ライフサイエンスコーパス: systemic inflammation

1 y virus (HIV) and is associated with reduced systemic inflammation.

2 duals with lower SES showed higher levels of systemic inflammation.

3 the relationship between SES and markers of systemic inflammation.

4 cterial colonization and potentially reflect systemic inflammation.

5 failure (HF) is associated with measures of systemic inflammation.

6 hese mice spontaneously develop a severe and systemic inflammation.

7 d by ischaemia-reperfusion, toxic injury and systemic inflammation.

8 c UBA1 isoform homologue in zebrafish caused systemic inflammation.

9 anti-inflammatory molecules and increase in systemic inflammation.

10 esicles (OMVs) that are capable of mediating systemic inflammation.

11 notype of asthma associated with obesity and systemic inflammation.

12 -related asthma symptoms, albuterol use, and systemic inflammation.

13 acrophages to produce IL-1beta, thus driving systemic inflammation.

14 NT-proBNP, kidney function and of markers of systemic inflammation.

15 a-1-Acid glycoprotein at 15 mo characterized systemic inflammation.

16 critical cells for the control of local and systemic inflammation.

17 en shown to play important roles in limiting systemic inflammation.

18 serum cytokines were assessed as measures of systemic inflammation.

19 distinguish between sepsis and noninfectious systemic inflammation.

20 f foamy macrophages, hepatosplenomegaly, and systemic inflammation.

21 t few studies adjust for dietary intakes and systemic inflammation.

22 a proportion that correlates inversely with systemic inflammation.

23 umor and bone marrow glucose uptake and host systemic inflammation.

24 S with AMD is, at least in part, a result of systemic inflammation.

25 s, which may spread to produce more advanced systemic inflammation.

26 lerance and insulin sensitivity with reduced systemic inflammation.

27 of IL-6TS-inducible genes in the absence of systemic inflammation.

28 me have been linked to increased frailty and systemic inflammation.

29 isease of the cardiac muscle associated with systemic inflammation.

30 sm such as hyperthermia, endotoxemia, and/or systemic inflammation.

31 s of the antibiotics are driven by increased systemic inflammation.

32 omotes host-microbiota mutualism, preventing systemic inflammation.

33 tality in 48 to 72 h due to robust local and systemic inflammation.

34 ers (CCR1, MAPK14, ICAM1) leads to increased systemic inflammation.

35 the oral microbiota triggered by RA-induced systemic inflammation.

36 n ApoE(-/-)MHCII(-/-) mice indicated reduced systemic inflammation.

37 lleviating hepatic and renal dysfunction and systemic inflammation.

38 er activation is not limited to induction by systemic inflammation.

39 o accomplish this are nonspecific and elicit systemic inflammation.

40 infection-positive versus infection-negative systemic inflammation.

41 No changes were observed in systemic inflammation.

42 e actions of these statins on both joint and systemic inflammation.

43 in Apoe (-/-) mice by regulating lesion and systemic inflammation.

44 ted a significant decrease in >/=1 marker of systemic inflammation.

45 ease in exercise performance observed during systemic inflammation.

46 g the effect of prebiotics and synbiotics on systemic inflammation.

47 ficiencies in immune responses and increased systemic inflammation.

48 infected neutrophilic RA was associated with systemic inflammation.

49 is of neurological disorders following acute systemic inflammation.

50 rts protective actions reducing vascular and systemic inflammation.

51 levels, as well as reductions in airway and systemic inflammation.

52 ght loss, atrophy of adipose tissue (AT) and systemic inflammation.

53 nuated by adjustment for baseline markers of systemic inflammation.

54 is characterised by intermittent hypoxia and systemic inflammation.

55 ress, myocardial injury, renal function, and systemic inflammation.

56 cells and/or correcting dysbiosis to dampen systemic inflammation.

57 immunoassay (Olink) and used to recapitulate systemic inflammation.

58 ) has increasingly been linked to heightened systemic inflammation.

59 , clinical stage, and elevated biomarkers of systemic inflammation.

60 Normal aging is accompanied by escalating systemic inflammation.

61 s that could be associated to improvement in systemic inflammation.

62 otential reduction in LRNC with treatment of systemic inflammation.

63 lood vessels and are accompanied by aberrant systemic inflammation.

64 ely progressing brain dysfunction induced by systemic inflammation.

65 okine responses to restimulation, it reduced systemic inflammation.

66 a potential approach to treating the severe systemic inflammation.

67 toms during the course of a fever, a sign of systemic inflammation(1,2).

68 uman sepsis, old mice demonstrated low-grade systemic inflammation 14 days after cecal ligation and p

69 )-which comprises multiorgan dysfunction and systemic inflammation(2-13).

70 In the cecal ligation and puncture model of systemic inflammation, a dramatic decrease of cytokine p

71 stress has been widely proposed to increase systemic inflammation, a pathway that may link stress wi

72 Systemic inflammation accompanied by a "cytokine storm,"

73 brain perfusion, catecholamine release, and systemic inflammation after severe hemorrhagic shock in

74 Increasing evidence has suggested that systemic inflammation along with local brain inflammatio

75 ic inflammation.SIGNIFICANCE STATEMENT Acute systemic inflammation alters behavior and produces dispr

76 ion of CLEC-2 but not GPVI leads to enhanced systemic inflammation and accelerated organ injury in tw

77 -/-) microbiota into Ldlr(-/-) mice enhances systemic inflammation and accelerates atherogenesis.

78 the cytokine interleukin-6 in vivo prevented systemic inflammation and ameliorated clinical disease.

79 ed WT mice resulted in increased severity of systemic inflammation and appearance of sJIA-like sympto

80 d significantly ameliorates their underlying systemic inflammation and autoimmunity.

81 We hypothesized that obesity-related systemic inflammation and B-cell stress could exacerbate

82 tent with the notion that obesity-associated systemic inflammation and B-cell stress lowers the thres

83 ffer therapeutic opportunities to ameliorate systemic inflammation and brain injury after stroke.

84 dy), we found that albumin treatment reduced systemic inflammation and cardiocirculatory dysfunction

85 racteristics of the human disease, including systemic inflammation and cartilage dysplasia, but the m

86 inflammatory diseases, which cause low-grade systemic inflammation and contribute to several common c

87 We conclude that circulating LPS can promote systemic inflammation and contribute to the development

88 ociated with increased circulating levels of systemic inflammation and endothelial dysfunction biomar

89 e suppressing circulating CD4(+) T cells and systemic inflammation and enhancing tissue neovasculariz

90 neural substrate of cold-seeking behavior in systemic inflammation and expands the functional topogra

91 obiota configuration that is associated with systemic inflammation and has a high prevalence in loose

92 ween pediatric sepsis and infection-negative systemic inflammation and hence can potentially improve

93 ratio (MLR) are respectively associated with systemic inflammation and immune suppression and have be

94 Ss broadly to include life/organ-threatening systemic inflammation and immunopathology regardless of

95 sceral adiposity is strongly associated with systemic inflammation and increased cardiometabolic risk

96 SAVI patients present with early-onset systemic inflammation and interstitial lung disease, res

97 P) is a biomarker used clinically to measure systemic inflammation and is reproducibly increased in a

98 ets for intervention to suppress CKD-related systemic inflammation and its consequences.

99 lso assessed in two in vivo models including systemic inflammation and local brain inflammation.

100 protective factor in the CNS in response to systemic inflammation and may be a potential candidate f

101 ch from BHD to mOL-HDF significantly reduced systemic inflammation and miR-223 expression in plasma E

102 promising new treatment concept to decrease systemic inflammation and mortality of sepsis.

103 Biomarkers of intestinal and systemic inflammation and mucosal integrity were highly

104 t mice were protected from developing severe systemic inflammation and multi-organ injury following t

105 ndrome coronavirus-2 can induce uncontrolled systemic inflammation and multiple organ failure.

106 on cause of death in trauma due to excessive systemic inflammation and multiple organ failure.

107 al peripheral proinflammatory insult-induced systemic inflammation and normalized compromised blood-b

108 ease (iMCD) is a rare hematologic illness of systemic inflammation and organ dysfunction, with unknow

109 eing a mild self-limited illness to one with systemic inflammation and organ failure.

110 rdial infarction, stroke, and sepsis trigger systemic inflammation and organism-wide complications th

111 ulating inflammatory cytokines, may link the systemic inflammation and poor T cell function character

112 In addition to decreasing systemic inflammation and providing glycemic control wit

113 ggesting its role in nonatopic TH1-polarized systemic inflammation and pulmonary function deficits fo

114 dy was to determine the relationship between systemic inflammation and quality of life in patients wi

115 alarmin high mobility group box 1 protein in systemic inflammation and remote organ injury after trau

116 content in blood, thereby helping to reduce systemic inflammation and reverse insulin resistance.

117 asured C-reactive protein (CRP), a marker of systemic inflammation and risk of inflammatory disease,

118 Systemic inflammation and sarcopenia are easily evaluate

119 iting neuroinflammation through reduction of systemic inflammation and standardized neuroprotection p

120 a reciprocal relationship between low-grade systemic inflammation and stress exposure towards increa

121 Biomarkers of systemic inflammation and those for astrocyte and glial

122 otential for platelets in the development of systemic inflammation and thrombosis in SARS-CoV-2-infec

123 5), when systemically administered, triggers systemic inflammation and toxicity, with the liver being

124 amaging inflammatory cytokines, resulting in systemic inflammation and vascular dysfunction.

125 , we report that metabolic fasting increased systemic inflammation and worsened survival in experimen

126 variable and can include moderate to severe systemic inflammation and/or marked systemic immune supp

127 ced survival as well as reduced weight loss, systemic inflammation, and bacterial burden.

128 t the maintenance of the intestinal barrier, systemic inflammation, and glucose metabolism.

129 of 25(OH)D and PTH with beta-cell function, systemic inflammation, and kidney function apparently di

130 ng left ventricular and pulmonary pathology, systemic inflammation, and neurohormonal activation.

131 n transplants, and reaction to local injury, systemic inflammation, and regeneration.

132 with hydrocephalus, necrotizing cellulitis, systemic inflammation, and respiratory failure.

133 f breast tumours in dictating pro-metastatic systemic inflammation, and set the stage for personalize

134 cted third molars are associated with higher systemic inflammation, and their removal may represent a

135 ient deficiency risk independent of diet and systemic inflammation, and whether it mediates the relat

136 ociated altered metabolic profile, increased systemic inflammation, and, in men, poorer liver functio

137 s during TB-IRIS and their relationship with systemic inflammation are not fully understood.

138 sis and NAFLD the gut microbiota profile and systemic inflammation are significantly correlated and c

139 Using endotoxin-induced systemic inflammation as a model, we found that electroa

140 is evidence that there are other drivers of systemic inflammation as measured by CRP.

141 is evidence that there are other drivers of systemic inflammation as measured by CRP.

142 etaflammation refers to a chronic, low-grade systemic inflammation as opposed to the classical transi

143 as assessed on a patient-reported scale) and systemic inflammation (as shown by an elevated C-reactiv

144 Systemic inflammation associated with brain death (BD) d

145 tand the effects of psoriasis medications on systemic inflammation associated with cardiovascular ris

146 Septic shock is a systemic inflammation associated with cell metabolism di

147 in older adults, for example, it reduces the systemic inflammation associated with chronic age-relate

148 ry one, thereby resolving both the local and systemic inflammation associated with periodontal diseas

149 st that increases in FIB-4 may be reflecting systemic inflammation associated with poor outcomes.

150 hocyte ratio (NLR) is a desirable measure of systemic inflammation because it is easily calculated fr

151 cyte ratio (NLR) was used as an indicator of systemic inflammation before and after surgery.

152 hilic lipid-polymer conjugates that suppress systemic inflammation but provoke potent lymph-node immu

153 Hypertension induces systemic inflammation, but its impact on the outcome of

154 vasculature responds within minutes to acute systemic inflammation by upregulating the expression of

155 Systemic inflammation can affect the progression of some

156 Systemic inflammation can impair cognition with relevanc

157 ase 1 knockout (Trex1(-/-)) mice suffer from systemic inflammation caused largely by chronic activati

158 KSHV-MCD is characterized by systemic inflammation caused, in part, by lytic replicat

159 Early life, systemic inflammation causes long-lasting changes in beh

160 on caused maternal hypothermia, bradycardia, systemic inflammation, cervical dilation, intra-amniotic

161 lopathy with onset in infancy (SAVI) develop systemic inflammation characterized by vasculopathy, int

162 Trigeminal nerve stimulation also decreased systemic inflammation compared with the vehicle.

163 Rationale: Systemic inflammation compromises the reparative propert

164 Results: Using IL-10 knockout mice mimicking systemic inflammation condition, we compared therapeutic

165 ve suggested that dysregulated localized and systemic inflammation contributes to the development and

166 pulmonary bypass surgery (infection-negative systemic inflammation control subjects) was recruited.

167 c disorder characterized by lymphadenopathy, systemic inflammation, cytopenias, and life-threatening

168 olving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening

169 to pathogen dissemination and intestinal and systemic inflammation during the oral route of infection

170 Systemic inflammation, endothelial dysfunction, hepatic

171 In contrast, LPS-induced systemic inflammation enhanced Zip14-dependent zinc upta

172 reased LOY was associated with lower chronic systemic inflammation even after menopause.

173 All four had marked systemic inflammation, fever and fluctuating radiologic

174 Decoupling age-associated systemic inflammation from chronological aging by using

175 creased oral inflammatory load and increased systemic inflammation have an adverse effect on infant b

176 Links between microbial alterations and systemic inflammation have been demonstrated in chronic

177 play an important role in the regulation of systemic inflammation; however, the functional role of t

178 al complement complex levels and measures of systemic inflammation (i.e., CRP), cardiac function (i.e

179 ether with features of T-cell activation and systemic inflammation identified here support the view t

180 identify peripheral biomarkers representing systemic inflammation, impaired neuroprotection, and ast

181 BCG (BCG-Bulgaria, InterVax) vaccination on systemic inflammation in a cohort of 303 healthy volunte

182 RR) ligands, and investigating the course of systemic inflammation in a prospective cohort of acute a

183 type-1 agonist, attenuated hyperglycemia and systemic inflammation in diabetic endotoxemic mice.

184 imental diabetes increased hyperglycemia and systemic inflammation in experimental sepsis.

185 mmatory beta-glucans efficacy at attenuating systemic inflammation in health, and renal and vascular

186 M17- and nSMase2 gene expression attenuating systemic inflammation in health, and renal injury and ao

187 d support to a hypothesis implicating global systemic inflammation in HF with preserved ejection frac

188 nously, or per rectum; were on biomarkers of systemic inflammation in humans; and performed meta-anal

189 that plasmodial DNA is the primary driver of systemic inflammation in malaria, both within the phagol

190 tially ameliorates Treg cell dysfunction and systemic inflammation in O-GlcNAc deficient mice.

191 We inhibited systemic inflammation in old subjects by means of pretre

192 latory dysfunction, portal hypertension, and systemic inflammation in patients with decompensated cir

193 ith HF.CONCLUSIONThese findings suggest that systemic inflammation in patients with HF is causally li

194 s which improves dyslipidemia and markers of systemic inflammation in patients with Metabolic Syndrom

195 renine pathway of tryptophan metabolism, and systemic inflammation in people with HIV (PWH).

196 h several reports have documented heightened systemic inflammation in posttraumatic stress disorder (

197 Non-resolving systemic inflammation in TBDM comorbidity could reflect

198 hritis model and in IL-1beta- or LPS-induced systemic inflammation in vivo, IL-1R2(-/-) mice were cre

199 evidence supports the active involvement of systemic inflammation, in addition to local brain inflam

200 nd I-FABP correlated with several markers of systemic inflammation, including high-sensitivity C-reac

201 diated aTreg depletion resulted in increased systemic inflammation, increased inflammatory macrophage

202 It has been suggested that systemic inflammation increases the risk of age-related

203 Systemic inflammation independently predicts future card

204 Here we show that systemic inflammation, induced by bacterial LPS, produce

205 Whether systemic inflammation-induced acute dysfunction and acut

206 Thus "bioenergetic stress" drives systemic inflammation-induced dysfunction.

207 rols (n = 50), we measured parasite biomass, systemic inflammation (interleukin 6 [IL-6]), endothelia

208 sequential events during the advancement of systemic inflammation into the CNS and facilitate to und

209 Systemic inflammation is a hallmark of commonly encounte

210 Infection-triggered acute systemic inflammation is able to induce neuroinflammatio

211 Evidence of systemic inflammation is also present in some patients w

212 Systemic inflammation is increased in patients who devel

213 Systemic inflammation is known to increase the risk for

214 Chronic low grade systemic inflammation is linked to impaired lung functio

215 Systemic inflammation is present during and serves as a

216 Cancer-associated systemic inflammation is strongly linked to poor disease

217 In RA, systemic inflammation is thought to directly contribute

218 However, the origin of age-associated systemic inflammation is unknown.

219 well as an advocated in vivo model of acute systemic inflammation is unknown.

220 nt role of IL-1beta in controlling local and systemic inflammation, its overall regulation is still n

221 Systemic inflammation levels in Bact2-enterotyped indivi

222 erial dissemination from the oral cavity and systemic inflammation linked to IDT can induce a state o

223 nd platelet aggregation were impaired due to systemic inflammation, liver failure, anticoagulants (he

224 In addition to systemic inflammation, local arterial inflammation, driv

225 r1/Per2 is beneficial to counteract elevated systemic inflammation, lung tissue inflammation, and iro

226 These data aid our understanding of how systemic inflammation may augment the progression of neu

227 Systemic inflammation may influence trajectories of depr

228 We measured markers of systemic inflammation, monocyte activation, and gut inte

229 The systemic inflammation most likely occurs as a consequenc

230 Emerging evidence implicates airway and systemic inflammation, neuroimmune interactions, and eff

231 Emerging evidence implicates airway and systemic inflammation, neuroimmune interactions, as well

232 Neither maternal systemic inflammation nor placental (fetal) inflammation

233 on contributes to inflammatory arthritis and systemic inflammation not only in RA, but possibly also

234 fail to grow and die prematurely, displaying systemic inflammation, nutrient malabsorption and decrea

235 rily localized to skin lesions and lacks the systemic inflammation of moderate and severe disease.

236 Such 'leaky gut' conditions result in systemic inflammation, of which a hallmark is increased

237 distress syndrome (stage 3) associated with systemic inflammation often termed a "cytokine storm." B

238 = 0.23, p = 0.01) suggesting that actions of systemic inflammation on amygdala emotional reactivity p

239 our findings may suggest a different role of systemic inflammation on the risk of Parkinson disease c

240 atures: airway neutrophilia, obesity-related systemic inflammation, or in some cases, few signs of im

241 arterial endothelial function or stiffness, systemic inflammation, or lipid profile, but resulted in

242 matic adverse events, baseline intestinal or systemic inflammation, or vitamin D status.

243 We hypothesized that systemic inflammation per se can significantly prolong Q

244 ecent findings suggest that an overexuberant systemic inflammation plays a primary role in ACLF progr

245 porary antihyperglycemic agents, by reducing systemic inflammation postbariatric surgery, or by modul

246 In the absence of Spop, systemic inflammation proceeded in an unresolved manner,

247 The data suggest that acute systemic inflammation produces both reversible cognitive

248 impact of age on the overall changes in the systemic inflammation profiles in subpopulation of TB pa

249 During acute infections, systemic inflammation rapidly induces cytokine-mediated

250 Systemic inflammation reduced microglial clearance of am

251 Systemic inflammation, reflected by increased plasma con

252 clear magnetic resonance composite marker of systemic inflammation, reflects serum concentration and

253 e injured brain sends out signals to trigger systemic inflammation remains unclear.

254 as lipopolysaccharides (or endotoxin) cause systemic inflammation, resulting in a substantial global

255 hereas Ripk1(-/-) mice died postnatally from systemic inflammation, Ripk1(D325A/D325A) mice died duri

256 CE There is a slow yet significant uptick in systemic inflammation secondary to HIV infection that ha

257 port that caspase-8 is a central mediator of systemic inflammation, septic shock in the Plasmodium ch

258 nce microbial responsiveness while dampening systemic inflammation should be further explored for pot

259 Obese individuals with persistent low-grade systemic inflammation showed reduced leukocyte productio

260 Systemic inflammation (SI) is involved in the pathogenes

261 sms involved in hypothermia and fever during systemic inflammation (SI) remain largely unknown.

262 rved during lipopolysaccharide (LPS)-induced systemic inflammation (SI; at a septic-like model) in sp

263 rodent models of four common types of pain: systemic inflammation (sickness behaviour), post-surgica

264 havioral and cognitive consequences of acute systemic inflammation.SIGNIFICANCE STATEMENT Acute syste

265 h of these diseases are also associated with systemic inflammation, similar to HIV infection.

266 dy end points included changes in markers of systemic inflammation (soluble CD163 and CD14, and inter

267 Following this pulmonary and systemic inflammation, spinal cord injury-immune depress

268 oimmunity appears to cause catatonia less by systemic inflammation than by the downstream effects of

269 ection in vivo is characterized by extensive systemic inflammation that can exacerbate infection by p

270 Obesity is accompanied by low-grade systemic inflammation that etiologically contributes to

271 of dysregulated immunometabolism and chronic systemic inflammation that intensifies virally induced h

272 Sepsis is characterized by systemic inflammation that is caused by infection and by

273 cline of barrier integrity and the resulting systemic inflammation that occurs with aging.

274 on in the early phase after fracture reduced systemic inflammation, the recruitment of immune cells,

275 n is associated with platelet hyperactivity, systemic inflammation, thrombotic complications, and coa

276 Systemic inflammation through persistent monocyte activa

277 oluble cytokine that is directly involved in systemic inflammation through the regulation of the intr

278 ed carbon nanotubes (MWCNTs) causes indirect systemic inflammation through unknown pathways.

279 rate that deregulated necroptosis results in systemic inflammation, tissue fibrosis, and autoimmunity

280 Further study is needed to determine whether systemic inflammation truly drives SIRS in this populati

281 nregulation of adipocytokines and markers of systemic inflammation underlies vitamin D effects.

282 regulatory role for NK cells in CFA-induced systemic inflammation via a NKG2D-dependent control of a

283 Systemic inflammation was also associated with increased

284 Overall, systemic inflammation was directly linked to increased d

285 Systemic inflammation was lost on expression of a non-se

286 d prior to Il1b detection in the brain, when systemic inflammation was minimal.

287 Systemic inflammation was mitigated by propionate treatm

288 hile in mice IL-7 is known to play a role in systemic inflammation, we found that in humans IL-7 also

289 Circulatory dysfunction and systemic inflammation were extremely unstable in many pa

290 The T cell-instructed IL-1beta resulted in systemic inflammation, whereas absence of TNFR or Fas si

291 most consistent with ICANS as a syndrome of systemic inflammation, which affects the brain through c

292 ng of sleep disturbance-induced increases in systemic inflammation, which can be viewed as an early e

293 homeostasis and the development of low-grade systemic inflammation, which increase the risk to develo

294 In addition, OSAS is considered as low-grade systemic inflammation, which is associated with a higher

295 el of endometriosis, IL-33 injections caused systemic inflammation, which manifested as an increase i

296 ng with acute severe respiratory failure and systemic inflammation who received either standard-of-ca

297 age, ineffective lung repair mechanisms, and systemic inflammation with associated organ dysfunction.

298 Systemic inflammation with high levels of pro-inflammato

299 They showed systemic inflammation with high levels of serum proinfla

300 We statistically link early systemic inflammation with later local increases in infl