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1                                 We highlight the importance of a coordinated and consistent data coll
2                 These observations highlight the importance of a healthy microcirculation and suggest
3                              Here, we reveal the importance of a mutation's collateral fitness effect
4 ratory syndrome coronavirus, which highlight the importance of a robust safety and efficacy profile,
5                      The images demonstrated the importance of accurate head positioning, because a s
6                         This case highlights the importance of accurate identification and treatment
7 eristics among the three species demonstrate the importance of accurate species identification for an
8 ermore, size has been an impediment owing to the importance of achieving nanoscale (ca. 100 nm) dimen
9                        Overall, we highlight the importance of acute aerobic exercise for children wi
10                                              The importance of affect processing to human behavior ha
11                                      Despite the importance of AKT overactivation in tumor progressio
12 ts that previous studies have underestimated the importance of altered P supply on aboveground plant
13                 This paper thus demonstrates the importance of an intact alcove in forming and stabil
14 igenic repertoires in human autoimmunity and the importance of antigen discovery for improved underst
15                This contribution establishes the importance of applying SOMC to MOF chemistry to get
16 the value of receptor-selective agonists and the importance of appropriately interpreting data in the
17 framework presented in this study reinforces the importance of assessing dog ownership well-being out
18                    These findings underscore the importance of assessing histologic CRC subtypes inde
19                        Our results highlight the importance of assessing intact genital tissue sample
20 l binding partner capicua (CIC) demonstrates the importance of ATXN1 native interactions for correct
21         Risk factors we identified highlight the importance of avoiding dehydration and performing cl
22  than BMI at older ages, and they underscore the importance of avoiding excess weight gain before mid
23       Taken together, these results underlie the importance of balanced vaccine-induced activating ve
24                        These data underscore the importance of beta-lactams for SaB, including consid
25 tions on healthcare reform while recognizing the importance of biomedical research, providers, and he
26                       Our findings highlight the importance of both Calpha and Cbeta subunits of PKA
27  mug/m(3)) to PM(2.5) in Delhi, highlighting the importance of both external transport and local emis
28 ofessionals' struggle to talk about disgust; the importance of boundaries: boundary breaching and bou
29 nd several years after exposure demonstrates the importance of broad differential diagnostics in the
30             This formal genetic evidence for the importance of Btnl heteromers also applied to the st
31                    These results highlighted the importance of cannabinoids testing of food products
32 d associated metrics for success underscores the importance of cardiovascular health and cardiovascul
33  survival, immune evasion, and escape, while the importance of catabolism of host-derived proteins an
34                         Here, we interrogate the importance of CenDNA in centromere specification by
35                               We demonstrate the importance of chromosome-scale phased assemblies for
36                         The study highlights the importance of chronic glucose exposure on cell pheno
37 ponses lie under circadian control; however, the importance of circadian mechanisms in the underlying
38                               However, given the importance of climatic water balance on SIC accumula
39                         This case highlights the importance of close coordination between clinicians
40                             We shed light on the importance of compartmentalization to preserve the e
41                                              The importance of complex traits in biology and medicine
42 dictability as a reality check and considers the importance of computation in data collection/storage
43 cture for ICU interprofessional team rounds; the importance of conducting rounds at patients' bedside
44                      These results highlight the importance of considering 3D cultures to model host-
45                          Our results suggest the importance of considering both natural and human fac
46                       Our findings highlight the importance of considering lineage-specific TEs in st
47                        Overall, we emphasize the importance of considering memories not as static ent
48                     These findings highlight the importance of considering multiple maternal features
49 f SCAD has increased over time, highlighting the importance of considering SCAD among patients with a
50                      These results highlight the importance of considering study design and medical h
51                       Our findings highlight the importance of considering these structures, as regio
52 ed to update vaccines for swine in Chile and the importance of continued surveillance to determine th
53                         These data highlight the importance of continuous norovirus surveillance and
54                     These findings underline the importance of continuously challenging patients and
55         The aim of this review is to explore the importance of converting thin phenotype into a thick
56                                              The importance of core fucosylation can be seen in the c
57                     These results illustrate the importance of coupling controlled reaction environme
58 nterparts by at least fivefold, highlighting the importance of CRISPR-mediated defence against plasmi
59 -dependent Cav-1 phosphorylation, indicating the importance of CSD in the interaction.
60 build a wide community for a genome project, the importance of data management, and how to make the d
61                        This study underlines the importance of DC-mediated priming in identifying nov
62 aviour and life history, while demonstrating the importance of demographic-dependent selection in sha
63  specific clinical features; this highlights the importance of developing individualized approaches t
64                                              The importance of dietary acid load (DAL) in the pathoge
65                    Our experiments highlight the importance of different communication relayed among
66                 Recent studies have explored the importance of different forms of extracellular PDL1,
67 nd theoretical models of addiction emphasize the importance of different memory systems for understan
68                                              The importance of different nucleotides in the 5' stem-l
69 icrostimulation and lesions, have documented the importance of direction-selective activity in the ar
70 tina in Parkinson disease (PD) pathology and the importance of dopaminergic cells in this tissue, we
71                                              The importance of dried blood spots (DBSs) has increased
72                                              The importance of dysregulated CD86 expression in Tet2-
73 w into sections based on the target analyte, the importance of each analyte and then the reported IDA
74 ronal culture cluster networks by estimating the importance of each network node and their informatio
75 score (PIS) was further provided to quantify the importance of each pathway.
76                         Our study highlights the importance of early diagnosis and treatment of cardi
77 use model of maternal obesity to investigate the importance of early life ER stress in the nutritiona
78 ranscriptional profiles of PBMC, reinforcing the importance of early TI.
79 consideration for applied phage biology, and the importance of ecology in evolution of phage resistan
80                               Here we reveal the importance of electrostatic interactions for the act
81                        This work underscores the importance of employing true null mutants in genetic
82        Our study is the first to demonstrate the importance of energy compensation to an animal's rep
83 sh environments and HMP patterns may reflect the importance of environmental filtering in shaping com
84 AP were confirmed with this assay, including the importance of enzyme and substrate concentrations, c
85                              We also discuss the importance of eradicating NPM1-mutated clones to ach
86                         This work highlights the importance of examining NPs in their post-use phases
87 ever, increased resistance to ACT highlights the importance of finding new drugs.
88 hanges in the land carbon sink and highlight the importance of fire management in climate mitigation.
89 ted to disrupt embryo development; emphasize the importance of following established nomenclature gui
90                        Our results underline the importance of following up findings from genome-wide
91                       Our findings highlight the importance of formulations that conform to the ocula
92 In this context, this review discusses about the importance of four fruits species representative of
93             Together, our studies illustrate the importance of functionally interrogating diverse tum
94  There have been many recent reviews on: (i) the importance of g(m) for accurately modelling net rate
95                           Our data emphasize the importance of gene expression regulation through the
96 ations with relevant exposures and highlight the importance of gene-environment interactions in shapi
97 ease subtype in the literature and highlight the importance of genetic testing in the relevant clinic
98                                  Considering the importance of genomics in the development of any cro
99                               This underlies the importance of glia-matrix communication for structur
100            Despite increasing recognition of the importance of GM-CSF in autoimmune disease, it remai
101                        These findings stress the importance of governing urban land development as a
102 and other air pollutant emissions highlights the importance of ground-level NH(3) emissions from comp
103        Collectively, these results highlight the importance of growth factors of the insulin family d
104 n the RAS+B system, potentially highlighting the importance of heterotrophy.
105                           These results show the importance of high ATP in DnaA oligomerization and i
106                   In particular, we identify the importance of high densities of coordination bonds a
107 Nonfunctional SSD mutants allowed us to test the importance of Hmg2 quaternary structure in malloster
108   Moreover, increasing island area increased the importance of homogeneous selection, but reduced the
109  too small to admit either guest, signalling the importance of host dynamics for guest entrance to an
110 6p22.1 and 18q22.2) for SCCHN risk highlight the importance of human leukocyte antigen loci for oroph
111 result of protein stabilization, emphasizing the importance of identification of the machinery that r
112 ggest directions for future research, noting the importance of identifying the operative dimensions o
113                      These results reinforce the importance of IL-13 in airway pathobiology and sugge
114 is dynamic during the CO(2)RR, and emphasize the importance of in situ characterization to understand
115                                        Given the importance of inappropriate NOTCH1 signalling in T-c
116                         This study indicates the importance of including data about the habitat modif
117 y for land use change studies and highlights the importance of including land-atmosphere coupling, wh
118 erse aquatic vertebrate fauna and highlights the importance of including multiple water types in cons
119                      Nevertheless, resolving the importance of indirect and environmental transmissio
120 hts into the development of NKTCL by showing the importance of inflammation and immune regulation thr
121 ells and p24 production in RM and underscore the importance of inflammatory cytokines in mucosal HIV
122 lammation, and oxidative stress, underlining the importance of inflammatory mediators in the patholog
123                        These results support the importance of influenza vaccination in older adults,
124                             This model shows the importance of initial asymmetry and its reinforcemen
125                        Our study underscores the importance of integrating evolutionary responses in
126 s about insect conservation and highlighting the importance of integrative approaches to pesticide us
127 ularly in tumour subtyping-have demonstrated the importance of integrative clustering techniques for
128                                        Given the importance of integrin-mediated cell-matrix adhesion
129                                      Despite the importance of interfacial proteins, comparatively li
130                             Here, we discuss the importance of interpretable ML, different strategies
131 ances in microbiome science have highlighted the importance of intestinal microbes in human physiolog
132                           Our study suggests the importance of investigating biological and clinical
133                                Consequently, the importance of isoform-specific functions of GSK3 in
134 r substrate K(+) and Cl(-) ions, demonstrate the importance of key coordinating residues for transpor
135 dditional sensitivity analyses to understand the importance of key parameters, such as the electricit
136                         These data highlight the importance of knowing which specific peptidase(s) co
137                                        Given the importance of Lepidoptera to food webs and ecosystem
138                     These results underscore the importance of ligand-independent TNFR1 dimerization
139 In conclusion, our study clearly illustrates the importance of local community assembly processes in
140 vision rates, an observation that highlights the importance of loss processes in dictating the evolut
141 temic sclerosis in Han Chinese and suggested the importance of LRP2BP in systemic sclerosis pathogene
142                                              The importance of maintaining COC should be emphasized t
143                              This highlights the importance of maintaining effective surveillance sys
144                 Clinicians frequently stress the importance of maintaining good oral health for multi
145              Long-standing evidence supports the importance of maintaining healthy populations of mic
146                        Our results highlight the importance of managing the increasing homogenization
147 ical stretching and bending of membranes and the importance of membrane deformations in the analysis
148                                   We discuss the importance of mitigating pan-continental spread in l
149                        This study highlights the importance of mitochondrial aconitase activity in th
150 ion is presumably maintained by coevolution, the importance of mitonuclear coevolution in key biologi
151            For the first time, we discovered the importance of multivalency in the PML II-ICP0 intera
152               In this study, we investigated the importance of Musashi proteins in the development an
153                       Our findings highlight the importance of N-linked glycosylation of ACLP for its
154                        This study highlights the importance of NAMPT-mediated NAD(+) biosynthesis in
155                      These results highlight the importance of natural patterns of facial behaviour i
156    Thus, we adopt a long-term perspective on the importance of nearby neighbors during a period when
157 tivities were mostly unaffected, emphasising the importance of negative selection to effect enzyme sp
158  provides insights into the role of defects, the importance of neglected material-quality control, an
159                                  demonstrate the importance of neutrophil extracellular traps in helm
160                 These data shed new light on the importance of neutrophils in AMI to Y. pestis and ma
161                              We also discuss the importance of NMD for gene editing and tumor evoluti
162                              This highlights the importance of NMS for DBS outcomes assessments.
163  rapid and extensive dark oxidation elevates the importance of nocturnal chemistry and biomass burnin
164 ystems, giving a few examples to demonstrate the importance of nonequilibrium thermodynamics for unde
165 med the first comprehensive investigation of the importance of NTR nucleotides in the context of the
166                       Our findings emphasize the importance of NUCB1 as an essential component of MMP
167         Although our findings do not exclude the importance of other signaling differences between BB
168        Collectively, these results highlight the importance of PARP family members and ADPRylation in
169                                It highlights the importance of pathologist/machine interactions for t
170                                    To assess the importance of pathways for aromatic compound oxidati
171 de of weight regain after RYGB, highlighting the importance of patient-level factors.
172            Together, these results highlight the importance of PD-1 agonistic treatment in allergic a
173  etiology of complex diseases and highlights the importance of performing GWAS in non-European popula
174            Together, these studies highlight the importance of peripheral nerves as a new therapeutic
175              Our results therefore highlight the importance of peripheral vision during trans-saccadi
176                     In vitro studies support the importance of Pfn1 in proliferation and migration of
177 m of early childhood asthma and demonstrates the importance of phenotype-specificity for discovery of
178                    These studies demonstrate the importance of phospholemman phosphorylation in the r
179                           These data support the importance of physical coupling of histone modificat
180  contributes to an increasing recognition of the importance of physico-chemical properties in determi
181                    While not underestimating the importance of plastics in the prevention of COVID-19
182         Despite long-standing recognition of the importance of precipitation amount and variability f
183 ell-encapsulation strategies by highlighting the importance of preconditioning or priming the capacit
184 ghts for rational vaccine design, indicating the importance of preserving both the global structural
185                      These results highlight the importance of prompt and regular monitoring of cardi
186  pathological responses to ROS and highlight the importance of protein kinase regulation through mult
187  induced PIP2 clustering in MACA, indicating the importance of protein multimerization.
188 ynthesis and protein translation, suggesting the importance of protein synthesis during the larval im
189           Further investigation demonstrated the importance of protein targets for ELISA.
190 dults' experience of arthritis pain, realize the importance of providers' support on patients' adapta
191                         Our study highlights the importance of pyrimidine salvage during the earliest
192       Error-prone PCR mutagenesis reinforced the importance of R225 substitutions, found in 100% of s
193              The Summit attendees identified the importance of raising awareness among critical care
194                       This work demonstrates the importance of recognizing the interplay between sex
195  and 'avoiding overthinking' in referring to the importance of relying less on high-level explicit st
196                       Our results underscore the importance of replication and multiscale approaches
197                          Recent events bring the importance of respiratory health to the forefront of
198 fDNA for lung cancer screening and highlight the importance of risk-matching cases and controls in cf
199 to advance and solidify our comprehension of the importance of root exudates in ecosystem response to
200  a clonal C. auris population and highlights the importance of routine high-resolution genomic survei
201 ber of reports in the literature documenting the importance of S-acylation in human physiology and di
202 gorous inspection of food contact materials, the importance of sample preparation for nontarget scree
203              Our results, however, highlight the importance of sampling and the use of a plurality of
204 on the competing aphid phenotypes highlights the importance of scenario testing when considering bioc
205                     These findings emphasize the importance of screening patients for preoperative op
206                 In this Review, we highlight the importance of single-particle spectroscopy in reveal
207                Building upon data suggesting the importance of sleep in learning and memory, we teste
208  in fundamental SMC processes and indicating the importance of smooth muscle response to vascular str
209     However, extremely little is known about the importance of social relationships between neighbour
210 istribution of individuals have demonstrated the importance of spatial organisation for individual fi
211                   Our results also highlight the importance of spatially explicit season-specific oil
212                         Greater awareness of the importance of spirituality among clinicians and nurs
213                                        While the importance of staff-resident (dyadic) interactions d
214 model selection provided strong evidence for the importance of status-specific differences in resourc
215                         We have investigated the importance of stereochemistry, the effect of N-termi
216 kers, and men who have sex with men, include the importance of strategies for maintaining persistent
217                            They further show the importance of studies combining physiological and gr
218                                              The importance of studying acute infection was highlight
219                        This study highlights the importance of studying both group-level behaviours a
220 tribute to these associations and underscore the importance of studying such factors, particularly in
221 ine and open ocean mean values and highlight the importance of subglacial aluminosilicate mineral wea
222 tially lower incidences of ESLD, underlining the importance of successful HCV treatment for reducing
223                         This work highlights the importance of sulfonamide precursors in contributing
224                             We also examined the importance of superoxide in the mediating pathways a
225                                              The importance of supramolecular interactions in COFs to
226                                              The importance of surface coverage effects was highlight
227 o host performance, these findings emphasize the importance of symbiont community diversity and stoch
228         In this review article, we highlight the importance of tailoring nano-DDS to address bacterio
229                                      Despite the importance of TBR for swallowing performance, the me
230 ter-soluble quinone analogues, demonstrating the importance of testing compounds under physiologicall
231                       Our study demonstrates the importance of the adaptability that is enabled by st
232                    Researchers now recognize the importance of the coral microbiome, but they often o
233                 Our findings further support the importance of the early life window for microbiota-e
234 ng roles in osteoclast biology, highlighting the importance of the HIF pathway as a potential therape
235                      Our findings underscore the importance of the interfacial oxygen vacancy migrati
236 r, these new WNK1 genetic variants highlight the importance of the KS-WNK1 isoform abundance on potas
237 about the receptor distal N-termini, despite the importance of the latter in signaling, regulation, a
238     Whereas animal studies have demonstrated the importance of the link between perinatal cytokines a
239 se in DIAAS (from 117% to 97%), highlighting the importance of the matrix effect on nutritional prote
240  in neurodegenerative disease and underscore the importance of the mitochondrial unfolded protein res
241 MNIST dataset, respectively, suggesting that the importance of the network structure increases as the
242  of CLN1 disease pathogenesis, and highlight the importance of the neuroimmune response.
243 fficient than TBP and ExBox(+4) , confirming the importance of the newly formed excited-state manifol
244                                      Despite the importance of the Ngandong fossils, the relationship
245 pinning of attention in aging and underscore the importance of the noradrenergic system in late-life
246                                Understanding the importance of the oceanic background state, local an
247 erived heptapeptides and furthermore discern the importance of the OxyE enzyme in maintaining effecti
248                                              The importance of the placenta in supporting mammalian d
249                        The results highlight the importance of the RadD protein for general chromosom
250 chial flow-mediated dilatation and highlight the importance of the simultaneous consideration of nitr
251 econdary degeneration of cones, highlighting the importance of the spatial and temporal location of k
252                                              The importance of the sulfate groups was delineated by u
253                        Our results highlight the importance of the twilight zone for white sharks and
254 C1-activated lung mesenchyme and establishes the importance of the WNT signaling pathway in the mTORC
255                             This highlighted the importance of the zeolite's mechanical strength for
256    Taken together, these findings underscore the importance of their function as an evolutionary adva
257 gnostic biomarkers for patients with IBD and the importance of their validation in large, independent
258 oblast lineage cells in order to investigate the importance of these cells as a source for loading-in
259 A-binding and tetramerization domains cement the importance of these domains in tumor suppression.
260                                              The importance of these in-silico findings is validated
261                                              The importance of these molecules stems from their antim
262                                              The importance of these observations is 3-fold.
263 ere, we discuss recent evidence highlighting the importance of these specialized plasma membrane doma
264      In comparison, much less is known about the importance of these two arms of the defence for the
265 pecific transketolase genes (tktAB) suggests the importance of this enzyme for xylose metabolism.
266                                              The importance of this gene in the A2780TR cell line was
267 ance in a semantic judgment task, indicating the importance of this higher-order topological feature
268                                      Despite the importance of this mechanism of glycinergic dis-inhi
269  DNA bending by APE1, providing evidence for the importance of this mechanism.
270 y the hematite-Fe(2+) redox couple to assess the importance of this process for the attenuation and r
271 chondrial degradation (mitophagy) reaffirmed the importance of this process in PD aetiology.
272          Despite previous research entailing the importance of this signaling pathway and the organis
273 with clinical findings, our work underscores the importance of this variant in viral spread and its i
274                                    We assess the importance of Thomas rotation in the calculation of
275  neuronal TRPV4-associated Ca(2+) responses, the importance of tightly regulated Ca(2+) dynamics for
276                   The data further highlight the importance of tightly regulated communication betwee
277 of PER-bound TIM by mass spectrometry, given the importance of TIM as a modulator of PER function in
278 pplied earlier than recommended, emphasizing the importance of timely application.
279 ores time and timing among G-E transactions: The importance of timing and timescales in plasticity an
280                                              The importance of tissue damage in the pathophysiology o
281 ng previous assumptions but also reinforcing the importance of tissue Na(+) excess, are both mechanis
282                      These results highlight the importance of training residents in performing MIGS
283                     Thus, our data highlight the importance of transcription termination and antiterm
284  IL-4 anti-inflammatory stimulation revealed the importance of Trem2 in driving a number of the genes
285 s whilst ensuring patient safety, we discuss the importance of triage, information gathering, symptom
286     Recent empirical studies have documented the importance of tropical mountainous rivers on global
287            Together, this study demonstrates the importance of UDP-GalNAcA in the pathobiology of A.
288                        Our results highlight the importance of understanding how different species re
289 as in autoimmunity and old age, highlighting the importance of understanding their role in immunity.
290                                 We highlight the importance of understanding, and accounting for both
291 n profiles of pigmented corns, and emphasise the importance of using acidified solutions for the extr
292                        Our results highlight the importance of using environmentally representative c
293 proaching leads to desolvation and increases the importance of van der Waals interactions.
294 rtance of homogeneous selection, but reduced the importance of variable selection, for soil bacterial
295 and genes across plant habitats has revealed the importance of various ecological and evolutionary fo
296  of IAV on multiple infection and underscore the importance of virus-virus interactions in IAV infect
297 ter-membrane organisation and communication, the importance of which is becoming increasingly apparen
298                    These findings underscore the importance of within-subject controls for DREADD act
299  ubiquitin ligase complex have shed light on the importance of WNK's cellular degradation on renal io
300  subsequent IDSA task forces have emphasized the importance of women, and other unrepresented minorit

 
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