ライフサイエンスコーパス: tapering

1 tal reductions in antibiotic quantity (dose 'tapering').

2 ral prednisone (0.75 mg/kg/day, with gradual tapering).

3 seizures, and did not result from medication tapering.

4 drawal may be minimized by earlier or slower tapering.

5 of participants experienced a relapse after tapering.

6 onducted to compare 2 regimens of prednisone tapering.

7 ihypertensive medication, and fast corticoid tapering.

8 flammatory biomarkers in serum after steroid tapering.

9 eduction group had zero exacerbations during tapering.

10 nces, suggesting its utility for safe opioid tapering.

11 our data and, furthermore, predicts plus-end tapering.

12 e is limited evidence to guide buprenorphine tapering.

13 ified predicting the feasibility of extended tapering.

14 g the tip-focused cell files that facilitate tapering.

15 many patients had prior negative experiences tapering.

16 oid therapy are increasingly undergoing dose tapering.

17 locking technique based on the longitudinal tapering.

18 polymyalgia rheumatica during glucocorticoid tapering.

19 ited to synthesize nanorods with a minimized tapering.

20 rate of uveitis recurrence after adalimumab tapering.

21 tly during anti-TNF or concomitant treatment tapering.

22 esponsive to corticosteroids, but recur upon tapering.

23 tern" transition formed at the distal end by tapering.

24 8), and the group taking 0.01% atropine then tapering 0.01% atropine had more axial elongation (adjus

25 ely, in the group taking 0.01% atropine then tapering 0.01% atropine, and no reports in both placebo

26 = 29 and n = 25 [86.2%]; 0.01% atropine then tapering 0.01% atropine: n = 73 and n = 67 [91.8%], resp

27 andomly assigned in a 2:1 ratio to receive a tapering 15-day course of oral prednisone (5 days each o

28 (awNO), and/or C(ANO), and post 8- to 10-day tapering 40 mg prednisone (recovery).

29 Among the patients who underwent dose tapering, 54.3% were women (vs 53.2% among those who did

30 of disease, the period of inactivity before tapering adalimumab, and the tapering schedule were coll

31 rt consensus statements relating to OCS use, tapering, adverse effects, adrenal insufficiency, and pa

32 sensus statements were generated on OCS use, tapering, adverse-effect screening, and shared decision-

33 jectives: To develop expert consensus on OCS tapering among international experts.Methods: A modified

34 se of benzodiazepine receptor agonist during tapering and augments CBTI with novel cognitive and beha

35 nts have successfully allowed for more rapid tapering and discontinuation of corticosteroids in OLTx

36 increase in platelet count persisted despite tapering and discontinuation of immunosuppressive therap

37 ngly support a strategy based on progressive tapering and discontinuation of TPO-RAs for patients wit

38 It also allows tapering and discontinuing corticosteroids in most patie

39 Tapering and eventual withdrawal of insulin should be at

40 ppressive agents often allows corticosteroid tapering and improves the efficacy of therapy.

41 to precisely control sequences and suppress tapering and misincorporation errors, thus achieving wel

42 precisely control BCP sequences and suppress tapering and misincorporation errors.

43 l, of which the keystones are gradual dosage tapering and psychological support when necessary.

44 econdary endpoints, including glucocorticoid tapering and time to first severe flare, were met.

45 pared with placebo, including glucocorticoid tapering and time to first severe flare.

46 We report here that TH cell somata, tapering and varicose inner plexiform layer neurites, an

47 of outcomes as a function of tapering (vs no tapering) and dose reduction velocity.

48 f clinical access to monitor patients during tapering, and concerns about patient resistance.

49 options for recurrent CDI, but a prolonged, tapering, and pulse-dosed regimen of oral vancomycin is

50 s lacking on which patients may benefit from tapering antidepressant medication while receiving a psy

51 ed use of a psychological intervention while tapering antidepressant medication with antidepressant m

52 ary outcome was higher in the rapid- vs slow-tapering arm (23 [39%] vs 5 [9%]), with a risk ratio of

53 A total of 117 patients (58 in the slow-tapering arm and 59 in the rapid-tapering arm) were sele

54 The rapid-tapering arm consisted of immediate high-dose daily admi

55 The slow-tapering arm included a gradual increase of the predniso

56 in the slow-tapering arm and 59 in the rapid-tapering arm) were selected for inclusion by MG speciali

57 p30 had a striking ovoid morphology with no tapering at the tip structure, making the attachment org

58 Dendritic tapering away from the soma has been suggested to both e

59 with a net rotation of the broad end of its tapering body.

60 oint of weaning successfully off TLAs before tapering brexanolone.

61 Current guidelines suggest gradual tapering, but what the optimal speed of this tapering sh

62 c or continues to recur with each attempt at tapering corticosteroid.

63 Tapering could also alter use of health care services an

64 For instance, opioid tapering could help patients reduce opioid exposure to p

65 nicotine patch alone for a standard 10-week, tapering course (n = 64) or the combination of nicotine

66 subdural hematoma in a 1:1 ratio to a 19-day tapering course of dexamethasone or to burr-hole drainag

67 e randomly assigned to receive a 6-to-8-week tapering course of either dexamethasone or placebo in ad

68 Participants were randomized to a 10-day tapering course of hydrocortisone or placebo beginning a

69 assigned in a 1:1 ratio to receive a 2-week tapering course of oral dexamethasone, starting at 8 mg

70 ys of pulse methylprednisolone followed by a tapering course of oral prednisone therapy.

71 consideration should be given to a prolonged tapering course when these medications are used for this

72 Opioid tapering, defined as 15% or more relative reduction in m

73 Opioid tapering, defined as at least 15% relative reduction in

74 tonomous feature of principal neurons, where tapering dendrites show an inverse distribution of spine

75 ermines filopodia initiation frequency along tapering dendrites.

76 lie differences in firing pattern, while the tapering diameter of AIS may define a trigger zone for a

77 Dupilumab tapering did not compromise outcomes; treatment continua

78 ld be used to model interventions for proper tapering, discontinuation, or follow-up of new start mid

79 l improvement was assessed by monitoring the tapering/discontinuation of prednisone and DMARDs, and b

80 ive in the proximal portion of the trunk and tapering distally, with this rind of bark providing most

81 chotic dose between the start and the end of tapering, divided by the number of days in between.

82 Treatment with 80 mg per day prednisone with tapering dose and adalimumab, induction and maintenance,

83 ed daily i.p. injections of a human-relevant tapering dose of dexamethasone (D; n = 8; 0.5, 0.3, 0.1

84 s, patients were randomized to receive a 9-d tapering dose of either oral prednisone or placebo.

85 She was managed with a tapering dose of systemic corticosteroids.

86 Prednisone (30 mg/d) was given in a tapering dose schedule during the first three cycles.

87 suppression in the form of cyclosporine at a tapering dose that allows for long-term allograft surviv

88 ves the use of systemic corticosteroids with tapering doses extending up to 9 months after the initia

89 enal transplant recipients were treated with tapering doses of prednisone (Pred) and with a concentra

90 ation-controlled regimen of cyclosporine and tapering doses of prednisone.

91 et levels of 5 to 15 ng/mL and prednisone in tapering doses.

92 ne equivalents over 75 days, with an average tapering duration of 124 days (range: 6-334 days).

93 e the growth mechanism and to understand the tapering during the shape evolution processes.

94 for a sharp switch in mechanism without the tapering effect.

95 rent fabrication technologies are limited by tapering effects and the need for direct line of sight t

96 The study included 21 515 tapering events among 19 377 patients with a mean (SD) o

97 able, long-term, higher-dose opioid therapy, tapering events were significantly associated with incre

98 proximal and medial regions in branching and tapering exponents, these effects were compensatory, res

99 ding to steroids were treated for 18 mo in a tapering fashion.

100 al obesity, gynecomastia, hypogonadism, long tapering fingers and large ears.

101 ermined by clinical improvement, followed by tapering for a total of 8 or 14 days) or to receive plac

102 ins), with different treatment durations and tapering for immune thrombocytopenia and autoimmune haem

103 t unintended negative consequences of opioid tapering for policy makers and clinicians to consider.

104 ise from their neurite geometries (diameters tapering from 10-20 um to < 2 um at their terminal tips)

105 nts were US adults who underwent opioid dose tapering from 2008 to 2017 after a 12-month baseline per

106 The central channel is funnel shaped, tapering from an inner diameter of about 30 angstroms at

107 of the weaning rate for each patient during tapering from opioid and benzodiazepine medications was

108 the concept that the resting ion channel is tapering from the extracellular mouth to the middle port

109 fer significantly between the slow- vs rapid-tapering group (13 [22%] vs 21 [36%], P = .15).

110 Opioid tapering has been associated with negative consequences,

111 Opioid dosage tapering has emerged as a strategy to reduce harms assoc

112 treated with aspirin, ticlopidine and a 60-h tapering heparin regimen.

113 Upon tapering her prednisone, however, she became dyspneic an

114 phere comprised of ~700 ommatidia, packed as tapering hexagonal prisms between a rigid external array

115 Tapering immunosuppression led to the recuperation of in

116 Treatment given in these cases consisted of tapering immunosuppression, antiviral therapy, unprocess

117 es that may explain high relapse rates after tapering immunosuppression.

118 nisone (60 mg/m(2) per day) for 3 weeks plus tapering in induction.

119 lines do not provide recommendations for OCS tapering in patients with asthma.Objectives: To develop

120 s limited information about risks related to tapering, including overdose and mental health crisis.

121 iologic hydrocortisone doses with subsequent tapering increases survival rate and shock reversal in p

122 ngs raise questions about potential harms of tapering, interpretation is limited by the observational

123 Recent studies suggest that tapering is associated with short-term risks of substanc

124 t psychotic episode, extra monitoring during tapering is required.

125 dius of curvature (250 microm), the shortest tapering length between the separation and turn widths (

126 exceeded the upper limits of normal arterial tapering (lesion/reference EEM CSA ratio < or = 0.78 or

127 ychological intervention during and/or after tapering may be an effective relapse prevention strategy

128 variate analysis, predictors of success were tapering morphology (odds ratio, 15.5; 95% confidence in

129 ytes transduced in vivo acquire the cardinal tapering morphology and physiological automaticity of na

130 PSD-95, and PSD-93), that TH cell somata and tapering neurites are also immunopositive for a gamma-am

131 ion to placebo nightly, tapering placebo, or tapering of 0.01% atropine eye drops for 1 year.

132 es, serological anticholinergic activity, or tapering of anticholinergic medications.

133 psychological intervention while undergoing tapering of antidepressant medication might be an altern

134 nts successfully reach and maintain extended tapering of at least 1x/12 weeks (Q12W), (2) evaluate di

135 ycin, started on Day -2, was maintained with tapering of blood levels until full withdrawal at 6 mont

136 Regimens allowing the tapering of corticosteroids have also helped reduce the

137 ff therapy in 90% of patients, despite rapid tapering of corticosteroids, thus allowing for a major c

138 mpt to control active synovitis and to allow tapering of corticosteroids.

139 ol specified adjunctive care and the use and tapering of corticosteroids.

140 national prescribing guidelines have led to tapering of doses among patients prescribed long-term op

141 a high initial dose followed by an extended tapering of doses is found to optimise the use of antibi

142 Tapering of dupilumab to once every 12 weeks (Q12W) can

143 polymyalgia rheumatica have a relapse during tapering of glucocorticoid therapy.

144 r an opportunity for intensive surveillance, tapering of immunosuppression, and preemptive therapy fo

145 riments revealed that increasing the outward tapering of microchannel sidewalls improved fluidic seal

146 ed for clear guidance and algorithms for the tapering of OCS together with the requirement for multid

147 GCA with IV GC pulses allowed for more rapid tapering of oral GCs and had long-term benefits, with a

148 weeks, combined with predefined standardized tapering of oral prednisone.

149 via tofacitinib enabled disease control and tapering of other immunosuppressive agents.

150 ctory to plasma exchange or resistant to the tapering of plasma exchange therapy.

151 Gradual tapering of prednisone and tacrolimus is proposed for pa

152 prednisone with azathioprine therapy, rapid tapering of prednisone appears to be feasible, well tole

153 ved a mandatory prednisone burst followed by tapering of prednisone over the course of 15 weeks.

154 The tapering of prednisone therapy in generalized myasthenia

155 relapses of gastrointestinal GVHD following tapering of prednisone; survival is statistically signif

156 flow law also predicts the observed forearc tapering of slip rate deficit with depth.

157 This method could have relevance for tapering of SSRIs.

158 dary Sjogren syndrome developed fever during tapering of steroids.

159 Here we show that the tapering of the basin outline and the more gradual topog

160 UB seem to govern vectorial arborization and tapering of the collecting system and its terminal diffe

161 marked reductions in serum BLyS levels, and tapering of the corticosteroid dosage often resulted in

162 weight per day for three days, followed by a tapering of the dose over a period of seven days.

163 mobilization of the pouch with resection and tapering of the lower end (AP reconstruction) and ileoan

164 of methadone for detoxification followed by tapering of the medication without continuation on disch

165 We experimentally demonstrate that tapering of the nanowire, which serves as the STO active

166 esult of impeded antibiotic influx caused by tapering of the tunnel passage rather than by correcting

167 Principles considering biosimilars and tapering of therapy were added, and the research agenda

168 (93.8%) of cases in a mean of 6.1 months via tapering of topical steroids in 15 (46.9%) of patients.

169 of patients with GCA and PMR, including the tapering of treatment.

170 Bursts, which are serial taperings of respiratory depth typically spanning minute

171 occurred after the withdrawal, or during the tapering, of immunosuppressive therapy.

172 totic cell death peaked at 2 days, gradually tapering off afterward, although scattered apoptotic cel

173 Finally, tapering off anticholinergic medication improved the sco

174 From a clinical perspective, tapering off anticholinergic medication in patients with

175 emporal trends analysis showed ascent curves tapering off at approximately weeks 4 to 6.

176 dose of 60 mg/day of prednisone for a week, tapering off by 6 months.

177 After tapering off corticosteroids, he received the fourth dos

178 dramatic therapeutic response and enabled a tapering off of corticosteroids.ConclusionDysregulated P

179 Despite tapering off oral steroids, PUK developed in the fellow

180 ial periods of minimal decay and decay rates tapering off over time were often observed, and a two-pa

181 tients but there are less studies related to tapering off the drugs.

182 ast one fifth of the patients despite slowly tapering off the glucocorticoids.

183 eached a maximum 6 hours after injury before tapering off to baseline levels by 3 days.

184 in adhering to guideline-concordant gradual tapering, offering mental health support, and ensuring p

185 Four patients were cured with IS treatment tapering only.

186 isorder from methadone to buprenorphine, and tapering opioids in patients with chronic, non-cancer pa

187 ICE 9: When de-prescribing PPIs, either dose tapering or abrupt discontinuation can be considered.

188 -0.11 mm (SD) (range, 0.3 to 1.4 mm) without tapering or central narrowing.

189 Fine-Gray models as a function of rapid dose tapering or discontinuation (vs gradual reduction or dis

190 t be used as a reason to support involuntary tapering or discontinuation of long term prescription op

191 iving dobutamine and one receiving dopamine, tapering or discontinuation of the inotropic infusion re

192 of the initiation of rituximab therapy, and tapering or discontinuation of their treatment with pred

193 incident OUD among patients exposed to rapid tapering or discontinuation was greater 25 to 48 months

194 ontaneous coronary artery dissection, distal tapering or long, smooth narrowing that may represent di

195 n ankylosing spondylitis, strategy trials on tapering or stopping TNF inhibitors in patients in remis

196 vary between centres, but frequently include tapering or substitution of opioids and concomitant co-a

197 Early and/or unnecessary tapering or treatment discontinuation for drug-related a

198 ticosteroids intravenously for 1 week then a tapering oral dose over 8 weeks.

199 All received a course of tapering oral prednisolone (1 mg/kg prior to taper).

200 robust clinical and spirometric response to tapering oral prednisone.

201 idence interval, 3.18-5.53], with the effect tapering over time.

202 0.0001); AP was correlated to aorto-femoral tapering (p < 0.0001) but not PWV.

203 ot significantly change over time during the tapering period in any of the groups.

204 eceded by a titration period, and ended by a tapering period.

205 nance in UC patients who were in the steroid-tapering phase of therapy.

206 Of the 110 patients who completed the tapering phase, the mean reduction from baseline was 42.

207 ars then rerandomization to placebo nightly, tapering placebo, or tapering of 0.01% atropine eye drop

208 31 and n = 29 [93.5%]; 0.01% atropine, then tapering placebo: n = 29 and n = 25 [86.2%]; 0.01% atrop

209 rior to either 26-week or 52-week prednisone tapering plus placebo with regard to sustained glucocort

210 uccessful treatment, without recurrence with tapering prednisone and adalimumab.

211 , and ensuring patient safety throughout the tapering process.

212 was considered an important goal during the tapering process.Conclusions: In this Delphi study, expe

213 g a very dense intraganglionic neuropil; (4) tapering processes (presumed dendrites) extended beyond

214 Dendrites are short stout tapering processes that are rich in ribosomes and Golgi

215 oid withdrawal symptoms during a residential tapering program.

216 se dose reductions are done with exponential tapering programmes that reach very small doses.

217 solone (2 mg/kg/d for 2 weeks) followed by a tapering protocol for 9 weeks (n = 70) or placebo (n = 7

218 op their MAT dose warrants the creation of a tapering protocol to guide clinicians.

219 escribed by an initial fast hydrolysis rate, tapering rapidly off, leading to a process that takes da

220 and turn widths (55 microm), and the largest tapering ratio (4:1 separation channel width to turn cha

221 provided individualized pain care and opioid tapering recommendations to patients.

222 The rapid-tapering regimen allowed sparing of a mean of 1898 mg (9

223 hout dexamethasone 0.1% eye ointment, with a tapering regimen based on the response to treatment.

224 lack explicit recommendations regarding the tapering regimen of glucocorticoids during induction the

225 r approximately 4 months, after which a slow tapering regimen was initiated.

226 those of therapeutic minimums, in line with tapering regimens for other medications associated with

227 0 mg/day for GCA, followed by individualized tapering regimens in both diseases.

228 e expected degree of internal elastic lamina tapering, remodeling was classified as positive (includi

229 tenance OCS therapy, with personalization of tapering rhythm and speed.

230 The slender tapering rostrum with retracted narial openings, large e

231 n 40 mg/day prednisone and followed the same tapering schedule as long as disease activity was contro

232 ssages from their primary care practice on a tapering schedule during the 30 days after discharge.

233 ssages from their primary care practice on a tapering schedule for 30 days following discharge.

234 oral glucocorticoid administered on the same tapering schedule in the two groups.

235 A slow tapering schedule is advisable.

236 s, and maintained for 2 weeks, followed by a tapering schedule of 10 mg every 2 weeks over a period o

237 activity before tapering adalimumab, and the tapering schedule were collected.

238 sone, 60 mg/day, followed by a predetermined tapering schedule.

239 of 30 mg twice daily or oral prednisone on a tapering schedule.

240 fectiveness, duration of required treatment, tapering schedules, and when to begin and stop treatment

241 confinement and flow, including spatial mode tapering, sequential non-Hermiticity on-off switching, d

242 Experts agreed that OCS tapering should be attempted in all patients with asthma

243 tapering, but what the optimal speed of this tapering should be, especially in patients who remitted

244 1 mg/kg/day, was started on a regular basis, tapering slowly.

245 %) had the "comet sign" (adjacent eccentric, tapering soft-tissue mass corresponding to the noncalcif

246 Tapering speed (in olanzapine equivalents mg/day) was ca

247 Logistic regression analysis showed that the tapering speed did not predict the risk of relapse (z=0.

248 The average tapering speed was 10 mg olanzapine equivalents over 75

249 lar infliximab, in patients who relapse upon tapering steroids and/or adding nonbiologic immunosuppre

250 tinib, tacrolimus, mycophenolate mofetil and tapering steroids, with adjustments made during the post

251 ic activity studies (382 patients), and nine tapering studies (186 patients).

252 nterior uveitis, suggesting that attempts at tapering suppressive medications is warranted after long

253 eitis), suggesting that periodic attempts at tapering suppressive medications is warranted.

254 the geometry of the cochlear duct manifests tapering symmetry, a felicitous design principle that ma

255 liver solutes arriving with sharp fronts and tapering tails, whereas thick channels (aspect ratio ~ 1

256 Tapering the dose reduced the incidence of AWS compared

257 of sedative/analgesic agents include slowly tapering the intravenous administration of these agents

258 inuing venlafaxine treatment should consider tapering the medication dose gradually.

259 at least one kinesin motor protein, NCD, in tapering the microtubules into a bipolar spindle.

260 ability in the MZM was achieved by carefully tapering the underlying Si waveguide to reduce the impac

261 s 53.2% among those who did not undergo dose tapering), the mean age was 57.7 years (vs 58.3 years),

262 ow-disease activity in some cases even after tapering therapy.

263 A width of 100 mum, tapering to a 1 mum point, and a 40 mum thickness help m

264 beginning at approximately 1 micrometer and tapering to approximately 0.5 micrometer in diameter.

265 M. pneumoniae cells are generally elongated, tapering to form the attachment organelle at one end of

266 nts have discontinued hormone therapy or are tapering to lower doses.

267 event on 22 January 2006, followed by rapid tapering to markedly decreased levels of seismicity.

268 eneity was detected in lesions, with gradual tapering toward perilesional NAWM.

269 the gray and subcortical white matter often tapering toward the ventricle.

270 slowly diverging, westward propagating rift, tapering towards the East Pacific Rise.

271 ti-inflammatory agent; follow through with a tapering treatment regimen.

272 treatment, but the optimal initial dose and tapering treatment regimens are unknown.

273 hough many samples had a gradually reducing (tapering) trend toward the high range.

274 een Leu(A16) and the spandrels of San Marco, tapering triangular spaces at the intersection of the do

275 ing superhelical coiled-coil to the wide and tapering tropomyosin densities seen in surface views of

276 f hydrocortisone for 5 days followed by dose tapering until day 11 (n = 190) or to receive placebo (n

277 n interval of 1x/2 weeks (Q2W) with possible tapering upon disease control.

278 Preoperative counseling for tapering use may prevent increased rates of adverse effe

279 e therapy during and/or after antidepressant tapering vs antidepressant monotherapy were available.

280 ratios (aIRRs) of outcomes as a function of tapering (vs no tapering) and dose reduction velocity.

281 tituted with CBMPs and mycophenolate mofetil tapering was allowed.

282 Immunosuppression tapering was associated with a lower PTLD mortality (16%

283 , a more extended period of remission before tapering was associated with a lower rate of recurrence

284 Tapering was associated with an adjusted incidence rate

285 Tapering was associated with fewer primary care visits i

286 These findings suggest that opioid tapering was associated with increased rates of overdose

287 In the overall cohort, tapering was associated with more emergency department v

288 rt study of patients prescribed LTOT, opioid tapering was associated with more emergency department v

289 For the hypertension or diabetes subcohorts, tapering was associated with reduced medication adherenc

290 Adalimumab tapering was commenced after a mean of 100.8 +/- 69.7 we

291 Glucocorticoid tapering was encouraged but not required per protocol.

292 tion replaced ATDC therapy and mycophenolate tapering was not allowed.

293 Dose tapering was possible in the majority of patients, with

294 n the rates of relapse during glucocorticoid tapering was studied in patients with giant-cell arterit

295 ch the channel is tapered, and the degree of tapering were explored.

296 had a response and underwent glucocorticoid tapering were randomly assigned to continued treatment w

297 ty and tip breakage associated with external tapering were successfully overcome with the internal ta

298 The size of Bi(0) equilibrates the tapering, whereby the length of the rods is gradually re

299 Opioid tapering, with 15% or more relative reduction in mean da

300 All patients underwent prednisone tapering, with patients in VISUAL-1 receiving an initial