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1 ded protein response (UPR), is mediated by a tRNA ligase.
2  biosynthesis; the other is in thrS, the Thr-tRNA ligase.
3 yme generates ends that are spliced by yeast tRNA ligase.
4 that has a site-specific RNase activity, and tRNA ligase.
5 ) at the splice junction generated by fungal tRNA ligase.
6 es an internal RNA 2'-phosphate generated by tRNA ligase.
7 f how RNA substrates are recognized by 3'-5' tRNA ligases.
8 knock-out, we find no evidence for disrupted tRNA ligase activity, as measured via XBP1 splicing, in
9 ivity of EPRS1, without inhibiting canonical tRNA ligase activity, provides a therapeutic approach po
10 C1 mRNA occurs by a novel pathway, involving tRNA ligase and bypassing the spliceosome.
11  this class of enzymes, which includes yeast tRNA ligase and trypanosome RNA-editing ligases.
12 ducts such as ammosamides, peptide-aminoacyl tRNA ligases append amino acids to the C-terminus of a r
13               Our findings draw attention to tRNA ligase as a promising drug target.
14  spliced by a unique mechanism that requires tRNA ligase but not the spliceosome.
15 yrosyl-tRNA synthetase (YARS1) and six other tRNA ligases cause Charcot-Marie-Tooth peripheral neurop
16                     The addition of purified tRNA ligase completes splicing; we therefore have recons
17 oa, RtcB functions as part of a five-subunit tRNA ligase complex (tRNA-LC) along with Ddx1, Cgi-99, F
18                                          The tRNA ligase complex (tRNA-LC) splices precursor tRNAs (p
19 ular architecture and mechanism of the human tRNA ligase complex and provide a structural framework f
20 port that RTCB, the catalytic subunit of the tRNA ligase complex, and its co-factor archease mediate
21     Among them are several components of the tRNA ligase complex, which we show regulate SARS-CoV-2 i
22 ure of the purified five-subunit Danio rerio tRNA ligase complex.
23 ing ligases and architecture of the metazoan tRNA ligase complex.
24 ing FAM98B, a component of the transfer RNA (tRNA) ligase complex (tRNA-LC) that harbors the most gly
25  and for the functional complementation of a tRNA ligase-deficient Saccharomyces cerevisiae strain in
26 where it erases the 2'-PO4 mark installed by tRNA ligases during tRNA splicing.
27 ciated by base pairing, and exon ligation by tRNA ligase follows the same chemical steps as for pre-t
28                                              tRNA ligases have alternative functions in RNA repair an
29 of arginine and tryptophan, and for arginine tRNA ligase, have shorter divergence times than the unde
30                   Unlike the yeast and plant tRNA ligases involved in tRNA splicing, Bf RNL lacks hea
31 ma-toxin because the sealing domain of yeast tRNA ligase is unable to rectify a break at the modified
32 eaves HAC1 mRNA at both splice junctions and tRNA ligase joins the two exons together.
33 specific mutation in the C. capitata lysine--tRNA ligase (Lysyl-tRNA synthetase, LysRS) gene responsi
34    During this process, a peptide-amino acyl tRNA ligase (PEARL) adds amino acids to the C-terminus o
35 dent manner catalyzed by a PEptide Aminoacyl-tRNA Ligase (PEARL).
36 peptide aminoacyl-transfer ribonucleic acid (tRNA) ligase (PEARL) first loads an amino acid to the C
37 ontinuing discovery of new peptide-aminoacyl-tRNA ligases (PEARLs) has unveiled a diverse array of en
38  and four enzymes known as PEptide Aminoacyl-tRNA Ligases (PEARLs).
39 g of the 5' termini of linear introns by the tRNA ligase Rlg1 and destruction by the cytoplasmic tRNA
40  presence of ectopic RtcB, yeast lacking the tRNA ligase Rlg1/Trl1 are converted into producing tricR
41 n fragments that are subsequently ligated by tRNA ligase (RLG1).
42 sed of the kinase-endonuclease Ire1p and the tRNA ligase Rlg1p, was activated.
43 archaea, the genes encoding Archease and the tRNA ligase RtcB are localized into an operon.
44 niae depends in part upon MurM, an aminoacyl-tRNA ligase that attaches L-serine or L-alanine to the s
45             We have identified a mutation in tRNA ligase that disrupts the UPR in the yeast Saccharom
46                                            A tRNA ligase then incorporates this phosphate into the in
47 quires an endonuclease to excise the intron, tRNA ligase to join the tRNA half-molecules, and 2'-phos
48 t lack the endogenous "healing/sealing-type" tRNA ligase Trl1.
49 ndent RNA ligase family that includes fungal tRNA ligase (Trl1) and a putative baculovirus RNA ligase
50                                        Yeast tRNA ligase (Trl1) converts cleaved tRNA half-molecules
51                                        Yeast tRNA ligase (Trl1) is an essential enzyme that converts
52                                       Fungal tRNA ligase (Trl1) is an essential enzyme that repairs R
53                                        Yeast tRNA ligase (Trl1) is an essential trifunctional enzyme
54                                       Fungal tRNA ligase (Trl1) rectifies RNA breaks with 2',3'-cycli
55                     Fungal, plant, and phage tRNA ligases use different strategies to discriminate th