ライフサイエンスコーパス: systemic infection

1 otic tolerance in the spleen during a murine systemic infection.

2 issue damage in clinical scenarios of severe systemic infection.

3 ministration of BCG has been associated with systemic infection.

4 eck occurs at 48 h with few bacteria causing systemic infection.

5 tion and culminating with establishment of a systemic infection.

6 rophylaxis prevented febrile neutropenia and systemic infection.

7 ulence of P. aeruginosa in a murine model of systemic infection.

8 itical for controlling GBS dissemination and systemic infection.

9 protein that is rapidly cleaved following a systemic infection.

10 albicans virulence in two distinct models of systemic infection.

11 cess to target cells and tissues, leading to systemic infection.

12 ADAP) in promoting CD8 T cell responses to a systemic infection.

13 cystine as sources of nutrient sulfur during systemic infection.

14 1 cell responses provided protection against systemic infection.

15 s; however, it is an extremely rare cause of systemic infection.

16 ation on early pathogen invasion and chronic systemic infection.

17 usly shown to be a major virulence factor in systemic infection.

18 strains lacking a functional RgfA increased systemic infection.

19 significant influence on virus titers during systemic infection.

20 results in one genetic variant establishing systemic infection.

21 za virus, naive ferrets rapidly succumbed to systemic infection.

22 A) clone usa300 derived directly from murine systemic infectiON.

23 bZIP60 and bZIP28 serve to repress local and systemic infection.

24 Inoculation into either site causes systemic infection.

25 nthase in an NRAMP1(r) murine model of acute systemic infection.

26 expression of antiviral genes and prevented systemic infection.

27 s essential for MRSA virulence during murine systemic infection.

28 gen in pigs and humans that can cause severe systemic infection.

29 protective or a deleterious function during systemic infection.

30 ed for fungal virulence in a murine model of systemic infection.

31 rough the mediastinal lymph nodes to cause a systemic infection.

32 by the inflammatory mediators that accompany systemic infection.

33 oid and aneuploid progeny that may result in systemic infection.

34 s neoformans into the brain parenchyma after systemic infection.

35 e mechanisms that can help prevent local and systemic infection.

36 ive bacteria or Gram-positive bacilli during systemic infection.

37 in from toxic peripheral inflammation during systemic infection.

38 the onslaught of host immune response during systemic infection.

39 SARS-CoV-2 (COVID-19) is a systemic infection.

40 tility, seemingly counterproductive to rapid systemic infection.

41 ine, and have laboratory findings suggesting systemic infection.

42 nsive gene expression and restriction of TRV systemic infection.

43 identified that established higher risk for systemic infection.

44 rom asymptomatic latent infections to severe systemic infection.

45 cantly exacerbate pulmonary pathologies in a systemic infection.

46 ith the host gastrointestinal tract to cause systemic infection.

47 g allow us to use the eye as a window to the systemic infection.

48 ients, mounts immune responses, and prevents systemic infections.

49 ge of infections, including life-threatening systemic infections.

50 lonization, translocation, dissemination and systemic infections.

51 mans, from mucocutaneous to life-threatening systemic infections.

52 ing that they are not suitable therapies for systemic infections.

53 al blood and the propensity to both skin and systemic infections.

54 e the inflammatory response in patients with systemic infections.

55 rstanding of the role these microbes play in systemic infections.

56 en that causes pneumonia and soft tissue and systemic infections.

57 us responsible for chronic mucocutaneous and systemic infections.

58 tified, although it has been associated with systemic infections.

59 r being a primary source of cytokines during systemic infections.

60 intestinal illness and, occasionally, severe systemic infections.

61 atient compliance while avoiding the risk of systemic infections.

62 eservoir for innate antibiotic resistance in systemic infections.

63 sed to attack cells in immune defense during systemic infections.

64 prevents sustained hyper inflammation during systemic infections.

65 sociated with a diverse array of mucosal and systemic infections.

66 ive tracts, but also causes life-threatening systemic infections.

67 rging multi-drug resistant yeast that causes systemic infections.

68 ng fungi, few exposure events lead to severe systemic infections.

69 ype being hypercompetitive for commensal and systemic infections.

70 cosal infections to severe, life-threatening systemic infections.

71 e the likelihood of enteric bacteria causing systemic infections.

72 human gut, but also causes life-threatening systemic infections.

73 lbicans may spread to cause life-threatening systemic infections.

74 ly infected CD4(+) T cells, which reinitiate systemic infection after antiretroviral therapy (ART) in

75 sponses play an important role in preventing systemic infection after exposure to the virus.

76 ), promotes acute pulmonary inflammation and systemic infection after lung challenge with S. pneumoni

77 den or cytokine response in a mouse model of systemic infection (after intravenous inoculation) at th

78 larvae were observed which displayed intense systemic infection alongside widespread melanotic nodule

79 lence in mouse models of acute pneumonia and systemic infections, although they grow normally in cult

80 a key virulence factor for the induction of systemic infection and abortion in pregnant animals and

81 slocate across the intestinal tract, causing systemic infection and abortion in pregnant animals.

82 iological functions, including a key role in systemic infection and abortion induction in pregnant an

83 to small amounts of HCV, but do not develop systemic infection and acute liver disease.

84 ort a case of echovirus 18-associated severe systemic infection and acute liver failure in an adult h

85 r the host, where it proliferates and causes systemic infection and death.

86 ocess of cancer metastasis in the context of systemic infection and identify NETs as potential therap

87 roteins are strongly induced in the liver by systemic infection and in the intestine by bacterial col

88 roteins are strongly induced in the liver by systemic infection and in the intestine by bacterial col

89 Intrauterine and systemic infection and inflammation cause 30-40% of spon

90 O concentration in the exhaled breath during systemic infection and inflammation, and (ii) encourage

91 During systemic infection and inflammation, immune effector cel

92 bone marrow (BM) injury, transplantation, or systemic infection and inflammation.

93 e a protective role in both gut-centered and systemic infection and inflammation.

94 The response to systemic infection and injury requires the rapid adaptat

95 mutant encoding NS1-ESEV and NS1-138F caused systemic infection and killed mice more efficiently.

96 (-/-) mice with the same vectors resulted in systemic infection and lethal outcome for the majority o

97 nzyme is crucial for host protection against systemic infection and lung challenge by GBS.

98 In vivo mouse systemic infection and neutropenic thigh model experimen

99 PS), but the specific role that CPS plays in systemic infection and particularly abortion in animals

100 estion of contaminated foods and may lead to systemic infection and possible death, with an overall 2

101 cquired through tainted food and may lead to systemic infection and possible death.

102 Additionally, increased GBS systemic infection and preterm births were observed in M

103 serum, and human urine and in vivo in mouse systemic infection and pulmonary challenge models.

104 averse tissue barriers, disseminate to cause systemic infection and reach target organs.

105 nt and ineffective in the lungs but controls systemic infection and reduces the progression of second

106 of HAdV in the respiratory tract may precede systemic infection and require early intervention.

107 commandeers patrolling monocytes to mediate systemic infection and seed a persistent reservoir essen

108 ofin is efficacious in a mouse model of MRSA systemic infection and significantly reduces the bacteri

109 monopartite virus that is able to establish systemic infection and silencing of endogenous maize gen

110 UNV C1 determines how quickly mice can clear systemic infection and that this depended on the cellula

111 hesis that NESp could acquire capsule during systemic infection and transform into more virulent pneu

112 ently infected cells capable of reinitiating systemic infection and viremia.

113 of 349 amino acids of CP are dispensable for systemic infection and/or virion assembly, which is rare

114 aturity including necrotizing enterocolitis, systemic infections and bronchopulmonary dysplasia were

115 of this inhibitor for use in vivo to prevent systemic infections and cellular damage, such as that ca

116 syndrome) are associated with cutaneous and systemic infections and early-onset forms of periodontit

117 ococcus faecalis, long implicated in serious systemic infections and failure of root canal treatment,

118 We review here the most recent findings on systemic infections and inflammation complicated by oral

119 ing to initial EBV penetration that leads to systemic infection, and (ii) basolateral to apical trans

120 gnancy, and low calorie weight losing plans, systemic infections, and intensive physical effort.

121 is important for S. pneumoniae to establish systemic infections, and TacL represents a potential tar

122 ), and host related factors (age; coincident systemic infection; and organ dysfunction, especially he

123 e responses in check during establishment of systemic infection are not completely understood.

124 Systemic infections are mainly with Pneumocystis jirovec

125 However, these systemic infections are presumed to be a "dead-end" for

126 These studies imply that HIV achieves systemic infection as a consequence of a failure in host

127 a frequent, life-threatening complication of systemic infection associated with multiple organ damage

128 nistration of cognate glycolipids and during systemic infection but not following exogenous cytokine

129 Sts enzymes leads to profound resistance to systemic infection by C. albicans, such that greater tha

130 at Sts(-/-) mice are profoundly resistant to systemic infection by Candida albicans, with resistance

131 IgG also provides protection against systemic infection by E. coli.

132 for inhibition of neutrophil recruitment and systemic infection by hypervirulent GAS.

133 MET-1 may attenuate systemic infection by preserving tight junctions, thereb

134 (LysMcre) mice were also more susceptible to systemic infection by S Typhimurium than wild-type mice.

135 C57BL/6J mice are extremely susceptible to systemic infection by Salmonella Typhimurium because of

136 Systemic infection by the pathogenic yeast Candida albic

137 nhibition of anorexia prevented invasion and systemic infection by wild-type S.

138 al antigens and conferred protection against systemic infections by E. coli and Salmonella by directl

139 ling and protected mice against local and/or systemic infections by Streptococcus pyogenes, Streptoco

140 The term given to the severe pneumonia and systemic infection caused by Legionella bacteria is Legi

141 ntimicrobial treatment for typhoid, a severe systemic infection caused by the bacterium Salmonella en

142 hat dietary Mn levels dictate the outcome of systemic infections caused by Staphylococcus aureus, a l

143 Although Listeria monocytogenes can induce systemic infection causing spontaneous abortion, septice

144 Streptococcus iniae causes systemic infection characterized by meningitis and sepsi

145 yphimurium requires access to glucose during systemic infection, data on the need for lipid metabolis

146 ial results and experimental models, include systemic infections, deleterious metabolic activities, e

147 f plant xylem tissues and the development of systemic infections, deletion of the two biofilm-promoti

148 Bacterial pathogens causing systemic infections disseminate from the initial infecti

149 also known as San Joaquin Valley fever, is a systemic infection endemic to parts of the southwestern

150 ntical, co-housed Drosophila given identical systemic infections experience different outcomes, with

151 9-day-old (P9), rat pups are susceptible to systemic infection following gastrointestinal colonizati

152 ococcal infection and is required for lethal systemic infection following S. pneumoniae lung challeng

153 tions, with continued virion assembly and/or systemic infection found after extensive deletions are m

154 In this study, we demonstrate that systemic infection fundamentally modifies the traffickin

155 preeclampsia/eclampsia and postpartum acute systemic infection had the highest risk of VTE during th

156 suggest that adaptation during the course of systemic infection has implications beyond the level of

157 rus (CCoV) variants that are associated with systemic infections have been reported in the European U

158 Systemic infections have mortality rates of up to 90%, c

159 In multivariable analysis, systemic infection (hazard ratio [HR], 3.52; 95% CI, 1.9

160 is a common, life-threatening consequence of systemic infection; however, the underlying mechanisms t

161 Conversely, in systemic infection, hyperinflammation associated with M1

162 Reasons for isolated enterectomy included systemic infection in 11, gastrointestinal bleeding in 1

163 can inhibit neutrophil recruitment and cause systemic infection in a mouse model of skin infection.

164 he Hrp pathogenicity island, is required for systemic infection in apple.

165 We identified 151 genes essential for systemic infection in both mammalian and avian models, 9

166 lular bacterial pathogen that causes chronic systemic infection in domesticated livestock and poses a

167 e Gram-negative pathogens that cause chronic systemic infection in farm animals and zoonotic infectio

168 d to be strong and long-lasting, pointing to systemic infection in humans.

169 mine the clinical severity of disease during systemic infection in humans.

170 fer of B1a cells was protective during acute systemic infection in IL-10-deficient hosts.

171 urvival of A. baumannii in a lethal model of systemic infection in immunocompetent mice.

172 Candida albicans can cause systemic infection in immunocompromised individuals that

173 nistic yeast that can cause life-threatening systemic infection in immunocompromised individuals.

174 teritis in healthy individuals or a serious, systemic infection in immunocompromised patients and has

175 e that the FoMV infectious clone establishes systemic infection in maize inbred lines, sorghum (Sorgh

176 ll responses against Vif and Nef can prevent systemic infection in Mamu-B*08(+) RMs following mucosal

177 During early systemic infection in mice with serotype 1, large-colony

178 for efficient TVCV cell-to-cell movement and systemic infection in Nicotiana benthamiana and Arabidop

179 major fungal pathogen that frequently causes systemic infection in patients with compromised immunity

180 orne pathogen, efficiently spread and caused systemic infection in Ripk3-deficient mice while almost

181 to inhibition of neutrophil recruitment and systemic infection in subcutaneous infection of mice by

182 Tm) establishes systemic infection in susceptible hosts by evading the i

183 Moreover, simulation of a minor systemic infection in tumor-bearing, but not control, mi

184 ported by in vivo data from a mouse model of systemic infection in which NKKY101 cells led to higher

185 mmunodeficiency state and heightened risk of systemic infections in advanced liver disease.

186 It is able to cause systemic infections in animals as well as humans, usuall

187 sae and skin, but it causes life-threatening systemic infections in hospital settings in the face of

188 Salmonella causes grave systemic infections in humans and other animals and prov

189 en associated with superficial, visceral, or systemic infections in humans, other mammals, or cold-bl

190 Systemic infections in Melody valve-implanted patients w

191 rolled by the host immune system, preventing systemic infections in oysters, whereas the successful i

192 Thus, multimodality imaging of experimental systemic infections in real time indicates complex dynam

193 is of virulence-essential genes required for systemic infections in two different host species and pr

194 ithelium and biofilm formation, while during systemic infection, increased capsule is required to eva

195 tion on erythroid development and found that systemic infection induced anemia, splenomegaly, elevate

196 We tested if EPS could protect from systemic infection induced by S. aureus and found that E

197 Systemic infection induces conserved physiological respo

198 Thus, ECs catalyze the detection of systemic infection into demand-adapted granulopoiesis.

199 eling how mucosal exposure of HIV results in systemic infection is critical for the development of ef

200 immunodeficiency virus type 1 transmission, systemic infection is established by one or only a few v

201 SABU patients with these characteristics for systemic infection is warranted because a delay in diagn

202 However, the role of candidalysin in driving systemic infections is unknown.

203 ion of HIV-1, like many pathogens that cause systemic infection, is structured and differentiated wit

204 onellae in that it causes a life-threatening systemic infection known as typhoid fever.

205 mall group of Salmonella serovars cause this systemic infection, known as invasive nontyphoidal salmo

206 ontagious viruses infecting humans, causes a systemic infection leading to fever, immune suppression,

207 ortedly, are the bacterial pathogens causing systemic infections like gastroenteritis and typhoid fev

208 During murine systemic infection, LipA suppresses pro-inflammatory mac

209 antation within 12 weeks of baseline; active systemic infection; malignancy within the last 5 years;

210 have developed a Tubulinosema ratisbonensis systemic infection model in the genetically amenable Dro

211 In this study, we evaluated a systemic infection model of C. tropicalis, a clinically

212 more vascular disease in a zebrafish larvae systemic infection model over 72 h compared to those inj

213 Challenge of HlaH35L-immunized mice using a systemic infection model resulted in a limited, but stat

214 Here we established a novel zebrafish larvae systemic infection model showing that Pg rapidly adheres

215 In this article, we show in a systemic infection model that the major receptor for C5a

216 Compounds were screened in a murine systemic infection model to rapidly identify compounds w

217 bliniensis in the Galleria mellonella insect systemic infection model.

218 opment and survival of memory CD8 T cells in systemic infection models, we hypothesized that TSLP spa

219 de data supporting the in vivo efficacy in a systemic infection murine model setup with a drug-resist

220 However, systemic infections occur infrequently in healthy indivi

221 Consistent with these findings, efficient systemic infection of BrYV requires P0(Br) .

222 rally a mild and self-limited consequence of systemic infection of cardiotropic viruses.

223 nterica serovar Typhimurium causes a natural systemic infection of mice that models acute and chronic

224 It also is required to prevent systemic infection of mice with enteric bacteria.

225 We show that systemic infection of mice with Escherichia coli, common

226 during bacterial growth in vitro and during systemic infection of mice, and recombination creates ra

227 ng lipid metabolism genes were defective for systemic infection of mice.

228 ed as an important virulence determinant for systemic infection of Streptococcus iniae.

229 rus [BV]) is produced there, and BV mediates systemic infection of the animal.

230 essential step in establishing the efficient systemic infection of the entire plant.

231 ssues, confirmed that TuMV could establish a systemic infection of the plant by going through xylem v

232 We evaluated the system with experimental systemic infections of severe combined immunodeficiency

233 ibiotics for specific indications, confirmed systemic infection on culture, or endometritis.

234 g and cognitive function often occurs during systemic infection or inflammation.

235 their deletion causing no obvious effects on systemic infection or virion assembly.

236 ve either high oral bioavailability to treat systemic infections or low intestinal permeability to tr

237 on is required for high-level bacteremia and systemic infection, partly by disrupting lung epithelium

238 Mice were trained and subjected to systemic infections, peritonitis, enteritis and pneumoni

239 Mice were trained and subjected to systemic infections, peritonitis, enteritis, and pneumon

240 After hospitalization, remote-site invasive systemic infection related to DFU (DFU-ISI) may occur.

241 dophytes manage to establish their sustained systemic infection remains largely unknown.

242 Optimal protection following respiratory or systemic infection required a mixture of Abs that target

243 encapsulated strain WU2 in a murine model of systemic infection resulted in encapsulation of NESp and

244 may occur, ranging from mucosal to invasive systemic infections resulting in microbe-mediated and/or

245 daily risk threshold), with the exception of systemic infection risk from MAC exposure in some buildi

246 During systemic infection, Salmonella avoids NLRC4 inflammasome

247 Despite establishing a systemic infection, SNV differentially activated host re

248 secondary infections sometimes develop into systemic infections such as bacteremia.

249 nthracis exhibits a rapid growth rate during systemic infection, suggesting that the bacterium expres

250 e spirochete Leptospira interrogans causes a systemic infection that provokes a febrile illness.

251 biotic-resistant bacteria (ARB) are prone to systemic infections that are difficult to treat.

252 Listeria monocytogenes Within a few hours of systemic infection, the massive proliferation of L. mono

253 bacterium-fungus interaction is required for systemic infection, the mechanism by which bacteria diss

254 These results suggest that during systemic infection, the Salmonella Typhimurium that reli

255 from superficial mucosal to life-threatening systemic infections, the latter particularly in patients

256 function for the gut microbiota in combating systemic infection through the induction of protective I

257 We used a murine model of systemic infection to test the virulence of a PhoQ-defic

258 s is by shifting from a virulent lifestyle, (systemic infection), to a dormant carrier state.

259 Systemic infection triggers a spectrum of metabolic and

260 produce clinical manifestations ranging from systemic infection typhoid to invasive nontyphoidal Salm

261 ella including Salmonella Typhi which causes systemic infection, typhoid, in humans.

262 ll-depleted mice also developed disseminated systemic infection, unlike control infected mice.

263 tion to viral taxonomy, the ability to cause systemic infection was the strongest predictor of severe

264 Using an in vivo model of systemic infection, we demonstrated that the ability of

265 mouse models of intestinal colonization and systemic infection, we identified eight transcription re

266 Using a murine model of systemic infection, we observed tcyP-dependent competiti

267 ion to previously reported associations with systemic infection, which are reviewed herein, Lyme dise

268 We found that pulmonary but not systemic infection with a high-virulence strain of C. ne

269 eficiency or inactivation protects mice from systemic infection with a lethal dose of C. albicans, an

270 reby enhancing mutant mouse survival against systemic infection with a lethal dose of the pathogenic

271 By contrast, systemic infection with a murine cytomegalovirus (MCMV)

272 Sirpalpha(-)/(-) mice succumbed to systemic infection with attenuated Salmonella, possessin

273 ndancy of CD4(+) T cells for defense against systemic infection with C. albicans and have important i

274 mice, dectin-1 is essential for controlling systemic infection with C. albicans but appears to be re

275 Using a mouse model of systemic infection with C. albicans, we identified the S

276 ce was observed as host sensitivity to early systemic infection with Candida albicans and T cell-medi

277 The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be repli

278 that these memory responses protect against systemic infection with GAS.

279 Staphylococcus aureus causes severe systemic infection with high mortality rates.

280 onocytogenes is a foodborne pathogen causing systemic infection with high mortality.

281 ti-inflammatory and prosurvival roles during systemic infection with L. monocytogenes In our current

282 n preventing dissemination of VACV following systemic infection with large doses of virus, it is whol

283 sfusion (DST), we have previously shown that systemic infection with Listeria monocytogenes (Lm) mont

284 ly for the effector Th1 response to an acute systemic infection with Listeria monocytogenes (Lm).

285 Indeed, following systemic infection with Listeria monocytogenes, germ-fre

286 Systemic infection with murine cytomegalovirus elicited

287 This study investigated the effect of systemic infection with murine cytomegalovirus on the di

288 Indeed, systemic infection with purR mutants causes accelerated

289 25 million people annually and results from systemic infection with Salmonella enterica serovar Typh

290 However, mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathog

291 es isolated from mutant mice after secondary systemic infection with Staphylococcus aureus, suggestin

292 erse settings of glycolipid immunization and systemic infection with Streptococcus pneumoniae.

293 deficiency rendered mice more susceptible to systemic infection with the pathogenic bacterium group B

294 Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii

295 classic Whipple's disease (CWD), the chronic systemic infection with Tropheryma whipplei, immune reco

296 We find that systemic infections with a variety of pathogens trigger

297 Systemic infections with Gram-negative bacteria are char

298 Systemic infections with multidrug-resistant enterococci

299 control of gastrointestinal invasion during systemic infection, with dectin-1 deficiency associating

300 ebrates, wild-type flies contain C. glabrata systemic infections yet are unable to kill the injected