コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 g315Leu, indicating that these mutations are temperature sensitive.
2 development rate, and vector competence are temperature sensitive.
3 renders yeast cells rapamycin resistant and temperature sensitive.
4 pathogenic Cx31 mutants are un/misfolded and temperature sensitive.
5 136 kJ mol(-1), HMF formation being the most temperature sensitive.
6 e modification of OsFIE1 were observed to be temperature sensitive.
7 aeruginosa chronic infection isolate 2192 is temperature sensitive.
8 morphic alleles, and another two mutants are temperature sensitive.
9 other key biochemical processes appear more temperature sensitive.
10 ed (CPD) versions of RSV were attenuated and temperature-sensitive.
11 We allowed all five steps in the cycle to be temperature-sensitive.
12 tissue, and many physiological processes are temperature-sensitive.
13 The mutant phenotype is also temperature-sensitive.
14 dization processes, which are expected to be temperature-sensitive.
16 ase A (ACA) with SQ22536 and incubation of a temperature-sensitive ACA mutant at the restrictive temp
23 in S. pombe We show that the lethality of a temperature-sensitive allele of eso1 (eso1-H17) is due t
25 chemical mutagenesis screen, we identified a temperature-sensitive allele of the gene encoding DNA po
28 P417L or P417S as the only copy of Ssa were temperature sensitive and exhibited defects in Ssa1-depe
29 stabilized vaccine candidate was moderately temperature sensitive and had a level of restriction in
30 g evidence that mutations at these sites are temperature sensitive and highlighting the importance of
31 Results show that heart fibres were more temperature sensitive and increased respiration rate wit
32 demonstrate that this process is remarkably temperature sensitive and mediated through intracellular
33 tures at low temperature, as inactivation of temperature-sensitive and cold-sensitive ded1 mutants ga
38 nuclear migration in unc-84 null animals is temperature sensitive; at 25 degrees migration fails in
39 function of inner hair cell ribbon synapses (temperature-sensitive auditory neuropathy) or auditory n
42 omyces cerevisiae that allowed a recovery of temperature-sensitive but respiratory competent zim17 mu
43 1 neurons) were artificially activated via a temperature-sensitive cation channel (dTRPA1), males fol
46 anilloid 1 and 4 genes (trpv1, trpv4) encode temperature-sensitive cation channels hypothesized to me
52 r system provides opportunities for studying temperature-sensitive chemical, biochemical, and biologi
54 ed with a near-infrared emissive oxygen- and temperature-sensitive chromium(III) complex ([Cr(ddpd)(2
55 he six internal protein gene segments of the temperature sensitive, cold-adapted (ca) A/Ann Arbor/60
57 es low surfactant emulsion formulations with temperature-sensitive compounds, is scalable to industri
61 Here we investigated the critical period for temperature-sensitive courtship rate plasticity in the b
65 d against deattenuation, specifically, a non-temperature-sensitive deletion mutation involving 6 nucl
66 two orders of magnitude, owing to the highly temperature-sensitive diffusion between aggregated DNA-c
67 ell extravasation within tumors treated with temperature-sensitive doxorubicin and ultrasound hyperth
68 riving expression of the gene coding for the temperature sensitive dTRPA1 channel, yielded a single l
70 o exacerbate other environmental problems in temperature-sensitive ecosystems (e.g., coral bleaching,
72 TEs of >600 mRNAs, whereas inactivation of a temperature-sensitive eIF4A variant encoded by tif1-A79V
73 ght sensitivity using gold nanorods bound to temperature-sensitive engineered transient receptor pote
77 , the observation of striking differences in temperature-sensitive expressions, testicular physiology
78 tional mutation in the cdkg1 gene leads to a temperature-sensitive failure of meiosis in late Zygoten
80 we screened for extragenic suppressors of a temperature-sensitive fission yeast strain mutated in th
81 rmal gradients by changes in fluorescence of temperature-sensitive fluorescent dyes need to account f
82 on human CFTR, the F508del mutation caused a temperature-sensitive folding defect, which disrupted ov
84 rprisingly, the recombinant CPD viruses were temperature-sensitive for replication in vitro (level of
85 BSI: 5 have been previously described in non-temperature-sensitive forms of congenital ichthyosis (Ar
87 rA and DrrB proteins expressed together in a temperature-sensitive ftsH mutant strain of Escherichia
88 Here, we combined the Gal4/UAS system and a temperature-sensitive Gal80 molecule to induce RNAi-medi
89 The physicochemical underpinnings of this temperature-sensitive gating have proven difficult to pa
92 10, Saccharomyces cerevisiae cells exhibit a temperature-sensitive growth defect under oxidative grow
95 hosphomimetic cse4-4SD mutant suppresses the temperature-sensitive growth of ipl1-2 and Ipl1 substrat
96 rms based on their ability to complement the temperature-sensitive growth phenotype of Escherichia co
98 BI in the context of a bcmd-RGFlu carrying a temperature-sensitive H1N1 virus resulted in protection
99 , we report the generation of a recombinant, temperature-sensitive H3N8 CIV as a live-attenuated infl
100 10-bp gene that codes for a homologue of the temperature-sensitive hemagglutinin (Tsh) autotransporte
101 ers of photo-crosslinkable copolymers with a temperature-sensitive hydrogel as the middle layer.
102 d that the timing of chromatin compaction is temperature sensitive in both wild type and synMuv B mut
104 arge peptide pool, subsequently refined by a temperature-sensitive induced-fit mechanism to retain th
106 n of Escherichia coli, which is dependent on temperature-sensitive interdomain unfolding and cis-tran
116 diated nanoparticles were quantified using a temperature sensitive lipid-based assay and compared to
117 oteridol was enhanced in tumors treated with temperature-sensitive liposomal doxorubicin and ultrasou
120 ted whether enhanced therapeutic activity of temperature sensitive liposomes (TSL) could be obtained
124 design principles around the construction of temperature-sensitive liposomes (TSL) and their use in c
125 n, hyperthermia-triggered drug delivery from temperature-sensitive liposomes (TSLs), and combinations
129 ty, we stabilized doxorubicin with copper in temperature-sensitive liposomes that rapidly release fre
130 behavior, and clinical potential of various temperature-sensitive liposomes, as well as the various
132 ne expression on virus pathogenesis, using a temperature-sensitive, live-attenuated 2009 pandemic H1N
133 eal of work has been dedicated to developing temperature sensitive macromolecules that can be crafted
137 n-coding gene segments from the cold-adapted temperature-sensitive master donor virus A/Ann Arbor/6/1
139 methods cannot join ceramics in proximity to temperature-sensitive materials like polymers and electr
140 r, we find that the response is different in temperature-sensitive mcm4 mutants, affecting a subunit
141 Mathematical modeling further supports a temperature-sensitive mechanism to protect a subset of t
142 ser beam at-a-distance was found to activate temperature-sensitive membrane receptors, resulting in a
143 We then validated and narrowed our list of temperature-sensitive microbes by comparing the results
145 rticular, the Northern Hemisphere network of temperature-sensitive millennial tree-ring chronologies,
147 eveloped plasmid constructs that overexpress temperature sensitive miRNAs: miR-34a, miR-451, and miR-
148 produced in a single step by exploiting the temperature-sensitive miscibility of hydrocarbon and flu
150 pen reading frames (ORFs) (C(Delta170)) or a temperature-sensitive missense mutation in the L ORF (L(
152 Selection drove complete replacement of the temperature-sensitive mitochondrial genome by a wild-typ
153 may serve as the basis for developing other temperature-sensitive models for the study of recessive
154 spatial and temporal control of Filamenting temperature sensitive mutant Z (FtsZ) Z-ring formation i
155 ees C with those in the widely used pat1-114 temperature-sensitive mutant at 34 degrees C, a temperat
157 tivity on the functional conformation of the temperature-sensitive mutant cystic fibrosis channel (F5
158 Genetic analysis of the outer core in a temperature-sensitive mutant demonstrated this core func
159 ream region of highly transcribed genes in a temperature-sensitive mutant of Clp1 at elevated tempera
160 e characterized the growth of a B1-deficient temperature-sensitive mutant virus (Cts2 virus) in U2OS
163 eukaryotic tubulin and bacterial filamenting temperature-sensitive mutant Z protein (FtsZ) polymers.
164 thesized Gp0.4 binds to purified filamenting temperature-sensitive mutant Z protein and directly inhi
168 ng upshifts to nonpermissive temperatures in temperature-sensitive mutants of cell-wall synthesis enz
171 were used to screen a targeted collection of temperature-sensitive mutants to identify mutations that
174 ased temperature imposed selection against a temperature-sensitive mutation affecting cytochrome oxid
175 the flagella of fla10-1 cells, which carry a temperature-sensitive mutation in the anterograde motor
179 f the UTRs together with the introduction of temperature-sensitive mutations in both the nucleocapsid
180 subgenic M polypeptides, by incorporation of temperature-sensitive mutations in the N and L genes, an
181 hing suit ichthyosis is caused by recessive, temperature-sensitive mutations in the transglutaminase-
182 encoding the NSs protein and introduction of temperature-sensitive mutations, in the design of attenu
186 It is still unknown whether and how these temperature-sensitive neurons are involved in thermoregu
188 lobal transcriptome analysis reveals a major temperature-sensitive node of SA signalling, impacting 6
190 tion mutant of stO1, we demonstrate that the temperature-sensitive O-antigen production defect in 219
193 varian tumor cells expressed a heterozygous, temperature-sensitive p53(V172F) mutation, which reduced
194 e find that the drug-metal complex formed in temperature-sensitive particles can be internalized by c
195 der to design protocols for the use of these temperature-sensitive particles in cancer treatment, the
196 is required to inactivate the commonly used temperature-sensitive Pat1 kinase mutant (pat1-114).
197 the incubation temperature during a critical temperature sensitive period (TSP) determines sexual fat
199 specifically to determine if the attenuating temperature-sensitive phenotype can revert and, if so, t
200 g required for the protein to complement the temperature-sensitive phenotype of an spo7Delta mutant s
201 n allele-specific manner, (b) suppresses the temperature-sensitive phenotype of both groES and groEL
202 ns and PVR-Tg21 transgenic mice, loss of the temperature-sensitive phenotype, and the capacity for su
203 ng the H3N2 NS1-V194I protein demonstrated a temperature-sensitive phenotype, further attenuating the
204 sequences partially suppresses the bdf1Delta temperature-sensitive phenotype, suggesting that maintai
209 sect pest, Drosophila suzukii, by creating a temperature-sensitive point mutation in the sex-determin
214 temperatures above 30 degrees C suggesting a temperature-sensitive process that slows impulse propaga
215 change is likely to increase the rate of the temperature-sensitive processes that decompose stored or
216 s can exploit degenerate relationships among temperature-sensitive processes to achieve robust functi
217 We show that R1108C and R1129C are both temperature-sensitive processing mutants that engage the
218 ccharide-based systems with inherent pH- and temperature-sensitive properties, as well as enzyme-clea
221 ated at the female temperature and acts as a temperature-sensitive regulator of STAT3 activation.
222 5 degrees C) intensity heat waves during key temperature-sensitive reproductive stages (R1, flowering
223 ate an immune signaling cascade that induces temperature-sensitive responses in addition to defects i
226 ationale for understanding the phenotypes of temperature-sensitive Sgt1 mutants and for linking Skp1-
228 o alpine areas should not be based solely on temperature-sensitive, site-specific upper-treeline stud
229 emperature window, which correlates with the temperature-sensitive size transition of the molecular a
230 rate that the phosphoswitch is intrinsically temperature sensitive, slowing down PER2 degradation as
235 have implications for the interpretation of temperature-sensitive, speleothem climate proxies such a
236 Accordingly, we find that previously known temperature-sensitive splicing mutants become lethal in
237 as found to be constitutively induced in two temperature-sensitive sss1 mutants (sss1(ts) ) that are
238 y, and demonstrates the need to identify the temperature-sensitive stages in predator-prey phenology
241 DX3X complements the growth defect in a ded1 temperature-sensitive strain of Schizosaccharomyces pomb
242 Starting with a conditional strain (i.e., a temperature-sensitive strain), we describe how to effici
243 tability, did not complement the growth of a temperature-sensitive strain, and had weakened dimerizat
244 clamp loader, complemented cell growth of a temperature-sensitive strain, and were successfully load
246 AF-C phosphorylation from wild-type and CKII temperature-sensitive strains (cka1Delta cka2-8) showed
247 folding-unfolding reaction of a specialized temperature-sensitive structure is coupled to TRPM8 gati
250 ze the conserved GII.4 blockade epitope were temperature sensitive, suggesting that particle conforma
252 nt temperature window which coincides with a temperature-sensitive switch in seed dormancy state.
253 d-site mutation that enhances lethality of a temperature sensitive tbx-2 mutant and show that this mu
255 ge upstream of the second AAA+ domain in the temperature sensitive TgNoAP1 allele leads to conditiona
256 ur models reveal that activation is far more temperature sensitive than inactivation, and we observe
257 ing flat watersheds was up to six times more temperature sensitive than streams draining steeper wate
258 d that the rate of dissociation was far more temperature-sensitive than the rates of both association
259 ral of these TRP channels on macrophages are temperature sensitive, they may comprise the link for hy
260 monstrate that human alpha2C-AR has a unique temperature-sensitive traffic pattern within the G prote
263 ilic supramolecular assemblies with a unique temperature-sensitive transition have been investigated.
264 e systems are known to exhibit a macroscopic temperature-sensitive transition, where the assembly pha
265 dence of the coupling between gating and the temperature-sensitive transitions, as well as the DeltaH
266 evere neurodevelopmental disorder defined by temperature-sensitive, treatment-resistant epilepsy-and
268 tivity to drive channel activation, allowing temperature-sensitive TRP channels to function as polymo
270 tates are derived from a human virus that is temperature sensitive (ts), characterized by restricted
272 ive attenuated influenza vaccines (LAIVs) on temperature-sensitive (ts) backbones derived from animal
273 ising live-attenuated vaccine candidate is a temperature-sensitive (ts) cDNA-derived virus named rA2c
274 and yielded variants with wild-type (wt) or temperature-sensitive (ts) growth phenotypes or had a le
281 have shown previously that incorporation of temperature-sensitive (ts) mutations into the PB1 and PB
282 ng the H3N2 NS1-V194I protein demonstrated a temperature-sensitive (ts) phenotype, providing a most l
283 hal mutants, bearing cold-sensitive (cs) and temperature-sensitive (ts) point mutations, were more am
284 e previously showed that introduction of the temperature-sensitive (ts) residue signature of the AA/6
285 n Mediator integrity is compromised in med17 temperature-sensitive (ts) yeast, demonstrating the modu
287 ver, our data uncover the molecular basis of temperature-sensitive UNC-45 mutations underlying one of
289 Alternatives to the widely used but highly temperature-sensitive uzu1.a allele of HvBRI1 represent
291 e results were validated using a yeast trs23 temperature sensitive variant that exhibits constitutive
293 nents and the rationale behind the design of temperature-sensitive vesicle systems, as well as the cr