ライフサイエンスコーパス: surrogate

1 ophenone imine, a readily accessible ammonia surrogate.

2 trium-86 isotope can be used as a gadolinium surrogate.

3 catalytic cycle while serving as an ammonia surrogate.

4 -azaproline derivatives as potential proline surrogates.

5 alogs, were evaluated as potential sparteine surrogates.

6 ist) or bacterial (ODN 2395, a TLR9 agonist) surrogates.

7 aturated cyclohexanones as aryl electrophile surrogates.

8 M) using mass-based measurements as exposure surrogates.

9 ut with many variables improperly treated as surrogates.

10 C) by evaluating the matching gamma-emitting surrogate, (203)Pb.

11 essments and diligent searches for potential surrogates; 3) institutions should manage decision-makin

12 Such proteoforms (using synthetic peptide surrogates) act like alveolar surfactant proteins to rap

13 isceral adipose tissue (VAT), and identified surrogate agonist peptides, with differing affinities an

14 nin signaling in response to Wnt3a versus a 'surrogate agonist' that cross-links Fzd to LRP6, reveale

15 onoclonal antibodies, previously shown to be surrogate agonists for mutant INSR, were then tested by

16 AT-Treg cells expanded in vivo by one of the surrogate agonists preserved the typical VAT-Treg transc

17 4 bioanalytical assays detecting 6 different surrogate analyte classes representing at least 14 uniqu

18 g infection, we utilized vaccinia virus as a surrogate and showed that a vaccinia virus expressing MC

19 with higher levels of inosine, an adenosine surrogate, and of cyclic adenosine monophosphate.

20 a murine pathogen extensively employed as a surrogate animal model for EHEC.

21 In a surrogate assay, colony organizations are profiled by tr

22 and may be substituted for a smaller set of surrogate assays.

23 K (1), a surrogate biomarker for (18)F-FGln intracellular transpo

24 k (3), a surrogate biomarker for glutaminolysis rate, was relativ

25 ifications of hemoglobin have been used as a surrogate biomarker for monitoring the oxidative stress

26 We focus on age prediction as a surrogate biomarker in 674 subjects from the Cam-CAN dat

27 6 system, can provide a non-invasive imaging surrogate biomarker of tissue oxygenation status.

28 area under the curve [AUC] = 0.83); however, surrogate biomarkers had moderate performance in disting

29 plementation on serum cholesterol profile or surrogate biomarkers of cholesterol absorption and endog

30 ation for 24 wk had no significant effect on surrogate biomarkers of cholesterol absorption or endoge

31 nterventions in I/R, suggesting their use as surrogate biomarkers of endothelial integrity.

32 e of nitric oxide as a spin probe and oxygen surrogate, both the small molecule and the peptide subst

33 ical innovations, such as genome editing and surrogate broodstock technologies, may further expedite

34 e saturation index (cTSI, cerebral perfusion surrogate), calf circumference (CC, central hypovolaemia

35 emonstrates that the use of unrepresentative surrogates can lead to substantial systematic errors in

36 The diagnosis of CS usually requires surrogate cardiac imaging biomarkers, as endomyocardial

37 Using ENCODE ChIP-seq data of surrogate cell lines and motif analysis we observed that

38 s, features that cannot be captured by using surrogate cell lines or animal models.

39 terol-lowering medications (n = 114), plasma surrogate cholesterol absorption and endogenous synthesi

40 lements; three elements focused on caregiver-surrogate communication (admission meeting, follow-up me

41 Rs of pMHCII-specific CD4(+) T cells, and 2) surrogate coreceptor modules enhance the function of the

42 to the commercially available sulfur dioxide surrogate, DABSO, generates a metal sulfinate which is r

43 Using statistical testing with seizure surrogate data and a unique dataset of continuously reco

44 s to independently consent, and implementing surrogate decision making.

45 plicable advance directive, and an available surrogate decision-maker.

46 ltidisciplinary care, and communication with surrogate decision-makers.

47 Measurements of cardiac output (or its surrogates) during passive leg raising are, thus, mandat

48 Plaque inflammation is often used as a surrogate end point for plaque vulnerability in animals.

49 development, the CS activity was chosen as a surrogate end point to conservatively assess hemostatic

50 randomization and after 2 weeks, as primary surrogate end points of efficacy and safety, respectivel

51 f COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) study.ResultsA total of 7

52 kidney disease (DKD) conventionally define a surrogate endpoint either as a percentage of decrease of

53 from cerebrospinal fluid (CSF) is used as a surrogate endpoint for all-cause mortality.

54 These results support the use of HVPG as a surrogate endpoint for interventions that lower portal p

55 ted significantly with VA and may serve as a surrogate endpoint in clinical trials.

56 evidence of the potential value of nGA as a surrogate endpoint in future intervention trials for the

57 ccelerated regulatory approval, but EFA as a surrogate endpoint requires further validation.

58 s upon existing studies to validate EFA as a surrogate endpoint.

59 A threshold may be considered a target for a surrogate endpoint.

60 ime to viral rebound is frequently used as a surrogate endpoint.

61 ood and Drug Administration allows for using surrogate endpoints for accelerated regulatory approval,

62 surements of the pace of aging are needed as surrogate endpoints in trials of therapies designed to p

63 Across all studies, surrogate endpoints predominated as outcomes, followed b

64 ovide a comprehensive review of clinical and surrogate endpoints used in trials for non-metastatic re

65 f COPD Longitudinally to Identify Predictive Surrogate Endpoints) data.

66 f COPD Longitudinally to Identify Predictive Surrogate Endpoints) study.Measurements and Main Results

67 tablished correlates of clinical efficacy or surrogate endpoints, they remain critical to the overall

68 Using a combination of surrogate entry assays and live virus, we demonstrate th

69 Immunization with this surrogate, especially when coupled with blockade of TNFa

70 Our self-made surrogate eye model aims to address this void in our jun

71 Our surrogate eye model is low-cost, quick and easy to repro

72 the PET data and validated (86)Y-NM600 as a surrogate for (177)Lu-NM600.

73 work was to explore (132)La as a PET imaging surrogate for (225)Ac using a DOTA-based, tumor-targetin

74 binding and Fc gamma receptor activation, a surrogate for ADCC function.

75 f the 4 quantitative metrics with LVMI, as a surrogate for amyloid burden.

76 ed by a common spermicide (Nonoxynol-9, as a surrogate for any mechanism of cervical epithelial damag

77 tive of executive control abilities, and our surrogate for attentional reserves.

78 sine levels in plasma during withdrawal as a surrogate for brain adenosine, which plays a role in fin

79 calculate the autoregulation index (ARI, as surrogate for CA).

80 AT is an independent parameter rather than a surrogate for cardiovascular risk.

81 d use it to model uptake from cosmetics as a surrogate for condensed environmental media.

82 la and flagship species, and a comprehensive surrogate for conservation of freshwater biodiversity.

83 adenomas would develop advanced adenomas, a surrogate for CRC.

84 et concentration, the hybridization current (surrogate for detection sensitivity) increases with the

85 To validate entropy as a surrogate for differentiated state functionally, we iden

86 hi6 bacteriophages, the latter a recommended surrogate for EBOV.

87 lusion: (18)F-FAC PET was shown to be a good surrogate for gemcitabine uptake and, when combined with

88 iate the potential limitations of 2-FDG as a surrogate for glucose metabolic rate and the potential r

89 having a flush toilet in the home (likely a surrogate for higher socioeconomic status).

90 fibroblast growth factor (FGF) 19 levels (a surrogate for intestinal farnesoid X receptor [FXR] acti

91 regulate key cellular processes, serve as a surrogate for intracellular pH conditions, and provide a

92 howed reduced levels of the AP4E1 subunit, a surrogate for levels of the AP-4 complex.

93 rnal fluorescent reference to measure qAF as surrogate for lipofuscin accumulation.

94 esis that unloading (recovery) may be a good surrogate for loading.

95 egative (FN) screening examinations can be a surrogate for long-term outcomes, such as breast cancer

96 T among active tuberculosis (TB) patients (a surrogate for LTBI patients), high-risk populations, and

97 to test whether larval size can be used as a surrogate for migration potential arising from larval lo

98 We thus advise not using larval size as a surrogate for migration potential in distribution models

99 HBGA-blocking antibodies are a surrogate for neutralization in human noroviruses.

100 strong hemagglutination inhibition titers, a surrogate for neutralization of intestinal adhesion medi

101 EFS is a weak surrogate for OS and is not suitable for use as an inter

102 wn that metastasis-free survival is a strong surrogate for overall survival (OS) in men with intermed

103 Particle gross beta activity was used as a surrogate for particle radioactivity and was measured fr

104 Salivary oxytocin is a weak surrogate for plasmatic oxytocin.

105 cess to care, cost may not be an appropriate surrogate for predicting clinical risk among vulnerable

106 e that GFR, even when estimated, is a useful surrogate for predicting secretory drug clearances in su

107 e human serum bactericidal assay, which is a surrogate for protection.

108 edict life-threatening VA (LTVA) as a closer surrogate for SCD.

109 ement, electrical stimulation or a tap, as a surrogate for sedation and general anesthesia, respectiv

110 Increased rest fragmentation, a potential surrogate for sleep fragmentation, is independently asso

111 Educational attainment is widely used as a surrogate for socioeconomic status (SES).

112 -hour urinary MeS and BeS were measured as a surrogate for systemic bioavailability.

113 eristics of crying and monitoring a reliable surrogate for systolic blood pressure.

114 LG-1 is also disrupted by heparin, used as a surrogate for the extracellular matrix component, hepara

115 f techniques have been introduced in which a surrogate for the intractable density is learned, includ

116 zaphospholium triflate salt serves well as a surrogate for the introduction of the cationic 2-(1,2'-b

117 ce-based ToL can be an empirically derivable surrogate for the organism ToL.

118 onceptual framework that imaging is a robust surrogate for therapeutic efficacy.

119 ollect and quantify, sex can serve as a good surrogate for these factors.

120 onitor clonality and evolving mutations as a surrogate for tumour biopsy.

121 pears to represent an appropriate adenovirus surrogate for UV system performance evaluation and illus

122 ia chlorella virus (PBCV-1) as an adenovirus surrogate for validation of UV reactors was evaluated.

123 N-methyliminodiacetic acid) as an in situ CO surrogate for various palladium-catalyzed transformation

124 ti-RBD or anti-ECD IgG titers can serve as a surrogate for VN titers to identify suitable plasma dono

125 There is a need to identify nonpathogenic surrogates for adenovirus for the water treatment indust

126 L) and C(P), (2) accuracy when using C(P) as surrogates for C(L), (3) effects of experimental variabl

127 sing interest as unique targeting vectors or surrogates for endogenous biomolecules.

128 stigates the use of neoglycolipids (NGLs) as surrogates for GSLs for catch-and-release-electrospray i

129 ty of two different bacterial orthologues as surrogates for human OGA.

130 enic, easy to culture, and readily available surrogates for human pathogens.

131 al perfusion are often monitored as clinical surrogates for improvement in cardiac output.

132 or experiments and at the same time provide surrogates for improving the subsequent analysis.

133 king of others to emulate the use of captive surrogates for model training.

134 BCPs) are important motifs in drug design as surrogates for p-substituted arenes and alkynes.

135 nd Bacillus anthracis (B. anthracis) Sterne, surrogates for potential bacterial bioterrorism agents,

136 ssia by the measures traditionally viewed as surrogates for successful immunization.

137 ility that measurement of mtDNA damage is a "surrogate" for LRRK2 kinase activity and consequently of

138 Physicians, nurses, patients, and surrogates generated a consensus-based framework to guid

139 l properties of the macrocycle with a linear surrogate have revealed significant effects of the struc

140 gs indicate that CSF sTREM2 could serve as a surrogate immune biomarker of neuronal injury in Parkins

141 herichia coli and Citrobacter rodentium, its surrogate in a mouse infection model, sense galacturonic

142 fore NIR-based GA assessment may be a useful surrogate in clinical settings.

143 p of TAPBPR functions as an internal peptide surrogate in peptide-depleted environments stabilizing e

144 are limited by the scarcity of EE cells (or surrogates) in both in vivo and in vitro systems.

145 anal squamous cell carcinoma (SCC), and its surrogates, in SOTR.

146 extended biological half-life of the GB1107 surrogate indicated that systemic administration is poss

147 reas the fast excretion profile of the TD139 surrogate indicated that systemic application of disacch

148 ion tests with SARS-CoV-2, and 15 tests with surrogates, indicated sunlight, ultraviolet light, ethan

149 e country where the case was reported, and a surrogate indicator of the historical strength of the co

150 night-time light data is first proposed as a surrogate indicator to mine and forecast the average hou

151 e metabolism have been limited by the use of surrogate insulin sensitivity indices, small sample size

152 The utility of these cyclopropanone surrogates is demonstrated in a mild and stereospecific

153 g of the VRC26UCA heavy chain with the mouse surrogate light chain may contribute to this phenotype.

154 ormation of reactive oxygen species (ROS) in surrogate lung fluid containing antioxidants.

155 he fatty liver index (FLI) is a non-invasive surrogate marker and predictor of NAFLD.

156 interval that QT prolongation is an accepted surrogate marker for arrhythmia.

157 IgE reactivity to PHMB as surrogate marker for biguanide/hexamethylene reactivity

158 1 collagen-targeted gadolinium-based probe (surrogate marker for extracellular matrix (ECM) remodeli

159 SARS-CoV-2 culture may be used as a surrogate marker for infectivity and inform de-isolation

160 ) remodeling) and an iron oxide-based probe (surrogate marker for inflammatory activity), in one imag

161 kers led to tumor mutational burden (TMB) as surrogate marker for neoantigens presented.

162 study aimed to evaluate vWF-Ag as an adjunct surrogate marker for risk stratification on the waiting

163 guidelines recommend trough monitoring as a surrogate marker for the target area under the curve ove

164 status of the optic nerve and will provide a surrogate marker in future remyelination clinical trials

165 -2, highlighting the potential of VLA-4 as a surrogate marker of acute lung inflammation.

166 rophy on serial MRI are frequently used as a surrogate marker of disease progression in Alzheimer's d

167 CD30 may be a surrogate marker of early replication or viral transcrip

168 P16 overexpression, a surrogate marker of HPV association, was a strong predic

169 Allergen-specific IgG, which served as a surrogate marker of maintaining protective IgG responses

170 P-43-related disease, and which is used as a surrogate marker of non-amyloid-beta protein aggregation

171 om arterial plasma to tissues) was used as a surrogate marker of perfusion to correct the binding pot

172 HCMV IgG level, a surrogate marker of viral activity, was correlated with

173 Using CD103 as a surrogate marker to identify cells that have undergone T

174 ver-operating-characteristic curves for each surrogate marker were created and tested against each ot

175 des and may eventually be considered as a T2 surrogate marker.

176 Surrogate markers (eg, resistive index) fail to quantify

177 iomarkers and determine their suitability as surrogate markers for interventional trials.

178 research and the use of network measures as surrogate markers in research setting.

179 The use of robust surrogate markers may accelerate early-phase drug develo

180 Studies examining surrogate markers of genetic susceptibility to AF, such

181 tion led by renal dietitians did not improve surrogate markers of glucose metabolism.

182 artially independent of insulin resistance), surrogate markers of oxidative stress and gut microbial

183 to women of all ancestries; 2) intermediate surrogate markers of response to preventive measures; 3)

184 ages, allowing potential definition of novel surrogate markers.

185 odel and compare its performance to existing surrogate markers.

186 ed through external calibration, often using surrogate matrices, which has inherent limitations for t

187 1% for immuno-MALDI), without the need for a surrogate matrix or additional patient material for cali

188 medication level variability index (MLVI), a surrogate measure of adherence to immunosuppression in p

189 y detected malaria pigment provided the best surrogate measure of adverse birth outcomes in a high-tr

190 f MRI-assessed rectal cancer perfusion, as a surrogate measure of hypoxia, for local treatment respon

191 d socioeconomic deprivation and an objective surrogate measure of medication adherence in children po

192 The CBB panel response acts as a surrogate measurement for the performance of nitrificati

193 l programs have been added and as the use of surrogate measures has been encouraged.

194 after adjusting for patient characteristics, surrogate measures of disease severity, and clustering o

195 dentify disease features that can be used as surrogate measures of efficacy in clinical trials.

196 g two tumor models, an algorithm to retrieve surrogate measures of hypoxia levels from the images was

197 Surrogate measures of infectious exposures have been con

198 ovements in ejection fraction (P = 0.08) and surrogate measures of left ventricle compliance did not

199 has increasingly accepted less data and more surrogate measures, and has shortened its review times.

200 ion of agonist and the purified G(s) protein surrogate mini-G(s) (mG(s)) yielded a mobility-shifted a

201 from Rattus norvegicus (RHV) is a promising surrogate model due to its recapitulation of HCV-like ch

202 The rates of this surrogate model encode both the structure of the underly

203 iratory ectromelia virus (ECTV) infection, a surrogate model for smallpox.

204 nst lethal infection in a Sendai virus mouse surrogate model of human HPIV3 disease when administered

205 .7 macrophages with Mycobacterium marinum, a surrogate model organism for M. tuberculosis, and found

206 Here, we build a Machine Learning (ML) surrogate model that captures adsorption effects across

207 experimental control, based on generating a surrogate model to interpolate experimental data, and a

208 sensitivity by including the gradient of the surrogate model.

209 networks have become the method of choice in surrogate modeling because of their ability to character

210 roblem formulation to develop physics-driven surrogate models that generate synthetic IR spectra from

211 used to augment the training data for these surrogate models.

212 aches for assessing HuNoV infectivity (e.g., surrogates, molecular methods).

213 Ectromelia virus (ECTV) causes mousepox, a surrogate mouse model for smallpox caused by variola vir

214 This type of rapid, surrogate neutralization diagnostic can be employed wide

215 luble, Fzd subtype-specific "next-generation surrogate" (NGS) Wnts that hetero-dimerize Fzd and Lrp6.

216 brain blood are widely used as an fMRI-based surrogate of "resting-state" neuronal activity.

217 eable sites at the metal ion is re-cast as a surrogate of a coordinatively-unsaturated metalloenzyme

218 We used Pb(2+), a structural and functional surrogate of Ca(2+), to generate the protein states with

219 clopropanes with trimethylsilyl cyanide as a surrogate of cyanide ion in the presence of B(C(6)F(5))(

220 inic (CC) score, which is a semiquantitative surrogate of disease burden.

221 a direct indicator of renal injury, rather a surrogate of glomerular function.

222 n DNA repair, and positive immune score as a surrogate of interferon-primed exhausted CD8 + T-cells i

223 -Potentiation (LTP), an electrophysiological surrogate of learning and memory, but normal Abeta level

224 ry, and suppresses long-term potentiation, a surrogate of learning and memory.

225 monary artery occlusion pressure (a frequent surrogate of left atrial pressure) in this population.

226 ve dissolution in the presence of the chosen surrogate of natural organic matter, Suwannee river fulv

227 MRI)-derived specific ventilation maps as a surrogate of noble gas MRI and to validate this approach

228 e and prolonged retention of an 89Zr-labeled surrogate of PEG~TLZ in the MX-1 BRCA1-deficient tumor.

229 Antibody levels were related to a surrogate of protection based on preoutbreak serum antib

230 , or a simulated patient using a fluorescent surrogate of respiratory droplets.

231 estimate the skeletal muscle index (SMI), a surrogate of skeletal muscle mass, and to evaluate the s

232 Secretion of IL-1beta is a good surrogate of the differences observed, and thus to class

233 th and membranous septum length, an anatomic surrogate of the distance between the aortic annulus and

234 NGH is, therefore, a surrogate of tumor resilience but its quantification is

235 In rodent models of NAFLD, treatment with a surrogate of TVB-2640, a pharmacological fatty acid synt

236 or HFD feeding on beta-cell proliferation or surrogates of beta-cell mass, supports a secretion-speci

237 Noninvasive and hemodynamic surrogates of clinical risk identified cluster 1 as high

238 ly derived from oil, while others can become surrogates of petrochemical polymers due to their excell

239 hepatitis B core-related antigen (HBcrAg) as surrogates of silencing of covalently closed circular DN

240 rtheless, this compound was found to improve surrogates of social behavior in adults with autism spec

241 regard are numerous, and they target diverse surrogates of structural or tissue substrates of myocard

242 ral sugar derivatives are potential cyclitol surrogates of the Ca(2+)-mobilizing intracellular messen

243 luated, categorizing them as biomarkers, and surrogate or clinical endpoints.

244 approvals based on large-cohort trials with surrogate or intermediate clinical end points or on non-

245 We used plasma biomarkers as a surrogate outcome for ventilator-induced lung injury.

246 progression and serve as "quasi functional" surrogate outcome in clinical trials, especially in cons

247 the 3 morphologic factors and may serve as a surrogate outcome measure to monitor GA progression in f

248 d by a model that treated agency as a reward surrogate, over models that assigned utility only to mon

249 very of MaR1 reduced immediate postoperative surrogate pain score panels.

250 r nephrotoxic model identified thrombin as a surrogate pathway for complement activation in C3-defici

251 based on the electrochemical oxidation of a surrogate peptide combined with mass spectrometric measu

252 Our data showed that the results for surrogate peptide quantity measured by our method and by

253 Five CP4 EPSPS surrogate peptides and their corresponding retention tim

254 yrosine-containing peptides were selected as surrogate peptides for quantitation, considering the oxi

255 At least four of the five selected surrogate peptides were detected in nine of the products

256 eptide internal standards to quantify chosen surrogate peptides.

257 re radiolabeled with fluorine-18 and used as surrogate PET tracers of TD139 and GB1107.

258 Also, surrogate properties of early and intermediate endpoints

259 Based on the surrogate protective antibody cutoff, significantly more

260 t treats instrumental divergence as a reward surrogate provided a better account of male and female h

261 facial mechanical withdrawal thresholds as a surrogate readout of allodynia.

262 ary screening to measure GFP expression as a surrogate reporter of barrier integrity.

263 from blood while the monosaccharide (GB1107 surrogate) showed no sign of excretion.

264 p toward realizing the enormous potential of surrogate sires as a tool for dissemination and regenera

265 To monitor and manage biodiversity, surrogate species (i.e., indicator, umbrella and flagshi

266 iant mottled eel (A. marmorata) - can act as surrogate species for conservation of freshwater biodive

267 Hypercapnia, a surrogate state of depressed CA, leads to marked changes

268 In vivo evaluation revealed that both surrogates strongly differed with respect to their biodi

269 Kinetic studies with a surrogate substrate and spectroscopic analysis of a seri

270 ncer (BC) comprises four immunohistochemical surrogate subtypes of which triple-negative breast cance

271 They express PDX1, its surrogate surface marker P2RY1, and the bone morphogenet

272 atalyzes the regioselective cyclization of a surrogate synthetic substrate, Ant-l-Kyn-N-acetylcysteam

273 osine ((th)G) is an isomorphic guanosine (G) surrogate that almost perfectly mimics G in nucleic acid

274 oxy-MIDA-boronate is an excellent in situ CO surrogate that is tolerant of reactive functionalities s

275 This paper advocates for the training of surrogates that are 1) consistent with the physical mani

276 We find that these two consistencies lead to surrogates that are superior in terms of predictive perf

277 nt unseen seizure data and evaluated against surrogate time-series.

278 , solanesyl pyrophosphate (SPP) is used as a surrogate to bind a terpyridine zinc complex (Tpy-Zn), f

279 lkene and with 2-aminopyridine as an ammonia surrogate to give the Markovnikov addition product.

280 common postdonation outcome could serve as a surrogate to individualize counseling and management for

281 s suggest that (132)La is a suitable imaging surrogate to probe the in vivo biodistribution of (225)A

282 .g., cis-pinonic acid) are typically used as surrogates to quantify both monomeric and dimeric SOA co

283 These cells were further engineered with a surrogate tumor antigen to facilitate assays of T cell a

284 We found increased infiltration of both surrogate tumor antigen- and oHSV antigen-specific CD8+

285 Surrogate variable analysis (SVA)-based algorithms, are

286 we developed an R Shiny application [Visual Surrogate Variable Analysis (V-SVA)] that provides a web

287 correct for sex, age, library batches, and 1 surrogate variable component.

288 d based on the weight value derived from the surrogate variable is suitable for exploiting both diver

289 Solar radiation was used as the surrogate variable to determine the weight values for th

290 propose a weighted ensemble approach using a surrogate variable.

291 To facilitate the interpretation of surrogate variables detected by algorithms including IA-

292 of robust, scalable, and readily deployable surrogate viral assays to screen antiviral humoral respo

293 that uses synthetic DNA-lipid conjugates as surrogate viral receptors to tether virions to target ve

294 While each surrogate virus exhibited subtle differences in the sens

295 assay (ELISA) and a recently described novel surrogate virus neutralization test (sVNT).

296 The disaccharide (TD139 surrogate) was rapidly eliminated from blood while the m

297 p of an accurate yet extremely efficient DNN surrogate, we revealed the statistics of model responses

298 cids and dimer esters as more representative surrogates, we determine that molecular products measure

299 ithmetic mean ensemble (OAME) method and the surrogate weighted mean ensemble (SWME) method for three

300 Patients and surrogates were involved in round one and 12 of 27 respo