ライフサイエンスコーパス: synaptic contact

1 on of axons into nerve terminals at sites of synaptic contact.

2 ty of dendritic spines and the potential for synaptic contact.

3 ptic vesicles, PSA is lost from the point of synaptic contact.

4 the symmetry and stability of the T cell-APC synaptic contact.

5 racellular proteins are targeted to sites of synaptic contact.

6 uration of Purkinje neurons and formation of synaptic contacts.

7 xon-to-soma transfer appeared not to require synaptic contacts.

8 d retinal function, it did not restore these synaptic contacts.

9 croarray criteria, and could form functional synaptic contacts.

10 g growth cone migration and the formation of synaptic contacts.

11 y dendritic spines initially lack functional synaptic contacts.

12 hat indirectly affect junctional coupling at synaptic contacts.

13 s experienced an increase in their number of synaptic contacts.

14 l types participate in a single 2D mosaic of synaptic contacts.

15 ose appositions by OT fibers consistent with synaptic contacts.

16 th LTD induction is capable of restructuring synaptic contacts.

17 ant mice are unmyelinated and maintain their synaptic contacts.

18 s confer functionality on existing nicotinic synaptic contacts.

19 ation of the dendritic field and appropriate synaptic contacts.

20 uning but not translocation of nascent CF-PC synaptic contacts.

21 on of synaptic efficacy and formation of new synaptic contacts.

22 ns, and form extensive reciprocal excitatory synaptic contacts.

23 und that axon arbor dynamics are affected by synaptic contacts.

24 subbarrels denote barrel regions enriched in synaptic contacts.

25 alization of the dopamine signal to specific synaptic contacts.

26 ifferently, depending on the location of the synaptic contacts.

27 to mediate the formation of new axodendritic synaptic contacts.

28 about the function of these early en passant synaptic contacts.

29 ith extending motor axons through en passant synaptic contacts.

30 nes continue to be dynamic even if they bear synaptic contacts.

31 itude and a larger increase in the number of synaptic contacts.

32 get bipolar cell via triad-associated (flat) synaptic contacts.

33 ed with axons and particularly enriched near synaptic contacts.

34 structure with open "holes" at the sites of synaptic contacts.

35 s is not necessarily associated with loss of synaptic contacts.

36 e, causing the constant replacement of their synaptic contacts.

37 crine in nature, due to the apparent lack of synaptic contacts.

38 and thereby support long-term plasticity of synaptic contacts.

39 ence of Cx36 led to an increase in GABAergic synaptic contacts.

40 nition specificity is important to establish synaptic contacts.

41 ng dendrites and send signals along axons to synaptic contacts.

42 types and establishes the original number of synaptic contacts.

43 external tufted cells was the result of more synaptic contacts.

44 tion, retraction and/or stabilization of new synaptic contacts.

45 ability to segment neurites and to identify synaptic contacts.

46 synaptic transmission and differentiation of synaptic contacts.

47 C classes, constituting 5%-25% of all axonal synaptic contacts.

48 ient spines may serve to produce short-lived synaptic contacts.

49 ning the levels of cAMP within the GABAergic synaptic contacts, activated group II mGluRs prevent the

50 ed neuromuscular activity through en passant synaptic contacts affects pre- and postsynaptic developm

51 eous long-term (bidirectional) modulation of synaptic contacts along the same basal branch.

52 Pcdhg(tcko/tcko)) showed plenty of GABAergic synaptic contacts, although their density was reduced co

53 inferring neuron type circuitry, predicting synaptic contacts among individual cells, and estimating

54 CD4 T cells that maintained a synaptic contact and appeared to be responsible for VSMC

55 The area of synaptic contact and extent of post-synaptic folding wer

56 at translation was enriched only at sites of synaptic contact and/or synaptic stimulation.

57 Mushroom spines form strong synaptic contacts and are essential for memory storage.

58 ADDLs bind rapidly and with high affinity to synaptic contacts and cellular membranes.

59 atterns to compensate for the variability of synaptic contacts and help ensure appropriate connectivi

60 taining for KA1 and KA2 was commonly seen at synaptic contacts and in vesicular structures.

61 at MeCP2 may be involved in the formation of synaptic contacts and may function in activity-dependent

62 ection algorithm to identify cell membranes, synaptic contacts and mitochondria.

63 mber of spine protrusions (that is, sites of synaptic contacts) and block long-term synaptic potentia

64 which involves a reduction in the density of synaptic contacts, and an increased proportion of orphan

65 d with synapse formation, the maintenance of synaptic contacts, and the specific distribution of mRNA

66 New synaptic contacts appear in the neuropil where the gaps

67 postsynaptic membranes at this large area of synaptic contact are kept at a remarkably regular distan

68 o models persists even when large numbers of synaptic contacts are considered.

69 In cima-1 mutants, synaptic contacts are correctly established during embry

70 es and the number of anatomically identified synaptic contacts are equal at connections between spiny

71 Because the majority of synaptic contacts are formed on dendrites, the structura

72 the neuronal processes, on which excitatory synaptic contacts are formed, and the loss of dendritic

73 Synaptic contacts are largely established during embryog

74 the intrinsic photoresponse, suggesting that synaptic contacts are made onto the entire dendritic fie

75 antia nigra pars compacta (SNc) where direct synaptic contacts are made with both dopaminergic and no

76 ritic tree of neurons, where the majority of synaptic contacts are made, there has not been an experi

77 lls, the number, morphology, and function of synaptic contacts are profoundly altered, resulting in a

78 on of SP neurons, suggesting that functional synaptic contacts are rare at midgestation.

79 period may be accompanied by a reduction of synaptic contacts, as well as a reorganization of postsy

80 afferent fibres make their first excitatory synaptic contact at second-order NTS neurones with gluta

81 To visualize synaptic contacts at the ultrastructural level, we devel

82 ransmission at the motor endplate, a special synaptic contact between motor axons and each skeletal m

83 e now demonstrate the presence of functional synaptic contacts between ascending axons (aa) of GrCs a

84 of these muscle responses indicate that the synaptic contacts between ascending sensory fibres and m

85 al network, and the numerical proportions of synaptic contacts between calycal neurons.

86 pelling evidence for the existence of direct synaptic contacts between CFs and NG2-expressing glia ce

87 Approximately 65% of identified synaptic contacts between DbH- and PRV-positive profiles

88 uide axons into a channel, thus facilitating synaptic contacts between neurons originating from oppos

89 We also found synaptic contacts between retinal terminals and TGC dend

90 Synaptic contacts between taste cells and nerve processe

91 ted dLGN activity may be enhanced via direct synaptic contacts between thalamocortical cells, whereas

92 We also discovered synaptic contacts between the putative OSNs.

93 The initial establishment of synaptic contacts between these identified neurons is se

94 y function independently in the formation of synaptic contacts, but act together to recruit syntenin-

95 ve means to recognize and measure individual synaptic contacts, but EM has only limited abilities to

96 number of mushroom spines-all of which make synaptic contacts-but not in the numbers of filopodia or

97 os expression in host neurons, indicative of synaptic contact by regenerating fibers.

98 mination is well studied and events at every synaptic contact can be examined.

99 Elimination of the excess synaptic contacts established in the early stages of neu

100 Putative synaptic contacts evident as bouton-like varicosities we

101 cture of the inhibitory nerve terminals near synaptic contacts examined with thin-serial-section elec

102 TH-ir terminals rarely formed clear synaptic contacts, except for a few that established asy

103 channels that shape receptor potential, and synaptic contacts for conveying information centrally.

104 We show that as the first en passant synaptic contacts form, excessive postsynaptic activity

105 icate that the structural role of GABAARs in synaptic contact formation is determined by their subuni

106 bition leads to an increase in the number of synaptic contacts formed between the sensory and motor n

107 tials to link GABA release at many different synaptic contacts formed with principal cells.

108 connection, consistent with there being more synaptic contacts formed.

109 nd order neurones in the retina that receive synaptic contact from cones and not from rods.

110 the somas and 50% of the dendrites received synaptic contact from GABA immunoreactive terminals in b

111 Hypocretin neurons received direct synaptic contact from other hypocretin neurons but showe

112 ve fibers preferentially contact and receive synaptic contact from Type III taste cells.

113 ion confocal microscopy to identify putative synaptic contacts from afferent fibers of the two nerves

114 input to abDGCs by increasing the number of synaptic contacts from both interneuron types.

115 We show here that synaptic contacts from dorsal root ganglions to a small

116 Putative synaptic contacts from each nerve are often compartmenta

117 The finding that these cells receive synaptic contacts from excitatory and inhibitory neurons

118 antly, the number and strength of inhibitory synaptic contacts from FS (PV) INs onto principle neuron

119 field potentials were recorded from CA3-CA1 synaptic contacts from hippocampal slices obtained from

120 Spatially synaptic contacts from L1 INs target distal apical tuft

121 on of PFC pyramidal neurons receiving direct synaptic contacts from midbrain dopaminergic neurons wou

122 cell GRASP analyses reveal that Li4 receives synaptic contacts from over 90% of all four types of chr

123 hypothesis that a decrease in the number of synaptic contacts from PH-SNs to APRs contributes to thi

124 from vulnerable alpha-MNs in that they lack synaptic contacts from primary afferent (IA) fibers.

125 Synaptic contacts from processes immunoreactive for glut

126 dent rod-cone coupling, but rather by direct synaptic contacts from rods and M-cones.

127 pic examination of bNOS-labeled cells showed synaptic contacts from terminals with two distinct morph

128 t between LTP and LTD as the distance of the synaptic contacts from the soma increases.

129 Presynaptic terminals of incipient synaptic contacts generate calcium transients in respons

130 By virtue of their synaptic contacts, glycine centrifugal feedback increase

131 se that, although NG2(+) progenitors receive synaptic contact in all brain regions where they are fou

132 Nevertheless, direct synaptic contact in deep layers 5 and 6 may provide a mo

133 aordinarily, the RBC axons showed additional synaptic contacts in a second sublamina further out in t

134 ally regulated manner, in order to establish synaptic contacts in a two-step process.

135 onnections were mediated on average by three synaptic contacts in both species.

136 GRASP marks known synaptic contacts in C. elegans, correctly identifies ch

137 mechanisms that can lead to the addition of synaptic contacts in developing neurons and changes in t

138 roportion of excitatory immature symmetrical synaptic contacts in MAP1B KO neurons was detected.

139 Nlgns) are adhesion proteins mediating trans-synaptic contacts in neurons.

140 ly to the CNS via conventional glutamatergic synaptic contacts in olfactory bulb glomeruli.

141 hundreds of neighbouring axons and multiple synaptic contacts in one small volume of a cerebellar lo

142 ulate sympathetic and autonomic activity via synaptic contacts in the RTN, NTS, and RVLM and provides

143 o show that visual CST axon collaterals form synaptic contacts in the spinal cord before pruning and

144 Because the number of synaptic contacts involved is not known, the response co

145 n of ELFN1 in mice prevents the formation of synaptic contacts involving rods, but not cones, allowin

146 that the amount of transmitter released per synaptic contact is independent of release probability a

147 The loss of synaptic contacts is associated with the formation of re

148 studies, whereas ultrastructural evidence of synaptic contacts is scarce.

149 We observed the following distribution of synaptic contacts: large terminals that contain loosely

150 e compared between sham and injured animals; synaptic contact length was also measured.

151 es retinal function but does not reestablish synaptic contacts lost by chronic hypoglycemia.

152 particles were present in close proximity to synaptic contacts (<0.5 mum from the postsynaptic densit

153 Synaptic contacts made by recorded NGFCs showed close ap

154 lattice light-sheet and quantum dot-enabled synaptic contact mapping microscopy to show that anomalo

155 ity support the idea that plastic changes of synaptic contacts may depend at least in part on IkappaB

156 Interneurons with anatomically identified synaptic contacts migrate from the outer to the inner re

157 boutons (MSBs), and boutons with no apparent synaptic contacts [nonsynaptic boutons (NSBs)] in the OM

158 solitarii (NTS), the first central site for synaptic contact of the lung and airway afferent fibres.

159 t and mouse brain and the different sites of synaptic contact of the synapses from the three GABAergi

160 a more refined examination of the potential synaptic contacts of aminergic systems.

161 ction was used to reveal the distribution of synaptic contacts of different types on the afferent ter

162 into the cerebellar cortex, where they make synaptic contacts on a GABAergic subpopulation of cerebe

163 Anatomical studies have described inhibitory synaptic contacts on apical dendrites, and an abundant n

164 d PHA-L (+)/VGluT2 (+) axon terminals formed synaptic contacts on dendrites of both TH-positive and T

165 hich the CA3 pyramidal cells make excitatory synaptic contacts on each other.

166 When present, however, synaptic contacts on GABAergic profiles were observed mo

167 ited by the brain via activation of efferent synaptic contacts on hair cells.

168 The distribution of synaptic contacts on interneurons was as follows: RL pro

169 Consistent with this, we observed synaptic contacts on L-ITCc dendrites from nociceptive i

170 ely packed with vesicles and make asymmetric synaptic contacts on low-order dendrites of VMpo neurons

171 dendritic shafts and spines to characterize synaptic contacts on MePD neurons of both hemispheres in

172 receptor 1 subunit, and decreased inhibitory synaptic contacts on POMC neurons.

173 T-stellate cells, and made local inhibitory synaptic contacts on principal cells of the VCN.

174 ns arise from the neural crest and establish synaptic contacts on smooth and striate muscle in the ey

175 ation of the afferent terminals reveals that synaptic contacts on terminal branches are particularly

176 The distribution of synaptic contacts on thalamocortical cells was as follow

177 of axons from layer III EC neurons that make synaptic contacts on the distal dendrites of CA1 neurons

178 nsmission at mixed (electrical and chemical) synaptic contacts on the goldfish Mauthner cell.

179 Mixed (electrical and chemical) synaptic contacts on the Mauthner cells, known as Club e

180 tonergic neurons, possibly through points of synaptic contacts on the mushroom body (MB), is essentia

181 eactive terminals, whereas 3.6% received two synaptic contacts on the spine head, neck, or base.

182 to determine the nature and distribution of synaptic contacts on the terminals of rapidly adapting m

183 eurons (PNs) receive thousands of excitatory synaptic contacts on their basal dendrites.

184 up motoneurons displayed significantly fewer synaptic contacts on their somata and proximal dendrites

185 I and VAChT-LI nerve endings making putative synaptic contact onto IMG neurones and a majority of put

186 ide primarily in the selective addressing of synaptic contacts onto dendritic subunits.

187 for sustained periods in vivo, yet makes few synaptic contacts onto individual granule cells.

188 he strengthening of individual glutamatergic synaptic contacts onto layer 2/3 neurons only during a s

189 h clear, spherical vesicles, made asymmetric synaptic contacts onto motoneurons in the rostral popula

190 es in the spatial distribution of excitatory synaptic contacts onto PN basal dendritic arbors.

191 n types is the spatial distribution of their synaptic contacts onto PNs, but the location-dependent e

192 fibers running through the hippocampus forms synaptic contacts onto pyramidal cells, granule cells, a

193 e reveal that Mi1 and Tm3 cells provide most synaptic contacts onto T4.

194 pil we found single axons making two or more synaptic contacts onto the same dendrites, having shared

195 , as an increase in the number of functional synaptic contacts, or by a combination of these mechanis

196 ower frequency of MSBs and a lower number of synaptic contacts per MSB, and the latter variable inver

197 confocal microscopy, we studied rod and cone synaptic contacts, photoreceptor-bipolar cell convergenc

198 r spherical vesicles and formed asymmetrical synaptic contacts, primarily on the proximal dendrites o

199 induces significant IL-2 accumulation in the synaptic contact region.

200 man memory is thought to occur at individual synaptic contact sites and manifest as persistent change

201 rminals, and more stringently, to individual synaptic contact sites within each terminal.

202 by a more pronounced separation of CF and PF synaptic contact sites.

203 parallel to the dendrites and make multiple synaptic contacts support such coordination since incomi

204 al lateral geniculate nucleus (dLGN) through synaptic contacts terminating primarily in cortical laye

205 Dendritic spines are sources of synaptic contact that can be altered by experience and,

206 lecular layer, spiny hilar interneurons form synaptic contacts that appear to be positioned to exert

207 n of hundreds of uniformly sized, individual synaptic contacts that are labeled with neurexin antibod

208 sts a mechanism for the formation of ectopic synaptic contacts that is driven by the retraction of ro

209 c protrusions; and (iii) decreased GABAergic synaptic contacts that these neurons receive.

210 ut from RCs results from the large number of synaptic contacts that they make onto individual motoneu

211 y-nine percent of boutons received axoaxonic synaptic contacts, the mean number of contacts per bouto

212 al tracing and volumetric reconstructions of synaptic contacts, this shows that the multifunctional p

213 iating formation and elimination of specific synaptic contacts through competition-based mechanisms.

214 ines the set of axons with which it may form synaptic contacts, thus establishing connectivity within

215 s after injury requires the formation of new synaptic contacts to enable functional recovery.

216 neuromuscular junctions, and they make fewer synaptic contacts to the postsynaptic muscle membrane, a

217 MLV-laden macrophages then form long-lived synaptic contacts to trans-infect B-1 cells.

218 action-potential firing to attract and keep synaptic contacts, to drive gene expression, and to tran

219 Synaptic contacts undergo a maturational transformation

220 Thus, the quantal content per unit area of synaptic contact was normal.

221 Significant remodeling of synaptic contacts was found on CRH neurons in response t

222 decreased gamma2 labeling near the center of synaptic contacts was paralleled by a corresponding decr

223 axo-spinous to axo-dendritic corticostriatal synaptic contacts was reduced.

224 proposed to facilitate the formation of new synaptic contacts, we have reported that spines continue

225 Numerous sites of putative synaptic contact were found on the somata, proximal dend

226 Cocaine-mediated reductions in synaptic contact were reversed by the beta-lactam antibi

227 l excitatory as well as GABAergic inhibitory synaptic contacts were increased on CRH neurons; however

228 c structures showed that essentially all new synaptic contacts were made by adding new partners to ex

229 istinguished, and the size and proportion of synaptic contacts were similar to those of the adult.

230 The synaptic contacts were single or multiple, and some, but

231 ction potentials and many matured to receive synaptic contacts when co-cultured with primary mouse co

232 hibernating mammals, cooling induces loss of synaptic contacts, which are reformed on rewarming, a fo

233 nsitional forms maintain old and acquire new synaptic contacts while migrating across the dentate pla

234 ly 36% formed either a close apposition or a synaptic contact with a somatic or dendritic profile.

235 es that transform into dendritic spines upon synaptic contact with axon terminals.

236 a marker, we show that the DB1 bipolar makes synaptic contact with both L/M as well as S-cone photore

237 e of VGLUT2(+) axodendritic terminals making synaptic contact with ChAT(+) dendrites per unit area of

238 he VTA and only 15% in the SN appose or form synaptic contact with DA neurons, which support our prev

239 beled fibers, which in some cases made close synaptic contact with GAD-67-labeled NI neurons.

240 VGLUT3 processes made synaptic contact with ganglion cell dendrites, suggestin

241 ns in the VTA and were largely biased toward synaptic contact with local GABA neurons.

242 evealed CB1r-positive axon terminals forming synaptic contact with MOR-containing dendrites.

243 th rabies virus reveals that this results in synaptic contact with more presynaptic partners.

244 oreceptor cells in the mammalian retina make synaptic contact with only a single population of rod bi

245 ynaptic density (PSD) of dendritic spines in synaptic contact with parallel or climbing fibers.

246 th numerous vesicle-filled boutons that made synaptic contact with Purkinje cell spines.

247 corticostriatal neuron types made asymmetric synaptic contact with spine heads and less frequently wi

248 e immunoreactivity in axons and dendrites in synaptic contact with the afferent terminals was demonst

249 tion provides structural support to calyceal synaptic contact with the vestibular hair cell and that

250 Whether the Ipc axons make synaptic contact with these or other tectal neural eleme

251 tsynaptic excitatory neurons in rodents make synaptic contacts with >21-30% of presynaptic axons enco

252 egions, involving a decline in the number of synaptic contacts with AII amacrine cells (by 60%) and m

253 the hindbrain, DA terminals form traditional synaptic contacts with auditory efferent neuronal cell b

254 A)Rs) that are activated by GABA released at synaptic contacts with axons or by ambient GABA in extra

255 ferentiating into afferent neurons that form synaptic contacts with both epidermal sensory cells and

256 CA2 neurons in turn make strong excitatory synaptic contacts with CA1 neurons.

257 dult-born dentate granule cells form initial synaptic contacts with CA3 pyramidal cells within 2 week

258 y may influence cortical development through synaptic contacts with Cajal-Retzius (CR) cells.

259 silla along the crayfish antennules at their synaptic contacts with central nervous elements that dri

260 the bistratified A8 cell makes very similar synaptic contacts with cone bipolar cells as the rod pat

261 f horizontal interneurons, which form direct synaptic contacts with cone photoreceptors.

262 along its cholinergic axons make traditional synaptic contacts with cortical neurons.

263 LGN neurons project to layer I of V1 to form synaptic contacts with dendrites of deeper-layer neurons

264 ect collaterals to cochlear nucleus and make synaptic contacts with dendrites of multipolar neurons.

265 e dorsolateral DRN (16%; n = 251 terminals), synaptic contacts with dendrites that lacked detectable

266 itive terminals formed close appositions and synaptic contacts with dendritic and somatic compartment

267 tically involved in motor control, and makes synaptic contacts with dopaminergic neurons.

268 the PGN, we found that all RLD profiles make synaptic contacts with GABAergic PGN somata, dendrites,

269 the coincidence of sensory input at central synaptic contacts with giant fiber targets.

270 larval zebrafish, each afferent neuron forms synaptic contacts with hair cells of a common hair-bundl

271 y with misrouted afferent fibers and reduced synaptic contacts with hair cells.

272 e identified N/OFQ-containing fibers forming synaptic contacts with Hcrt neurons at both the light an

273 ive differentiation into neurons that formed synaptic contacts with host nerve cells and expressed an

274 rom the brainstem and makes transient direct synaptic contacts with inner hair cells.

275 ipRGCs form synaptic contacts with major peptidergic cells of the SC

276 Also, dopamine reduction and the loss of synaptic contacts with melanopsin cells may contribute t

277 Axons often form synaptic contacts with multiple targets by extending bra

278 rgets, migrating motor axons form en passant synaptic contacts with myotomal muscle.

279 (NCAM), suggesting that these TRCs may have synaptic contacts with nerve terminals.

280 r 5-8% of the glial cell population and form synaptic contacts with neurons.

281 d in the outer plexiform layer and preserved synaptic contacts with OFF but not with ON bipolar cells

282 c CSF-cNs retain PKD2L1-immunoreactivity and synaptic contacts with other neurons.

283 cs may be important for establishing initial synaptic contacts with postsynaptic partners, refining c

284 that estrogen-induced dendritic spines form synaptic contacts with preexisting presynaptic boutons,

285 R-like immunoreactive nerve terminals formed synaptic contacts with retrogradely labeled genioglossus

286 nob2 retina and to the formation of ectopic synaptic contacts with rod photoreceptors in the ONL.

287 n-rich protrusions that establish excitatory synaptic contacts with surrounding neurons.

288 d to become myelinated or to form functional synaptic contacts with target muscles, and a subpopulati

289 amacrine cells, S1 and S2, have stereotyped synaptic contacts with the appropriate morphology and di

290 ned spherical vesicles and formed asymmetric synaptic contacts with the labeled motoneurons.

291 basket cell axons fail to make identifiable synaptic contacts with the Purkinje cell axon.

292 aled that MOC collaterals made some putative synaptic contacts with the retrogradely labeled neurons

293 iest serotonergic projections to the MZ form synaptic contacts with the somata and proximal dendrites

294 al outflow of retinal signals through direct synaptic contacts with the TGCs.

295 type of photoreceptor, cone or rod, forming synaptic contacts with their dendrites, suggesting a pot

296 e reveal that each Dm8 neuron forms multiple synaptic contacts with Tm5c in the center of Dm8's dendr

297 the surface of the nasal epithelium and form synaptic contacts with trigeminal afferent nerve fibers.

298 from the lumbosacral cord made asymmetrical synaptic contacts with unlabeled dendrites and ER-alpha

299 By contrast, synaptic contacts within the IPL also decreased with sen

300 e, containing 379 neurons and 8,637 chemical synaptic contacts, within the Drosophila optic medulla.