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1 full cardiovascular activities for potential therapeutic application.
2 ich might not be desirable in light of human therapeutic application.
3 iac progenitor cells for widespread clinical therapeutic application.
4 on in wild-type COs, which thus limits their therapeutic application.
5 t and reproducible studies of EV biology and therapeutic application.
6 y of iPSCs is an important consideration for therapeutic application.
7 ey uptake, making it an excellent choice for therapeutic application.
8 typic alterations, with implications for its therapeutic application.
9  holds promise for a feasible osteoarthritis therapeutic application.
10 between homologous sequences, limiting their therapeutic application.
11  endomitosis with translatable potential for therapeutic application.
12 ered agent in preclinical development or for therapeutic application.
13 n K1 that could open up possibilities of its therapeutic application.
14 rome (CRS) and neurotoxicity, impeding their therapeutic application.
15 ential to revolutionise cell engineering for therapeutic applications.
16 cuss the perspectives of mTORC inhibitors in therapeutic applications.
17 re of increasing importance for wide ranging therapeutic applications.
18 nd can be exploited for chemical biology and therapeutic applications.
19 esign of efficient bispecific antibodies for therapeutic applications.
20 al cell responses with relevance to putative therapeutic applications.
21 for the development of future diagnostic and therapeutic applications.
22 ars, mainly due to its nutritional value and therapeutic applications.
23 oles of the six mATG8 homologs for potential therapeutic applications.
24 between their pathways is critical for their therapeutic applications.
25 stic biomarker of fatty liver with potential therapeutic applications.
26 form for protein-based material delivery for therapeutic applications.
27 target for the development of diagnostic and therapeutic applications.
28  certain biomedical research, diagnostic and therapeutic applications.
29 iew the opportunities for basic research and therapeutic applications.
30  immunosuppressive functions of IFNgamma for therapeutic applications.
31  and favorable tracer kinetics for potential therapeutic applications.
32 atable nanomaterials for both diagnostic and therapeutic applications.
33 strong, specific binding for engineering and therapeutic applications.
34  siRNA carriers for in vivo purposes towards therapeutic applications.
35 s to generate a scalable source of cells for therapeutic applications.
36 i-inflammatory proteins for potential future therapeutic applications.
37 ll biology and engineering of stem cells for therapeutic applications.
38 xtensively as pesticides and in a variety of therapeutic applications.
39 - or IRAK4-specific inhibitors for potential therapeutic applications.
40 ng tool and holds immense promise for future therapeutic applications.
41 mising strategy for fundamental research and therapeutic applications.
42  main challenges and prerequisites for their therapeutic applications.
43  cells (MSC) have been promoted for multiple therapeutic applications.
44 ct from infection and reduce viral load upon therapeutic applications.
45  in a broad range of biomedical research and therapeutic applications.
46 ase modeling, drug screening, and cell-based therapeutic applications.
47 y is an important property in industrial and therapeutic applications.
48 ractive biopolymer system for diagnostic and therapeutic applications.
49 h to generate multifunctional antibodies for therapeutic applications.
50 l interest to both life science research and therapeutic applications.
51 s9 system has triggered enormous interest in therapeutic applications.
52 coholic steatohepatitis, and their potential therapeutic applications.
53 idely studied and developed for cosmetic and therapeutic applications.
54 ogical/pathological processes, and potential therapeutic applications.
55  broadly applicable to numerous research and therapeutic applications.
56 n T cells could potentially be harnessed for therapeutic applications.
57 chemical scaffold for related imaging and/or therapeutic applications.
58 al for a variety of important diagnostic and therapeutic applications.
59 s potential antiviral targets with effective therapeutic applications.
60 ntial research applications and, especially, therapeutic applications.
61 ing hypoglycosylated alpha-DG, for potential therapeutic applications.
62 tem has potential use in many diagnostic and therapeutic applications.
63 r communication with possible diagnostic and therapeutic applications.
64 tion of highly specific fully human mAbs for therapeutic applications.
65 ing the groundwork for future diagnostic and therapeutic applications.
66 e broad utility in research, diagnostic, and therapeutic applications.
67 ons of PXR that can be explored for relevant therapeutic applications.
68 CE inhibitory potential for nutraceutical or therapeutic applications.
69 otential delivery vectors for diagnostic and therapeutic applications.
70 benefits of this approach for diagnostic and therapeutic applications.
71 he future to advance biomedical research and therapeutic applications.
72 cific brain circuits for neuroscientific and therapeutic applications.
73 ntiviral vectors (LVs) has several promising therapeutic applications.
74 rea of intense research due to its potential therapeutic applications.
75 d reduce off-target effects for research and therapeutic applications.
76 DNA binding affinity of deaminases for safer therapeutic applications.
77 ications on proteins for many biological and therapeutic applications.
78  new modes of biological activity, including therapeutic applications.
79 otherapy, stem cell reprogramming, and other therapeutic applications.
80 f protein-protein interactions for potential therapeutic applications.
81 signaling for basic science and possibly for therapeutic applications.
82 ing receptor-specific analogs with potential therapeutic applications.
83 cokinetic properties of oligonucleotides for therapeutic applications.
84  warrant further investigation for potential therapeutic applications.
85 g gene-corrected, patient-specific iPSCs for therapeutic applications.
86 obilized for imaging, biochemical assays, or therapeutic applications.
87 62 immunomodulatory mechanisms with possible therapeutic applications.
88 rnative to wild-type SpCas9 for research and therapeutic applications.
89 ces pave the way toward biotechnological and therapeutic applications.
90 ghting the potential use of this library for therapeutic applications.
91 evising new lecithin delivery strategies for therapeutic applications.
92 tion and the prospects of targeting Bub1 for therapeutic applications.
93 1 receptor, highlighting their potential for therapeutic applications.
94 prognostic biomarker and a target for future therapeutic applications.
95 eukemia cell models to explore its potential therapeutic applications.
96 and may facilitate the development of future therapeutic applications.
97 sicles and their potential in diagnostic and therapeutic applications.
98 ecule delivery to encapsulate stem cells for therapeutic applications.
99  2-fold increased efficacy, suggesting broad therapeutic applications.
100           In addition, miR-126 has potential therapeutic applications.
101 be of value for regenerative medicine and/or therapeutic applications.
102 imizing C-to-G base editors for research and therapeutic applications.
103 w a great potential for human diagnostic and therapeutic applications.
104 the use of gold quantum dots for imaging and therapeutic applications.
105 formations suggests advantages for potential therapeutic applications.
106 l biomarkers for diagnostic, prognostic, and therapeutic applications.
107 d specificity of DNA targeting for potential therapeutic applications.
108 potential of nanoparticles in diagnostic and therapeutic applications.
109 nd we discuss its stability and function for therapeutic applications.
110 tro and in vivo, and its inhibition may have therapeutic applications.
111 ting cytokine signaling as well as potential therapeutic applications.
112  development of S6K inhibitors with possible therapeutic applications.
113 ssay may have many potential mechanistic and therapeutic applications.
114 ompared with other agents, showing promising therapeutic applications.
115 te that GalNAc-conjugated PNAs have possible therapeutic applications.
116 n-display systems in vaccine development and therapeutic applications.
117 tant to both basic immunological studies and therapeutic applications.
118 r pathologies, with potential diagnostic and therapeutic applications.
119 emains a considerable concern, especially in therapeutic applications.
120 pulating ability, thereby limiting potential therapeutic applications.
121 des a steppingstone for potential downstream therapeutic applications.
122 ent knowledge gaps, potential solutions, and therapeutic applications.
123 ffects, as well as a wide-range of potential therapeutic applications.
124 d be used to culture human SSCs in vitro for therapeutic applications.
125 g knowledge have hindered the development of therapeutic applications.
126 logy holds great potential to develop future therapeutic applications.
127 JB2 a promising candidate for nanobody-based therapeutic applications.
128 antibodies for a broad range of research and therapeutic applications.
129 ficant challenge for vector effectiveness in therapeutic applications.
130 e guidelines for informed choice of GAGs for therapeutic applications.
131 t-mortem are frequently used for research or therapeutic applications.
132 urious off-target edits present a barrier to therapeutic applications.
133  materials for more effective diagnostic and therapeutic applications.
134 ionalities in cells for biotechnological and therapeutic applications.
135 logical materials has several diagnostic and therapeutic applications.
136 ite-selective modification of antibodies for therapeutic applications.
137 ool to design novel molecules with potential therapeutic applications.
138 tems compatible with both research and human therapeutic applications.
139 increasingly used for research and potential therapeutic applications(1,2).
140 pulation of eukaryotic genomes for potential therapeutic applications(1-4).
141  highlight the potential of MAb 53C10 in the therapeutic application against H1 influenza virus infec
142 drial metabolic vulnerability with potential therapeutic applications against chemotherapy-resistant
143  FA patients, gene editing holds promise for therapeutic applications aimed at functionally restoring
144                    This review addresses the therapeutic application and molecular mechanisms that un
145 al from Cannabis sativa with a wide range of therapeutic applications and a long history of recreatio
146 e emerged as leading gene delivery tools for therapeutic applications and biomedical research.
147          This creates a potential hazard for therapeutic applications and could confound results in b
148 tic resistance and considerations for future therapeutic applications and translation into the clinic
149 l deficits, the rapid expansion of potential therapeutic applications and ultrasound pulse-train prot
150  investigations concerning cancer diagnosis, therapeutic applications, and drug efficacy tests.
151 new strategies to engineer TIMP proteins for therapeutic applications, and our directed evolution app
152                        Sweet orange exhibits therapeutic applications as being effective anti-diabeti
153 uthful cells is currently being explored for therapeutic applications, aspects that relate to acceler
154 e hard to manipulate, focusing translational therapeutic applications at the environments appears to
155  antitoxin agents are not only promising for therapeutic applications, but also can be used as tools
156  molecules valued not only for their diverse therapeutic applications, but also for their role in con
157 rative potential is important to develop new therapeutic applications, but the identification advance
158          Reprogramming approaches could find therapeutic applications by inducing beta cell conversio
159 er, transgene expression is not amenable for therapeutic application due to potential insertional mut
160 ious limitations for advanced prosthetic and therapeutic applications due primarily to their lack of
161 or beta (TGFbeta) superfamily with potential therapeutic applications due to their broad biological f
162 al/clinical development for prophylactic and therapeutic applications due to their potency and their
163 ioxidant and anti-inflammatory agent used in therapeutic applications, e.g. in the treatment of diabe
164 for development of RNA origami for potential therapeutic applications especially as a safer surgical
165 the dystrophin glycoprotein complex may have therapeutic application for all DMD patients, regardless
166      Taken together, our work suggests a new therapeutic application for Ambrisentan in the treatment
167              These findings indicate a novel therapeutic application for mTOR inhibitors to disrupt e
168 sing on practical aspects of their potential therapeutic application for selective inhibition of smoo
169  biological processes and in their potential therapeutic application for stress-related psychopatholo
170 hus, videogame training might have important therapeutic applications for amblyopia and other visual
171 ive cancer phenotypes and offer insight into therapeutic applications for better survival of patients
172  the development of diagnostic, imaging, and therapeutic applications for cancers that express the an
173 ntal for regenerative medicine as well as in therapeutic applications for immune-related diseases.
174      As such, these molecules have potential therapeutic applications for myriad indications, with se
175 ro, and recent studies have demonstrated new therapeutic applications for passively administered bNAb
176 es in HNSCC progression, including potential therapeutic applications for such enzymes in combination
177            There are numerous diagnostic and therapeutic applications for the detection and enumerati
178 ase gene signatures to display the potential therapeutic applications for these approaches.
179 n and proliferation, and highlight potential therapeutic applications for this SPM to promote mucosal
180 be used for the identification of genes with therapeutic applications for treating infectious, inflam
181 h for enhancing IGF1 signaling has potential therapeutic applications for treating skeletal muscle at
182 ion should be further explored for potential therapeutic applications.FUNDINGNetherlands Organization
183 e reagents remains a concern, especially for therapeutic applications, given the potential mutagenic
184 ing a sufficient quantity of CO for possible therapeutic applications has been studied using a cell c
185  and agents amenable to tissue targeting for therapeutic application have been lacking.
186 evelopments towards an improved compound for therapeutic application have identified FAPI-46 as a pro
187 developments toward an improved compound for therapeutic application have identified FAPI-46 as a pro
188                             For a successful therapeutic application, however, FimH antagonists shoul
189 ibuted extensively to basic neuroscience and therapeutic applications; however, the dimensional and m
190 mutations, opening the opportunity for their therapeutic application in an autologous transplantation
191 chanism of action of OSU-T315 with potential therapeutic application in CLL.
192 terial collagenase inhibitors with potential therapeutic application in humans.
193 richuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (
194 for the development of a drug candidate with therapeutic application in mitochondrial oxidative stres
195 rough distinct pathways, providing potential therapeutic application in ocular vascular disease.
196 s been widely documented and their potential therapeutic application in regenerative medicine or angi
197 t peptide motifs and provide a blueprint for therapeutic applications in a variety of cancers and per
198  actively pursued because of their potential therapeutic applications in cancer and other diseases.
199  to investigate haematopoietic processes for therapeutic applications in cancer, infection and cardio
200  bufalin and lycorine as drug candidates for therapeutic applications in cardiac fibrosis and diastol
201 rch, drug discovery, precision medicine, and therapeutic applications in cardiac regeneration.
202  and PEA have endogenous roles and potential therapeutic applications in conditions of intestinal hyp
203 th receptor activation should have important therapeutic applications in diseases such as nonalcoholi
204  The finding has mechanistic and potentially therapeutic applications in hepatocyte growth biology, h
205 ed short palindromic repeats) technology for therapeutic applications in humans, focusing on specific
206 ibitors of BET proteins could have important therapeutic applications in inflammatory renal diseases.
207 n this RDEB model strongly supports proposed therapeutic applications in man.
208 h respect to proof-of-concept cardiovascular therapeutic applications in mouse models-which might eve
209 rs can be further studied to determine their therapeutic applications in neurologic disorders.
210 benign adipose tissue expansion and may have therapeutic applications in obesity or lipodystrophy.
211 diovascular basic science research, possible therapeutic applications in patients with cardiovascular
212  represent a safer alternative for potential therapeutic applications in patients with ischemic myoca
213 integration and provide motivation for novel therapeutic applications in patients with lexical-semant
214 nstructs have become widely used formats for therapeutic applications in recent years.
215                      The use of exosomes for therapeutic applications in stroke is also highlighted.
216                Biomaterials hold promise for therapeutic applications in the central nervous system (
217                                           In therapeutic applications in the clinical setting, gene t
218 les and opens the door to novel research and therapeutic applications in the field of custom RNA pack
219 f the CRISPR-Cas system, and outline current therapeutic applications in their clinical translation.
220                        siRNAs have potential therapeutic applications in various dermatological disea
221                                           In therapeutic applications in which the Fc of IgG is criti
222 , skin rejuvenation and hair growth, and for therapeutic applications including influenza vaccination
223 sent a relatively new target system for many therapeutic applications including pain regulation, modu
224  or stromal cells (MSCs) have many potential therapeutic applications including therapies for cancers
225                                 However, for therapeutic applications, intracellular delivery of pept
226  expression has been shown to have potential therapeutic applications, making the enzyme a promising
227                                              Therapeutic application of (131)I in RANTES-NIS-MSC-trea
228 of venous thrombi in vivo, and the potential therapeutic application of a p53 agonist as a treatment
229                                              Therapeutic application of a specific CB2 antagonist als
230 ells in the CNS, which will foster effective therapeutic application of allogeneic stem cells.
231 scuss both current challenges preventing the therapeutic application of alternative TSAs and potentia
232                             Prophylactic and therapeutic application of CV07-209 protected hamsters f
233 e data represent a proof-of-principle that a therapeutic application of DIPs to combat NiV infections
234     These findings have implications for the therapeutic application of FGFR inhibitors as they ident
235                     Because of the potential therapeutic application of GAG polymers, fragments, and
236 owever, one of the major limitations for the therapeutic application of human MSC (hMSC) is the lengt
237                                          The therapeutic application of iPSC-derived MSCs may now be
238                    In addition, the possible therapeutic application of NIR probes to block the patho
239                                          The therapeutic application of nitric oxide, an endogenous c
240                                              Therapeutic application of novel vaccines adjunct to ant
241           This study emphasizes the possible therapeutic application of NRF2 inducers in autoimmune d
242 l and clinical studies aiming to broaden the therapeutic application of PARPis identified sensitivity
243  present study suggest the potential for the therapeutic application of PKCalphabeta inhibition in AC
244  an explosion of new work with regard to the therapeutic application of proresolving ligands in exper
245 ated infections and provide guidance for the therapeutic application of QS blockers.
246 has important implications for the potential therapeutic application of quorum-sensing blockers.
247 ation of pancreatic tissue and prohibits the therapeutic application of radiolabeled exendin for beta
248                            The potential for therapeutic application of splice-switching oligonucleot
249 sensory functions that could be rescued with therapeutic application of the heat shock protein in viv
250                To evaluate the potential for therapeutic application of the hu.32 serotype in a gyren
251 tors or inhibitors and discuss the potential therapeutic application of their ligands.
252               We also evaluate the potential therapeutic application of these compounds in different
253  between patients, which will be crucial for therapeutic application of this technology.
254 psychiatric and neurodegenerative disorders, therapeutic application of VEGFD may help to stabilize d
255 hibitor (FAPI) (68)Ga-FAPI-04, and the first therapeutic applications of (90)Y-FAPI-04 have been appl
256             These results showcase potential therapeutic applications of 17e in both vaccine adjuvant
257                   However, realizing broader therapeutic applications of CAR-T cells necessitates eng
258  desirable in basic stem cell technology and therapeutic applications of cells.
259                                     However, therapeutic applications of Delta(9)-tetrahydrocannabino
260 orted populations, underlining the potential therapeutic applications of GP2.Pancreatic progenitors (
261 is Review addresses the emerging biology and therapeutic applications of human ARSs in diseases inclu
262                          We also discuss the therapeutic applications of native and bioengineered EVs
263 ew could have important implications for the therapeutic applications of oxytocin in conditions chara
264                                              Therapeutic applications of peptides are currently limit
265                         It is of concern for therapeutic applications of PSMA radioligands, because t
266 ellum of the AS mouse model and on potential therapeutic applications of rapamycin.
267 ons in the design of biomaterials to enhance therapeutic applications of stem cells.
268                  It also discusses potential therapeutic applications of targeting the GDF15-GFRAL pa
269 ever, the study of iNKT cell biology and the therapeutic applications of these cells are greatly limi
270 by OT release and underscore the potentially therapeutic applications of these methods for disorders
271                                        Human therapeutic applications of these technologies will ulti
272 the context of GVHD, and discusses potential therapeutic applications of Tregs in the prevention or t
273 y provides the proof of principle to support therapeutic applications of viral-vectored vaccines via
274                           Genome editing for therapeutic applications often requires cleavage within
275 xploited as carriers for in vivo imaging and therapeutic applications, owing to their capability to e
276 roy target proteins for biotechnological and therapeutic applications.Proteases are promising therape
277                           Consequently, each therapeutic application requires different settings: non
278 er doses, thereby improving the outcome of a therapeutic application, several FAPI variants were desi
279 high temperatures and acidic environments of therapeutic applications significantly limiting therapeu
280 unately, kidney toxicity has precluded their therapeutic application so far.
281 n vivo screening and design of LNPs for mRNA therapeutic applications such as CRISPR-Cas9 gene editin
282 ic nanoparticles are promising new tools for therapeutic applications, such as magnetic nanoparticle
283 vo cardiac function of IF1 and the potential therapeutic application targeting IF1 remain obscure.
284          In this context, we discuss current therapeutic applications targeting these cytokine pathwa
285 delivery, and explore the array of potential therapeutic applications that have been reported.
286 9) limits its utility for basic research and therapeutic applications that use the highly versatile a
287 ly broad translatability of our strategy for therapeutic applications.The therapeutic use of single-c
288 ilitate exciting new avenues of research and therapeutic applications through AAV-based delivery of C
289 tive disorders, but also seem to have unique therapeutic applications to directly target and remodel
290 ers considerable promise for a wide range of therapeutic applications, toward a greatly enhanced outc
291 opriate hydrolytic stability to expand their therapeutic applications towards more advanced areas.
292  of new molecular targets for diagnostic and therapeutic applications using in vitro methods is an im
293 s, representing a new alternative for future therapeutic applications via this route.
294 o determine the potential use of Lawsone for therapeutic application, we harnessed human, murine and
295 oire elicited by WNV infection for potential therapeutic application, we isolated ten mAbs from WNV-i
296 , which have gained increasing attention for therapeutic applications, were shown to stimulate T lymp
297  in prostate cancer raise concerns about its therapeutic application, which need to be evaluated in f
298 s in the implementation of nanoparticles for therapeutic applications will accelerate with an improve
299 m will enable new industrial, diagnostic and therapeutic applications with engineered cells.
300 izure-induced astrocyte injury and potential therapeutic applications with mTOR inhibitors.

 
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