ライフサイエンスコーパス: theobromine

1 ol and kahweol), and alkaloids (caffeine and theobromine).

2 lucosyl-rhamnosyl-glucoside, theaflavin, and theobromine.

3 nvestigated with theophylline, caffeine, and theobromine.

4 to the determined values (RMSECV fat 1.08 %, theobromine 0.42 mg/g, caffeine 0.1 mg/g, sucrose 3.42 %

5 e models were as follows: R(2)(cv) fat 0.98, theobromine 0.94, caffeine 0.76, sucrose 0.92, cocoa 0.9

6 s of DNA-theophylline = 3.5x10(3) M(-1), DNA-theobromine = 1.1x10(3) M(-1), and DNA-Caffeine = 3.8x10

7 lline, paraxanthine, and 1-methylxanthine to theobromine, 3-methylxanthine, 7-methylxanthine, and xan

8 His(6)-NdmD catalyzed N(3)-demethylation of theobromine, 3-methylxanthine, caffeine, and theophyllin

9 l phenolics (338%), chlorogenic acid (483%), theobromine (323%), caffeine (251%), chlorophyll (321%),

10 tOH) produced a first fraction enriched with theobromine (75.05 +/- 9.22 %), a second fraction enrich

11 o Bonito in Chaco Canyon, New Mexico, reveal theobromine, a biomarker for cacao.

12 The present study demonstrates that theobromine, a methylxanthine derivative present in coco

13 duced action potentials upon presentation of theobromine, a methylxanthine in cocoa.

14 ed 1) cocoa, which naturally provided 150 mg theobromine and 325 mg flavonoids [cocoa intervention (C

15 nd added theobromine, which provided 1000 mg theobromine and 325 mg flavonoids [theobromine and cocoa

16 Given that theobromine and caffeine inhibit PDEs with equal potenci

17 he FTIR analysis divulged that theophylline, theobromine and caffeine interact with all the base pair

18 pure (-)-epicatechin and the methylxanthines theobromine and caffeine were consumed together.

19 urring methylxanthines such as theophylline, theobromine and caffeine with DNA, using UV absorption a

20 ver, cocoa also contains the methylxanthines theobromine and caffeine, which may also affect vascular

21 d 1000 mg theobromine and 325 mg flavonoids [theobromine and cocoa intervention (TB+CC)], or 4) neith

22 ether there is an interaction effect between theobromine and cocoa.

23 Theobromine and epicatechin are absorbed efficiently in

24 he significant difference in the contents of theobromine and flavanols prompted us to examine the coc

25 s the best to quantify the concentrations of theobromine and individual phenols in cocoa beans.

26 Caffeine metabolites like theobromine and paraxanthine had minimal interference du

27 plasma caffeine, paraxanthine, theophylline, theobromine and paraxanthine/caffeine ratio among up to

28 Despite the loss of some theobromine and phenols during fermentation, epicatechin

29 The enzyme was specific for caffeine and theobromine and showed no activity with xanthine.

30 s belonging to xanthine class (paraxanthine, theobromine and theophylline) were sensitive to alcohol

31 epicatechin, epicatechin gallate, caffeine, theobromine and theophylline.

32 etic route of purine alkaloids (caffeine and theobromine) and ureides in other plants are discussed.

33 Fat, sugar, theobromine, and caffeine are important compounds in cho

34 s (epicatechin and oligomeric procyanidins), theobromine, and magnesium.

35 of three caffeine metabolites, theophylline, theobromine, and paraxanthine, were also investigated.

36 l combinations of methylxanthines (caffeine, theobromine, and theophylline) indicative of stimulant d

37 detecting three molecular markers, caffeine, theobromine, and theophylline, associated with the use o

38 These data indicate the actions of theobromine appear to be peripherally mediated.

39 this effect is attributable to flavonoids or theobromine, both of which are major cocoa components.

40 ls (catechin, epicatechin), methylxanthines (theobromine, caffeine), total phenolic content, antioxid

41 surrounding smaller sites in Illinois reveal theobromine, caffeine, and ursolic acid, biomarkers for

42 inensis var. sinensis, with higher levels of theobromine, (+)-catechin, gallocatechin, gallocatechin

43 inensis var. sinensis, with higher levels of theobromine, (+)-catechin, gallocatechin, gallocatechin

44 easured maternal caffeine, paraxanthine, and theobromine concentrations from stored serum collected p

45 sues (cotyledons, shells) and extracts (pure theobromine, defatted cocoa solids, protein, lipids) obt

46 We also demonstrate that theobromine directly inhibits capsaicin-induced sensory

47 Catechin and theobromine exhibited higher effective bioaccessibility.

48 tive double helical DNA, and "theophylline>/=theobromine>caffeine to the denatured form of DNA and in

49 esterol, whereas insoluble-dietary-fibre and theobromine in DFCP were associated with the hypoglycemi

50 We investigated whether pure theobromine increases serum HDL cholesterol and whether

51 Theobromine independently increased serum HDL-cholestero

52 in yerba mate was 30 % higher, likely due to theobromine interference.

53 ervention (CC)], 2) 850 mg pure theobromine [theobromine intervention (TB)], 3) cocoa and added theob

54 of the caffeine synthase gene which converts theobromine into caffeine through an illegitimate recomb

55 We conclude theobromine is a novel and promising treatment, which ma

56 In contrast, CBB5 metabolized caffeine to theobromine (major metabolite) and paraxanthine (minor m

57 cocoa and interaction effects suggested that theobromine may be the main ingredient responsible for t

58 tabolites (i.e., caffeine, paraxanthine, and theobromine) measured from 1191 serum samples untimed to

59 f caffeine and its metabolites-theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxan

60 This strain used not only caffeine, theobromine, paraxanthine, and 7-methylxanthine as sole

61 3-Hydroxyvaleric acid, caffeine metabolites (theobromine, paraxanthine, and theophylline) and microbi

62 Theobromine-, paraxanthine-, and 7-methylxanthine-grown

63 tervention (TB+CC)], or 4) neither cocoa nor theobromine (placebo).

64 llate) and other alkaloids (theophylline and theobromine) present in tea samples were examined for se

65 The present study of theobromine residues confirms the continuous presence an

66 detectable serum caffeine, paraxanthine, and theobromine, respectively.

67 al change in the salicylic acid/benzoic acid/theobromine (SABATH) lineage of plant secondary metaboli

68 uble-blind, placebo-controlled study in man, theobromine suppresses capsaicin-induced cough with no a

69 with T1 FOR: 0.92; 95% CI: 0.75, 1.14), nor theobromine (T3 compared with T1 FOR: 1.15; 95% CI: 0.95

70 method for simultaneous analysis of MX i.e. Theobromine (TB), Theophylline (TH) and Caffeine (C), wi

71 < 0.05), coinciding with a rapid decline in theobromine (TB).

72 t), epicatechin (EpCat), caffeine (Caf), and theobromine (TeoB).

73 The dimethylxanthine alkaloid of theobromine (THB) is naturally found in various plants a

74 ds [cocoa intervention (CC)], 2) 850 mg pure theobromine [theobromine intervention (TB)], 3) cocoa an

75 for the three single demethylated analogues: theobromine, theophylline, and paraxanthine, highlightin

76 Quantified substances were theobromine, theophylline, caffeine, catechin, epicatech

77 binding affinity as "caffeine>/=theophylline>theobromine" to the native double helical DNA, and "theo

78 In contrast, theobromine (up to 80 mum) had no effect on TPA-induced

79 Conversely the percentage of theobromine used as a proxy measure for nonfat cocoa sol

80 nine (CpG) sites (FDR >5%), though pregnancy theobromine was associated with DNAm at cg09460369 near

81 erds has depended on the general presence of theobromine; we used the discrete presence of theophylli

82 ty was the most active and the catechins and theobromine were the chemical components of cocoa hinder

83 ty was the most active and the catechins and theobromine were the chemical components of cocoa hinder

84 ic acids) and two methylxanthines (caffeine, theobromine) were studied, according to the principles o

85 omine intervention (TB)], 3) cocoa and added theobromine, which provided 1000 mg theobromine and 325

86 he levels of epicatechin, procyanidin B2 and theobromine, while salsolinol significantly increased.

87 responsible for coffee characterization were theobromine, zeatin, phenylacetaldehyde, 2-acetyl-1-pyrr