ライフサイエンスコーパス: technical

1 ting on uterus transplantation outcomes: (1) technical, (2) menstruation, (3) embryo implantation, (4

2 A technical accuracy at bone entry point of 0.48 +/- 0.44

3 MUSTACHE employs scale-space theory, a technical advance in computer vision, to detect blob-sha

4 This study provides a technical advance that will facilitate the study and era

5 nsuming component of wound care with limited technical advancements to date.

6 ia germplasm banking with an overview of the technical advances for feasibility and ensured success.

7 In the past decade significant technical advances have allowed an unprecedented explora

8 Recent technical advances have enabled noninvasive measurement

9 We are again at a turning point at which technical advances have expanded the range of organisms

10 Then, considering recent technical advances in experimental systems and metabolic

11 With recent technical advances in single-cell RNA sequencing (scRNA-

12 Technical advances in the field of microbiome research h

13 Technical advances in ultrasound, including high-resolut

14 Technical advances now allow for the investigation of th

15 Recent technical advances now allow mechanistic studies to move

16 f existing approaches and the conceptual and technical advances that are needed to move forward this

17 Here, we leverage technical advances to resolve the individual protein com

18 s standardisation, together with several key technical advances, enabled a revolution in the speed an

19 is used to highlight the strengths of these technical advances.

20 to genomic DNA and thus promises significant technical advances.

21 This Review discusses the technical advantages and pitfalls of cerebrospinal fluid

22 The present study exploited the technical advantages of the Aplysia sensorimotor culture

23 An expert technical advisory group (TAG), criteria for identifying

24 ion to estimate a manifold that is robust to technical and biological noise found in normalized scRNA

25 xtract latent or hidden signals representing technical and biological sources of variation.

26 In this review, we describe the technical and conceptual advances in the study of durota

27 Recent technical and conceptual advances, such as the establish

28 y originated from ancient cells, and explain technical and conceptual biases that limit our understan

29 Technical and conceptual challenges are considered, alon

30 We also discuss and highlight key technical and conceptual considerations for developing n

31 Topics discussed here include (a) technical and conceptual difficulties in defining a poly

32 ely define the ac(4)C landscape, providing a technical and conceptual foundation for elucidating the

33 d, the concordance in their outputs, and the technical and cost implications of each method were disc

34 ers from renewable resources are deterred by technical and economic challenges; especially, the conve

35 topics based on their significance, urgency, technical and economic feasibility, existing knowledge g

36 professional medical societies, but several technical and ethical issues remain.

37 region could also be prioritised in terms of technical and financial assistance focused on achieving

38 Technical and logistical issues, however, make it challe

39 Technical and material developments adopted from adjacen

40 Over the past decade, technical and methodological improvements in cryogenic e

41 ity development, each of which has different technical and nontechnical configurations that determine

42 Technical and procedural success were higher in MViV.

43 to such alternative solutions requires both technical and social innovations to coevolve over time i

44 uctor emitting in the UV with a multitude of technical applications.

45 ontact efficiency and provides a prospective technical approach to improve the charge density, which

46 er function and the use of a supra-selective technical approach.

47 High-end technical approaches help to untangle the substructure a

48 difications allow researchers to equip their technical arsenal with an interchangeable patch-clamp/ER

49 inherently contain variations introduced by technical artifacts (e.g. batch effects) and uninteresti

50 ssume the existence of zero inflation due to technical artifacts and attempt to impute the missing in

51 from these methods are used to discover both technical artifacts and novel biological phenomena.

52 ed that cancer subtypes and ancestry-related technical artifacts are important confounders that have

53 olyploid organisms usually either (i) assume technical artifacts are known a priori or (ii) estimate

54 rtifacts are known a priori or (ii) estimate technical artifacts simultaneously with the prior genoty

55 ng insight into the biological processes and technical artifacts that led to the disagreements in the

56 of this development community by addressing technical aspects (like version control, testing, and ma

57 pecies was challenged by both biological and technical aspects coupled to the ecology of eDNA and the

58 This review covers the technical aspects of integrating CRISPR/Cas technology i

59 heart-liver transplantation (HLTx), describe technical aspects, and discuss benefits of the technique

60 from 30 healthy volunteers were used for the technical assessment of the IPP tool.

61 igns, surveillance and laboratory resources, technical assistance, social mobilization, treatment, an

62 arcely used in fetal echocardiography due to technical assumptions and issues of reliability.

63 This study was aimed at overcoming the technical barrier by developing a paper-based isotachoph

64 However, technical barriers to tracking a large number of these r

65 oped to combine diverse datasets by removing technical batch effects, but most are computationally in

66 we detected differences in susceptibility to technical bias.

67 y of the instrument, experimental design and technical bias.

68 ticle aims to review recent developments and technical breakthroughs including optical, electrochemic

69 Furthermore, we outline conceptual and technical breakthroughs that can be applied to existing

70 , tumor heterogeneity presents a significant technical challenge for most cancer genomics studies per

71 a self-correcting design to overcome the key technical challenge of reinforcement learning from imper

72 A technical challenge to accurately quantify the FAF inten

73 s(t)ide analogues therapy still represents a technical challenge.

74 e to sample input in heart tissues remains a technical challenge.

75 e active synapses in brain tissue has been a technical challenge.

76 We also outline technical challenges and solutions to conducting cell ty

77 uminate the rationales for sharing data, the technical challenges and the social and cultural challen

78 resolution metabolic imaging, but comes with technical challenges due to non-uniform B(0) field.

79 Together with discussion on technical challenges for this REBCO shim coil concept, w

80 lites and lipids across tissue surfaces, but technical challenges have limited the application of IMS

81 However, technical challenges have limited the recognition and un

82 However, technical challenges must be overcome to routinely lever

83 thermophilic archaea has been limited by the technical challenges of imaging at high temperatures.

84 Given the technical challenges of studying these dynamic proteins,

85 Once the technical challenges of such a coupling are overcome, in

86 ascent discipline are presented, and ongoing technical challenges related to manufacturing, storage,

87 However, a number of technical challenges still exist, such as interferences

88 Future studies will need to address technical challenges such as how to accurately measure i

89 This method overcomes several major technical challenges that have prevented HIV sequencing

90 alized, there are a number of logistical and technical challenges that must be overcome.

91 n this work, we overcome these practical and technical challenges with RLC circuits, transcending exi

92 iscussion of the newly enabled applications, technical challenges, and future outlooks are provided f

93 Yet, ongoing questions, technical challenges, and unresolved controversies relat

94 tion of chemicals, but they face a number of technical challenges, including product toxicity and/or

95 ethods, with an emphasis on highlighting the technical challenges, key lessons learned, and new oppor

96 cult to obtain because of several formidable technical challenges, such as poor recording stability a

97 complexity of this workflow poses formidable technical challenges, thus limiting wider applications o

98 o techniques have not been correlated due to technical challenges.

99 outline a road map for overcoming remaining technical challenges: identifying high-risk pathogens be

100 targeted by an intervention, but also on the technical characteristics of the intervention and the cu

101 opment of the elephant in the room, that is, technical cognition.

102 Technical complexity increased over time as evidenced by

103 While technical complexity increased over time, post-operative

104 red by 2D-IR spectroscopy outweigh the added technical complexity of the measurement.

105 involves positive feedback whereby increased technical complexity selects for enhanced social learnin

106 predefined postoperative medical or surgical technical complications.

107 B and the present time has witnessed several technical, computational and conceptual advances in gene

108 We also discuss technical considerations for in vivo neuroepigenome-edit

109 targeting of Na(V)1.9, although hampered by technical constraints, might also be moving ahead.

110 cell-autonomous, and not simply a result of technical contamination or paracrine transfers of mRNAs,

111 Measures are needed to reduce technical, decision-making, and administrative factors.

112 Methods: In this work, a technical description of simplified dose estimation is p

113 ecifically, in this protocol, we provide the technical details and precise instructions for translati

114 ion will be promoted by dissemination of the technical details for assembling the FPOP platform and f

115 Technical detection cutoffs showed a 4 log range (0.001%

116 a compound and the later type is caused by a technical detection limit.

117 , we provide a comprehensive overview of the technical development of DBS, from its origins to its fu

118 Technical developments are unifying molecular and cellul

119 y(4)-and their critical roles in present-day technical devices.

120 ttributed to both enhanced visualization and technical dexterity.

121 eter is released here as open hardware, with technical diagrams, a full parts list, and source code f

122 gradually removes batch effects, as long as technical differences across batches are smaller than tr

123 of CyTOF datasets remains a challenge due to technical differences arising in multiple batches.

124 This goal has been hampered by technical difficulties and the challenge of obtaining fr

125 acteria compared to model organisms, and the technical difficulties of metagenome assembly and phasin

126 strategy that overcomes some of the existing technical difficulties.

127 mic and subgenomic contexts, which given the technical difficulty of experimentally separating cellul

128 One of the reasons for that is the relative technical difficulty of the generation of well-defined g

129 tep that adjusts for unwanted biological and technical effects that can bias the signal of interest.

130 ed repeat ablation, resulting in a secondary technical efficacy (STE) rate of 90.2%.

131 fully ablated at initial SRFA (80.5% primary technical efficacy rate (PTE)).

132 Endpoints consisted of (i) technical efficacy; primary - requiring one treatment, a

133 s not studied before, revealing 38 different technical elements, as well as community-specific combin

134 % of PCCRCs was determined to be affected by technical endoscopic factors, 17% of PCCRCs by administr

135 Here, we aimed to detect anomalies caused by technical errors in water-quality (turbidity and conduct

136 However, despite the tremendous technical evolution of transcatheter heart valves, to da

137 THe HRSA held a 1-day Technical Expert Panel (TEP) to explore how RWHAP can be

138 ment was developed using a multidisciplinary technical expert panel, targeted literature reviews, sim

139 hand, intermediate or difficult LLRs require technical expertise and an oncological benefit can only

140 hemselves-which typically requires extensive technical expertise-and allows them to focus on their sc

141 Taken together, we unravel a technical explanation for discrepancies in the published

142 Considering the requisite biological and technical factors for elimination, effective interventio

143 ng noise in signal profiles and accounts for technical factors such as sparse signals, mappability an

144 physiological, cognitive, environmental, and technical factors, and by the types of mobilities and di

145 inations failed (lymphoma in one patient and technical failure in one patient).

146 No technical failure or retention occurred.

147 These studies investigated the technical feasibility of using the primate mini-EXPLORER

148 However, RNA-seq has technical features that incumbent tests (e.g. t-test and

149 A comprehensive perspective of the technical framework of the state-of-the-art RBC-mediated

150 A significant technical hurdle for HCP analysis is the overwhelmingly

151 -1/PC-2 polycystin complex is lacking due to technical hurdles in reliably measuring its activity.

152 Perioperative data, technical information, treatment outcomes and follow-up

153 learning is essential for humans to acquire technical information.

154 lease of the PRIDE database with an improved technical infrastructure, a new API, a new webpage, and

155 Furthermore, besides technical innovations and probes, emerging clinical indi

156 We also discuss technical issues for converting the FRET-based cyclizati

157 Here, we discuss the technical issues related to the determination of the nuc

158 , whereas 'desirable' information relates to technical issues that might be encountered when repeatin

159 their models in Brian, without requiring any technical knowledge about GPUs, C++ or GeNN.

160 pproach to generating evidence through socio-technical "lighthouse" projects that apply alternative u

161 e due to the complex nature of the cells and technical limitation in analysis.

162 natomical factors influence g(m) , (iii) the technical limitation of estimating g(m) , which cannot b

163 stem but in ways that are unclear because of technical limitations (anesthesia, nonselective neuronal

164 nt has been challenging to study due to both technical limitations and ethical restrictions.

165 lap likely stems from biological rather than technical limitations as most synthetic lethal phenotype

166 tion of these activation mechanisms and that technical limitations can bias interpretation.

167 s have been identified as neurotransmitters, technical limitations have precluded a full metabolomic

168 High cost, intensive labor requirements and technical limitations hinder the cell composition quanti

169 ty and its neural circuitry, the ethical and technical limitations in exploring neural underpinnings

170 variability between experimental set-ups and technical limitations of Hz generation and isolation met

171 In addition, technical limitations of incomplete dystrophin gene exci

172 eas of head-fixed or tethered rodents due to technical limitations of recording from larger freely-mo

173 meaningful glycoproteomic undertakings, many technical limitations remain unsolved.

174 logical DSTs for PZA have been restricted by technical limitations, especially the necessity for an a

175 However, because of technical limitations, scRNA-seq data often contain zero

176 alth correlations, due to methodological and technical limitations, they have been unable to directly

177 ng difficult in newborns due to economic and technical limitations.

178 s due to inconsistent results occurring from technical limitations.

179 conditioned host has not been studied due to technical limitations.

180 hat this pattern arises almost entirely from technical limitations.

181 s of invertebrates is unknown, partly due to technical measurement issues associated with small body

182 gether, deciding publication on the basis of technical merit alone.

183 notype-Tissue Expression (GTEx) datasets and technical metadata along with RNA-seq datasets from othe

184 ay-old, wild-type larval tail, and implement technical modifications to measuring muscle physiology i

185 n oncology given the multifaceted and highly technical nature of this field of medicine with a heavy

186 A technical need is in efficient, generalized inverse desi

187 transcribed point mutations and accounts for technical noise and expression stochasticity.

188 these scores under the null of uncorrelated technical noise has an accurate gamma approximation, bot

189 ogeneity, but the results may be obscured by technical noise inherent in the experimental procedure.

190 ble biological signal from data corrupted by technical noise remains a prevalent open problem.

191 ations, stochastic transcription errors, and technical noise, impeding efforts to elucidate the mecha

192 rement must not be significantly affected by technical noise, such as intensity fluctuations, which a

193 that is then normalized and scaled to remove technical noise.

194 ensitivity at low coverage by accounting for technical noise.

195 nced with intraoperative performance topics: technical, nontechnical, and teaching skills.

196 In this technical note, the two approaches are evaluated in comb

197 Our methodology introduces several technical novelties to tackle the OCT frame misalignment

198 ility of large genomics datasets by removing technical obstacles to independent exploration.

199 otic scRNA-seq pipeline that overcomes these technical obstacles.

200 The effect is uncertainty as to which technical offerings meet legal standards.

201 r, commercial brand name, detection methods, technical operational details, detection time, clinical

202 enarios, and integrated design) and emerging technical opportunities that we argue need to be conside

203 tient comorbidities, anatomical factors, and technical or procedural considerations.

204 n of Bell inequality parameters with minimal technical overhead, and for new characterization methods

205 t was used to establish the optimal mf3D-MRE technical parameters for NASH detection.

206 ry to calibrate it properly and to check its technical parameters.

207 Surgical-technical partnerships should be encouraged to develop a

208 Technical performance during combined suturing and decis

209 y a central role in diagnosis and have fixed technical performance metrics.

210 Altogether, we provide a historical and technical perspective and discuss future directions and

211 With advances in the technical platforms used for cardiomyocyte maturation re

212 eration is an important consideration from a technical point of view.

213 luorescent Wnt-3a reported here opens up the technical possibilities to unravel the intricate biology

214 Interrelations between technical potential and expertise leave it unclear exact

215 extant scientific approaches to quantify the technical potential and externalities of SCS measures, a

216 The technical potential to reconcile these roles by concentr

217 Method validation demonstrates good technical precision (CV = 7.7%, n = 45) and accuracy wit

218 Technical problems intrinsic to the purification of prer

219 Additionally, the scientific issues and technical problems that hinder further development of th

220 problem, owing to the complex biological and technical processes that give rise to observed transcrip

221 We established a clinical and technical protocol for repeated home collection of blood

222 allenge their position by arguing that human technical rationality is unintelligible outside of our s

223 volutionary account of the interplay between technical reasoning and social learning, with language e

224 pth discussion on the role of what they term technical reasoning in cumulative culture, we argue that

225 We argue that technical reasoning is not quite the magic bullet that O

226 atter are recombined, they are perceived as "technical reasoning," resulting in novel tools when exec

227 ing multiple methodologies and examining how technical-reasoning develops in children will provide cr

228 we reply to these concerns, discuss why the technical-reasoning hypothesis does not minimize the rol

229 expertise leave it unclear exactly what the technical-reasoning hypothesis encompasses.

230 By the technical-reasoning hypothesis, cognitively-impaired ind

231 her possibility is that accumulation of both technical-reasoning skills and enhanced social skills st

232 mulative technological culture originates in technical-reasoning skills is not the only alternative t

233 social-learning mechanisms - nor assume that technical-reasoning skills make individuals omniscient t

234 tied to nonsocial cognitive skills, namely, technical-reasoning skills, which allowed humans to cons

235 We report technical refinements, including removal of extracellula

236 ddressing local access challenges, including technical, regulatory, affordability, and other healthca

237 s a foundational research tool, but a recent technical renaissance has facilitated high-yielding (gra

238 f a single SPME fiber device for up to three technical replicate measurements of one sampling event.

239 sample and reagent consumption with up to 50 technical replicates per sample.

240 dimensional cytometry datasets, even without technical replicates.

241 reproducibly with minimal variations between technical replicates.

242 and experimental variations among biological/technical replicates.

243 e also provide a detailed description of the technical requirements and procedures for building the s

244 e International Council for Harmonisation of Technical Requirements for Registration of Pharmaceutica

245 -Immunology Practice Parameters to provide a technical review to be used as the basis for an updated

246 To inform the clinical guidelines, this technical review was completed in accordance with the Gr

247 This technical review was developed using the Grading of Reco

248 cade are summarized, potentially providing a technical roadmap for the next wave of innovations and b

249 d metal with tailored dimensions has been of technical significance in nano-electronics while a chall

250 Technical skill was objectively assessed using task prog

251 more often on nontechnical skills (60%) than technical skills (32%) or teaching-specific skills (8%).

252 efits of ad hoc efforts go beyond developing technical skills and may provide continued benefit in co

253 as much on professional relationships as on technical skills or contracts.

254 These decisions are easier to replicate than technical skills or system factors.

255 this simulation is a useful adjunct for both technical skills training and formative Deanery or Facul

256 ring were determined and recommendations for technical skills training, proctoring, and performance a

257 ve errors and events, variation in surgeons' technical skills, and a high amount of environmental dis

258 for research questions to be addressed from technical, social, and transformative perspectives.

259 needs for further development, and possible technical solutions available through molecular allergol

260 Available technical solutions for creating professional local samp

261 rmore, current systems suffer from a lack of technical solutions for sequential measurements of multi

262 stroke recognition, and deployment of novel technical solutions such as smartphone applications, tel

263 Agronomical or technical solutions to selectively decrease the amount i

264 resource for this, as a generic platform of technical solutions to tackle complex medical challenges

265 dges to the total release offers options for technical solutions which have the possibility to contro

266 rch can help characterize risks and evaluate technical solutions.

267 ditionally, scRNA-seq datasets often contain technical sources of noise owing to incomplete RNA captu

268 Technical standardization is the only way to obtain an o

269 eripheral myelin have fallen behind evolving technical standards.

270 The FRS has been utilized to identify technical strategies associated with reduced CR-POPF inc

271 Four recipients with a technical success in phase 1 have delivered 1 or 2 babie

272 or 2 babies, and the fifth recipient with a technical success is >30 weeks pregnant.

273 s included device-related adverse events and technical success of stent deployment.

274 xcellent safety profile, and associated high technical success rate during deployment.

275 The technical success rate in both groups was 100%.

276 Overall technical success rate of stent deployment was 99.2%.

277 rates (post automated reprocessing) and ERCP technical success rates.

278 Technical success was achieved in 18 (90%) patients and

279 Technical success was achieved in 98% (58/59 tubes).

280 Contrast-enhanced MRI was evaluated for technical success, depiction of pathologic abnormalities

281 ained favored over plausible recent range of technical success.

282 ealthcare worker education and training, (2) technical support for the implementation of evidence-bas

283 n conceptions in software engineering, socio-technical systems engineering, and a neurocognitive theo

284 or networks, and conceptualize them as socio-technical systems that can address resource management c

285 ddress some aspects of this question using a technical tour de force approach to systematically evalu

286 This practical and technical update on a representative group of establishe

287 to coevolve over time into integrated socio-technical urban water systems.

288 The GUI was designed to be intuitive for non-technical users to perform various statistical functions

289 In the technical validation stage, miRNAs with altered expressi

290 were also found to be deregulated in feces (technical validation).

291 eous CT scanning protocols and the resulting technical variability (eg, different slice thicknesses,

292 scRNA-seq data are much noisier due to high technical variability and low sequencing depth.

293 The technical variability introduced by slide preparation an

294 The marked technical variability, high amounts of missing observati

295 to account for the different cell count and technical variability.

296 o existing methods when there is significant technical variation in the generation of the reference p

297 e annotated we report here 185 that showed a technical variation of x < 30%.

298 of the same treatment group may occur due to technical variation or true biological differences.

299 better accounting for the uncertainty due to technical variation.

300 85) in a 1:1.15 ratio to accommodate for 15% technical vein of Marshall ethanol infusion failures.