ライフサイエンスコーパス: thermotolerance

1 o protect cells from severe stress (acquired thermotolerance).

2 6 and find that FBXA-158 and FBXA-75 promote thermotolerance.

3 is an equatorial perennial with a high basal thermotolerance.

4 n vivo and in vitro, as well as for cellular thermotolerance.

5 ere heat shock, a phenomenon called splicing thermotolerance.

6 sh1 recA3 double mutants exhibiting enhanced thermotolerance.

7 s to resolve fine-scale differences in coral thermotolerance.

8 romie et al., also confers similar increased thermotolerance.

9 teins and are molecular machines involved in thermotolerance.

10 for panA knockouts, which displayed enhanced thermotolerance.

11 NO-overproducing mutant is also defective in thermotolerance.

12 Htg6.1) from UC96US23 conferring germination thermotolerance.

13 late these genes nor does it further enhance thermotolerance.

14 ts as a core component with CUL-6 to promote thermotolerance.

15 e thermally activated, resulting in enhanced thermotolerance.

16 variations in basal transcription influence thermotolerance.

17 vated temperatures and defective in acquired thermotolerance.

18 Flies with Hsp70 deletions have reduced thermotolerance.

19 ability during heat shock and lower acquired thermotolerance.

20 hereas HLP1 overexpressors display increased thermotolerance.

21 otolerance, it is not essential for acquired thermotolerance.

22 but had a greatly reduced ability to promote thermotolerance.

23 w that Glc has a prominent role in providing thermotolerance.

24 a role in mediating the effects of acquired thermotolerance.

25 P70) synthesis and blocks the development of thermotolerance.

26 a chaperone function of an sHSP in cellular thermotolerance.

27 age compensation but regulates longevity and thermotolerance.

28 ved thermotolerance, whereas alkanes reduced thermotolerance.

29 vasation, indicating development of vascular thermotolerance.

30 iating a role for TOR-E2Fa-HLP1 in providing thermotolerance.

31 ce, and hot1 seeds had greatly reduced basal thermotolerance.

32 ion of these kinases did not reduce acquired thermotolerance.

33 y for JNK downregulation and is critical for thermotolerance.

34 t the hypothesis that isoprene enhances leaf thermotolerance.

35 stress (HS) is indispensable for conferring thermotolerance.

36 at DnaJ plays an important role in C. jejuni thermotolerance.

37 an RpoS-dependent role in starvation-induced thermotolerance.

38 r ER molecular chaperones and thereby induce thermotolerance.

39 the proteasome inhibitors might also confer thermotolerance.

40 me facultative symbionts directly alter host thermotolerance.

41 perature whereas a ypuN mutant has increased thermotolerance.

42 roxide dismutase genes caused an increase in thermotolerance.

43 els of Hsp1O4 are sufficient to provide full thermotolerance.

44 ting Hsp1O4 plays a critical role in induced thermotolerance.

45 ons caused a 500- to 20,000-fold increase in thermotolerance.

46 tress response which allows cells to acquire thermotolerance.

47 f mtl-1 and hsp-70 promotes biofilm-mediated thermotolerance.

48 the induction of Hsps does not block induced thermotolerance.

49 49220) that both consistently showed reduced thermotolerance.

50 s essential to establish short-term acquired thermotolerance.

51 dity and silencing Hsp70 reduced JGM-induced thermotolerance.

52 a pivotal role in the response to ABA and in thermotolerance.

53 ortant role for HsfA2 in regulating acquired thermotolerance.

54 velop lettuce lines that exhibit germination thermotolerance.

55 uption is an important component of vascular thermotolerance.

56 ssolves heat-induced aggregates and promotes thermotolerance.

57 ents that act together with CUL-6 to promote thermotolerance.

58 consistent with the development of vascular thermotolerance.

59 acclimation to evolve separately from basal thermotolerance.

60 , particularly in assays of diet breadth and thermotolerance.

61 or NAC019 in Arabidopsis thaliana increases thermotolerance.

62 xhibit severely impaired HSR and compromised thermotolerance.

63 terial cells instead of improvement of their thermotolerance.

64 HSF-FoxM1 connection that mediates cellular thermotolerance.

65 n regulating thermotolerance and in acquired thermotolerance.

66 tol-sensitive mechanisms that enhance Q-cell thermotolerance.

67 inolytic peptidase B chaperonin required for thermotolerance.

68 heat-challenged adults, suggesting a role in thermotolerance.

69 , such as pathogen defense, development, and thermotolerance.

70 HSR, leading to the onset of plant acquired thermotolerance.

71 r the A. thaliana FtsH11-encoded protease in thermotolerance, a function previously reported for bact

72 brogating TAD structure did, however, reduce thermotolerance, accelerate aging, and shorten lifespan,

73 on tests showed that HSFA6b was required for thermotolerance acquisition.

74 ensitive mutants (atts) that fail to acquire thermotolerance after pre-conditioning at 38 degrees C.

75 s in many organisms correlates with enhanced thermotolerance, altered growth, and development.

76 ntenance of symbiosis and (b) acquisition of thermotolerance among coral reef organisms.

77 Both basal thermotolerance and acclimation are thought to be import

78 lenging for ectotherms, which use both basal thermotolerance and acclimation, an adaptive plastic res

79 lelic variants of SSD1 regulate the level of thermotolerance and cell wall remodeling.

80 mRNA and protein, which was associated with thermotolerance and cytoprotection from TNFalpha+actinom

81 We tested thermotolerance and expression of pathogenesis-related (

82 MBF1c is required for thermotolerance and functions upstream to SA, trehalose,

83 However, the levels of thermotolerance and hyper-osmotolerance were not associa

84 hromatin regulation play roles in regulating thermotolerance and in acquired thermotolerance.

85 esulted in deficient maintenance of acquired thermotolerance and increased sensitivity to heat stress

86 with the purity required to study plant cell thermotolerance and its relationship to plant cell survi

87 that the mechanisms by which H(2)S increases thermotolerance and lifespan in nematodes are conserved

88 bunit IV in LACK-deficient L. major restored thermotolerance and macrophage infectivity.

89 on of JNK is therefore critical for acquired thermotolerance and may play a role in tolerance to othe

90 a novel stress response protein required for thermotolerance and mitigation of oxidative stress-induc

91 Osmotic stress is known to increase the thermotolerance and oxidative-stress resistance of bacte

92 s from nutrient excess, and is essential for thermotolerance and parasite infectivity in the mammalia

93 signalling is required for differentiation, thermotolerance and pathogenesis in C. neoformans.

94 These variants were tested for both improved thermotolerance and performance in the bioscouring appli

95 or thermotolerance, uncovers a role of NO in thermotolerance and plant development.

96 nstrate that BOB1 is required for organismal thermotolerance and postembryonic development.

97 To determine P. sulfincola thermotolerance and preference, we developed a high-pres

98 upported [PSI(+)] and functioned normally in thermotolerance and protein disaggregation.

99 nterestingly, pals-22 mutants have increased thermotolerance and reduced levels of stress-induced pol

100 tes dramatically during heat shock, enhances thermotolerance and reduces aggregation of denatured pro

101 stationary phase in many organisms, enhances thermotolerance and reduces aggregation of denatured pro

102 Depletion of nsun-1 or nsun-5 improved thermotolerance and slightly increased locomotion at mid

103 cylic acid pathways are involved in acquired thermotolerance and that UVH6 plays a significant role i

104 ellular processes, namely the acquisition of thermotolerance and the refolding of thermally denatured

105 l signaling mechanisms that lead to acquired thermotolerance and thermoinhibition.

106 ation of protein aggregates is essential for thermotolerance and to facilitate the maintenance of pri

107 nase (RACK1), that is important for parasite thermotolerance and virulence.

108 oreover, we demonstrate that Ydj1p-dependent thermotolerance and Ydj1p localization are perturbed whe

109 phenotype in two assays of Hsp104 function (thermotolerance and yeast prion propagation), demonstrat

110 C), which is critical for the acquisition of thermotolerance, and At1g74320 encodes for choline kinas

111 Research on biology, host range and shifts, thermotolerance, and demography has provided useful info

112 d hot1 seedlings were also unable to acquire thermotolerance, and hot1 seeds had greatly reduced basa

113 ed to increased ESRE transcription, enhanced thermotolerance, and induction of a nuclear ESRE-binding

114 f pat-10 increased actin filament stability, thermotolerance, and longevity, indicating that in addit

115 1 contribute to optimum growth, development, thermotolerance, and regulation of the heat shock respon

116 These features of high yield, extreme thermotolerance, and satisfactory immunogenicity suggest

117 l CP-sHSP isoforms was genetically linked to thermotolerance, and that the presence of the additional

118 anisms underlying this mitochondria-specific thermotolerance are still largely unclear.

119 f a cullin-RING ligase complex that promotes thermotolerance as part of the IPR in C. elegans, which

120 abscisic acid (ABA) is involved in acquired thermotolerance as well.

121 In thermotolerance assays hot1-3 shows a similar, though so

122 Thermotolerance assays of PME gene T-DNA insertion lines

123 Measurement of thermotolerance at different growth stages reveals that

124 enic line were tested for basal and acquired thermotolerance at different stages of growth.

125 henotype, giving rise to an HSR and acquired thermotolerance at significantly milder heat-priming tre

126 0-day-old seedlings, and it is wild type for thermotolerance at these stages.

127 Acquired thermotolerance (AT) is the ability of cells to survive

128 dine lactam inhibitor of hsp70 induction and thermotolerance, attenuated 17-AAG-mediated hsp70 induct

129 r heat stress-responsive gene regulation and thermotolerance, because, compared with the wild type, t

130 ogether had synergistic effects in promoting thermotolerance but did not increase hsp expression beyo

131 een significantly increased exhibit improved thermotolerance but display no detectable difference in

132 eat-shock protein (Hsp) is involved in plant thermotolerance but its site of action is unknown.

133 en a genetic approach to dissecting acquired thermotolerance by characterizing loss-of-function therm

134 tudy not only suggests that AtPARK13 confers thermotolerance by degrading misfolded protein targets,

135 It has been suggested that isoprene improves thermotolerance by helping photosynthesis cope with high

136 Hsp100/ClpB chaperone (AtHsp101) in acquired thermotolerance by isolating recessive, loss-of-function

137 an Arabidopsis line engineered for increased thermotolerance by overexpressing the cytosolic isoform

138 increased Mg(2+) accumulation might enhance thermotolerance by protecting the integrity of proteins

139 to Hsf1 activation and subsequently induced thermotolerance by thiol-reactive compounds, but not by

140 Potential thermotolerance candidate loci contained within our QTL

141 ts conferring tolerance to these stressors - thermotolerance, cold hardiness, and water deficit stres

142 All four cngc mutants showed thermotolerance compared to wild-type, although CNGC12 d

143 genes critical for cognition, olfaction, and thermotolerance, consistent with the observed patterns o

144 the reversible inhibitor MG132 was removed, thermotolerance decreased rapidly, while synthesis of hs

145 In addition to exhibiting a thermotolerance defect as assayed by hypocotyl elongatio

146 s and its expression in yeast complemented a thermotolerance defect caused by a deletion of the HSP10

147 Mutants were assessed for thermotolerance defects in seed germination, hypocotyl e

148 In addition to thermotolerance defects, bob1-3 exhibits pleiotropic dev

149 was performed to define the nature of their thermotolerance defects.

150 ly resistant to guanidine, and the degree of thermotolerance did not correlate with [PSI(+)] stabilit

151 Although thermotolerance did not correlate with hsp content, anot

152 ce, consistent with the observed patterns of thermotolerance differences and assortative mating.

153 ability of both approaches to resolve coral thermotolerance differences reflective of in situ reef t

154 ently involved an NPR1-dependent pathway but thermotolerance during HS did not.

155 for the priming process that sustains pollen thermotolerance during microsporogenesis.

156 SA promoted thermotolerance during the HS itself and subsequent reco

157 previously unrecognized strategy to achieve thermotolerance, especially for the protection of reprod

158 ) were more defective in basal than acquired thermotolerance, especially under high light.

159 on/repair pathway for denatured proteins and thermotolerance expression in vivo.

160 Hsp70 is a broadly conserved thermotolerance factor, but inhibits growth at normal te

161 NBD) of Hsp104 (NBD1 and NBD2) eliminate its thermotolerance function in vivo.

162 t is not toxic but specifically inhibits the thermotolerance function of WT Hsp104.

163 ells subject to nutrient limitation, but its thermotolerance function remained unaffected.

164 8 degrees C sensitivity, but did not restore thermotolerance function to hot1-4, and Class 2 suppress

165 d Class 2 suppressors that restored acquired thermotolerance function to hot1-4.

166 hock protein that has both developmental and thermotolerance functions and may play a role in both of

167 contribution to this phenotype or that other thermotolerance genes encode essential or redundant func

168 However, the evidence for the thermotolerance hypothesis is indirect and one of three

169 ed in processes predicted to be required for thermotolerance (i.e. protection of proteins and of tran

170 evidence for SA-dependent signaling in basal thermotolerance (i.e. tolerance of HS without prior heat

171 in bacteria and yeast, is also essential for thermotolerance in a complex eukaryote.

172 show that elevated levels of AtPARK13 confer thermotolerance in A. thaliana.

173 lipid metabolism and TAG formation increases thermotolerance in addition to the genetically encoded H

174 nhibition of DDL-1/2 increases longevity and thermotolerance in an hsf-1-dependent manner.

175 n bridging factor 1c), is a key regulator of thermotolerance in Arabidopsis thaliana.

176 at BABA also significantly enhances acquired thermotolerance in Arabidopsis.

177 r heat stress-responsive gene expression and thermotolerance in Arabidopsis.

178 ic analysis showed that the loss of acquired thermotolerance in AtTS02 was a recessive trait.

179 evidence that Hsp101, which is required for thermotolerance in bacteria and yeast, is also essential

180 t exposure to H2S increases the lifespan and thermotolerance in Caenorhabditis elegans, and improves

181 e and secondary metabolites ingrained higher thermotolerance in cv. Unnat Halna, among others.

182 okaryotic homolog of Hsp90, is essential for thermotolerance in cyanobacteria, and in vitro it suppre

183 was compared with cultivated rice, revealing thermotolerance in growth and photosynthetic processes a

184 ppears to be a major contributor to acquired thermotolerance in mammalian cells.

185 vides an excellent prospect for manipulating thermotolerance in other species.

186 igase component cullin cul-6, which promotes thermotolerance in pals-22 mutants.

187 associated with the concomitant induction of thermotolerance in PDT-treated cells.

188 nscription factors play an important role in thermotolerance in plants and other organisms, controlli

189 rone that is required for the development of thermotolerance in plants and other organisms.

190 protein101 (HSP101) is required for acquired thermotolerance in plants and other organisms.

191 ast ortholog, Hsp104, are required to confer thermotolerance in plants and yeast (Saccharomyces cerev

192 ere recently shown to play a central role in thermotolerance in plants, a key regulator of these resp

193 To identify the various mechanisms of thermotolerance in plants, we isolated a series of Arabi

194 -generated stress signal that enhances basal thermotolerance in plants.

195 cs associated with the induction of acquired thermotolerance in response to heat shock and acquired f

196 In a genetic analysis of the determinants of thermotolerance in S. enterica serovar Typhimurium, we i

197 CA) cycle metabolite, increased lifespan and thermotolerance in the nematode C. elegans.

198 ost and its expression resulted in increased thermotolerance in tobacco.

199 lar functions, including endowing cells with thermotolerance in vivo and being able to act as molecul

200 educed the ability of the protein to provide thermotolerance in vivo.

201 Hsp104 disaggregase provides thermotolerance in yeast by recovering proteins from agg

202 ind ClpB supports both prion propagation and thermotolerance in yeast if it is modified to interact w

203 Our findings show prion propagation and thermotolerance in yeast minimally require cooperation o

204 ibutions in acquired cellular resistance or "thermotolerance" in mammalian cells is presently unknown

205 dependent of Hsp synthesis, are required for thermotolerance, including protection of membrane integr

206 l risk assessment revealed that the enhanced thermotolerance increases the length of time in which th

207 xidative damage is the likely cause of shot1 thermotolerance, indicating HSP101 repairs protein oxida

208 Glc-mediated thermotolerance involves HSP induction via the TARGET OF

209 Acquired thermotolerance is a complex physiological phenomenon th

210 Our data thus provide evidence that splicing thermotolerance is acquired through maintenance of SRSF1

211 Acquired thermotolerance is actively maintained over several days

212 itive to heat stress and because the reduced thermotolerance is correlated with lower expression of m

213 A(+)) mRNA accumulation upon heat shock, and thermotolerance is decreased in a nup42 nab2-T178A/S180A

214 Acquisition of thermotolerance is likely to be of particular importance

215 nteraction analysis that the role of Tps1 in thermotolerance is not dependent upon Hsf1-dependent tra

216 d by HSPs, but the mechanistic basis of this thermotolerance is not well defined.

217 Although SA promotes basal thermotolerance, it is not essential for acquired thermo

218 ult longevity (Age), and increased intrinsic thermotolerance (Itt).

219 mperature incubation step, and the resulting thermotolerance landscape allowed the discovery of mutat

220 We argue that acquisition of thermotolerance may represent a positive selection for t

221 d for the extension of lifespan and enhanced thermotolerance mediated by extra copies of the deacetyl

222 atases involved in various processes such as thermotolerance, melanin and capsule production, stress

223 tolerance by characterizing loss-of-function thermotolerance mutants in Arabidopsis.

224 cribes a procedure for selection of acquired thermotolerance mutants, and provides the physiological

225 The thermotolerance of anaerobically grown cells is not due

226 Thermotolerance of cells expressing mutant proteins was

227 The thermotolerance of cells in anaerobic conditions was imm

228 established role for ethylene in germination thermotolerance of Compositae seeds.

229 tenfold reduced level, resulting in reduced thermotolerance of germinating seeds and underscoring th

230 re a substantial and durable increase in the thermotolerance of hybrid poplar (Populus tremulaxPopulu

231 recessive alleles of four loci required for thermotolerance of hypocotyl elongation, hot1-1, hot2-1,

232 creased level of thiolated tRNA and enhanced thermotolerance of indica rice varieties.

233 Thermotolerance of luciferase activity and of ion leakag

234 It is concluded that thermotolerance of photosynthesis is a substantial benef

235 is an important mechanism for improving the thermotolerance of plant photosystems as temperatures in

236 ce that leaf-internal isoprene increases the thermotolerance of plants and protects them against oxid

237 h6, showed the strongest defects in acquired thermotolerance of root growth and seedling survival.

238 otein of Bacillus subtilis also enhanced the thermotolerance of S. enterica.

239 hanism by which high osmolality enhances the thermotolerance of Salmonella enterica serovar Typhimuri

240 y high temperature and did not contribute to thermotolerance of seedlings.

241 Because thermotolerance of Synechocystis depends on HSP16.6, a p

242 ver of adaptation, resulting in an increased thermotolerance of the 30 degrees C adapted populations,

243 However, the thermotolerance of the two species differs: while A. fum

244 Furthermore, this "thermotolerance" of SRSF10 phosphorylation, like that of

245 ression of SEC-1 in Escherichia coli confers thermotolerance on the bacterium.

246 arental lines, we mapped seven QTL affecting thermotolerance on the second and third chromosomes.

247 but insufficient is known about its role in thermotolerance or how this relates to SA signaling in p

248 lpha-decarboxylase had significantly greater thermotolerance (P<or=0.05) during germination.

249 otein level was correlated with the acquired thermotolerance phenotype.

250 in complex patterns of genetic variation in thermotolerance phenotypes in nature.

251 (Oregon-R and 2b) that were not selected for thermotolerance phenotypes, but exhibit significant gene

252 nderstand and identify the genes controlling thermotolerance phenotypes, we have used a mapping popul

253 These findings indicate that increased thermotolerance post-bleaching resulted from symbiont co

254 induction temperatures for maximum acquired thermotolerance prior to a high temperature challenge we

255 accumulation levels (our measure of acquired thermotolerance) ranging from 10% to 98% of control seed

256 JGM treatments led to increased thermotolerance, recorded as decreased mortality under h

257 ere directed primarily by Hsp40 Sis1p, while thermotolerance relied mainly on Hsp40 Ydj1p.

258 ock, indicating that a significant degree of thermotolerance remains in the absence of Hsp70.

259 ing cpr5 genotypes having lowest and highest thermotolerance, respectively.

260 s, such as mitochondrial protein maturation, thermotolerance, senescence, or enriched subcellular loc

261 L66A causes severe defects in thermotolerance, suggesting that oligomeric stability of

262 , mutants lacking components of the acquired thermotolerance system were isolated.

263 t mutants are the first mutants defective in thermotolerance that have been isolated in a higher euka

264 cumulate heat shock protein 70 and develop a thermotolerance that, upon transfer of cells to 32 degre

265 function of Glc-regulated HLP1 in mediating thermotolerance/thermomemory response.

266 and were reduced in plants that had acquired thermotolerance through a mild heat pretreatment.

267 , by inference, sumoylation facilitate basal thermotolerance through processes that are SA independen

268 unusual in that it not only fails to develop thermotolerance to 45 degrees C after acclimation at 38

269 bidopsis thaliana that are unable to acquire thermotolerance to high-temperature stress and have defi

270 Plants acquire thermotolerance to lethal high temperatures if first exp

271 ed that HSFA1a/HSFA1b/HSFA1d are involved in thermotolerance to mild heat stress at temperatures as l

272 The ability of organisms to acquire thermotolerance to normally lethal high temperatures is

273 Role of Rubisco Activase in imparting thermotolerance to the photosynthetic apparatus under hi

274 se upon sensing heat stress and thus, impart thermotolerance to the plants.

275 to hot temperatures), which is required for thermotolerance, uncovers a role of NO in thermotoleranc

276 BABA did not enhance basal thermotolerance under a severe heat-shock treatment.

277 phenotypic effects other than a decrease in thermotolerance under both photoautotrophic and photomix

278 Increased thermotolerance was also not observed in C3-dominated co

279 The role of ABA in BABA-induced thermotolerance was complex.

280 This thermotolerance was dependent on heat shock protein 101,

281 Thermotolerance was increased by proline or tryptophan s

282 n of HsfA2 in heat stress response (HSR) and thermotolerance was investigated in different tissues of

283 Development of thermotolerance was not associated with Akt or ERK1 and

284 In contrast, thermotolerance was not attainable in hsf1(-/-) cells, a

285 BABA-enhanced thermotolerance was partially compromised in the ABA-ins

286 A similar induction of hsps and thermotolerance was seen with another proteasome inhibit

287 ionally important for innate and/or acquired thermotolerance, we combined the use of a barcoded pool

288 tify molecular events important for acquired thermotolerance, we compared viability and transcript pr

289 interact with HSP101 or that are involved in thermotolerance, we screened for extragenic suppressors

290 expressed in hsf1-m3 cells is sufficient for thermotolerance, we used heterologous promoters to regul

291 and salicylic acid in BABA-induced acquired thermotolerance were identified by mutant analysis.

292 Estimates of heritability of larval thermotolerance were low, but significant, and all life-

293 Nineteen variants with further improved thermotolerance were produced.

294 , 36 single site mutants exhibiting improved thermotolerance were produced.

295 Predicted growth-limiting factors for thermotolerance were validated through nutrient suppleme

296 ch do not make isoprene, exhibited increased thermotolerance when isoprene was supplied in the airstr

297 Other short-chain alkenes also improved thermotolerance, whereas alkanes reduced thermotolerance

298 SKR-4, and SKR-5 act redundantly to promote thermotolerance with CUL-6.

299 Endogenous SA correlated with basal thermotolerance, with the SA-deficient NahG and SA-accum

300 At 38 degrees C, GCP acquire thermotolerance within 24 h, but their expansion is limi