ライフサイエンスコーパス: synovial tissue

1 mononuclear cells that are embedded into the synovial tissue.

2 nd they promote leukocyte migration into the synovial tissue.

3 ontrols (P = 0.018) and were demonstrated in synovial tissue.

4 e assay and immunostaining were performed on synovial tissue.

5 uced serum amyloid A expression in ileum and synovial tissue.

6 they promote leukocyte trafficking into the synovial tissue.

7 ravasation through vascular endothelium into synovial tissue.

8 cyte behavior and function in organizing the synovial tissue.

9 be involved in leukocyte trafficking into RA synovial tissue.

10 s of patients with RA, compared with control synovial tissue.

11 essels (angiogenesis), when compared with DA synovial tissue.

12 on from RA compared with osteoarthritis (OA) synovial tissue.

13 n vitro marker of T cell accumulation within synovial tissue.

14 in the synovial fluid and macrophages in the synovial tissue.

15 was performed on RA and osteoarthritis (OA) synovial tissue.

16 topic germinal centres compared with diffuse synovial tissue.

17 lular DNA was detectable in various areas of synovial tissue.

18 he cells synthesizing MASP-1/3 and pro-FD in synovial tissue.

19 erosion, as well as less myeloperoxidase in synovial tissue.

20 mpare the expression of CCR7 and CCL21 in RA synovial tissue.

21 downstream mediator of TNFalpha signaling in synovial tissue.

22 via NF-kappaB or at the genomic level in the synovial tissue.

23 th osteoarthritis and arthritis-free control synovial tissues.

24 by collagenase digestion of two of the five synovial tissues.

25 d in RA, were all abundantly expressed in RA synovial tissues.

26 of mouse and human synovial fibroblasts and synovial tissues.

27 s been observed in rheumatoid arthritis (RA) synovial tissues.

28 nonuclear and endothelial cells in RA and OA synovial tissues.

29 n of PDGFR-alphabeta was also elevated in RA synovial tissues.

30 These findings also extended to synovial tissues.

31 sues from patients with RA but not in normal synovial tissues.

32 roblasts isolated from RA and osteoarthritis synovial tissues.

33 and three fz (fz2, 5, and 7) isoforms in RA synovial tissues.

34 se to MAC and is detected in human renal and synovial tissues.

35 is in whom the synovial fluid (1 patient) or synovial tissue (1 patient) was positive for Tropheryma

36 RT-PCR) was used to identify mRNA for ODF in synovial tissues, adherent synovial fibroblasts, and act

37 the medial femoral condyle cartilage and the synovial tissue adjacent to the central portion of the m

38 nical trials, may lead to the development of synovial tissue analysis as a potential clinical tool fo

39 Synovial tissue analysis confirmed mononuclear leukocyte

40 Synovial tissue analysis has been instrumental in enhanc

41 to investigate the distribution of MTG in RA synovial tissue and also non-RA arthritis and healthy co

42 the activation of infiltrating leukocytes in synovial tissue and are a potential therapeutic target.

43 uman retrovirus-5 proviral DNA is present in synovial tissue and blood specimens from patients with r

44 en are produced by rheumatoid arthritis (RA) synovial tissue and can potentially induce mutations in

45 Pathways Analysis and compared to published synovial tissue and cartilage messenger RNA profiles.

46 sociated with induction of senescence in the synovial tissue and cartilage protection.

47 d CCR5-immunoreactive cells were found in RA synovial tissue and colocalized with CD68+ macrophages.

48 a, is elevated in human rheumatoid arthritis synovial tissue and correlates with inflammatory cell in

49 Synovial tissue and fibroblast-like synoviocytes from RA

50 By forming a complex with p38 in synovial tissue and FLS, these kinases can potentially b

51 in whose expression is increased in inflamed synovial tissue and fluid in human rheumatoid arthritis

52 in inflammation by recruiting leukocytes to synovial tissue and fluid-and subsequently contributing

53 TSG-6 binds to hyaluronan in inflamed synovial tissue and forms a complex with a serine protea

54 We have now extended these findings to synovial tissue and further explored the mechanism under

55 sed at elevated levels in normal, OA, and RA synovial tissue and in primary RA synoviocytes.

56 cyclooxygenase (COX-2) are found both in the synovial tissue and in the cartilage.

57 Freshly isolated rheumatoid synovial tissue and isolated RA synovial fibroblasts inv

58 ther, these studies implicate cadherin-11 in synovial tissue and lining layer formation and provide a

59 or necrosis factor alpha and IL-1beta in the synovial tissue and lower protein levels of IL-1alpha an

60 e induction of apoptosis of cells within the synovial tissue and lymph nodes of lpr-APC-AdFasL-treate

61 was examined by PCR on genomic DNA of paired synovial tissue and peripheral blood cells of RA patient

62 d in vitro functional assays with rheumatoid synovial tissue and primary cells.

63 NR4A messenger RNA levels in synovial tissue and primary synoviocytes were measured b

64 so analyzed the expression of neuropilins in synovial tissue and SF, as they may interact with vascul

65 RA synovial tissue and synovial fluid macrophages expressed

66 T cell cytokine IL-17 is expressed in the RA synovial tissue and synovial fluid.

67 en demonstrated in rheumatoid arthritis (RA) synovial tissue and synoviocytes, no information is avai

68 tory leukocytes in rheumatoid arthritis (RA) synovial tissue and to the growth and proliferation of R

69 Synovial tissue and whole blood from 75 patients with rh

70 hemokines, and catabolic factors that damage synovial tissues and can activate free nerve endings in

71 t-like synoviocytes (FLS) were isolated from synovial tissues and incubated with the NO donor S-nitro

72 d severity, enhanced osteoclast abundance in synovial tissues and osteoclastogenic propensities of bo

73 A synovial fibroblasts were isolated from RA synovial tissues and used between passages 3 and 9.

74 macrophage-derived chemokine (CCL22) in the synovial tissue, and also had reduced acute and late-sta

75 ed fibrinogen (CF) is abundant in rheumatoid synovial tissue, and anti-citrullinated protein Ab-posit

76 Vascularization was determined in the synovial tissue, and correlations with inflammation were

77 Apo A-I product was generated by RT-PCR from synovial tissue, and further, by the demonstration that

78 th inflammation in rheumatoid arthritis (RA) synovial tissue, and PAD2 and citrullinated proteins are

79 ynovium of RA patients compared with control synovial tissue, and that it is predominately expressed

80 th a stromal cell line (SCL) derived from RA synovial tissue, and the effects on apoptosis and expres

81 ions identified in rheumatoid arthritis (RA) synovial tissue are dominant negative.

82 Specific pathways within synovial tissues are emerging as associated with diverse

83 cell-membrane factors produced by rheumatoid synovial tissues are likely to play a role in the initia

84 The expression of Bim was reduced in RA synovial tissue as compared with controls, particularly

85 nic inflammatory synovial lesions and normal synovial tissue as well as from fetal lung and adult ski

86 was significantly low in RA serum, SFs, and synovial tissues, as well as in the serum and joints of

87 ontrast enhancement was measured in inflamed synovial tissue at half dose (0.05 mmol per kilogram of

88 In a series of 64 synovial tissue biopsies, lymphoid follicles with germin

89 ere found in a high proportion of RA patient synovial tissues but also in non-RA arthritis control ti

90 receptor expression were investigated in RA synovial tissue by immunohistochemistry and 2-color immu

91 and NOD2 expressions were determined in mice synovial tissue by RT-PCR.

92 suggest that p53 mutations are induced in RA synovial tissues by inflammatory oxidative stress.

93 of CXC chemokine receptor (CXCR)4 expressing synovial tissue CD4(+) memory T cells was significantly

94 levels of CD130 messenger RNA and protein in synovial tissue CD4+ T cells suggested that CD130 is up-

95 In the synovial tissue, CD8+ T cells were the major source of I

96 Synovial tissue cells participate in lymphocyte recruitm

97 duction of neutrophil-active chemokines from synovial tissue cells.

98 t of arthritis, and their migration into the synovial tissue coincides with the onset of clinical dis

99 fe and well tolerated procedure that enables synovial tissue collection from most joints/patients wil

100 Analysis of human RA synovial tissue confirmed that PBEF immunolocalized in a

101 ory sites, such as rheumatoid arthritis (RA) synovial tissue, contain large numbers of activated B ce

102 y expressed in RA B cells from patients with synovial tissue containing ectopic germinal centres comp

103 P3K gene expression in RA and osteoarthritis synovial tissue demonstrated mitogen-activated protein k

104 y analysis and real-time RT-PCR of the ankle synovial tissue demonstrated that hTNF/SphK1(-/-) mice h

105 This was due to lytic viral infection of synovial tissues demonstrated by PCR, immunohistochemist

106 y shown that revascularization of minced JRA synovial tissues engrafted into SCID mice correlated wit

107 ated CD8(+)CD28(-)CD56(+) T cell clones from synovial tissues, expanded them in vitro, and adoptively

108 Synovial tissue explants were stimulated with VEGF, and

109 Giant cells that form within OA synovial tissue express high levels of cathepsin K mRNA.

110 indings in RA PB, CD4+ T cells in the SF and synovial tissue expressed low levels of CD126.

111 Osteoarthritis synovial tissues expressed much less wnt5a and fz5.

112 Synovial tissue expression of alphav integrins was deter

113 Synovial tissue expression of the chemokines interleukin

114 lood in vitro-differentiated macrophages, RA synovial tissue fibroblasts, and human microvascular end

115 tissue, including rheumatoid arthritis (RA) synovial tissue fibroblasts.

116 In the context of inflamed synovial tissues, FLS may be an important and hitherto o

117 isfatin/PBEF in the molecular patterns of RA synovial tissue, focusing on RA synovial fibroblasts (RA

118 DNA damage in inflamed synovium, we analyzed synovial tissues for microsatellite instability (MSI).

119 correlated with numbers of free microscopic synovial tissue fragments (r = 0.826, P < 0.0001).

120 nic factors in fresh JRA synovium and in JRA synovial tissue fragments that had been minced and then

121 derived from CD19(+) B cells within RA human synovial tissues frequently react against NETs.

122 Synovial tissue from 12 patients with active systemic JI

123 63 patients with Lyme arthritis (LA) and in synovial tissue from 9 patients.

124 epsin B, and interleukin-1beta (IL-1beta) in synovial tissue from control and affected joints were de

125 gulated in RA synovium compared with control synovial tissue from patients with osteoarthritis or ser

126 TNFalpha production in synovial tissue from patients with RA but not osteoarthr

127 the expression of selected gene products in synovial tissue from patients with RA compared with pati

128 onocytes, and fibroblasts from 51 samples of synovial tissue from patients with RA or osteoarthritis

129 icrovascular endothelium and is expressed in synovial tissue from patients with rheumatoid arthritis

130 Immunohistochemical analysis of synovial tissue from RA and OA patients revealed increas

131 dependent kinase inhibitor p21 is reduced in synovial tissue from RA patients compared to osteoarthri

132 but not SPHK-2) mRNA levels were observed in synovial tissue from RA patients.

133 lated in the sublining area of proliferating synovial tissue from RA patients.

134 in human and rabbit synovial fibroblasts and synovial tissue from rheumatoid arthritis (RA) patients.

135 Synovial tissues from 5 patients with rheumatoid arthrit

136 Synovial tissues from animals treated with targeted fuma

137 s the expression of CD40-downstream genes in synovial tissues from anti-citrullinated protein Ab-posi

138 ll genes were also significantly enriched in synovial tissues from arthralgia patients.

139 Synovial tissues from DA rats and DA.ACI(Cia25) rats obt

140 with real-time polymerase chain reaction on synovial tissues from day-32 ankles.

141 reactivity was assessed by immunostaining of synovial tissues from normal controls and from patients

142 ODF mRNA was detected by RT-PCR in whole synovial tissues from patients with RA but not in normal

143 and by activated T lymphocytes derived from synovial tissues from patients with RA.

144 erred them into NOD-SCID mice engrafted with synovial tissues from patients with rheumatoid arthritis

145 by immunohistochemistry using antibodies in synovial tissues from patients with rheumatoid arthritis

146 oducing predominantly GM-CSF are expanded in synovial tissues from patients with spondyloarthritis.

147 Synovial tissues from RA and osteoarthritis patients wer

148 ultured T cells with FLS lines isolated from synovial tissues from RA patients.

149 Through evaluation of synovial tissues from rheumatoid arthritis (RA) patients

150 naive B cells were significantly enriched in synovial tissues from UA, early RA, and established RA p

151 MD-1068, was added to primary cultures of RA synovial tissue, from which spontaneous cytokine release

152 ed with increased numbers of plasma cells in synovial tissue, greater numbers and activation of endot

153 Immunodepletion of fkn from five RA synovial tissue homogenates inhibited their ability to i

154 al cells and angiogenic activity found in RA synovial tissue homogenates.

155 ty in the rat cornea in vivo than did normal synovial tissue homogenates.

156 ed more IL-8 and ENA-78 compared with normal synovial tissue homogenates.

157 te receptor beta on activated macrophages in synovial tissue in a preclinical arthritic rat model.

158 ment of bare area regions with fibrovascular synovial tissue in joints without inflammatory changes.

159 moglobin content reflecting the hyperemia in synovial tissue in metacarpophalangeal (MCP) joints of 1

160 ally beneficial in facilitating apoptosis of synovial tissue in patients with RA.

161 Synovial tissue in rheumatoid arthritis is characterized

162 In-depth characterization of the synovial tissue in rheumatoid arthritis, as well as psor

163 ated mast cell degranulation in vitro and in synovial tissue in vivo.

164 ESE-1 is expressed in synovial tissues in RA and, to a variable extent, in OA,

165 ed the overexpression of wnt5a and fz5 in RA synovial tissues, in comparison to a panel of normal adu

166 Synovial tissue infections caused by L. pneumophila are

167 haracterize a newly identified population of synovial tissue-infiltrating natural killer (NK) cells o

168 Synovial tissue-infiltrating NK cells were evaluated for

169 In vivo, NMT1 loss caused robust synovial tissue inflammation, whereas forced NMT1 overex

170 similarly reduced, with less infiltration of synovial tissue into the underlying bone.

171 Immune-competent cell trafficking to synovial tissue is integral to the pathogenesis of RA.

172 by macrophages in rheumatoid arthritis (RA) synovial tissue is largely driven by contact-dependent a

173 e mechanism of this activation in rheumatoid synovial tissue is unknown.

174 that is characterized by hypertrophy of the synovial tissue, leukocyte infiltration, angiogenesis, a

175 IL-7 and IL-7R were coexpressed on RA synovial tissue lining and sublining macrophages and end

176 A significant decrease in synovial tissue lubricin gene expression was associated

177 in synovial fluid (SF) lavage specimens and synovial tissue lubricin gene expression were evaluated

178 Actin-normalized Western blot analysis of synovial tissue lysates confirmed the increased expressi

179 We hypothesized that synovial tissue macrophages (STM), which persist in remi

180 The reduction of synovial tissue macrophages is a reliable biomarker for

181 The inflamed microenvironment in the synovial tissue maintains responsiveness to IL-6 trans-s

182 es and growth factors elaborated by inflamed synovial tissues may contribute to osteoclast differenti

183 Thus, local production of EBV Ags in synovial tissues may not be the cause of the accumulatio

184 nd full-dose gadobenate dimeglumine-enhanced synovial tissue (mean: 914.35 +/- 251.1 vs 1022 +/- 244.

185 liferation, consistent with the hyperplastic synovial tissue observed in MPS patients.

186 n of Legionella pneumophila serogroup 4 from synovial tissue obtained from an 80-year-old female with

187 FLS were isolated from synovial tissue obtained from both diseased and nondisea

188 of the CD45+ mononuclear cell infiltrate in synovial tissue obtained from patients undergoing primar

189 Moreover, macrophages in synovial tissue obtained from patients with rheumatoid a

190 significantly increased arthritis severity, synovial tissue OC abundance, and bone erosion.

191 beta and TNFalpha mRNA, respectively, in the synovial tissue of DA.ACI(Cia10) congenic rats compared

192 we identified GAG-binding cells in inflamed synovial tissue of human patients with RA.

193 is revealed that the intimal lining cells of synovial tissue of inflamed joints of patients with rheu

194 tion, we have detected bacterial rRNA in the synovial tissue of late-stage RA and non-RA arthritis co

195 ipheral blood (PB), synovial fluid (SF), and synovial tissue of patients with RA as well as in the PB

196 t sites of chronic inflammation, such as the synovial tissue of patients with RA.

197 B19 DNA has been detected in studies in the synovial tissue of patients with rheumatoid arthritis, b

198 FLS were isolated from synovial tissue of RA patients and from DA rats and arth

199 CD4+CD28- T cells in peripheral blood and synovial tissue of RA patients were found to express NKG

200 ipheral blood (PB), synovial fluid (SF), and synovial tissue of RA patients.

201 of CMV and EBV was detectable by PCR in the synovial tissue of RA.

202 e in the synovial fluid of 1 patient and the synovial tissue of the other.

203 the liver and was found to be upregulated in synovial tissues of CIA mice.

204 Synovial tissues of inflamed joints contain cells expres

205 FLS obtained from the synovial tissues of patients with RA or osteoarthritis w

206 tudying the B lymphocytes that expand in the synovial tissues of patients with rheumatoid arthritis (

207 h mast cells (MCs) often are abundant in the synovial tissues of patients with rheumatoid arthritis,

208 ced ectopic GC formation, as observed in the synovial tissues of patients with rheumatoid arthritis.

209 been measured in plasma, synovial fluid, and synovial tissues of patients.

210 ri to infect multiple tissues, including the synovial tissues of the joints.

211 s, we have investigated the expression in RA synovial tissues of various embryonic growth factors fro

212 Lubricin mRNA expression levels in synovial tissue on days 4 and 7 after arthritis inductio

213 ies have not been identified previously from synovial tissue or fluid from arthritis patients.

214 gen (HLA)-DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope f

215 MTG were not found in healthy synovial tissue or the tissue of patients with undiffere

216 ere no differences in EBV gene expression in synovial tissues or peripheral blood when comparing RA w

217 (JRA) is a tumor-like expansion of inflamed synovial tissue, or pannus, which causes much of the joi

218 in-11 in the specific adhesion of FLS and in synovial tissue organization and behavior in health and

219 Using single-cell RNA sequencing and synovial tissue organoids, we found that NOTCH3 signalli

220 t component of the rheumatoid arthritis (RA) synovial tissue pannus.

221 expressed in RA compared with osteoarthritis synovial tissues, particularly in the CD68-negative, fib

222 thritis (RA) focusing on the contribution of synovial tissue pathology (synovitis) in determining div

223 Conditioned media from explant cultures of synovial tissue, periprosthetic soft tissue (interface m

224 se results indicate that SCL derived from RA synovial tissue play a role in promoting B cell survival

225 that these rearrangements could occur in the synovial tissues, presumably in pseudo-germinal centers,

226 Moreover, homogenates from RA synovial tissue produced significantly more chemotactic

227 c assessment, micro-computed tomography, and synovial tissue quantitative polymerase chain reaction a

228 RA synovial tissue RANTES (regulated upon activation, norma

229 vivo, we selected a model using whole human synovial tissue rather than isolated cells.

230 CRT citrullination in synovial tissue samples and cell cultures was determined

231 Synovial tissue samples from 32 (31%) of 104 patients wi

232 ls of active versus persistent infection and synovial tissue samples from patients with chronic Chlam

233 Peripheral blood, synovial fluid, and synovial tissue samples were obtained from patients with

234 Synovial tissue samples, obtained prior to fracture and

235 by 2-color immunohistochemistry analysis of synovial tissue samples.

236 We utilized the RA synovial tissue SCID mouse chimera system to examine hum

237 Using microdissected RA synovial tissue sections, we observed abundant p53 trans

238 ed proliferation of RASFs and hyperplasia of synovial tissue seen in RA synovium.

239 thritis (RA), and macrophages are reduced in synovial tissue shortly after initiation of TNF inhibito

240 Immunohistological sections of RA synovial tissue showed strong staining for B7-H3 on FLS.

241 both normal muscle biopsy specimens and JRA synovial tissue specimens.

242 was undertaken to examine its expression in synovial tissue (ST) and role in arthritis.

243 DNA was prepared from synovial tissue (ST) and several synovial fluid (SF) sam

244 n-1 (THBS1, alias TSP-1) expression in human synovial tissue (ST) during the resolution phase of chro

245 ction of key proinflammatory mediators in RA synovial tissue (ST) explants.

246 t, by proinflammatory factors produced by RA synovial tissue (ST) fibroblasts and macrophages, result

247 cular endothelial growth factor (VEGF) in RA synovial tissue (ST) fibroblasts, and the underlying sig

248 53 tumor suppressor gene is overexpressed in synovial tissue (ST) from patients with longstanding rhe

249 In rat AIA, synovial tissue (ST) macrophages, fibroblasts, endotheli

250 In a chimeric SCID mouse/human synovial tissue (ST) model, mice were engrafted subcutan

251 canases (aggrecanase-1 and aggrecanase-2) in synovial tissue (ST) or fibroblast-like synoviocytes (FL

252 Synovial tissue (ST) samples from 167 patients with oste

253 ined in 65 synovial fluid (SF) samples and 7 synovial tissue (ST) samples from 17 patients with antib

254 cytes, including monocyte/ macrophages, into synovial tissue (ST), but factors mediating the ingress

255 s overexpressed in rheumatoid arthritis (RA) synovial tissue (ST), few synoviocytes undergo apoptosis

256 mmation, including rheumatoid arthritis (RA) synovial tissue (ST), often contain high endothelial ven

257 mokine receptors on CD3+ T lymphocytes in RA synovial tissue (ST), RA SF, RA PB, and NL PB.

258 ound mononuclear cell (MNC) recruitment into synovial tissue (ST), thought to be due in part to tumor

259 We used an RA synovial tissue (ST)-SCID mouse chimera model to evaluat

260 kocytes leave the bloodstream and invade the synovial tissue (ST).

261 tion into inflamed rheumatoid arthritis (RA) synovial tissue (ST).

262 gulating CTGF gene and protein expression in synovial tissue, suggesting a link with the disease cour

263 was used to isolate CD4 T cells residing in synovial tissue T cell/B cell follicles.

264 Synovial tissue T cells and B cells cooperate in differe

265 Consistent with this phenotype, synovial tissue T cells responded to trans-signaling by

266 HLA-DRB1-matched synovial tissues that were infiltrated by T cells, macro

267 as TSG-6 was broadly detectable in arthritic synovial tissue, the highest level of TSG-6 was co-local

268 zation of pro-myelomonocytic U937 cells into synovial tissue transplanted into SCID mice.

269 In rheumatoid arthritis the synovial tissue undergoes marked hyperplasia, becomes in

270 In rat AIA, IL-4 reduces synovial tissue vascularization via angiostatic effects,

271 e production and degranulation by stimulated synovial tissue versus normal blood NK cells were evalua

272 IL-4 induced a reduction in synovial tissue vessel density, which was paralleled by

273 Synovial tissue was analyzed by immunohistochemistry for

274 unosorbent assay, and expression of TSG-6 in synovial tissue was assessed by immunohistochemistry.

275 y and K/BxN serum transfer-induced arthritic synovial tissue was defined using immunohistochemical st

276 xpression of IL-7 and IL-7R in RA and normal synovial tissue was demonstrated by immunohistochemistry

277 Follicular response in the spleen and in synovial tissue was determined by in situ immunohistolog

278 Cadherin 11 expression in rheumatoid synovial tissue was evaluated using immunohistochemistry

279 RA synovial tissue was examined by immunohistochemistry.

280 D130 was minimal in the SF, its level in the synovial tissue was high.

281 ollicular response both in the spleen and in synovial tissue was inhibited by anti-CXCL13 treatment.

282 DA.ACI(Cia10) congenic rat synovial tissue was more likely to preserve its normal h

283 RA synovial tissue was obtained from RA patients during joi

284 Microarray analysis of synovial tissue was performed and gene expression patter

285 Microarray analysis of synovial tissue was performed, and gene expression patte

286 ent of neutrophils into infected kidneys and synovial tissue was significantly higher in mice inocula

287 reased T cell and macrophage infiltration in synovial tissues was accompanied by reduced P-selectin e

288 Joints and synovial tissue were collected 32 days after the inducti

289 s, and at synovectomy, all results of PCR of synovial tissue were negative.

290 ured fibroblast-like synoviocytes (FLS), and synovial tissues were examined by immunohistology with a

291 ive, mononucleated or multinucleated, within synovial tissue) were also positive for a macrophage-spe

292 pidly cytokine inducible, up-regulated in RA synovial tissue, where it is cell-bound, and up-regulate

293 the migration of monocytes from blood to RA synovial tissue, where they differentiate into macrophag

294 CTMC) phenotype in both normal and arthritic synovial tissue, which expresses mMCP-4, -5, -6, and -7,

295 d in activated T lymphocytes derived from RA synovial tissue, which were expanded by exposure to anti

296 Synovial tissues with diffuse inflammatory infiltrates h

297 infiltrates had high levels of TSP2, whereas synovial tissues with ectopic germinal center reactions

298 Five synovial tissues with severe to mild lymphocytic infiltr

299 Migration of these cells to synovial tissue would result in the transgene being swit

300 paucity of apoptosis has been observed in RA synovial tissues, yet the mechanism remains unknown.