ライフサイエンスコーパス: synergistic effect

1 sponses (that is, additive, antagonistic and synergistic effects).

2 e recognition process, resulting in a strong synergistic effect.

3 cer and pancreatic cancer cell models have a synergistic effect.

4 inhibitory CSPGs did not have a significant synergistic effect.

5 QS-17/18 and QS-21 analogues does not show a synergistic effect.

6 nce longer-term treatment outcomes through a synergistic effect.

7 a-terpinene increased its activity showing a synergistic effect.

8 together with IL-4 failed to demonstrate any synergistic effect.

9 defects, and loss from both cell types has a synergistic effect.

10 , their ecological roles, and their possible synergistic effects.

11 eated with venetoclax and romidepsin showing synergistic effects.

12 general atopic disease loci, which can have synergistic effects.

13 ess, and goblet cell metaplasia, without any synergistic effects.

14 in the MIC of the antibiotic, demonstrating synergistic effects.

15 wise and contends that both pathologies have synergistic effects.

16 mbined inhibition of p300/CBP and BET showed synergistic effects.

17 oups within a framework, leading to emergent synergistic effects.

18 y of combinatorial cell populations exerting synergistic effects.

19 de-to-triazole substitutions for additive or synergistic effects.

20 zole with oral triazoles potentially induces synergistic effects against AF infection.

21 elimination of regulatory T cells had potent synergistic effects against metastatic disease that was

22 ation with chemotherapy, which can achieve a synergistic effect and a decrease in chemoresistance.

23 urements showed that TCNQ and GO triggered a synergistic effect and exhibited an unexpected electroca

24 Notably, the hybrid CPT-Cap prodrug showed a synergistic effect and significantly enhanced potency ag

25 in combination with MEK inhibitors displayed synergistic effects and induced apoptosis in MEKi-resist

26 scavenging capacity of carotenoids, such as synergistic effects and solubility, are sometimes overlo

27 fast computational tools for predicting drug synergistic effects are needed to guide experimental des

28 t in homogeneous conditions showed that this synergistic effect arises from the direct connection bet

29 t lower concentrations was attributed to the synergistic effect at the RGO/SnO(2) interface.

30 Additionally, we observed weaker synergistic effects at a distal GHI-subdomain locus.

31 feeds and eyestalk ablation and reveal their synergistic effects at the transcriptomic level through

32 and temperature tunable strategy wherein the synergistic effect between [hmim]Br-ArSO(2)Cl leads excl

33 We report here, and rationalize, a synergistic effect between a non-noble metal oxide catal

34 m of the present work was to investigate the synergistic effect between antibodies directed toward di

35 cantly enhance by OA treatment, indicating a synergistic effect between BMP2 and OA.

36 cell proliferation of WT MEFs, suggesting a synergistic effect between CARM1 and PRMT6 inhibitions.

37 The synergistic effect between miR122 and PTX was confirmed

38 gin or anti-PD-1 therapy alone, indicating a synergistic effect between PD-1 inhibitors and immunomod

39 on on the molecular mechanism reveals that a synergistic effect between Pt, NbOx species and acidic s

40 The synergistic effect between RB and C(KLAKLAK)(2) has been

41 This work demonstrated a synergistic effect between rGO and PPy for the BESs perf

42 5 as mediated through SETD1, suggestive of a synergistic effect between SETD1 and p65 in the modulati

43 here the growth kinetics are controlled by a synergistic effect between strain and entropy.

44 effects of common variants and demonstrate a synergistic effect between SZ eQTL genes that converges

45 activity of metallic atoms and enhancing the synergistic effect between the inner selenides and surfa

46 ectronic structural features suggests that a synergistic effect between the ligand and cobalt in Co(I

47 This synergistic effect between the two sequential reactions

48 This modification results in a strong synergistic effect between these two constituents leadin

49 igand-functionalized NPs, we showcase here a synergistic effect between these two NP types during the

50 Our study demonstrates that the synergistic effect between TLR4 and TLR3 in macrophages

51 se and benefits and to explore the potential synergistic effects between diarrhea and ARI.

52 Synergistic effects between nsPEF and the moderately ele

53 Synergistic effects between picoloyl and the accompanyin

54 ron mediators and the existence of favorable synergistic effects between Ppy and the AuNPs.

55 moter elements affect burst size and uncover synergistic effects between TATA and initiator elements,

56 The synergistic effects between the hierarchically porous 1D

57 The synergistic effects between the polychaete feeding and t

58 es in different LHCEs indicate the intrinsic synergistic effects between the salt and the solvent whe

59 tro and in vivo Consistent with the in vitro synergistic effects between the SK1-specific inhibitor S

60 The success is attributed to synergistic effects between the two drugs.

61 ite Varroa destructor, no data exist to show synergistic effects between these two stressors.

62 echanisms have the potential for additive or synergistic effects, but experimental design and analyse

63 enhanced conductivities, or even to unclear synergistic effects, but the importance of the defects,

64 3D-hierarchical BRG nanoconstruct exhibited synergistic effect by combining enhanced electrical prop

65 A synergistic effect by methyljasmonate (MeJA) and by comp

66 mation on the silica surface combined with a synergistic effect caused by the silica support itself.

67 on was most likely the result of additive or synergistic effects caused by several compounds.

68 Integration of these two treatments for synergistic effects could eradicate more tumor cells and

69 -paclitaxel therapies and identify potential synergistic effects due to sequencing of the therapies w

70 al molecular stability and also allows for a synergistic effect during collagen folding.

71 The multiple synergistic effects empower the electrocatalyst with exc

72 The synergistic effect enabled by the molecular level integr

73 However, it is unknown whether a synergistic effect exists.

74 that the combination of RSV, PRF, and HA has synergistic effects, explaining their role as a regenera

75 We show that a significant synergistic effect (faster decomposition in mixtures tha

76 )} polyoxometalate (POM) produces a striking synergistic effect featured by high HER performance.

77 A positive interaction and a synergistic effect for the composite endpoint were obser

78 ences compared to the wild-type enzyme, with synergistic effects for combinations of interaction site

79 monstrate the feasibility of utilizing these synergistic effects for controlling the growth rates and

80 hemistry that can be interpreted in terms of synergistic effects, for which the alkali metal is essen

81 Our analyses also suggest a large synergistic effect from river-ocean mixing, global and l

82 Through a synergistic effect from the surface roughness arising fr

83 However, synergistic effects have been so far generally observed

84 e on propranolol's efficacy was opposite the synergistic effect hypothesized a priori.

85 mostly inactive in DTT oxidation, but shows synergistic effect in (*)OH formation in the presence of

86 ticoid treatment in dystrophic muscle have a synergistic effect in alleviating the dystrophic phenoty

87 ATR and Wee1 inhibition had a higher synergistic effect in cancer stem cells than in bulk can

88 The synergistic effect in combination with bortezomib and an

89 versus 0.7+/-0.4%; P=0.001), and there was a synergistic effect in combination with bumetanide (fract

90 ent with IL-17RB-neutralizing antibody has a synergistic effect in combination with gemcitabine for k

91 and citric acid (2.91 mM) showed the higher synergistic effect in DPPH (121.82).

92 neous inhibition of p300/CBP and Notch has a synergistic effect in esophageal adenocarcinoma.

93 lockade of PD-1 and LAG-3 appeared to have a synergistic effect in generating frequent polyfunctional

94 lockade of PD-1 and LAG-3 appeared to have a synergistic effect in generating frequent polyfunctional

95 Indeed, IFN-beta shows a synergistic effect in inducing the IRE1 axis of the UPR.

96 ific Tregs, but not with polyclonal Tregs, a synergistic effect in prolonging skin allograft survival

97 TGF-beta/Fc and nonlytic IL-2/Fc exert a synergistic effect in promotion of alloengraftment and d

98 The complex of Fe-SRFA showed a strong synergistic effect in the generation of .OH in SLF, whil

99 activity is attributed mainly to an unusual synergistic effect in the layered structure, whereby the

100 ((1)Delta(g)) through a physical process and synergistic effect in the presence of commercial antioxi

101 Combining LPS and CX3CL1 displayed a strong synergistic effect in vitro, but HMOX-1 levels were sign

102 ting of ASCL1 and IGF-1R results in markedly synergistic effects in ASCL1(High) SCLC in vitro and in

103 n with zoledronic acid displayed additive or synergistic effects in cell growth assays in 10 of 11 ce

104 Hit 7a and lead 7ii both showed synergistic effects in combination with existing HCV dru

105 and memantine (triple combination) produces synergistic effects in extracellular levels of acetylcho

106 us a platform to unambiguously screen the M synergistic effects in improving the electrocatalytic ac

107 tic-like behaviors in the offspring, and has synergistic effects in inducing neuroinflammation, monoc

108 sitized PC cells to enzalutamide, leading to synergistic effects in inhibiting cell invasion in vitro

109 se 1 and RhoA/Rho kinase (ROCK) leads to the synergistic effects in KRAS-mutant cancers.

110 howed that PTEN loss and activated Kras have synergistic effects in promoting development of IPMN and

111 or VE-822 and oxaliplatin resulted in strong synergistic effects in six different colorectal cancer c

112 -1R, Src and c-Met/ALK, respectively) led to synergistic effects in some of the cell lines examined.

113 Chinese Medicinal (TCM) formulae can achieve synergistic effects in therapeutics and antagonistic eff

114 s to uncover pairs of genes with potentially synergistic effects, including a potential synergy betwe

115 reatments using combinations of drugs with a synergistic effect is attractive but proves to be highly

116 Notably, the synergistic effect is dependent on type I IFN and TNF-al

117 This synergistic effect is likely the result of both passive

118 ures the range of other phenotypes that show synergistic effects is usually unknown.

119 Such synergistic effects lead to superior HER catalytic activ

120 PV-like phenotype, their mixture produced a synergistic effect manifested by a positive Nikolskiy si

121 on cancer cells, suggesting that additive or synergistic effects may be achieved through the positive

122 tivity of cancer cells with a supra-additive synergistic effect of "0 + 1 > 1." Noteworthy is that "D

123 ensitive electrochemical sensor based on the synergistic effect of 7,7,8,8-tetracyanoquinodimethane (

124 The synergistic effect of acidic amino acids with Cip was ob

125 s (mainly (*)OH and CH(3)C(O)OO(*)), and the synergistic effect of all mechanisms involved) to the ov

126 ion hydrogel to maintain ADSC functions, the synergistic effect of AM with ADSC in preventing the cat

127 The results also showed that the synergistic effect of AM-ADSCs was more pronounced in pr

128 INTERPRETATION: Our study identified a synergistic effect of amyloid and tau deposits and demon

129 The synergistic effect of anti-ADAMTS13 IgG antibody in the

130 Our study also shows that the synergistic effect of antibodies is modulated by the nat

131 A similar expression pattern and synergistic effect of Arntl manipulation was observed in

132 her with HsRAD51, potentially explaining the synergistic effect of attenuating the expression of both

133 r performance was mainly originated from the synergistic effect of B and N co-doping, high N content

134 d on the olefinic substrates and reveals the synergistic effect of Bronsted acidic surface sites and

135 s including cirrhosis suggesting a potential synergistic effect of cardiac dysfunction on fibrosis ri

136 tracellular vesicle (EV) transfer blocks the synergistic effect of coculture, identifying EVs as the

137 This is the first study to investigate the synergistic effect of colistin/doripenem combination on

138 Synergistic effect of combining D-amino acids with Cip w

139 Factorial analysis suggested a synergistic effect of combining nutrition education and

140 Factorial analysis suggested a synergistic effect of combining nutritional education an

141 In this study, we investigated the synergistic effect of ethanol and acetaldehyde on the ti

142 We observed a synergistic effect of FASN inhibitors with gemcitabine i

143 ated SUMOylation drives GA by regulating the synergistic effect of GATA2 and NF-kappaB and consequent

144 ivity of this sensor was good as a result of synergistic effect of graphene and AuNPs (2D and 0D nano

145 The synergistic effect of graphene and AuNPs, which facilita

146 ghly positively charged nature, the possible synergistic effect of heterometals in the necklace, and

147 Owing to the synergistic effect of homogenization and normalization o

148 Furthermore, we find that the synergistic effect of inhibiting both mitochondrial tran

149 This synergistic effect of KirBac1.1 in bacteriohopanetetrol-

150 The synergistic effect of LTC4 with IL-33 was completely dep

151 een diabetes mellitus and heart failure, the synergistic effect of managing both conditions, and the

152 activity, and anticancer activity reveals a synergistic effect of MYC inhibition and topoisomerase I

153 Due to the likely synergistic effect of N dopant and V(O) , the V(O) -rich

154 or local and systemic bone regeneration, the synergistic effect of Nell-1 with BMP-2 on osteogenesis,

155 duction of rice has been elucidated, and the synergistic effect of nZVI treatment and rice cultivatio

156 ildren as the reference group, we observed a synergistic effect of overweightness and early pubertal

157 -induced anorexia and necessary for the full synergistic effect of P-NT and liraglutide combination t

158 The synergistic effect of Pt and Pd in alloys containing bot

159 on dystrophic muscle, but also revealed the synergistic effect of RhoA/ROCK inhibition and glucocort

160 The synergistic effect of selective aptamers & high sensitiv

161 Together, our results support a synergistic effect of severe ADAMTS13 deficiency and com

162 es lithium dendrite growth but also brings a synergistic effect of storing lithium via a reversible t

163 We observed a synergistic effect of T and WSD on gene expression, resu

164 we here demonstrate, for the first time, the synergistic effect of the combination of DMAP/HCl/Schrei

165 mpared with ZIF-8 presumably a result of the synergistic effect of the five metal ions as Lewis acid

166 ons we interpret magnetization reversal as a synergistic effect of the metastable ferroelastic switch

167 electrocatalytic activities originate from a synergistic effect of the N, S heteroatom doping and uni

168 The synergistic effect of the nanocomposite components was s

169 The synergistic effect of the steric bulk groups and pai-sta

170 A synergistic effect of the two metals was found.

171 These findings suggest a synergistic effect of the two variants.

172 We further demonstrate a synergistic effect of these HDACi with Vx809, which can

173 vitro studies in porcine skin confirmed the synergistic effect of these strategies in enhancing epid

174 0beta and p110gamma completely prevented the synergistic effect of TPO on ERK1/2 phosphorylation and

175 More importantly, the synergistic effect of TPO on phosphorylation of extracel

176 In conclusion, the synergistic effect of TPO on RAP1 and integrin activatio

177 r structural engineering contributing to the synergistic effects of 2D morphology, amorphous structur

178 Our findings demonstrate the synergistic effects of calcipotriol and 5-FU treatment i

179 ine which species are most vulnerable to the synergistic effects of climate change and habitat loss i

180 Significant alterations to known synergistic effects of co-infection were noted in the al

181 r most likely to respond to PRMT inhibition, synergistic effects of combined PRMT5 and type I PRMT in

182 Synergistic effects of contact-killing and protein-repel

183 Synergistic effects of depressive disorder and NR3C1 hyp

184 0 unique diets; we quantified individual and synergistic effects of dietary macronutrients and the mi

185 e and may promote understanding of potential synergistic effects of disparate stresses in this critic

186 l emphasis on preparative techniques and the synergistic effects of enzymes and MOFs.

187 ect on the alpha-FAPbI(3) phase owing to the synergistic effects of epitaxial stabilization and strai

188 n thoroughly studied in various aspects, the synergistic effects of feeding with live feeds and the a

189 In this study, we have investigated the synergistic effects of Ga doping on the TE performance b

190 ic community-to quantify the independent and synergistic effects of genetic, lifestyle, and other env

191 eping therapy "just right," we show that the synergistic effects of immune activation and chemotherap

192 Synergistic effects of immunotherapy with pembrolizumab

193 Furthermore, we evaluated the synergistic effects of itraconazole and paclitaxel using

194 In particular, we report synergistic effects of mitogen-activated protein kinase

195 In the study, we aimed to explore the synergistic effects of multiple risk factors on birth de

196 reatment for MDR-related tumors based on the synergistic effects of P-gp inhibition, enhanced endocyt

197 tion and phenotypic maintenance, akin to the synergistic effects of potent growth factors such as ins

198 The present study investigates the synergistic effects of predictability and hedonic respon

199 Herein, we report the synergistic effects of reduced nontronite (rNAu-2) and e

200 s to pro-differentiation signals, suggesting synergistic effects of rejuvenation and pro-differentiat

201 These findings highlight the synergistic effects of scavenging and predation risk in

202 Theoretical calculations reveal that the synergistic effects of Se vacancies and subsequent P dis

203 to any individual antibiotic or require the synergistic effects of several antibiotics, we treated m

204 Through the synergistic effects of size exclusion and charge repulsi

205 These synergistic effects of solar-wind protons and micrometeo

206 these observed anomalous growth rates to the synergistic effects of the catalytic properties of Pt an

207 Due to the synergistic effects of the CNT substrate and Mo(2) C cat

208 T calculations, which highlight the powerful synergistic effects of the Si:-->Ni moiety in the breaki

209 roadband photodetection is attributed to the synergistic effects of the spatial nonuniform collective

210 nist mixtures is due to additive rather than synergistic effects of the specific antagonist combinati

211 improves functional outcome in mice with no synergistic effects of the used EphA4 targeted therapy.

212 dditionally, studies have yet to examine the synergistic effects of the various P gene products on pa

213 We achieved synergistic effects of these two hormones and mitigation

214 onmental stressors can strongly increase the synergistic effects of toxicants.

215 elength from 300 to 750 nm demonstrating the synergistic effects of two different polymers.

216 In addition, synergistic effects of US on EC treatments were evaluate

217 Our results highlight the potential for synergistic effects of warming and biodiversity loss on

218 ait locus (QTL) on chromosome 7, which had a synergistic effect on body weight gain and fat deposit w

219 Furthermore, a synergistic effect on breast cancer (MCF-7) and melanoma

220 e mutant, combining both mutations, showed a synergistic effect on CO binding rates.

221 by etoposide in AIRE-expressing cells had a synergistic effect on genes with low expression levels.

222 beneficial treatment because of the positive synergistic effect on growth plate and bone structures.

223 A synergistic effect on hD4R levels is noted when cytoplas

224 However, LDL did not exert a synergistic effect on HDL cholesterol efflux capacity in

225 PI3K and Tiam1 to the apical membrane has a synergistic effect on membrane remodeling.

226 ntially by the same stimulus, which exerts a synergistic effect on PDCD4 expression and thereby helps

227 A synergistic effect on phage restriction was observed whe

228 tylation of highly methylated keratins has a synergistic effect on prolonged stability.

229 heir mixtures were determined to examine the synergistic effect on the antioxidant activity.

230 ion of TET1 and a VP64 transactivator have a synergistic effect on the reactivation of the inactive a

231 s, and end products of lipid oxidation had a synergistic effect on TLR2 activation.

232 sults showed that N and CO(2) enrichment had synergistic effects on alpine grassland communities.

233 egulated Hsf1 transcriptional activity, with synergistic effects on both gene expression and cellular

234 cted to identify which gene combinations had synergistic effects on clinical outcome in lung cancer s

235 n roots, mycorrhizal fungi and PGPR can have synergistic effects on growth and systemic priming of wh

236 orinostat/SAHA, the CARM1 inhibitor achieved synergistic effects on HIV-1 activation.

237 r extinction in rodents and may have similar synergistic effects on human exposure therapy, but the e

238 LR7/8 ligands have been demonstrated to have synergistic effects on innate and adaptive immune respon

239 of targeting RNPs in the same nanoparticle, synergistic effects on lipid metabolism are observed in

240 tion gave higher efficacy of CO(2) indicated synergistic effects on melanosis and TMA inhibition.

241 etween MRTF-A and YAP are suggested by their synergistic effects on SRE.L- and TEAD-luciferase expres

242 sistent with this idea, LEC2 and ABI3 showed synergistic effects on the activation of the OLE1 promot

243 Obesity and air pollution may have synergistic effects on the development of DSPN.

244 dings thus suggest that the RBD and CRD have synergistic effects on their membrane dynamics, with CRD

245 lin receptor attenuated pAkt T308 and showed synergistic effects on viability.

246 First principle simulation reveals this synergistic effect originates from the unique Fe-Cu coor

247 Due to the synergistic effect originating from the conjugated inner

248 h defects, and examine temporal trend of the synergistic effects over time.

249 role in the enhanced disinfection, while the synergistic effect presented a greater contribution, whi

250 The prominent synergistic effects produced by the concomitant inhibiti

251 The addition of food waste caused a synergistic effect, raising methane production from the

252 Their apparent synergistic effect reported in previous observational st

253 in and AaIT (Na(+) channel blocker) produced synergistic effects, requiring 45% fewer spores to kill

254 in a single porphyrin core exhibits a great synergistic effect, resulting in high affinity toward C(

255 on of both pesticides and food stress caused synergistic effects shown by an MDR = 10.9 even at 1 mug

256 tability of the WW domain due to a favorable synergistic effect that depends on the hydrophobicity of

257 ropic and metabotropic 5-HT receptors have a synergistic effect that is critical to both electrophysi

258 proposed that it is the combination of these synergistic effects that leads to OTFTs with a maximum h

259 model further proved tretinoin had a better synergistic effect to increase sunitinib sensitivity to

260 on of nonlytic IL-2/Fc and TGF-beta/Fc had a synergistic effect to promote engraftment and resulted i

261 ACCT demonstrates synergistic effects to enhance cardiac regeneration and

262 Additionally, synergistic effects turn into antagonistic effects when

263 d the enantiopure comonomers, highlighting a synergistic effect upon coassembly of the three monomers

264 and TAG to 3.8% dry weight, demonstrating a synergistic effect upon combining these mutations.

265 The magnitude of the synergistic effect varied between 1.06 and 1.24 dependin

266 omolar concentrations (0.019-1.83 muM) and a synergistic effect was achieved when Methylene Blue was

267 This synergistic effect was enhanced against virus harboring

268 This synergistic effect was evident only when the two vaccine

269 mutants were similarly impaired, a dramatic synergistic effect was found for the double mutant acros

270 A synergistic effect was observed between aminophylline an

271 A synergistic effect was observed following treatment of C

272 ed approach, which showed that the strongest synergistic effects were observed at three of the critic

273 Synergistic effects were observed between (beta-carotene

274 ed the permeability of IEC monolayers, had a synergistic effect when knocked down from both cell type

275 tin were the principal constituents that had synergistic effects when used at the optimal ratio.

276 yloid precursor protein (APP) and mediates a synergistic effect, when combined with a beta-secretase

277 t the remarkable performance originates from synergistic effects where the Mn sites bind O(2) and the

278 Our data revealed complex synergistic effects, whereby tN-Ras binding was higher o

279 ogical drug profiles can produce additive or synergistic effects while reducing side effects and sign

280 inhibitors targeting histone methylation for synergistic effects while still maintaining selectivity.

281 ality litter in mixtures shows a significant synergistic effect, while additive effects are observed

282 absorbed more N) within mixtures, a possible synergistic effect, while Iris ensata 'Rising Sun' perfo

283 rochloraz >=32 mug/L, we observed a marginal synergistic effect with a model deviation ratio (MDR) =

284 low" protein intake or 2) dietary protein's synergistic effect with Ca+/-D intake on bone health out

285 ost importantly, METTL3-m(6)A-CDCP1 axis has synergistic effect with chemical carcinogens in promotin

286 Notably, glutamine starvation has a synergistic effect with cisplatin, a component of the cu

287 e the CyRPA/RIPR combination showed a modest synergistic effect with Hewlett's [Formula: see text] Ad

288 ruses, in vitro drug resistance barrier, and synergistic effect with oseltamivir.

289 g the rainy season and drought period, but a synergistic effect with other flavonoids and isoflavonoi

290 CPPB displays a strong synergistic effect with paclitaxel against growth-inhibi

291 sociated with severe periodontitis and has a synergistic effect with poor oral hygiene, suggesting mo

292 e bacteria is still not clarified, even if a synergistic effect with the bisguanidine chlorhexidine o

293 In particular, MMAR showed a strong synergistic effect with the PR-D212N,F234S double mutant

294 e pleuromutilin derivative 1 displays strong synergistic effects with doxycycline in a wide range of

295 Genetic analyses indicate that eno exhibits synergistic effects with mutations at the LOCULE NUMBER

296 ic effects of specific terpenoids as well as synergistic effects with other active compounds in the p

297 4, IU1, reversed HIV-1 latency and displayed synergistic effects with other latency reversal agents.

298 They also exhibit strong synergistic effects with standard chemotherapy.

299 ios in cb-ApDCs can be tuned for an enhanced synergistic effect without the need for complex chemistr

300 totherms with the potential for detrimental, synergistic effects; yet, effects of these stressors rem