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1 ring 1971 to 1991 and followed for mortality through 1992.

2 Dementia was ascertained through 2013 using cognitive exams, telephone interviews

3 gery for GERD in 2000 to 2012 with follow-up through 2014, and the outcome was surgical reinterventio

4 hin one metropolitan health system from 2005 through 2015.

5 index admissions for PCI and CABG from 2013 through 2016 at BPCI hospitals and matched control hospi

6 care showed substantial increases from 1996 through 2016, with the highest increases in population-a

7 elevated risk of persistent stunting from 12 through 24 months with a relative risk ratio of 1.51 (95

8 th higher scores indicating better function) through 24 weeks.

9 trolled, double-blinded trial, 444 adults 60 through 64 years of age were randomized to receive eithe

10 7 adults of white European ancestry, aged 45 through 79 years, participating in the Atherosclerosis R

11 lieves the negative regulatory effect of ATP through a 2.5- angstrom-resolution crystal structure of

12 l of organ growth and patterning is executed through a balanced regulation of progenitor self-renewal

13 e time of a stochastic process first passing through a boundary is important to many diverse applicat

14 69C) triggers increased intracellular Ca(2+) through a Ca(2+)/calmodulin-dependent protein kinase II

15 mechanism for injection-induced earthquakes through a case study of the 2017 M(w) 5.5 induced earthq

16 m and molecular weights greater than 65 kDa, through a combination of intra- and intermolecular metal

17 Through a combination of proteomics and gene expression

18 This connection is revealed through a combination of scanning PTE and electron micro

19 roadmap to 2025, we should create more unity through a common knowledge hub linking academia, industr

20 gel that, at one temperature, could be moved through a constriction under a magnetic field and, at a

21 potent antibodies specific for the pathogen through a Darwinian evolutionary process known as affini

22 example of apple by-products (AP) recycling through a designed fermentation by selected autochthonou

23 Besides the syn-addition mechanism through a four-center transition state, radical and pola

24 toresponsive systems in aqueous environments through a full spectrometric approach combined with a si

25 ct readout of H3K27me3 by BAHCC1 is achieved through a hydrophobic trimethyl-L-lysine-binding 'cage'

26 oprotein gene lpp promoted capsule retention through a mechanism dependent on its C-terminal lysine r

27 lanoma cells can adapt to targeted therapies through a mechanosignaling loop involving the autocrine

28 alous diffusion was characterized by FT-FRAP through a nonlinear fit to multiple spatial harmonics of

29 henylphosphino)methane) that was synthesized through a one-pot reaction using [Ag(pz)](n) as precurso

30 emporary creation of pores in cell membranes through a phenomenon called sonoporation by high-intensi

31 T cells to the cytokine interleukin-2 (IL-2) through a positive feed-forward loop involving increased

32 different climates to balance survival and, through a post-vernalization effect, reproductive output

33 during homeostasis, TM keratinocytes transit through a proliferative CP state and exhibit directional

34 -lines and two patient tumour tissue samples through a qPCR instrument and finally piloted on an ISFE

35 dent on tryptophan by regulating YtgR levels through a rare triple-tryptophan motif (WWW) in the YtgC

36 SPCL was achieved through a sequential three segment ligation on a polymer

37 exciton transfer from silicon to anthracene through a single 15 ns Dexter energy transfer step with

38 The conductance through a single molecule can be measured by contacting

39 iates the transcriptional repression of Wapl through a single Pax5-binding site by recruiting the pol

40 (ICL) is rationally designed to stabilize Sn through a structural reconstruction mechanism.

41 irus-1 and-2, Vaccinia virus, and Zika virus through a type I interferon (IFN)-independent mechanism.

42 covery in vivo in a spinal cord injury model through a unique mechanism of anti-inflammation-based fi

43 anic compounds from hydrothermal vent fluids through a unique solid phase microextraction (SPME) samp

44 rance of this method is extensively examined through a variety of substrates, including synthesis and

45 Here, we demonstrate translational read-through across two evolutionarily conserved, in-frame st

46 tations which stabilise target cell activity through activity-dependent global scaling have been obse

47 macaques, we analyzed multiple brain regions through acute and chronic infection (90 days postinfecti

48 e occurrence of verbal bullying was verified through adolescents' self-report.

49 ein interactions from outside binding motifs through altered RNA secondary structure.

50 hat stromal Lama5 regulated immune responses through altering LN structures and T cell behaviors.

51 minal BON domain binds anionic phospholipids through an extensive membrane:protein interface.

52 s move unidirectionally without intervention through an external force field or a patterned track.

53 olecular mechanisms of CASQ2-CPVT was sought through an international multicenter collaboration.

54 hogenesis of FXII-, ANGPT1-, and U-HAE moves through an unbalanced control of kallikrein activity, wi

55 tic lethal interactions with the loss of VHL through analysis of primary tumor genomic and transcript

56 in wild-type cells also repressed virulence through aphB We further show that ompR expression was no

57 th ENaC primarily has been tested indirectly through assays of channel function.

58 es (HDACs) repress cardiomyocyte hypertrophy through association with the prohypertrophic transcripti

59 mioid clade of Agaricales and was maintained through at least 160 million years of evolution.

60 of intracellular levels of anticancer drugs through ATP-binding cassette (ABC) pumps.

61 We reviewed 3328 articles through August 14, 2020 and identified 25 studies with 3

62 and finally amplify the prescribed sequence through autonomous formation of a signaling concatemer.

63 distinct from that of conventional B cells, through B cell receptor (BCR)-dependent positive selecti

64 urrents of tens of nanoamperes, which flowed through both homogeneous and non-homogeneous base-pair s

65 First, we demonstrated through both PCR and immunostaining that mouse lymphatic

66 Behavioural change was measured through caregiver interview.

67 Thus, Rb dilution through cell growth in G(1) provides one of the long-sou

68 major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggreg

69 es are regulated in a tissue-specific manner through co-assembly with beta subunits KCNE1-5.

70 r cells recruited to the premetastatic lungs through complement C5a receptor 1 signaling.

71 finement of AF and stroke prediction schemes through comprehensive digital phenotyping using structur

72 l radiology personnel expertise is augmented through comprehensive education.

73 Here, through comprehensive filtration, we prioritized rs71987

74 icroscope geometry, including cell migration through confined spaces within a microfluidic device, su

75 ert neuroprotective roles in CNS homeostasis through continued refinement of synaptic connections.

76 re treated with 5-Fluorouracil for five days through continuous perfusion and cell viability was anal

77 regulates cell proliferation and organ size through control of the transcriptional regulators YAP (y

78 kin and extracted pharmacokinetic parameters through convolutional neural network-based image process

79 power can be transmitted over long distances through corrosion-free, lightweight fiber optic cables.

80 We then imparted light sensitivity through covalent attachment of a synthetic glutamate-bas

81 We hypothesized that ATP transfer rate through creatine kinase (CK) (k(f)(CKrest)) would be inc

82 Cellular cholesterol levels are regulated through crosstalk between the plasma membrane (PM), wher

83 itically important in vegetative propagation through cuttings in some plants, especially woody specie

84 differential chromatin interaction detection through data augmentation under preserved false discover

85 ic Study of Atherosclerosis (MESA) from 1996 through December 31, 2015, the final day of follow-up.

86 shaped the diversification of these enzymes through deep time.

87 G1 and G2, the insertion site is recognized through defined mechanisms, at least in members examined

88 necessary for transcriptional regulation but through different mechanisms.

89 of tumor fibrosis in lung cancer is mediated through differential SMAD3 promoter methylation in TAFs

90 tent pro-invasive and pro-metastatic effects through directly binding to Vimentin and competitively a

91 ' framework which studies physical transport through disordered media allows us to formulate precise

92 rentiated subsets mediate immunosurveillance through diverse peripheral sites.

93 We report that L1 activity triggers FOA through DNA damage-driven apoptosis and the complement s

94 nally, we show that LukE targets murine Darc through DR1 in vivo to cause host lethality.

95 ted material, and modulates fluxes of carbon through Earth's largest terrestrial carbon reservoir.

96 of the mechanisms underlying EE is mediated through enhanced MeCP2 SUMOylation and increased Wnt6 ex

97 loss by enhancing osteoclast differentiation through enhanced TNFalpha signaling.

98 tend the classic transfer learning framework through ensemble and demonstrate its general utility wit

99 galovirus (HCMV) causes a lifelong infection through establishment of latency.

100 We observe the opposite: signal flow through even the longest cones (0.4-mm axons) is essenti

101 e isolated and comprehensively characterized through exhaustive analytical methods which detail the m

102 Manipulation of the LFP has occurred mostly through experiment, giving rise to a variety of semiempi

103 Through extensive simulation studies, the analyses of PE

104 formance of our Bayesian inference procedure through extensive simulations, showing that our approach

105 ns: free IgE initiated allergic inflammation through FcepsilonRI on allergic effector cells, while Ig

106 als whose long-term fate requires assessment through field trials.

107 Active maintenance of beta-cell identity through fine-tuned regulation of key transcription facto

108 d 20 age-matched controls, using a HOA-based through-focus analysis performed on the logNS IQ metric

109 ynergy with metabolic stress-activated FOXO1 through formation of a complex.

110 ethod to functionalize peptides and proteins through free-radical-mediated dechalcogenation.

111 as irrigation water not only benefits crops through fulfilling crops' water demand but also creates

112 y of the CF(2)Br intermediates was showcased through functionalization to a variety of enantioenriche

113 as a treatment target and should be refined through future research, patient input, and clinical stu

114 (FAS), is produced in the soma and delivered through gap junctions to the germline; there it is used

115 the modulation of PP-InsPs influence the ESR through general stress response transcription factors Ms

116 formation is commonly processed in the brain through generation of antagonistic responses to differen

117 Here, we infer the history of vertebrates through genomic comparisons with a new chromosome-scale

118 ing the effect of future research investment through global collaborative efforts and partnerships.

119 extreme or selectively with protein targets through good mimicry at the other).

120 ission could be continuously tuned from blue through green to orange, as well as outputted as a white

121 s) dissolve into shallow groundwater or pass through groundwater systems to the atmosphere.

122 tein-bound Mn(4)CaO(x) complex, which passes through >=5 intermediate states in the water-splitting c

123 les the emergence of antiandrogen resistance through heterogeneous mechanisms.

124 men, 0.36; Blacks, 0.90; Whites, 0.50; up to/through high-school education, 1.00; beyond high-school

125 sigma-bond formations were found to proceed through highly ordered cyclic or bicyclic transition sta

126 c ultrastructure and skin dermis of MFS mice through immunohistochemical evaluation and quantificatio

127 vel method of photodynamic effect evaluation through in situ detection of specific protein oxidation

128 Through incompletely defined mechanisms, CovR/S and RocA

129 ors can efficiently inactivate coronaviruses through incorporation into HVAC ducts or recirculating a

130 the next generation of two-step VT complexes through incorporation of mixed-valence class II and clas

131 ressures and shift towards ocean stewardship through incorporation of niche innovations within and ac

132 strategies based on fostering carbon storage through increased tree diversity.

133 ypti promoted arbovirus emergence not solely through increased vector-host contact but also as a resu

134 that folding-upon-binding primarily occurred through induced-folding pathways (in which intermolecula

135 OFF response is mediated by the S-ON pathway through inhibitory input from an undiscovered S-cone ama

136 Gliomas are currently classified through integration of histology and mutation informatio

137 the ability to adhere to the surrounding ECM through integrin receptors, we examined the hypothesis t

138 nt of donor bacterial pneumonia promotes PGD through ischemia/reperfusion-primed donor TRAMs.

139 the L-type pore-forming alpha1 subunit and, through its C-terminal region, scaffolds the beta subuni

140 und hotspots and the nascent chromosome axis through its component cohesin pREC8.

141 Furthermore, our analysis demonstrates that through its functional resemblance to an ear horn (aka e

142 proposed to exert its antidepressant effects through its metabolite (2R,6R)-hydroxynorketamine ((2R,6

143 Ahnak, through its N-terminal region, scaffolds the L-type pore

144 ene robustly silenced transcription and read through its polyadenylation sequence.

145 okine that regulates immune cell homeostasis through its recruitment to a high-affinity heterotrimeri

146 an endocrine role in whole body homeostasis through its varied secretome that targets distant adipos

147 r of Controlled Trials from January 1, 1990, through July 1, 2019.

148 y associated with greater iron concentration through late adolescence and young-adulthood.

149 Through LC-MS/MS analysis, we discover that majority of

150 nstants of K(+), Cu(2+), and Cl(-) diffusing through loblolly pine (Pinus taeda) cell wall layers und

151 ffecting impalement under ambient conditions through local changes in the droplet curvature.

152 Action potentials propagate through long axons to their postsynaptic partners, which

153 n known cancer-related genes detectable only through long-read sequencing.

154 s alters blood-brain barrier (BBB) integrity through loss of tight junction protein claudin-5 (cldn5)

155 d PARP1 as an interacting partner for IAV HA through mass spectrometry analysis.

156 From mid-February through May 2020, 206,000 (95% credible interval, 178,10

157 ered by US community health centers in March through May 2020, including SARS-CoV-2 testing, well-chi

158 zation regulate cardiac fibroblast phenotype through mechanical activation of p38-YAP-TEAD signaling,

159 estasis-mediated cell death and inflammation through mechanisms involving activation of the inflammas

160 eys, a circuit from superior colliculus (SC) through medial-dorsal nucleus of the thalamus (MD) to fr

161 AMI has been a target of financial penalties through Medicare.

162 et channels are typically conducted off-line through microscopic image analysis, or by first collecti

163 n of cohesin from chromatin as cells transit through mitosis.

164 outcomes of U.S. invasive Hia cases detected through multi-state surveillance during 2011-2015.

165 rain, nanomaterials may induce neurotoxicity through multiple mechanisms including the oxidative stre

166 nd particles in microfluidic systems flowing through multiple outlet channels are typically conducted

167 n the integration of extracellular signaling through multiple receptors, including the T-cell recepto

168 loss attributed to elevated oxidative stress through NADPH oxidase in lineage-traced microglia.

169 m, which contributes to the robustness of TC through natural variation in GI and ZTL alleles found on

170 Key architectures obtained through NCA ROP or in combination with other polymerizat

171 cycle one, once every 3 weeks in cycles two through nine, and once every 4 weeks thereafter as maint

172 and the shares of health spending channelled through non-profit and private insurance are ambiguous.

173 veal a critical, noncatalytic role for Exo1, through noncanonical interaction with polo kinase.

174 prion protein interacts with copper, Cu(II), through octarepeat and nonoctarepeat (non-OR) binding si

175 ted passively across the Escherichia coli OM through OmpF.

176 culus) were evaluated by calibrated dentists through oral examinations.

177 Thinking through other minds creatively situates the free-energy

178 that the free energy principle and Thinking Through Other Minds will be useful in achieving it.

179 gnized connection between these two pathways through our discovery that human aminolevulinic acid deh

180 much higher levels mediates neuronal injury through oxidative stress.

181 vely effluxed out of normal proximal tubules through P-glycoprotein transporter while being retained

182 cal for agonist binding and biased signaling through PAR4.

183 t that functional redundancy can be achieved through parallelization of molecularly distinct but func

184 tion of these predator-induced trait changes through particular communities remains a challenge.

185 nsferred to adjacent epidermal keratinocytes through pathways that involve microtubule networks and t

186 ere driven by disruption of the WNT pathway, through preventing the binding of TCF4 to chromatin.

187 ities, endured bleaching, and then recovered through proliferation of heat-tolerant symbionts.

188 on of several ABA-responsive genes, probably through promoting the recruitment of RNA polymerase II t

189 t system CpxRA directly senses acidification through protonation of CpxA periplasmic histidine residu

190 ic, and lung cell lines triggered cell death through PTCH proapoptotic signaling.

191 s, both involving ESAA relief, were explored through quantum chemical calculations and experiments.

192 The genesis of novel influenza viruses through reassortment poses a continuing risk to public h

193 Imbalanced 5-HT1A/2A activation, either through receptor-specific drug intake, genetically predi

194 esemia has been linked to insulin resistance through reduced tyrosine kinase activity of the insulin

195 a new mechanism for social memory formation, through regulating synaptic receptor trafficking in pyra

196 ant Wnt signaling drives a number of cancers through regulation of diverse downstream pathways.

197 sociated genetic mutations that may function through regulation of m7G methylation.

198 like transcriptional program to induce ABCB1 through remodeling and activation of an ATF4-bound, stre

199 NF and dampened inflammatory gene expression through reverse signaling.

200 Gene silencing through RNAi has been used successfully in a broad range

201 haromyces cerevisiae, depends on progression through S phase of the cell cycle, but the molecular nat

202 mage induced by bedaquiline and moxifloxacin through secondary effects downstream from their main tar

203 (beta2M) and affects class I Ag presentation through sequestration of beta2M inside endoplasmic retic

204 c acids that target specific RNA transcripts through several mechanisms.

205 We evaluated MIXnorm through simulations and cancer studies.

206 We demonstrate through simulations that NExUS outperforms existing netw

207 Fgl2 as a soluble TFR cell effector molecule through single-cell gene expression profiling.

208 t the extent to which CodY exerts its effect through small regulatory RNAs (sRNAs).

209 his transformation has been studied in-depth through stoichiometric reactions of the key diazatitanac

210 eration bifunctional inhibitors was achieved through structure-based inhibitor design.

211 fluences genome-wide chromatin accessibility through subtle refinement of H2A.Z patterns, providing a

212 Polymerization occurs through successive intermolecular hydroarylation reactio

213 roscopic colitis (n= 13,957) were identified through Systematized Nomenclature of Medicine codes from

214 inine deprivation treatment and chemotherapy through targeting ASS1- and GLUT1-mediated arginolysis a

215 be necessary to improve consumer acceptance through technological processes prior to marketing.

216 y role in the resolution of, and replication through, telomeric G-quadruplexes.

217 L interact with COP1 and undergo degradation through the 26S proteasome pathway in the dark.

218 severe steroid resistant asthma, potentially through the accumulation of pathogenic IL5(+) IL17A(+) C

219 However, impeding PERK-phosphorylation through the administration of GSK2656157 abrogated neuro

220 It was only recently, through the advent of high-throughput technologies, that

221 controls and 126 patients with fibromyalgia) through the analysis of their blood plasma using attenua

222 nd street-scale FFCO(2) emissions estimation through the atmospheric CO(2) inversion process.

223 opportunities for pursuing these strategies through the Bat One Health Research Network (BOHRN).

224 Here, we report that octopamine activity through the beta-adrenergic-like receptor Octbeta1R driv

225 pable of modulating innate immune signalling through the cGAS-STING pathway.

226 Earth's microbial biosphere extends down through the crust and much of the subsurface, including

227 a reveal a distinct mode of LPS action that, through the disruption of the early coordinated non-lyti

228 EGF receptor to induce downstream signaling through the ERK serine/threonine kinase and the Fos tran

229 Proton flow through the F(o) motor generates rotation of the central

230 V) is a common infection that is transmitted through the fecal-oral route, shed in the stool of infec

231 requires close contact and generally occurs through the fecal-oral route.

232 elective and reversible binding to acetylene through the formation of metastable [Ni(II)(C(2)H(2))(3)

233 collected from 54 BI-ALCL patients diagnosed through the French Lymphopath network.

234 ses of cytomegalovirus-specific T cells, and through the generation and in vivo monitoring of defined

235 port at 32 degrees C, permissive conditions, through the Golgi apparatus was locally delayed, almost

236 sic questions as whether vesicular transport through the Golgi occurs in an anterograde (from entry t

237 ed structures in the Universe and are formed through the gravitational accretion of matter over cosmi

238 During entry, viruses must navigate through the host endomembrane system, penetrate cellular

239 rtance of inflammation and immune regulation through the IL18-IL18RAP axis and antigen presentation i

240 The mere requirement to this end is through the increase of temperature.

241 criptional complex driving melanoma invasion through the induction of the sialyltransferase ST3GAL1.

242 Through the integration of transcriptomics, in situ hybr

243 tions showed that oBA derivatives olefinated through the isolated (N, O)(Ph, C(6)H(4), C) oxaphosphet

244 ed the flow and flux of small molecule drugs through the layers and structures of ex vivo nude mouse

245 re at the appressorial base(1-4), forcing it through the leaf cuticle where it elongates invasive hyp

246 For RQDs, increasing the CdS shell volume through the length elongation has no effect on either th

247 olve movements of the bulky transport domain through the lipid bilayer.

248 t-network sprawl-that is, sprawl as measured through the local connectivity of the street network.

249 in regulating mitochondrial calcium dynamics through the lysosomal calcium efflux channel, transient

250 (RLR) are cytosolic RNA sensors that signal through the MAVS adaptor to activate IFN responses again

251 t the third metal ion assists the departure, through the mobile arch, of the nucleotide monophosphate

252 es (PTs) and affects intracellular responses through the modulation of Ca(2+) signaling, actin organi

253 erexpression activated the NF-kappaB pathway through the NF-kappaB transcription-activating group P65

254 ntrol pathogenesis and mosquito transmission through the nonstructural protein 3 helicase.

255 e natural reservoir, posing a risk to humans through the occasional emergence of novel strains with e

256 icated by the transport processes of stimuli through the papilla matrix to reach taste receptors, pro

257 overwintering biennial plants transport Suc through the phloem from photosynthetic source tissues to

258 PI3K lipid kinases signal through the PI3K/Akt pathway, regulating cell growth and

259 cells correlated positively with one another through the premalignancy cascade, indicating that incre

260 in triplicate, and of the device selectivity through the presence of an internal reference electrode.

261 lieved to orchestrate MS pathology, in part, through the production of two proinflammatory cytokines:

262 Through the quantitative analysis of the localization of

263 The pivotal one involves a resolution, through the quinine- or quinidine-promoted methanolysis

264 ing decoded, whereas escalated amplification through the recruitment of second-order neurons boosts n

265 outstanding scientists and expand knowledge through the scientific method.

266 interaction sculpts intratumor heterogeneity through the selection of immune-evasive clones.

267 ime control of the ultrasound dose delivered through the skull is necessary as the range of pressure

268 the nucleosome H2A/H2B acidic patch regions through the SMARCB1 C-terminal alpha-helix and the SMARC

269 th sensitivity~70-90% and specificity~90-93% through the sparse regression machine learning of patter

270 rs of follow-up, 44% of YBMSM initiated PrEP through the study after a median of 122 days.

271 ectivity of the reaction, which can be tuned through the substituents of the heteronorbornadienic sys

272 In this work, we investigate this matter through the temporal regulation of initiation in a livin

273 inducing macrophage and platelet activation through the TLR4 pathway.

274 region is required for nuclear import of Gag through the TNPO3 pathway.

275 maturation and refolding malformed proteins through the unfolded protein response (UPR).

276 Guided by chromatin structure, through the use of Chromosome Conformation Capture (3C),

277 de spin centers with variable concentrations through the use of mixed crystals containing the seconda

278 of the incomplete and non-canonical NAD caps through their decapping, deNADding and pyrophosphohydrol

279 nators affect rates of plant diversification through their effects on pollen dispersal.

280 d that targeted interventions can guide them through their neuronal differentiation.

281 ugation of shishijimicin A enediyne payloads through their phenolic moiety represents a novel approac

282 as Hsp20 are maintained post-translationally through their recognition, disassembly, and degradation

283 Through this approach, we find that cholesterol in the t

284 onstitutively active YAP were able to travel through this capillary plexus, reenter systemic circulat

285 Through this polar DprA targeting function, sigma(X) med

286 long been considered relatively more stable through time compared to the conditions on land.

287 oss their lifetime (i.e., followed from 2015 through to death), and result in a health-related net mo

288 athing (SDB), which includes primary snoring through to obstructive sleep apnea syndrome (OSAS), may

289 This balance may be maintained through trade-offs where migrants gain survival benefits

290 Hippocampal theta thus supports learning through two interleaved processes: strengthening encodin

291 ive K-Ras4B dimerizes in silico and in vitro through two major interfaces: (i) beta-interface, mapped

292 e regulation of p53 transcriptional activity through tyrosine phosphorylation.

293 notypic testing, and (5) variant correlation-through which a clinician can distinguish a molecular fi

294 RNA interference (RNAi) is a natural process through which double-stranded RNA molecules can silence

295 provides a high-resolution map of eRNA loci through which super-enhancer activities can be quantifie

296 The development of tools through which the ISR can be modulated promises to uncov

297 ture of these fluctuations and the paradigms through which they arise remain debated.

298 n regions; and (ii) understand the mechanism through which verubecestat might cause hippocampal (and

299 dendrochronological record provides a window through which we can understand how tree size and traits

300 ope can retrieve this near-field information through wide-field optics in a spatially resolved manner