ライフサイエンスコーパス: synergize

1 Dietary caffeine at a human-relevant dose synergizes adverse peripheral and central responses to a

2 A promising fluconazole-synergizing anticholinergic drug, dicyclomine, increases

3 However, critical pathways synergizing antigen-BCR interaction and antigenic peptid

4 anodrugs could offer a promising strategy to synergize both symptom control and disease modification

5 Cyt1Aa is lipophilic and synergizes Bti Cry proteins by increasing midgut binding

6 The cytokines functionally synergize, but their production kinetics widely differ.

7 pre-leukemic NMPs Cebpa and Gata2 mutations synergize by increasing erythroid transcription factor (

8 allowing its nuclear translocation, which is synergized by increased phosphorylation/inactivation of

9 Synergizing compressed sensing and streak imaging with s

10 ing porous materials over SERS hotspots; (5) synergizing conventional metal-based SERS platforms with

11 n the tandem polypeptide, the two WW domains synergized, enhancing the overall binding affinity with

12 e find that strategy and implicit adaptation synergize in driven dimensions, but effectively cancel e

13 e regulated by the RhoA-like GTPase RacE and synergize in the assembly of filaments in the actin cort

14 bind weakly to importin alpha, the two NLSs synergize in the context of the full length NP to confer

15 , demonstrating that adjacent VASP molecules synergize in the elongation of a single filament.

16 combination of blocking and nonblocking Abs synergize in the functional recovery of antigen-specific

17 ABT-263/ABT199 with the CDK7 inhibitor THZ1 synergized in producing growth inhibition and apoptosis

18 tasurface (i.e., meta-transformer), by fully synergizing intrinsic properties of light, e.g., orbital

19 ator-activated receptor alpha (PPARalpha) to synergize its transcriptional activities in hepatic gluc

20 d during evolution provided a mechanism that synergized J recognition and T hydroxylation, ensuring i

21 gly than the isolated RBD or CRD domains and synergizes KRAS partitioning to the membrane.

22 a key component of NADPH synthesis, potently synergizes MB activity.

23 Overall, SUSP4 appears to use two synergizing modules, the p53 rescue motif described here

24 to identify compounds that could potentially synergize or enhance ACT-based immunotherapy of melanoma

25 e demonstrated that small molecular phenamil synergized osteogenesis and bone formation with BMP2 in

26 actly how membrane curvature and composition synergize remains largely unexplored.

27 s of mutations from these different elements synergized, resulting in even greater activity and indic

28 iver combinatorial adjuvants and selectively synergize specific types of immune responses for vaccine

29 0(13) fps and 10(3) frames simultaneously by synergizing spectral encoding, pulse splitting, temporal

30 s, complement therapy with temozolomide, and synergize strongly with everolimus.

31 eactivation of suppressed divergent circuits synergizes strongly with inhibition of the principal onc

32 Moreover, multifunctional NMs synergize surgery with adjuvant therapy (e.g., chemother

33 The prodrugs we describe here synergize the direct killing of bacteria with a simultan

34 site structures that immobilize proteins can synergize the properties of both transducers and molecul

35 , whereas its absence in hematopoietic cells synergized the level of dysbiosis.

36 A key component is the Cyt toxin, which synergizes the activity of the other Cry toxins, thereby

37 biofuel cell structure-based glucose sensor synergizes the advantages of both the glucose biosensor

38 r current studies help to illuminate how Gag synergizes the formation of the virus compartment with R

39 Neuroregeneration is a dynamic process synergizing the functional outcomes of multiple signalin

40 nchronize their pharmacokinetic profiles and synergize their activities in solid tumor treatment, a n

41 in using wet spinning approaches in order to synergize their respective strength and cell interaction

42 ompetition between Fim1 and Adf1 for F-actin synergizes their activities, promoting rapid displacemen

43 of metal-organic frameworks (MOFs) is key to synergizing their attractive synthetic control and poros

44 To test whether diabetes and experimental MI synergize to accelerate atherosclerosis, we performed li

45 tions, mainly G:C-->T:A, and viral processes synergize to accelerate tumorigenesis, perhaps via infla

46 e findings indicate that fat and cholesterol synergize to alter macrophage phenotype, and they also c

47 zed that HIV infection and cigarette smoking synergize to alter the function of alveolar macrophages

48 tion of Treg cells, but how these regulators synergize to control Treg cell homeostasis and function

49 Coordinated glucagon and T3 actions synergize to correct hyperlipidemia, steatohepatitis, at

50 circulating (high-density lipoprotein, HDL) synergize to facilitate Abeta transport across bioengine

51 ventional exploration of point mutations can synergize to generate antibodies with higher affinity.

52 bly cofactor inositol hexakisphosphate (IP6) synergize to generate immature virus particles in vitro

53 armacological inhibitors of the two pathways synergize to impair cancer cell viability in vitro and i

54 gether, our results reveal how Abeta and tau synergize to impair the functional integrity of neural c

55 and Wnt-dependent beta-catenin stabilization synergize to increase beta-catenin-mediated transcriptio

56 urthermore, chemotherapy and PARP inhibitors synergize to inhibit the growth of LMO2-positive tumors.

57 These mechanisms are likely to synergize to maintain diploid cell populations.

58 the risk of older age and prior nkSOT might synergize to make KT too risky, but this has never been

59 nism dictating how curvature and composition synergize to modulate recruitment of lipidated proteins.

60 Cyclase-associated protein (CAP) and Cofilin synergize to processively depolymerize actin filament po

61 A, and a Toll-like receptor 4 agonist, which synergize to produce high levels of type I IFNbeta.

62 The actin nucleators Spire and Cappuccino synergize to promote actin assembly, but the mechanism o

63 eptor (IFN-gammaR) as essential signals that synergize to promote the development and appearance of t

64 ate that fiber hydrogel and serum-free media synergize to provide an optimal environment for the main

65 al chaperone and Bcl-2 family inhibitors can synergize to safely degrade the growth of tumors recalci

66 strate how 2 distinct tolerance pathways can synergize to unleash autoimmunity and have implications

67 and uncovered combinations of mutations that synergized to promote clonal expansion and dominance.

68 tide 1 mimetic liraglutide, the two peptides synergized to reduce food intake and body weight relativ

69 These two tracks have increasingly synergized to underscore the importance of cis-regulator

70 , self-powered glucose indicator system that synergizes two flexible electronic technologies: a flexi

71 ut little is known about how these mutations synergize upon cooccurrence.

72 culate that vascular and myeloid cell ageing synergize, via IL-6 signalling, to accelerate atheroscle

73 omplementary strengths and weaknesses, which synergize when combined to sharpen gene expression bound

74 aeruginosa isolates the activity that can be synergized when used in combination with other classes o

75 selectivity in the presence of hormone, most synergize with 17beta-oestradiol and dafachronic acid re

76 tanding selectivity over related enzymes and synergize with a cytidine analogue against leukemic cell

77 MCDs can synergize with a speckle-associated RNA recognition moti

78 cell lines for kinase inhibitors that could synergize with activation of protein phosphatase 2A (PP2

79 ration is harnessed for immune activation to synergize with an anti-PD-L1 antibody for the treatment

80 We explored the possibility that CoRBS Abs synergize with anti-cluster A Abs to engage Fc-gamma rec

81 ors exert significant antitumor activity and synergize with anti-PD-L1 antibody in lung cancer mouse

82 cally approved PCSK9-neutralizing antibodies synergize with anti-PD1 therapy in suppressing tumour gr

83 bility of polymyxin B nonapeptide (PMBN), to synergize with antibiotics in the presence of EPIs.

84 ve vaccines and host-directed therapies that synergize with antibiotics to prevent pathogen persisten

85 effective maternal HIV-1 vaccine that could synergize with antiretroviral therapy (ART) to eliminate

86 f maternal vaccination strategies that could synergize with ART during pregnancy to achieve the elimi

87 ltiple stages of the parasite life cycle and synergize with artemisinins, suggesting that Pf20S inhib

88 loss of D2-family dopamine receptors did not synergize with bas-1 suppression of tauopathy phenotypes

89 dence that inhibitors of NF-kappaB signaling synergize with BET inhibition in in vitro and in vivo mo

90 rapeutic treatment may have the potential to synergize with beta-lapachone treatment, creating unique

91 HDAC inhibitors synergize with BPTF knockdown against HGG growth.

92 toxic T cell activation and recruitment, and synergize with checkpoint inhibitors, chemotherapy and/o

93 We show that pausing signals synergize with chromatin to control piRNA transcription.

94 henotype, cytolytic function, and ability to synergize with conventional DCs (cDCs) in generating pot

95 ested whether inflammatory tissue conditions synergize with dicarbonyls to induce iCGRP release from

96 The selective WEE1 inhibitor MK-1775 synergize with DNA-damaging agent to inhibit cancer cell

97 dependent effects on dynein motility and can synergize with dynactin to enhance processive dynein mov

98 We proved that AMPs can synergize with EPIs and that this phenomenon can be expl

99 Moreover, LIF-neutralizing antibodies synergize with gemcitabine to eradicate established panc

100 ts voltage-gated l-type Ca(2+) channels that synergize with GluN2A-containing NMDA receptors to drive

101 H3 tail had little effect, but were able to synergize with H4 tail acetylation mimics to further inc

102 itor Nexturastat A with CRBN ligand that can synergize with HDAC6 degradation for the antiproliferati

103 fects downstream from Myo5b loss of function synergize with higher levels of glucocorticoids to activ

104 Antibodies to 4/18 non-HLA antigens synergize with HLA donor-specific antibodies and signifi

105 nostimulation via alphaCD40 is sufficient to synergize with ICB for priming.

106 vivo, low doses of TNF prolong survival and synergize with immune checkpoint inhibitors to promote t

107 e cancer, and show that a PRC1 inhibitor can synergize with immune checkpoint inhibitors to suppress

108 rug delivery particles have the potential to synergize with immunotherapeutics to accomplish these go

109 eutic reactivation of tumor-specific TEs may synergize with immunotherapy by inducing inflammation an

110 the current small molecular drugs that could synergize with immunotherapy, especially anti-PD therapy

111 In this context, insulin can synergize with inflammation to promote proliferation, su

112 er a CB1 positive allosteric modulator would synergize with inhibitors of endocannabinoid deactivatio

113 We report that SMCs synergize with innate immune stimulants and immune check

114 y those of Kdm6a mutations, and both defects synergize with Kras(G12D) to cause PDAC with sarcomatoid

115 1 secreted protein HIV Tat has been found to synergize with KSHV lytic proteins to induce angiogenesi

116 AF chromatin remodeling complex, which could synergize with LIM proteins in tethering ChiLS to enhanc

117 Previous studies have shown that PKA can synergize with low levels of androgen to enhance androge

118 and found that high levels of thrombopoietin synergize with low levels of stem-cell factor and fibron

119 pplied in combination, both KA and anthralin synergize with LRAs representing multiple functional cla

120 more, we show that MAIT cell-derived signals synergize with microbial stimuli to induce secretion of

121 ction with IFN-inducing viruses, are able to synergize with New World Leishmania parasites in both pr

122 entify highly active antileukemic drugs that synergize with NOTCH1 inhibition in T-ALL.

123 resistance in target microbes, and AMPs may synergize with one another and with conventional antibio

124 concerns, since two single-target drugs may synergize with one another through interconnected biolog

125 sed by melanoma cells to identify those that synergize with or cause resistance to checkpoint blockad

126 ts a promising therapeutic strategy that may synergize with other immuno-oncology mechanisms and chem

127 ependent loss-of-function mechanism that may synergize with other neurotoxic effects caused by LRRK2

128 phozoite-infected erythrocytes, PfGARP could synergize with other vaccines that target parasite invas

129 in PDAC and establish current therapies that synergize with PARGi.

130 Nanomedicines synergize with pharmacological and physical co-treatment

131 Here, to identify targets that synergize with PI, we carried out a functional screening

132 ecule inhibitors of the PIM2 and ZAK kinases synergize with PI3K inhibition.

133 ntly, these isoform-targeted HDAC inhibitors synergize with PKC modulators, namely bryostatin-1 analo

134 ow a single sequence-specific pioneer TF can synergize with remodelers to activate sets of genes.

135 regulating motif is not required for PAR2 to synergize with TGF-beta1 to promote cell motility.

136 ene duplicates in specialized cell types can synergize with the acquisition of functional differences

137 mily may induce responses that antagonize or synergize with the activities of another family, cell fa

138 small molecules and identified several that synergize with the antibiotic trimethoprim and/or sulfam

139 or, and paclitaxel, a microtubule inhibitor, synergize with the BET inhibitor JQ1 in TNBC lines.

140 also mediate transcriptional changes and can synergize with the ER to regulate cell function.

141 n long-term engraftment and can specifically synergize with the oncogenic homeobox transcription fact

142 es identified the BCL-2 inhibitor ABT-199 to synergize with tivantinib while cytarabine combination w

143 that gene-targeting ASOs can be selected to synergize with TLR8 agonists currently under investigati

144 est that higher concentrations of BMP9/BMP10 synergize with TNFalpha to induce the up-regulation of e

145 therapy with TDP1 inhibitors is proposed to synergize with topoisomerase targeting drugs to enhance

146 screens to identify bioactive compounds that synergize with TTM in BRAF(V600E)-driven melanoma cells.

147 ing dose of the 5-HT(2C)R agonist WAY163909, synergized with a low dose of WAY163909 to substitute fu

148 nd CDK9 inhibitors including dinaciclib that synergized with ABT-263 through downregulation of MCL-1.

149 -bactericidal concentrations, it effectively synergized with ampicillin to reverse drug resistance in

150 munity to orchestrate adaptive immunity when synergized with an anti-PD-L1 immune checkpoint inhibito

151 However, further inhibition of Mtb's GS synergized with and accelerated the onset of BDQ-mediate

152 TK antibody stimulated T cell activation and synergized with anti-PD-1 or anti-PD-L1 therapy.

153 ression with durable antitumor immunity, and synergized with anti-PD-1 therapy.

154 High-dose AA treatment synergized with anti-PD1 therapy in a syngeneic lymphoma

155 patient-derived TNBC xenografts in mice and synergized with anti-VEGFA treatment to cause tumor stas

156 Blockade of C5a receptor 1 synergized with antiangiogenic Listeria monocytogenes-ba

157 Induction of HLA-I APM by RIG-I synergized with antibodies blocking PD-1 and TIGIT inhib

158 ased viral RNA levels only in dAP7 cells and synergized with antibody for RNA clearance and improved

159 4 as a factor that inhibited cell growth and synergized with approved anti-estrogens and cyclin-depen

160 Gemcitabine activated caspase-3 and synergized with AZD1775 through caspase-mediated cleavag

161 Consistent with the in vivo data, AngII synergized with BAFF to induce IL-10 production by B cel

162 Furthermore, calcineurin blockade synergized with BCL-2 and MCL-1 inhibitors in killing AB

163 The pan-ErbB inhibitor sapitinib synergized with BRAF inhibition in BRAF mutant Bliley TC

164 However, the SAA fragments potently synergized with CCL3 to induce monocyte migration and wi

165 bination lacks activity against MRSA, yet it synergized with compound 73 to kill MRSA in a bactericid

166 Furthermore, GMF synergized with Coronin in inhibiting actin nucleation b

167 Furthermore, CBD-IL-12 potently synergized with CPI to eradicate large established melan

168 Here, we demonstrate that CXCL14 synergized with CXCL12 in the induction of chemokine res

169 Treatment with 17beta-estradiol (E2) synergized with DAC to reduce proliferation.

170 KDM5i synergized with DAC to reduce the viability of luminal b

171 PI3K suppression by mTORC2 inhibition synergized with dasatinib and abolished resistance in vi

172 o induce accumulation of phosphorylated p53, synergized with DFO and MLN-4924 in inducing EBV reactiv

173 MyrAkt2 synergized with Dlx5 to greatly accelerate and enhance t

174 PARGi synergized with DNA-damaging agents (i.e., oxaliplatin a

175 hibited translation in vitro and in vivo and synergized with doxorubicin, ABT-199 (a Bcl-2 antagonist

176 Pharmacological inhibition of Mcl-1 synergized with EGFR inhibition in a panel of geneticall

177 e demonstrated that SOS1 inhibition strongly synergized with EGFR-TKI treatment only in 3D spheroid c

178 and a small-molecule AMPK inhibitor strongly synergized with glucocorticoids, identifying TXNIP, CNR2

179 Checkpoint blockade strongly synergized with heterologous vaccination to enhance over

180 Notably, checkpoint blockade therapy synergized with IL12 to fully enable tumor control by NK

181 ck loop of macrophage-derived IL-10 and this synergized with inhibition of the JNK pathway for limiti

182 Moreover, IRAK1 inhibitors synergized with inhibitors of PIN1, a prolyl isomerase e

183 Further, ABA synergized with insulin to dramatically increase the rat

184 ically release interleukin-33 (IL-33), which synergized with intestinal tuft-cell-derived IL-25 to dr

185 hibition in BRAF mutant Bliley TCC cells and synergized with MEK1/2 inhibition in Bliley and BRAF wil

186 nown to induce expression of these cytokines synergized with MEKi in eradicating tumors.

187 ABZ had negligible effects on Wolbachia but synergized with minocycline or rifampicin (RIF) to deple

188 mic, but not normal, hematopoietic cells and synergized with other antileukemic agents in this regard

189 Moreover, the combination of sAXL synergized with pazopanib and axitinib to reduce ccRCC p

190 The compound synergized with piperacillin-tazobactam (TZP) both in vi

191 printhead consisting of bundled capillaries synergized with programmed movement of the motorized sta

192 ancer cells with a miR-139-5p mimic strongly synergized with radiation both in vitro and in vivo, res

193 However, in both B-ALL and AML, TRC105 synergized with reduced intensity myeloablation to inhib

194 downstream effector for BET degraders, which synergized with small-molecule inhibitors of BCL-xL in t

195 of CRP to PC moieties), but not soluble CRP, synergized with specific TLRs to posttranscriptionally a

196 In both lines of mice, adjunct 5-HTP SR synergized with SSRI to elevate 5-HTExt beyond the SSRI

197 ndent human cohorts (total n > 3,000), aging synergized with stress-related phenotypes, measured with

198 Treatment with the BET inhibitor JQ1 synergized with sulforaphane in colon cancer cells and s

199 Accordingly, 5-NIdR synergized with temozolomide to increase apoptosis of tu

200 le (FX1) BCL6 inhibitors derepressed BIM and synergized with the BH3-mimetic ABT-199 in eradicating M

201 ibitor PET-16 reduced levels of mutant BRAF, synergized with the BRAF inhibitor PLX4032 in vitro, and

202 Notably, both miRNAs synergized with the frontline colorectal cancer chemothe

203 At physiological concentrations, PLA2G1B synergized with the HIV gp41 envelope protein, which app

204 ent, at higher concentrations both cytokines synergized with tumor necrosis factor-alpha (TNFalpha) t

205 n domain in the middle of the proteins (TAM) synergizes with a C-terminal one (TAC).

206 bset of glucose-deprived melanoma cells, but synergizes with acetate to support cell survival.

207 ssion and stabilize beta-catenin, which then synergizes with Activin-induced SMADs to activate a subs

208 ntributes to synaptic dysfunction and how it synergizes with amyloid pathology to cause neuroinflamma

209 R-DOTAP also synergizes with an anti-PD1 checkpoint inhibitor, result

210 pic expression shows antitumor activity, and synergizes with anti-PD-1, notably, with chemotherapy fo

211 Here, we show that inhibition of HDAC6 synergizes with anti-PD-L1 immune checkpoint blockade in

212 A4 synergizes with anti-PD-L1, but not anti-CTLA4, therapy

213 idly bacteriolytic, eradicates biofilms, and synergizes with antibiotics.METHODSIn this superiority-d

214 ice models show that loss-of-function of ZAP synergizes with APC-deficiency to drive malignant colore

215 pharmacological activation of AMPK strongly synergizes with BCL-2/BCL-X(L) inhibitors to activate ap

216 ect spliceosome inhibition in myeloma, which synergizes with carfilzomib and shows potent anti-tumor

217 The enhanced antigen presentation synergizes with CBI to expand and reinvigorate cytotoxic

218 Antigenic reeducation of tolerant T cells synergizes with checkpoint blockade to generate function

219 dampens AML blast regeneration, and strongly synergizes with chemotherapy, doubling the duration of m

220 y destabilizes the p53-MDM2-MDM4 complex and synergizes with cisplatin to intensify p53 function, whi

221 skin transplant model, the addition of IL-2 synergizes with CNIs treatment, promoting intragraft acc

222 of the post-transcriptional suppressor DND1 synergizes with concurrent transcriptional changes to en

223 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR

224 on fluorescence microscopy we show that Wsp1 synergizes with Dip1 to co-activate Arp2/3 complex.

225 escence-associated heterochromatic foci that synergizes with DNA methylation to silence tumor-suppres

226 cally or pharmacologically with chloroquine, synergizes with dual ICB therapy (anti-PD1 and anti-CTLA

227 to gliotoxin, indicating that this compound synergizes with endogenous serotonin to elicit behavior.

228 Our results demonstrate that p53(-/-) synergizes with enhanced oncogenic Nras signaling to tra

229 pression and that chemical PFKFB3 inhibition synergizes with erlotinib in increasing erlotinib's anti

230 Notably, inhibiting cPLA2 synergizes with fatty acid-free diet to restore immunoge

231 In mice, Cdon mutation synergizes with fetal alcohol exposure, producing HPE ph

232 is-benzodioxolylindolinone (azoffluxin) that synergizes with fluconazole against C. auris.

233 ociated with reduced beta-catenin signaling, synergizes with genetically-directed reductions in beta-

234 ribose) polymerase (PARP) inhibitor olaparib synergizes with GLS1 inhibitors to suppress the growth o

235 ssing CeD risk genes, P. aeruginosa elastase synergizes with gluten to induce more severe inflammatio

236 Pharmacological targeting of FSP1 strongly synergizes with GPX4 inhibitors to trigger ferroptosis i

237 ranscription through either of these methods synergizes with HDAC inhibition, and DIPG cells resistan

238 ctopic expression in prostate adenocarcinoma synergizes with hypoxia to suppress androgen signaling a

239 LOX in colorectal cancer synergizes with hypoxia-inducible factor-1 (HIF-1) to pr

240 -suppressive barrier and that its inhibition synergizes with ICIs.

241 es T cell-dependent anti-tumor immunity, and synergizes with immune checkpoint blockade.

242 ntly triggers innate sensing within TME that synergizes with immunotherapy to overcome adaptive resis

243 eclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induc

244 adiation delivered to one tumor-bearing lung synergizes with inhaled NP-cGAMP, eliciting systemic ant

245 on of the MAPK branch but not the FAK branch synergizes with inhibition of the proximal cascade, prov

246 We show that MYC overexpression (MYC(Tg)) synergizes with KRAS(G12D) to induce an aggressive liver

247 UNC-3 synergizes with LIN-39 (Scr/Dfd/Hox4-5) to directly co-a

248 duces the expression of its own receptor and synergizes with local glutamatergic neurons.

249 ion, we demonstrate that PSGR overexpression synergizes with loss of PTEN to accelerate prostate canc

250 ytated FetA bind to LPS, but only the former synergizes with LPS and grass pollen or mite allergens t

251 It synergizes with metabolic reprogramming of T cells to ac

252 recognition motif (RRM) domains of hnRNP L, synergizes with miR-297, reduces VEGFA mRNA translation,

253 otinamide phosphoribosyltransferase (NAMPT), synergizes with MMS to induce cytotoxicity and Aag(-/-)

254 d synergizes with sgs1Delta, whereas sae2-5A synergizes with mre11-nd and exhibits epistasis with sgs

255 Chronic activation of Notch1 synergizes with multiple oncogenic pathways altered in e

256 Our genetic data establish that MNT synergizes with MYC by suppressing MYC-driven apoptosis,

257 ter-mediated expression of LMO1 in zebrafish synergizes with MYCN to increase the proliferation of hy

258 trates how IL-22-induced activation of STAT3 synergizes with NF-kappaB-activating cytokines to enhanc

259 RF as previously proposed; however, GAF also synergizes with NURF downstream from this process to ens

260 In addition, it synergizes with olaparib (a PARPi) to trigger synthetic

261 Finally, we show that G4 stabilization synergizes with other DNA-damaging therapies, including

262 signaling in a shallow PDGF gradient, but it synergizes with other feedback mechanisms to enhance amp

263 diated demethylation of H3K36me3, and JIB-04 synergizes with other latency-reversing agents (LRAs) to

264 Here we show that RSPO3 antagonism synergizes with paclitaxel based chemotherapies in patie

265 ion of the cell to viral infection, but also synergizes with pattern recognition sensing to mount a p

266 servations identify targets whose inhibition synergizes with PI3K inhibitors and nominate potential c

267 Therefore, canonical NF-kappaB activation synergizes with PKR to promote SINV replication in diffe

268 This result suggests GQ folding synergizes with POT1-TPP1 to support telomerase function

269 , we show that phosphatidylethanolamine (PE) synergizes with PS to enhance PS receptor-mediated effer

270 y of these processes is enhanced, namely, PE synergizes with PS to promote PS receptor-mediated virus

271 Interestingly, FDPS overexpression synergizes with PTEN deficiency in PTEN conditionally kn

272 Furthermore, nanovaccine synergizes with radiotherapy to achieve a better therape

273 hat Emei is a novel ER Ca(2+) regulator that synergizes with Ras(V12) to induce tumor growth via JNK-

274 rk homeostasis by blocking fission or fusion synergizes with reduced mitochondrial translation to pro

275 Here the rigidity of cross-linked collagen synergizes with retinoids in the osteogenesis of human m

276 Dual antibody of both receptors synergizes with RT in control of syngeneic mouse breast

277 11-nd for camptothecin (CPT) sensitivity and synergizes with sgs1Delta, whereas sae2-5A synergizes wi

278 is stimulated by high membrane curvature and synergizes with SNX9 BAR domain binding in a process we

279 We also find that the acetyltransferase Gcn5 synergizes with Spt3 to promote global transcription and

280 eatment, and targeting one of these pathways synergizes with statins to produce a robust antitumor re

281 ed macrophages in blocking NK activation and synergizes with T cell-directed immunotherapy, such as a

282 These findings demonstrate that NKTR-214 synergizes with T cell-mediated anti-cancer therapies.

283 t inhibition of pantothenic acid utilization synergizes with the activity of the ergosterol molecule-

284 Nortriptyline further synergizes with the antineoplastic drug gemcitabine to e

285 In human cells, LA supplementation synergizes with the COVID-19 drug remdesivir, suppressin

286 Further, CsA synergizes with the DDA tcyDTDO to kill HER2/EGFR overex

287 GF-beta) expression, whose signaling pathway synergizes with the EGFR cascade, but its role in infect

288 Additionally, complement synergizes with the Fc receptor TRIM21 to block transduc

289 Here, we show that DNMT3A loss synergizes with the FLT3 internal tandem duplication in

290 The consequent receptor clustering synergizes with the Ub-dependent mechanism to amplify RI

291 vealed that the antimalarial activity of B02 synergizes with those of two first-line malaria drugs, a

292 We then found that 3D niche stiffness synergizes with WNT7a, a biomolecule shown to control SC

293 all neutralizing PfRH5 antibodies as well as synergizing with antibodies targeting other malaria inva

294 Screening for activators capable of synergizing with HMGN1 in activating DC identified R848.

295 IFNgamma promotes ASC development by synergizing with IL-2 and TLR7/8 ligands to induce genom

296 erred PARPi sensitivity, with ATR inhibitors synergizing with PARPis or sensitizing GSCs.

297 Thus, AKT methylation is an important step, synergizing with PI3K signalling to control AKT activati

298 ORF72, which can lead to autophagy deficits, synergizing with repeat-dependent gain of toxicity.

299 that anti-TAA mAbs are capable of profoundly synergizing with T cell-directed immunotherapies such as

300 ne region and its potential for functionally synergizing with the beta3 extracellular domain (ECD).