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1 tured neurons, suggesting that neurexins are synaptogenic.
2 ndicating that Drosophila astrocytes are pro-synaptogenic.
3 receive, indicating that Pcdh-gammaC5 is not synaptogenic.
4 ed cells, indicating that collybistin is not synaptogenic.
5 ected by MEN1 knockdown, indicating that the synaptogenic actions of menin are specific to cholinergi
6  an assay system that permits examination of synaptogenic activities of individual cell-surface prote
7 ubule (MT) minus ends mediates pro- and anti-synaptogenic activities of presynaptic neurexin and friz
8                       Furthermore, this anti-synaptogenic activity is interchangeable with that of LI
9                                          The synaptogenic activity of APP is abolished by triple knoc
10 -beta and that neurexin is essential for the synaptogenic activity of APP.
11 ent in cultured neurons and in vivo, and the synaptogenic activity of LRRTM4 requires the presence of
12 binding to recombinant neurexins, blocks the synaptogenic activity of neuroligin-1, and reduces the d
13  model in which Narp can regulate the latent synaptogenic activity of NP1 by forming mixed pentraxin
14 affinity for GluRdeltas and exhibits greater synaptogenic activity than Cbln2.
15 eal the neurexin binding interface mediating synaptogenic activity to be composed primarily of residu
16              MDGA binding and suppression of synaptogenic activity was selective for neuroligin-2 and
17        alpha(2)delta proteins have conserved synaptogenic activity, although how they execute this fu
18 mily members (APP, APLP1, and APLP2) exhibit synaptogenic activity, involving trans-synaptic dimeriza
19 show that APP binds neurexin to mediate this synaptogenic activity.
20 hat NT-3 modulates TrkC/PTPsigma binding and synaptogenic activity.
21 ding affinity of Cb, which limits its normal synaptogenic activity.
22 differentiating neurons strongly impairs its synaptogenic activity.
23 ction.SIGNIFICANCE STATEMENT Whether and how synaptogenic adhesion at axo-dendritic contact sites reg
24        Significance statement: Although many synaptogenic adhesion complexes have been identified in
25 lly analyzing synaptic membranes lacking the synaptogenic adhesion molecule SynCAM 1.
26                                              Synaptogenic adhesion molecules play critical roles in s
27                           Given the links of synaptogenic adhesion molecules to autism and schizophre
28                         This was mediated by synaptogenic adhesion molecules, with the classical Neur
29 esults in basal synaptic deficits and blocks synaptogenic and antidepressant actions of ketamine in P
30  role of the GSK-3 pathway in modulating the synaptogenic and antidepressant responses to ketamine.
31 edial prefrontal cortex (mPFC) show that the synaptogenic and antidepressant-like effects of a single
32                      Here, we found that the synaptogenic and antidepressant-like effects of a single
33                   This pair of media are pro-synaptogenic and generate authentic, mature synaptic net
34 s the hUTC-secreted factors that mediate the synaptogenic and growth-promoting functions of these cel
35 stoma subpopulation that exhibits a distinct synaptogenic and neuronotrophic phenotype.
36                                 SPARC is not synaptogenic, but specifically antagonizes synaptogenic
37  neuronal networks to test whether predicted synaptogenic capabilities were affected by previous syna
38 y changes in knock-out (KO) mice lacking the synaptogenic cell adhesion protein SynCAM 1.
39 nctions as a glutamatergic synapse-inducing (synaptogenic) cell adhesion molecule trans-interacting w
40 these results suggest Kirrel3 functions as a synaptogenic, cell-recognition molecule, and this functi
41 th short-term data, which is indicative of a synaptogenic compensatory mechanism of the abducens inte
42  dendrites are thought to facilitate initial synaptogenic contact with axons.
43 opodia may be actively involved in mediating synaptogenic contact.
44 at dendritic filopodia may actively initiate synaptogenic contacts with nearby (5-10 micron) axons an
45 te reactivation of a single latent astrocyte synaptogenic cue alters striatal circuits controlling be
46 sponses also resulted in upregulation of the synaptogenic cue thrombospondin-1 (TSP1) in astrocytes,
47         Structural, functional and molecular synaptogenic defects are all phenocopied by Wg overexpre
48 p mutants prevents structural and functional synaptogenic defects.
49                         Mechanistically, the synaptogenic deficiency of R215H mutant was due to its r
50 the interaction involving the thrombospondin synaptogenic domain and the alpha2delta-1 von-Willebrand
51 ing the whole protein or only its C-terminal synaptogenic domain have reduced inhibitory synapse numb
52 ic rescue approaches, we discovered that the synaptogenic domain of neurocan localizes to somatostati
53 oprecipitation between alpha2delta-1 and the synaptogenic domain of thrombospondin-2 was prevented by
54 ses in glutamatergic neurons, suggesting its synaptogenic effect is specific to GABAergic interneuron
55                          In Met/Met mice the synaptogenic effect of ketamine was markedly impaired, c
56   Our results indicate that Fz5 mediates the synaptogenic effect of Wnt7a and that its localization t
57 ological inhibition, prevented the TGF-beta1 synaptogenic effect.
58 der neuronal preparations, morphogenetic and synaptogenic effects of 5-HT(7)/G(12) signaling are abol
59                                          The synaptogenic effects of SC-CM were abolished if SC-CM wa
60 r to frog SC-CM, mammalian SC-CM also showed synaptogenic effects, which were prevented by immunodepl
61 in-1 played an important role in ACM-exerted synaptogenic effects.
62 gabapentin binding was not reproduced by the synaptogenic EGF-domain of thrombospondin-4.
63 t a noncanonical function of GABA as a local synaptogenic element shaping the early establishment of
64 ously decreases the time required to capture synaptogenic events by an order of magnitude.
65 t SST(+) interneuron-derived Collagen XIX, a synaptogenic extracellular matrix protein, is required f
66     Our work identifies a novel glia-derived synaptogenic factor by which glia modulate synapse forma
67 beta1, previously identified as an important synaptogenic factor secreted by astrocytes, abrogated th
68 egulating synaptogenesis and that SRPX2 is a synaptogenic factor that plays a role in the pathogenesi
69 ts through various mechanisms, including the synaptogenic factor thrombospondin-1 (TSP-1).
70 m functionally connected regions secrete the synaptogenic factor thrombospondin-1, which contributes
71 studies have begun to identify glial-derived synaptogenic factors [1], but neuron-glia signaling even
72 ology, we identified the major hUTC-secreted synaptogenic factors as the thrombospondin family protei
73                  Although astrocyte-secreted synaptogenic factors have been identified, the molecules
74 TGF-beta1 thus joins other astrocyte-derived synaptogenic factors in further strengthening the emergi
75 HBS4 and SPARCL1, directly act on neurons as synaptogenic factors.
76 on" model, where at any time point only 1-2 "synaptogenic" filopodia suppress the synaptic competence
77                                          APP synaptogenic function depends on trans-directed dimeriza
78                                         This synaptogenic function has been conserved across evolutio
79 gous cholinergic mechanism underlies menin's synaptogenic function in the vertebrate CNS.
80 the astrocytic secretome, leading to loss of synaptogenic function in vitro.
81                                          The synaptogenic function of alpha(2)delta-3 required only t
82 t synaptogenic, but specifically antagonizes synaptogenic function of hevin.
83                        Here we demonstrate a synaptogenic function of netrin-1 in rat and mouse corti
84 eta and Nrxn3beta, consistent with a general synaptogenic function of neurexins.
85  small RNA interference, eliminated both the synaptogenic function of these cells and their ability t
86                         Our results reveal a synaptogenic function of TRPV1 in a specific interneuron
87 verall, our studies suggest that besides its synaptogenic function that could promote integration of
88 ing, which likely accounts for their reduced synaptogenic function.
89  variants and found that five attenuate this synaptogenic function.
90 t promote gray matter astrocyte identity and synaptogenic function.
91  arrest is independent of its Rac1-dependent synaptogenic function.
92 APP cis-/trans-directed dimerization and APP synaptogenic function.
93 ding is necessary but not sufficient for its synaptogenic function.
94 ng axons of cocultured neurons, suggesting a synaptogenic function.
95                                    Astrocyte synaptogenic functions are dependent on the establishmen
96                                  To test the synaptogenic functions of LAR-RPTPs, we conditionally de
97                         Here, we investigate synaptogenic functions of the secreted extracellular dea
98 hilin, forming a trans-cellular complex with synaptogenic functions.
99 ctivity promotes alternative splicing of the synaptogenic Galpha(s)-coupled variant of LPHN3.
100 nd tumor-cell-state-dependent differences in synaptogenic gene expression associated with neuron-tumo
101  circuit connections and form the basis of a synaptogenic hypothesis of depression and treatment resp
102 s regulated by presynaptic expression of the synaptogenic immediate early gene NPTX2 by pyramidal neu
103 and can block interaction with transmembrane synaptogenic ligands of neurexin.
104 apses are generated by an astrocyte-mediated synaptogenic mechanism in response to cocaine experience
105   Furthermore, this study identifies a novel synaptogenic mechanism in which a single gene product co
106        Here, we show that this developmental synaptogenic mechanism is utilized during cocaine experi
107           These results establish FGF22 as a synaptogenic mediator in the adult nervous system and a
108 ta4, which complexes with CaV1.4 and the rod synaptogenic mediator, ELFN1, for trans-synaptic alignme
109 pecific expression pattern of genes, such as synaptogenic modulator sparc and transcriptional factors
110 ells in the olfactory bulb (OB), express the synaptogenic molecule C1ql3.
111     Although agrin is the best-characterized synaptogenic molecule, its mechanism of action remains u
112 tic process formation and re-expression of a synaptogenic molecule, thrombospondin-1 (TSP-1), apart f
113 s process is controlled by a balance between synaptogenic molecules and proteins that negatively regu
114      The present study aimed to identify the synaptogenic molecules in SC-CM.
115  reactive oxygen species and lower levels of synaptogenic molecules.
116 nal synapse differentiation, consistent with synaptogenic MTG functions.
117 l networks were not those predicted based on synaptogenic outcomes in two-cell networks.
118  factor beta (TGF-beta) signaling is a novel synaptogenic pathway for cortical neurons induced by mur
119  the mammalian target of rapamycin complex 1 synaptogenic pathway; the CRF-induced EPSCs required an
120  diagnosis to the activation of neuronal and synaptogenic pathways at recurrence following therapy.
121 ent by activation of neuronal transition and synaptogenic pathways in recurrent tumors.
122  loss of synapses: pathological reduction of synaptogenic PKC isozymes and their downstream synaptoge
123       Second, the results demonstrate that a synaptogenic process that controls excitatory inputs to
124 neuromuscular junction, steps regulating the synaptogenic program at central cholinergic synapses rem
125 d extrinsic trophic factors in executing the synaptogenic program.
126                        Although they display synaptogenic properties in heterologous systems, the fun
127 e show that dimerization is required for the synaptogenic properties of neuroligin and likely serves
128 ligand thrombospondin-1, responsible for the synaptogenic properties of the alpha2delta-1 receptor, w
129 f postsynaptic neuroligin with regard to its synaptogenic properties: its basal state as a constituti
130 and emphasize the evolutionary aspect of the synaptogenic property of astrocytes, thus shedding light
131 he results exemplify how a structure-encoded synaptogenic protein complex is also used for repulsive
132 identify an interaction between Trio and the synaptogenic protein Neuroligin 1 (NLGN1) in the brain.
133 re AAV-X1-mediated ectopic expression of the synaptogenic protein Sparcl1/Hevin in brain endothelial
134 es, and expression of the astrocyte-secreted synaptogenic protein Sparcl1/Hevin, a key regulator of s
135 neurocan as an astrocyte-secreted inhibitory synaptogenic protein.
136                   Several astrocyte-secreted synaptogenic proteins controlling excitatory synapse dev
137                 First, the data support that synaptogenic proteins guide connectivity and can functio
138 A, have been recently demonstrated to act as synaptogenic proteins that can single-handedly induce th
139           These studies identify TSPs as CNS synaptogenic proteins, provide evidence that astrocytes
140 brain depends on the coordinated activity of synaptogenic proteins, some of which have been implicate
141 exposure level, BPA completely abolishes the synaptogenic response to estradiol.
142 training and lesions resulted in an enhanced synaptogenic response.
143     Together, our findings suggested a novel synaptogenic role of NRG1 in excitatory synapse developm
144 r, alpha2-1 has also been proposed to play a synaptogenic role, independent of calcium channel functi
145   These results suggest the involvement of a synaptogenic signal common to glutamate and GABA synapse
146         Furthermore, we identify BDNF as the synaptogenic signal produced by these nonneuronal cells.
147 restrain synaptic growth by downregulating a synaptogenic signal.
148 d has been found that modulates a retrograde synaptogenic signal.
149 e results uncover a mechanistic link between synaptogenic signaling and axonal transport.
150  a Rac1 activator previously identified as a synaptogenic signaling protein, contributes to establish
151                              Whether and how synaptogenic signals (e.g., adhesion) at axo-dendritic c
152                                    How local synaptogenic signals intercept synaptic cargo in transpo
153 ts show that actin polymerization induced by synaptogenic signals is necessary for the movement and f
154  cell-permeant F-actin-binding toxin, before synaptogenic stimulation, and then probing new actin ass
155 naptogenic PKC isozymes and their downstream synaptogenic substrates, such as brain-derived neurotrop
156 elicits spontaneous somatic Ca2+ transients, synaptogenic thrombospondin 1 (TSP-1) release, and synap
157                 Ultrastructural evidence for synaptogenic triggers during slice preparation was inves
158 ctions, LAR-RPTPs are thought to function as synaptogenic wiring molecules that promote neural circui

 
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