ライフサイエンスコーパス: tautomer

1 ent way to measure the concentration of each tautomer.

2 followed by the 4-hydroxycoumarin open-chain tautomer.

3 e N-protonated, rather than the O-protonated tautomer.

4 exoamino group gave its 1H-pyrrol-3-aminium tautomer.

5 valuable method to identify the predominant tautomer.

6 cence spectrum of the active PLP ketoenamine tautomer.

7 a fast equilibrium lying far toward the keto tautomer.

8 e configuration and the neutral hydroxyimine tautomer.

9 xhibit a significant amount of the enolimine tautomer.

10 phenolic hydroxyl group in the hydroxyimine tautomer.

11 ich is negatively charged in the ketoenamine tautomer.

12 ct is an unanticipated dearomatized thiazole tautomer.

13 ter acylation, doripenem adopts the Delta(1) tautomer.

14 e reactive imine over the unreactive enamine tautomer.

15 xcited state of the N1H, 6-keto, N7H guanine tautomer.

16 se, was identified as an adenylated thiazole tautomer.

17 talyst via the unusual 1',4'-iminopyrimidine tautomer.

18 able than the corresponding dimers of the 1H tautomer.

19 ds spontaneously adopt the non-aromatic 4(H) tautomer.

20 antly shifts the equilibrium toward the enol tautomer.

21 stidine exclusively forms the less common pi-tautomer.

22 l bound ferrous porphyrin, i.e., its valence tautomer.

23 rbene quinoline-2-ylidene is not formed as a tautomer.

24 temperatures with no traces of the hydrazone tautomer.

25 r, consistent with its role as the catalytic tautomer.

26 t evolve spontaneously to a stable methylene tautomer.

27 of approximately 54 ps for both TA* and TB* tautomers.

28 cumulation of damaging radicals or mutagenic tautomers.

29 to distinguish among rapidly interconverting tautomers.

30 e conformations of the two neutral histidine tautomers.

31 idant activity for the both of CurE and CurK tautomers.

32 olution as equilibrium mixtures of N1 and N2 tautomers.

33 onfirmed the dynamic stability of these rare tautomers.

34 tion, by polarizing substrates to mimic rare tautomers.

35 olutions exists in the form of 7-1H and 7-2H tautomers.

36 etic acid exist as a pair of interconverting tautomers.

37 resent as a rapidly equilibrating mixture of tautomers.

38 t of disilene adducts to their silylsilylene tautomers.

39 g on the antiaromaticity of the photoinduced tautomers.

40 were identified as the H1 and H3 keto-amino tautomers.

41 rmation of a higher-energy protonated phenyl tautomer (2H(+)) prior to C-C bond breaking would produc

42 lting in normal (340 nm) and proton-transfer tautomer (480 nm) emissions with an overall quantum yiel

43 n the relative stabilities of carbaporphyrin tautomers, a series of aromatic and nonaromatic structur

44 (+)), with its higher energy ring-protonated tautomer allowing the requisite C-C bond cleavage.

45 isted as a broad ensemble of interconverting tautomers, among which enolic forms dominated.

46 hat it switches from the (tau)- to the (pai)-tautomer and changes its ring orientation in the M state

47 , the H37 structure is shifted toward the pi tautomer and less cationic tetrads, consistent with fast

48 eaction occurs via N-acylation of the lactim tautomer and that cation-pi interactions play a key role

49 data shows a strong correlation between the tautomer and the H-bond accepting ability of the solvent

50 itated the identification of the most stable tautomers and conformers for both neutral and anionic AA

51 (hydrogenation) states, displaying different tautomers and conformers.

52 We identified several KP1212 tautomers and found that >60% of neutral KP1212 is prese

53 rbation of an equilibrium between asymmetric tautomers and inconsistent with isotope-induced desymmet

54 Inclusion of all tautomers and ionization ligand species was essential: t

55 h as DNA bases or proteins, possess numerous tautomers and isomers that lie close in energy, making t

56 as an equilibrating pair of interconverting tautomers and not as a single symmetric resonance hybrid

57 as an equilibrating pair of interconverting tautomers and not as a single symmetric structure not on

58 atic resonance structure representations, in tautomers and pericyclic reaction partners in which only

59 In silico modelling of apocynin tautomers and radical species into human NAT crystal str

60 yrrolopyridine analogues, forming up to five tautomers and seven ionization species under experimenta

61 These tautomers and their distinct environmental sensitivity p

62 omer in the wild-type protein to the Ndelta1 tautomer, and an altered motional behavior of the associ

63 on with aldehydes, gave exclusively the keto tautomer, and no isolable enol.

64 fast exchange among the tau tautomer, the pi tautomer, and the cationic state due to proton transfer

65 The H-bonding complexes for 7-H and 9-H tautomers are characterized by higher aromaticity and a

66 While changes in the two tautomers are not large in the Soret band region, the di

67 copy of the HIV-1 primer binding site, both tautomers are observed and show differential sensitivity

68 reduces the enamide preference so that both tautomers are present at equilibrium.

69 e energy differences between the B-N and B-O tautomers are small, explaining the formation of both.

70 om arenols (ArOH), aryloxyls (ArO(*)), their tautomers (ArH), and auxiliary compounds has been invest

71 hemiketal diastereomers, with an open-chain tautomer as a minor component.

72 ropose that the guanine base adopts the enol tautomer as N1 binds to Fe4 and the O6-H hydroxyl group

73 ies, we identified the 2,5-dihydropyridazine tautomer as the releasing species and found factors that

74 tautomers is shifted toward the ketoenamine tautomer, as a result of a conformational change affecti

75 it is difficult to isolate at will a single tautomer, as dynamic equilibria occur easily, even in th

76 ulted in the presence of 100(3)% of the enol tautomer at 300(5) K and 64(5)% of the enol at 671(7) K.

77 imarily forms the common (for histidine) tau-tautomer at neutral pH, while 4-fluorohistidine exclusiv

78 al compartment not to be in the O-protonated tautomer but in the N-protonated tautomer with the preva

79 vated temperatures, the products are not the tautomers but rather dimers stemming from radical-radica

80 t rests on stabilization of the diamino enol tautomer by Dipp substitution, and could be attributed t

81 the result of the stabilization of the enol tautomer by hyperconjugative pai -> sigma*(CF) interacti

82 than the alternative, doubly hydrated trans tautomer by some 8.3 kcal mol(-1) .

83 ractions and the destabilization of the keto tautomer by the electron withdrawal induced by the neigh

84 ly planarized and charge-delocalized enolate tautomers by anion-pi interactions.

85 lexes, while the relative emission of the H3 tautomer can be used to detect single nucleotide polymor

86 nt in comparable amount in solution; the two tautomers can also be selectively precipitated in differ

87 he experimental characterization of a unique tautomer challenging.

88 t intermediate via the 1',4'-iminopyrimidine tautomer, characteristic of all intermediates with a tet

89 that the substrate is present in a hydrazone tautomer conformation.

90 able conformers of the neutral keto and enol tautomers differ by less than 1 kcal/mol in terms of ele

91 Below 50 K, the hs-Co(II) tautomer displays temperature-independent relaxation to

92 spectra and likely reflects variation in the tautomer distribution of the holoenzyme.

93 The tautomer distribution sampled in the gas phase very much

94 dated and then used to obtain pKa values and tautomer distributions for histidine residues of an invi

95 ectron electrophilicity of the Mn(O) valence tautomers dominate OAT reactivity and do not follow the

96 0 nm are resolved, which are ascribed to the tautomer emission resulting from the first and second pr

97 ransfer takes place, rendering a record high tautomer emission yield (0.18 in toluene) and the genera

98 ulting in TA* (560 nm) and TB* (650 nm) dual-tautomer emission.

99 ces in the electric dipole moment of the two tautomers, estimated from density functional theory calc

100 re NMR study suggests existence of the azine tautomer even at higher temperatures with no traces of t

101 d metal ion complexation, where the enol-azo tautomer exhibits much greater affinity for metal ion bi

102 a cyan fluorescence, while the zwitterionic tautomer fluoresces red.

103 The relative stabilities of the tautomers for each series were computed, and the bond le

104 on on the presence of multiple conformers or tautomers for intermediates within a complex reaction pa

105 terior methylenes are present in the favored tautomers for quatyrin.

106 pair, which is ascribed here to a rare enol tautomer form of the thymine, was observed at the end of

107 the base pair radical anions are present as tautomers formed by interstrand PT.

108 implies that the opposite reaction (and the tautomer forming step), a radical-radical disproportiona

109 purported light-adapted state, the glutamine tautomer forms a hydrogen bond with the flavin carbonyl

110 The preference for the enol tautomer further increases in smaller perfluorinated cyc

111 modynamically more favored gaseous phenoxide tautomer, generated from the same aqueous solution of p-

112 polarized when bound to UDG and resembles a tautomer >12 kcal/mol higher in energy.

113 DFT calculations suggest that the observed tautomer has a lower energy than the alternative, doubly

114 The equilibrium between the keto- and enol-tautomers has been extensively studied and quantified in

115 sites of native adenine, complexes with N7-H tautomers have also been considered.

116 and the hydrogen atom affinities (HA) of the tautomers have been used to calculate the reaction entha

117 ons provide structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis, a long-s

118 and defines a sequence context for the "rare tautomer hypothesis" as a mechanism for inducing transit

119 To test the multiple tautomer hypothesis, we used 2D IR spectroscopy, which o

120 cyclic hemiketal tautomer is the most stable tautomer in aqueous solution, followed by the 4-hydroxyc

121 depends on stabilization of a rare cytosine tautomer in C.O6MeG-polymerase complexes.

122 d in hydrogen-bonding solvents and the CH(2)-tautomer in CH(2)Cl(2).

123 llowed by hydrolysis of the enamine or imine tautomer in cis-CaaD versus direct hydration of the alle

124 bond is established, results the most stable tautomer in gas phase (theoretical calculations) and was

125 lts in the increased preference for the enol tautomer in smaller perfluorinated keto-enol systems.

126 AGTT exists as tautomer in solution form and our studies indicate that

127 The existence of each tautomer in solution has been shown to be strongly solve

128 dentification for the active form of the PLP tautomer in the active site of DDC.

129 preparation of the nonaromatic 4H-imidazole tautomer in the core.

130 maticity of the phenol is lost, was the only tautomer in the crystal lattice according to single-crys

131 e participation of the 1',4'-iminopyrimidine tautomer in the mechanism.

132 is22 switches from the predominant Nepsilon2 tautomer in the wild-type protein to the Ndelta1 tautome

133 [6-18O]ImmH to establish that O6 is the keto tautomer in TvPNP x ImmH x PO4, causing an unfavorable l

134 The last form was also found as the main tautomer in UV-vis and NMR spectroscopy when a protic so

135 idual ring and of the whole molecule for all tautomers in ionic complexes is very similar to that obs

136 oncluded that this monoanion is a mixture of tautomers in rapid equilibrium, rather than a single sym

137 nerate protonated 2,4,6-trimethyl-s-triazine tautomers in situ, which undergo Aldol condensation with

138 ical) and "N7" (proton on N7 rather than N9) tautomers in the gas phase, as both are calculated to be

139 Guanine is calculated to have several stable tautomers in the gas phase, in contrast to in solution,

140 lations suggest similar energies for the two tautomers in the presence of water, but the diiminol is

141 he distinct spectral changes between the two tautomers in the Q-band region provide a convenient way

142 ts (hydroquinone, indolequinone, and its two tautomers), in arrangements that contain an interior por

143 n the transient species and is assigned as a tautomer, in which a C6(H) of the transient radical is t

144 gal oxyluciferin regarding its keto and enol tautomers, in the ground and excited states.

145 a are consistent with a substrate imine/enol tautomer intermediate being formed prior to the formatio

146 to be studied whether formation of the keto tautomer is a general feature of all thiamin enzymes, as

147 Formation of the keto tautomer is associated with a loss of aromaticity of the

148 e light (lambda = 400-850 nm), the hs-Co(II) tautomer is formed.

149 whose tautomeric preference toward the azine tautomer is in the range of 3-8 kcal/mol.

150 le proton transfer involving the ketoenamine tautomer is observed after treatment with either gaseous

151 In the dry solid, only the enolimine tautomer is observed.

152 pA)}, only the anti orientation of the imino tautomer is possible.

153 irrespective of the solvent the carboxylate tautomer is preferred in solution, while the opposite ho

154 n less polar CDCl(3) or CD(2)Cl(2), the 6-2H tautomer is stabilized by a strong N-H...O=C intramolecu

155 of -300 mV (vs Ag/AgCl), while the enol-azo tautomer is strongly favored at potentials positive of t

156 The red-shifted H1 tautomer is strongly favored in matched (-)/(+)PBS duple

157 aphthoquinones series indicated that the 1,4-tautomer is the more stable and biologically relevant is

158 that the 4-hydroxycoumarin cyclic hemiketal tautomer is the most stable tautomer in aqueous solution

159 The distribution of cofactor tautomers is dramatically affected by the ligation state

160 carboxylate subsite, the equilibrium between tautomers is shifted toward the ketoenamine tautomer, as

161 Interconversion between individual tautomers is shown to proceed via tight ion-pair interme

162 o a roughly sp(2) type in their carbene keto tautomers, is recognized in one of these pathways (route

163 study of the relative energies of different tautomers, isomers, and supramolecular complexes support

164 On the example of the 7-2H tautomer, it was shown for the first time that the 2H ta

165 verlapping (13)C-satellites, impurities, and tautomers, it has an edge over qHNMR for accurate measur

166 ransfer, to give the poorly emissive excited tautomer [L...H-F](-)*.

167 The interchange among KuQ tautomers leads to substantial spectral variations of th

168 istribution of the enolimine and ketoenamine tautomers, likely as a result of a more polar active sit

169 We assigned the species as an iminoquinone tautomer (LTI) of lysine tyrosylquinone (LTQ), the organ

170 Ph)Ad (3) (R-H = ethylbenzene) or aminoalkyl tautomer [Me(3)NN]Ni(eta(2)-CH(Ph)NHAd) (4) (R-H = tolue

171 E, which is nearly +700 mV above its valence tautomer Mn(V)(O)(TBP8Cz) (Ered = -0.05 V).

172 s ((13)C(gamma), , and ) for each of the two tautomers, N(delta1)-H and N(epsilon2)-H, and the proton

173 odology indicates that the quinolinol (enol) tautomer (not detected by other means) may be accessible

174 arly orthogonal to that of the proposed keto tautomer observed in the S112A.HOPDA complex.

175 Calculations suggested that the dominant tautomer of (Ph)ImC in methanol solution is identical to

176 ental conditions, we have only the canonical tautomer of 1,N(6)-ethenoadenine present.

177 pseudoanisatin, here identified as the chain tautomer of 1.

178 s revealed the first example of a stable cis tautomer of a free-base porphyrin, the long-postulated i

179 Oxanthrone (AnOH) is a more stable tautomer of AnH(2)Q with a ratio of 13 (298 K) in non-hy

180 teristic of the canonical 4'-aminopyrimidine tautomer of bound thiamin diphosphate (AP).

181 he calculations suggest that the nonaromatic tautomer of CAIR (isoCAIR) is only 3.1 kcal/mol higher i

182 omeric equilibrium toward the rare imino-oxo tautomer of cytidine stabilizes the f(5)C34*A base pair

183 hat leads to the formation of an imidic acid tautomer of Gln50.

184 dominantly by binding of the C=C of the enol tautomer of MP to the surface, while simultaneously opti

185 roceeds through the intermediacy of the keto tautomer of naphthol.

186 2C show that the enzyme oxidizes the enamine tautomer of P2C but do not distinguish among several pos

187 he bond between N(1) and C(6) in the enamine tautomer of P2C, ruling out alternative paths that requi

188 DFT calculations of the stable tautomer of selected (Ph)ImC analogues suggested a relat

189 hesized to create models for the 1',4'-imino tautomer of the 4'-aminopyrimidine ring of thiamin dipho

190 s are considered, where * indicates the enol tautomer of the base.

191 {d(ApA)} induces formation of the rare imino tautomer of the bases with a concomitant substantial dec

192 The isoxazol-3-one tautomer of the bicyclic isoxazole, 5,6,7,8-tetrahydro-4

193 C react with benzaldehyde to give the ketone tautomer of the Breslow intermediate, whereas the AAAC f

194 C or mC prior to deamination via an E-imino tautomer of the C or mC or by a nontemplated mechanism i

195 A valence tautomer of the closed-shell Mn(V)(O)(TBP8Cz) can be sta

196 ol the formation of either a keto or an enol tautomer of the products, again resulting in vastly diff

197 The lowest energy tautomer of the protonated form is calculated to be [WOS

198 ation (topomerization) of the "sigma-bonded" tautomers of 1H[B(Ar(F))4], which proceeds according to

199 3)C and (19)F NMR chemical shifts, from both tautomers of 2-fluorohistidine and 4-fluorohistidine in

200 it was shown for the first time that the 2H tautomers of 3-substituted indazoles can be stabilized b

201 Using 2D IR spectroscopy, lactam and lactim tautomers of 6-chloro-2-pyridone and 2-chloro-4-pyridone

202 tom transfer (OAT) reactivity of two valence tautomers of a Mn(V)(O) porphyrinoid complex was compare

203 lculations here show that fC and the neutral tautomers of caC are acidic relative to other TDG substr

204 o the specific contributions of five neutral tautomers of cytosine prior to ionization.

205 he observation and characterization of three tautomers of deprotonated cytosine anions, [trans-keto-a

206 As a consequence, DgAS binds the furanoid tautomers of fructose through a weak network of interact

207 tifies possible pathways involving different tautomers of Gln50 that will eventually lead to the ligh

208 ution we conclude that both dominant neutral tautomers of hypoxanthine exhibit ultrashort excited sta

209 cal intersections for both prominent neutral tautomers of hypoxanthine.

210 present the synthesis of the "missing" keto tautomers of imidazolidinylidene-derived diamino enols,

211 dicating that major gas-phase conformers and tautomers of neutral AA do not support the intramolecula

212 Tautomers of neutral cytosine have been studied in the g

213 osine and suggests a new method to study the tautomers of nucleobases using electrospray ionization a

214 arbaporphyrin structures, together with four tautomers of porphyrin and the related antiaromatic spec

215 Four tautomers of purine (1-H, 3-H, 7-H, and 9-H) and their e

216 Stereochemistry and ring tautomers of the new compounds were investigated by NMR,

217 Tautomers of the nucleobases play fundamental roles in s

218 putational analyses suggest that phenol-type tautomers of the pyrazolone ring are the active pharmaco

219 eroxo, alkylperoxo, and two metal-bound enol tautomers of the unstable dioxygenase product.

220 Intermolecular enol tautomers of Watson-Crick base pairs could emerge sponta

221 perchlorates, electronic isomers (or valence tautomers) of well-known iron(IV)-oxo porphyrin radical

222 undant proportion of this traditionally rare tautomer offers a compelling structure-based mechanism f

223 dynamically less favored gaseous carboxylate tautomer or the thermodynamically more favored gaseous p

224 (2) The rare 1',4'-iminopyrimidine ThDP tautomer participates in formation of ThDP-bound interme

225 d the sample is slowly heated, the hs-Co(II) tautomer persists until ca. 90 K, approximately 40 K hig

226 that P.A. anion binds as the N-deprotonated tautomer (PhSO(2)NOH(-)) to [Fe(II)(N3PyS)](+), leading

227 respectively, along with their corresponding tautomers (PNP)Ti=CHSiMe3(CH2tBu) (5) and (PNP)Ti=CHPh(C

228 The observed switching of the tautomer population occurs within a narrow range of appl

229 This model accurately predicts the relative tautomer populations versus applied potential, at interf

230 the measurement of site-specific pK(a)s and tautomer populations.

231 The enol tautomer possesses Cs symmetry with a planar ring and st

232 )C NMR data, in DMSO-d(6) solution, the 6-1H tautomer predominates, whereas in less polar CDCl(3) or

233 contrast to in solution, where the canonical tautomer predominates.

234 e tautomeric LAH adducts are compared to the tautomer preference energies of the LiH adducts and of t

235 ffinities are reported and used to ascertain tautomer preference.

236 d H/D exchange studies are used to ascertain tautomer prevalence for the 4-phenyl species.

237 ergies (AIEs) of specific gas-phase cytosine tautomers produced in a molecular beam.

238 Hydrolysis of the enamine or an imine tautomer produces acetoacetate.

239 Loss of an acidic proton from these three tautomers produces the same conjugate base structure.

240 s the equilibrium in favor of the oxoenamine tautomer (protonated Schiff base).

241 DFT studies were performed on a series of tautomers, protonated species, and anionic structures re

242 e but complementary quinonoidal and aromatic tautomers provide the Janus faces of the reactants and p

243 afforded the [3,3] electrocyclic ring-opened tautomers, rather than pyrans, in high yields.

244 the course of the ESI process influences the tautomer ratio.

245 polymorphs: 7-1H tautomer (yellow) and 7-2H tautomer (red).

246 adapted state with the imidic acid glutamine tautomer reproduces the experimentally observed spectros

247 nto thermodynamically more stable 1H- and 6H-tautomers, respectively, by removing of the benzyl-PG.

248 The fluorescence quantum yield of the ESIPT tautomers revealed a significant correlation with the ob

249 The same tautomer shift is also induced by heat inactivation of F

250 We propose that the tautomer shift results from loss of a stabilizing H-bond

251 aking the salt bridge, since the rate of the tautomer shift, following CO binding, increases with dec

252 found to diminish the rate and extent of the tautomer shift, suggesting a ketoenamine-stabilizing pho

253 N chemical shift for the 1,4-iminopyrimidine tautomer should serve as useful guides to the assignment

254 ations for each of the rings comprising both tautomers showed that while the central benzene ring los

255 djacent integrals, low-level impurities, and tautomer signals are among the common integral interfere

256 levels of cKAN3H8a(-) and tKAN3H8b(-) yield tautomer-specific resonant photoelectron spectra.

257 Purine tautomer stability increases in the following series: 1-

258 the tris(hydrazone) [rather than tris(azo)] tautomer stabilized by resonance-assisted hydrogen bondi

259 e relative OAT and HAT reactivity of valence tautomers such as M(V)(O)(porph) versus M(IV)(O)(porph(*

260 ry (LC-MS/MS) were hydroxides and their keto tautomers, sulfates, sulfoxides, and N-oxides.

261 s are associated with the normal (N( *)) and tautomer (T( *)) excited-state species that result from

262 ransfer, protonated HAL and ALH rearrange to tautomers that are detected as nondissociated anions in

263 These molecules were isolated as enol tautomers that exhibit intramolecular hydrogen bond and

264 are aromatic, while in the corresponding oxo tautomers the nitrogen-containing ring is essentially no

265 For 9-H and 7-H tautomers the order is reversed.

266 His37 undergoes fast exchange among the tau tautomer, the pi tautomer, and the cationic state due to

267 phy to be exclusively the quinolinone (keto) tautomer, though experimental cyclic voltammetry support

268 ly thermally stable photogenerated hs-Co(II) tautomer, thus providing an excellent handle for molecul

269 n of the pyridyl ligand (or its pyridylidene tautomer) to the alpha-carbon of the vinylidene, followe

270 The reactivity of the valence tautomer (tpfc(+*))Mn(IV)(OH) is compared to that of (tp

271 t we may have a mixture of the keto and enol tautomers under our conditions in the gas phase, althoug

272 hich the proportions of the 5- and 6-methoxy tautomers vary systematically, we demonstrate that solid

273 n forms a mixture of three different valence tautomers (VTs) in CH2Cl2 or 1,2-C2H4Cl2 solutions.

274 CSiMe3)(PMe2Ph) (3a) and its bis(alkylidene) tautomer W(CH2SiMe3)2(=CHSiMe3)2(PMe2Ph) (3b) was simila

275 3(CSiMe3)(PMe3) (1a) and its bis(alkylidene) tautomer W(CH2SiMe3)2(=CHSiMe3)2(PMe3) (1b) has been fou

276 ibration of the thermodynamically disfavored tautomer was attempted with acids and bases but could no

277 In solution, the NH(3)-tautomer was favored in hydrogen-bonding solvents and th

278 heimer-type intermediates as tetrazolopurine tautomers was supported by various spectroscopic methods

279 energetics of neutral and cationic cytosine tautomers were determined using explicitly correlated me

280 No traces of 4-oxoquinoline tautomers were found in the experimental IR spectra, rev

281 Using (TD)-DFT calculations, the tautomers were identified as the H1 and H3 keto-amino ta

282 Both tautomers were isolated as their respective tetrakis(pen

283 constants, K(a)(KH), for the different keto tautomers were measured spectrophotometrically at 25 deg

284 rodiol metabolites, isolated as their ketone tautomers, were obtained from meta and ortho methoxyphen

285 and -10.49 kcal/mol) for less stable purine tautomers when the proton acceptor is located in the fiv

286 l effects favor these conformers of the keto tautomer, which do not support an intramolecular hydroge

287 two fully dechlorinated diastereomers and a tautomer, which further photodegrade over several days t

288 and significant antiaromaticity in the keto-tautomer, which is by no means intuitive.

289 otonation of the metal-stabilized rare imino tautomer, which takes place at pKa approximately 7.5 in

290 the energetic degeneracy of the two valence tautomers, while not affecting the activation barrier.

291 In contrast, 1-naphthol is the preferred tautomer with a Delta(t)H = -9.0 kcal mol(-1).

292 coordinated to the metal ion, but involves a tautomer with a more effective Lewis acid and more react

293 theory calculations showed that a nonplanar tautomer with four internal hydrogens was favored, in ag

294 -protonated tautomer but in the N-protonated tautomer with the prevalence of a keto-enamine resonance

295 C-(P-tetraone)2H leads to the formation of a tautomer with trans inner hydrogens with one residing on

296 Therefore, that enol is a mixture of tautomers with an asymmetric hydrogen bond.

297 Dicarbaporphyrin and tricarbaporphyrin favor tautomers with an internal methylene group, while two in

298 We have investigated all warfarin tautomers with computational and NMR approaches.

299 G reveals the existence of two ground-state tautomers with significantly shifted absorption and emis

300 stallizes in two tautomeric polymorphs: 7-1H tautomer (yellow) and 7-2H tautomer (red).