ライフサイエンスコーパス: tackle

1 the complexity to be faced and how it may be tackled.

2 yl-hydroxytoluene (BHT) at 20 and 800ppm was tackled.

3 e well acknowledged practical problems to be tackled.

4 otostimulation with high cell specificity to tackle a long-standing debate regarding the existence of

5 gh-volume environmental data requires one to tackle a series of challenges associated with the typica

6 Therefore, this work tackles a characterization analysis of the lignocellulos

7 Our study tackles a long-standing gap in the monarch's annual cycl

8 allow a full "reboot" of NRT methodology for tackling a broad range of chemical applications, includi

9 This policy matrix also offers a tool for tackling a broader class of illicit online behaviours(21

10 ting that either may be equally effective in tackling a hand-eye coordination task with complex targe

11 f hydraulic structures is a common method of tackling adverse effects of turbidity currents.

12 ting relevant pathogenicity prediction tools tackle all non-coding variants as one amorphic class and

13 Since the issue has been tackled almost exclusively by macroscopic techniques so

14 in Alzheimer's disease, but it should not be tackled alone rather together with other key targets to

15 To tackle AMR effectively, better diagnostic tests must be

16 ions of these techniques and how they can be tackled and discuss how these novel approaches can assis

17 ommunity pharmacies as an important task for tackling antibiotics resistance and planned to eliminate

18 se antimicrobials, offering a strong tool to tackle antimicrobial resistance, a serious global health

19 ening governance is an essential strategy to tackling antimicrobial resistance (AMR) at all levels: g

20 ney diseases are particularly challenging to tackle because they are pathologically diverse and are o

21 e complex image analysis methods, facilitate tackling biological problems previously impossible to st

22 le-duty actions, which aim to simultaneously tackle both undernutrition and problems of overweight, o

23 Here, we introduce MS2LDA+ that tackles both above-mentioned problems.

24 ation and challenges of epigenome editing to tackle brain disorders.

25 This challenge may be tackled by forming composite structures comprising a met

26 ce suggest that it could be more efficiently tackled by molecules directed toward different dysregula

27 hallenge, which the scientific community has tackled by mounting extensive global collaborations, com

28 ftware can tackle problems that could not be tackled by previously developed packages.

29 Currently, efforts to tackle C. quinquefasciatus vectored diseases are based o

30 rugs may be responsible for their ability to tackle cancers and for the side-effects caused by the dr

31 of alternative energy sources is crucial to tackle challenges encountered by the growing global ener

32 for efficient computational approaches that tackle challenges in large-scale data analysis and manag

33 (4 and 5) that include many new features to tackle challenges with increasingly complex macromolecul

34 Given the importance and demand for tackling challenges in antimicrobial resistance, the pro

35 diseased tissues could be a new strategy for tackling challenges in disease diagnosis and treatments

36 port hierarchical planning, enabling them to tackle challenging problems by breaking them down into s

37 s) offer new ways to address disease through tackling challenging targets and with greater potency, e

38 A solution that proved useful in tackling challenging targets is the use of electrophiles

39 oods and beverages is seen as one measure to tackle childhood obesity and is under active considerati

40 om a data scientist might still be needed to tackle class imbalance-a common challenge in ML classifi

41 tion (REDD+) is one of the major attempts to tackle climate change mitigation in developing countries

42 ions that can be taken by neuroscientists to tackle climate change.

43 ibitors, and traditional Chinese medicine to tackle colistin resistance.

44 allow for enhancement of their attributes to tackle complex diseases, not usually amenable to convent

45 a generic platform of technical solutions to tackle complex medical challenges.

46 s are being more frequently used together to tackle complex problems in structural biology.

47 thods, it is imperative that this problem is tackled computationally.

48 that simultaneously reduces ivory demand and tackles corruption and poverty.

49 researchers and engineers concerning how to tackle COVID-19 via rapid testing, mainly through nuclei

50 create value by leveraging corporate data to tackle crucial business problems.

51 as well as provide alternative approaches to tackle current problems, and open up new opportunities,

52 sychiatric disorders at a scale necessary to tackle daunting levels of polygenicity.

53 tions for both the design of serosurveys and tackling dengue in Bangladesh.

54 Because both approaches tackle different problems, both have different limitatio

55 ists who previously worked independently, to tackle discipline-specific challenges associated with co

56 letely upended how today's cancer biologists tackle drug target discovery.

57 -limitation and highlights the importance of tackling ecological questions from a geographical perspe

58 orms and crowdsourced community responses in tackling emerging plant diseases.

59 nimals collectively form complex patterns to tackle environmental difficulties.

60 allow us to propose research priorities for tackling environmental and socioeconomic challenges in t

61 This work also suggests that tackling EV molecular alterations secreted into intersti

62 sponse and help develop better strategies to tackle foodborne staphylococcal infections.

63 Here, we describe a tool that tackles four core phenotyping tasks: classification of c

64 full complexity of biological systems and to tackle fundamental challenges in life sciences.

65 a multivariate reaction norm model (MRNM) to tackle genotype-covariate (G-C) correlation and interact

66 d single-cell RNA-sequencing technologies to tackle glioblastoma's heterogeneous nature, providing ne

67 gnostic, prognostic and therapeutic tools to tackle glioblastomas is urgently needed.

68 r the design of next generation materials to tackle global energy and environmental challenges.

69 services are urgently needed to prevent and tackle harms from liver disease.

70 CV treatment should be evaluated in order to tackle HCV transmission among PWID.

71 rotein would be effective approaches towards tackling HD as well as other similar neurodegenerative d

72 This is particularly relevant to tackle health care accessibility inequality, which is no

73 This is the challenge that we tackle here: combining experimental and modeling studies

74 s and case-control models are suboptimal for tackling heterogeneity.

75 titial Lung Disease (ILD) patterns, few have tackled ILA, which likely precedes the development ILD i

76 tive, we highlight meritorious examples that tackle important issues from contemporary organic synthe

77 en rely on well-established model systems to tackle important questions.

78 ith deep learning is a promising approach to tackle important sequential decision-making problems tha

79 llenges that their communities are poised to tackle in the near future.

80 unctions, which are the two concepts that we tackle in this paper.

81 ies to reduce inequalities in adult BMI that tackle inequality with respect to both childhood and adu

82 stems, which have to date largely focused on tackling infectious diseases and maternal, neonatal, and

83 combining molecular orbital and VB theory to tackle interesting and challenging mechanistic questions

84 phils are important innate immune cells that tackle invading pathogens with different effector mechan

85 borders are now increasingly prioritized for tackling issues of global concern.

86 ditional generative adversarial networks for tackling it.

87 This, in turn, impedes our ability to tackle key biological questions that pertain to variatio

88 ment of genes from them can provide means to tackle key pests like H. armigera.

89 otein structure prediction and design toward tackling key biological questions and engineering challe

90 based system as a means to aid physicians in tackling large amounts of data, augmenting diagnostic ev

91 Here, we study mouse skin embryogenesis to tackle m6A's functions and physiological importance.

92 Tackling MARCKS-PIP3 circuit attenuates fibroblast activ

93 Tackling membrane wetting is an ongoing challenge for la

94 havioral tagging with novelty can be used to tackle memory problems observed in children and adolesce

95 psules, for example offering inspiration for tackling metals exhibiting high valence states such as i

96 boost in cognition, enabling individuals to tackle more complex (industrial) problems.

97 hlighting examples of double-duty actions to tackle multiple forms of malnutrition.

98 This formulation tackles multiple physiological barriers on-demand with a

99 A1 and ABCA7), they might be cornerstones to tackle neurodegenerative diseases.

100 ate brain-adipocyte interactions in order to tackle obesity and its comorbidities, as the precise con

101 as an important period for interventions to tackle obesity in the young to maximise long-term vascul

102 ing their consumption as part of measures to tackle obesity.

103 disease and highlight important questions to tackle onward.

104 Natural evolution tackles optimization by producing many genetic variants

105 Our approach can serve as a blueprint for tackling other eruptive forest insects.

106 lopment of tailored next-generation drugs to tackle P. gingivalis.

107 or without proceeding formal skin testing to tackle penicillin allergy efficiently within complex hea

108 e development of therapeutic strategies that tackle persistence in bacterial infections.

109 obal yield losses and greater local impacts, tackling plant pathogens is an ethical imperative.

110 ally validated an easy-to-handle strategy to tackle poor reproducibility in single-laboratory studies

111 ew generation of natural product chemists to tackle powerful undeveloped scaffolds.

112 dwelling parasitic worms, which is currently tackled primarily by mass administration of the drug pra

113 ata," it offers epidemiologists new tools to tackle problems for which classical methods are not well

114 Our software can tackle problems that could not be tackled by previously

115 s been suggested to possess a great value to tackle protein aggregation toxicity and neurodegenerativ

116 aths ensures a strong workforce that able to tackle public health issues.

117 Such approaches cannot tackle questions requiring knowledge of ultrastructure b

118 latory molecules as putative drug targets to tackle relapse to drug taking.

119 Tackling relapsing Plasmodium vivax and zoonotic Plasmod

120 gress in its prevention, more can be done to tackle risks of its development in the community and in

121 est that Thapsigargin could be repurposed to tackle S. aureus host cell infection in combination with

122 This work provides clues to tackle selectively cellular processes involved in neurod

123 rgeting of tissues by magnetic particles has tackled several limitations of traditional drug delivery

124 Through cooperation, we can tackle shared problems like climate change or pandemics

125 Thus, large-scale meta-analyses only tackle single terms that occur frequently.

126 pette aspiration, a problem not successfully tackled so far.

127 ic health needs to continue to, for example, tackle social inequalities in dental health, develop bet

128 Treatment and control programmes tackling soil-transmitted helminth (STH) infections requ

129 cuss the potential of the mechanical bond to tackle some of the classic problems of SWNT chemistry.

130 ure of the tumor microenvironment (TME), and tackling spatial heterogeneity in neoplastic metabolic a

131 he SPL via small-molecule modulators able to tackle splicing-associated diseases by altering/obstruct

132 in need, together with sustained efforts to tackle stigma and discrimination.

133 rategy for cardiac patients that attempts to tackle stress and psychosocial wellbeing, but it is unde

134 esents the identification of a new target to tackle striatal dysfunction associated with the D(2)R, s

135 ng pressure of flexible MOFs is developed to tackle such a challenge.

136 To tackle the above shortcomings, this paper reports on an

137 ifted its primary concern from attempting to tackle the apparent epidemic of noncommunicable diseases

138 opriate archiving and sharing approaches, to tackle the big data issues presented by biologging.

139 nd emerging polypharmacology approach rarely tackle the challenge of multi-indication drug design.

140 n order to develop recommendations on how to tackle the challenges associated with treating (micro)me

141 s should gain skills across these domains to tackle the challenges posed to us.

142 In order to tackle the challenges related to selectivity, activity,

143 proposed herein is thus able to successfully tackle the challenging problem of interface electrochemi

144 select and fuel indigenous microorganisms to tackle the commingled contamination of dioxane and chlor

145 the massively parallel approaches needed to tackle the complexity of human tissue.

146 he first time in China in February, 2020, to tackle the coronavirus disease 2019 (COVID-19) outbreak.

147 iron could be a promising future strategy to tackle the development and progression of chronic wounds

148 s to increase beta-cell number must not only tackle the difficult challenge of enticing a quiescent c

149 eatment, to improve patient outcomes, and to tackle the global threat of resistant bacteria that caus

150 s unique combination of enabling features to tackle the grand challenges in pressure- and tactile-sen

151 for prevention, health care, and research to tackle the growing challenge of neurological disorders.

152 compartment, they often fail to effectively tackle the HIV reservoir in the brain because of ineffic

153 Advancing interventions to tackle the huge global burden of hepatitis B virus (HBV)

154 nalisation has become a standard approach to tackle the information overload problem.

155 We tackle the intensive computations of dense signed networ

156 Here, we tackle the issue by combining high-quality time allocati

157 f harsh environmental conditions in order to tackle the issue of food security under the threat of cl

158 mends engaging multisectoral stakeholders to tackle the issue.

159 cording (GCaMP-mediated) and pupillometry to tackle the linkage between brain-state changes and neura

160 nd historical weather records can be used to tackle the longstanding problem of predicting cultivars'

161 eLife, like the rest of science, must tackle the many inequalities experienced by Black scient

162 Here, we tackle the mechanism of reduction of U(VI) by the mixed-

163 control body weight and a promising tool to tackle the obesity epidemic.

164 gy introduces several technical novelties to tackle the OCT frame misalignment, correct positioning o

165 Amongst the various approaches attempting to tackle the pathological features of synucleinopathies, a

166 To tackle the problem of antimicrobial resistance (AMR) sur

167 To tackle the problem of discriminating functional oligomer

168 ssessing variants for their pathogenicity to tackle the problem of increasing variants of unknown sig

169 In order to tackle the problem of persistence of infections that con

170 Here, we tackle the problem of spatially heterogeneous heat distr

171 s experience offers useful lessons on how to tackle the problem of stunting under differing scenarios

172 Then, we tackle the problem of trajectory classification of arbit

173 eity problem, where two different approaches tackle the problems.

174 Here we tackle the question of how cells process combinatorial s

175 Third, we tackle the question of whether intentionality, extended

176 encing data of airway biopsies are needed to tackle the question.

177 research on CMAM should carefully assess and tackle the remaining barriers that prevent AM cases from

178 refined as emerging technology allows us to tackle the remaining questions surrounding PG biosynthes

179 In this paper, we tackle the same problem by posing it as a Bayesian model

180 To tackle the second issue, we verbally indicated the locat

181 harmacological chaperones that target FAH to tackle the severe disease HT1.

182 and portable diagnostics hold the promise to tackle the spreading of diseases and decentralising heal

183 How we tackle the sudden emergence of ecosystem-wide degradatio

184 babilistic eQTL annotations to delineate and tackle the unique challenges arising in TWAS.

185 ctional approaches that are being applied to tackle the V2F problem for blood cell traits, illuminati

186 s fall short in providing the flexibility to tackle the varied challenges researchers face in such an

187 One, a unifying approach, tackles the comorbidity problem by assuming that a singl

188 This approach tackles the different chemical pathways for melanoidin f

189 Another, a multifactorial approach, tackles the heterogeneity problem by assuming that disor

190 Therefore, this method that simultaneously tackles the operational stability and lead contamination

191 tem components offer a promising context for tackling the challenges of working at the Top.

192 It offers state-of-the-art approaches to tackling the challenges that are unique to human in vitr

193 mise these ingenious coloured nanostructures tackling the current performance of organic matter in cu

194 provides a unified conceptual framework for tackling the distinct risks associated with fast, slow a

195 However, additionally tackling the drivers of land-use change could avoid conf

196 ogether, these data suggest a novel means of tackling the frequently intractable neurological consequ

197 biotic prescribing and thus a novel route to tackling the global challenge of AMR.

198 continued breastfeeding, may be critical to tackling the growing obesity epidemic.

199 omorbidities represents an important task in tackling the growing personal and societal burdens assoc

200 Oncology nurses are at the heart of tackling the increasing global burden of cancer.

201 By tackling the intrinsic chemical/electrochemical issues,

202 ach in drug design is a powerful strategy in tackling the multifactorial nature of Alzheimer's diseas

203 Tackling the pressing sustainability needs of society wi

204 cted P. vivax transmission by simultaneously tackling the reservoir of P. falciparum and P. vivax inf

205 of 2D perovskites is a promising approach to tackling the stability and voltage issues inherent in pe

206 rventionist, and specialised approach is not tackling the underlying causes of disease and is not add

207 ded the concentration of expertise needed to tackle their characteristic clinical problems and improv

208 problems that may be encountered and how to tackle them by what we term "rational vaccine design." W

209 ultidisciplinary problem-solving approach to tackle them.

210 Thus, an attractive way of tackling them is through efficient heuristics with prova

211 f the threats and lack of enough progress in tackling them to date, opportunities exist to change fut

212 e study the challenges and potential ways of tackling them to reveal the underlying mechanisms and tr

213 entire body and develop new nanocarriers to tackle these barriers.

214 induction for human activity recognition to tackle these challenges and constraints.

215 In order to tackle these challenges and improve resolution, a large

216 We propose to tackle these challenges with Parallelized Split Merge Sa

217 Healthcare providers are ill-prepared to tackle these challenges, as well as specific needs such

218 To tackle these challenges, we created GenTree, an integrat

219 To tackle these critical issues, a BBB-permeable biomimetic

220 f targeted therapeutically, could be used to tackle these currently untreatable infections.

221 multimodal approaches have been attempted to tackle these issues and have pushed the cycle stability

222 ation of epidemiologists and prepare them to tackle these issues of the 21st century.

223 With ongoing efforts to tackle these issues, as well as increasing awareness of

224 r-based nanoparticles have been developed to tackle these issues, but such strategies often fail to e

225 To tackle these issues, we have previously developed GRASP

226 logy as well as natural product isolation to tackle these problems and with those who possess a clear

227 To tackle these problems, we present an interpretable and e

228 Here, we tackle these questions in the context of decisions about

229 To tackle these questions, we carried out a series of behav

230 To tackle these questions, we generated new transcriptomes

231 ive regulation and legislation are needed to tackle these shared risk factors.

232 To tackle these shortcomings, a novel sorbent material was

233 eld carcinogenesis and propose directions to tackle these voids using single-cell-based approaches an

234 This study tackles these issues by examining the relative value of

235 an inefficient health system is a barrier to tackling these challenges among such a rapidly aging pop

236 We review how contemporary approaches are tackling these challenges and will ultimately serve as a

237 dings may help to inspire future research in tackling these inequalities and highlight the need for c

238 Tackling these issues successfully is dependent on acqui

239 size of nematodes make them advantageous for tackling these problems [4-6].

240 Tackling these problems will benefit from a more explici

241 The difficulty in therapeutically tackling these viral systems stems in part from their re

242 To tackle this analytical challenge, we developed a CI inte

243 nal organizations and civil society, need to tackle this aspect in a concerted effort.

244 ategies have been developed in an attempt to tackle this challenge, but recent evidence has indicated

245 To tackle this challenge, we develop a novel machine learni

246 bacterial pathogen Xanthomonas campestris To tackle this challenge, we first performed a transcriptom

247 sts and enzymes offer complementary means to tackle this challenge.

248 ular parameters provides invaluable tools to tackle this challenging issue.

249 ents a novel potential therapeutic target to tackle this devastating pathology.

250 We introduce a novel modeling framework to tackle this difficulty using impulsive differential equa

251 nd hopefully a series of new drug targets to tackle this disease.

252 cent expansion of electrochemical sensors to tackle this hurdle requires sensors that can undergo ana

253 To tackle this issue and complement experimental efforts fo

254 Here, we tackle this issue by combining voxel-encoding modeling a

255 Here we tackle this issue via computer simulations which reveal

256 We tackle this issue with a newly developed algorithm that

257 Herein, we tackle this issue with a unique combination of multiscal

258 To adequately tackle this issue, an effective detection method is requ

259 analysis, we investigate different means to tackle this issue.

260 To tackle this limitation, we propose a probabilistic appro

261 They tackle this problem by sequestering heme into bioinert c

262 Here we review studies that tackle this problem from a diverse set of approaches, fr

263 One promising approach to tackle this problem is chemical synthesis inside nanocap

264 rning model that is specifically designed to tackle this problem is still lacking.

265 To tackle this problem, the identification of principal res

266 To tackle this problem, we constructed a multimodal neural

267 To tackle this problem, we designed a skin cancer model for

268 To tackle this problem, we developed a method to obtain a f

269 To tackle this problem, we engineered an HA tag onto Cx26 o

270 To tackle this problem, we first design a sinogram filling

271 To tackle this problem, we utilized a 3D co-culture model i

272 However, dentistry has so far been unable to tackle this problem.

273 er per primitive cell, is an ideal system to tackle this puzzle.

274 Here, we tackle this question in human induced pluripotent stem c

275 To tackle this question, we compared the effect of the herp

276 Here we are proposing an approach to tackle this question.

277 arnesoid X receptor), as our model system to tackle this question.

278 In this issue, Yu et al (2019) tackle this venture by taking advantage of single-cell t

279 To tackle this, epidemics on networks are approximated by a

280 We tackled this problem by determining the H(2)O content of

281 In this study, we tackled this problem by systematically assessing RAD51 b

282 Recent studies have tackled this problem using multiple samples sequenced fr

283 We tackled this question in a context-dependent timing task

284 Yet, few studies tackled this question in situ at the outbreak level, due

285 Here, we tackled this question in the context of motion processin

286 e actions in human endeavors, few works have tackled this topic extensively and quantitatively.

287 Our review tackles this heterogeneity problem, providing considerat

288 Tackling this challenge, this study presents solid-state

289 ries of data and have shown great utility in tackling this flood of genomic data, while using minimal

290 Tackling this latter question can facilitate understandi

291 A key to tackling this pandemic is to understand the receptor rec

292 cuss models, experiments, and approaches for tackling this question, and for understanding how new pr

293 e development of machine learning methods to tackle three primary challenges in plant phenotyping: la

294 ution observed in the proton spectrum can be tackled through the corresponding (13)C NMR spectrum whe

295 tations and challenges that still need to be tackled to reach a complete and accurate picture of thei

296 ys remain challenging questions that must be tackled to understand the dynamical aspects of parietofr

297 investigated as a cost-effective strategy to tackle U contamination in the subsurface.

298 olicies, suggesting that inequalities can be tackled with appropriate social and economic interventio

299 This challenge can be tackled with the recourse of enabling technologies that

300 A One Health approach to tackle zoonotic cryptosporidiosis looking at new advance