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1 ction of NFkappaB (five-fold) and cyclin D1 (three-fold).
2 of thromboembolic complications some two to three fold.
3 e median survival of TET1-high AML mice over three fold.
4 iltered and reabsorbed glucose up to two- to three-fold.
5 ed in EC hyperproliferation, increased IL-32 three-fold.
6 n findings, based on resting-state fMRI, are three-fold.
7 l plasma membrane to cytoplasmic H(+)-ATPase three-fold.
8 lated a TGF-beta reporter construct promoter three-fold.
9 the overall incidence of respiratory failure three-fold.
10 tivity by increasing the sensing area almost three-fold.
11 ing examination increased the risk of an IBC three-fold.
12 up to six-fold, and its cell volume by about three-fold.
13 the hit frequency from the chemical library three-fold.
14 Case rates differed four-fold and mortality three-fold.
15 ), thus increasing the detection sensitivity three-fold.
17 he objective of this retrospective study was three fold: 1) to determine whether a gene signature ass
18 e contributions of the proposed approach are three-fold: 1) We consider all possible genotype models
20 bloodstream infection increased by more than three-fold after the second dressing disruption and by m
24 that distinguishes between nearly identical three-fold and quasi-three-fold sites of the icosahedral
25 reased fluorescence intensities from two- to three-fold and similar decreases in lifetimes were obser
26 talyzed CO evolution systematically rises by three-fold and the specific activity for catalyzed H2 ev
27 p < 0.05) than of FQ and FW by approximately three-fold and two-folds against Caco-2 and MCF-7 cell l
28 at increased the incidence of ARDS by nearly three-fold and was associated with more severe nonpulmon
29 fold, monocyte vitamin D receptor expression three-fold, and 24-hydroxylase expression; therapy decre
30 n plant transcription factor interactions by three-fold, and reveals previously unknown family-specif
32 lso show that charged residues at the fibril three-fold apices provide the majority of the binding fr
33 conditions that enhance neurite outgrowth by three-fold as compared to unstimulated or wild-type (WT)
35 topes on or near protrusions surrounding the three-fold axes, raising the possibility that AAV-2 migh
36 o those of mammalian TRICs and implicate the three-fold axis in the allosteric regulation of the chan
37 identified a CTD-CTD interface at the local three-fold axis in the cryoEM map and confirmed its func
38 The location of the epitope close to the three-fold axis is consistent with the previous analysis
39 rms a large portal-like assembly at a unique three-fold axis of symmetry, following receptor engageme
40 also identified subunit interactions at each three-fold axis of the capsid that are maintained throug
41 three separate protrusions surrounding each three-fold axis, and a channel at each five-fold axis.
45 on the alkynyl bonds enabled a copper-free, three-fold azide-alkyne cycloaddi-tion at 50 degrees C.
46 ow pump fluence of ~ 800 nJ cm(-2), at least three-folds better than previously reported values among
47 of bleaching-level thermal stress increased three-fold between 1985-91 and 2006-12 - a trend climate
48 s of Hhex(-/-) mice were elevated as much as three-fold between E9.5 and E11.5, and treatment of cult
51 analysis reduced these variations as much as three-fold, but only within a narrow range of focus and
55 rating action of HCO3(-) is slowed more than three-fold by the carbonic anhydrase inhibitor acetazola
56 arget for chemoprevention, was induced about three-fold by the RARalpha-selective agonist Am580, in T
58 roduces actuation strains of up to 45% and a three-fold chemical amplification of the controlling lig
65 nt is found to increase the transconductance three-fold, contact resistance is not found to be the do
67 n a randomized study to be associated with a three-fold decrease in arterial rupture in vascular EDS
70 intestinal deletion of the HuR gene caused a three-fold decrease in tumor burden characterized by red
71 finity of semaglutide (0.38 +/- 0.06 nM) was three-fold decreased compared to liraglutide, whereas th
72 attesting that the canting spin stripes are three-fold degenerate states akin to helices and the mul
75 accuracies in current BPLM theory, including three-fold discrepancies in torsional persistence length
78 ge of 25 to 1,000 mg, and there is a 1.5- to three-fold drug accumulation at steady-state after once-
79 pecifically, our 60 vol.% Ap-SFRP displays a three-fold elevation in tensile and flexural strength, a
83 which spectrin is able to undergo a seamless three-fold extension while remaining a linear filament,
89 as a serum creatinine increase greater than three-fold from baseline, or greater than or equal to 4.
90 rum creatinine increase greater than two- to three-fold from baseline; stage 3 as a serum creatinine
91 opolymer could extend ibuprofen release over three-fold (from 3days to >9days) whilst the release of
92 m 15 mg to 60 mg, resulting in a two-fold to three fold gradient of mean trough drug exposure (16.0-4
93 =1.5 hrs from the health centre had a two to three fold greater risk of death than children who lived
94 of infections during the exposure period was three-fold greater (adjusted hazard ratio [AHR], 2.93; 9
96 major phenolic acid in pigmented rice, being three-fold greater in bound form than in soluble form.
97 The unadjusted mortality rate was nearly three-fold greater in the acute lung injury group (23.9%
99 rom a low-elevation provenance had more than three-fold greater recruitment to their third year than
100 in efficiency of lift production is at least three-fold greater than reported for other insects.
102 rtial thromboplastin times that were two- to three-fold greater than those observed in saline-infused
103 d larvae maintained chemical defenses nearly three-fold greater than those of siblings reared in stre
104 or by bath hypotonicity, were approximately three-fold greater when positioned next to intercalated
105 and anabolic activity (apposition rate) were three-fold greater, calcified spongiosa decreased by two
106 d that the adhesion forces were about two to three fold higher in the calcium ion deficient fluids co
107 d higher concentrations of bound phenols and three-fold higher concentrations of lignin phenols than
108 oral loss was lower (- 34%), probably due to three-fold higher daily water temperature variability th
110 ed tomography at their 3-month follow-up had three-fold higher frequencies of CD8 T cells expressing
111 n liberation and in vitro accessibility were three-fold higher from spinach puree compared to whole l
115 yr), the prevalence of CKD was approximately three-fold higher in those with a history of hip fractur
116 R haplotype is responsible for an average of three-fold higher insulin expression than class I VNTR i
117 t 60% of the tested primary NSCLC tumors had three-fold higher JNK2 protein and two- to three-fold hi
118 d three-fold higher JNK2 protein and two- to three-fold higher JNK2alpha mRNA expression than normal
119 six-fold higher neutrophil infiltration and three-fold higher level of myeloperoxidase activity than
120 ributable to tobacco smoking rather than the three-fold higher prevalence of oral HPV infection in th
121 ses show that the G allele confers a two- to three-fold higher promoter activity and stronger binding
122 als with two APOL1 risk alleles had a nearly three-fold higher risk for ESRD compared with those with
123 f variation of respiratory rate had a nearly three-fold higher risk of extubation failure, and when t
126 nd a limit of detection of 1pg/ml, which was three-fold higher than aptamer alone sensor for PSA.
128 rexpressing plants was found to be more than three-fold higher than that of wild-type, but again the
129 HGF levels in obese subjects were more than three-fold higher than those of lean subjects (2,462 +/-
131 ne, and Mg/adenosine and lidocaine group had three-fold higher urinary output (2.1 mL//kg/hr [95% CI,
132 estational day 16, term = 22--23 days) had a three-fold higher UtBF compared to non-pregnant animals.
133 se per 1-SD higher log(e) CRP concentration (three-fold higher) were 1.63 (95% CI 1.51-1.76) when ini
135 two-fold (HR, 1.94; 95% CI, 1.72, 2.18) and three-fold (HR, 3.05; 95% CI, 2.38, 3.90) higher risk of
137 a protein in unstressed leaves but increased three-fold in leaves exposed to elevated temperatures fo
138 one; (2) more genes are upregulated at least three-fold in response to Eyeless+signaling factors comp
141 umber of IL-4-producing CD4+ cells increased three-fold in the trauma patients compared with healthy
143 ontrols without bipolar disorder indicates a three-fold increase (risk ratio [RR] 3.22 [95% CI 2.41-4
144 finding rate was 1.9 patients/month nearly a three-fold increase compared with our historical control
145 ited a long circulation half-life of ~45h, a three-fold increase from the unmodified native version,
148 at mice heterozygous for the mutation have a three-fold increase in basal protein kinase G (PKG) acti
149 rom n- to p-type, accompanied by a more than three-fold increase in carrier mobility, up to muh appro
150 rea, the Janus catalyst exhibits a more than three-fold increase in catalytic efficiency compared to
152 erved during micellization, for which only a three-fold increase in ClO4(-) concentration was necessa
153 e-CPP, Tat-induced GT-tg mice demonstrated a three-fold increase in cocaine-CPP over the response of
155 rrying versus tumor-free mice, we observed a three-fold increase in differentially expressed miRNAs.
157 d be impacted by dynamic flooding by 2100; a three-fold increase in exposed population than if only S
158 amate receptor agonist that causes a two- to three-fold increase in hypocotyl elongation on Arabidops
159 mechanical ventilation was associated with a three-fold increase in in-hospital mortality (36% vs. 10
161 d, as in the circulation, but demonstrated a three-fold increase in KIR expression compared with NKG2
162 cimens, 4 + 3 cancers were associated with a three-fold increase in lethal PCa compared with 3 + 4 ca
163 micromol/kg intraperitoneally) resulted in a three-fold increase in leukocyte adhesion, compared with
165 the presence of target muscle cells causes a three-fold increase in NO production by macrophages, wit
166 a few hours after UV, we show an approximate three-fold increase in recombinants in the TLS mutants o
167 t the highest decile of risk had a more than three-fold increase in risk of melanoma compared with th
168 he hemisphere ipsilateral to the hematoma, a three-fold increase in the concentration of glycine was
169 nd provides significant stabilization with a three-fold increase in the intermolecular nonbonded inte
170 les of estradiol demonstrated greater than a three-fold increase in the mortality rate for the highes
171 of non-smokers is associated with a two- to three-fold increase in the odds of developing periodonti
172 Staff-initiated CPR was associated with a three-fold increase in the odds of hospital discharge an
174 e waiting list was associated with an almost three-fold increase in the RR for death for patients wit
175 s in tumor burden in Smad3(+/-) mice, with a three-fold increase in TLR7 expression compared to contr
176 first year of life, infants have an overall three-fold increase in weight, while the fetus develops
177 highest F1-V protein accumulation, almost a three-fold increase of F1-V protein levels in fruit than
178 P groups, but P. gingivalis LPS1690 showed a three-fold increase on IL-10 production in the NP group
180 result the particle transport experienced a three-fold increase when compared with the traditional s
181 ome peripheral blood mononuclear cells had a three-fold increased ability to differentiate into fibro
182 on of both CKD and MAC was associated with a three-fold increased risk for death compared with those
184 2% allele frequency in controls that confers three-fold increased risk of ALL in children of European
186 admission was independently predictive of a three-fold increased risk of delirium (odds ratio 3.1 [1
190 s of liver tumor formation revealed striking three-fold increases in tumor burden in Smad3(+/-) mice,
191 ion we found significant (p < .0006) two- to three-fold increases in venous and arterial F2-isoprosta
192 tion of apoptotic hepatocellular death and a three-fold increment in the number of proliferating hepa
193 ucture of the tubular assembly shows, at the three-fold interface, a three-helix bundle with critical
194 with >/= 2 clinical conditions, there was a three-fold, inverse association between age and mean OHI
195 of ciprofloxacin resistance increased two to three-fold, irrespective of recent sexual contact overse
198 of rare variants, we estimate that a two- to three-fold larger cohort would provide 80% power to impl
201 le APOA5*3-defining allele (19W) resulted in three fold lower ApoAV plasma levels, consistent with ex
202 shows that it binds single-stranded DNA with three-fold lower affinity than ssRNA of the same length
203 vitellogenin mRNA 3'-UTR probe with a two to three-fold lower affinity than to a Drosophila dodecasat
204 te and bound to the c-myc CRD with a two- to three-fold lower affinity than to the vitellogenin mRNA
208 ugh F2-isoprostane levels were approximately three-fold lower in patients randomized to hypothermia v
211 structures generated from trisulfonates with three-fold molecular symmetry are the topological equiva
213 The encapsulated hUCMSCs synthesized nearly three-fold more bone minerals than the hBMSCs in vitro.
214 ng drug elution--near zero-order release was three-fold more efficient at depositing drug in the sten
216 tment or nontreatment, the post-PET plan was three-fold more likely to lead to treatment than nontrea
217 Cs formed 70% larger bone nodules containing three-fold more mineralized bone compared with long-bone
218 wever, in the long-term animals, two-fold to three-fold more new bone width (</= 0.004) was seen arou
220 uding differential up- and down-regulation (>three folds) of eight flowering time-associated genes (i
221 biomass in the nutrient-rich crust increased three-fold one week after watering, whereas it did not c
224 estricted rats, Cp mRNA expression increased three-fold (P < 0.01) and protein expression increased 1
225 exposure increased the k3-tidal strain slope three-fold (p = 0.009), without significant lung edema.
226 in-treated net significantly reduced (nearly three-fold, p<0.0001) culicine landings inside enclosure
228 g properties of catalytic Pd on-top sites vs three-fold Pd hollow sites and is therefore of major rel
230 ution, suggest that critical residues at the three-fold protrusion and at the interface of the five-f
231 a conformational epitope at the vertex of a three-fold protrusion on the viral surface, thereby simu
236 of the eccentric contractions varied over a three-fold range and overlapped with that of the isometr
237 omen shows a similar tendency with an almost three fold reduction in the probability to have a Down s
238 These experiments reveal an approximately three-fold reduction in activation energy for ion transp
239 ,25(OH)(2)D(3) levels were associated with a three-fold reduction in FGF23 levels that were increased
240 rapy results in central tumor necrosis and a three-fold reduction in human tumor vascular density.
242 validate our approach and show it produces a three-fold reduction in working space when constructing
243 levels of catalase in the brain resulting in three-fold reductions in inflammation and complete neuro
244 erapy samples may increase power to detect a three-fold reservoir reduction by 15 to 24 percentage po
250 k of developing bipolar disorder (BD), and a three-fold risk of developing major depressive disorder
252 of localized spin-orbit polarons (SOPs) with three-fold rotation symmetry nucleated around single S-v
253 NMR spectroscopy, we determined a symmetric three-fold rotational potential with a barrier of 10.2 k
254 ctroscopy, show that the molecule exhibits a three-fold rotational symmetry and adopts a folded confo
255 into a novel superstructure with unexpected three-fold rotational symmetry in a single two-dimension
257 he octahedral symmetry of the ligand and the three-fold rotational symmetry of the TolC entrance dete
259 maps reveal an energy- and doping-dependent three-fold rotational-symmetry breaking of the local den
262 A analogues were chemically synthesized; all three folded significantly faster in the glutathione-bas
266 ife of approximately 40 hours, approximately three-fold steady-state accumulation, dose-proportional
267 nd torsional behaviors; Z-DNA to be at least three-fold stiffer than random-sequence dsDNA, with a ne
271 e-directed, catalyst-assisted synthesis of a three-fold symmetric, extended pyridinium-based, cage-li
273 parin (LMWH) binds to Abeta40 fibrils with a three-fold-symmetric (3Q) morphology with higher affinit
276 the icosahedral virus surface, 60 with quasi-three-fold symmetry and 20 coincident with the icosahedr
278 n NMR data show that the protein has regular three-fold symmetry and undergoes localized structural c
279 al-binding site previously identified on the three-fold symmetry axis of a hexameric enzyme, LarE fro
280 ment, with carbonyl O atom positioned on the three-fold symmetry axis of the NH3(+) group (angle C(ep
283 imately 5-7 A M35-M35 distance in the fibril three-fold symmetry structure is likely to relate to M35
285 molecular machine through twelve-, six- and three-fold symmetry, and provides insights into molecula
289 ophic chondrocyte zone in the cKO-mice was > three-fold thicker than that in the age-matched control,
290 vaccine approach, HAd-H5HA vaccine induced a three-fold to eight-fold increase in HA-518-epitope-spec
295 oindolinone to the target structures are the three-fold use of ruthenium catalysts, first in azepine
297 the CDDP IC(50) and increased cell survival three-fold, while attenuating AXL in overexpressing cell
298 ond post-transplantation rituximab increased three-fold with each V allele (robust z = 2.08, P = .038
300 nces to the tumors of HCC-bearing mice about three-fold without a parallel increase in normal tissues