ライフサイエンスコーパス: thorough

1 A thorough analysis by (19)F NMR and ESI-MS revealed the n

2 A comprehensive and thorough analysis demarcated GLI3 presence in the bindin

3 From a thorough analysis of a large volume of individual molecu

4 merous benefits associated with conducting a thorough analysis of fusion events within cancer samples

5 Here we provide a thorough analysis of nucleic acid complexes containing e

6 In this review, we depict a thorough analysis of our present knowledge on different

7 gh first proposed more than 20 years ago, no thorough analysis of reliability or reproducibility of t

8 This resistance prompted a thorough analysis of the canine PRNP gene and the presen

9 This system allows for thorough analysis of the enzymatic process through monit

10 However, a thorough analysis of the role for Gle1 self-association

11 We herein report the first thorough analysis of the structure-permeability relation

12 some of these interactions, but we present a thorough analysis using the wing disk epithelium to show

13 We present here a thorough and complete analysis of mouse P0-P140 prethala

14 re conserved in the zebrafish, and provide a thorough and complete description of trunk lymphatic ves

15 ation, and replication analysis-to provide a thorough and comprehensive analysis of a synthetic chrom

16 mediation and agricultural production, but a thorough and mechanistic assessment of efficacy and safe

17 eatment alternative in select patients after thorough and objective assessments, particularly if they

18 TRO guideline, published in 2016, are clear, thorough, and based on current scientific evidence.

19 lines, published January 9, 2019, are clear, thorough, and based on the most relevant scientific evid

20 the guideline, published in 2016, are clear, thorough, and based on the most relevant scientific evid

21 TRO guideline, published in 2017, are clear, thorough, and based on the most relevant scientific evid

22 es for Prostate Cancer guideline were clear, thorough, and based on the most relevant scientific evid

23 espite an emerging role in human diseases, a thorough annotation of human viral transcriptional regul

24 Thorough antibiotic allergy history collection can be a

25 A thorough appreciation of the strengths and weaknesses of

26 Here, a thorough approach to characterizing diverse metabolites-

27 for ordering a test are the desire to be as thorough as possible (71% [n = 422]) and insurance cover

28 e common in persistent childhood asthma, and thorough assessment of allergy is crucial for optimal ca

29 mics has increased, although often without a thorough assessment of analytical strategies applied to

30 Our work provides a novel structure, a thorough assessment of druggability and robust screening

31 pulmonary exercise testing (CPET) provides a thorough assessment of exercise integrative physiology i

32 Our data provide for the first time a thorough assessment of Spartin loss effects, including i

33 iated chain, which was made possible after a thorough assessment of the ethical issues and the impact

34 There is a need for a thorough assessment of the potential tag effects on smal

35 A thorough assessment of their impact has been hampered by

36 Thorough assessment of transgenic (Tg) mouse lines that

37 These findings, based on a thorough biophysical and thermodynamic analysis of PaaR2

38 At higher SAW intensity, we find immediate, thorough, but temporary paralysis of the worms.

39 to prevent progressive disease, founded in a thorough cellular and molecular understanding of the imm

40 We recommend that a thorough characterisation of nasal delivery devices and

41 ndings underscore the critical importance of thorough characterization and validation of any modified

42 However, a thorough characterization of AVP and OT-immunoreactive (

43 In this work, to give a thorough characterization of historical gilt silver thre

44 many of these limitations, including a more thorough characterization of intersubunit interfaces.

45 early diagnosis, prognosis, or relapse and a thorough characterization of intratumor heterogeneity an

46 highly valuable tool for the generation and thorough characterization of libraries of related peptid

47 We performed a thorough characterization of myofiber pathology in mdx m

48 ures for drowsy driving in nurses requires a thorough characterization of nurse's perceptions of drow

49 the N. meningitidis pathogen, thus enabling thorough characterization of outbreaks.

50 biotechnology, and food industry requires a thorough characterization of phage-host interaction on a

51 In situ X-ray diffraction and thorough characterization of solids obtained using gentl

52 ogenic inhibition of immune sensing requires thorough characterization of the HNSCC regulators of inn

53 Here we provide a thorough characterization of the STROBE system, demonstr

54 d standby-deficient tisB mRNAs, we provide a thorough characterization of the tisB standby site.

55 A thorough characterization, including synchrotron-based n

56 ility of the tetravalent complex enables its thorough characterization.

57 properties, such as electron affinities, by thorough choice of the aromatic blades that interact thr

58 schizophrenia underwent EAP, cognitive, and thorough clinical and functional assessment.

59 ch to diagnosis emphasises the importance of thorough clinical and laboratory evaluations to exclude

60 Care Guideline, published in 2016, is clear, thorough, clinically practical, and helpful, despite the

61 is possible towards either direction, after thorough, collective, evaluation of changes in the above

62 A thorough comparative analysis has been performed with fi

63 This thorough comparison also indicates compounds linked to t

64 Here, we conducted a thorough comparison of CO(2) budgets at multiple scales

65 ct annotation of these sequences; however, a thorough comparison of the performance of these tools ha

66 A thorough computational study has been carried out to und

67 Thorough consideration of these factors could have a pos

68 n of multiple sclerosis lesions, including a thorough definition and illustration of typical MRI feat

69 roach that combines parentage analysis and a thorough dendrophenotypic characterisation of putative p

70 The mechanisms are considered in light of thorough density functional theory (DFT) calculations.

71 In vivo, thorough depletion of nonmuscle myosin II delayed furrow

72 We provide the most thorough description of paediatric Zika to date.

73 a particular focus on recent designs, and a thorough description of the functions performed by these

74 sses at stake, our results open the way to a thorough description of the hydrodynamic interactions be

75 We provide a thorough description of the ligand unbinding pathway ide

76 Nramp in multiple conformations to provide a thorough description of the Nramp transport cycle by ide

77 Here, we present a thorough description of the potent, nanomolar inhibitor

78 tous Ce(4+) ion, are exceptionally rare, and thorough, detailed characterization in these systems is

79 A thorough diagnostic evaluation is essential to determine

80 dence is rising in persons under age 50, and thorough diagnostic evaluation of young persons with sus

81 2019;000(00):000-000) present a thorough discussion of methodological challenges when es

82 ideration of their prevalence and magnitude; thorough discussion of the potential for unknown confoun

83 ocatalytic nitrogen reduction, followed by a thorough discussion of various experimental parameters.

84 This review will provide a thorough discussion on designing nano-barcodes, focusing

85 n to the most recent advances, and present a thorough discussion on non-trivial structural and electr

86 l observation may be considered only after a thorough discussion with patients about the potential ri

87 m Breslow thickness with ulceration) after a thorough discussion with the patient of the potential be

88 have been avoided with careful examinations, thorough documentation in the patients' charts, and deta

89 are relatively new electrode materials, and thorough electrochemical characterization is still missi

90 r natural substrates are sparse, calling for thorough enzyme structure-function studies.

91 rt communication report, we herein present a thorough evaluation of a green Fmoc removal protocol.

92 ere, R1441C and G2019S knock-in mice enabled thorough evaluation of dendritic spines and synapses on

93 A thorough evaluation of limb perfusion is important in th

94 hallenges, there is a pressing need for more thorough evaluation of model predictions to guide invest

95 t to postpone donation a few days to allow a thorough evaluation of organ damage following cardiac ar

96 fertility, which underscores the need for a thorough evaluation of patients to identify treatable or

97 rate of the Accula POC test calls for a more thorough evaluation of POC test performance characterist

98 This review provides a thorough examination and critical evaluation of contempo

99 herapeutic chaperone modifications without a thorough examination of cofactor relationships.

100 A thorough examination of functional changes in gastric mo

101 it is prudent that these patients undergo a thorough examination of their vergence and accommodative

102 Thorough examples relevant to nutrition researchers are

103 In this review, we guide the reader thorough experimental description of PEEM as a character

104 as some potential limitations that warrant a thorough experimental examination of its validity.

105 organocatalysts is generally carried out by thorough experimental screening of different candidates.

106 For researchers dedicated to the cause, thorough experimental standards at the bench, in the cli

107 nd analytical studies fall short in giving a thorough explanation to particle equilibrium states.

108 ers may be inclined to suggest CTE without a thorough exploration of comorbid factors that demonstrat

109 Thorough exploration of sources of heterogeneity is key

110 rt highlights the importance of performing a thorough eye examination, which includes double eversion

111 sent a new comparative genome analysis and a thorough genetic analysis of SSV1 using both specific an

112 derline the importance of an early-stage and thorough genetic assessment in paediatric patients with

113 Thorough genetic investigation emphasizing sequencing te

114 Finally, a more thorough genomic analysis was performed, using CRISPR-Ca

115 Best Practice Advice 2: Thorough histological analysis of duodenal biopsies with

116 The need for a thorough history and a validated questionnaire to identi

117 Patients were evaluated by a thorough history and ophthalmic examination with selecte

118 tures prior to antimicrobial administration, thorough history for IVDA, and caution with premature di

119 Clinicians must continue to conduct thorough history-taking and examination and make judicio

120 be based just on size, but a combination of thorough hormonal evaluation and imaging characteristics

121 , this fusion of the data allowed for a more thorough identification and mapping of the painting's co

122 level (T4), public awareness campaigns need thorough impact assessment.

123 Our results illustrate the need of early, thorough in vivo characterization of ADC candidates.

124 orrect assignment of Grade requires nuanced, thorough interpretation of a broad array of findings by

125 sion arising from F8BT membrane lattices was thorough investigated, highlighting a non-Lambertian pho

126 he lack of integrated diagnostic tools for a thorough investigation at complementary length scales.

127 ients are discussed, underlining the need of thorough investigation for an effective design of mHealt

128 Thorough investigation for cryptococcal disease with LPs

129 A thorough investigation has enabled the optimization of t

130 dden unexplained death cohort that underwent thorough investigation in the United States' largest med

131 This prompted a thorough investigation of AAG-catalyzed excision of eG f

132 Thus, a more thorough investigation of beta-HPV biology is warranted.

133 teins in filarial worms and encourage a more thorough investigation of clade- and parasite-specific f

134 This more thorough investigation of GW296115 has confirmed it as a

135 Thorough investigation of nitridophosphates has rapidly

136 toolbox provides an advanced platform for a thorough investigation of the 190 possible WNT/FZD pairi

137 Thorough investigation of the Dy(III) congener through b

138 mitochondrial genomes coevolved will need a thorough investigation of the hundreds of mitonuc genes,

139 Combined with a thorough investigation of the local membrane structure,

140 However, thorough investigation of this phenomenon is hampered by

141 This thorough investigation of uranium uptake in sea urchin i

142 In this context, a thorough investigation of virus-host interactions is cri

143 al-organic frameworks (MOFs) have been under thorough investigation over the past two decades, photoc

144 o define the critical structural features, a thorough investigation was performed on representative p

145 gy and its molecular mechanisms require more thorough investigation.

146 gene is not fully understood and requires a thorough investigation.

147 therapeutic potential that warrants further thorough investigation.

148 Consequently, thorough investigations of siRNA absorption, distributio

149 Thorough investigations of these reactions have identifi

150 rify inhibition of the studied isozymes by a thorough kinetic analysis.

151 e of caspase-7 bound to a fragment hit and a thorough kinetic characterization of a zymogenic form of

152 puzzling activation using a novel activator, thorough kinetic investigation, and mutagenesis studies.

153 process or successfully design a new one, a thorough knowledge is required about the physicochemical

154 A thorough knowledge of the SR X-ray sensitivity of each c

155 Although a thorough literature review was performed for each topic,

156 Together, these studies represent the most thorough mapping of multiple QTL types in a highly disea

157 A thorough mechanistic insight of the reaction is proposed

158 he aim of the present review is to provide a thorough mechanistic overview of NCL and extended method

159 Thorough mechanistic understanding allowed for this high

160 ogy and climate forcing, yet we still lack a thorough mechanistic understanding of these responses.

161 Diagnosis relies on a thorough medical and occupational history, functional as

162 BEST PRACTICE ADVICE 4: Thorough medication histories should be collected from p

163 se friend or family member, in addition to a thorough mental status examination by a clinician to del

164 Clinicians need to ensure early and thorough metabolic control for all patients affected by

165 Here, we describe a thorough molecular and biochemical analysis of a mutant

166 This study shows that thorough molecular characterization of treatment-resista

167 A thorough molecular workup of 1 of the cases with early r

168 A thorough notion of FC promises better understanding of v

169 women, stress the importance of eliciting a thorough obstetrical and gynecological history during ca

170 n's disease in children is recommended, with thorough ongoing assessments to define treatment success

171 Thorough optimization of the activation/cyclization resu

172 is a complex imaging technique that requires thorough optimization of various experimental parameters

173 A thorough overview is undertaken, from the seminal studie

174 A thorough parameter optimization led to a maximum methane

175 ix tool can accelerate model spin-up, permit thorough parametric sensitivity tests, enable pool-based

176 umulated in the urinary tract, thus allowing thorough pelvic exploration.

177 ove our understanding of AD biology, conduct thorough pharmacokinetic and pharmacodynamic analyses, d

178 We conducted a thorough phenotypic evaluation of CIV-H3N2 in order to a

179 A thorough physical characterisation of the particles incl

180 tial impacts of a similar future eruption, a thorough physical understanding of the YWAS is crucial.

181 copper-oxygen species but seeks to provide a thorough picture of the spectroscopic characteristics an

182 Thorough preclinical target validation is essential for

183 clinical practice is hindered by the lack of thorough preclinical testing using representative animal

184 the optical basis of lens platforms used and thorough preoperative planning to aid decision making.

185 Thorough quality assessment of novel interactions identi

186 microscopic model organisms to facilitate a thorough quantification of shape differences within and

187 Along this path, through a thorough quantitative analysis we approach connectivity

188 tive differential proteomics, we performed a thorough quantitative inventory of the protein compositi

189 To gain a more thorough quantitative understanding of the factors that

190 Therefore, thorough removal of potentially toxic cryoprotective age

191 the early description of Kraepelin were more thorough, reporting a mean of 16.6 of these characterist

192 in the study: 70 IBD and 415 NIC based on a thorough review of colonoscopy, pathology and clinical r

193 A thorough review of the available evidence suggests the a

194 increased adiposity in adults and provide a thorough review of the evidence that will empower health

195 The purpose of this document is to provide a thorough review of the existing evidence on HIV-associat

196 An efficient and thorough review of the existing literature is crucially

197 Finally, we provide a thorough review of the literature to reconcile differenc

198 Despite this, a thorough review of the specific methods of synthesis of

199 Thorough review was performed in a blinded fashion by an

200 In this work, we provide thorough reviews and discussions on the statistical meth

201 r tests is necessary, but not sufficient for thorough sampling.

202 A thorough search strategy was applied to identify randomi

203 We also carry out thorough sensitivity analysis to define the robustness o

204 We conduct thorough simulation studies to verify the proposed metho

205 By a thorough single-crystal inelastic neutron scattering stu

206 A thorough solution-state spectroscopic characterization,

207 In addition, a thorough spectroscopical study permitted to determine th

208 The present review provides a thorough state-of-the-art overview on the use of biologi

209 merase chain reaction (RT-qPCR) assays and a thorough statistical analysis was conducted for the RT-q

210 These studies underscore the importance of a thorough stepwise approach, including consideration of t

211 e complexes for WT and DM, together with the thorough structural analyses presented herein, we propos

212 In our thorough structural and biophysical analyses, we have fo

213 c acids catalysts has been made by providing thorough structural fundaments (e.g. first structure of

214 Thorough structure-activity relationship studies of 3,5-

215 r natural substrates are sparse, calling for thorough structure-function studies.

216 A thorough study of relevant reaction parameters revealed

217 A quantitative and thorough study of skin permeation is essential for chemi

218 at the use of ISF data, when combined with a thorough study of the fragmentation mechanisms, constitu

219 A thorough study of the reactivity of the ortho-amide func

220 Our lipidomic analysis is the most thorough such study of the Fatp4(-/-) mouse skin barrier

221 etion of the Rb checkpoint protein, but more thorough suppression of the transcriptional and cell cyc

222 Significant preparation will be needed for a thorough, synchronized, and full withdrawal of OPV, and

223 Thorough systemic and ocular investigations are critical

224 entorhinal cortex (MEC) has been subject to thorough testing and analysis, and many theories for the

225 Thorough theoretical calculations support the observed e

226 Herein we describe a thorough thermochemical analysis of the (de)hydrogenatio

227 entative sites around the world to conduct a thorough thermodynamic analysis of aerosol pH and its se

228 mono-MAs to enzymolysis suggests a need for thorough toxicity evaluations of these intermediate comp

229 To unravel their connection, thorough transcriptional, epigenetic, and functional cha

230 ction by several hundred percent, and thus a thorough treatment of uncertainty is essential.

231 l Stem Cell, Schiroli et al. (2019) report a thorough, unbiased investigation of the impact of gene e

232 A thorough uncertainty analysis indicated a relative stand

233 To achieve optimal results, a thorough understanding about the different implementatio

234 er, more broadly protective vaccines, a more thorough understanding is needed of how antibodies that

235 A more thorough understanding is needed to develop treatments a

236 ronics and light harvesting (8-16) require a thorough understanding of (nanoscale) heat flow.

237 , our findings highlight the importance of a thorough understanding of a species' movement and space

238 A thorough understanding of Acinetobacter baumannii pathog

239 P inhibitors might certainly be warranted, a thorough understanding of all associated toxicities is i

240 Thorough understanding of core-shell formation is critic

241 However, a thorough understanding of CTCs associated with breast ca

242 omising immunotherapeutic platform demands a thorough understanding of how cell death induced in the

243 ng the RCL sequence, and will require a more thorough understanding of how conformational dynamics ac

244 Developing a thorough understanding of how ectotherm physiology adapt

245 miology that should always be enveloped by a thorough understanding of how systems and the social exp

246 A more thorough understanding of how these pharmacological agen

247 for vaccine development and cultivate a more thorough understanding of IAV evolution and persistence

248 mechanics of this material has facilitated a thorough understanding of its properties at various leve

249 applied settings, such as rehabilitation, a thorough understanding of its underlying mechanisms is r

250 G protein-coupled receptors (GPCR) requires thorough understanding of ligand binding and mechanism o

251 demand high efficiencies, specificity, and a thorough understanding of likely editing outcomes.

252 A thorough understanding of malaria vector species composi

253 opment of targeted cancer therapy requires a thorough understanding of mechanisms of tumorigenesis as

254 However, a thorough understanding of physicochemical properties tha

255 A thorough understanding of reproductive processes is nece

256 A thorough understanding of RNAP and transcription factor

257 A more thorough understanding of sex-specific cardiovascular di

258 ms play a role in defining these subtypes, a thorough understanding of the biological mechanisms is l

259 Hence, a thorough understanding of the biology of the mTOR axis i

260 These findings provide a thorough understanding of the biosynthesis pathway, spat

261 A thorough understanding of the criticality of N325 deamid

262 l potential of high-throughput sequencing, a thorough understanding of the data produced as well as t

263 A thorough understanding of the determinants of the infect

264 the furnish during processing, necessitating thorough understanding of the dewatering behavior referr

265 Though this fold is common, we do not have a thorough understanding of the different ways viruses ada

266 A thorough understanding of the effects of population gene

267 mprehensive understanding of bone requires a thorough understanding of the genetic basis of bone trai

268 A thorough understanding of the important determinants of

269 le types of steric and electronic effects, a thorough understanding of the interplay of these underly

270 table lipid-polymer hybrid system requires a thorough understanding of the material properties and th

271 A thorough understanding of the mechanism of action could

272 A thorough understanding of the mechanism of this efficien

273 Thorough understanding of the mechanisms involved in the

274 Moreover, we currently lack a thorough understanding of the mechanisms of humoral immu

275 Thus, a thorough understanding of the mechanisms that regulate D

276 Overall, a thorough understanding of the mechanistic principles gov

277 A thorough understanding of the nuances, strengths, and li

278 NA's generative mechanism, AR enables a more thorough understanding of the origins of fCNAs.

279 Hence, thorough understanding of the pathophysiological mechani

280 applications may be greatly facilitated by a thorough understanding of the principles that underlie t

281 ew models being proposed, and has provided a thorough understanding of the properties of existing mod

282 ally, mechanistic studies resulted in a more thorough understanding of the reaction, giving rise to t

283 A thorough understanding of the role of human immunodefici

284 riable conversion efficiencies and a lack of thorough understanding of the signaling pathways directi

285 l microscopy requires careful planning and a thorough understanding of the technique.

286 Therefore, a thorough understanding of the vascular anatomy of the AV

287 A thorough understanding of thermosensation not only provi

288 A thorough understanding of these mechanisms will contribu

289 ith complement-mediated responses, and thus, thorough understanding of these molecular pathways is ne

290 determining device efficiencies; however, a thorough understanding of these processes is hindered by

291 A thorough understanding of this pathogen's physiology and

292 e range of tissues and cell types requires a thorough understanding of viral adaptation and infection

293 on from purified components, and thus a more thorough understanding.

294 sophisticated bioinformatics approaches and thorough validation in diverse patient samples and popul

295 inical testing of new anti-fibrotic drugs, a thorough validation of micro-computed tomography (CT) in

296 Statistical modeling of measurements and thorough validation of structural assignment using liqui

297 With thorough validation, quantification of inherited genetic

298 A thorough visual inspection of the thoracic MR-AC map and

299 classify examinations and probably the most thorough way to automatically analyze corneal topography

300 A thorough X-ray crystallographic study depicted their bin