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2 associated with systemic inflammation often termed a "cytokine storm." Because interleukin-1 (IL-1)
5 fluorescent-protein-tagged actin nanobodies, termed 'actin chromobodies' (ACs), targeted to organelle
7 pisodes of acute worsening of their disease, termed acute exacerbation of IPF, which may be caused by
8 al Ad26 vector-based vaccine for SARS-CoV-2, termed Ad26.COV2.S, is currently being evaluated in clin
10 nergy expenditure through heat generation is termed adaptive thermogenesis, a process carried out by
11 of aging patterns in different individuals, termed 'ageotypes', on the basis of the types of molecul
12 rt aggregation motif in the FVIII A1 domain (termed Aggron) is necessary and sufficient to seed beta-
15 homolog to murine CXCR5IFN-gammaCD8 T cells (termed antibody-suppressor CD8 T cells) and that the qua
16 sign of a highly stable fluorogenic peptide (termed Apo-15) that selectively stains apoptotic cells i
17 robiome in two independent transgenic lines, termed APP(SWE)/PS1(DeltaE9) and APPPS1-21, leads to a r
18 ids (PE1-9) with two types of architectures, termed as "brush" and "block," were built from positivel
19 olymyxa strain E681, its phenotypic variant, termed as F-type, fails to form spores, does not confer
26 esses can likewise produce precise patterns, termed attractor patterns, that reform their precise sha
27 subsets in both mice and non-human primates, termed autofluorescence-positive (AF(+)) and negative (A
28 ral nervous system (CNS) autoimmune diseases termed autoimmune encephalitides (AE), which are charact
30 t, selection of awns with minimal extension, termed awnletted, has occurred during domestication by w
31 d that surgery for the treatment of obesity (termed bariatric or metabolic surgery) reduces all-cause
33 n expressing a new type of Split-GFP that we termed Bi-Genomic Mitochondrial-Split-GFP (BiG Mito-Spli
40 PR-Cas13a-based antibacterial nucleocapsids, termed CapsidCas13a(s), capable of sequence-specific kil
41 and micron dimensioned morphology of carbon, termed Carbon Nano-Scaffold (CNS) with wide a range of h
42 dly distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti-phage si
43 difficile toxin has an enzymatic component, termed CDTa, and a pore-forming or delivery subunit term
50 coronary heart disease(5)-this phenomenon is termed clonal haematopoiesis of indeterminate potential
51 somatic mutations in the peripheral blood is termed clonal hematopoiesis of indeterminate potential (
54 lly by imine linkages to produce 1D ribbons, termed COF-76, bearing free amines, which are then used
55 als will develop symptomatic diverticulosis, termed colonic diverticular disease (also known as diver
56 ideration to how these skin residents, often termed "commensals" can cause disorder, damage, and prom
58 ear dynamical system for microbial dynamics, termed "compositional" Lotka-Volterra (cLV), unifying ap
60 ditionally been divided into 2 major subsets termed conventional monocytes and patrolling monocytes (
61 ls, and demonstrate that a class of origins, termed core origins, is shared by different cell types a
62 causes a pathogenic condition that has been termed coronavirus disease 2019 (COVID-19) and has reach
67 e nicotine acetylcholine receptors (nAChRs), termed (D)CDX, enables drug delivery to the brain when i
71 a mitochondrial-associated gene in a mouse (termed decrepit) that results in adult-onset neurodegene
75 he correction to a standard DFT calculation, termed Delta-DFT ) significantly reduces the amount of t
77 nificant research attention this phenomenon, termed diabetic cardiomyopathy, has received over severa
79 indoline, through syntheses of compounds now termed "dihydropsychotriadine" and "psychotriadine".
80 ed at the distal prostate invagination tips (termed Dist-Luminal-C) exhibited greater capacity for or
81 theoretically proposed class of mechanisms, termed "distal pinning," achieves robustness by combinin
82 to the helical pilus rod through a mechanism termed donor strand complementation, in which the incomp
83 al forms through a poorly understood process termed dorsal collapse that involves attrition and remod
84 is approach to altering tumor blood flow was termed "dynamic control." Dynamic control of tumor vesse
85 l-defined T3SS but in addition a second T3SS termed E. coli T3SS 2 (ETT2) has been described in a num
87 f an impedance-based approach, which we have termed electrochemical phase interrogation, as a means o
89 derives from integrated retroviral elements, termed endogenous retroviruses (ERVs), that comprise ~8%
92 arious covalent modifications added to RNAs, termed epitranscriptomic modifications, can positively r
94 ctural characteristics of sEVs, collectively termed 'EV-nano-metrics' enhances the understanding of t
95 small extracellular vesicles (sEVs, formerly termed "exosomes") isolated at ~100 000g are known, a wi
97 er connects mitochondria beyond hyperfusion, termed extreme fusion, leading to bioenergetic deficits.
99 ght mass spectrometry (MALDI-TOF MS) plates, termed fast lipid analysis technique or FLAT, which faci
100 RA 3.0 using C/C++, and developed a toolbox, termed FastMM, to effectively conduct constraint-based m
103 The pathology of frontotemporal dementia, termed frontotemporal lobar degeneration (FTLD), is char
107 A recently identified SWI/SNF subcomplex termed GLTSCR1/1L-BAF (GBAF; or "noncanonical BAF", ncBA
108 ree-fatty acid receptor-4 (FFA4), previously termed GPR120, is a G protein-coupled receptor (GPCR) fo
112 The top-performing prediction model was termed "gSOS", and its utility in fracture risk screenin
113 led plasma-MS, we validated that this assay, termed here "manganese-extracting small molecule estimat
114 t that has a ubiquitous tissue distribution, termed here as CDC42u, specifically drives the formation
118 on of this gene causes a separate neuropathy termed hereditary neuropathy with liability to pressure
119 ease risk attributable to genetic variation, termed heritability, is high, with estimates from family
120 In this work, we present a facile method termed high-salt molecular rheotaxis (HiSMRT) to concent
121 stacquisition data reconstruction technique, termed "high resolution demultiplexing" (HRdm), to impro
122 tributed P. aeruginosa sequence types (STs), termed "high-risk clones." We noted that clonal complex
123 hydroxyanthranilic acid + anthranilic acid), termed HK ratio (HKr), was related to plasma PLP with st
124 ansplants (LDKTx) from HLA matched siblings (termed HLA-identical (HLA-ID)) to HLA non-ID to investig
125 he data presented here revealed low-density, termed hollow, nanoparticles (hNPs) load and release sig
127 stratification that focuses on peak breadth, termed hyperacetylated chromatin domains (HCDs), which c
129 ly symmetric, stable intercellular junctions termed immunological synapses which facilitate exchange
133 corresponding leucine-rich repeat receptor, termed INR, specific to select legume species and suffic
134 ically distinct infectious enveloped virions termed intracellular mature virions and extracellular vi
136 hese small-molecule inhibitors, collectively termed JAK inhibitors, are US Food and Drug Administrati
137 se cells, making them susceptible to killing-termed kick and kill regimens-have been explored as a st
138 ails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respec
139 lamina-a meshwork of intermediate filaments termed lamins-is primarily responsible for the mechanica
140 e GCs by evoking potent nondepressing EPSPs (termed large-amplitude, nondendrodendritic [LANDD] EPSPs
144 say, we demonstrate how these chimeric RTKs, termed light-controlled human insulin receptor (LihIR) a
146 Two glycine lipid classes were identified, termed lipid 567 and lipid 342, and these lipid classes
149 nto the memory phase and that these T cells (termed long-lived effector cells [LLEC]) display robust
150 pectively validate a machine-learning method termed 'lung cancer likelihood in plasma' (Lung-CLiP), w
151 study of a neutralizing monoclonal antibody termed mAb P-4G2, which neutralizes the zoonotic pathoge
153 d subretinal fibrosis; (2) an affected area, termed MacTel area, limited to a horizontal diameter not
154 repeat revascularization, stroke, or death (termed major cardiovascular and cerebrovascular events [
160 oduced by Meibomian glands (MG) in a process termed meibogenesis-plays a critical role in ocular surf
164 address this challenge, we present a method, termed metabolic activity phenotyping (MAP), to probe me
165 eferencing O(2)-specific micro-optrode (also termed micro-optode and optical fiber microsensor) is a
166 Here, we characterized three MIF orthologs (termed MIF/d-dopachrome tautomerase-like proteins or MDL
167 ial infection downregulated miR-148a-3p (now termed miR-148) in macrophages in an ESX-1-dependent man
168 e elimination of mitochondria via autophagy, termed mitophagy, is an evolutionarily conserved mechani
169 osis with at least equal mortality to LB was termed "mNIT." Existing NITs were then compared using bo
170 ariants associated with intermediate traits, termed molecular quantitative trait loci (molQTLs), can
171 nsitive fluorophores based on a BODIPY core, termed "molecular rotors", in combination with Fluoresce
172 d by previously-reported synthetic proteins, termed monobodies, that bind the GPR56 ECR in a domain-
173 ere, we develop synthetic antibody mimetics, termed monobodies, to interfere with STAT3 signaling.
174 ng immunoproliferative disorder that we have termed monoclonal gammopathy of macular significance.
175 reviously described mass spectrometry method termed monoclonal immunoglobulin rapid accurate mass mea
176 UV-crosslinking and profiled by proteomics (termed mRBPome capture), yielding a putative repertoire
177 ently, a severe and novel pediatric disorder termed multisystem inflammatory syndrome in children (MI
178 a surge in the life-threatening illness now termed 'multisystem inflammatory syndrome in children' (
180 ng a microfluidic sample preparation system, termed nanoPOTS (nanodroplet processing in one pot for t
181 formulated a bi-level optimization framework termed NECom for which any feasible solutions are Nash e
186 ternalization of the central nervous system, termed neurulation in vertebrates, is a critical step in
187 acterial type III secretion system effector, termed NleD, a metalloprotease that inactivates MAPKs by
188 nized non-mobile colistin resistance enzyme, termed NMCR-2, originating from the plant pathogen Kosak
190 ogression of an RNA quality control pathway, termed nonsense-mediated mRNA decay (NMD), by phosphoryl
194 ved sEVs and medium size EVs (mEVs, commonly termed "oncosomes") preisolated by differential centrifu
195 l-permeable photoswitchable small molecules, termed optojasps, are introduced to optically control th
199 ented here is a fragment-screening platform, termed PhABits (PhotoAffinity Bits), which utilizes a li
200 ve self-assembly of the Mn(4)CaO(5) cluster, termed photoactivation, utilizes the same highly oxidizi
201 k, we propose a novel deep learning approach termed pixel-wise deep learning (Pixel-DL) that first em
203 cameric peptide antagonists of MDM2 and MDMX termed PMIs, one of which, TSFAEYWALLSP, bound to MDM2 a
206 test for this form of PRA in the breed, here termed PRA4 to distinguish it from other forms of PRA de
208 d a subset of open chromatin regions (OCRs), termed predicted regulatory elements (pREs), that are li
210 ng short pieces of the invading nucleic acid termed prespacers and inserting them into their CRISPR a
213 o inducing a type of inflammatory cell death termed "pyroptosis." Leukotriene B(4) (LTB(4)) is a lipi
215 subset 2 LC carries a single-point mutation, termed R110, at the junction between the variable and co
216 roduction of Ang II relative to Ang (1-7) is termed RAS dysregulation and leads to cellular signals,
218 of robust recurrent genomic break clusters, termed RDCs, in cultured primary mouse neural stem and p
219 data obtained during routine clinical care, termed "real-world" data, will be accumulated across hea
220 ased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappaB ligan
221 ttenuating cell-surface receptor signalling, termed receptor inhibition by phosphatase recruitment (R
222 We present a feature representation approach termed REFINED (REpresentation of Features as Images wit
223 n some patients with advanced heart failure (termed responders [R]) following left ventricular assist
227 ls that capture sample-sample relationships (termed SampleLASSO), built on-the-fly for each new targe
228 the control of a novel supergene haplotype (termed Sb), which evolved by sequential incorporation of
232 that selectively kill senescent cells (SCs), termed senolytics, have the potential to prevent and tre
233 ified a novel, to our knowledge, GFP variant termed short-lifetime monomeric GFP with the so-far shor
234 ring-dubbed happy hypoxia but more precisely termed silent hypoxemia-is especially bewildering to phy
235 tigated the ecological parameter reductions (termed "similitudes") and characteristic patterns of the
236 organs, with loss of microvascular function, termed small vessel disease (SVD) underlying different p
237 omain of SNX5 or SNX6 and a bipartite motif, termed SNX-BAR-binding motif (SBM), in the cargoes.
240 d promote translation of two protein halves, termed Split-ORFs, from the bicistronic SRSF7-PCE transc
241 on-nucleotide, small-molecule STING agonist, termed SR-717, that demonstrates broad interspecies and
242 Here, we developed star-shaped particles, termed STAR particles, to dramatically increase skin per
245 deposit, reticular pseudodrusen (RPD) (also termed subretinal drusenoid deposits, SDD), which are lo
247 found two populations of layer 2-3 neurons, termed success- and failure-related neurons, that develo
248 increased levels of chromatin interactivity-termed super-interactive promoters-are enriched for line
249 odifications, led us to a verifiable concept termed "superchanneling." In superchanneling, the synthe
251 to increasing sympathetic vasomotor outflow, termed sympathetic neurovascular transduction (sNVT), ac
253 are uniformly multiplied by a single factor, termed "synaptic scaling." Deviations from purely multip
255 dation, the newly developed SYNTAX score II, termed SYNTAX score II 2020, showed a helpful discrimina
258 re but heterogeneous developmental syndrome, termed syt1-associated neurodevelopmental disorder.
260 rt of a complex mixture of chemical analogs, termed taxoids, which complicates its production in pure
261 for the disorder-to-order transition in IDPs termed "templated folding," whereby the binding partner
262 rientational ordering of cellulose crystals, termed texturing in materials science, represents a prev
263 target of a group of chronic liver diseases termed the "cholangiopathies," in which cholangiocytes r
264 d noise, an untargeted peak detection method termed the "enhanced TIC algorithm" was developed for co
265 rein the OT, which may be more appropriately termed the "tubular striatum" (TuS), is a neural system
266 returns a unique, normalized representation termed the 'Contextual Allele'. The SPDI data model, wit
270 familial hypercholesterolemia (FH)-have been termed the Centers for Disease Control and Prevention Ti
279 flammatory and growth-stimulatory molecules, termed the senescence-associated secretory phenotype (SA
280 est and a complex proinflammatory secretome, termed the senescence-associated secretory phenotype (SA
285 ponse of plants to high ambient temperature, termed thermomorphogenesis, is characterized by hypocoty
286 hat was developed to predict the boundaries (termed Theta(1) and Theta(2)) separating the three phase
287 h2 locus upstream of the PEST domain, and we termed this model Notch2(tm1.1Ecan) Heterozygous Notch2(
288 er targeted sample multiplexing experiments, termed Tomahto, and present its implementation on the Or
290 ROUNDInduction of innate immune memory, also termed trained immunity, by the antituberculosis vaccine
291 Induction of innate immune memory, also termed trained immunity, contributes toward protection a
294 We identify two major classes of PVT neurons-termed type I and type II-that differ in terms of gene e
296 ly sensitive, rapid and multiplexed protocol termed UbiFast for quantifying ~10,000 ubiquitylation si
297 et cells, the viral core undergoes a process termed uncoating, during which CA molecules are shed fro
300 nvestigated the functions of a small protein termed VPg or 3B, which acts as a primer in the replicat