ライフサイエンスコーパス: tenascin

1 ressed the extracellular marker, cytotactin (tenascin).

2 th localized expression of both versican and tenascin.

3 nd third strand in the beta-sandwich protein tenascin.

4 ing and promotes expression of scleraxis and tenascin.

5 third fibronectin type III domain from human tenascin.

6 third fibronectin type III domain from human tenascin.

7 nchymal condensation genes and deposition of tenascin.

8 Mutants of the tenascin 8-mer construct exhibit the same change in stab

9 onally, cell survival assays determined that tenascin and L1 Ab-treated cell suspensions yielded more

10 th myofibroblast formation and deposition of tenascin and procollagen I.

11 active for the extracellular matrix molecule tenascin and that treatment with the ototoxic antibiotic

12 ns known to be involved in adhesion, such as tenascins and integrins.

13 yaluronic acid and glycoproteins such as the tenascins and link proteins to form the matrix scaffold.

14 lectin domain that mediate interactions with tenascins and other extracellular-matrix proteins.

15 he extracellular matrix molecule tenascin-C (tenascin) and an antibody (Ab) to the cell adhesion mole

16 levels of extracellular matrix (versican and tenascin) and chemokine (BDFN, CCL5, CXCL5, and CXCL16)

17 llular matrix proteins, including collagens, tenascin, and fibronectin.

18 al changes in the expression of fibronectin, tenascin, and laminin.

19 f extracellular matrix proteins: collagen I, tenascin, and periostin.

20 LAST ACTIVATING PROTEIN, COLLAGEN 1 TYPE A1, TENASCIN, and SOD3 expression in PTC MSCs compared to Th

21 that of its modulators pleiotrophin, NrCAM, tenascin, and the chondroitin sulfate proteoglycans, sug

22 In contrast, the production of decorin, tenascins, and fibromodulin markedly increased.

23 In vitro, both tenascin- and L1 Ab-treated cultures doubled the number

24 In contrast to the culture results, tenascin- and L1 Ab-treated mesencephalic grafts did not

25 Fibronectin and tenascin are large extracellular matrix proteins that in

26 conditions (3 microl of 3,000 cells/microl), tenascin augmented grafted THir neuron survival.

27 Cells that express tenascin begin to recover after about 2 weeks and are th

28 C promotes growth of axons if they express a tenascin-binding integrin, particularly alpha9beta1.

29 termined the expression of Ets-1, MMP-9, and tenascin by bronchial fibroblasts activated ex vivo.

30 As branches extend, tenascin C (TNC) accumulates in the mesenchyme several c

31 ed the expression of the profibrotic factors tenascin C (TNC) and connective tissue growth factor (CT

32 umor-associated extracellular matrix protein tenascin C (TNC) in xenografts, which was further examin

33 Tenascin C (TNC) is a matricellular glycoprotein whose e

34 catenin signaling led to marked induction of tenascin C (TNC), an established promoter of cancer meta

35 of multiple metastasis effectors, including Tenascin C (Tnc), Jagged1 (Jag1), and Epiregulin (Ereg).

36 ranscriptional regulation of the ECM protein tenascin C (Tnc), which was necessary and sufficient for

37 ), mapped within the gene coding sequence of Tenascin C (TNC).

38 metastasis-initiating ability by expressing tenascin C (TNC).

39 ctive tissue growth factor (Ctgf, P = 0.04), tenascin C (Tnc, P = 0.035), Collagen Ialpha1 (Col1a1, P

40 CD44, tenascin C and fibrillin-1 mRNA levels were reduced by 4

41 s such as SPARC, thrombospondin 1 and 2, and tenascin C and X subserve important functions in extrace

42 ation of thick fibronectin fibrils, to which tenascin C colocalized.

43 We conclude that tenascin C contributes to the generation of a stem cell

44 ltured on osteo-mimetic surfaces coated with tenascin C exhibited enhanced adhesion and colony format

45 Here, we report that tenascin C is expressed in the bone endosteum and is ass

46 Tenascin C is highly expressed in the SVZ, and transgeni

47 21-associated differentiation in wdSCCs; yet tenascin C retention in connective tissue extracellular

48 ssed in the SVZ, and transgenic mice lacking tenascin C show delayed acquisition of the EGF receptor.

49 ha-smooth muscle actin were reduced, whereas tenascin C was increased, suggesting that P15-1 promoted

50 remodeling such as MMP-9, procollagen-3, and tenascin C were observed in all acute eczematous lesions

51 JNK activation, leading to the production of tenascin C, a pro-invasive matricellular protein.

52 and media-lumen ratio and overexpression of tenascin C, an extracellular matrix glycoprotein that co

53 Bone matrix markers (biglycan, COL1A1, tenascin C, and fibronectin) and low-density lipoprotein

54 ges in netrin 4, fibroblast growth factor 2, tenascin C, collagen 1, meprin 1-alpha, and meprin 1-bet

55 Total levels of tenascin C, collagen type XII, and CD44 mRNA were increa

56 nipin reduced the levels of collagen type I, tenascin C, elastin and versican.

57 ey cellular regulators, such as EGFR, HSP70, Tenascin C, Frizzled-5, Patched-1, and Delta-like 1.

58 SCCs exhibited increased NF-kappaB and novel tenascin C, indicative of elevated rigidity; yet despite

59 including VEGF, IL-6, VEGF-C, HB-EGF, CTGF, tenascin C, integrin alpha5, and Eph receptor A2.

60 of proangiogenic genes, such as osteopontin, tenascin C, KGF, angiopoietin, HIF-1alpha, and PDGFRbeta

61 , vimentin, discoidin domain receptor 2, and tenascin C, markers of fibroblasts and components of the

62 he desmoplastic extracellular matrix protein tenascin C, suppressing tumor outgrowth, and improving h

63 llular deposits of eosinophil peroxidase and tenascin C, the effects not seen with placebo.

64 taining the fibronectin type III domain D of tenascin C, the long NC3 isoform of collagen type XII, t

65 For cyclinD1, fibulin 2, tenascin C, TIMP1, and aquaporin-4, correlations were si

66 ulation of the extracellular matrix protein, tenascin C, which affords a scaffold for VSMC migration.

67 p21 loss, elevated NF-kappaB expression and tenascin C-associated rigidity, with p-Mypt1 inactivatio

68 Tenascin C-deficient mice also have altered numbers of C

69 a correlation of IL-17+ T cell numbers with tenascin C-expressing cells and MMP-9+ eosinophils was a

70 ctor SOX4 and extracellular matrix component tenascin C.

71 ascular endothelial growth factor (VEGF) and tenascin C.

72 (+)) preceded K14.ROCK(er)-mediated (p-Mypt1/tenascin C/rigidity) malignant conversion.

73 top 10 results (collagen, type III, alpha-1; tenascin C; collagen, type VI, alpha-3; thrombospondin 2

74 Tenascin-C (encoded by Tnc) is an extracellular matrix g

75 e utilized the extracellular matrix molecule tenascin-C (tenascin) and an antibody (Ab) to the cell a

76 Tenascin-C (TN) is an extracellular matrix protein that

77 Enhanced expression of tenascin-C (TN-C) at the invasive edges of glioblastoma

78 Tenascin-C (TN-C) is an extracellular matrix (ECM) prote

79 Tenascin-C (TN-C) is expressed in embryogenesis, tissue

80 To address this question, we focused on tenascin-C (TN-C), a stromal extracellular matrix glycop

81 icipates in network formation, we focused on tenascin-C (TN-C), an extracellular matrix (ECM) protein

82 PDGF-BB also stimulates the expression of tenascin-C (TN-C), an extracellular matrix glycoprotein

83 vation of FAK and cellular interactions with tenascin-C (TN-C).

84 tified the extracellular matrix glycoprotein tenascin-C (TNC) as an important regulator of ENCC devel

85 pattern of the extracellular matrix molecule tenascin-C (Tnc) in the developing mouse olfactory bulb

86 Tenascin-C (TNC) is a highly conserved matricellular pro

87 Tenascin-C (TNC) is a mechano-regulated, morphogenic, ex

88 Tenascin-C (Tnc) is an extracellular matrix protein (ECM

89 Tenascin-C (TNC) is highly expressed in melanoma; howeve

90 r mPIN used the extracellular matrix protein Tenascin-C (TNC) to inhibit T-cell receptor-dependent T-

91 Tenascin-C (TNC) was identified as one of the key ECM ma

92 Here we provide evidence that tenascin-C (TNC), an extracellular matrix protein promin

93 Tenascin-C (TnC), an extracellular matrix protein, is tr

94 ting of ECM protein cargo subsets, including Tenascin-C (TnC), and for fibroblast-derived exosomes to

95 ral S100 proteins, including Fibronectin and Tenascin-C (Tnc), in primary lung tumors and associated

96 Tenascin-C (TNC), overexpressed in invasive growths, has

97 or alpha-smooth muscle actin (alpha-SMA) and tenascin-C (TNC).

98 y HIV-1-neutralizing protein in breast milk, Tenascin-C (TNC).

99 peptide that interacts with the C-isoform of Tenascin-C (TNC-C) upregulated in malignant tissues.

100 ctin (fnFN10) and the 3rd FN-III domain from tenascin-C (tnFN3) have 27% sequence identity and the sa

101 Syndecan-4 is also required for tenascin-C action.

102 Inhibition of syndecan-4 function suppresses tenascin-C activity and overexpression of syndecan-4 cir

103 stains in the rodent heart demonstrated that tenascin-C also colocalizes with EPCs homing to sites of

104 ie, production of collagen, fibronectin, and tenascin-C and accumulation of myofibroblasts).

105 ronment consisting of the highly upregulated tenascin-C and chondroitin sulfate proteoglycans (CSPGs)

106 ith matrices representative of transitional (tenascin-C and fibronectin) and differentiated environme

107 nts of this dynamic matrix, hyaluronic acid, tenascin-C and fibronectin, differentially direct cellul

108 ograft model of advanced human osteosarcoma, tenascin-C and its receptor integrin alpha9beta1 were de

109 The functional importance of stromal Tenascin-C and S100A4(+) fibroblast-derived VEGF-A in me

110 the expression of matrix metalloproteinases, tenascin-C and Sox9 and decreases the expression of scle

111 In this way, tenascin-C and syndecan-4 work together to control fibro

112 d in the developing brain: the glycoproteins tenascin-C and tenascin-R and the chondroitin sulfate pr

113 ta1- and FGF-2-induced de novo expression of tenascin-C and the downregulation of alpha3(IV) collagen

114 alpha7beta1 integrin mediates a response to tenascin-C and the first to demonstrate a functional rol

115 M molecules and growth factors, particularly Tenascin-C and VEGF-A.

116 Levels of tenascin-C are elevated in SSc skin biopsy samples, and

117 Similarly, cellular fibronectin isoforms and tenascin-C are present in the tumor microenvironment.

118 s performed and led to the identification of tenascin-C as a candidate protein.

119 valuate the contribution of the glycoprotein tenascin-c as a key mediator of smooth muscle cell growt

120 Together, our data highlight the role of tenascin-C as a microenvironmental regulator of cardiac

121 Thus, we have identified tenascin-C as a novel endogenous activator of TLR4-media

122 These results identify tenascin-C as an endogenous danger signal that is upregu

123 Our study revealed midkine, CYR61, and tenascin-C as endogenous substrates for KLK7.

124 ype mice or mice with a targeted deletion of tenascin-C by assessing cell maturation, cytokine synthe

125 PGE(2) but more PGI(2) and expressed reduced tenascin-C compared with wild-type cells.

126 The region of tenascin-C containing only alternately spliced fibronect

127 Tenascin-C deficiency resulted in minor structural diffe

128 -C, and osteopontin, revealed that MMP-9 and tenascin-C demonstrated reduced expression both in vitro

129 C-AR modified cells aggregated to cells in a tenascin-C expressing stem cell niche model better than

130 PGE(2) and augmentation of PGI(2) attenuate tenascin-C expression and vascular smooth muscle cell pr

131 showed both retention of alpha9 integrin and tenascin-C expression at the anterior stromal-epithelial

132 Among these cells, tenascin-C expression is most highly induced in activate

133 nregulated both TGF-beta1- and FGF-2-induced tenascin-C expression, ROCK inhibition was found to down

134 after vascular injury, in part by regulating tenascin-C expression.

135 pathologic remodeling with aberrant Prx1 and Tenascin-C expression.

136 eased proliferating cell nuclear antigen and tenascin-C expression.

137 To determine the importance of tenascin-C in cardiac neovascularization, we used an est

138 diated induction of procollagen type III and tenascin-C in isolated cardiac fibroblasts was dependent

139 cts, interstitial deposition of collagen and tenascin-C in the remodeling myocardium was markedly red

140 ults illuminate how tumor cell deposition of tenascin-C in the tumor microenvironment promotes invasi

141 te how the extracellular matrix glycoprotein tenascin-C in the tumor microenvironment promotes invasi

142 aim of this study was to examine the role of tenascin-C in this cell type.

143 n in vivo in mice, and addition of exogenous tenascin-C induces cytokine synthesis in explant culture

144 ia of individuals with rheumatoid arthritis, tenascin-C induces synthesis of proinflammatory cytokine

145 Functionally, tenascin-C inhibits cardiac endothelial cell spreading a

146 Tenascin-C is a large extracellular matrix glycoprotein

147 Tenascin-C is an arthritogenic extracellular matrix glyc

148 Tenascin-C is an extracellular matrix molecule that driv

149 Tenascin-C is an extracellular matrix protein that regul

150 We show that tenascin-C is anti-adhesive for retinal pigmented epithe

151 The inhibitory effect of tenascin-C is circumvented by downstream activation of R

152 This demonstrates for the first time that tenascin-C is essential for postnatal cardiac angiogenic

153 Tenascin-C is expressed transiently during wound repair

154 These data demonstrate that tenascin-C is important in DC-mediated polarization of T

155 position of the extracellular matrix protein tenascin-C is part of the reactive stroma response, whic

156 Here we show that tenascin-C is produced by type-B cells and forms a layer

157 Tenascin-C levels and tumor uptake were studied in a var

158 Cells surrounded by a fibrin-FN+tenascin-C matrix are unable to induce matrix contractio

159 to facilitate colonization, whereas stromal Tenascin-C may provide protection from apoptosis.

160 SMA, vimentin, and tenascin-c mRNAs were decreased by 60%, 40%, and 49%, re

161 A in metastasis was established by examining Tenascin-C null mice and transgenic mice expressing Cre

162 association of the alpha7beta1 integrin with tenascin-C peptides containing the VFDNFVLK sequence but

163 utonomous signaling mechanism explaining how tenascin-C promotes cancer cell migration in the tumor m

164 Tenascin-C promotes growth of axons if they express a te

165 Intra-articular injection of tenascin-C promotes joint inflammation in vivo in mice,

166 Analysis of human coronary thrombi revealed tenascin-C protein expression colocalized with the endot

167 Cells on fibrin-FN+tenascin-C redistribute their actin to the cell cortex,

168 f the provisional matrix, we have found that tenascin-C regulates cell responses to a fibrin-FN matri

169 se of MMPs was accompanied by an increase in tenascin-C release.

170 aling by competitive binding of fibulin-1 or tenascin-C represents a shared mechanism of adhesion mod

171 Mice lacking tenascin-C show attenuation of skin and lung fibrosis, a

172 Here we show that mice that do not express tenascin-C show rapid resolution of acute joint inflamma

173 we show that the regenerative ECM component tenascin-C significantly increases newt cardiomyocyte ce

174 Exogenous tenascin-C stimulates collagen gene expression and myofi

175 Here we map three sites within tenascin-C that directly and cooperatively interact with

176 EDGIHELFP(48)) resembles the sequence within tenascin-C to which the integrin alpha(9)beta(1) binds.

177 sis of PAH such as serotonin transporter and tenascin-C was elevated in distal arteries and had a hig

178 ar degeneration-affected Bruch's membrane is tenascin-C which we confirm is present at high levels in

179 ne signature identified five common targets: tenascin-C(TNC), matrix metalloprotease-2, collagen-6-A1

180 s for cell adhesion/motility (syndecan-4 and tenascin-C) and hyaluronan (HA) signaling.

181 ciated KLKs), whereas others (e.g. CYR61 and tenascin-C) could be digested by several KLKs.

182 nents (fibrillar type I and III collagen and tenascin-C) had no effect.

183 Tenascin-C, a matrix protein induced upon tissue damage

184 Induction of tenascin-C, a proproliferative and promigratory extracel

185 Tenascin-C, an extracellular matrix protein involved in

186 hed with vascular endothelial growth factor, tenascin-C, and activated matrix metalloproteinase-9, fa

187 transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls muscle cell behavio

188 We could validate phosphacan, tenascin-C, and L1-CAM as major LeX carrier proteins pre

189 n, matrix metalloproteinases (MMPs) 2 and 9, tenascin-C, and osteopontin, revealed that MMP-9 and ten

190 lly expresses neural cell adhesion molecule, tenascin-C, and other molecules.

191 several MMPs, TGF-beta signaling molecules, Tenascin-C, and VEGF-A, while pro-fibrotic molecules, in

192 at contain extra domains A and B, as well as tenascin-C, are present for several days in the wound ex

193 adhesion modulatory proteins, fibulin-1 and tenascin-C, both of which bind to the C-terminal heparin

194 infant but not the adult DM was positive for tenascin-C, fibrillin-1, SPARC, and laminin-332.

195 Here, we report that, like tenascin-C, fibulin-1 inhibits fibroblast spreading and

196 Dendritic cells that did not express tenascin-C, however, produced lower levels of inflammato

197 show dynamic spatial and temporal changes in tenascin-C, hyaluronic acid, and fibronectin ECM distrib

198 ed by expressing an integrin that recognizes tenascin-C, one of the components of glial scar tissue,

199 as occurs in the presence of the ECM protein tenascin-C, promotes a motile phenotype; FAK and Rho sig

200 nD to an eight amino acid sequence unique to tenascin-C, VFDNFVLK, and showed that the amino acids FD

201 Fibroblast response to fibulin-1, similar to tenascin-C, was dependent on expression of the heparan s

202 aptamer to the extracellular matrix protein tenascin-C, was prepared in fluorescent and radiolabeled

203 pha-smooth muscle actin (SMA), vimentin, and tenascin-c, were measured in archived human HCC tissues

204 Calcific leaflets also exhibit tenascin-C, which may facilitate inflammatory cell migra

205 model and showed that unlike wild-type mice, tenascin-C-/- mice fail to vascularize cardiac allograft

206 Tenascin-C-AR modified cells aggregated to cells in a te

207 stem cell (HSC) mimics were modified with a tenascin-C-AR to improve the homing of HSC after an auto

208 ted epithelial cells with alpha9 integrin, a tenascin-C-binding integrin, led to a large increase in

209 Using live-cell imaging, we found softer tenascin-C-coated substrates significantly enhanced migr

210 cells preferentially migrated and colonized tenascin-C-coated trabecular bone xenografts in a novel

211 Moreover, tenascin-C-null mice displayed ablated levels of interle

212 Dendritic cells derived from tenascin-C-null mice exhibited no defects in maturation;

213 dorsal root ganglia regenerated through the tenascin-C-rich dorsal root entry zone into the dorsal c

214 levels under the control of the promoter for tenascin-C.

215 egulation of anti-adhesive molecules such as tenascin-C.

216 pha9beta1-mediated adhesion and migration on tenascin-C.

217 eractions between the aggrecan G3 domain and tenascin-C.

218 ggrecan as well as articular markers such as tenascin-C.

219 ed the presence of the target protein, human tenascin-C.

220 rite outgrowth by itself and also as part of tenascin-C.

221 ion of syndecan-4 circumvents the effects of tenascin-C.

222 omains A and B, and the FnIII repeats within tenascin-C.

223 on of proliferating cell nuclear antigen and tenascin-C.

224 ased EMT protein markers, SMA, vimentin, and tenascin-c.

225 f age, there were fewer condylar superficial tenascin-C/Col1-positive cells and more numerous apoptot

226 co-localizing with the fibrillar fibronectin/tenascin-C/periostin structures that characteristically

227 of membrane and secreted proteins, including Tenascins, Cathepsin-B precursor, cystatin, and numerous

228 metry, toxicity, and response of (131)I anti-tenascin chimeric 81C6 for the treatment of lymphoma.

229 ce in the LIF-null animals including desmin, tenascin, Cox-2, bone morphogenetic protein (BMP)-2 and

230 on allergen-induced eosinophil accumulation, tenascin deposition (as a marker of repair and remodelli

231 cosal type I and III collagen expression and tenascin deposition was also observed in swimmers than i

232 including fibronectin, laminin, vitronectin, tenascin, elastin, fibrillin-1, microfibril-associated g

233 including fibronectin, laminin, vitronectin, tenascin, elastin, fibrillin-1, microfibril-associated g

234 monstrate that TNF-alpha increases MMP-9 and tenascin expression in bronchial fibroblasts via the tra

235 nd that it contributed to enhanced MMP-9 and tenascin expression.

236 TGF-beta1 and IL-13 also induced tenascin expression.

237 Tenascin-R (TN-R) is a member of the tenascin family of multidomain matrix glycoproteins that

238 We found that tenascin fragments that contain type III modules 3-5 bin

239 ) and TNfn3 (the third fnIII domain of human tenascin), have essentially the same backbone structure,

240 48 h skin biopsies as well as the numbers of tenascin immunoreactive cells at 48 h.

241 results in a nearly complete elimination of tenascin immunoreactivity.

242 decorin, versican, fibronectin, laminin and tenascin in ASM was quantified as fractional area and me

243 Fibronectin is a covalent dimer and tenascin is a hexamer.

244 Tenascin is an extracellular matrix glycoprotein that is

245 lphaPS2) integrin receptor and transmembrane tenascin ligand are both suppressively downregulated in

246 In conclusion, pretreatment with tenascin may prove beneficial to prevent anoikis in dilu

247 er, DLX regulates the expression of NCAM and tenascin, molecules that are important for feather bud i

248 ein, which preceded an increase in MMP-9 and tenascin mRNA.

249 ith direct injections of (131)I-labeled anti-tenascin murine 81C6 monoclonal antibody (mAb) into surg

250 matricellular proteins, such as osteopontin, tenascin or secreted protein acidic and rich in cysteine

251 s containing the complete 20-mer or a 12-mer tenascin peptide partially blocked phage binding to the

252 gic reaction and (b) shows that decreases in tenascin positive cells at 48 h correlates with reductio

253 ast to tendon-associated genes scleraxis and tenascin, present in the chordae tendineae.

254 Both MMP-9 and tenascin promoters contain an Ets binding site, suggesti

255 duced Ets-1, MMP-9, and, to a lesser extent, tenascin protein expression or activity.

256 ecreted protein acidic and rich in cysteine, tenascins), proteoglycans (eg, versican, syndecans, bigl

257 Tenascin-R (TN-R) is a member of the tenascin family of

258 f chondroitin sulfate proteoglycans (CSPGs), tenascin-R (TN-R), hyaluronan (HA), and link proteins, s

259 e of the purified proteins was identified as tenascin-R (TNR) by mass spectrometric analysis.

260 w that the extracellular matrix glycoprotein tenascin-R (TNR) is produced in the granule cell layer o

261 ping brain: the glycoproteins tenascin-C and tenascin-R and the chondroitin sulfate proteoglycans bre

262 We focused on aggrecan, brevican, and tenascin-R as they are especially expressed in the matur

263 We have determined that tenascin-R associated with Purkinje cell bodies and thei

264 Versican and tenascin-R colocalized in OLCs, and coimmunoprecipitatio

265 with beta1,4-linked GalNAc-4-SO(4), whereas tenascin-R in other regions of the cerebellum does not b

266 The cellular adhesion molecule tenascin-R is a multifunctional extracellular matrix com

267 the PNN structural abnormalities observed in tenascin-R knockout brains.

268 sed the effect of aggrecan, brevican, and/or tenascin-R on neurite outgrowth in vitro.

269 abundance of ECM proteins brevican (BCN) and tenascin-R over the course of acquisition learning, cons

270 rotein expression of aggrecan, brevican, and tenascin-R throughout the rat brain utilizing immunohist

271 eceptors -1, -4, and -5, homer-1 and -2, and tenascin-R.

272 d alpha10 (collagen receptors) and alpha9 (a tenascin receptor).

273 The expression of MMP-9 and tenascin reflects disease activity in asthma and airway

274 etinal pigment epithelial cells to adhere to tenascin-rich wet age-related macular degeneration-affec

275 ctin type III domains from the human form of tenascin that exhibits approximately 1 kcal mol(-1) incr

276 perfamily, the third fnIII domain from human tenascin (TNfn3) and the tenth fnIII domain from human f

277 l in cross-linking aggrecan, hyaluronan, and tenascin to form extended protein networks found in tiss

278 between various fragments of fibronectin and tenascin to further characterize and localize the bindin

279 The site on tenascin to which fibronectin binds has been localized t

280 ing Abs to TGF-beta as well as production of tenascin transcripts and protein product.

281 e if several potential ligands (fibronectin, tenascin, vitronectin, and osteopontin) were expressed d

282 thickness (CCT) of wild-type, TNC(-/-), and tenascin X (TNX(-/-)) knockout mice were measured.

283 Tenascin X (TNX) functions in the extracellular matrix o

284 Histocompatibility Complex (MHC) including: tenascin X (TNX); cytochrome P450, subfamily XXIA, polyp

285 like (FBG) domain of the matrix glycoprotein tenascin-X (TNX) interacts physically with the small lat

286 Tenascin-X (TNX) is a glycoprotein that regulates tissue

287 uctural level, detection of collagen XII and tenascin-X by immunogold labeling confirmed this finding

288 Tenascin-X deficiency in humans is associated with Ehler

289 Tenascin-X is a large extracellular matrix protein expre

290 Tenascin-X is a large extracellular matrix protein of un

291 collagen-modifying enzyme, we suggested that tenascin-X might regulate collagen synthesis or depositi

292 Collagen type V, decorin, fibromodulin, and tenascin-X proteins were unaffected by the cross-link in

293 gen XII was found for the avian homologue of tenascin-X that in humans is linked to Ehlers-Danlos dis

294 and other extracellular proteins (periostin, tenascin-X).

295 gment with sequence identity to a peptide in tenascin-X, an extracellular matrix protein.

296 glycoprotein, serum amyloid P-component, and tenascin-X, were selected as promising examples of the u

297 omic symptoms and is linked to a mutation in tenascin-X.

298 ts of alpha1(IV) and alpha1(V) collagens and tenascin-X] and three peptides that increased (fragments

299 ygous mutation (T3257I) in the gene encoding tenascin XB (TNXB in 6p21.3).

300 polymorphisms on chromosome 6p21.3 at TNXB (tenascin XB)-FKBPL (FK506 binding protein like) [rs12153