ライフサイエンスコーパス: susceptibility locus

1 fied TRAF1/C5 as a rheumatoid arthritis (RA) susceptibility locus.

2 the 17q12-21 locus, near a well-known asthma susceptibility locus.

3 connection between alpha-syn and another PD susceptibility locus.

4 ce that the IL2RA/CD25 gene represents a JIA susceptibility locus.

5 lable data and to identify a new keratoconus susceptibility locus.

6 the -707 site within the CRP gene is an SLE susceptibility locus.

7 s also a candidate in the murine Sle1c lupus susceptibility locus.

8 ve T cells in mice carrying the Sle1a1 lupus-susceptibility locus.

9 , was identified as a second Crohn's disease susceptibility locus.

10 cates a wide region and at least one disease-susceptibility locus.

11 96 x 10(-5)) tagged the PARK10 late-onset PD susceptibility locus.

12 e uncertainty surrounding the actual T1D MHC susceptibility locus.

13 pproach that models the marginal effect of a susceptibility locus.

14 ablishing its importance as a major vitiligo susceptibility locus.

15 closely flanking gene may be a tuberculosis-susceptibility locus.

16 owel disease (IBD), and TNF maps to the IBD3 susceptibility locus.

17 there is no convincing evidence of a common susceptibility locus.

18 autism families indicate the existence of a susceptibility locus.

19 precise chromosomal location for the disease-susceptibility locus.

20 tenic with the human 10q22-q23 schizophrenia-susceptibility locus.

21 ich find the xMHC to be the most significant susceptibility locus.

22 c lupus erythematosus, with IRF8 as a strong susceptibility locus.

23 tion that we have mapped to the Sle2c1 lupus susceptibility locus.

24 gene cluster on chromosome 2q37.1 as a novel susceptibility locus.

25 ocus of the NZM2410-derived Sle1 major lupus susceptibility locus.

26 oding CIKS has recently been identified as a susceptibility locus.

27 cate the orthologous human gene as a disease susceptibility locus.

28 B cells from mice carrying the Sle2c1 lupus susceptibility locus.

29 n ortholog of Ema, is a candidate autoimmune susceptibility locus.

30 cript that mapped to the human breast cancer susceptibility locus 17q12-q21 with unknown function.

31 from the PDED3 and MED24 genes at the asthma susceptibility locus 17q21 were associated with increase

32 tive immunity and genetic variants on asthma susceptibility locus 17q21.

33 H (CFH) and A69S in age-related maculopathy susceptibility locus 2 (ARMS2).

34 Previously, we localized PSORS2 (psoriasis susceptibility locus 2) to chromosomal region 17q25.3-qt

35 The major AF susceptibility locus 4q25 establishes long-range interac

36 selection plausibly acted on a human disease susceptibility locus, a form of balancing selection comp

37 etiological heterogeneity, with each genetic susceptibility locus accounting for only a small fractio

38 PSORS1 is the major susceptibility locus, accounting for approximately 33%-5

39 for linkage or association between a disease-susceptibility locus and a chromosome region in which se

40 the general population to a potential autism susceptibility locus and a linkage region for dyslexia,

41 perties of the networks, an established COPD susceptibility locus and domain-domain interactions invo

42 e functional landscape of the 11q23.3 glioma susceptibility locus and identify a network of functiona

43 in AFF2 may be a previously unrecognized ASD susceptibility locus and may help explain some of the ma

44 22.2-22.1 schizophrenia and bipolar disorder susceptibility locus, and additional neurodevelopmental

45 d within a recently mapped human lung cancer susceptibility locus, and association of the p34 A/G SNP

46 We thus identify a sexually dimorphic IS susceptibility locus, and propose the first functionally

47 enetic evidence that EN2 might act as an ASD susceptibility locus, and they suggest that a risk allel

48 We conclude that PTPRG is an ischemia susceptibility locus; and RPTPgamma-dependent sensing of

49 , we identified a 7 Mb interval containing a susceptibility locus (ANE1) in a family segregating recu

50 cases and 6732 controls, we identified a new susceptibility locus associated with overall PrCa risk a

51 , and confirmed the existence of a novel SLE susceptibility locus at 12q24 (designated "SLEB4") that

52 tudy provided evidence for a prostate cancer-susceptibility locus at 1q24-25.

53 n both subpopulations, and evidence of a new susceptibility locus at 2q37 was found in S2.

54 We have thus identified a novel susceptibility locus at 3p21, and confirmed previous sug

55 is result indicated that the type 2 diabetes susceptibility locus at 3q27 influences both genetic pre

56 We identified a new susceptibility locus at 4q22.1 in FAM13A and replicated

57 A candidate susceptibility locus at 6q23-25 for lung cancer was rece

58 leading to the identification of a confirmed susceptibility locus at 9p22 (in BNC2).

59 inkage analysis, we identified a keratoconus susceptibility locus at 9q34.

60 A novel RA susceptibility locus at AFF3 was identified with convinc

61 The location of a schizophrenia susceptibility locus at chromosome 22q11 has been sugges

62 The CLPTM1L gene lies within a cancer susceptibility locus at chromosome 5p15.33 defined by ge

63 ve colitis and identify a previously unknown susceptibility locus at ECM1.

64 In addition, we identified a new asthma susceptibility locus at PYHIN1, with the association bei

65 vidence supporting the presence of an asthma susceptibility locus at the proximal end of chromosome 1

66 e attributed to strong LD to another class I susceptibility locus (B*4403).

67 that the IL4RA gene is an atopy- and asthma-susceptibility locus but that variation outside the codi

68 2 was identified recently as a neuroblastoma susceptibility locus, but its mechanistic contributions

69 It maps to the PRC1 locus, a type 2 diabetes susceptibility locus, but its specific role in pancreati

70 AP, a gene adjacent to the familial melanoma susceptibility locus CDKN2A on 9p21 (rs4636294, combined

71 The diabetes susceptibility locus (chromosome 18p11) was systematical

72 type 2 diabetes and are consistent with one susceptibility locus common to obesity and diabetes.

73 Linkage to 17q22 syntenic to a susceptibility locus common to two experimental rat mode

74 Landers and Kruglyak), the power to detect a susceptibility locus could drop from 83.6% under a one-l

75 omprehensive analysis of a major albuminuria susceptibility locus detected in these models.

76 on studies (GWAS) have heralded a new era in susceptibility locus discovery in complex diseases.

77 d Hrh3 as a positional candidate for the EAE susceptibility locus Eae8.

78 A major JME susceptibility locus (EJM1) was mapped to chromosomal re

79 gene encoding complement factor 5 (C5) as a susceptibility locus for allergen-induced airway hyperre

80 These complex regions contain more than one susceptibility locus for allergic disease.

81 original hypothesis, that ABCR is a dominant susceptibility locus for AMD, by screening 1,218 unrelat

82 es identified chromosome 1q32 as harboring a susceptibility locus for AMD.

83 he IL4RA gene was examined as the 16p-linked susceptibility locus for asthma and atopy.

84 The authors recently mapped a susceptibility locus for autism to chromosome region 2q2

85 loss in autism, suggest SPRY3 as a candidate susceptibility locus for autism.

86 n orthologue of ema, Clec16A, is a candidate susceptibility locus for autoimmune disorders, and its e

87 ajor histocompatibility complex and AITD1, a susceptibility locus for autoimmune thyroid disease.

88 sults provide an example of a shared genetic susceptibility locus for bipolar disorder and MDD.

89 esults provide evidence of the presence of a susceptibility locus for BN on chromosome 10p.

90 These results strongly implicate 6q25.1 as a susceptibility locus for breast cancer.

91 romosome 6D3 and on human chromosome 3p14, a susceptibility locus for cancer and epilepsy.

92 ting cell growth suggests that PEG3 may be a susceptibility locus for cancer as well as neurobehavior

93 A susceptibility locus for coronary artery disease (CAD) a

94 A susceptibility locus for coronary artery disease (CAD) h

95 encoding fetuin-A, has been identified as a susceptibility locus for diabetes and metabolic syndrome

96 The QTL has further been supported as a susceptibility locus for dyslipidemia and related metabo

97 Thus, a heretofore unidentified genetic susceptibility locus for FHBL may reside on chromosome 3

98 ntitative trait mapping in mice identified a susceptibility locus for gallstones (Lith6) spanning the

99 common mutation, perhaps responsible for the susceptibility locus for genetic generalized epilepsy on

100 y, we observed the first example of a common susceptibility locus for genetic mosaicism, specifically

101 We have therefore identified a new susceptibility locus for HPS.

102 Although no major susceptibility locus for HSV-1 was identified, our resul

103 Beta(2)-adrenergic receptor (beta2-AR) is a susceptibility locus for hypertension, and polymorphisms

104 STAT4 is highly plausible as a susceptibility locus for invasive NTS disease.

105 kers in the VTCN1 gene defined an additional susceptibility locus for JIA and implicates a novel path

106 ed with corneal malformation, is a potential susceptibility locus for keratoconus.

107 IN1) gene within the second most significant susceptibility locus for late-onset AD.

108 A major susceptibility locus for leprosy has recently been mappe

109 e analysis consolidates clear evidence for a susceptibility locus for LOAD on 10q21.2.

110 indings support previous evidence of a major susceptibility locus for lung cancer and suggest that li

111 strongly implicated by genetic studies as a susceptibility locus for major mental illnesses.

112 histocompatibility molecules are the primary susceptibility locus for many autoimmune disorders, incl

113 esults confirm that MC1R is a low-penetrance susceptibility locus for melanoma, show that pigmentatio

114 We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10,

115 resent study thus identifies a novel genetic-susceptibility locus for MI and provides a framework for

116 kocyte antigen (HLA) region is the strongest susceptibility locus for MS, but a genome-wide associati

117 ATXN1 was recently nominated as a susceptibility locus for multiple sclerosis (MS).

118 oci, none overlaps with the newly identified susceptibility locus for myocardial infarction and coron

119 P = 1 x 10(-65)]; this interval represents a susceptibility locus for nephropathy.

120 FTO is the strongest known genetic susceptibility locus for obesity.

121 ased studies that indicated that SLC1A1 is a susceptibility locus for OCD.

122 1 (LOD=2.55) overlapping a recently reported susceptibility locus for ocular and cutaneous melanoma i

123 and 6,661 non-ALL controls, we identified a susceptibility locus for Ph-like ALL (GATA3, rs3824662;

124 (GeneQuest) identified a significant genetic susceptibility locus for premature myocardial infarction

125 rgely from Irish pedigrees, indicates that a susceptibility locus for psoriasis maps to chromosome 4q

126 PSORS1 is the major susceptibility locus for psoriasis vulgaris (PV) and lie

127 n leukocyte antigen-C gene likely contains a susceptibility locus for psoriasis.

128 At least 1 additional non-DRB1 susceptibility locus for RA exists in an interval that e

129 The identification of a susceptibility locus for refractive error on 15q25 will

130 chromosome 11q13.3, recently identified as a susceptibility locus for renal cell carcinoma, modulates

131 omplementary evidence for chromosome 8p as a susceptibility locus for schizophrenia, and suggest that

132 tion groups provide convergent support for a susceptibility locus for schizophrenia--and, more recent

133 rical P value of.012) and represents a novel susceptibility locus for schizophrenia.

134 roles in neurodevelopment and is a putative susceptibility locus for schizophrenia.

135 iption factor of HLA class II (HLA-II), at a susceptibility locus for several autoimmune diseases, in

136 itin-modifying enzyme A20, is an established susceptibility locus for SLE.

137 Recent linkage studies mapped a susceptibility locus for stuttering to chromosome 12 in

138 Sle is a susceptibility locus for systemic autoimmunity derived f

139 nectin gene is located in chromosome 3q27, a susceptibility locus for T2DM and metabolic disorders (S

140 The susceptibility locus for the autoimmune disease lupus on

141 We investigated whether the MBOAT7-TMC4 is a susceptibility locus for the development and progression

142 OXP2 has also been considered as a potential susceptibility locus for the language deficits in autism

143 ngenic mapping in NOD mice have identified a susceptibility locus for type 1 diabetes, Idd5.1 on mous

144 an chromosome 3q27, recently identified as a susceptibility locus for type 2 diabetes and the metabol

145 udies in Mexican-Americans localized a major susceptibility locus for type 2 diabetes, NIDDM1, to chr

146 esent cohort with UC, IBD5 may also act as a susceptibility locus for UC (chi2=8.10; P=.002).

147 n combination with KITLG, the strongest TGCT susceptibility locus found to date, men with TGCT had gr

148 ently, we demonstrated that the Friend virus susceptibility locus, Fv2, which is required for the exp

149 We identified a major susceptibility locus (HIVAN4) on chromosome 6 G3-F3, wit

150 gnosis of type 1 diabetes, sex, or the major susceptibility locus, HLA class II, remain mostly unexpl

151 pport for the existence of a prostate cancer-susceptibility locus HPC20 at 20q13.

152 has provided evidence for a prostate cancer-susceptibility locus, HPC20, which maps to 20q13.

153 chromosome 4 containing the type 1 diabetes susceptibility locus Idd9.2.

154 date for the type 1 diabetes mellitus (T1DM) susceptibility locus IDDM2.

155 orthologous to human 5q11.2, a breast cancer susceptibility locus identified in multiple genome-wide

156 Sle3/5 is a lupus susceptibility locus identified on mouse chromosome 7 of

157 hese results demonstrate evidence for a PRCA susceptibility locus in a subset of families that is dis

158 We evaluated 15-PDGH as a colon cancer susceptibility locus in a three-stage design.

159 implicated 10q22-q23 as a schizophrenia (SZ) susceptibility locus in Ashkenazi Jewish (AJ) and Han Ch

160 inkage studies yielded strong evidence for a susceptibility locus in HPC families.

161 disease has been used to identify a novel RA susceptibility locus in humans.

162 The results identify a novel mammary tumor susceptibility locus in mice and support a role for DMBT

163 d linkage analysis to identify a major HIVAN susceptibility locus in mouse, HIVAN1.

164 on of chromosome 7 was identified as a lupus susceptibility locus in MRL/Fas(lpr) mice as Lmb3.

165 Sle1 is a major lupus susceptibility locus in NZM2410 lupus model that is asso

166 entified a 3p21.31 gene cluster as a genetic susceptibility locus in patients with Covid-19 with resp

167 67 has recently been identified as an asthma susceptibility locus in subjects of European ancestry bu

168 ted significant evidence for a schizophrenia susceptibility locus in the Ashkenazim on chromosome 10q

169 We previously identified a disease-susceptibility locus in the BBDR rat, iddm4, which is as

170 he syntenic region of the glomerulosclerosis susceptibility locus in the BUF/Mna rat.

171 stablished the presence of a major psoriasis-susceptibility locus in the human leukocyte antigen (HLA

172 he interval containing PSORS1, the psoriasis-susceptibility locus in the major histocompatibility com

173 te gene for the Idd9.3 type 1 diabetes (T1D) susceptibility locus in the nonobese diabetic (NOD) mous

174 Sle1 is a major susceptibility locus in the NZM2410 murine model of syst

175 In earlier studies of the Iddm14 diabetes susceptibility locus in the rat, we identified an allele

176 nteraction between the major prostate cancer susceptibility locus in the subregion of 8q24 that conta

177 that the HLA region harbors a predominant CD-susceptibility locus in these Finnish families.

178 Identification of a susceptibility locus in this region may eventually lead

179 These results localize a major susceptibility locus influencing lung cancer risk to 6q2

180 The mouse T1D susceptibility locus insulin-dependent diabetes suscepti

181 xpected genotypic frequencies (delta) at the susceptibility locus is a function of the susceptibility

182 The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk

183 gene (MGEA5) is a documented human diabetes susceptibility locus, its role in maintaining insulin-gl

184 es have clearly identified a primary disease susceptibility locus lying within the major histocompati

185 This is the first time that an arthritis susceptibility locus mapped in experimental animal model

186 A combined analysis identified a novel susceptibility locus mapping to 2q22.3 marked by rs12105

187 Evidence has been presented for an RA susceptibility locus mapping under the linkage peak on 6

188 lated macular degeneration (AMD) wherein the susceptibility locus maps to chromosome 12q, a region be

189 genetic studies suggest that a schizophrenia susceptibility locus maps to chromosome 22q.

190 It is therefore clear that a schizophrenia susceptibility locus maps to chromosome 22q11.

191 tified the human/rat-conserved breast cancer susceptibility locus MCS5A/Mcs5a.

192 ed with the lpr mutation or the murine lupus susceptibility locus Nba2 causes dramatic B cell and PC

193 Given that the murine lupus susceptibility locus Nba2 includes the IFN-regulated gen

194 The murine lupus susceptibility locus Nba2 on chromosome 1 and the synten

195 With these data, we identified a susceptibility locus near TIMP3 (overall P = 1.1 x 10(-1

196 out, but apart from the well-established HLA susceptibility locus, none of the reported significant r

197 While the Sle1 lupus susceptibility locus of NZM2410/NZW origin leads to chro

198 tion studies have identified a breast cancer susceptibility locus on 16q12 with an unknown biological

199 e positional candidate for the schizophrenia-susceptibility locus on 1q22, although initial mutation

200 GWAS have identified a breast cancer susceptibility locus on 2q35.

201 report the discovery of a new endometriosis susceptibility locus on 4q12 (rs17773813[G], OR=1.28; P=

202 lymphocytic leukaemia (CLL) has identified a susceptibility locus on 6p25.3 associated with a modest

203 imity to the previously reported lung cancer susceptibility locus on 6q.

204 SCR inheritance, a genome scan reveals a new susceptibility locus on 9q31 exclusively in group II fam

205 Mice with the Sle3 lupus-susceptibility locus on a wild-type background were foun

206 likely due to a mutation in a major diabetes susceptibility locus on Chr 19, which interacts with add

207 ndition in Europeans and implicating a novel susceptibility locus on chromosome 1.

208 and resistant (FVB/N ApoE0) mice revealed a susceptibility locus on chromosome 10 (11 cM, logarithm

209 reports, our data support evidence for a DN susceptibility locus on chromosome 10.

210 e independently identified a prostate cancer susceptibility locus on chromosome 10q11.2.

211 n by age at diagnosis highlighted a putative susceptibility locus on chromosome 11, among the later-o

212 ovide further evidence for a prostate cancer susceptibility locus on chromosome 15q and demonstrate t

213 ols of Japanese populations, we identified a susceptibility locus on chromosome 15q24.

214 s evidence for the IBD1 Crohn's disease (CD) susceptibility locus on chromosome 16 in several but not

215 A strands flanking a Multiple Sclerosis (MS) susceptibility locus on Chromosome 17q24.

216 revealed linkage to a previously unreported susceptibility locus on chromosome 18p11.

217 with FVBN mice mapped to an atherosclerosis susceptibility locus on chromosome 19 revealed in an int

218 y, the Piasy gene is localized in the PSORS6 susceptibility locus on chromosome 19p13, and Piasy nega

219 uggestive evidence for the presence of an AN-susceptibility locus on chromosome 1p.

220 young-onset (aged <45 years) type 2 diabetes susceptibility locus on chromosome 1q21-q23.

221 ts of previous studies for the presence of a susceptibility locus on chromosome 1q21-q25 (173.9 cM) a

222 A previous GWAS reported a possible TGCT susceptibility locus on chromosome 1q23 in the UCK2 gene

223 upporting the existence of a type 1 diabetes susceptibility locus on chromosome 1q42 and identify a c

224 significant evidence for an early-onset COPD-susceptibility locus on chromosome 2 and suggestive evid

225 lity 1 (Pas1) is the major mouse lung cancer susceptibility locus on chromosome 6.

226 nkage data reinforce the evidence of a major susceptibility locus on chromosome 6.

227 ded unambiguous evidence for a major disease susceptibility locus on chromosome 6p21 (PSORS1).

228 ings provide evidence for linkage to a novel susceptibility locus on chromosome 6p23.

229 from Sudan and Brazil identified a putative susceptibility locus on chromosome 6q27.

230 The putative autism-susceptibility locus on chromosome 7 may be the result o

231 American family showed evidence for a keloid susceptibility locus on chromosome 7p11 (maximal two-poi

232 nclusion, our data support a type 2 diabetes susceptibility locus on chromosome 8p that appears to be

233 re is evidence of linkage to a schizophrenia susceptibility locus on chromosome 8p21-22 found by seve

234 nalysis identified one novel significant RLS-susceptibility locus on chromosome 9p24-22 with a multip

235 (1) confirm the previously reported obesity-susceptibility locus on chromosomes 3, 7, and 17 and (2)

236 for NZB autoimmunity 2 (Nba2), a NZB-derived susceptibility locus on distal chromosome 1, produce aut

237 tudies uncovered a major atrial fibrillation susceptibility locus on human chromosome 4q25 in close p

238 idence in inbred mice and identified a major susceptibility locus on mouse chromosome 2 (rs27328255,

239 HIVAN and demonstrate a major renal disease susceptibility locus on mouse chromosome 3A1-3.

240 An NZM2410-derived lupus susceptibility locus on murine chromosome 4, Sle2(z), ha

241 Sle3 is an NZM2410-derived lupus susceptibility locus on murine chromosome 7.

242 ly inherited, but only one recessive genetic susceptibility locus, on chromosome 7p, has been identif

243 To map more precisely the susceptibility locus (or loci) within this broad region,

244 inkage disequilibrium with an unknown nearby susceptibility locus, or a direct maternal effect alone.

245 A second SNP tagged the PARK11 late-onset PD susceptibility locus (P=1.70 x 10(-5)).

246 genetic variation at CSMD1, a schizophrenia susceptibility locus, plays a role in the ratio between

247 Previous studies mapped one promotion susceptibility locus, Psl1, to distal chromosome 9.

248 viously recognized as containing a psoriasis susceptibility locus, PSORS5.

249 t lie within Idd (insulin-dependent diabetes susceptibility locus) regions, which are known to contai

250 s of 1,852 pedigrees, that a type 2 diabetes susceptibility locus resides on chromosome 20q.

251 A novel PD susceptibility locus, RIT2, on chromosome 18 (rs12456492

252 INTERPRETATION: We identified a novel PD susceptibility locus, RIT2, replicated several previousl

253 not only confirmed the association of a PrCa susceptibility locus, rs11672691 on chromosome 19, but a

254 de association study (GWAS) has identified a susceptibility locus (rs41270488) for HPV8 seropositivit

255 scovery of the first genome-wide significant susceptibility locus (rs4769613; P = 5.4 x 10(-11)) in 4

256 es of rheumatoid arthritis (RA) identified a susceptibility locus, rs874040(CC), which implicated the

257 ic mouse strains to map the major skin tumor susceptibility locus Skts1 within a genetic interval of

258 Ola)F1 backcrosses, to identify a skin tumor susceptibility locus, Skts14, on proximal chromosome 7.

259 or murine systemic lupus erythematosus (SLE) susceptibility locus Sle1 is syntenic to a chromosomal r

260 ematosus (SLE) modifiers yaa and lpr and the susceptibility locus Sle1.

261 or murine systemic lupus erythematosus (SLE) susceptibility locus, Sle1, corresponds to three loci in

262 e Pbx1 that corresponds to the NZM2410 lupus susceptibility locus Sle1a1.

263 J is prone to absence seizures, with a major susceptibility locus, spkw1, accounting for most of the

264 ith severe lung tissue damage mediated by TB-susceptibility locus sst1.

265 not yet provided convincing evidence for any susceptibility locus subject to parent-of-origin effects

266 The human IGRP gene maps to a diabetes susceptibility locus, suggesting that IGRP also may be a

267 of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polym

268 nificant linkage of an oligogenic autoimmune susceptibility locus, termed AIS1, to a 14.4 cM interval

269 A major susceptibility locus, termed the Gvh1 locus, was identif

270 eptor 1 (CR1) is an Alzheimer's disease (AD) susceptibility locus that also influences AD-related tra

271 the risk variant in the PSORS1 [MIM 177900] susceptibility locus that confers the greatest risk for

272 e polymorphisms in lncRNAs, such as the 9p21 susceptibility locus that encodes the lncRNA antisense n

273 Sle2 is a lupus susceptibility locus that has been linked to glomerulone

274 Sle2c1 is an NZM2410- and NZB-derived lupus susceptibility locus that induces an expansion of the B1

275 , sex, and smoking status identified a novel susceptibility locus that mapped to a region of 18q12.3,

276 When we combine Tg7 with the Sle1 lupus susceptibility locus, the mice develop severe disease.

277 In addition to identifying a new melanoma-susceptibility locus, this is to our knowledge the first

278 for all phenotypes conferred by murine viral susceptibility locus Tmevp3.

279 , using a mouse model based on the human SLE susceptibility locus TNFAIP3-interacting protein 1 (TNIP

280 e a mouse model based on the human psoriasis susceptibility locus TNIP1, also referred to as ABIN1, w

281 We mapped a previously unknown susceptibility locus to 2q37.1 and identified germline m

282 one large family of a presumptive strabismus susceptibility locus to 7p22.1 with a multipoint logarit

283 previous genome scan mapped a primary hip OA susceptibility locus to chromosome 2q with a maximum mul

284 were coupled to position a new hypertension-susceptibility locus, uncovering a previously unsuspecte

285 report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 600 contr

286 One novel significant susceptibility locus was detected for MI on chromosomal

287 The strongest evidence for an AMD susceptibility locus was found on chromosome 10q26 where

288 < 0.00002), the strongest evidence for an RA susceptibility locus was found on chromosome 16 (P = 0.0

289 cdkn2c gene encoding p18(INK4c) within a SLE susceptibility locus was found to account for reduced p1

290 lications compared with C57BL/6J, and a BALB susceptibility locus was mapped by linkage analysis to c

291 Linkage to a prostate cancer susceptibility locus was recently reported on chromosome

292 HeJ congenic mice in which the H2k purported susceptibility locus was replaced with the H2b purported

293 rbors the factor H gene (HF1/CFH), as an AMD susceptibility locus, we analyzed HF1 for genetic variat

294 To identify an additional RCC common susceptibility locus, we conducted a GWAS and performed

295 l dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) ris

296 dence for significant association of a lupus susceptibility locus, which has been mapped to a chromos

297 Sle1a.1 is part of the Sle1 susceptibility locus, which has the strongest associatio

298 er to detect the gene underlying the disease-susceptibility locus, which hold regardless of the linka

299 he telomeric end of the NZM2410-derived Sle2 susceptibility locus, which we named Sle2c2.

300 For example, for a disease susceptibility locus with minor allele frequency of 15%,