ライフサイエンスコーパス: switch

1 nthetase represents a prominent part of this switch.

2 neurons, thus forming a bipartite flip-flop switch.

3 ukin-15, and inducible caspase 9 as a safety switch.

4 ne (O-GlcNAc), in NSCs promotes a glial fate switch.

5 h structures as an important gene regulatory switch.

6 (95% CI: 0.49, 0.69) times, compared with no switch.

7 lates with a delay in the GABAergic response switch.

8 There were no deaths or study drug switches.

9 linear responses, and long-lasting molecular switches.

10 dithienylethenes, a major class of molecular switches.

11 racteristic log-normal pattern of perceptual switches.

12 ngle charge-transfer process for the reverse switching.

13 a recombinogenic process involving template switching.

14 ith temperature-dependent thermal emissivity switching.

15 ndscape topography and the kinetics of state switching.

16 than in previously demonstrated all-optical switching.

17 revealing putative sites for conformational switching.

18 mechanism of bias-induced redox-driven color switching.

19 d stable changes in the Seebeck coefficient, switching a poor nonconventional p-type thermoelectric m

20 Some gap filling occurs via template switching, a process that generates recombination-like b

21 spline models with a single knot at time of switch accounted for nonlinear trends.

22 t intermediate-sized herbivores (100-550 kg) switch activity to hotter times of the day when exposed

23 We propose that this molecular switch acts to drive progressive cell commitment, remode

24 onths before and 6-18 months after the INSTI switch/add in SWAD participants, with comparable measure

25 ve to this difference, including more choice switches after fundamental changes versus stochastic flu

26 enual anterior cingulate cortex (sgACC), and switching after harming others was associated with stron

27 Starting or switching all men and women to DTG would lead to a susta

28 The use of short columns and direct solvent switches allowed for fast screening (3 min per polarity)

29 to furl, which moves the E and F-helices and switches an electron transfer gate formed by LysF7, GlnE

30 ivation of Akt in G(1) phase causes an early switch and inhibits DNA replication.

31 lly a rearrangement of a noncanonical toggle switch and the opening of the intracellular crevice for

32 te concentration, couples the conformational switch and the phosphorylation step, resulting in the ra

33 activation of B cells is essential for class switching and contributes to the induction of B effector

34 eased expression of genes related with class-switching and memory B cell development, including Aicda

35 can cooperatively amplify the effect of the switching and obtain photocontrol of polymer length.

36 e an atomistic understanding of non-volatile switching and open a new direction in precision defect e

37 ll subsets play in clonal expansion, isotype switching, and memory B cell differentiation in response

38 neling magnetoresistance, the magnetic field switching, and the current-induced switching before and

39 that transuterine microinjection of a splice-switching antisense oligonucleotide (ASO) into the amnio

40 Splice-switching antisense oligonucleotides (ASOs), which bind

41 This angiogenic switching appears to be caused by myeloid-derived suppre

42 Autonomous switches are key elements for improving the harvested en

43 r among participants who switched or did not switch at the end of study monitoring.

44 emains operational and capable of memristive switching at temperatures as high as 300 degrees C in am

45 ction of IL-21, a cytokine crucial for class-switched B cell antibodies.

46 nly two of the three reactors experiencing a switch back from high to low F:M-C:N recovered the nitri

47 t defect concentration, yielding predictable switching because the statistical ensemble behavior of o

48 tic field switching, and the current-induced switching before and after irradiation.

49 Switching behavior persists from 15 K up to room tempera

50 ment 1, we established the baseline decision switching behavior: participants switched more frequentl

51 emonstrating flexible memristors with stable switching behaviors after repeated mechanical bending as

52 Typical 2-Cys peroxiredoxins are known to switch between different oligomeric states, depending on

53 The mechanisms controlling this bistable switch between non-active and transfer competent cells h

54 Depending on length, a flagellum can switch between these regimes.

55 membrane of the vesicles can be transiently switched between an impermeable and a semipermeable stat

56 stem, the active center can be alternatively switched between Pt species and LiCoO(2) for hydrogen ev

57 during organ evolution including expression switches between cell types.

58 long infection, the Epstein-Barr virus (EBV) switches between four viral genome latency and lytic pro

59 nnot commit to a single percept; instead, it switches between mutually exclusive interpretations ever

60 uce a naphthoquinone-based diarylethene that switches between open and closed forms with visible ligh

61 gy and exhibits reversible dynamic behavior, switching between a small-pore (sp) structure and a larg

62 ize an extended range of chemicals by simple switching between DESI, voltage-free EASI, or LTP ioniza

63 Now, an unparalleled example of switching between homolytic and heterolytic HER mechanis

64 odification activities to promote epigenetic switching between opposing chromatin states.

65 TEMENT Everyday life requires flexibility in switching between several rules.

66 theta power and synchronization for flexibly switching between task rule modules, as is useful, for e

67 Switching between these two spatial coding modes was sup

68 ortex and insula may play important roles in switching between these VPFC and DPFC systems, which may

69 gnature of a single-molecule electret is the switching between two electric dipole states by an exter

70 report the observation of a gate-controlled switching between two electronic states in Gd@C(82).

71 vice, digital information is encoded through switching between two isomer states by applying a voltag

72 Use of viral vectors to override transmitter switching blocks the beneficial effect of running on mot

73 nowledge of IGF-1's role as a novel fibrotic-switch, bringing us one step closer to understanding the

74 TP regulation in the spindle is not simply a switch, but rather generates effector gradients where im

75 genetic background as a results of serotype switching, but the drivers of these patterns are not wel

76 st that Prdm8 regulates the motor neuron-OPC switch by controlling the level of Shh activity in pMN p

77 Resistive switching can be achieved in a Mott insulator by applyin

78 t sinusoidal endothelial cell-cell contacts, switching capillaries from branching to cavernous expans

79 MFIM and MFIS stacks and their polarization switching characteristics.

80 profoundly reduces metastatic outgrowth and switches clusters from a proliferative to a collective m

81 binding of CheY proteins to the cytoplasmic switch complex of the flagellar motor, resulting in chan

82 These results suggest that switches comprising Cdk9 and either PP4 or PP1 govern pa

83 thus largely accounts for the observed lower switching contrast as compared to that of IrisFP.

84 Ripretinib is a novel switch-control kinase inhibitor designed to inhibit a wi

85 Therefore, identifying the genetic switches controlling the NLS organogenesis program in cr

86 3) with no sign of degradation after ~10(10) switching cycles.

87 However, current ovonic threshold switching devices rely heavily on intricate control of m

88 rinsic functions to moderately enhance class-switch DNA recombination (CSR), while decreasing at high

89 nstrating 100% spatially homogeneous current switching (driven by molecular redox) in memristors base

90 access memory (RRAM) suffers from stochastic switching due to the random kinetic motion of discrete d

91 ermore, TCF1 regulates the Satb1 P2 promoter switch during CD4SP development, via direct binding to t

92 l that dERR contributes to a transcriptional switch during pupal development that establishes the met

93 ic regression by comparing the occurrence of switching during the 30-day window immediately preceding

94 comprehensively characterized splice isoform switching during the transition between mesenchymal and

95 ptor switch region correlates with the class switch efficiency, raising the possibility that the mini

96 all GTPases are guanine-nucleotide-dependent switches essential for numerous cellular processes.

97 phosphatase PP2A-B55 functions as a bistable switch, even when the bistability of Cdk1 activation is

98 trol such as the use of inducer molecules or switching fermentation/environmental conditions.

99 NA cleavage and dissociation acts as an 'off-switch' for the cyclase activity.

100 f forces across the microtubule, kinesin can switch from a fast detaching motor (median attachment du

101 at increasing feedback information induced a switch from absolute to relative coding.

102 Interestingly, the trigger for lesion status switch from active to inactive can originate from an una

103 e of these coronaviruses as well as the host switch from animals to humans.

104 ical changes that permit the pneumococcus to switch from asymptomatic coloniser to invasive pathogen.

105 otonatable groups, in particular, those that switch from buried to exposed and alter protonation stat

106 The switch from centrosomal microtubule-organizing centers (

107 Importantly, parasites switch from COQ-2a to COQ-2e as they transit into anaero

108 ditions to the core STING scaffold enabled a switch from direct effector function to regulation of an

109 Neuronal GABAergic responses switch from excitatory to inhibitory at an early postnat

110 The GABA response switch from excitatory to inhibitory is a key event in n

111 We show that synapses can switch from glycolytic to oxidative metabolism, but to d

112 Of particular interest is the switch from heterotrophic to photoautotrophic seedling g

113 At 6 Ma, a striking switch from in-phase to anti-phase behaviour occurs, sig

114 Loss of NL interactions coincides with a switch from late to early replication timing, but the la

115 ransitions were characterized by a metabolic switch from lipid to glucose utilization, orchestrated b

116 wer motor neurons resulting from a premature switch from motor neuron to OPC production.

117 How pMN progenitors switch from producing motor neurons to OPCs with distinc

118 eatment induced an ALK1-dependent phenotypic switch from synthetic to contractile in pulmonary VSMCs.

119 We previously showed the switch from UQ to RQ synthesis is driven by a change of

120 myenteric neurons increased after mice were switched from ampicillin to plain water, with increased

121 In response to inflammation, MDS HSPCs switched from canonical to noncanonical NF-kappaB signal

122 those with intermediate decay-rate constants switched from reaction limitation to transport limitatio

123 hen the CoM is explicitly and systematically switched from side to side.

124 R prior to and during the process where gp41 switches from a pre-hairpin intermediate to its post-fus

125 he dependency of Q on protomer concentration switches from being dominated by a first order to a seco

126 Switching from a higher to a lower nicotine concentratio

127 rather than virulent dynamics, with viruses switching from a long-term non-lethal temperate phase in

128 nts a highly plastic compartment, capable of switching from a quiescent to an active proliferative st

129 The response regulator CheY increased motor switching from counterclockwise (CCW) to clockwise (CW)

130 Switching from diamine to ethereal ligands inverts the s

131 Compared with patients switching from placebo, earlier and continuous ocrelizum

132 Switching from single column to multiple parallel column

133 ndergo ultrarapid, isochoric, and reversible switching from soft hydrogels to rigid plastics at eleva

134 as a transcription factor that controls the switching from the ubiquitous SAG1 to rare surface antig

135 rom healthy to tumor tissue may explain AMPK switching from tumor suppressor to activator during tumo

136 ing object during self-motion, while monkeys switched, from trial to trial, between reporting object

137 The ability to switch fuels for oxidation in response to changes in mac

138 eep Neural Networks (DNN) to predict toehold switch function as a canonical riboswitch model in synth

139 demonstrate light- and cellular stress-gated switch function in cultured hippocampal neurons.

140 cell subset that contributes to IgG4 isotype switching have both been defined by multiple groups.

141 While recent advances in resistive switching have provided a path to emulate synapses at th

142 In particular, microbes can switch hierarchically between different energy sources,

143 or interfaces: (i) beta-interface, mapped to Switch I and effector-binding regions, (ii) alpha-interf

144 troduced a mutation (S217A) in the conserved switch I region of the active site to examine how myosin

145 A binds to the exposed Galpha beta sheet and switch II to stabilize the nucleotide-free state of Galp

146 known organic receptors allows the molecular switches implemented within their structures to transfor

147 ncluding activation of an immune response, a switch in cell metabolism and processes related to muscl

148 This light-dependent switch in how V1 processes head movements is controlled

149 s were sufficient to activate the angiogenic switch in lymph nodes.

150 ollowing proteasome inhibition, suggesting a switch in NUB1 function from targeted proteasomal degrad

151 xpression of KCC2, thereby delaying the GABA switch in pups of both sexes.

152 nal changes and this manifests in a profound switch in specificity towards S29 TopoIIalpha phosphoryl

153 tions of small aldehydes gives an unexpected switch in stereopreference, leading to formation of the

154 cule, and instead were driven by a metabolic switch in Th17 cells that led to the induction of the am

155 Each switch in the device consists of a silicon nitride waveg

156 This study thus reveals a light-dependent switch in the response of V1 to head movements and ident

157 o be a useful indicator of the C(4)-CAM-C(4) switches in all genotypes.

158 The incorporation of molecular switches in organic structures is of great interest in t

159 Here, we demonstrate current-induced switching in a polycrystalline PtMn/Pt metallic heterost

160 an excellent top electrode for ferroelectric switching in BiFeO(3) with no sign of degradation after

161 ting to characterize a nanoscopic picture of switching in molecular films show random current spikes,

162 cell adhesion genes and p120-catenin isoform switching in SW480 colon cancer cells: fl-APC increased

163 r, we observed changes suggesting angiogenic switching in the mouse lungs prior to arrival of tumor c

164 unable system wherein a HO...pai interaction switches incrementally to a nonconventional OH...pai hyd

165 can reconstruct the mechanism of azobenzene switching inside the cage cavity and explore key molecul

166 ese results suggest that CDKA1 may promote a switch into a division-competent state, and E2F/Dp1 may

167 Here we describe a molecular switch involving a highly conserved anion binding site i

168 an improved setup, named the extended field switching ion shutter.

169 the incidence rate of flare events with the switch (IRR: 1.04; 95% CI: 0.36-2.98; P = 0.95).

170 Strikingly, this behavioral switch is directly attributable to misregulation of homo

171 We show that inter-family and -genus switching is most common in Rhinolophidae and the genus

172 2 during early erythropoiesis and hemoglobin switching is unclear.

173 n, enabled by a halogen bond donor molecular switch, is unprecedented.

174 Accordingly, the ema ligand has switched its coordination mode from an N(2) S(2) (4-) ca

175 This switch-like accumulation period temporally coincides wit

176 ctivated at defined times and locations in a switch-like manner.

177 Mode switching likely provides a general strategy to optimize

178 onal stimulation, and a relation between the switching magnitude and the applied wavelength is depict

179 bstantial advances in non-volatile resistive switching materials such as metal oxides and solid elect

180 rminal selector preventing a transcriptional switch may constitute a general principle for safeguardi

181 size adherence counseling while delaying ART switch may promote drug resistance and should be reconsi

182 e analysis also suggests that conformational switching may modulate the assembly of CD81-partner prot

183 , which appears to act as a biased signaling switch, may predispose the AT1R and certain other GPCRs

184 Here we elucidate the origin of the switching mechanism in atomic sheets using monolayer MoS

185 In tumor tissues, mitochondria can switch metabolic phenotypes to meet the challenges of hi

186 Switching mice to a high lysine/low PN diet led to vigor

187 157 abrogated neuronal induction of IFNbeta, switched microglial polarization to M2 phenotype, preven

188 ne decision switching behavior: participants switched more frequently following incorrect trials than

189 ed MSCs to inflammatory stimuli reproducibly switched MSC secreted factor profiles and altered microv

190 s of magnitude lower than those required for switching nonlayered metallic ferromagnets such as CoFeB

191 al infection is to promote appropriate class switching, not lineage specification.

192 600 km apart), whereas in eastern Russia the switch occurred a little later (~85 Ma).

193 This glia-to-neuron cell fate switch occurs during male sexual maturation under the ce

194 e entire male GSC lineage: the most dramatic switch occurs from early to late spermatocyte, followed

195 % male and 50% nonwhite with a median age at switch of 50 years, CD4+ T-cell count 512 cells/muL, and

196 The developmental switch of NMDARs from GluN2B-containing early in develop

197 n is regulated, we studied the developmental switch of response to the neurotransmitter GABA, from ex

198 We observe reversible, bias-induced switching of conductance via a blue copper protein azuri

199 ent densities required for spin-orbit torque switching of Cr(2) Ge(2) Te(6) are about two orders of m

200 Here we report switching of fibroblast subtypes from a neonatal to adul

201 e conformational changes associated with the switching of genomic compartments observed in human cell

202 n as pH sensors required for light-dependent switching of heteromeric ACCase activity.

203 Moreover, the electrical switching of magnetic anisotropy is repeatable and non-v

204 a positive feedback and bistable collective switching of Rab5.

205 This targeted delivery improves phenotype switching of TAMs from pro- towards anti-tumor expressio

206 ut 8% contraction of the lattice spacing and switching of the intercalated ions.

207 show how differences in the electronic state-switching of the wave packet in i-C(3)H(7)I and t-C(4)H(

208 permanently switched on by neuronal spiking, switched off by strong hyperpolarization, and remain in

209 Consequently, clusters are permanently switched on by neuronal spiking, switched off by strong

210 uch as in response to self-antigens, and are switched on by tumor necrosis factor receptor 2 (TNFR2).

211 on creates an anionic cyclopentadienyl unit, switches on conjugation, leads to a >200 nm red-shift in

212 which turns off Nrf2-mediated defense while switching on an Nrf2-operated pathological program towar

213 The DVA was similar among participants who switched or did not switch at the end of study monitorin

214 boundaries in the conventional magnetization-switching paradigm of pinning-type magnets, suggesting a

215 The switching parameters and device performance of memristor

216 sion of particular invasion-related genes in switched parasites, as well as a large number of genes e

217 Mental switching performance was impaired 7% (IQR = 0-19) after

218 tions of HCs since daughter HCs are known to switch positions with each other.

219 An actin-ring segment switching process then occurs by fusion of actin fibers

220 cular factors that influence and control the switching process under realistic conditions and within

221 ession of the replication/lytic/reactivation switch protein on to enter the replicative phase.

222 We suggest that neurotransmitter switching provides the basis by which sustained running

223 RNAs-including species-specific microRNA arm switching-providing differential gene regulation is also

224 double-strand breaks (DSBs) and increase VSG switching rate.

225 lity functions of 53BP1 coevolved with class switch recombination (CSR) in the immune system.

226 ctionality, somatic mutational status, class switch recombination, and oncogenic Ig translocations.

227 not act as a rigidification element but as a switch redistributing motional processes on different ti

228 ith the light-responsive Cry2-CIB blue-light switch, referred to hereafter as the CofActor, we accomp

229 mination on both DNA strands at the acceptor switch region correlates with the class switch efficienc

230 ts across the entire length of an engineered switch region in cells ablated for uracil repair.

231 apable regions (LG4s)-like those at antibody switch regions-remain virtually unexplored.

232 arge number of Cys peptides (412) were redox switched, representing central pathways of mitochondrial

233 e is increasingly well documented, and these switches require changes in the postsynaptic receptor po

234 y, defining metabolic heterogeneity and fuel-switching signals in nonneoplastic stem cells may also g

235 pective of age, adults with better attention switching skills were redundant in efficient ways, demon

236 es), while CON acted as a flexible switcher (switching specific regions to other systems to lend proc

237 f alterations in components of the mammalian switch/sucrose non-fermentable (mSWI/SNF or BAF) chromat

238 Here, we developed an ON-switch system in which the human retinol binding protein

239 ew approach for the development of molecular switching systems and storage-class memories.

240 er adults, cognitive performance on a mental switching task was slightly (7%) reduced after indometha

241 aracterize decision processing during a rule-switching task.

242 ne-protein kinase 1), which acts as a master switch that controls whether the cell undergoes NF-kappa

243 the C terminus, resulting in a cis-to-trans switch that is likely to enable protein-protein interact

244 h pH and ionic strength controlled molecular switch that regulated HUalphaalpha dependent intermolecu

245 CeA Crh neurons, may function as a molecular switch that regulates expression of fear and its extinct

246 ork is G3BP1, which functions as a molecular switch that triggers RNA-dependent LLPS in response to a

247 type III hammerhead ribozymes to develop RNA switches that are highly efficient at cis-cleaving mamma

248 Here, we define two kinase-phosphatase switches that operate at different points in human trans

249 he Rab family of small GTPases are molecular switches that regulate distinct steps in different membr

250 ciated mechanism underlying human hemoglobin switching that illuminates new therapeutic opportunities

251 rther demonstrate how the charge current can switch the magnetization of the ferromagnetic TBG near 3

252 tions of mGluR5 with estrogen receptors that switch the normally positive effects of estrogen on SF1

253 The ability of neurons to switch the transmitter they release is increasingly well

254 and requires HPF1, an accessory factor that switches the amino acid specificity of PARP1 and PARP2 f

255 between resistant and sensitive viruses also switches the G3BP deletion sensitivity.

256 Switching the energy scan mechanism from a mechanical mo

257 bending of the actuator can be controlled by switching the laser polarization.

258 The shorter the delay in switching, the lower the hazard of death-delaying 30-59

259 selected image during inaccurate trials and switched their gaze between response options more freque

260 re at this time, and the recommendations for switching therapies for convenience and for other reason

261 V-CTLs restricted by a different HLA allele (switch therapy) can also induce remissions if initial EB

262 Switching therapy for virological failure is relatively

263 y polarized beam lasing, or vice versa, with switching times of 1 to 1.5 picoseconds and energy consu

264 sm to be awake and active(4), the ability to switch to a memory consolidation mechanism that is not c

265 The switch to an asthenospheric magma source at ~107 Ma occu

266 a9 helix (C175) of BFL-1 operates as a redox switch to control the accessibility of the anti-apoptoti

267 t rely on the ability to undergo a metabolic switch to glycolysis to allow them to perform rapid plas

268 is cell plasticity-the ability of a cell to switch to new identities.

269 Thereafter, a phenotypic switch to oxidative metabolism with lipid utilization to

270 BFD1 provides a genetic switch to study and control Toxoplasma differentiation a

271 that the MAPK signaling pathway is a general switch to trans-regulate differential expression of amin

272 The switch to WHO-recommended dolutegravir (DTG)-based regim

273 he SRAs for the children's weight band; then switched to 50 mg film-coated tablets once daily.

274 e not switched to another TKI or if they are switched to a inappropriate TKI or TKI dose.

275 invariably selected if the patients are not switched to another TKI or if they are switched to a ina

276 nd those on NNRTI-based regimens are rapidly switched to DTG.

277 The 972 participants who switched to INSTIs were 81% male and 50% nonwhite with a

278 we reveal that the vortex beam lasing can be switched to linearly polarized beam lasing, or vice vers

279 markable effect, improved when treatment was switched to mepolizumab.

280 dose or standard anticoagulants (heparin or switched to vitamin K antagonist).

281 requency pulses, along with diodes acting as switches to control the resonance frequency of the reson

282 rd combination antiretroviral therapy (cART) switching to DTG + emtricitabine (FTC).

283 ith remarkable antitumor activity by isotype switching to hIgG2.

284 patients (66.7%) who experienced flare after switching to infliximab-abda did so within 90 days.

285 ing an exclusively light-triggered resistive switching to memristive devices irrespectively of the st

286 ed ART delivery by 25 percentage points, and switching to second-line ART by 1 percentage point compa

287 85B epitope and consistently induced isotype switching to the IgG2c subclass.

288 sion in U. maydis, which serves as a "toggle switch" to control the fungal decision between infecting

289 es (completers, noncompleters, and those who switched treatment ).

290 considered as unsuitable for pure electrical switches; under weak electric fields, they show extremel

291 d soluble proteins into allosteric molecular switches useful in biodesign, sensing, and synthetic bio

292 l-behaved integrated logic circuits with low switching voltages compatible with standard CMOS electro

293 D) array of surface-mounted azobenzene-based switches was detected for the first time.

294 Using inducible genetic switches, we demonstrate that swimming motility can be m

295 idfrontal theta power was stronger when rule switches were most likely (strong negative prediction er

296 Anti-VEGF injection rates and treatment switches were not important factors in determining visua

297 Generated MDSCs displayed a glycolytic switch, which rendered them more susceptible toward glyc

298 limited in part by the lack of small genetic switches with wide dynamic ranges that control transgene

299 We thus reveal a "phospho-switch" within delta-catenin, subject to a glutamate-med

300 illumination ultimately results to resistive switching, without involving any additional stimulation,