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1 tion of tissue from the primitive streak and tailbud.
2 esicle, a transient structure of the teleost tailbud.
3 esembling the mammalian primitive streak and tailbud.
4 me-lapse cell tracking data of the zebrafish tailbud.
5 and ultimately promotes cell death in chick tailbud.
6 ith FGF signalling decline in the late chick tailbud.
7 l stem cells and mesoderm progenitors in the tailbud.
8 n the posteriormost embryonic structure, the tailbud.
9 and Wnt target genes in the mouse and chick tailbud.
10 required for somitic precursors to exit the tailbud.
11 n cell fate markers is apparent in the human tailbud.
12 cell migration and cell adhesion within the tailbud.
13 nical and non-canonical Wnt signaling in the tailbud.
14 perinotochordal expression in the posterior tailbud.
15 nteroposterior neuraxis, midline, and streak/tailbud.
16 posterior tailbud progenitors move into the tailbud.
17 vements and behavior in wild type and mutant tailbuds.
18 n of LS neural segments with and without the tailbud, after isolation of normally positioned LS segme
19 spt is mutated, embryos develop an enlarged tailbud and are only able to form roughly half of their
20 careful balance between cells that leave the tailbud and cells that are held back in order to give ri
21 sure the 3D cell flow field of the zebrafish tailbud and identify changes in tissue fluidity revealed
22 An early step during this process occurs at tailbud and involves dissolution of the basement membran
23 of development, Hoxb-13 is expressed in the tailbud and posterior domains in the spinal cord, digest
24 GF-dependent mesoderm identity in late stage tailbud and provide evidence that rising endogenous reti
25 cell population that is incorporated in the tailbud and required for axial elongation of the mouse e
26 ise in endogenous retinoid signalling in the tailbud and show that here FGF no longer opposes retinoi
28 nt3a and wnt8 are expressed in the zebrafish tailbud and that simultaneous inhibition of both wnt3a a
31 lly positioned LS segments from the stage 13 tailbud, and after axial displacement of posterior parax
32 vergence-extension of cells as they exit the tailbud, and finally by a late volumetric growth in the
35 cts are due to non-autonomous effects on the tailbud, and present evidence that the tailbud defects a
36 ortional levels of activity in the zebrafish tailbud, and this balance is important for axis elongati
39 mp inhibitors expressed just anterior to the tailbud are important to restrain Bmp signaling we produ
40 Data suggest that inductive signals from the tailbud are primarily responsible for the programming of
41 hat some cell movements and behaviors in the tailbud are similar to those seen during gastrulation, w
44 aises the possibility that FGF maintains key tailbud cell populations and that rising retinoid activi
46 opment include the bilateral distribution of tailbud cell progeny and the exhibition of different for
49 LS neural tube formation (stages 12-14), the tailbud contains the remnants of Hensen's node and the p
50 ons in the post-anal tail are generated from tailbud, declining Fgf signalling is less effective at i
51 n the tailbud, and present evidence that the tailbud defects are caused by alterations in Wnt signali
53 ow that BMP4, a paracrine factor secreted by tailbud-derived mesenchyme, is required for ureter morph
54 e derived from the intermediate mesoderm and tailbud-derived mesoderm, which is selectively associate
59 These double mutants also develop a large tailbud due to the accumulation of progenitor cells that
60 e left lateral plate mesoderm (L LPM) during tailbud/early somitogenesis stages is associated in all
62 in the midline, over a substantial period of tailbud embryogenesis, and therefore lend further insigh
63 cular marker of pronephric specification, in tailbud embryos indicated that injected xWT1 mRNA inhibi
64 overexpressing Xnr1 placed into the R LPM of tailbud embryos induced the expression of the normally L
68 n transgenic mouse embryos, is stimulated in tailbud fragments when cultured in presence of Gdf11, a
71 itogenesis to constrain Bmp signaling in the tailbud in order to allow normal expression of Wnt inhib
72 mitogenesis results in severe defects in the tailbud, including altered morphogenesis and gene expres
73 promote epibolic migration of cells into the tailbud, increasing tail formation at the expense of hea
74 oxd11/lacZ expression in cultured transgenic tailbuds, indicating that Smad3 may play a similar role
76 e that germ layer induction in the zebrafish tailbud is not a simple continuation of gastrulation eve
78 Specifically, we find that the zebrafish tailbud is viscoelastic (elastic below a few seconds and
90 major transcription factor for gastrulation, tailbud patterning, and notochord formation; however, ho
94 ior tailbud to promote cell migration during tailbud protrusion, and that defective migration of thes
96 erential posterior movement of cells in this tailbud region and to the general extension of the tail.
99 ylinositol-specific phospholipase C to early tailbud stage axolotl embryos reveals that a specific su
101 each ectoderm cell of the late neurula/early tailbud stage embryo, a time point just before onset of
102 ically blocks tail formation when induced in tailbud stage embryos, comfirming the importance of Xhox
103 pecific expression pattern of xmdc11a at the tailbud stage in the cranial neural crest and in a subse
105 d genetic inhibition of BMP signaling at the tailbud stage resulted in severe inhibition of endocardi
106 sufficiency of no tail expression as late as tailbud stage to drive medial precursor cells towards th
107 of the germ line did not occur until the mid-tailbud stage, days after the somatic germ layers are es
109 tion and axis formation, however, during the tailbud stage, MocuFH1 is also expressed in ventral cell
110 al crest cells from all axial levels, at the tailbud stage, Sox10 is downregulated in the cranial neu
111 reshadowed by different somite counts at the tailbud stage, thought to be a highly conserved (phyloty
116 progress faster through epiboly, leading to tailbud-stage embryos that have a narrow axis and an enl
118 tead the archenteron cavity almost closes at tailbud stages before providing a nucleus for the defini
119 ebrate chordate Ciona forms a tapered rod at tailbud stages consisting of only 40 cylindrical cells i
120 ay: inhibition with MEK or Fgfr inhibitor at tailbud stages in Ciona results in a larva which fails t
121 established as being between 60% epiboly and tailbud stages using the Fgf receptor inhibitor SU5402.
125 en restarts in a second phase at neurula and tailbud stages, firstly in two symmetric patches near th
135 as evidence for pluripotent cells within the tailbud, suggest that complex inductive mechanisms accom
136 dermal cells along the posterior wall of the tailbud that make a germ layer decision after gastrulati
137 these and adjacent regions indicate that, at tailbud, the oral ectoderm is not specifically required
138 activity initiates during cell exit from the tailbud, then runs down in the anterior-ward cell flow i
140 formed ATAC-seq experiments on isolated E9.5 tailbud tissue, which revealed minimal changes in chroma
141 ignaling is activated in the ventroposterior tailbud to promote cell migration during tailbud protrus
142 during gastrulation, continues to act in the tailbud to specify hypochord from a notochord/hypochord
143 scription and protein phosphorylation in the tailbud, to distinguish early effects of signal perturba
144 dorsal tissues, we find that the neurula-to-tailbud transition depends in part on activities of vent
149 n the zebrafish, a fate map of the zebrafish tailbud was generated along with a detailed analysis of
151 a population of multipotent precursors, the tailbud, which will give rise to all of the posterior st
152 ll fates and gene expression patterns in the tailbud will help to determine the nature of this import
154 tion of WNT3A and FGF8 in the CS15 embryonic tailbud, with a 'burst' of apoptosis that may remove neu
155 domains for Cdx expression (primitive streak/tailbud), yet, overall, they contain elevated levels of