficient (SP-A-/-) or surfactant protein D-deficient (SP-D-/-) BALF, or a mixt

237 on molecules in the collectin family, namely surfactant proteins D and A (Sp-D and Sp-A, respectively

238 The innate immune molecule surfactant protein-D (SP-D) plays an important regulator

239 After challenge with high-dose surfactant protein-D (SP-D)-sensitive influenza A/Philad

240 production, and proteolysis of the collectin surfactant protein-D (SP-D).

241 In a subset, we compared plasma levels of surfactant protein-D and von Willebrand factor antigen b

242 ct of leukoreduced blood on plasma levels of surfactant protein-D or von Willebrand factor antigen wa

243 oluble tumor necrosis factor receptor-1, and surfactant protein-D) had nearly equivalent prognostic v

244 r inhibitor-1 (PAI-1), surfactant protein-A, surfactant protein-D, and intracellular adhesion molecul

245 n molecule-1, von Willebrand factor antigen, surfactant protein-D, and soluble tumor necrosis factor

246 indicate that at 47-53 mN/m, the hydrophobic surfactant proteins destabilize the compressed monolayer

247 l temperatures indicate that the hydrophobic surfactant proteins disrupt the ordered structures that

248 This was accompanied by decreased surfactant protein expression and accumulation of podopl

249 Immunohistochemical analysis of surfactant protein expression in three patients revealed

250 fferentiation and an almost complete loss of surfactant protein expression.

251 h extracellular matrix components, including surfactant proteins, fibronectin, and mucin, which provi

252 Ranaspumin-2 (Rsn-2) is a surfactant protein found in the foam nests of the tungar

253 tspots near VMP1/MIR21 and indel hotspots in surfactant protein genes (SFTPA1, SFTPB, and SFTPC).

254 the proper formation of lamellar bodies and surfactant protein homeostasis.

255 the in vitro surface-active behavior of lung surfactant proteins in a mixed lipid film.

256 Examples include surfactant proteins in lung alveoli, albumin in liver pa

257 viral lesions and impaired the production of surfactant proteins in the alveolar epithelium.

258 also induced the sustained expression of the surfactant proteins in the lungs.

259 al foam formation is facilitated by specific surfactant proteins in the mixture, further stabilized b

260 factant protein-B (Sftpb gene) but not other surfactant proteins in vitro.

261 is a complex mixture of lipids and specific surfactant proteins, including the hydrophobic proteins

262 Other than constitutively expressed surfactant proteins, it is unknown whether alveolar epit

263 Mutations in surfactant proteins lead to pulmonary fibrosis and are a

264 However, surfactant protein levels were reduced, with the excepti

265 Identification of the surfactant proteins, lipid transporters, and transcripti

266 ions between highly glycosylated viruses and surfactant proteins may lead to an improved understandin

267 studies reported here, we tested whether the surfactant proteins might promote adsorption by inducing

268 philic proteins, but neither the hydrophobic surfactant proteins nor the phospholipids, induced agglo

269 Rarely, genetic defects in surfactant proteins or the common beta chain for the GM-

270 The formation of surfactant-protein and surfactant-protein-organic anion deposits is proposed on

271 Numerical density of surfactant protein positive cells was determined by immu

272 tion, decreased angiogenesis, and diminished surfactant protein production and may increase the risk

273 iate, supports the proposed model of how the surfactant proteins promote adsorption.

274 To determine how the hydrophobic surfactant proteins promote insertion of the surfactant

275 luid (LLF), which contains phospholipids and surfactant proteins, represents a first contact site wit

276 ession of lung-specific genes, including the surfactant proteins required for pulmonary function afte

277 is a truncated version of the full pulmonary surfactant protein SP-B, with dipalmitoylphosphatidylcho

278 tributed to SP-C or to the other hydrophobic surfactant protein SP-B.

279 The hydrophobic surfactant proteins SP-B and SP-C greatly accelerate the

280 rtitioning assay to assess the effect of the surfactant proteins SP-B and SP-C on cholesterol distrib

281 The hydrophobic surfactant proteins SP-B and SP-C promote rapid adsorpti

282 (CLSE), which also contains the hydrophobic surfactant proteins SP-B and SP-C.

283 EKO lungs showed increased expression of the surfactant proteins Sp-B, Sp-C, and Sp-D, and displayed

284 Surfactant protein (SP) D is a member of the collectin f

285 hough many studies have shown that pulmonary surfactant protein (SP)-A functions in innate immunity,

286 Pulmonary surfactant protein (SP)-A is an endogenously produced li

287 Here, we study rare and common surfactant protein (SP)-A1 and SP-C variants, either dis

288 for a missense mutation in the gene encoding surfactant protein (SP)-A2 (SFTPA2) contains more TGF-be

289 om the N-terminal saposin-like domain of the surfactant protein (SP)-B proprotein, and SP-A are lung

290 eased amounts of surfactant phospholipid and surfactant protein (SP)-B.

291 ar epithelial cells under the control of the surfactant protein (SP)-C promoter develop pulmonary inf

292 Plasma surfactant protein (SP)-D > 31 ng/ml, matrix metalloprot

293 e alpha-defensins were also shown to bind to surfactant protein (SP)-D and reduce its antiviral activ

294 lso engineered MASP binding into a pulmonary surfactant protein (SP-A), which has the same domain str

295 Pulmonary surfactant proteins (SP-) A and D are innate immune patt

296 differentiation and expression of the major surfactant protein, SP-A, in mid-gestation human fetal l

297 ssion of the gene (SFTPA) encoding the major surfactant protein, SP-A, in midgestation human fetal lu

298 The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate t

299 systemic hypercoagulant state, reduction of surfactant proteins SpC, SpB, and SpA, decline of lung c

300 thetic peptide surrogates) act like alveolar surfactant proteins to rapidly bind and stabilize the te