ライフサイエンスコーパス: telomere sequence

1 in control DNA lacking the specific TG-rich telomere sequence.

2 selectively bind and cleave the G-quadruplex telomere sequence.

3 T1-TPP1 proteins compared with the wild-type telomere sequence.

4 een the many G-quadruplex folds of the human telomere sequence.

5 chromosome immediately before the integrated telomere sequence.

6 estrict potential registrations of the added telomere sequence.

7 rrangements confirmed the involvement of the telomere sequence.

8 unique Not I site from 0.7 kb of Tetrahymena telomere sequence.

9 LC1) to produce (TTAGGG)n repeats, the human telomere sequence.

10 mere elongation, that led to a non-canonical telomere sequence.

11 tuting mutant telomerase that adds a variant telomere sequence.

12 hromosome termini without the use of natural telomere sequences.

13 h Form 1 and Form 2 adopted by natural human telomere sequences.

14 genome and/or in subgenomic targets such as telomere sequences.

15 f hTERT is required to promote elongation of telomere sequences.

16 otide, and several quadruplexes derived from telomere sequences.

17 225 or 180 kb long, containing both sod2 and telomere sequences.

18 None of the BFB breakpoints had telomere sequences added to resolve the dicentric chromo

19 meres have unveiled unexpected divergence in telomere sequence and architecture, and the proteins tha

20 tion, with two separate reactions amplifying telomere sequence and reference single copy gene (riboso

21 for its ability to form telomeres from human telomere sequence and to stably maintain long stretches

22 dentifying homology with previously reported telomere sequences and human repeat elements, gene seque

23 were derived from genic, retrotransposon, or telomere sequences and were not deleted from the donor s

24 Somatic cells generally do not maintain telomere sequences, and these cells become senescent in

25 sm demonstrated that spectra from the native telomere sequence are characteristic of a G-quadruplex s

26 ntramolecular G-quadruplexes formed by human telomere sequences are attractive anticancer targets.

27 gile telomeres in ALT cells, suggesting that telomere sequences are prone to replication problems.

28 Telomere sequences are subtly altered in est2-LT strains

29 tained a human Alu sequence at one end and a telomere sequence at the other end (Alu-CEN-M1-TEL and A

30 Telomerase extends telomere sequences at chromosomal ends to protect genomi

31 Surprisingly, this revealed long telomere sequences at the virus-subtelomere junction tha

32 rosophila melanogaster, which lacks specific telomere sequences but nonetheless assembles terminal he

33 While the human telomere sequence (C3TAA)3C3 assumes i-motif structure a

34 The G-quadruplex for the human telomere sequence consisting of a repeating d(TTAGGG) is

35 Telomere length (TL) was assessed as the telomere sequence copy number (T) compared to a single-c

36 X-ray crystallographic studies on the human telomere sequence d[AGGG(TTAGGG)3] revealed a unimolecul

37 G-quadruplex formed from the Oxytricha nova telomere sequence, d(G4T4G4), has been solved to 1.55 A.

38 Similarly, the telomere sequence did not alter the rate or distribution

39 The telomere sequence did not induce chromosome truncation a

40 In one orientation, the deposited telomere sequence did not interfere with expression of t

41 es but lack the unique features of a natural telomere sequence, do not terminate BIR at a significant

42 These results suggest that mutant telomere sequences elicit a checkpoint that is genetical

43 Recently, four-repeat human telomere sequences have been shown to form two different

44 and a related budding yeast with a degree of telomere sequence homology that is similar to human telo

45 Structures formed by human telomere sequence (HTS) DNA are of interest due to the i

46 Changes in the telomere sequence impair shelterin binding, initiate a D

47 hTRF (human TTAGGG repeat factor) binds the telomere sequence in vitro and localizes to telomeres cy

48 ed human telomere and several modified human telomere sequences in potassium-containing solutions.

49 ssettes on both arms show instability of the telomere sequences in S.cerevisiae at a frequency of app

50 tered so that telomerase adds the vertebrate telomere sequence instead of the yeast sequence to the c

51 a suggest that the irregularity of the yeast telomere sequence is because of the template sequence of

52 tanding of the proteins interacting with the telomere sequence is lacking.

53 lly, we show that a 48-nucleotide DNA with a telomere sequence is more susceptible to nuclease digest

54 how that when BIR encounters an interstitial telomere sequence (ITS), the machinery frequently termin

55 Schizosaccharomyces pombe cells can survive telomere sequence loss by continually amplifying and rea

56 cted from short-read sequencing, thus making telomere sequencing, mapping, and variant resolution cha

57 s as to how incorporation of a non-canonical telomere sequence might alter telomere length dynamics.

58 elomeres, discover and localize noncanonical telomere sequence motifs (both previously reported, as w

59 leotides were able to compete with the human telomere sequence oligonucleotide for binding to a speci

60 ermine the effects of a defined interstitial telomere sequence on chromosome instability, as well as

61 so suggest a plausible explanation why human telomere sequences predominantly form hybrid-I and hybri

62 um pH for the ligation reaction of the human telomere sequence ranges from 4.5 to 6.0.

63 ion forks at telomeres and internally placed telomere sequences, regardless of whether the telomeric

64 recombination event between the two pMAX-121 telomere sequences, resulting in a linear molecule.

65 The constructs contain 0.8 kb of human telomere sequence separated by a unique Not I site from

66 The characterization of unusual telomere sequence sheds light on patterns of telomere ev

67 rmal template boundary, resulting in altered telomere sequences, telomere shortening, and cellular gr

68 ccharomyces cerevisiae contains an irregular telomere sequence (TG1-3)n, which differs from the regul

69 cell division, whereas telomerase elongates telomere sequences to compensate for losses that occur w

70 osition on a chromosome is not necessary for telomere sequences to localize to the bouquet; and (c) b

71 We used quantitative PCRs and a telomere-sequence to single-copy-gene-sequence ratio met

72 thesizes the multikilobase repeating hexamer telomere sequence (TTAGGG)n at the ends of chromosomes.

73 ating that there is an internal array of the telomere sequence (TTAGGG)n in the PAR.

74 ic repeats (TMRs) that are identical to host telomere sequences (TTAGGG).

75 The telomere sequence, TTAGGG, is conserved across all verte

76 ngth, and less than the value found with the telomere sequence under conditions that inhibit quadrupl

77 -derived homozygous line HFTH1, including 22 telomere sequences, using a combination of PacBio single

78 Remarkably, the mutant telomere sequence was different from that of wild-type c

79 res or fused together after complete loss of telomere sequences) was observed within 26 hours of C-10

80 p us understand why the G-quadruplex forming telomere sequences were adopted by almost all eukaryotic

81 lex secondary structure, whereas the altered telomere sequences were devoid of these signatures.

82 Telomere sequences were quantified by real-time polymera

83 gh distant from the template, ensures proper telomere sequence, which in turn promotes proper assembl

84 mammalian cells that correlate interstitial telomere sequence with sites of spontaneous and radiatio

85 3 DNA-binding domain (Cdc13-DBD) binds these telomere sequences with high affinity (3 pM) and sequenc

86 Human telomere sequences with two phosphate groups, one each a