ライフサイエンスコーパス: tetracycline resistance

1 possible mutations leading to macrolide and tetracycline resistance.

2 the loss of the Lac+ phenotype or by loss of tetracycline resistance.

3 for ampicillin, vancomycin, teicoplanin, and tetracycline resistance.

4 nel, and to streptomycin, spectinomycin, and tetracycline resistance.

5 of gonorrhoea, but accelerated the spread of tetracycline resistance.

6 enerate a 500-bp deletion in tetW to abolish tetracycline resistance.

7 tetM accounted for 95.8% of tetracycline resistance.

8 ineered with a stochastic switch controlling tetracycline resistance.

9 RCDI patients, although donors primarily had tetracycline resistance.

10 ne residue result in loss of Tet(O)-mediated tetracycline resistance.

11 clindamycin resistance and, less frequently, tetracycline resistance.

12 lone in 2010 with associated clindamycin and tetracycline resistance.

13 nd identify residues critical for conferring tetracycline resistance.

14 ored the minus-strand origin while retaining tetracycline resistance.

15 a range of phenotypes that are unrelated to tetracycline resistance.

16 th tetracyclines was reduced by pre-existing tetracycline resistance.

17 a role of the interdomain loop in mediating tetracycline resistance.

18 f ribosomal protection proteins that mediate tetracycline resistance.

19 findings give insights into the mechanism of tetracycline resistance.

20 the tetracycline efflux protein, eliminated tetracycline resistance.

21 Overall, we observed a high rate of tetracycline resistance (89%) among colonizing GBS isola

22 for phenotypic expression of penicillin and tetracycline resistance afforded by the penB mutation.

23 Expression of tetracycline resistance allowed substantial enrichment o

24 ed with a significant increase in high-level tetracycline resistance and decreased susceptibility to

25 c interdomain loop of Tet(C) greatly reduces tetracycline resistance and efflux activity.

26 CTC11168 Nal(+), transconconjugants acquired tetracycline resistance and enhanced cytotoxicity toward

27 We find a high abundance of genes encoding tetracycline resistance and evidence that the tet(W) gen

28 ted relative to the reporter genes expressed tetracycline resistance and galactokinase activity in vi

29 adacycline molecule was designed to overcome tetracycline resistance and has broad-spectrum activity

30 CTn341 is 52 kb; it encodes tetracycline resistance and its transfer is induced by t

31 egulatory circuits in Escherichia coli, Tn10 tetracycline resistance and porin osmoregulation, the tr

32 Genes encoding tetracycline resistance and the integrase of Class 1 int

33 lates, we observed a significant increase in tetracycline resistance and TMP-SMX resistance, modest a

34 f the conjugative plasmid (which can mediate tetracycline resistance) and the beta-lactamase plasmid

35 cin resistance), class B tetA (which encodes tetracycline resistance), and an unidentified sulfametho

36 ce of dual resistance, and 84% prevalence of tetracycline resistance), and antibiotic consumption wit

37 The tet(S) gene is responsible for tetracycline resistance, and this gene is located on the

38 LDC activity but not tetracycline resistance appeared to be associated with t

39 s; (iii) while emergence of erythromycin and tetracycline resistance appears to largely occur indepen

40 cyclines potentiate selection for or against tetracycline resistance around localized sources of almo

41 Ribosome protection proteins (RPPs) confer tetracycline resistance by binding to the ribosome and c

42 e findings, the mechanism of Tet(O)-mediated tetracycline resistance can be explained in molecular de

43 Cells selected for tetracycline resistance, carried by the M. mycoides LC c

44 contact with plasma, plasmid transfer of the tetracycline resistance-carrying plasmid was also activa

45 model, a mutant of S. typhimurium carrying a tetracycline resistance cassette inserted in pefC was fo

46 Tetracycline resistance decreased from 1988 (23.4%) to 1

47 To make a comprehensive study of tetracycline resistance determinant distribution in the

48 phenicol acetyltransferase gene and the tetM tetracycline resistance determinant into Tn4001.

49 The presence of the tetracycline resistance determinant tet(M) in human clin

50 ococcus pseudintermedius (MRSP) carrying the tetracycline resistance determinant TetK.

51 nicida that has been associated with another tetracycline resistance determinant, tet(E).

52 The bacterial tetracycline-resistance determinant from Tn10 encodes a

53 er had contributed to the spread of specific tetracycline resistance determinants in these population

54 An analysis of serotype, distribution of tetracycline resistance determinants, and resistance pro

55 intermediate and is stimulated by coresident tetracycline resistance elements and low levels of tetra

56 se in ceftiofur resistance and a decrease in tetracycline resistance elements were observed among the

57 nd must be mobilized by resident chromosomal tetracycline-resistance elements.

58 Broad-spectrum PCR tests detected tetracycline resistance-encoding genes, tetM-tetO-tetS,

59 Transfer of vancomycin, ampicillin, and tetracycline resistance from C68 to an E. faecium recipi

60 e-stranded (ds) DNA sequences present in the tetracycline resistance gene (tetM), avoiding the need f

61 led to rapid expansion of both ceftiofur and tetracycline resistance gene copies/gram of feces.

62 e E. coli K-12 strain ORN151, containing the tetracycline resistance gene from Tn10 inserted in the f

63 Notably, tetracycline resistance gene tet(42) was present, indica

64 elevated MICs of tetracyclines harbored the tetracycline resistance gene tet(B) but none of the othe

65 Here, we examined the expression of tetracycline resistance gene tet(M) of a fluorescent Esc

66 ains ampicillin resistance gene blaTEM-1 and tetracycline resistance gene tetA, with UV254 doses up t

67 Ps were able to detect specific dsDNA of the tetracycline resistance gene tetM with high specificity

68 f a three-gene operon that also contains the tetracycline resistance gene tetQ.

69 gene of P. aeruginosa was replaced with the tetracycline resistance gene via allelic exchange.

70 acrolide efflux gene), and tetM (the class M tetracycline resistance gene).

71 resistance gene) and pACYC184 (harboring the tetracycline resistance gene).

72 he elimination of IPTG, the inclusion of the tetracycline resistance gene, and the high level of prot

73 ase, each carrying either an erythromycin or tetracycline resistance gene, and where multidrug-resist

74 ncrease expression of the divergent upstream tetracycline resistance gene, tetR.

75 acquisition of a Tn916 transposon carrying a tetracycline resistance gene, which has been stably inhe

76 s could correct a mutation in an antibiotic (tetracycline) resistance gene in a plasmid.

77 y true when the plasmid carries a functional tetracycline-resistance gene tetA, and is borne in a top

78 covering 13 distinct haplotypes for a tet(Q) tetracycline-resistance gene with >18,000x coverage and

79 can be selected by restoration of an intact tetracycline-resistance gene.

80 High abundances of tetracycline resistance genes (9.55 x 10(2) to 1.69 x 10

81 The highest relative abundance was tetracycline resistance genes (manures) and multidrug re

82 These genes were linked to tetracycline resistance genes and mobile genetic element

83 valence of beta-lactam, fluoroquinolone, and tetracycline resistance genes exists and is independent

84 ombinant Escherichia coli strains expressing tetracycline resistance genes from each mechanism (efflu

85 fate of plasmid DNA carrying ampicillin and tetracycline resistance genes in aged urine, including i

86 ment regimens on quantities of ceftiofur and tetracycline resistance genes in feedlot cattle.

87 A total of 384 ARGs were detected, with tetracycline resistance genes such as tetM and tetX bein

88 re screened for cephalosporin, quinolone and tetracycline resistance genes using PCR.

89 ted, five macrolide resistance genes and two tetracycline resistance genes were increased significant

90 Tetracycline resistance genes were most abundant in cont

91 Beta-lactamase and tetracycline resistance genes were the most prevalent (2

92 The concentration of ampicillin and tetracycline resistance genes, as measured with quantita

93 nd in 56% of isolates; 85.2% of isolates had tetracycline resistance genes.

94 that of the wild-type protein as assayed by tetracycline resistance in cells and by transport in mem

95 lticopy plasmid pAMalpha1 (9.75 kb) encoding tetracycline resistance in Enterococcus faecalis is know

96 including a deletion that is associated with tetracycline resistance in Helicobacter pylori.

97 Pre-existing tetracycline resistance in Neisseria gonorrhoeae limits

98 , their utility waned after the selection of tetracycline resistance in the pathogens against which t

99 al attenuation is responsible for control of tetracycline resistance in these other cases as well.

100 For example, tetracycline resistance increased from 3.7% in 2010 to 9

101 ivatives with transposon Tn916 (encoding for tetracycline resistance) insertions on the chromosome.

102 Regulation of Tn10-derived tetracycline resistance involves a repressor, TetR, and

103 imately 25 kb of ICEPdaSpa1 DNA, including a tetracycline resistance locus, is not present in SXT.

104 cycline against gonorrhea, and selection for tetracycline resistance may influence prevalence of mult

105 d sequences found in all samples belonged to tetracycline resistance mechanisms.

106 ), tet(A)) and ribosomal protection (tet(M)) tetracycline-resistance mechanisms and are active agains

107 a, including pathogens bearing both types of tetracycline-resistance mechanisms.

108 45 and mega, were negative for Tn1207.1, had tetracycline resistance mediated by tet(M), and containe

109 a significant increase in rate of high-level tetracycline resistance mediated by the tetM gene in the

110 In this study, the genetic support for the tetracycline resistance of E. faecium 664.1H1 was charac

111 the hydrophobic quinolone resistance and the tetracycline resistance of the mgrA mutant and that MgrA

112 omoter which consists of seven copies of the tetracycline resistance operator (tetO).

113 system utilizes the control elements of the tetracycline resistance operon encoded in TnlO of Escher

114 ression system using control elements of the tetracycline resistance operon has recently shown promis

115 ons of the system based on components of the tetracycline resistance operon, several strategies have

116 compassing the Tet repressor (TetR) from the tetracycline-resistance operon (tet from Escherichia col

117 The control elements of the tetracycline-resistance operon encoded in Tn10 of Escher

118 e by site-directed mutagenesis did not alter tetracycline resistance or efflux activity.

119 promoters that provided E. coli with higher tetracycline resistance over the native promoter when pl

120 Tetracycline resistance peaked at 25.8% in 1997 and decl

121 olecules to regulate conjugative transfer of tetracycline-resistance plasmid pCF10 in E. faecalis.

122 The tetracycline-resistance plasmid pCF10 represents a parad

123 rties of the cysteines in the pBR322-encoded tetracycline resistance protein have been examined.

124 d with the next even-numbered segment in the tetracycline resistance protein sequence.

125 Tetracycline resistance protein Tet(O), which protects t

126 le by generating a family of variants of the tetracycline resistance protein TetX2 and identified the

127 al membrane insertion elements in the pBR322 tetracycline resistance protein were identified by compa

128 sary for efficient membrane insertion of the tetracycline resistance protein.

129 RNA accommodation and prevents rescue by the tetracycline-resistance protein TetM.

130 y similar to proteins of the Tet(A) class of tetracycline resistance systems.

131 ini-Tn5 promoter reporter genes encoding for tetracycline resistance (tc(p-)) or luminescence (luxAB(

132 egrative and conjugative elements conferring tetracycline resistance (TcR).

133 tance (bs(r)) cassette linked to a bacterial tetracycline resistance (tet(r)) cassette.

134 These megaplasmids contained genes for tetracycline resistance [tet(O)], the Type IV secretion

135 ndem promoterless reporter genes that encode tetracycline resistance [tetA(Q)2] and galactokinase (ga

136 es in prostatic tissue encoding 16S rRNA and tetracycline resistance (tetM-tetO-tetS); (ii) controlle

137 In Brazil, a high level of tetracycline resistance (TetR) is mainly associated with

138 point regression to investigate trends in NG-tetracycline resistance (tetR), 2017-2024 and, among sex

139 by mutation of a Tn1O element, which encodes tetracycline resistance (Tetr), to tetracycline sensitiv

140 In addition to the genes involved in tetracycline resistance, the loop region of the composit

141 carries a tetO gene, conjugative transfer of tetracycline resistance to another strain of C. jejuni c

142 the repeats restores an intact tetA gene and tetracycline resistance to the cell.

143 Klebsiella pneumoniae, and a region encoding tetracycline resistance transferred through recombinatio

144 xacin resistance in 30/155 (19%) persons; no tetracycline resistance was documented.

145 mpared with 12% human plasmids); conversely, tetracycline resistance was enriched in livestock vs hum

146 e MG 16S rRNA which could be associated with tetracycline resistance was observed in 12.5% of specime

147 MG 16S rRNA, which could be associated with tetracycline resistance, was observed in 12.5% of specim

148 city of > or = 98% for all components except tetracycline resistance, which had a sensitivity of 94.7

149 of clindamycin resistance but lower rates of tetracycline resistance, while the South had notably hig

150 effectiveness (defined as 84% prevalence of tetracycline resistance) within the 20-year period, but