ライフサイエンスコーパス: termination

1 in is related to a medial-to-lateral axis of termination.

2 ely mechanism of action is delayed RNA chain termination.

3 nt than bursting near movement initiation or termination.

4 n of the intraosseous artery and its site of termination.

5 e initiation, reorganization, and senescence termination.

6 nt for correct usage of polyA sites for mRNA termination.

7 tions in ten genes involved in transcription termination.

8 e PTC and demonstrate their critical role in termination.

9 to promoter DNA, initiation, elongation, and termination.

10 e-polarization and shoot gravitropic bending termination.

11 o resolve R-loops and promotes transcription termination.

12 tant virus that fails to block transcription termination.

13 d AZT-TP to the telomeric end, causing chain termination.

14 ition between initiation, translocation, and termination.

15 f the ictal rhythm as the seizure approaches termination.

16 a reaction always brought to a close by its termination.

17 are dose-limiting and can lead to treatment termination.

18 ss also triggers Rho-dependent transcription termination.

19 udy interpretation is limited by early trial termination.

20 ownstream declines in channel size and local termination.

21 le without general disruption of translation termination.

22 e than 24 hours following status epilepticus termination.

23 on of a persistent PTC is a prerequisite for termination.

24 weeks, changed from 52 weeks following early termination.

25 ional fidelity by involvement in translation termination.

26 y-induced global impairment of transcription termination.

27 ylate sequence determinant for transcription termination.

28 sensitive to changes in lncRNA 3' processing/termination.

29 n Explosion and determined the nature of its termination.

30 l nuclear role for Gle1 during transcription termination.

31 or that mediates regulation of transcription termination.

32 domain of RNA polymerase in anticipation of termination.

33 ed to their preictal waveforms after seizure termination.

34 ading cause of preclinical and clinical drug terminations.

35 uggests the occurrence of different modes of terminations.

36 iscarriages, and 74 (22%) elective pregnancy terminations.

37 stern Australia from 1980 to 2015, excluding terminations.

38 Manufacturing delays resulted in early termination (376/486 participants, 77% of target).

39 d, RRF depletion leads to enrichment of post-termination 70S complexes in 3'-UTRs.

40 was previously known to target only the post-termination 70S complexes; our results reveal a new role

41 se was seen at 54 AFDs (77.1% of AFDs; 21 AF termination and 33 cycle length slowing) and occurred in

42 4) has been found to have a critical role in termination and adaptation of visual and olfactory signa

43 ta highlight the importance of transcription termination and antitermination in the evolution of bact

44 ell, studying the mechanism of transcription termination and antitermination.

45 and trial interpretation is limited by early termination and inconsistent findings for nicotine and n

46 iated with Integrator-mediated transcription termination and indicate that control of productive elon

47 vealing principles of eukaryotic translation termination and laying the foundation for new therapeuti

48 uct of the surgical procedure; (5) procedure termination and lung re-expansion; (6) chest drainage.

49 triggers widespread premature transcription termination and mRNA shortening.

50 these was eRF1, which regulates translation termination and nonsense-mediated decay (NMD).

51 f complications following status epilepticus termination and return to premorbid functional baseline.

52 An in-depth analysis of their different edge termination and stacking arrangement was performed via D

53 t catheters recently showed high rates of AF termination and subsequent freedom from AF.

54 e effect of RAC/Ssb mutations on translation termination and the absence of an effect on the [URE3] p

55 ons of NTP pools cause a gradual decrease in termination and the resulting read-through increases ful

56 scriptional pre-mRNA splicing, transcription termination, and consequences of spurious transcription.

57 mo/hetero products based on the various edge-termination, and different stacking of the two layers.

58 hanistic link between viral infection, bloom termination, and mass carbon export events and highlight

59 ystems with known defects in transcriptional termination, and show how these results can be leveraged

60 er (m)RNA export, translation initiation and termination, and stress granule dynamics.

61 export, translation initiation, translation termination, and stress granule formation.

62 ly affect the onset of breeding but also its termination, and thus the length of the breeding period.

63 exploiting the known exposed surface planes, terminations, and coordiations of [Formula: see text] na

64 Complications after status epilepticus termination are frequent and associated with no return t

65 Hydroxide and fluoride terminations are identified, found to be intimately mixe

66 rols that affect the structure and timing of terminations are still poorly understood.

67 The concept of early termination as an important means of transcriptional con

68 minished role of Rho-dependent transcription termination, as well as the prevalence of mRNA leaders t

69 ne, selenium, bromine, and tellurium surface terminations, as well as bare MXenes (no surface termina

70 employed to trigger premature transcription termination at many protein-coding genes, thereby attenu

71 Here, we investigate transcription termination at piRNA loci.

72 (RDV-TP) at position i causes delayed chain termination at position i + 3.

73 nd (BDD) electrodes with hydrogen and oxygen terminations at a series of temperatures up to 125 degre

74 lled the onset of the second stage, when the termination became a non-reversible and global phenomeno

75 ric principles and mechanistic congruency of termination between bacteria and eukaryotes, in which an

76 ble the ribosome to overcome the translation termination blockage imposed by an arrest peptide.

77 e in dominant frequency between VF onset and termination but none of the other parameters significant

78 r=-0.3, P=0.047) and predictive of rapid VT termination by a single radiofrequency application (r=-0

79 intracardiac recordings and referenced to AF termination by ablation.

80 These molecules also inhibit translation termination by an unknown mechanism.

81 hes, we show that PF846 inhibits translation termination by arresting the nascent chain (NC) in the r

82 ulate to toxic levels that elicit precocious termination by CPF/Rhn1.

83 nderstanding the regulation of transcription termination by other viruses, cellular stress and cancer

84 CK1delta prevents termination by phosphorylating and inhibiting SSUP-72.

85 ed by MED26 promotes efficient transcription termination by Pol II through interaction with CBC-ARS2

86 Clamp opening is proposed to promote termination by releasing RNAP-nucleic acid contacts.

87 rtant for preventing premature transcription termination by Rho factor.

88 echanisms to prevent premature transcription termination by Rho, a conserved bacterial transcription

89 ults suggest that nucleosomes can facilitate termination by serving as a barrier to transcription and

90 s of translation-initiation, elongation, and termination-cells use stimuli to tune translation rate a

91 splicing factor mutants comprise a premature termination codon (PTC) and are therefore potential targ

92 e therapeutically desirable when a premature termination codon (PTC) is found in a critical gene.

93 ous effects of the position of the premature termination codon (PTC) on the CFTR protein function.

94 des a frame-shifted protein with a premature termination codon (PTC) predicted to elicit degradation

95 se progranulin mutations contain a premature termination codon (PTC), thus progranulin haploinsuffici

96 del from Igh (Ter5H) mice having a premature termination codon at position +5 in leader exon of Igh (

97 The duplication introduces a premature termination codon leading to nonsense-mediated mRNA deca

98 splicing to a cryptic exon with a premature termination codon.

99 noglycosides stimulate readthrough of normal termination codons (NTCs) genome-wide.

100 MD gene leading to the presence of premature termination codons (PTC).

101 tion of mRNA harboring premature translation termination codons (PTCs) serves to protect cells from a

102 des some but not all mRNAs bearing premature termination codons (PTCs).

103 are caused by the introduction of premature termination codons (PTCs).

104 In addition to premature termination codons, plant microRNAs can also direct the

105 re generated larger responses and more early terminations compared with NAC.

106 eracting with RNA, Rho forms a specific "pre-termination complex" (PTC) with RNAP and elongation fact

107 transcription mechanisms, it is unknown how termination complexes are disassembled, especially in wh

108 coordinating DDX1 function in transcription termination complexes.

109 of firm age estimates for older Pleistocene terminations confounds attempts to test the persistence

110 r dichroism further suggest that the surface termination conversion breaks the local octahedral symme

111 re, an atomic-scale MIT triggered by surface termination conversion in SrRuO(3) ultrathin films is re

112 As the surface termination converts from SrO to RuO(2) , a highly insul

113 of TDP-43 allowed transcription of an early termination cryptic axon, resulting in truncated, nonfun

114 Patients were followed up until membership termination, death, or the study end date of December 31

115 cause widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in host

116 dence that Xrn1 is involved in transcription termination downstream of polyadenylation sites.

117 consequently, induce premature transcription termination downstream of the cleavage site in an XRN2-d

118 Sites of entrainment, pace-mapping, and termination during ablation were used to define the VT s

119 For patients with AF termination during ablation, 82% remained AF-free and 74

120 g has been associated with a high rate of VT termination during radiofrequency ablation as well as no

121 Mean 'final' gait termination EMG activity (right gastrocnemius) was great

122 Uniform and effective termination engineering at the SrRuO(3) (001) surface ca

123 a single-chain-elongation or a single-chain-termination event during ruthenium-catalyzed polymerizat

124 e mechanism of the chain-walking process and termination events.

125 s are highly sensitive to chain-transfer and termination events.

126 signaling pathway, we found that replication termination factor 2 (RTF2) restricts influenza virus at

127 Rho is a general transcription termination factor playing essential roles in RNA polyme

128 efects absent CPF subunits Ctf1 and Dis2 and termination factor Rhn1.

129 by Rho, a conserved bacterial transcription termination factor that rapidly terminates untranslated

130 with the discovery of the Rho transcription termination factor, and the regulatory mechanism of tran

131 self-propagating amyloid of the translation termination factor, Sup35p.

132 ctional analyses suggest that rho, and other termination factors across life, may use analogous strat

133 Only select sequences or transcription termination factors can disrupt the otherwise extremely

134 RNA polymerase II CTD and the 3' processing/termination factors CPF and Rhn1, mutations of which res

135 , are aberrantly transcribed due to upstream termination failure (read-in genes), and novel transcrip

136 depletion, consistent with a PP1 function in termination first uncovered in yeast.

137 016 ISTH guidance against elective pregnancy termination for fear of DOAC embryotoxicity and the reco

138 lications occurring after status epilepticus termination for no return to premorbid neurologic functi

139 Early trial termination for safety concerns and the possibility that

140 Approximately 20% of A32 terminations formed synapses on inhibitory neurons in A2

141 d laminar patterns of projection origins and terminations has been tested.

142 posit from the Iberian Peninsula that covers Termination II (T-II) and whose chronology was synchroni

143 use RNA polymerase II (Pol II) transcription termination in cultured cells and mice.

144 ed liver injury (DILI) is a leading cause of termination in drug development programs and removal of

145 the designed channel current for arrhythmia termination in human atrial myocytes using dynamic clamp

146 We provide an updated view of transcription termination in human cells, highlighting common themes a

147 nates most densely in Layer III with sparser termination in Layers I, II, and V.

148 red Clb3 or Ama1 production restored meiotic termination in the absence of autophagy.

149 iculum are related to a rostrocaudal axis of termination in the entorhinal cortex.

150 ssumed that all MCs have similar patterns of termination in the inner molecular layer of the DG, we d

151 rsal and ventral DG have similar patterns of termination in the inner one-third of the dentate molecu

152 tion of eQTLs in systems where transcription termination is blocked.

153 Promoter-proximal and premature termination is common and might in turn regulate gene ex

154 We show that termination is completely abolished by rapid elimination

155 As termination is defined by the release of product RNA fro

156 PHO lncRNA termination is governed by the Pol2 CTD code and is subj

157 Furthermore, ASO-directed transcription termination is mediated by the nuclear exonuclease XRN2.

158 (2020) also demonstrate that Pol II termination is not observed with gapmers targeting the 3

159 Efficient transcription termination is particularly critical for gene-dense bact

160 ycle, the role of chromatin in transcription termination is poorly understood.

161 (MERS-CoV) have revealed that delayed chain termination is RDV's plausible mechanism of action.

162 Transcription termination is triggered by cleavage of nascent transcri

163 if a ribosome remains bound to an mRNA after termination, it may re-initiate downstream.

164 electrodes, with hydrogen and oxygen surface terminations, it is determined that the electrochemical

165 nt October 30, 2014, to June 14, 2017; study termination January 8, 2020; last patient visit May 14,

166 Disruption of transcription termination leads to readthrough transcription past the

167 Factor-dependent transcription termination mechanisms are poorly understood.

168 Although some transcription termination mechanisms have been debated for decades, re

169 to complex ophiobolins leveraging disparate termination modes of a radical polycyclization cascade f

170 tions between initiation, translocation, and termination modes.

171 Pol II transcribes multiple gene types, its termination occurs in a variety of ways, with the polyme

172 aturation ~6 h later, defining the onset and termination of a destabilization window of cocaine memor

173 m the gastrointestinal tract, which promotes termination of a meal.

174 ime (interval between the initiation and the termination of a visit).

175 cholinesterase (AChE) is fundamental for the termination of ACh impulse transmission.

176 allowing nearly instantaneous initiation and termination of activation signal, respectively.

177 ted PKR kinase activation as a marker of the termination of adaptation and initiation of inflammation

178 the ethical issues that this practice poses: termination of advanced cardiopulmonary resuscitation, e

179 rticipant, including exact time of onset and termination of all AF episodes.

180 ltaneously mutating N65 and N82 causes early termination of alpha(1D)-AR between transmembrane domain

181 Before termination of autologous SCT, EFS rates of patients in

182 their concurrent dissociations in intrinsic termination of bacterial transcription.

183 Termination of BIR and creation of an ectopic telomere i

184 acilitate rapid invader clearance and ensure termination of CRISPR interference to limit self-toxicit

185 All parameters were reversible following termination of DREADD-mediated Gq signaling.

186 TRIAD1, an E3 ubiquitin ligase required for termination of emergency granulopoiesis and leukemia sup

187 ecause of decreased TRIAD1 activity, impairs termination of emergency granulopoiesis during the innat

188 ng GUANYLATE BINDING PROTEIN1, induces early termination of endoreduplication followed by late divisi

189 im analysis and subsequently recommended the termination of enrollment and the reporting of the resul

190 alled Fe(tet1) termination, that the biphase termination of Fe(3)O(4)(111)/Pt(111) consists of FeO an

191 We trace the termination of Fermi-surface reconstruction to two hole

192 ent with a different anti-VEGF medication or termination of health plan coverage.

193 irst time, we demonstrate that the premature termination of host gene transcripts upstream of iCGIs i

194 reas of high immunity reflected by immediate termination of imported viruses.

195 de a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restor

196 ed in the second-stage morphology exhibiting termination of lamellae formed during the first growth s

197 o ensure correct initiation, elongation, and termination of mRNA transcription.

198 itionally, tolerance was thought to occur by termination of mu-opioid receptor (MOR) signaling via de

199 4-driven differentiation, resulting in early termination of nephrogenesis and severe renal dysgenesis

200 MED26 recruits LEC to modulate transcription termination of non-polyadenylated transcripts including

201 endogenous regulator of inflammation through termination of nuclear factor (NF)-kappaB activation as

202 cell (ESC) identity by preventing premature termination of numerous transcripts at cryptic cleavage/

203 The detection of subclinical RD or early termination of outer retinal layers in selected cases ma

204 DNA binding and controls both activation and termination of p53-mediated transcriptional programs at

205 exclusion of structural alerts and possible termination of reactive metabolite-positive compounds.

206 r from treslin to E2F1, which results in the termination of replication initiation.

207 Incorporation of RDV-TP at position i caused termination of RNA synthesis at position i+3.

208 Incorporation of ddhCTP causes premature termination of RNA synthesis by the RNA-dependent RNA po

209 the distantly related Lassa virus RdRp, and termination of RNA synthesis was not observed.

210 neurons can contribute to the initiation and termination of SWRs.

211 F3, the gene encoding TF, causing premature termination of TF (TFshort) in a woman with unexplained

212 d for hundreds of milliseconds following the termination of the acoustic stimulus.

213 Understanding of the course, location, and termination of the artery enhances the precision of a cl

214 s were stable, inducible in adults after the termination of the critical period for ocular dominance

215 gating and ii) generate an ionic current for termination of the detected arrhythmia.

216 mber of in trial patients, which resulted in termination of the drug development programme.

217 ntific Monitoring Committee due to the early termination of the ENDO trial (NCT01728116) by the US Fo

218 ache during (ictal) or after (postictal) the termination of the event.

219 At the predefined termination of the experiment at 6 wk, 7 of 7 and 3 of 7

220 The most common (22%) site of termination of the intraosseous artery is at the mesial

221 O vapour abundances for models investigating termination of the Paleoproterozoic glaciations, and hig

222 Reductive termination of the photocatalytic cycle generates an ani

223 ves only to maintain channel activity beyond termination of the PKA signal.

224 ntal questions still remain about the atomic termination of the QDs.

225 aining RhoA-mediated transcription after the termination of the receptor signaling.

226 crucial mitotic regulator that triggers the termination of the SAC and enables chromosome segregatio

227 nd safety monitoring board recommended early termination of the study prior to enrollment of 440 pati

228 t and a reduced sample size due to the early termination of the study.

229 ted in the context of wide CIs and premature termination of the trial.

230 c progression involves checkpoint-controlled termination of these events when all homologue pairs ach

231 scovery of the role of bacterial RNase J1 in termination of transcription suggests common allosteric

232 with promoter-proximal Pol II, resulting in termination of transcription.

233 e protein production by inducing a premature termination of translation, which triggers messenger RNA

234 d a healthy baby boy was born 7 months after termination of treatment.

235 ctor into Cas9 target sites caused premature termination of Ube3a-ATS at the vector-derived polyA cas

236 gene derepression by premature transcription termination of upstream interfering noncoding RNAs.

237 ization, reduction in TGFbeta1 signaling and termination of vascular growth.

238 fined isthmus dimensions, confirmed by rapid termination of VT during radiofrequency delivery.

239 ps firmly and equally interpret peace as the termination of war and bloodshed (termed "negative peace

240 ently promotes Rho-independent transcription termination of ytgR, thereby de-repressing P(trpBA).

241 somes in fetal ovarian samples from elective terminations of pregnancy.

242 on and relocation of brain areas can predict terminations of several white matter tracts in temporo-p

243 hermodynamic origin and is controlled by the terminations of the (111) surfaces of the crystal.

244 are typically configured as presynaptic axon terminations onto postsynaptic dendrites or somata, givi

245 An ablation response was defined as AF termination or cycle length slowing >=30 ms.

246 ge, or as drastic as premature transcription termination or degradation of polyubiquitylated Pol II a

247 this action results in either transcription termination or elongation rescue, which rely on ATP-depe

248 rgent replication were divided into sites of termination or large constant timing regions consisting

249 Radiometric dating of glacial terminations over the past 640,000 years suggests pacing

250 acer injection placement to determine S1 CST termination patterns within the cord.

251 +) release event, between the initiation and termination phases (which are unaltered compared to the

252 Traditional models of transcription termination postulate that hexameric Rho loads onto RNA

253 RNA Pol II and drive premature transcription termination, potently attenuating the activity of target

254 ctron microscopy (cryo-EM) structures of two termination process intermediates.

255 for remote functionalization through various termination processes.

256 c shift toward distal sites of transcription termination produces transcript signatures that are cruc

257 (mRNA)-specific initiation, elongation, and termination rates.

258 ry, after releasing RNA product at intrinsic termination, recycling RNAP diffuses on the DNA template

259 displace MukBEF from the 800 kbp replication termination region (ter).

260 1-dependent slowing down of polymerases over termination regions facilitates their pursuit/capture by

261 Termination removes the repressive DNA structure, whereu

262 Premature termination requires RNA cleavage by the endonuclease su

263 ated with the [MnBi(2)Te(4)] or [Bi(2)Te(3)] termination, respectively.

264 Our data reveal a failure in post-termination ribosome recycling in UPF1 ATPase mutants.

265 Following termination, RNAP almost always remains bound to DNA and

266 After termination, RNAP is thought to initiate the next round

267 in transcription initiation, elongation, and termination, several noncoding (nc)RNAs also function as

268 increased dust loads during the Green Sahara termination shifted the Walker circulation eastward and

269 -y)Nb(y)CT(x), where T(x) stands for surface terminations) showing the evolution of electronic and op

270 e 4th position of the gene end transcription termination signal of the G gene of currently circulatin

271 4th position of the G gene end transcription termination signal.

272 rminus, preceding the gene end transcription termination signal.

273 transcription start sites, and transcription termination sites at single-nucleotide resolution.

274 ckage to infer the transcriptional start and termination sites of primary transcripts from genomic ru

275 ability to identify ventricular tachycardia termination sites through high-density mapping of decele

276 ons, introns, intergenic, TTS (transcription termination sites) and promoters; (iii) fourteen (14) ge

277 script isoforms that vary in their start and termination sites.

278 rapid flowering (SP5G) and precocious growth termination (SP).

279 An assessment of 11 radiometrically dated terminations spanning the past million years suggests th

280 separated by two obliquity cycles, with each termination starting at the same high phase of obliquity

281 Pin1 as a positive effector of 3' processing/termination that acts via Ssu72.

282 lts reveal a core mechanism of ABA signaling termination that is critical for seed germination and se

283 111) is terminated by the so-called Fe(tet1) termination, that the biphase termination of Fe(3)O(4)(1

284 ng replication forks meet during replication termination, the CMG (Cdc45-MCM2-7-GINS) helicase is pol

285 During the last the two terminations, the BSM was triggered by different detaile

286 volving oxidative addition, cyclization, and termination through intermolecular nucleophile capture h

287 s were collected at 0, 2, 4, 8, and 12-week (termination) time points to monitor PV cross-sectional a

288 nd biological processes target transcription termination to misregulate gene expression.

289 PP1 govern pause release and the elongation-termination transition, respectively.

290 orates domains, coding sequence position, U6 termination (TTT), restriction sites, polymorphisms and

291 that favor 'precocious' lncRNA 3'-processing/termination upstream of the mRNA promoters.

292 ich decreases the concentration required for termination upstream of the ribD coding sequence.

293 Termination via a chain-transfer reaction yields the ter

294 The former invokes termination via conformational changes in the transcript

295 epresents an empty layer) by controlling the termination via molecular beam epitaxy.

296 The most common site of termination was at the mesial of the second molar (22%),

297 ulation that restricts CMG ubiquitylation to termination was unknown, as was the mechanism of disasse

298 inations, as well as bare MXenes (no surface termination), was demonstrated.

299 urface slabs with different possible surface terminations were generated from the CsPbBr(3) crystal s

300 the S861G mutation in RdRp eliminates chain termination, which confirms the existence of a steric cl