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1 ups (i.e., phenylureas, tertiary amides, and tertiary amines).
2 for a sacrificial electron donor, usually a tertiary amine.
3 noline and aporphine substrates possessing a tertiary amine.
4 d formation was driven by the oxidation of a tertiary amine.
5 tion of a variety of primary, secondary, and tertiary amines.
6 thoxycarbonyl)isocyanate upon treatment with tertiary amines.
7 the slow nitrosation rates hypothesized for tertiary amines.
8 d the formation of NDMA by chloramination of tertiary amines.
9 e design of a series of substituted N-phenyl tertiary amines.
10 reaction with feedstock carboxylic acids and tertiary amines.
11 with about 60% of drug candidates containing tertiary amines.
12 hols, alcohol-acids, as well as reduction to tertiary amines.
13 umber of enantioselective syntheses of alpha-tertiary amines.
14 iterative approach to access functionalized tertiary amines.
15 alcohols and N-hydroxylamine esters to form tertiary amines.
16 amines to afford alpha-trisubstituted-alpha-tertiary amines.
17 r the synthesis of N-alkylated secondary and tertiary amines.
18 one-pot synthesis of 1,2- and 1,3-oxygenated tertiary amines.
19 alkane products allows rapid access to alpha-tertiary amines.
20 ation reactions during chloramination of the tertiary amines.
21 elective palladium-catalyzed alkenylation of tertiary amines.
22 achieved from the appropriately substituted tertiary amines.
23 e synthesis of enantioenriched secondary and tertiary amines.
24 complete reduction to give the corresponding tertiary amines.
25 y binding hot spot, preferably binding small tertiary amines.
26 egy for the streamlined synthesis of complex tertiary amines.
27 on does not exhibit the ordinary basicity of tertiary amines; 3 can be extracted from acidic media wi
28 the enantiomers of 3b and the corresponding tertiary amine 33b revealed that the eutomers are (2S,6S
29 difications to the head group containing the tertiary amine, a tail group that extends away from this
31 With Lewis basic C-H donors such as THF and tertiary amines, a decrease in k(H) with increasing Lewi
35 , sugar, hydroxyl, thiophene, sulfur, azide, tertiary amines, alkyne, vinyl, or phosphonate groups we
36 P attachment, and simultaneously incorporate tertiary amines along with carboxyl and/or hydroxyl grou
39 lic substitution reaction between the parent tertiary amine and a novel derivatizing reagent, di-tert
41 (ii) downstream protoberberines containing a tertiary amine and forming quaternary intermediates dest
43 lines that were not affected by the type of tertiary amine and treatment conditions, suggesting that
46 ccompanied by the pyramidal inversion of the tertiary amines and by the rotation of the tribenzylamin
50 permits iterative alkyl group transfer from tertiary amines and demonstrates a deaminative strategy
51 compounds, including primary, secondary, and tertiary amines and quaternary ammonium compounds, all s
53 group, with the highest clearance rates for tertiary amines and sulfates and no clearance of QACs.
54 e photochemical mechanisms of coumarin-caged tertiary amines and then optimize the major pathway usin
55 ters, amides, ethers, acetals, nitriles, and tertiary amines and, therefore, should be applicable to
56 in k(H) was observed going from secondary to tertiary amines and, with tertiary amines, on increasing
57 in total) observed was between surfactants (tertiary amines) and endogenous metabolites (fatty acid
58 strongly ionized bases (primary, secondary, tertiary amines), and a pair of quaternary ammonium comp
60 g group except for sterically hindered alpha-tertiary amines, and a practical catalytic system for C(
61 ssed along the C(3) axis passing through the tertiary amines, and the two tribenzylamine platforms ar
62 commercially available N-methyl substituted tertiary amines, and therefore it represents an attracti
63 e MAO-N-D5 variant, which is able to oxidise tertiary amines, appear to influence the active-site env
65 st, a broad range of alkylated secondary and tertiary amines are obtained in good to excellent yields
66 ntermediates resulting from the oxidation of tertiary amines are trapped during the photoinduced elec
67 -dimethyl 5-HT, in which the side chain is a tertiary amine, are found in the computational simulatio
72 tetraketones using cyclic-1,3-diketones and tertiary amines as alkyl synthons under 18 W blue LED ha
73 n the application of primary, secondary, and tertiary amines as efficient organocatalysts for the de
74 es, which is the first example of the use of tertiary amines as intermolecular nucleophiles in metal-
77 ocyclic and aliphatic primary, secondary and tertiary amines as well as N-methylamines and more compl
78 a, select protonated primary, secondary, and tertiary amines as well as tetramethylammonium with 19-2
80 The selective sp(3) C-N bond activation of tertiary amines at the less steric side using O2 as a so
84 1 with primary alcohols in the presence of a tertiary amine base results in salts of intact TriMP alk
88 enewable sources, we synthesized a series of tertiary amine-based ILs from aromatic aldehydes derived
91 step in the intramolecular C-H borylation of tertiary amine boranes activated with catalytic amounts
92 an extended structure containing a terminal tertiary amine, but this had no beneficial effects on bi
94 tudied for releasing primary, secondary, and tertiary amines by direct photochemical breaking of the
95 recurring events: the in situ methylation of tertiary amines by PO(OMe)(3), Ni-catalyzed C-N bond cle
96 rimary amines--over branched, secondary, and tertiary amines--by a two-step process involving a proto
99 stand design principles how the structure of tertiary amine catalysts having N, N-dimethyl groups can
101 ntrol (7) revealed that the presence of a N1 tertiary amine center imparted a significant reduction i
102 al complexation process, it is proposed that tertiary amine compounds, having N-substituents which ar
107 a model compound (quinuclidine) and to three tertiary amine-containing drugs (cinnarizine, loxapine,
108 ion while olefins undergo aziridination, and tertiary amine-containing natural products are converted
109 analysis, we describe herein a new series of tertiary amine-containing pyrazolones and their structur
111 rbamate bond; however, the ability to employ tertiary-amine-containing bioactive molecules has been e
112 ino)ferrocene (DPPF) in combination with the tertiary amine Cy(2)NMe proved effective in the olefinat
113 tions this happens even if the corresponding tertiary amine (DDMA) is added, instead of DDMA-Br.
114 aternary ammonium compound clofilium and its tertiary amine derivative LY97241 were used to analyze m
115 a route to synthesize valuable chiral alpha-tertiary amines directly from an isomeric mixture of alk
116 easily accessible a-silyl amine reagents or tertiary amines directly, secondary and tertiary amine m
117 (N(4)S(thiolate))Fe(II) complex, containing tertiary amine donors, [Fe(II)(Me(4)[15]aneN(4))(SPh)]BP
121 Previous examples have principally been tertiary amines, especially those with cyclic scaffolds.
124 tin, and ferric TRENCAM, which substitutes a tertiary amine for the macrocyclic lactone ring of ferri
125 CI: 1.40, 2.73); odds ratios associated with tertiary amines from the lowest tertile of nitrite intak
126 leton, hexamethylindotricarbocyanine, with a tertiary amine functionality that was electronically cou
128 tones; however, the direct polymerization of tertiary amine functionalized cyclic esters has remained
129 ines to give the corresponding secondary and tertiary amines generally in high yields (up to 96%) and
130 hat in the presence of a proton source and a tertiary amine generates the corresponding alpha-difluor
131 heterocycles like azaacene and secondary and tertiary amines give exclusively the dyes containing a t
134 metal-organic framework functionalized with tertiary amine groups that exhibits high capacities for
135 n alkylating agent, to convert polymer-bound tertiary amine groups to less chloramine-reactive quater
136 of the oppositely charged paper (protonated tertiary amine groups) and the anionic groups of the rea
137 erionic compounds with hydrocarbon ester and tertiary amine groups, the bulk polymer itself is elasto
140 o-catecholato) with equimolar AlCl(3) and a tertiary amine has been applied to a wide range of arene
141 o nitrosatable drugs, including secondary or tertiary amines, has been associated with preterm birth.
143 optimal temperature, affording chiral alpha-tertiary amines in excellent yields with high enantiocon
144 provides high yields in methanol, release of tertiary amines in MeCN/water can improve yields and red
146 en investigated by chloramination of several tertiary amines in the absence and presence of bromide i
148 esters react with heteroaromatic and certain tertiary amines in the presence of an oxidant (I(2)) to
150 trosatable drugs, particularly secondary and tertiary amines, in conjunction with higher levels of di
152 f linear and branched primary, secondary and tertiary amines including N-methylamines and molecules u
153 ing a broad range of alkylated secondary and tertiary amines, including fluoroalkyl-substituted anili
155 displacement of a methyl group attached to a tertiary amine is a reaction without an obvious preceden
159 HAS polymers possess primary, secondary, and tertiary amines, leading to multiple chemisorption react
161 quenching of the Ir(3+) excited state by the tertiary amine leads to the ammonium radical cation, wit
162 eaction of both acyclic and cyclic aliphatic tertiary amines led to the formation of 2- N, N-dialkyla
163 tions of copper(II) bromide and an aliphatic tertiary amine ligand (Me6-Tren; Tren = tris(2-aminoethy
164 ows the construction of stable secondary and tertiary amine-linked protein conjugates without affecti
167 rapping reagent and an exquisitely selective tertiary amine-mediated hydrogen-atom abstraction at the
169 argensis was able to biotransform two of the tertiary amines, mianserin (MIA) and ranitidine (RAN), e
170 odifiers without amine groups nor those with tertiary amine moieties are capable of adsorbing on the
171 s or tertiary amines directly, secondary and tertiary amine moieties can be installed onto monoaryl a
173 , the 9-aza-APs carrying a distal lipophilic tertiary amine moiety in both chains were capable of ove
174 could be explained by the speciation of the tertiary amine moiety of TRA, with apparent second-order
175 ) cage contains 12 amide NH groups plus four tertiary amine N groups, the latter of which are positio
176 rein, we demonstrate for the first time that tertiary amine N-oxides, an oxidative degradation produc
179 s location in the membrane placed the drug's tertiary amine near the phosphate of the headgroup, its
180 t method for accessing N-aryl alpha-branched tertiary amines, new catalysts have been designed to sup
184 likely than were control women to have taken tertiary amines (odds ratio = 1.60, 95% confidence inter
185 es that MeTr decreases the acidity of the N5 tertiary amine of CH3-H4folate by 1 pK unit in both wate
186 mechanism in which both the thiourea and the tertiary amine of the catalyst are involved productively
188 strong charge-charge interaction between the tertiary amine of the ligand and an aspartic acid residu
191 the terminal primary amines and the interior tertiary amines of the dendrimers to the observed EMF re
194 are selective blockers of 5HT reuptake, and tertiary amines of the trans compounds are less potent t
196 ted and experimental (13)C shifts of the six tertiary amines of unambiguous structure are found.
197 tive reveals that the positive charge of the tertiary amine on the trienyl arm induces G selectivity.
198 from secondary to tertiary amines and, with tertiary amines, on increasing steric hindrance at nitro
200 ators of cholinesterases (ChEs) that contain tertiary amine or imidazole protonatable functional grou
201 ive aldol reactions realized by using either tertiary amines or a dizinc aldol catalyst constitute tw
202 talyst, provides a direct synthesis of alpha-tertiary amines, or their corresponding gamma-lactams.
203 polymer bearing a seven-membered ring with a tertiary amine (PC7A)-activates innate-immunity pathways
204 surfactants containing both zwitterionic and tertiary amine pendent groups were synthesized for stabi
207 Mechanistic investigation revealed that tertiary amines predominately operate as Bronsted rather
209 electivities are observed for secondary over tertiary amine products, even though the secondary amine
210 ned syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficul
212 hydroxide, ammonia, primary, secondary, and tertiary amines provide evidence that carbamate, rather
214 ch proved fully operative in the presence of tertiary amines, quinoline, and other Lewis basic sites.
217 to access various a- and B-boron-substituted tertiary amines, respectively, from common secondary ami
218 e DCA-loaded compound 10, characterized by a tertiary amine scaffold, because it exhibited enhanced (
219 n with melamine acetaldehyde, resulting in a tertiary amine side chain that affords both peptide solu
220 cated that 4-substituted amino groups with a tertiary amine side chain, such as chloroquine, were ass
223 and the length of the tether connecting the tertiary amine site used for ionization via protonation
225 y simple and highly efficient C(2)-symmetric tertiary amine-squaramide organocatalyst for asymmetric
226 c and experimental data strongly suggest the tertiary amine-stabilized dichlorosilylene to be the mos
227 amino acids), but not from secondary amines, tertiary amines, sterically hindered primary amines, or
228 eaction conditions, with good generality for tertiary amine structure and moderate to excellent yield
231 e H(8)BINOL-AM compounds containing 3,3'-bis-tertiary amine substituents are synthesized by using a o
232 ine-amide-dithiol (AADT) chelates containing tertiary amine substituents as small-molecule probes for
233 ine-amide-dithiol (AADT) chelates containing tertiary amine substituents were synthesized and shown t
236 in the dark in the presence of an excess of tertiary amines, such as tris[2-(dimethylamino)ethyl]ami
237 loying a series of sterically differentiated tertiary amines suggest that the steric nature of the am
239 for a switchable cationic surfactant, e.g., tertiary amine surfactant (Ethomeen C12), is 2.22% in DI
242 affold types, one a bicyclic iodo-vinylidene tertiary amine/tertiary alcohol and the other, a spirocy
244 ral helical (thio)urea oligomer and a simple tertiary amine that is able to promote the Michael react
245 catalyst is a simple tetrapeptide bearing a tertiary amine that may function as a Bronsted base.
246 explains the capsule's high affinity toward tertiary amines that are protonated and therefore encoun
247 (CSIA) of NDMA during chloramination of four tertiary amines that produce NDMA at high yields, namely
248 itiated electron transfer from a sacrificial tertiary amine, the reduced intermediate of complexes co
250 ctional chiral phosphines or multifunctional tertiary amine-thioureas as the catalyst, respectively.
251 ary amides from aryl boronic acids and inert tertiary amines through the oxidative carbonylation via
252 ion of the catalyst, which is reduced by the tertiary amine to produce the single-electron reducing a
256 effective for the dehydrogenation of simple tertiary amines to give enamines than the previously rep
257 hydrogenation of several beta-functionalized tertiary amines to give the corresponding 1,2-difunction
260 queous mixtures of commonly used primary and tertiary amines to study the influence of the different
261 ts oxidative N-dealkylation/carbonylation of tertiary amines to tertiary amides by using molecular ox
262 strated (conversion to quaternary centers, C-tertiary amines) together with application of the method
264 s, are rapidly and quantitatively reduced to tertiary amines under mild conditions with low catalyst
265 osition of alpha-diazo carbonyls tethered to tertiary amines underwent a benzylic Stevens [1,2]-rearr
268 oped for the synthesis of a diverse range of tertiary amines using inexpensive polymethylhydrosiloxan
270 eneral method for the difluoromethylation of tertiary amines, using diethyl bromodifluoromethylphosph
271 en-deuterium exchange of biologically active tertiary amines utilizing the borrowing hydrogen methodo
273 ylation of primary and secondary amines into tertiary amines was confirmed by FTIR and NMR analysis.
275 tions, a range of both cyclic and open chain tertiary amines was tested as substrates, resulting in y
276 tems for the chloramination of secondary and tertiary amines, we investigated the kinetics of precurs
278 aryl sulfonamides, while bulky secondary and tertiary amines were preferred at the benzylic amine pos
280 monium salts, derived from alkyl halides and tertiary amines, were the intermediates to yield thioest
281 ive deracemisation of primary, secondary and tertiary amines when used as part of a chemoenzymatic ox
282 ydroamination to furnish the enantioenriched tertiary amine, whereby enantioinduction occurs through
283 rovide perdeuterated primary, secondary, and tertiary amines, which are difficult to achieve via othe
285 onally and structurally diverse a-trialkyl-a-tertiary amines, which makes use of three readily availa
286 tion (HER), we studied the substitution of a tertiary amine with a softer pyridine group and the incl
287 nt yield from the reaction of a secondary or tertiary amine with o-iodoxybenzoic acid (IBX) or o-iodo
289 tive synthesis of sterically demanding alpha-tertiary amines with a tetrasubstituted carbon stereocen
290 the catalytic asymmetric alpha-acylation of tertiary amines with aldehydes facilitated by the combin
292 p(3))-H bonds adjacent to a nitrogen atom of tertiary amines with alkynyl bromides as radical alkynyl
293 ications are typically achieved by employing tertiary amines with catalytically active N, N-dimethyl
295 t cross-dehydrogenative coupling of aromatic tertiary amines with isocyanides and water leads to amid
298 ing substituents on nitrogen are superior to tertiary amines with sterically demanding substituents o
299 Mn-catalyzed reduction of tertiary amides to tertiary amines, with a useful scope, is demonstrated fo
300 metal-free and modular transformation forms tertiary amines, without structural constraint, via the