ライフサイエンスコーパス: tailor-made

1 Herein, a tungsten complex bearing a tailor-made 2,2'-((t)Bu(2)As)(2)-substituted tolane liga

2 blueprint for the design of a broad range of tailor-made 2D COFs with extended pi-conjugated building

3 irected evolution can generate proteins with tailor-made activities.

4 e and comparative chemical proteomics with a tailor-made activity-based probe, in combination with tr

5 rofiling (ABPP), in which broad-spectrum and tailor-made activity-based probes are combined to report

6 nt pathogen recognition receptors provides a tailor-made adaptive immunity for an efficient defense a

7 Tailor-made additional vaccination campaigns would be va

8 In contrast, when the tailor-made additives were incorporated into an insolubl

9 This strategy provides a route to tailor-made aldol catalysts with different substrate spe

10 ty of carbonyl compounds can be converted to tailor-made alkenes with phosphorus ylides under mild co

11 e potential of enzyme engineering to produce tailor-made alpha-glucans.

12 ith fused quartz/water interfaces containing tailor-made amino acids that serve as model systems for

13 t of helicene chemistry, toward a library of tailor-made and highly functionalized helicene molecules

14 Previously, we showed that tailor-made antioxidant-loaded particles can yield both

15 ectivity in radiochemistry make it an almost tailor-made application of click chemistry.

16 ble kinetic and thermodynamic parameters for tailor-made applications across a broad range of fields.

17 and identifying the best-performing MOFs for tailor-made applications in future practice.

18 tunities to synthesize exotic materials with tailor-made applications.

19 Regardless of the predictive factor used, a tailor-made approach is recommended accounting for indiv

20 its ability to eradicate CSC may serve as a tailor-made approach to enhance chemotherapeutic benefit

21 ting broader implementation of highly active tailor-made arylborane Lewis acids and Lewis pairs.

22 ive approach for in vivo generation of novel tailor-made bacterial polysaccharides.

23 s to design cell factories for production of tailor-made bio-based materials suitable for high-value

24 resulting system could lead to the design of tailor-made biomaterials that incorporate varying functi

25 ic biology or biomimetic chemistry to obtain tailor-made biosensors having the desired requirements o

26 This success has spurred the development of tailor-made biosensors that enable the study of dynamic

27 ning these polymerization systems to provide tailor-made block copolymers from chemically distinct mo

28 ith physicochemical properties programmed by tailor-made bMSNs.

29 r engineering synthetic RNA condensates from tailor-made, branched RNA nanostructures that fold and a

30 ctrical properties of molecular junctions by tailor-made "building block" peptides.

31 relations will guide the synthesis of novel, tailor-made carbohydrate materials.

32 d to fundamental advances and development of tailor-made catalysts.

33 mation could facilitate subsequent design of tailor-made chaperones.

34 ompositions are needed to produce devices of tailor made characteristics.

35 Molecularly imprinted polymers (MIPs) are tailor-made chemical receptors that recognize and bind t

36 NA ligands, enzymes, and nanostructures with tailor-made chemistry.

37 application of stereoselective antibodies as tailor-made chiral selectors for the separation of enant

38 d, it was possible to create a ready-to-use, tailor-made chiral uniformly (13)C and (15)N labeled [U

39 In this study, tailored-made citrus pectin-derived compounds were produ

40 y and medicine, generation of proteases with tailor-made cleavage specificities remains a major chall

41 EAK employs a novel in-house algorithm and a tailor-made Clique Percolation Method to extract linear

42 We designed and synthesized a tailor-made COF structure with electroactive hexaazatrip

43 fic cytotoxicity, and provide strategies for tailor-made combination therapies.

44 e atomic level has the potential to generate tailor-made components with enhanced performance for a v

45 The results suggest that tailor-made containment measures could reduce transmissi

46 icity, which was trained on a comprehensive, tailor-made database of enzyme-substrate interactions at

47 oxolane and dioxane ions were generated from tailor-made dehydroxyl derivatives inspired by natural 1

48 ular construction system allows not only for tailor-made design but also for an immense variety of bu

49 nd microcapsules holds great promise for the tailor-made design of new functional materials.

50 Here we used a tailor-made design to study indirect transmission experi

51 This work highlights the potentiality of tailor-made designs en route to compounds with desirable

52 Tailor-made: Discussed herein is the ability to adapt bi

53 ions and experiments with virus particles in tailor-made disk- and annulus-shaped microchambers, that

54 The charge transport characteristics of 11 tailor-made dithiol-terminated oligo(phenylene-ethynylen

55 The laboratory evolution of enzymes with tailor-made DNA cleavage specificities would represent n

56 The tailor-made DOTA-conjugated PSMA inhibitor PSMA-617 pres

57 A tailor-made, dual-illumination light sheet system acquir

58 requires the development and exploitation of tailor-made, easy-to-use and flexible tools designed spe

59 A-based polymers open up a new avenue toward tailor-made efficient photocatalysts with broad photocat

60 The development of tailor-made electrochromic (EC) materials requires a lar

61 without the plethora of available NHCs with tailor-made electronic and steric properties.

62 Networks using quantum resources with tailor-made entanglement structures have been proposed f

63 This achievement demonstrates how efficient, tailor-made enzymes which control rate, pKa, substrate a

64 catalysis and a means of engineering novel, tailor-made enzymes.

65 ely pave the way for both enhanced yield and tailor-made EPS production by thermophilic bacteria.

66 ion is calibrated to the clonal data using a tailor-made expectation-maximization algorithm.

67 A tailor-made experimental design was used to screen the e

68 lassification system is used which provides, tailor-made, experts' feedback using an online decision

69 b-millisecond mixing and reaction regimes in tailor-made flow devices.

70 A tailor-made fluorescent indicator cross-linker was thus

71 Thereby, the pool of tailor-made fluorescent nucleic acid conjugates can be e

72 carbohelicenes and their derivatives can be tailor-made for a better involvement in several subfield

73 cation of biosensors that can potentially be tailor-made for a variety of applications.

74 nt care will improve because therapy will be tailor-made for both the disease and the patient.

75 to generate novel protein scaffolds that are tailor-made for catalysis.

76 sequent fabrication of OLEDs/LECs, which are tailor-made for each specific application.

77 ly, supported by a changing milk composition tailor-made for each stage of development.

78 two specific picolinate two-photon antennas (tailor-made for each targeted metal) and one acetate arm

79 emistries and scaffolds to produce libraries tailor-made for finding or optimizing a lead directed at

80 Radial mesoporous silica (RMS) sphere was tailor-made for further applications in producing shape-

81 nzymes are Nature's polyfunctional catalysts tailor-made for specific biochemical synthetic transform

82 schemes may include designer cells that are tailor-made for the desired chemical and production proc

83 gas-phase complex with Cl(-) was found to be tailor-made for the macrocycle 1, while 1 + SA(-) (SA(-)

84 the design of individualized routes that are tailor-made for the specific targets.

85 s revealed strategies to design new peptides tailor-made for the stabilization of specific proteins.

86 es, showing redesigned activities to produce tailor-made fructooligosaccharides.

87 moplastic microfluidic device comprises five tailor-made functional layers, and the chip is compatibl

88 DNA receptors (aptamers) and catalysts with tailor-made functional properties.

89 'function generator' method for programming tailor-made gene expression signals in live bacterial ce

90 Zinc finger nucleases (ZFNs) facilitate tailor-made genomic modifications in vivo through the cr

91 machineries, it is now possible to generate tailor-made glycoconjugates by attaching polysaccharides

92 -functionalization is revealed for producing tailor-made graphene and COP materials for efficient ene

93 A 'tailor-made' group B meningococcal vaccine was successfu

94 a key component of personalized medicine and tailored-made health care are greatly anticipated follow

95 We therefore developed a tailor-made hierarchically structured indium-tin oxide e

96 Here, we report a novel tailor-made HS mimetic, which furnishes an exclusive idu

97 cocatalyzed photoelectrode systems to design tailor-made hybrid devices for a wide range of catalytic

98 Here, we propose a tailor-made indicator to serve precisely this purpose fo

99 A tailor-made ink was studied, and the residual activity o

100 Crybodies as a powerful tool for developing tailor-made insecticides against new target insects.

101 synthesising frameworks to construct various tailor-made interfaces, and for exploring skeletons and

102 a the click reaction, endowing the MOFs with tailor-made interfaces.

103 electrochemical evidence clearly shows that tailor-made interfacial configurations of the ionic self

104 an essential role in subtilisin folding as a tailor-made intramolecular chaperone.

105 By combining tailor-made iridium complexes with naphthalenes, we demo

106 nd block chemistries to furnish a library of tailor-made Janus particles with widely tunable physical

107 suggest that drinking 600 mL per day of our tailor-made kombucha might be the feasible amount of kom

108 the long-term effectiveness of a randomized, tailor-made lifestyle intervention, consisting of diet a

109 a new strategy for constructing kinases with tailor-made ligand binding properties.

110 of bead surfaces for uptake of Pu within the tailor-made LOV platform that fosters processing of larg

111 r which advanced data-processing methods and tailor-made materials are required.

112 ich is a prerequisite for the development of tailor-made materials for advanced applications.

113 obic effects, which are all useful motifs in tailor-made materials.

114 re seedling growing in a transparent soil in tailor-made mesocosms, maintaining physical conditions f

115 Three new tailor-made molecules (DPDCTB, DPDCPB, and DTDCPB) were

116 g to an improvement in the de novo design of tailor-made molecules for future applications.

117 his study demonstrates the ability of simple tailor-made monochemical surfaces to influence binding r

118 polymer-based membrane via the synthesis of tailor-made monomers as an important step toward selecti

119 ight how different microrobots, ranging from tailor-made motile bacteria and tiny bubble-propelled mi

120 Here, we combine a tailor-made mouse iPSC reprogramming system and high-res

121 ternative to both manual term collection and tailor-made named entity recognition methods.

122 vide new insights into design principles for tailor-made nanomedicine platforms.

123 ities in complex biological samples by using tailor-made nanoparticles.

124 within the inner hydrophobic cores of these tailor-made nanoreactors, and products made therein are

125 science and chemistry, and the emulation of tailor-made nanoscale superstructures realized in the na

126 Considering this, we delved into tailor-made natural deep eutectic solvents coupled with

127 H-modified GNs (GNs-PAH) in conjunction with tailor-made negatively charged CdS quantum dots (QDs) we

128 of access to their azolium salt precursors, tailor-made NHCs are readily available.

129 accuracy, high resolution data combined with tailor-made nontarget processing methods (all available

130 er types of tinnitus sound treatment such as tailor-made notch music training and limitations of our

131 and optimal treatment of prostate cancer, a tailor-made novel naphthyl-containing DOTA-conjugated PS

132 s are propagated through time efficiently by tailor-made numerical methods.

133 ethod to extract the figure of merit zT of a tailor-made oligo(phenyleneethynylene)-9,10-anthracenyl

134 of nano- and micrometer-sized particles with tailor-made optical properties for biological, diagnosti

135 te a toolkit of methods that allow preparing tailor-made organic cages for a number of distinct appli

136 Novel routes are being explored to create tailor-made organic materials, and recent progress in or

137 lexity can be systematically addressed using tailor-made organic surfaces and interfaces.

138 C bond cleavage was developed by employing a tailor-made organotitanium half-cage complex.

139 Improvements in the synthesis of tailor-made PEIs in combination with new in-depth analyt

140 osites by self-assembly of polypeptides with tailor-made peptide sequences.

141 hat have the potential for new and effective tailor-made pharmacotherapy for patients with Cushing's

142 is a requirement for the efficient design of tailor-made photochemistry.

143 ed, and the dications are utilized as novel, tailor-made photoredox catalysts in the direct oxidative

144 opened new avenues and new perspectives for tailor-made plates, not only with regard to layer materi

145 g starch biosynthesis in crops to synthesize tailor-made polyglucans.

146 of the oxidative cyclodehydrogenation of the tailor-made polymer precursor into 8-AGNRs was validated

147 hniques have been extensively used to design tailor-made polymer prodrug nanocarriers.

148 his approach now allows for the synthesis of tailor-made polymers that decrease the induction time fo

149 yclodehydrogenation, or "graphitization," of tailor-made polyphenylene precursors.

150 d their distances, researchers can construct tailor-made probes for interrogating multivalent interac

151 Our long-term vision is to design tailor-made production of any moth pheromone component i

152 Hence, GAs can produce cements with tailor-made properties and differentiation potential for

153 o the specific design of hybrid systems with tailor-made properties are evaluated, followed by a disc

154 ring new cutinase-inspired biocatalysts with tailor-made properties.

155 pment of tunable RE-based flexible MOFs with tailor-made properties.

156 variety of proteases and the construction of tailor-made protease editors for site-selectively and ir

157 (cap) to overcome key challenges en route to tailor-made proteases suggests easier access to such rea

158 Protein engineering enables the creation of tailor-made proteins for a variety of applications.

159 The use of a tailor-made quinoline ligand is also crucial for this re

160 Molecularly imprinted polymers (MIPs) are tailor made recognition materials that can mimic biologi

161 w for design of redox-active proteins having tailor-made redox potentials for applications such as ar

162 rug delivery mechanisms as well as designing tailor-made release profiles.

163 ctrode pretreatment and the integration of a tailor-made script for data treatment.

164 Tailor-made selective artificial recognition sites are t

165 ia a thermodynamic template approach using a tailor-made selective cation, effectively maintain their

166 s a versatile tool, promising for developing tailor-made semiconductor materials.

167 ns the way to generate many new enzymes with tailor-made sequence specificities desirable for various

168 This tailor-made serpin was shown to form covalent complexes

169 Tailor-made siRNA library screening was performed for al

170 to stimulate further research in the area of tailor-made soft silicone elastomers for novel applicati

171 Development of tailor-made software (e.g., smartphone applications) for

172 oduce the PrISMa (Process-Informed design of tailor-made Sorbent Materials) platform, which integrate

173 phase extraction (SPE) cartridge to serve as tailor-made sorbents for the separation of thiabendazole

174 vanced building blocks for rapid assembly of tailor-made spacers and rulers.

175 wide selection of fluorescent pH-probes with tailor-made spectral properties, sensitive ranges, and i

176 ent could be an efficient method to produce 'tailor-made' starch, that can be further utilized in foo

177 n of dry and solvent fractionation to obtain tailor-made stearins is discussed.

178 heir synthetic utility for the production of tailor-made, sterically constrained alpha-amino acids, w

179 ngs of the mRNA and tRNA paths, suggesting a tailor-made structural organization of the mito-SSU for

180 ng class of crystalline porous polymers with tailor-made structures and functionalities.

181 Insights into tailor-made structures, material design strategies, and

182 carbon nanotubes (CNTs), and graphenes] with tailor-made supramolecular (small molecular) or polymeri

183 of immobilized species may ultimately allow tailor-made surfaces to be generated.

184 clinical course of the disease and to allow tailor-made surveillance of individuals at risk, but als

185 which might provide insights that allow the tailor-made synthesis of CB[n] homologues and derivative

186 that circumvents the challenges posed by the tailor-made synthesis of macrocyclic CB[n] by preparing

187 The tailor-made synthesis of these CB[n] analogues proceeds

188 Molecularly imprinted polymers (MIPs) are tailor-made synthetic antibodies possessing specific bin

189 e receptor mutant that would be activated by tailor-made synthetic ligands, we mutated the human A(3)

190 erivatives, and analogues by straightforward tailor-made synthetic procedures.

191 By employing a tailor-made synthetic strategy, a library of highly sulf

192 ine kinase inhibitors seem well suited to be tailor-made therapeutics for EGFR mutant NSCLC; however,

193 each geographic region that include antigens tailor-made to match local circulating HIV-1 strains.

194 s of bisintercalating redox probes have been tailor-made to meet specific requirements of electrochem

195 versatile biosensors have proven themselves tailor-made to the study of signal transduction, and in

196 functional domains also allows the design of tailor-made transcription factors for specific genes.

197 techniques should permit application of this tailor-made treatment to large numbers of non-Hodgkin's

198 es and can aid better clinical diagnosis and tailor-made treatment.

199 Tailor-made water-soluble macromolecules, including a gl

200 ndent on the availability of broadly diverse tailor-made, well-defined, and often complex oligosaccha

201 e loading of 10 g L(-1) in the presence of a tailor-made whole-cell catalyst.

202 t for students wishing to organise their own tailor-made workshops.

203 gnition is sufficiently well understood that tailor-made ZF-based DNA-binding proteins can be enginee

204 ormation of tetrapyrrolic Zn-N(4) sites in a tailor-made Zn-N-C material is utilized as an active-sit