ライフサイエンスコーパス: susceptibility to

1 Sedentary time was related to lower susceptibility to a framing bias.

2 tical in determining bacterial resistance or susceptibility to a particular antibiotic.

3 at stroke (EHS) has been linked to increased susceptibility to a second heat stroke, infection and ca

4 Susceptibility to a second-line regimen was significantl

5 nregulation of miR-218 in the mPFC increases susceptibility to a single session of social defeat, whe

6 genetic factors may significantly influence susceptibility to A(H7N9) infection.

7 ing and regenerative capacity, and increased susceptibility to acute and chronic lung diseases.

8 ophil-macrophage imbalance in promoting host susceptibility to acute pyelonephritis and the developme

9 the neurobiological mechanisms that mediate susceptibility to addiction.

10 Genetic characteristics may contribute to susceptibility to adverse outcomes including sepsis and

11 ific genes, and specific variants increasing susceptibility to AF.

12 e stress, thus reducing I(Na), and enhancing susceptibility to AF.

13 ants explains a larger proportion of genetic susceptibility to AF.

14 vo, and during biofilm growth it has reduced susceptibility to all three classes of contemporary anti

15 The susceptibility to alpha-amylolysis together with the iod

16 Streptococcus pyogenes strains with reduced susceptibility to ampicillin, amoxicillin, and cefotaxim

17 Lower PGE(2) levels and higher susceptibility to anaphylaxis were also found in C57BL/6

18 eroxisome-ether-phospholipid axis in driving susceptibility to and evasion from ferroptosis, highligh

19 ensity, recency of past illnesses, perceived susceptibility to and perceived severity of an infection

20 iome is increasingly implicated in modifying susceptibility to and progression of neurodegenerative d

21 nt factors in our lifestyle, and confer both susceptibility to and protection from a variety of human

22 Susceptibility to and severity of COVID-19 in cancer pat

23 Factors determining susceptibility to and severity of RSV disease in adults

24 igen A [HLA-A], -B, and -C genes) may affect susceptibility to and severity of the disease caused by

25 ty will be critical for our understanding of susceptibility to and the natural course of SARS-CoV-2 i

26 flammatory genes in DTPs and thereby confers susceptibility to anti-inflammatory glucocorticoids (GCs

27 t staphylococcal strains that have decreased susceptibility to antibiotics; however, little is known

28 ol intake that might contribute to increased susceptibility to anxiety and alcohol abuse in men.

29 obesity there was also a slight increase in susceptibility to any H1N1pdm infection (OR: 1.20, 95%CI

30 a trachomatis infection, HeLa cells regained susceptibility to apoptosis induction following staurosp

31 O) HAP1 (human haploid) cells and reduce the susceptibility to apoptosis.

32 dipogenesis and increasing gluteal adipocyte susceptibility to apoptosis.

33 nsect body size is an important predictor of susceptibility to aqueous metals.

34 ion system pathology that could increase the susceptibility to arrhythmias and sudden cardiac death i

35 Susceptibility to at least 1 second-line regimen was pre

36 ever, the mechanism underlying the increased susceptibility to atrial alternans in HF remains incompl

37 uced atrial electrical remodelling increased susceptibility to atrial alternans mainly due to the inc

38 Susceptibility to atrial fibrillation (AF) is determined

39 in mice causes atrial fibrosis and increases susceptibility to atrial fibrillation.

40 that lack of DO increases autoreactivity and susceptibility to autoimmune disease development.

41 ociations between genetic loci and increased susceptibility to autoimmune disease have been well char

42 ing that p73 dysregulation may contribute to susceptibility to autoimmune disease.

43 jor histocompatibility complex II-associated susceptibility to autoimmune diseases acuminates in a pr

44 ental autoimmune encephalitis, mirroring the susceptibility to autoimmune diseases seen in people wit

45 ginosa or Enterobacteriaceae were tested for susceptibility to aztreonam, ceftazidime, and meropenem;

46 al presentations, characterized by increased susceptibility to bacterial and viral infections and (to

47 essive regimens are used, which can increase susceptibility to bacterial and viral infections.

48 iagnostic tool for assessing host microbiota susceptibility to bacterial colonization after key antib

49 w genetics contributes to host resistance or susceptibility to bacterial infection.

50 ophages, resulting in genetically programmed susceptibility to bacterial infection.

51 te smoke damages host defenses and increases susceptibility to bacterial infections.

52 hat TARK1 OE in leaves resulted in increased susceptibility to bacterial invasion.

53 iation, which increases disease severity and susceptibility to bacterial superinfections.

54 idic protein-a mutation that confers reduced susceptibility to baloxavir marboxil-from patients befor

55 tors which thus may indirectly modulate host susceptibility to Bd.

56 tococcus pyogenes with significantly reduced susceptibility to beta-lactam antibiotics have been rece

57 ds aimed at maximizing rigour and minimizing susceptibility to bias.

58 d Crohn's disease (CD), some of which confer susceptibility to both diseases.

59 an MHCII-dependent mechanism which enhances susceptibility to Brucella infection.

60 n in prion susceptible species) resulting in susceptibility to BSE-derived isolates.

61 urbances caused by diarrhoeal events trigger susceptibility to C. difficile colonization.

62 ce (LRP5/6(DeltaCD11c)) resulted in enhanced susceptibility to CAC.

63 Although susceptibility to cardiovascular disease (CVD) is differ

64 he influence of the myocardial trabeculae on susceptibility to cardiovascular disease.

65 lacking either UL36 or M36, exhibit greater susceptibility to CD8 T cell control than mutants lackin

66 ntrols, and metabolic changes associate with susceptibility to CDI.

67 to consideration when in vitro antimicrobial susceptibility to cefiderocol is determined.

68 However, the genetic basis of reduced susceptibility to ceftriaxone is not completely understo

69 turbations in vitro, thereby explain horses' susceptibility to certain neurodegenerative diseases.

70 mice, residual eosinophilia was ablated, and susceptibility to chronic adult Brugia malayi infection

71 The proportion of Neisseria with reduced susceptibility to ciprofloxacin was 93%, cefpodoxime 84%

72 scular function in vitro and in vivo and the susceptibility to CKD in rats with wild-type or mutated

73 Obese BMI status appears to increase susceptibility to classroom NO(2) exposure effects on as

74 red NK cell maturation in a child with fatal susceptibility to CMV.

75 host genetics and gut microbiota modulating susceptibility to CNS autoimmunity, providing insights i

76 the initial viral infection can affect host susceptibility to coinfections.

77 To directly test the impact of diarrhoea on susceptibility to colonization, we developed a mouse mod

78 NADPH generation, lipid metabolism, and the susceptibility to colorectal tumorigenesis.

79 ores (PRSs) have shown promise in predicting susceptibility to common diseases(1-3).

80 f the foot muscles and possibly to increased susceptibility to common pathological conditions such as

81 investigated the association of the genetic susceptibility to complex traits with human lifespan in

82 ty effect might be related to differences in susceptibility to COVID-19 and access to health care (in

83 CE2 expression levels could be important for susceptibility to COVID-19 or its outcomes.

84 To examine susceptibility to COVID-19, a Cox regression model with

85 The mechanisms underlying the susceptibility to critical illness are poorly understood

86 nockout adult flies exhibit enhanced disease susceptibility to DCV and bacteria.

87 er miR-218 in the mPFC confers resilience or susceptibility to depression-like behaviors in adult mic

88 ikely a critical disease modifier, promoting susceptibility to depression.

89 AI-2, as AI-2 administration did not promote susceptibility to depressive-like behaviors or SAA1 and

90 disrupted junctional proteins, and increased susceptibility to develop AD.

91 of airway epithelial barrier function in the susceptibility to develop asthma and novel insights in t

92 K4 have been genetically linked to increased susceptibility to developing schizophrenia, a devastatin

93 MICA*045 and MICB*004 associated with susceptibility to DHF in secondary dengue virus (DENV) i

94 The PRS predicted the susceptibility to DILI in patients treated with fasiglif

95 ' is essential to understanding variation in susceptibility to disease and functional decline.

96 al effect of primary viral infections in the susceptibility to disease exacerbation in response to a

97 mbiotic bacteria in holobiont resistance and susceptibility to disease remains less well understood.

98 Human ageing is associated with high susceptibility to disease.

99 Susceptibility to diseases is common to humans and dinos

100 To further elucidate genetic susceptibility to DLBCL, we sought to validate two loci

101 eloping nervous system, including windows of susceptibility to DomA exposure, structural and molecula

102 n zebrafish reveal a developmental window of susceptibility to DomA-induced behavioral deficits and i

103 pithelial barrier integrity, leading to high susceptibility to DSS-induced colitis.

104 upport a role for genetic risk prediction of susceptibility to elevated IOP that may not be apparent

105 d-line regimen was preserved in 59%, as were susceptibility to etravirine (78%) and darunavir/ritonav

106 trapment in the electrophoresis well and low susceptibility to exonucleases revealed that the biologi

107 like3 (DCL3, but not DCL2 or DCL4) increased susceptibility to F brachygibbosum The relevance of AGO4

108 However, precisely how susceptibility to ferroptosis is dynamically regulated r

109 ey (cv. Conlon) orthologue, Hv2OGO, restored susceptibility to Fg.

110 nce, may have a similar role in conditioning susceptibility to FHB in barley.

111 mperfecta (OI) is characterized primarily by susceptibility to fractures with or without bone deforma

112 regimes in ways that could increase corals' susceptibility to further stressors.

113 ression in HepG2 significantly increased its susceptibility to HCoV-OC43 infection.

114 ac structure and function leads to increased susceptibility to heart failure.

115 xpression and ligand binding but changed the susceptibility to heat denaturation: the thermodynamic s

116 ment of ILC2(INFLAM) responses and increased susceptibility to helminth infection.

117 h by-products are needed based on their high susceptibility to hemoglobin (Hb)-mediated lipid oxidati

118 cific and pan-CoV host factors that regulate susceptibility to highly pathogenic CoVs.

119 mation known to be associated with increased susceptibility to HIV infection.

120 dy, we investigated, for the first time, Tfh susceptibility to HIV-2 infection by combining in vitro

121 paired induction of type I IFN and increased susceptibility to human cytomegalovirus (HCMV) infection

122 he formation of isopeptide bonds with varied susceptibilities to hydrolysis or exchange by mTG.

123 Despite increased susceptibility to IFN-alpha, NT viruses produced more vi

124 MPRSS6 gene that is hypothesized to heighten susceptibility to IL-6-mediated inflammatory effects.

125 Heterozygous adults displayed susceptibility to induced generalized seizures, hyperact

126 proliferation in vitro, as well as increased susceptibility to induction of cancer in vivo.

127 ays that involve IL-6 and TNF-alpha increase susceptibility to infection among individuals with CKD.

128 lls contribute to a higher risk of increased susceptibility to infection and development of chronic d

129 activating protease TMPRSS2 further enhanced susceptibility to infection by 5- to 10-fold.

130 AtFH overexpressor lines displayed decreased susceptibility to infection by host pathogen P syringae

131 ver, the effects of endocannabinoids on host susceptibility to infection has not been explored.

132 We estimate that susceptibility to infection in individuals under 20 year

133 ergent immune responsiveness to vaccines and susceptibility to infection observed during early life.

134 don't understand the influence of obesity on susceptibility to infection or on non-severe influenza o

135 nnate immune response resulting in increased susceptibility to infection that may be partially rescue

136 burden, indicating that B cells only enhance susceptibility to infection when T cells are present.

137 echanisms (tissue recovery and variable cell susceptibility to infection), using our software modules

138 ificantly disrupts immunity, thus increasing susceptibility to infection, a leading cause of morbidit

139 en age, contact patterns, social distancing, susceptibility to infection, and COVID-19 dynamics remai

140 l sex differences may manifest themselves in susceptibility to infection, early pathogenesis, innate

141 could be explained by children having lower susceptibility to infection, lower propensity to show cl

142 4(+) T cells and macrophages determine their susceptibility to infection, the persistence of infected

143 Although other non-pulmonary organs showed susceptibility to infection, their contribution to the p

144 those in early lactation, and increase their susceptibility to infection.

145 pping the scale between brain protection and susceptibility to infection.

146 ll data effectively classified and predicted susceptibility to infection.

147 myriad of phenotypes that may modulate their susceptibility to infection; however, the precise determ

148 Mechanisms underlying increased susceptibility to infections are poorly understood.

149 alities that may be related to the increased susceptibility to infections observed in these patients.

150 pulmonary disease (COPD) increase patients' susceptibility to infections, but it is unclear how the

151 VID) is a disease characterized by increased susceptibility to infections, hypogammaglobulinemia, and

152 onent, including cardiovascular diseases and susceptibility to infections.

153 Understanding the genetics of susceptibility to infectious agents is of great importan

154 COVID-19) pandemic, investigations into host susceptibility to infectious diseases and downstream seq

155 Susceptibility to infectious diseases is determined by a

156 ss to safe water and healthcare can increase susceptibility to infectious diseases, particularly amon

157 ences in T helper (Th) cell responses affect susceptibility to infectious, allergic and autoimmune di

158 mportant role in attributes like firmness or susceptibility to infestations, rots and mechanical dama

159 ver, the mechanisms underlying the increased susceptibility to inflammation induced by the loss of DR

160 a(+ )T(reg) cell counts and ameliorates host susceptibility to inflammatory colitis via BA nuclear re

161 rI], 9-69%) and 25% (95% CrI, 0.5-42%) lower susceptibility to influenza A(H3N2) infection, respectiv

162 lucitol levels decreased in males indicating susceptibility to insulin resistance.

163 We then tested the newly formed memory's susceptibility to interference.

164 ow microbial diversity confers resistance or susceptibility to intestinal pathogens is poorly underst

165 CRG and PRKN polymorphisms with an increased susceptibility to intracellular pathogens.

166 es including model initialization (landscape susceptibility to invasion) and expert-identified ecolog

167 ing protein (TOLLIP) are associated with the susceptibility to IPF and mortality.

168 DEPTOR expression associates with increased susceptibility to IPF supports recent studies demonstrat

169 identifies biomarkers that predict enhanced susceptibility to JNK inhibition.

170 learning in the cerebellum, which predicted susceptibility to later fear reinstatement.

171 y and behavior play a role in predetermining susceptibility to later stress, providing insight into m

172 56 gene at positions associated with reduced susceptibility to LET based on resistance selections in

173 ic viral RNA induces barrier damage, causing susceptibility to lethal bacterial superinfections.

174 elderly, and this phenomenon is connected to susceptibility to leukaemic transformation.

175 Susceptibilities to levofloxacin and TMP-SMZ were 29.3%

176 igh volatility, low solubility in water, and susceptibility to light, heat and oxygen degradation.

177 Here, we show that heterogeneity in susceptibility to Listeria monocytogenes infection among

178 our results indicate that VPA increases the susceptibility to Listeria monocytogenes infection and s

179 c rice causes ambivalent immunity: increased susceptibility to M. oryzae and Xanthomonas oryzae pv. o

180 isorder, we investigated whether a polygenic susceptibility to major depression is associated with re

181 y an important role in modulating the female susceptibility to mating.

182 ing candidate gene underlying resistance and susceptibility to MD in view of its function and overlap

183 ombinant congenic strains (RCSs) with varied susceptibility to MD, are considered as ideal models to

184 s suggests that factors other than age shape susceptibility to medically attended infection.

185 protease inhibitory activity of LEKTI or its susceptibility to mesotrypsin degradation.

186 Susceptibility to metabolic diseases may be influenced b

187 position of the intestinal microbiota and in susceptibility to metabolic, autoimmune, and neoplastic

188 Different wood species demonstrated varying susceptibility to microbial growth after 3 weeks and vis

189 rent zooplankton species may influence their susceptibility to microplastic ingestion.

190 ks are an understudied group regarding their susceptibility to microplastic ingestion.

191 ual reactivation was associated with reduced susceptibility to misinformation, whereas stronger audit

192 y reactivation was associated with increased susceptibility to misinformation.

193 in human HEK293T epithelial cells conferred susceptibility to MNV infection.

194 Y, IL37, and NCR2 genes were associated with susceptibility to moderate or severe periodontitis; wher

195 ion within the breed relates to an increased susceptibility to musculoskeletal disorders.

196 ed DC functionality contributes to Mendelian susceptibility to mycobacterial disease upon SPPL2a defi

197 humans, absence of SPPL2a leads to Mendelian susceptibility to mycobacterial disease, which is attrib

198 e established that mutations in LRRK2 confer susceptibility to mycobacterial infection, suggesting LR

199 fering a more complete understanding of drug susceptibility to Mycobacterium tuberculosis.

200 ral progeny may contribute to their enhanced susceptibility to neurodegenerative diseases characteriz

201 iculty to deliver them into cancer cells and susceptibility to nuclease degradation.

202 lammatory antioxidant, attenuates programmed susceptibility to obesity and insulin resistance in offs

203 dies have focused on identifying the genetic susceptibility to obesity, we performed a GWAS on metabo

204 d during cohousing experiments and evaluated susceptibility to oral inflammatory disease in mice harb

205 ale transcriptional changes without altering susceptibility to other antibiotics, reducing growth rat

206 e immune suppression, resulting in increased susceptibility to other infectious diseases.

207 A mutant, and this correlated with increased susceptibility to oxacillin and DCS.

208 ngredients, which can increase the product's susceptibility to oxidation.

209 imited due to high volatility, and increased susceptibility to oxidation.

210 model based on the physiologic outcome of CE susceptibility to oxidative stress by demonstrating that

211 date genes significantly changed mosquitoes' susceptibility to P. falciparum.

212 ted with lower SMAD5 expression may increase susceptibility to PAH.

213 netic variation in LRRK2 associates with the susceptibility to Parkinson's disease, Crohn's disease,

214 Heightened susceptibility to peer influence and hypersensitivity to

215 d Ly6c(Lo) non-classical monocytes determine susceptibility to perinatal hepatic inflammation in late

216 een the host and its microbiota and increase susceptibility to periodontal diseases.

217 ociation of seven SNPs as genetic markers of susceptibility to periodontitis in a Brazilian populatio

218 om 379 enrolled patients were available with susceptibility to piperacillin/tazobactam 94% and merope

219 d with gravidity, likely driven by declining susceptibility to placental infection.

220 growth rate and stress responses, including susceptibility to plant RNA viruses.

221 acteria clearance and thereby causes extreme susceptibility to pneumococcal infection.

222 stem is that its nonenzymatic nature and its susceptibility to polyphosphatases make it potentially s

223 nhibits neutrophil recruitment and increases susceptibility to postinfluenza invasive pulmonary asper

224 y reshapes the leaf microbiome and increases susceptibility to potential bacterial pathogens.

225 urces become available would reduce juvenile susceptibility to predation and climatic factors overwin

226 eptibility, and 16 substitutions reduced RSV susceptibility to presatovir (2.9- to 410-fold).

227 Several other factors, including susceptibility to proteasome cleavage, peptide transport

228 hemolymph, Tsf1 mutants exhibited increased susceptibility to Pseudomonas bacteria and Mucorales fun

229 ted with cannabis use disorder and increased susceptibility to psychiatric illness.

230 nd killing functions of neutrophils, causing susceptibility to pulmonary A. fumigatus infection.

231 immunosuppressive, contributing to increased susceptibility to pulmonary infections in smokers, ex-sm

232 ing, increased tiller numbers, and increased susceptibility to R. solani.

233 iencies have been defined based on increased susceptibility to recurrent and/or severe infections.

234 virus polymerase conferred low-level reduced susceptibility to remdesivir.

235 renal tubules and markedly increasing their susceptibility to renal injury.

236 ional impairments that may affect the host's susceptibility to respiratory infections.

237 sed vulnerability to amino acid deprivation, susceptibility to retinal degeneration caused by endopla

238 3 (CDHR3) receptor which underlies variable susceptibility to rhinovirus-C infection and is associat

239 up antigen expression and is associated with susceptibility to rotavirus diarrhea, with non-secretors

240 classical monocytes in this setting restored susceptibility to RRV-mediated disease.

241 study of ICS use as a predictor of decreased susceptibility to SARS-CoV-2 infection and decreased COV

242 d Alzheimer's disease) may present increased susceptibility to SARS-CoV-2 infection and/or achieve se

243 cell-depleting therapies that might increase susceptibility to SARS-CoV-2 infection but reduce the ri

244 I receptor blockers (ARBs) does not increase susceptibility to SARS-CoV-2 infection through enhancing

245 SLC35B2 in these cells fully restored their susceptibility to SBV infection.

246 R by rapamycin reduced immunosuppression and susceptibility to secondary Candida infection.

247 r deleting TNFR2 during sepsis decreased the susceptibility to secondary infection.

248 induces CD4+ T-cell impairment and increases susceptibility to secondary pneumonia.

249 Importantly, the enhanced susceptibility to seizures, accompanied by an alteration

250 role of primary immunodeficiencies (PID) in susceptibility to sepsis remains unknown.

251 viral infection may contribute to increased susceptibility to several neurological diseases, such as

252 y at least partially explain their increased susceptibility to severe immune-mediated morbidities.

253 Susceptibility to SLE is multifactorial, with a combinat

254 VDR(DeltaPC) mice also showed high susceptibility to small intestinal injury induced by ind

255 l factor in determining individual levels of susceptibility to social stress and suggest that targeti

256 Moreover, we found that susceptibility to social stress decreased the firing act

257 , including high quantum yield (Phi(u)), low susceptibility to spontaneous hydrolysis in the dark, an

258 citability after injury, including increased susceptibility to spreading depolarizations (SDs) and se

259 able but display reduced locomotor activity, susceptibility to starvation, elevated glucose, and an a

260 seizure susceptibility; however, it reduced susceptibility to status epilepticus.

261 that is dependent on testosterone and causes susceptibility to stress in female mice.

262 study identifies a novel molecular marker of susceptibility to stress-induced anhedonia, a core sympt

263 SN-specific CRY-knockdown in the NAc reduced susceptibility to stress-induced helplessness and increa

264 rasite Podosphaera plantaginis and measuring susceptibility to subsequent infection during experiment

265 Given the strong cancer susceptibility to subtle reductions in PTEN, the ability

266 ch, we assessed capuchin and rhesus monkeys' susceptibility to sunk costs in a psychomotor task.

267 nd cell wall composition could influence the susceptibility to surface pitting.

268 was also linearly associated with increased susceptibility to symptomatic H1N1pdm infection, primari

269 lation seen in STAT3 LOF patients suggests a susceptibility to systemic autoimmunity with important i

270 ased tissue damage, and early (within 3-6 d) susceptibility to systemic L. monocytogenes infection.

271 n an ex vivo platform that recreates genetic susceptibility to T-cell-mediated damage.

272 anoid-based platform that re-creates genetic susceptibility to T-cell-mediated tissue injury as obser

273 scenarios, while we detected differences in susceptibility to technical bias.

274 basis for strain-specific inherent baseline susceptibility to the antibiotic para-aminosalicylic aci

275 a function of mutational load and population susceptibility to the cluster--along with the variance i

276 rences can impart either enhanced or blunted susceptibility to the effects of such pathogenic environ

277 ry of replication-competent virions with low susceptibility to the inhibitor.

278 for further mechanistic studies of distal TE susceptibility to the malignant transformation.

279 psis thaliana resulted in plants showing low susceptibility to the RKN Meloidogyne incognita.

280 the wider adoption of biopesticides is their susceptibility to the ultraviolet (UV: 290-400 nm) radia

281 with genes whose expression correlates with susceptibility to this drug across glioma cell lines, re

282 n and reduced senescence markers, confirming susceptibility to transformation.

283 Together, our studies demonstrate that susceptibility to traumatic stress is associated with a

284 Results indicate that susceptibility to traumatic stress is associated with al

285 h-old DIABIMMUNE study participants with HLA susceptibility to type 1 diabetes were collected.

286 onstrate that the human AMP LL-37 lowers the susceptibility to vancomycin in the community-associated

287 volution towards NICU specialization and non-susceptibility to vancomycin, indicating convergent evol

288 These cellular genes contribute to lytic susceptibility to various degrees.

289 red gene regulation in the prenatal brain in susceptibility to various neuropsychiatric disorders and

290 e show that SNX5 deletion increases cellular susceptibility to viral infection in vitro, and that Snx

291 a T(H)2 cell-dominated immune response, and susceptibility to viral skin infections that are normall

292 lls may be involved in tumor progression and susceptibility to virus infection in type 2 diabetes (T2

293 virus-triggered IFN-I production and reduced susceptibility to virus.

294 Susceptibility to VT/VF (ventricular tachycardia/fibrill

295 phenotype and characterizing the individual susceptibility to weight change.

296 considerable inter-individual variability in susceptibility to weight gain despite an equally obesoge

297 xibility) may be informative of individuals' susceptibility to weight gain.

298 ls are efficient techniques for mapping land susceptibility to wind erosion hazards.

299 Individuals vary in aggressiveness and susceptibility to winner-loser effects but the relations

300 Interestingly, susceptibility to ZIKV clinical infection including weig