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1 , mycophenolic acid (MPA), selenazofurin, or tiazofurin.
2 the active metabolite of the antitumor drug tiazofurin.
3 of nicotinamide riboside and the cancer drug tiazofurin.
4 e the effects of GTP on in situ TG activity, tiazofurin, a drug that selectively decreases GTP levels
6 e 5'-monophosphate (MMP), and beta-methylene-tiazofurin adenine dinucleotide (TAD) were determined.
10 well as the synergistic interaction between tiazofurin and ADP differ significantly from those of th
11 homonas foetus and human type 2 IMPDHs using tiazofurin and ADP, which bind in the nicotinamide and a
12 lls an order of magnitude more potently than tiazofurin, and MAD analogues were resistant to glucuron
14 -dependent proteolysis due to the effects of tiazofurin, because in vitro GTP protects tTG against pr
15 cells (IC50 = 1.1 microM) more potently than tiazofurin (IC50 = 12.4 microM) or mycophenolic acid (IC
17 ine as a target and mycophenolic acid (MPA), tiazofurin, or ribavirin, which are inhibitors of IMP de
19 SH-SY5Y cells with a combination of MTX and tiazofurin resulted in significantly less in situ TG act
20 metabolic conversion of the anticancer agent tiazofurin to its active form tiazofurin adenine dinucle