ライフサイエンスコーパス: the paucity of

1 Nevertheless, the paucity of 3'-sequencing data in this species preclu

2 genes remain uncharacterized, mainly due to the paucity of a nonpolar gene inactivation system.

3 Thus, the paucity of activated CD103(+) DCs in tumors limits c

4 (CRPC) has been challenging because of both the paucity of adequate frozen tissues and a lack of int

5 Owing to the paucity of alimentary enzymes encoded by the human g

6 The mechanism is unknown in part because of the paucity of animal models displaying this feature of

7 The paucity of animal models exhibiting full pathology o

8 mpediment to novel drug development has been the paucity of animal models that accurately reflect sym

9 Because of the paucity of animal models that directly investigate t

10 major limitation in HNSCC research has been the paucity of animal models to test the validity of cur

11 adhesion biology is limited, which explains the paucity of anti-adhesion treatments.

12 Given the paucity of anti-VL drugs and the looming threat of r

13 n but is limited by the quality of fixation, the paucity of antibodies and the inaccessibility of ant

14 ease is a challenging pursuit, hallmarked by the paucity of antiviral agents currently prescribed.

15 s system remains ambiguous, partially due to the paucity of appropriate investigative methods.

16 cans remain largely unknown, mainly owing to the paucity of appropriate probing techniques.

17 Due to the paucity of Aspergillus genomic resources 10 years ag

18 crease in the popularity of e-cigarettes and the paucity of associated longitudinal health-related da

19 Due to the paucity of atmospheric organic N data, the largest u

20 ing the spatial pattern of disease spread is the paucity of available data together with the challeng

21 Given the paucity of available data, the heterogeneity of stud

22 that has not been fully exploited because of the paucity of available genetic tools.

23 The paucity of available hearts for transplantation mean

24 l fitting remain a practical challenge given the paucity of available software to evaluate performanc

25 ably, the most unexpected aspect of LTTRs is the paucity of available structural information.

26 We propose that largely due to the paucity of biomarkers for primary psychiatric disord

27 The paucity of biomarkers to predict prostate tumor biol

28 The paucity of bone repair in inflammatory diseases such

29 The paucity of boron-containing heteroalkene complexes p

30 The paucity of both cell types has hampered molecular an

31 controls of river primary production due to the paucity of both long-term studies and of depositiona

32 the extent that ecology has a role, however, the paucity of bottom-heavy clades radiating in the imme

33 Given the paucity of case material, we speculated that this is

34 CD4(+) target cells in the mucosa, and (iii) the paucity of CCR5(+) CD4(+) target cells in infant and

35 tially restored function but did not correct the paucity of CD56(bright) cells.

36 ing and regenerative medicine are limited by the paucity of cell types that can be generated in the l

37 limitations to Treg clinical application are the paucity of cells and limited knowledge of the mechan

38 tissue injuries have limited repair, due to the paucity of cells at the wound site.

39 This is partly due to the paucity of chemical techniques that can autonomously

40 The paucity of chemotherapeutic agents that are effectiv

41 The paucity of cis associations with transcripts was con

42 ck of a standard definition for HFrecEF, and the paucity of clinical data with respect to the natural

43 One difficulty is the paucity of clinical grade manufacturing platforms to

44 ty of evidence that is less than high due to the paucity of clinical trials regarding screening, mana

45 e antimetastatic agents has been hampered by the paucity of clinically relevant preclinical models of

46 ve nature of the electron-rich aromatics and the paucity of commercial sources pose some obstacles to

47 reversible reaction directionality is due to the paucity of compartment-specific quantitative metabol

48 evolved through our studies is notable given the paucity of competing reaction pathways observed in t

49 Given the paucity of compounds that reduce hyperexcitability a

50 argets in mucosal melanoma is limited due to the paucity of comprehensive mutation data on this rare

51 annual outbreaks of infectious diseases, but the paucity of data about travel behavior and population

52 mptoms (SUNA) remains challenging in view of the paucity of data and evidence-based treatment recomme

53 Because of the paucity of data for FGIDs, we included data for non-

54 Key limitations related to the paucity of data from low- and middle-income countrie

55 rimate model in neurodevelopmental research, the paucity of data from more closely related great apes

56 oves clinical outcomes is unclear because of the paucity of data from randomised placebo-controlled t

57 derstanding of these processes is limited by the paucity of data from undisturbed tropical ecosystems

58 cardiac remodeling is derived from men, with the paucity of data from women representing an important

59 een studied rigorously, which contributes to the paucity of data in children.

60 SC-dependent functions has been hindered by the paucity of data on innervation patterns to specific

61 Given the paucity of data on motility and the absence of direc

62 unding by indication in the African studies, the paucity of data on potential confounders, the limite

63 Considering the paucity of data on sex differences and the knowledge

64 Given the paucity of data on this topic, the optimal surgical

65 The paucity of data prevented detailed subgroup analysis

66 The paucity of data regarding the extent of hepatitis de

67 active compounds from soy-based formulas and the paucity of data regarding their bioavailability, the

68 pproach to preventing infections in light of the paucity of data specific to this treatment modality.

69 Limitations include the paucity of data to individually assess quality of ca

70 Acknowledging the paucity of data to support widespread adoption of su

71 l single-institution studies, and because of the paucity of data, the optimal treatment for male brea

72 Recognizing the paucity of data, we advocate participation in clinic

73 on quotient remains poorly understood due to the paucity of described endocranial casts.

74 remains intensely debated, owing in part to the paucity of detailed regional datasets and the comple

75 This likely contributes to the paucity of detectable zoonotic cynomolgi malaria.

76 However, due to the paucity of diagnostic facilities in typhoid-endemic

77 ehind few material remains, is challenged by the paucity of direct evidence demonstrating who was inv

78 erapeutics have been hampered for decades by the paucity of disease models that integrate molecular a

79 However, the paucity of distance restraints >5 A, traditionally d

80 which can be prohibitive for many students, the paucity of diverse mentors who share common experien

81 The paucity of diversity, of women and minorities, parti

82 which have unfortunately been limited due to the paucity of donor liver tissues.

83 y the need for chronic immunosuppression and the paucity of donor tissue.

84 because of its transient effect on disease, the paucity of donors, and the requirement for strong im

85 Given the paucity of druggable mutations in high-risk neurobla

86 d unrecognized phenotypic heterogeneity, and the paucity of early ARDS lung tissue limit some applica

87 Enterococcus (VRE) infections is limited by the paucity of effective antibiotics.

88 To address the paucity of effective new therapies, we undertook a h

89 Rationale: Given the paucity of effective treatments for idiopathic pulmo

90 Given the paucity of effective, non-myelosuppressive therapies

91 The paucity of empirical data is a limitation of these f

92 s in different internal organs is to address the paucity of empirical data on thanatomicrobiomic succ

93 oke care delivery remain unanswered owing to the paucity of empirical data, we are convinced that str

94 Does the paucity of empirical evidence of sympatric speciatio

95 mechanistically and employed synthetically, the paucity of enantioselective variants is striking.

96 The paucity of enzymes that efficiently deconstruct plan

97 mechanism of quality control-induced ERAD is the paucity of ERAD substrates being dislocated and dete

98 s in rare cancers remains challenging due to the paucity of established models to perform preclinical

99 opmental heterogeneity of DN1 thymocytes and the paucity of ETPs.

100 One barrier to widespread adoption is the paucity of evidence for improved outcomes in patient

101 and avoid the use of these agents because of the paucity of evidence in the treatment of cancer-assoc

102 Given the paucity of evidence to accurately classify each vari

103 in critically ill patients is common despite the paucity of evidence validating its accuracy in criti

104 Two recent reports document the paucity of evidence-based data regarding the effecti

105 The paucity of examples has served as a significant hind

106 Due to the paucity of experimental animal models, little is kno

107 ediate are limited in applicability owing to the paucity of experimental knowledge about its geometri

108 e been refractory to characterization due to the paucity of experimental methods able to probe the mo

109 n on identifying precise mechanisms has been the paucity of experimental systems in which actin funct

110 s from different research groups, leading to the paucity of extrapolations of experimental findings i

111 ntion molecule CCR7, possibly accounting for the paucity of F CTL.

112 war statements) remain unknown, however, and the paucity of field data precludes our ability to test

113 The paucity of field observations on SOC under ISA (SOCI

114 is achieved is unknown but essential, given the paucity of foreign pMHC ligands relative to the ubiq

115 e degeneration of SGNs have been hampered by the paucity of functional data on the role K(v)7 channel

116 f neurogenesis from GBCs has been impeded by the paucity of GBC-specific markers.

117 The paucity of generalizable typhoid epidemiological dat

118 Unfortunately, the paucity of genetic data from many of these subtypes

119 The paucity of genome-level data for Apocynaceae preclud

120 This has proved challenging due to the paucity of genomic data and genetic tools available

121 c and health impact studies are inhibited by the paucity of global, long-term measurements of the che

122 These questions are driven by the paucity of hand fossils in the hominin fossil record

123 The paucity of hepatitis B virus (HBV) DNA measurement i

124 The paucity of high resolution spatial-temporal influenz

125 The paucity of high-level evidence and the conflicting n

126 Given the paucity of high-quality data before 2001, we relied

127 Given the paucity of high-quality data, it is difficult to def

128 We note the paucity of high-quality evidence for interventions i

129 The guidelines reveal the paucity of high-quality evidence, highlighting the n

130 pre-and-postoperative interventions reflects the paucity of high-quality evidence, suggesting a need

131 the care of transgender women is limited by the paucity of high-quality research, and long-term long

132 On the basis of the paucity of high-quality, consistent evidence, there

133 d, which for many years was characterized by the paucity of high-resolution structures.

134 in D. radiodurans Mn(2+) speciation, despite the paucity of holo-SodA.

135 The paucity of homologous character data across disparat

136 ns undiscovered, at least in part because of the paucity of HSCs and the modest ex vivo expansion of

137 The paucity of human donors limits broadened application

138 We confirm the paucity of humoral response in patients with CM-FPIE

139 We explore the reasons for the paucity of I(2) complexes and propose candidates for

140 ular pathology and cognitive impairment, and the paucity of identifiable tractable treatment targets.

141 However, the paucity of identified epitopes to this virus has lim

142 L-13Ralpha1 on neonatal Th1 cells was due to the paucity of IL-12 in the neonatal environment.

143 tudy of these diseases is difficult owing to the paucity of imaging techniques with the sensitivity a

144 astrointestinal tract research is limited by the paucity of in vitro intestinal cell models that reca

145 Our knowledge of HSC biology is limited by the paucity of in vivo data.

146 is hypothesis has remained unverified due to the paucity of in vivo studies of neuronal mechanical be

147 ins a longstanding challenge, in part due to the paucity of incisive experimental probes of electrost

148 mmalian olfactory coding has been impeded by the paucity of information about the odorant receptors (

149 s of developing and adult olfactory systems, the paucity of information available on the aged olfacto

150 broken during chromatographic analysis or to the paucity of information obtained from the benchmark m

151 The paucity of information on growth, mortality, and fis

152 Among them is the paucity of information on maize's early morphologica

153 and providers' skills is highlighted, as is the paucity of information on maternity waiting homes an

154 n to subjects with HHV6 has been hindered by the paucity of information on targets of cellular immuni

155 Our work also highlights the paucity of information on the processes that result

156 y of performing such studies in bacteria and the paucity of information that exists regarding ion tra

157 However, the paucity of inhibitors has precluded the clinical val

158 nline solves the problem of data collection, the paucity of internet access among low-income and mino

159 Thus, the paucity of knowledge about the epidemiology, virulen

160 and eye development is not known because of the paucity of knowledge about the growth of a key optic

161 al and aquatic ecosystems, thus highlighting the paucity of knowledge of the origins and potential bi

162 ogeneous mutations present in all humans and the paucity of known functional variants in more than 90

163 ons for brain health, especially considering the paucity of known protective factors for age-related

164 iven the lack of effective T1D therapies and the paucity of known side effects of PAHSAs, this lipid

165 ling pathways, however, has been hampered by the paucity of known substrates.

166 terrestrial net primary productivity due to the paucity of land plants, but our knowledge of these c

167 combat bacterial drug resistance increases, the paucity of leads resulting from target-based antibac

168 This high lethality combined with the paucity of licensed medical countermeasures makes EB

169 Given the paucity of literature on the subject good quality of

170 The paucity of longitudinal, serial high-resolution imag

171 This is likely because of the paucity of markers expressed by pericytes and the ab

172 embryonal arterial cells undergoing EHT and the paucity of markers to enrich for hemogenic endotheli

173 ynamic processes in vivo is difficult due to the paucity of methods capable of direct measurements.

174 However, it is often limited by the paucity of methods for precise genome manipulation.

175 ture during chemical reactions is limited by the paucity of methods for studying catalytic ensembles

176 The paucity of micro-exons (</= 51 nt) suggests that the

177 A gap identified by this review is the paucity of minimally-invasive methods for investigat

178 otor learning is limited, in part because of the paucity of model systems with a tractable learned be

179 The greatest diagnostic hurdle in PGD is the paucity of molecular material in the single embryoni

180 anomas and other tumour types) is limited by the paucity of mouse models for live imaging of distal p

181 e to understanding the pathogenesis of WT is the paucity of mouse models that recapitulate its featur

182 The paucity of multiple comparison corrections in ophtha

183 The paucity of murine memory B cell markers has been a s

184 The paucity of new antibacterial drugs is evident, and t

185 of the limitations of present treatments and the paucity of new drugs in the pipeline, infection cont

186 cess of this model reflects both "necessity"-the paucity of new therapies introduced through industry

187 Given the paucity of observations in the Arctic, models are us

188 ication Event (GOBE) is currently limited by the paucity of Ordovician exceptionally preserved open-m

189 al therapies is limited primarily because of the paucity of our understanding of their mechanism of a

190 ic leukemia (APL) remains unknown because of the paucity of outcome data available for patients treat

191 ing for this signature have been hampered by the paucity of palaeomagnetic intensity measurements, by

192 The paucity of PDL-derived osteoprogenitor cells in oste

193 All evidence reviews identified the paucity of pediatric data and the need for more rese

194 mobilization are not surprising in light of the paucity of pediatric-specific evidence.

195 itulated another pathological feature of VM, the paucity of pericytes around ectatic veins.

196 To date, the paucity of pertinent genetic materials has precluded

197 Further analysis suggested that the paucity of PMN accumulation was attributable to atte

198 he replication of both DNA strands, and that the paucity of pol3-L612M-generated errors on the leadin

199 However, owing to the paucity of polymeric immunoglobulin receptors and pl

200 tation to their use for on-field analysis is the paucity of preservation methods for long-term storag

201 However, the paucity of probes available for in vivo use has limi

202 The paucity of prophylactics and therapeutics against SU

203 routes and formulations of CSHT, as well as the paucity of prospective cohort studies, limits knowle

204 Our findings about the paucity of protective ILC3s immediately following tr

205 multiple, auxiliary iron-sulfur clusters and the paucity of protein X-ray structural data.

206 an syphilitic sera, a property attributed to the paucity of proteins in its outer membrane.

207 Given the paucity of proven data in treating COVID-19, managem

208 The paucity of public health messages that directly addr

209 Moreover, due to the paucity of published data about the issue, future mu

210 However, due to the paucity of published data about the topic, some conc

211 y between WNTs and FZDs has been hampered by the paucity of purified WNT proteins and by their appare

212 Given the paucity of quality randomized clinical trial data fo

213 Given the ubiquitous nature of failure and the paucity of quantitative approaches to understand it,

214 Part of the problem is the paucity of quantitative information on the ability o

215 ut their utility has been greatly limited by the paucity of quantitative temperature reconstructions.

216 Because of the paucity of randomized clinical trials (RCTs) in hemo

217 However, given the paucity of randomized controlled trials, lack of an

218 The paucity of randomized trials comparing curative mana

219 However, evidence is limited by the paucity of randomized trials.

220 The paucity of randomized, controlled trials in either o

221 The paucity of RCTs is a major limitation in the evaluat

222 iation are poorly understood and obscured by the paucity of recombination genes conserved in the M. g

223 The paucity of recombination near transcription start si

224 of targeted therapies for adult cancers, yet the paucity of recurrent somatic mutations or activated

225 mation of this has, however, been limited by the paucity of reliable methods for probing heteromeric

226 e recognized bottleneck to progress has been the paucity of reliable tools with which to explore astr

227 pattern of dominance of this mutation belies the paucity of reports of this disease in the literature

228 in melanoma brain metastasis are hampered by the paucity of reproducible and predictive animal models

229 We note the paucity of research into predictor variables other t

230 actor-kappaB ligand, possibly accounting for the paucity of resorptive cells and the dominance of min

231 Yet, the paucity of reverse genetic tools for choanoflagellat

232 t-generation sequencing method that exploits the paucity of ribonucleoside modifications at the 3'-en

233 However, the paucity of robust preclinical models of brain metast

234 The paucity of rPFH-VMH Ucn 3 projection is consistent w

235 Despite the paucity of scientific evidence supporting the safety

236 ecology and metabolism has been hampered by the paucity of sequenced reference genomes.

237 The paucity of shared gut colonizers suggests the existe

238 y the lack of explicit design principles and the paucity of simple high-throughput methods for select

239 we add strong support to the hypothesis that the paucity of SIV infections in wild populations is a g

240 Given the paucity of somatic driver mutations, we further perf

241 vivo has targeted exclusively mTORC1 due to the paucity of specific inhibitors to S6K1.

242 with either type of molecule alone; however, the paucity of specific reactions capable of functionali

243 The paucity of specific retinal findings associated with

244 ld aid in the study of native Env.IMPORTANCE The paucity of spikes on HIV is a unique feature that ha

245 formance testing is currently complicated by the paucity of standards and comparison metrics, as well

246 One reason for the paucity of structural and biochemical characterizati

247 Recognizing the paucity of structural and biophysical data on NBD2,

248 The paucity of structural information provides a fundame

249 The paucity of structural probes that are sensitive to n

250 derstood in any detail, not least because of the paucity of structural probes through which to study

251 education initiatives, this module addresses the paucity of structured training or education programs

252 Yet the paucity of studies aimed at understanding hybridizat

253 the two situations compare is unclear due to the paucity of studies on clinically silent infection.

254 This challenge is exacerbated by the paucity of suitable approaches to genetically engine

255 AML microenvironment in the bone marrow and the paucity of suitable immunotherapy targets limit the

256 ic conditions, however, is challenging given the paucity of suitable live-cell imaging tools.

257 major challenge in achieving these goals is the paucity of suitable preclinical animal models.

258 Given the scarcity of organs and the paucity of suitable recipients, prolonged ischemia t

259 The paucity of tactics for the synthesis of natural-prod

260 ivation remains poorly understood because of the paucity of technical means to produce site-specifica

261 closer to their upper thermal limits due to the paucity of temporary thermal refugia compared to tho

262 and when cultured in vitro, contrasting with the paucity of "Th1," "Th17," and T follicular helper ce

263 nt trials are needed, especially in light of the paucity of the current biologic treatment agents ava

264 ctive antidotes for lewisite was hampered by the paucity of the exact molecular mechanism underlying

265 nd tetanuran eggshells have been discovered; the paucity of the fossil record and the lack of interme

266 Despite the paucity of the literature, practical and concise sta

267 s on AMBN have been substantially limited by the paucity of the purified nondegraded protein.

268 However, the paucity of the S1 chymotrypsin/trypsin-like serine p

269 However, the paucity of the understanding of the G-quadruplex sta

270 vance of apraxia stands in stark contrast to the paucity of therapeutic options available.

271 s that constitute the metastatic cascade and the paucity of therapeutic options.

272 The paucity of therapies for tendon injuries is due to o

273 ire water- and DNA-compatible reactions, and the paucity of these reactions currently limit the chemi

274 To address the paucity of tissue for biological studies, we have es

275 or limitation in studying these responses is the paucity of tools available for detection, quantifica

276 a knowledge gap attributed in large part to the paucity of tools to genetically manipulate these pat

277 itivity for individual PAHs, and we describe the paucity of toxicological literature for many of thes

278 tively strict human tropism of the virus and the paucity of tractable experimental models.

279 The paucity of traditional epidemiological data during e

280 The paucity of transformations that involve the cleavage

281 ion of the underlying in vivo mechanisms due the paucity of transgenic models.

282 To address the paucity of treatment strategies, we developed an ele

283 - has been a promising strategy to overcome the paucity of treatments available for these debilitati

284 The paucity of treatments for malaria, coupled with the

285 d trafficking was not solely responsible for the paucity of Tregs in the lungs, as proliferation of b

286 In addition, given the paucity of trials focused on PDD treatment, studies

287 However, the paucity of tumor-associated enzymes which are essent

288 y rapidly decompose in solution underscoring the paucity of uranium phosphido complexes.

289 The paucity of V-ATPases in M1 phagosomes was associated

290 Despite the paucity of VDJ(H) rearrangements, microarray analysi

291 cement of their applications are hindered by the paucity of ways of reducing bandgaps and enhancing p

292 of known cellular phosphorylation sites, but the paucity of ways to identify kinases for particular p

293 The uncertainty associated with the paucity of well designed active-comparator trials ha

294 eriod (55-34 Myr ago) are unknown because of the paucity of well-dated records.

295 The paucity of well-defined studies currently renders a

296 Because of the paucity of well-defined synthetic examples, there ar

297 Noting the paucity of wet-bench data regarding combinatorial ef

298 The paucity of whole Y-chromosome sequences precluded co

299 ion of X-chromosomal genes, even considering the paucity of X-chromosomal gene expression during meio

300 reduction in mangroves can be attributed to the paucity of young elements; the rarity of young LTR-R