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1 ings secreted by/anchored to ECs (thrombotic thrombocytopenic purpura).
2 plasma metalloprotease, leads to thrombotic thrombocytopenic purpura.
3 ances) in the pathogenesis of chronic immune thrombocytopenic purpura.
4 basis for a common bleeding disorder, immune thrombocytopenic purpura.
5 severe, acute and chronic refractory immune thrombocytopenic purpura.
6 e are many definitions for refractory immune thrombocytopenic purpura.
7 splenectomy in patients with chronic immune thrombocytopenic purpura.
8 n used to treat patients with chronic immune thrombocytopenic purpura.
9 -cleaving metalloprotease, causes thrombotic thrombocytopenic purpura.
10 is and targeting treatment of chronic immune thrombocytopenic purpura.
11 management of pregnant patients with immune thrombocytopenic purpura.
12 ne may not be sufficient to cause thrombotic thrombocytopenic purpura.
13 MTS13 activity in plasma leads to thrombotic thrombocytopenic purpura.
14 the diagnostic approach to childhood immune thrombocytopenic purpura.
15 rategies employed in the treatment of immune thrombocytopenic purpura.
16 er clarify its role in idiopathic thrombotic thrombocytopenic purpura.
17 and in an IFN-gamma-enhanced model of immune thrombocytopenic purpura.
18 be treated for these infections, not immune thrombocytopenic purpura.
19 ective means of treating acquired thrombotic thrombocytopenic purpura.
20 arin-induced thrombocytopenia and autoimmune thrombocytopenic purpura.
21 much platelet adhesion may cause thrombotic thrombocytopenic purpura.
22 refractory and relapsing cases of thrombotic thrombocytopenic purpura.
23 hophysiology differs from that of thrombotic thrombocytopenic purpura.
24 refractory and relapsing acquired thrombotic thrombocytopenic purpura.
25 iciency causes a lethal syndrome, thrombotic thrombocytopenic purpura.
26 cal hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.
27 ongenital and acquired idiopathic thrombotic thrombocytopenic purpura.
28 gG from a patient with idiopathic thrombotic thrombocytopenic purpura.
29 siology and current management of thrombotic thrombocytopenic purpura.
30 rophic microangiopathic disorder, thrombotic thrombocytopenic purpura.
31 g metalloprotease ADAMTS13 causes thrombotic thrombocytopenic purpura.
32 e illnesses also met criteria for thrombotic thrombocytopenic purpura.
33 large multimers, which may cause thrombotic thrombocytopenic purpura.
34 der clinically indistinguishable from immune thrombocytopenic purpura.
35 days or less before the onset of thrombotic thrombocytopenic purpura.
36 ained after splenectomy for trauma or immune thrombocytopenic purpura.
37 c hypoplasia but not in patients with immune thrombocytopenic purpura.
38 ease occur in patients with acute thrombotic thrombocytopenic purpura.
39 Tpo levels are not elevated in human immune thrombocytopenic purpura.
40 n, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura.
41 develop a practice guideline for idiopathic thrombocytopenic purpura.
42 nia gravis, pemphigus vulgaris or thrombotic thrombocytopenic purpura.
43 Adamts13(-/-) mice in a model of thrombotic thrombocytopenic purpura.
44 odies against ADAMTS13 that cause thrombotic thrombocytopenic purpura.
45 enic target for autoantibodies in thrombotic thrombocytopenic purpura.
46 , a condition only experienced in thrombotic thrombocytopenic purpura.
47 while ADAMTS13 deficiency causes thrombotic thrombocytopenic purpura.
48 sistance, multiple sclerosis, and idiopathic thrombocytopenic purpura.
49 MPO were characteristic for acute thrombotic thrombocytopenic purpura.
50 eatening disorder called acquired thrombotic thrombocytopenic purpura.
51 mbocytopenia in patients with chronic immune thrombocytopenic purpura.
52 r microangiopathies, particularly thrombotic thrombocytopenic purpura.
53 Among the 130 newly diagnosed patients with thrombocytopenic purpura, 108 (83%; age 43 [30-52]; 73%
54 y was hereditary spherocytosis (111), immune thrombocytopenic purpura (36), sickle cell disease (SCD)
56 d a molecular distinction between thrombotic thrombocytopenic purpura, a disease characterized by a l
57 uman endothelial cells and causes thrombotic thrombocytopenic purpura, a disease with similarities to
58 insights into the pathophysiology of immune thrombocytopenic purpura, a disorder in which autoantibo
62 on the status of current research in immune thrombocytopenic purpura and a preview of agents in deve
64 tomy occurred in 82% of patients with immune thrombocytopenic purpura and hematocrit level increased
65 microangiopathy (TMA), including thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome,
66 ation between ticlopidine use and thrombotic thrombocytopenic purpura and other adverse effects, clop
67 us to understand pathogenesis of thrombotic thrombocytopenic purpura and other arterial thromboses a
68 ld be an antithrombotic agent for thrombotic thrombocytopenic purpura and other thrombotic conditions
69 f any treatment for patients with idiopathic thrombocytopenic purpura and persistent severe thrombocy
70 ascular occlusion associated with thrombotic thrombocytopenic purpura and sepsis was revealed by the
71 munoglobulin G from patients with thrombotic thrombocytopenic purpura and sequence alignment of the A
72 ceptable for patients with refractory immune thrombocytopenic purpura and severe thrombocytopenia wit
73 ions including arthritis, cancer, thrombotic thrombocytopenic purpura and the Ehlers-Danlos type VIIC
74 alikes and their distinction from thrombotic thrombocytopenic purpura and the hemolytic uremic syndro
76 0% of patients diagnosed with primary immune thrombocytopenic purpura, and are not associated with di
77 rlying Helicobacter pylori-associated immune thrombocytopenic purpura, and Ghevaert et al. describe a
78 are no specific tests that define idiopathic thrombocytopenic purpura, and management decisions are o
80 gnosis between inherited and acquired immune thrombocytopenic purpura as well as clinical practice on
81 orders, such as rheumatoid arthritis, immune thrombocytopenic purpura, autoimmune hemolytic anemia, s
82 us platelet disorders, especially idiopathic thrombocytopenic purpura, before consideration of therap
83 pathy and a possible diagnosis of thrombotic thrombocytopenic purpura between Jan 8, 2004, and Dec 6,
84 be the most important therapy in thrombotic thrombocytopenic purpura, but clinical data for adjuncti
85 gy published a practice guideline for immune thrombocytopenic purpura, but treatment recommendations
86 ypical hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, C3GN, and dense deposit diseas
88 Deaths have been reported for 2.9% of immune thrombocytopenic purpura cases treated with rituximab, b
89 tient suffers from a rare form of idiopathic thrombocytopenic purpura caused by a GPVI-specific autoa
90 hritis, systemic lupus erythematosus, immune thrombocytopenic purpura, chronic cold agglutinin diseas
91 ma exchange in some patients with thrombotic thrombocytopenic purpura; conversely such deficiency is
93 dying 20 patients with congenital thrombotic thrombocytopenic purpura (cTTP) who cannot cleave VWF mu
94 Patients suffering from acquired thrombotic thrombocytopenic purpura develop autoantibodies directed
95 y findings in 11 patients in whom thrombotic thrombocytopenic purpura developed during or soon after
97 and the pathogenesis of clinical thrombotic thrombocytopenic purpura, especially in relation to ADAM
99 s for the diagnosis and management of immune thrombocytopenic purpura focused entirely on primary dis
100 re more than 16 years of age, had idiopathic thrombocytopenic purpura for more than 3 months, had a p
101 lasma from 37 patients with acute thrombotic thrombocytopenic purpura had severe deficiency of von Wi
102 of intravenous Rh immune globulin for immune thrombocytopenic purpura has been reported with an estim
104 the pathophysiology of idiopathic thrombotic thrombocytopenic purpura have provided the rationale for
105 itial management of patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-
108 cy, making their distinction from thrombotic thrombocytopenic purpura-hemolytic uremic syndrome diffi
109 ment the reports of occurrence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome durin
111 greatest risk for development of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome is ne
114 women with congenital or familial thrombotic thrombocytopenic purpura-hemolytic uremic syndrome who w
115 crease the risk for occurrence of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.
117 ish aHUS from other TMAs, such as thrombotic thrombocytopenic purpura; however, novel bioassays are b
118 is), 6; hemolytic uremic syndrome-thrombotic thrombocytopenic purpura (HUS/TTP), 8; systemic lupus er
120 or the treatment of acute and chronic immune thrombocytopenic purpura in children and chronic immune
121 unding the diagnosis and treatment of immune thrombocytopenic purpura in children continue to evolve.
123 evision of the present guidelines for immune thrombocytopenic purpura in pregnancy based on evidence-
124 ples of plasma from patients with thrombotic thrombocytopenic purpura in remission or in 74 plasma sa
125 S13 deficiency is associated with thrombotic thrombocytopenic purpura, in which life-threatening epis
126 Hematology and British guidelines on immune thrombocytopenic purpura incidence, prevalence, and natu
127 ia, antiphospholipid syndrome and thrombotic thrombocytopenic purpura, include immunosuppression and
128 n patients with acute episodes of thrombotic thrombocytopenic purpura, independent of ADAMTS13 activi
129 cidence of ticlopidine-associated thrombotic thrombocytopenic purpura is 1 per 1600 to 5000 patients
131 Treatment of chronic refractory idiopathic thrombocytopenic purpura is a dilemma because many patie
138 e onset of ticlopidine-associated thrombotic thrombocytopenic purpura is difficult to predict, despit
139 ed by thrombotic microangiopathy, thrombotic thrombocytopenic purpura is distinguished by a severe de
140 ing protease activity in acquired thrombotic thrombocytopenic purpura is due to an autoantibody inhib
144 about the incidence and prevalence of immune thrombocytopenic purpura is limited, with nearly all dat
145 l investigation of novel therapies in immune thrombocytopenic purpura is undergoing a revolution that
146 d between ChAdOx1 vaccination and idiopathic thrombocytopenic purpura (ITP) (0-27 d after vaccination
147 Most current treatments for chronic immune thrombocytopenic purpura (ITP) act by decreasing platele
148 ction in North American patients with immune thrombocytopenic purpura (ITP) and the effect of H pylor
149 ine if megakaryocytes are targeted by immune thrombocytopenic purpura (ITP) autoantibodies, as are pl
150 treatment for adult patients with idiopathic thrombocytopenic purpura (ITP) for more than 50 years.
151 marrow patient and a patient with Idiopathic Thrombocytopenic Purpura (ITP) for the same platelet con
154 Guidelines for management of acute immune thrombocytopenic purpura (ITP) in childhood were publish
167 FcgammaR-dependent cytopenias such as immune thrombocytopenic purpura (ITP) or autoimmune hemolytic a
169 somes as a new treatment strategy for immune thrombocytopenic purpura (ITP) through the use of a mous
170 allow adults with recently diagnosed immune thrombocytopenic purpura (ITP) who had failed an initial
171 of immune-related diseases, including immune thrombocytopenic purpura (ITP), autoimmune neuropathies,
173 ites in 23 countries with chronic idiopathic thrombocytopenic purpura (ITP), platelet counts less tha
174 destructive disorders, including idiopathic thrombocytopenic purpura (ITP), posttransfusion purpura
175 s, the authors concluded that, in idiopathic thrombocytopenic purpura (ITP), production of platelets
184 adult patients (n = 137) with classic immune thrombocytopenic purpura (ITP; n = 156) or human immunod
185 Insights into immune-mediated thrombotic thrombocytopenic purpura (iTTP) pathophysiology have led
191 ell-characterized murine model of autoimmune thrombocytopenic purpura, male (NZW x BXSB) F1 mice (W/B
192 eral systemic diseases, including thrombotic thrombocytopenic purpura, manifest much of their patholo
194 ts, hypertension (n = 2) and immune-mediated thrombocytopenic purpura (n = 1), were possibly related
196 management decisions in suspected thrombotic thrombocytopenic purpura, new evidence supporting the ef
197 of the pathological mechanisms of thrombotic thrombocytopenic purpura not only provide a rationale fo
199 ts and children with acute or chronic immune thrombocytopenic purpura or HIV-related thrombocytopenia
200 sseminated intravascular coagulation, immune thrombocytopenic purpura, or splenic sequestration did n
202 n plasma from patients with acute thrombotic thrombocytopenic purpura, patients with other diseases,
203 es to be indicated for idiopathic thrombotic thrombocytopenic purpura regardless of ADAMTS13 levels,
204 urring in patients with inherited thrombotic thrombocytopenic purpura, resulted in a significant redu
205 associated with diseases such as thrombotic thrombocytopenic purpura, sepsis, and diabetes among oth
206 f delivery of a pregnant patient with immune thrombocytopenic purpura should be determined based on m
207 oglobulin preparation in treatment of immune thrombocytopenic purpura suggests that other mechanisms
208 receiving alemtuzumab developed late immune thrombocytopenic purpura that remitted with standard the
210 d with myelodysplastic syndromes, idiopathic thrombocytopenic purpura, thrombocytopenia due to human
213 ich includes two major disorders: thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic synd
218 Recovery from acute episodes of thrombotic thrombocytopenic purpura (TTP) appears complete except f
219 leading to idiopathic, autoimmune thrombotic thrombocytopenic purpura (TTP) by identifying naturally
221 eceived a diagnosis of hereditary thrombotic thrombocytopenic purpura (TTP) due to severe ADAMTS13 de
222 haemolytic uraemic syndrome (HUS)/thrombotic thrombocytopenic purpura (TTP) during an Escherichia col
248 (APS), atypical presentations of thrombotic thrombocytopenic purpura (TTP) or heparin-induced thromb
249 factor (VWF)-cleaving protease implicated in thrombocytopenic purpura (TTP) pathogenesis was identifi
250 c ADAMTS13 activity in congenital thrombotic thrombocytopenic purpura (TTP) patients is constrained b
252 mal plasma, and its deficiency in thrombotic thrombocytopenic purpura (TTP) patients, provides additi
253 Although both aHUS and acquired thrombotic thrombocytopenic purpura (TTP) remain clinical diagnoses
254 ive treatment, most patients with thrombotic thrombocytopenic purpura (TTP) survive the acute TTP epi
256 activity is the primary cause of thrombotic thrombocytopenic purpura (TTP) whereas overwhelming acti
257 f plasma ADAMTS13 activity causes thrombotic thrombocytopenic purpura (TTP), a life-threatening syndr
258 key factor in the pathogenesis of thrombotic thrombocytopenic purpura (TTP), a life-threatening throm
261 n effective empiric treatment for thrombotic thrombocytopenic purpura (TTP), but how therapy affects
262 may precipitate acute episodes of thrombotic thrombocytopenic purpura (TTP), but pregnancy outcomes i
263 d to a life-threatening disorder, thrombotic thrombocytopenic purpura (TTP), characterized by platele
264 t advances have demonstrated that thrombotic thrombocytopenic purpura (TTP), characterized by widespr
265 ted with platelet transfusions in thrombotic thrombocytopenic purpura (TTP), heparin-induced thromboc
266 aHUS from other TMAs, especially thrombotic thrombocytopenic purpura (TTP), is difficult due to over
267 immune thrombocytopenia (ITP) and thrombotic thrombocytopenic purpura (TTP), respectively, illuminate
268 molytic-uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP), the histories and presen
291 le in pathogenesis of the disease thrombotic thrombocytopenic purpura (TTP); however, experimental ev
292 TTP cases from the United Kingdom Thrombotic Thrombocytopenic Purpura (UK TTP) Registry with clinical
293 ssociated with the development of thrombotic thrombocytopenic purpura, usually within 1 month of init
297 However, patients with chronic idiopathic thrombocytopenic purpura who harbor predominantly young
299 itors, and the risk of relapse of thrombotic thrombocytopenic purpura will be important to further va
300 ease platelet counts in patients with immune thrombocytopenic purpura, without significant adverse ef