ライフサイエンスコーパス: surfactant protein B

1 ide consisting of the first 25 residues from surfactant protein B.

2 ng at cellular sites consistent with that of surfactant protein B.

3 solated preparations or to altered levels of surfactant protein B.

4 ct with TTF-1 and regulate the expression of surfactant protein B, a protein required for lung functi

5 21-residue functional peptide mimic of lung surfactant protein B, an essential protein for lowering

6 SP-B1-25 is a shorter version of lung-surfactant protein B, an important component of lung sur

7 nduced transcriptional activity of the mouse surfactant protein B and A (Sftpb and Sftpa) promoters i

8 nment of this fragment with type II-specific surfactant protein B and C promoters shows similar conse

9 lts: We document here extensive SP-B and -C (surfactant protein-B and -C) processing defects in IPF A

10 ary acute lung injury, CPAP-30 yielded lower surfactant protein-B and higher type III procollagen exp

11 hown promise as functional analogues of lung surfactant proteins B and C (SP-B and SP-C), two helical

12 nts were made for PL and DAPL alone; with 3% surfactant proteins B and C (SP-B/C); with SP-B/C and 5%

13 Surfactant proteins B and C and saturated phosphatidylch

14 harbor IgA autoantibodies against pulmonary surfactant proteins B and C and that these autoantibodie

15 ults: IgA autoantibodies targeting pulmonary surfactant proteins B and C were elevated in patients wi

16 factant (BC mixture = PL mixture + synthetic surfactant proteins B and C) at a dose of 100 mg alpha1-

17 ara cells, Clara cell secretory protein, and surfactant proteins B and C, without affecting airway ci

18 regions which could bind to the hydrophobic surfactant proteins B and C.

19 tretch (amphiregulin), damage to epithelial (surfactant protein B) and endothelial cells (vascular ce

20 rfactant protein C, 95% for mucin-1, 93% for surfactant protein B, and 89% for the epithelial marker

21 recursor, pigment epithelium-derived factor, surfactant protein B, and serum amyloid A.

22 Genetic variations in the gene coding for surfactant protein B are associated with more severe lun

23 type II cell differentiation, as measured by surfactant protein B/C mRNA and protein levels.

24 el (4MP) consisting of the precursor form of surfactant protein B, cancer antigen 125, carcinoembryon

25 Lung morphology, surfactant proteins B-D, lung tissue, alveolar phospholi

26 atory adaptation at birth include hereditary surfactant protein B deficiency, mutations in surfactant

27 n 4 of the surfactant protein B gene and the surfactant protein B gene +1580 polymorphism.

28 andem repeat polymorphism in intron 4 of the surfactant protein B gene and the surfactant protein B g

29 These reagents down-regulated surfactant protein B gene expression in respiratory epit

30 is study, the variable nuclear tandem repeat surfactant protein B gene polymorphism in intron 4 is as

31 e presence of variable nuclear tandem repeat surfactant protein B gene polymorphism was associated wi

32 For the variable nuclear tandem repeat surfactant protein B gene polymorphism, patients were fo

33 or inhibited transcriptional activity of the surfactant protein B gene promoter.

34 or-activated receptor gamma was evaluated in surfactant protein B gene regulation.

35 f TTF-1 mediates PKA-dependent activation of surfactant protein B gene transcription.

36 m-tag single nucleotide polymorphisms in the surfactant protein B gene.

37 GF-beta represses transcription of pulmonary surfactant protein-B gene in lung epithelial cells.

38 The studies support the concept that surfactant protein B homeostasis is influenced by neutra

39 s completely abolish expression of the human surfactant protein B (hSP-B) 1.5 kb lacZ reporter gene i

40 Intratracheal treatment with exogenous surfactant protein B improved survival and lung histolog

41 showed no postnatal expansion but had normal surfactant protein B levels.

42 h surfactant protein A, B, and C content and surfactant protein-B mRNA expression in Stat3(DeltaDelta

43 mice was not associated with accumulation of surfactant proteins B or C, or their mRNAs, distinguishi

44 ences in selected proteins, namely pulmonary surfactant protein B, osteopontin, kallikrein 5 and gale

45 weight% and 7:3 or 4:1 DPPC:POPG ratios), a surfactant protein B peptide analog (KL4, Super Mini-B,

46 and nanoparticle, chain tilt angle, and the surfactant protein B peptide helix tilt angle.

47 d of a monolayer of palmitic acid (PA) and a surfactant protein B peptide, SP-B(1-25).

48 Preliminary studies have identified pro-surfactant protein B (pro-SFTPB) to be a promising blood

49 e aliquot was used to quantify levels of pro-surfactant protein B (pro-SFTPB), a previously establish

50 thyroid transcription factor (TTF)-1 and pro-surfactant protein-B (pro-SP-B), and mesenchymal (alpha-

51 3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development la

52 Surfactant protein B (SFTPB) deficiency is a fatal disea

53 Surfactant protein B (Sftpb) is a developmentally regula

54 rowth factor-beta binding protein-4 (LTBP4), surfactant protein B (SFTPB), and transforming growth fa

55 P-2 enhanced the activity of the promoter of surfactant protein-B (Sftpb gene) but not other surfacta

56 and depth of each residue of lung pulmonary surfactant protein B (SP-B(1-25)) in a phospholipid bila

57 Inability to produce surfactant protein B (SP-B) causes fatal neonatal respir

58 Surfactant protein B (SP-B) deficiency is a rare genetic

59 Surfactant protein B (SP-B) deficiency is an autosomal r

60 ification of structural changes of pulmonary surfactant protein B (SP-B) due to the heterogeneous rea

61 ociated with increased apoptosis and reduced surfactant protein B (SP-B) expression.

62 The rate of loss of surfactant protein B (SP-B) from these preterm animals'

63 ted the -500 to +41 promoter activity of the surfactant protein B (SP-B) gene in respiratory epitheli

64 ming growth factor-beta (TGF-beta) represses surfactant protein B (Sp-B) gene transcription through a

65 Surfactant protein B (SP-B) is a 79-amino acid peptide c

66 Surfactant protein B (SP-B) is a 79-residue essential co

67 Surfactant protein B (SP-B) is a hydrophobic, 79 amino a

68 Surfactant protein B (SP-B) is a small, hydrophobic prot

69 Pulmonary surfactant protein B (SP-B) is an essential protein for

70 Surfactant protein B (SP-B) is detected in the airways a

71 Surfactant protein B (SP-B) is essential for maintenance

72 The lung-specific surfactant protein B (SP-B) is essential for surfactant

73 Surfactant protein B (SP-B) is essential to the function

74 Surfactant protein B (SP-B) is essential to the function

75 Surfactant protein B (SP-B) is one of two helical, amphi

76 Surfactant protein B (SP-B) is required for the maintena

77 Surfactant protein B (SP-B) is secreted into the airspac

78 Human surfactant protein B (SP-B) is synthesized by type II ce

79 Surfactant protein B (SP-B) mRNA and protein are restric

80 Surfactant protein B (SP-B) proprotein contains three sa

81 the 102-amino acid C-terminal propeptide of surfactant protein B (SP-B) was analyzed by characterizi

82 Surfactant protein B (SP-B), a hydrophobic protein of lu

83 from patients with ESRD (ESRD-HDL) included surfactant protein B (SP-B), apolipoprotein C-II, serum

84 tively charged to hydrophobic amino acids in surfactant protein B (SP-B), on the structure and collap

85 B biogenesis remains mysterious but requires surfactant protein B (SP-B), which is synthesized as a p

86 esized to resemble the amino acid pattern of surfactant protein B (SP-B).

87 imulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphat

88 ith abnormal surfactant function and reduced surfactant protein-B (SP-B) expression.

89 Inherited deficiency of surfactant protein-B (SP-B) is a fatal autosomal recessi

90 nd use the method to measure the turnover of surfactant protein-B (SP-B).

91 Full length surfactant protein-B (SP-B1-78) (B) and palmitoylated su

92 the E4 promoter replaced by the promoter for surfactant protein B (SPB).

93 mal patterns and numbers of cells expressing surfactant protein-B suggest that differentiation of typ

94 ation, as indicated by lack of expression of surfactant protein B, surfactant protein C, the Clara ce

95 eceptor for advanced glycation end products, surfactant protein-B, type III procollagen, and pro-casp

96 II alveolar epithelial cells were capable of surfactant protein-B uptake and stimulated surfactant re

97 Surfactant protein B was similar in the diagnostic group

98 ptide employed as a functional mimic of lung surfactant protein B, which successfully lowers surface

99 were reduced, with the exception of that for surfactant protein B, which was elevated.

100 in significant part, dependent on pulmonary Surfactant Protein-B, which plays an unanticipated role

101 nts revealed a specific staining pattern for surfactant protein-B, which was the same pattern observe